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Clin Microbiol Infect. 2015 Dec 8. pii: S1198-743X(15)00991-X. doi: 10.1016/j.cmi.2015.11.009. [Epub ahead of print] Isolation of live Borrelia burgdorferi sensu lato spirochaetes from patients with undefined disorders and symptoms not typical for Lyme borreliosis. Rudenko N1, Golovchenko M2, Vancova M3, Clark K4, Grubhoffer L5, Oliver JH Jr6. Author information

• 1Biology Centre Czech Academy of Sciences, Institute of Parasitology, Ceske Budejovice, Czech Republic; Georgia Southern University, The James H. Oliver Jr Institute for Coastal Plain Sciences, Statesboro, GA, USA. Electronic address: [email protected].

• 6Georgia Southern University, The James H. Oliver Jr Institute for Coastal Plain Sciences, Statesboro, GA, USA.

Abstract Lyme borreliosis is a multisystem disorder with a diverse spectrum of clinical manifestations, caused by spirochaetes of the Borrelia burgdorferi sensu lato complex. It is an infectious disease that can be successfully cured by therapy in the early stages; however, the possibility of the appearance of persistent signs and symptoms of disease following antibiotic treatment is recognized. It is known that Lyme borreliosis mimics multiple diseases that were never proven to have a spirochaete aetiology.

Using complete modified Kelly-Pettenkofer medium we succeeded in cultivating live B. burgdorferi sensu lato spirochaetes from samples taken from people who suffered from undefined disorders, had symptoms not typical for Lyme borreliosis, but who had undergone antibiotic treatment due to a suspicion of having Lyme disease even though they were seronegative. We report the first recovery of live B. burgdorferi sensu stricto from residents of southeastern USA and the first successful cultivation of live Borrelia bissettii-like strain from residents of North America. Our results support the fact that B. bissettii is responsible for human Lymeborreliosis worldwide along with B. burgdorferi s.s. The involvement of new spirochaete species in Lyme borreliosis changes the understanding and recognition of clinical manifestations of this disease. https://www.youtube.com/watch?feature=youtu.be&v=V5CGYBuRBX4&app=desktop

Proc Natl Acad Sci U S A. 2011 Aug 30;108(35):14643-8. doi: 10.1073/pnas.1019074108. Epub 2011 Aug 15. Conjugative DNA transfer into human cells by the VirB/VirD4 type IV secretion system of the bacterial pathogen Bartonella henselae. Schröder G1, Schuelein R, Quebatte M, Dehio C.

Author information

• 1Biozentrum, University of Basel, 4056 Basel, Switzerland.

Abstract

Bacterial type IV secretion systems (T4SS) mediate interbacterial conjugative DNA transfer and transkingdom protein transfer into eukaryotic host cells in bacterial pathogenesis. The sole bacterium known to naturally transfer DNA into eukaryotic host cells via a T4SS is the plant pathogen Agrobacterium tumefaciens. Here we demonstrate T4SS-mediated DNA transfer from a human bacterial pathogen into human cells. We show that the zoonotic pathogen Bartonella henselae can transfer a cryptic plasmid occurring in the bartonellae into the human endothelial cell line EA.hy926 via its T4SS VirB/VirD4. DNA transfer into EA.hy926 cells was demonstrated by using a reporter derivative of this Bartonella-specific mobilizable plasmid generated by insertion of a eukaryotic egfp-expression cassette. Fusion of the C-terminal secretion signal of the endogenous VirB/VirD4 protein substrate BepD with the plasmid-encoded DNA-transport protein Mob resulted in a 100-fold increased DNA transfer rate. Expression of the delivered egfp gene in EA.hy926 cells required cell division, suggesting that nuclear envelope breakdown may facilitate passive entry of the transferred ssDNA into the nucleus as prerequisite for complementary strand synthesis and transcription of the egfp gene. Addition of an eukaryotic neomycin phosphotransferase expression cassette to the reporter plasmid facilitated selection of stable transgenic EA.hy926 cell lines that display chromosomal integration of the transferred plasmid DNA. Our data suggest that T4SS-dependent DNA transfer into host cells may occur naturally during human infection with Bartonella and that these chronically infecting pathogens have potential for the engineering of in vivo gene-delivery vectors with applications in DNA vaccination and therapeutic gene therapy

This is just a summary of the association of Borrelia/Lyme Disease with a variety of medical conditions.

Cancer Alan McDonald 5 cases of brain cancer Sarcoidosis CFS Me

Most Common Lyme Disease Associated Auto Immune System Diseases (Lyme present in all) These all have Peer Reviewed and Published Medical Research proving the connection

PART 1 (The secondary lists are below) 1. Atrial Fibrillation 2. ALS - Amyotrophic lateral sclerosis – Lou Gehrig’s Disease 3. Alzheimer’s disease 4. Arthritis 5. Autism 6. Bell's palsy (Bell's palsy is defined as an idiopathic unilateral facial nerve paralysis) 7. Cardiac Disease 8. Cardiomegaly 9. Cardiomyopathy 10. Carditis 11. Carpal tunnel syndrome 12. Chronic encephalomyelitis 13. CFS - Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis; Systemic Exertion Intolerance Disease 14. Chronic muscle weakness 15. CRPS - Complex regional pain syndrome 16. Dementia 17. Demyelinating disorders 18. Dermatomyositis 19. Depression 20. Eczema 21. Encephalitis 22. Encephalomyelitis 23. Encephalopathy 24. Endometriosis 25. Epstein-Barr Virus 26. Erythema chronicum migrans 27. Fever 28. Fibromyalgia 29. Gastrointestinal Disorders 30. Graves’ disease 31. Guillain-Barre syndrome 32. Hashimoto's thyroiditis 33. Headaches (severe) 34. Hearing loss 35. Heart block 36. Hypothyroidism 37. Irritable Bowel Syndrome 38. Isolated acute myocarditis 39. Isolated lymphadenopathy 40. Isolated neuritis of the sciatic nerve 41. Isolated oculomotor nerve paralysis 42. Lyme Disease Co-infections (main): Borrelia Burgdorferi, Bartonella, Babesia Microti, Anaplasma Phagocytophila, Ehrlichiosis (HE, HME), Rickettsia 43. Lupus - Systemic Lupus Erythematosus 44. Ménière's Disease 45. Mental, Depression, Psychological problems 46. Memory loss 47. Migraine headaches 48. Mitochondria Disease 49. MND (Motor Neuron Disease) 50. Multiple Sclerosis (MS) 51. Multiple System Atrophy 52. Myasthenia gravis 53. Myositis (Muscle tissue inflammation) 54. Narcolepsy 55. Ocular problems 56. Parkinson’s disease 57. Parvovirus 58. POTS; Postural orthostatic tachycardia syndrome, also postural tachycardia syndrome 59. Psoriasis 60. Psoriatic Arthritis 61. Raynaud's syndrome 62. Rheumatic Fever 63. Rheumatoid Arthritis 64. Rocky Mountain Spotted Fever 65. Sarcoidosis 66. Scleroderma 67. Seizures and Neurological disorders 68. Sjögren’s Syndrome 69. Skin and Dermatological manifestations 70. Systemic Scleroderma 71. Thyroiditis 72. Tinnitus 73. Tourettes Syndrome 74. Transverse Myelitis 75. Vertigo 76. West Nile Virus

Heart Disease, POTS, Atrial Fibrillation, Rheumatic Heart Disease and the Lyme Disease Connection Borrelia infection as a cause of Carditis (a long-term study) http://www.ncbi.nlm.nih.gov/pubmed/11233466?dopt=Abstract Lyme Carditis: cardiac abnormalities of Lyme disease http://www.ncbi.nlm.nih.gov/pubmed/6967274?dopt=Abstract Lyme Carditis http://www.sciencedirect.com/…/article/pii/S0891552007001250 Patterns of orthostatic intolerance: The orthostatic tachycardia syndrome and adolescent chronic fatigue http://www.jpeds.com/article/S0022-3476(99)70025-9/abstract Ventricular tachycardia associated with Lyme Carditis http://www.ahjonline.com/arti…/0002- 8703(91)90173-F/abstract Three sudden cardiac deaths associated with Lyme Carditis - United States, November 2012 - July 2013 http://www.ncbi.nlm.nih.gov/pubmed/24336130 Lyme Carditis: clinical characteristics of 105 cases http://europepmc.org/abstract/med/1947815 Complete heart block due to Lyme Carditis http://europepmc.org/abstract/med/12777681 Cardiac Involvement in Lyme Disease: Manifestations and Management http://www.sciencedirect.com/…/artic…/pii/S002561961262775X… Lyme Carditis: An Important Cause of Reversible Heart Block http://annals.org/article.aspx?articleid=702950 Fatal Lyme Carditis and endodermal heterotopia of the atrioventricular node http://pmj.bmj.com/content/66/772/134.short An Epidemiologic Study of Lyme Disease in Southern Sweden http://www.nejm.org/doi/full/10.1056/NEJM199511163332004 Early disseminated Lyme disease: Cardiac manifestations http://www.sciencedirect.com/…/artic…/pii/S0002934399800412… Lyme Carditis: Electrophysiologic and histopathologic study http://www.sciencedirect.com/sci…/article/…/0002934386903700 Clinical presentation and Management of patients with hyperadrenergic postural orthostatic tachycardia syndrome. A single center experience On PDF (go to www.scholar.Google.com type in Clinical presentation and management of patients with hyper adrenergic postural orthostatic tachycardia syndrome Selective Anti-Inflammatory Action of Interleukin-11 in Murine Lyme Disease: Arthritis Decreases while Carditis Persists http://jid.oxfordjournals.org/content/179/3/734.short Carditis in Lyme disease susceptible and resistant strains of laboratory mice infected with Borrelia burgdorferi http://europepmc.org/abstract/med/1503192 Lyme Carditis: Cardiac Abnormalities of Lyme Disease http://annals.org/article.aspx?articleid=694150 Lyme Carditis and Borrelia-Associated Dilated Cardiomyopathy http://link.springer.com/artic…/10.1023%2FA%3A1009859817705… Postural orthostatic tachycardia syndrome following Lyme disease http://www.ncbi.nlm.nih.gov/pubmed/21305487 Postural Orthostatic Tachycardia Syndrome: A Clinical Review http://www.sciencedirect.com/…/article/pii/S0887899409003452 A Tale of Two Syndromes: Lyme Disease Preceding Postural Orthostatic Tachycardia Syndrome http://onlinelibrary.wiley.com/…/10.1111/anec.12158/abstract What you need to know about Lyme Carditis http://www.cdc.gov/lyme/signs_symptoms/lymecarditis.html Lyme borreliosis as a cause of myocarditis and heart muscle disease http://www.ncbi.nlm.nih.gov/pubmed/1915460?dopt=Abstract Electrocardiography of myocarditis revisited: Clinical and prognostic significance of electrocardiographic changes http://www.sciencedirect.com/sci…/article/…/000287039290613Z Fatal Pancarditis in a Patient with Coexistent Lyme Disease and Babesiosis: Demonstration of Spirochetes in the Myocardium http://annals.org/article.aspx?articleid=699906 Pericardial and Myocardial Disease http://www.slremeducation.org/…/Chapter-82.-Pericardial-and… Myocarditis, pericarditis and other pericardial diseases http://heart.bmj.com/content/84/4/449.short POTS http://lymemd.blogspot.com/2012/04/pots.html AUTONOMIC INSTABILITY & LYME http://www.lymeinfo.net/autonomic.html Spinal anaesthesia for caesarean delivery in a parturient with babesiosis and Lyme disease http://www.columbia-lyme.org/research/abstracts.html

Arthritis is Lyme Disease WERE YOU DIAGNOSED WITH ARTHRITIS? Your doctor was WRONG! Here is the medical proof that was not mentioned.

Chronic septic arthritis caused by Borrelia burgdorferi http://www.ncbi.nlm.nih.gov/pubmed/8242938 The persistence of spirochetal nucleic acids in active Lyme arthritis http://www.ncbi.nlm.nih.gov/pubmed/8093136 Detection of Borrelia burgdorferi DNA by Polymerase Chain Reaction in Synovial Fluid from Patients with Lyme Arthritis http://www.nejm.org/doi/full/10.1056/NEJM199401273300401 Neurologic complications of Lyme disease http://www.ncbi.nlm.nih.gov/pubmed/8265833?dopt=Citation Influence of arthritis-related protein (BBF01) on infectivity of Borrelia burgdorferi B31 http://www.ncbi.nlm.nih.gov/pubmed/23651628 Lyme arthritis and post-Lyme disease syndrome http://www.ncbi.nlm.nih.gov/pubmed/12118171 Musculoskeletal manifestations of Lyme disease http://www.sciencedirect.com/…/article/pii/S0002934399800436 Chronic widespread pain in the spectrum of rheumatological diseases http://www.sciencedirect.com/…/article/pii/S1521694211000040 Infectious agents in chronic rheumatic diseases http://journals.lww.com/…/Infectious_agents_in_chronic_rheu… Association of Chronic Lyme Arthritis with HLA-DR4 and HLA-DR2 Alleles http://www.nejm.org/doi/pdf/10.1056/NEJM199007263230402 Chronic Lyme Arthritis: Clinical and Immunogenetic Differentiation from Rheumatoid Arthritis http://annals.org/article.aspx?articleid=693095 Borrelia burgdorferi in Joint Fluid in Chronic Lyme Arthritis http://annals.org/article.aspx?articleid=700495 The pathogenesis of arthritis in Lyme disease: humoral immune responses and the role of intra-articular immune complexes http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2590026/ Lyme arthritis in a 12-year-old patient after a latency period of 5 years http://www.nutramedix.ec/…/283-lyme-arthritis-in-12-year-ol… Lyme arthritis. Spirochetes found in synovial microangiopathic lesions http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1887850/ The Clinical Evolution of Lyme Arthritis http://annals.org/article.aspx?articleid=702270 Childhood Lyme arthritis: Experience in an endemic area http://www.sciencedirect.com/…/article/pii/S0022347686806886 Clinical manifestations of Lyme disease http://www.sciencedirect.com/…/article/pii/S0176672486801237 Arthritis caused by Borrelia burgdorferi in dogs http://europepmc.org/abstract/med/3997648 Arthritis severity and spirochete burden are determined by serotype in the Borrelia turicatae- mouse model of Lyme disease http://iai.asm.org/content/65/1/285.short Joint manifestations of Lyme borreliosis in Europe http://europepmc.org/abstract/med/1947813 Diagnostic Accuracy of the Anti-Citrulline Antibody Assay for Rheumatoid Arthritis http://www.clinchem.org/content/47/6/1089.short Septic Arthritis http://www.sciencedirect.com/…/article/pii/S0140673697095226

Neurologic Manifestations of Lyme Disease

Chronic Neurologic Manifestations of Lyme Disease http://www.nejm.org/doi/full/10.1056/nejm199011223232102 Central Nervous System Manifestations of Lyme Disease http://archneur.jamanetwork.com/article.aspx… Neurologic Abnormalities of Lyme Disease http://journals.lww.com/…/Neurologic_Abnormalities_of_Lyme_… Neurologic Manifestations of Lyme Disease, the New “Great Imitator” http://cid.oxfordjournals.org/co…/…/Supplement_6/S1482.short The Early Clinical Manifestations of Lyme Disease http://annals.org/article.aspx?articleid=696718 Central Nervous System Manifestations of Lyme Disease http://archneur.jamanetwork.com/article.aspx… Headache Characteristics in Hospitalized Patients With Lyme Disease http://onlinelibrary.wiley.com/…/abstract;jsessionid=C7A37A… Tremor, seizures and psychosis as presenting symptoms in a patient with chronic lyme neuroborreliosis (LNB http://www.ncbi.nlm.nih.gov/pubmed/21648354

Alzheimer's and the Lyme Disease Connection- Indisputable Evidence!

Alzheimer Disease -- A Spirochetosis? http://link.springer.com/chapter/10.1007/978-1-4615- 8149-9_7 Lyme Disease Associated with Alzheimer’s Disease http://link.springer.com/article/10.1007/s00284-005-0454-7 Alzheimer Borreliosis http://alzheimerborreliosis.net/ Borrelia spirochaetes Detected in autopsy Alzheimer Brain by Dr. Alan MacDonald https://www.youtube.com/watch?v=44xL0z8I5X8 Alzheimer's & Lyme Disease: Is there a connection? https://www.youtube.com/watch?v=cF6QB52WYU0 The Lyme Disease, Alzheimer’s Connection http://mylymediseasetreatment.com/…/the- lyme-disease-alzhe…/ Lyme neuroborreliosis and dementia http://www.ncbi.nlm.nih.gov/pubmed/24762944 Concurrent neuroborreliosis and alzheimer's disease: Analysis of the evidence http://www.sciencedirect.com/sci…/article/…/0046817789900683 Concurrent Neocortical Borreliosis and Alzheimer's Disease http://onlinelibrary.wiley.com/…/j.1749-6632.1988.…/abstract Chronic Neurologic Manifestations of Lyme Disease http://www.nejm.org/doi/full/10.1056/nejm199011223232102 Plaques of Alzheimer’s disease originate from cysts of Borrelia burgdorferi, the Lyme disease spirochete http://www.sciencedirect.com/…/article/pii/S0306987706001551 Borrelia burgdorferi persists in the brain in chronic Lyme neuroborreliosis and may be associated with Alzheimer disease http://www.ncbi.nlm.nih.gov/pubmed/15665404 Practice parameters for the diagnosis of patients with nervous system Lyme borreliosis (Lyme disease) http://www.neurology.org/content/46/3/619.short Biology and neuropathology of dementia in syphilis and Lyme disease http://www.miklossy.ch/…/ChapterHandbookClinNeurolFinalPdf.… Chronic Inflammation and Amyloidogenesis in Alzheimer's Disease -- Role of Spirochetes http://www.ncbi.nlm.nih.gov/pubmed/18487847 Regional Cerebral Blood Flow and Cognitive Deficits in Chronic Lyme Disease http://neuro.psychiatryonline.org/…/abs/10.1176/jnp.15.3.326 The many faces and phases of borreliosis I. Lyme disease http://www.sciencedirect.com/sci…/article/…/019096229070196O Rapidly progressive frontal-type dementia associated with Lyme disease http://www.ncbi.nlm.nih.gov/pubmed/7580195 Lyme Neuroborreliosis: Manifestations of a Rapidly Emerging Zoonosis http://www.ajnr.org/content/30/6/1079.short A study on the association between infectious burden and Alzheimer's disease. http://www.ncbi.nlm.nih.gov/pubmed/24910016 Bacterial infection and Alzheimer's disease: a meta-analysis http://www.ncbi.nlm.nih.gov/pubmed/25182736 Lipolysaccharide-Induced Neuroinflammation Is Associated with Alzheimer-Like Amyloidogenic Axonal Pathology and Dendritic Degeneration in Rats http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211261/ Neuropsychological Deficits in Lyme Disease Patients With and Without Other Evidence of Central Nervous System Pathology http://www.tandfonline.com/doi/abs/10.1207/s15324826an0601_1 Inflammation and central nervous system Lyme disease http://www.sciencedirect.com/…/article/pii/S0969996109003386 Alzheimer's disease and infection: Do infectious agents contribute to progression of Alzheimer's disease? http://www.sciencedirect.com/…/article/pii/S155252600802983X Inflammatory brain changes in Lyme borreliosis: A report on three patients and review of literature http://brain.oxfordjournals.org/content/119/6/2143.short Beta-amyloid deposition and Alzheimer's type changes induced by Borrelia spirochetes http://www.ncbi.nlm.nih.gov/pubmed/15894409 Emerging roles of pathogens in Alzheimer disease http://journals.cambridge.org/action/displayAbstract… Molecular and immunological evidence of oral Treponema in the human brain and their association with Alzheimer's disease http://onlinelibrary.wiley.com/…/j.0902- 0055.2001…/abstract… Role of Infection in the Pathogenesis of Alzheimer’s Disease http://link.springer.com/a…/10.2165/11310910-000000000-00000 Cerebral metabolic changes associated with Lyme disease http://journals.lww.com/…/Cerebral_metabolic_changes_associ… Initial Evaluation of the Patient with Suspected Dementia http://www2.jabsom.hawaii.edu/…/Initial%20Evaluation%20of%2… Biofilms of borrelia burgdorferi In Vitro Observations http://www.molecularalzheimer.org/ Lyme disease, Alzheimer’s disease, and Inflammation – the relationship http://canlyme.com/…/lyme-disease-alzheimers-disease-and-i…/ "Emerging Role of Infection in Alzheimer's Disease" -- and a Lyme/Alzheimer's link http://www.medhelp.org/…/Emerging-Role-of-Infe…/show/1666449 Lyme & Alzheimer’s http://lymehandbook.com/…/400-misdiagn…/430-lyme-alzheimers/ Alzheimers and spirochete DNA connection – Dr. Alan B. MacDonald http://lymehandbook.com/…/alzheimers-and-spiroche-dna-conn…/ Stroke, Meningitis, Alzheimer’s Caused by Lyme Disease [Video] http://guardianlv.com/…/stroke-meningitis-alzheimers-cause…/ Alzheimer's Linked To Lyme Disease, Keeping Your Memory Strong https://www.envita.com/…/alzheimers-linked-to-lyme-disease-… Lyme Disease and Cognitive Impairments http://www.mentalhealthandillness.com/…/LymeDiseaseAndCogni… Under Our Skin - Dr. McDonald Clip, Lyme Disease, Alzhemer's, MS https://www.youtube.com/watch?v=GCLwauRh2gQ Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171359/

Chronic or Late Lyme Neuroborreliosis: Analysis of Evidence Compared to Chronic or Late Neurosyphilis http://benthamopen.com/FULLTEXT/TONEUJ-6-146

Historic evidence to support a causal relationship between spirochetal infections and Alzheimer’s disease http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399390/

The medical industry simply ignores this research. There is an unspoken principle in medicine. "Deny the existence of immunosuppression and chronic infection wherever they can get away with it." The drugs and extended medical care for Alzheimer patients generates tens of billions of dollars for the industry. Treating the cause could cure or dramatically improve this infectious disease. Spirochetal infections of the brain along with active viruses cause Alzheimer’s and Dementia. They include the Lyme spirochete, the Syphilis spirochete, and less often the Leptospira spirochete.

Alzheimer's and Lyme Disease General articles http://www.molecularalzheimer.org/ http://alzheimerborreliosis.net/ http://www.ncbi.nlm.nih.gov/pubmed/24762944 http://www.j-alz.com/node/364 https://www.youtube.com/watch?v=44xL0z8I5X8 http://bebrainfit.com/…/lyme-disease-a-hidden-cause-of-men…/ http://canlyme.com/…/lyme-disease-alzheimers-disease-and-i…/ http://www.mdjunction.com/…/medic…/373919-alzheimers-or-lyme http://lymedisease.org/news/hardscienceonlyme/802.html http://www.medhelp.org/…/Emerging-Role-of-Infe…/show/1666449 http://lymehandbook.com/…/400-misdiagn…/430-lyme-alzheimers/ http://lymehandbook.com/…/alzheimers-and-spiroche-dna-conn…/ http://guardianlv.com/…/stroke-meningitis-alzheimers-cause…/ http://www.envita.com/…/alzheimers-linked-to-lyme-disease-k… http://www.mentalhealthandillness.com/…/LymeDiseaseAndCogni… http://lymediseaseresource.com/…/genetic-frankenstein-a-li…/ http://mylymediseasetreatment.com/…/the-lyme-disease-alzhe…/ http://www.vanityfair.com/…/06/qa-the-lyme-disease-controve… http://www.healinggrapevine.com/…/lyme-disease-aka-the-impo… http://www.youtube.com/watch?v=cF6QB52WYU0 http://www.cbsnews.com/…/alzheimers-disease-jumps-across-b…/ http://georgialymedisease.org/lyme_disease http://www.topsecretwriters.com/…/misdiagnosed-alzheimers-…/ http://www.usatoday.com/…/2013/09/03/lyme-disease-…/2757071/ http://articles.mercola.com/…/…/2013/09/04/lyme-disease.aspx http://www.medicalnewstoday.com/articles/159442.php http://mpkb.org/home/diseases/alzheimers_dementia Under Our Skin - Dr. McDonald Clip, Lyme Disease, Alzhemer's, MS and … https://www.youtube.com/watch?v=GCLwauRh2gQ https://www.facebook.com/notes/trying-to-eat-bathe-and-breathe-something-that-wont-kill-me/the- lyme-disease-alzheimers-connection-and-what-you-can-do-about-it/745104275528812 https://www.facebook.com/photo.php?fbid=10203711762828782&set=a.2490117906495.127448.165 9156865&type=1&theater Lyme Disease Misdiagnosed as Multiple Sclerosis Multiple Sclerosis and the Lyme Disease Connection

Multiple sclerosis is a chronic central nervous system infection by a spirochetal agent http://www.ncbi.nlm.nih.gov/pubmed/3357458?dopt=Abstract Lyme borreliosis and multiple sclerosis are associated with primary effusion lymphoma http://www.ncbi.nlm.nih.gov/pubmed/17197115… BRUCELLOSIS AND MULTIPLE SCLEROSIS http://jama.jamanetwork.com/article.aspx?articleid=295099 Borrelia burgdorferi antibodies in multiple sclerosis patients http://www.neurology.org/content/39/6/760.short Chronic Lyme borreliosis at the root of multiple sclerosis--is a cure with attainable? http://www.ncbi.nlm.nih.gov/pubmed/15617845?dopt=Abstract Isolated monolateral neurosensory hearing loss as a rare sign of neuroborreliosis. http://www.ncbi.nlm.nih.gov/pubmed/15060815?dopt=Abstract Differential diagnosis of posterior fossa multiple sclerosis lesions--neuroradiological aspects http://www.ncbi.nlm.nih.gov/pubmed/11794484?dopt=Abstract Lyme borreliosis and multiple sclerosis: any connection? A seroepidemic study. http://www.ncbi.nlm.nih.gov/pubmed/11153045 Multiple sclerosis vs Lyme disease: a case presentation to a discussant and a review of the literature http://www.ncbi.nlm.nih.gov/pubmed/10618695?dopt=Abstract Inflammatory brain changes in Lyme borreliosis. A report on three patients and review of literature http://www.ncbi.nlm.nih.gov/pubmed/9010017?dopt=Abstract Multiple sclerosis is Lyme disease: Anatomy of a cover-up http://owndoc.com/…/multiple- sclerosis-is-lyme-disease-ana…/ The presence of anti-Borrelia burgdorferi antibodies in a group of multiple sclerosis patients in eastern Sicily http://www.ncbi.nlm.nih.gov/pubmed/8249668?dopt=Abstract Multiple sclerosis or Lyme disease? a diagnosis problem of exclusion http://www.ncbi.nlm.nih.gov/pubmed/2388492?dopt=Abstract Neurologic manifestations of Lyme disease, the new "great imitator" http://www.ncbi.nlm.nih.gov/pubmed/2682960?dopt=Abstract Clinical pathologic correlations of Lyme disease http://www.ncbi.nlm.nih.gov/pubmed/2814170?dopt=Abstract Chronic central nervous system involvement in Lyme borreliosis http://www.ncbi.nlm.nih.gov/pubmed/3368066?dopt=Abstract The underdiagnosis of neuropsychiatric Lyme disease in children and adults http://www.ncbi.nlm.nih.gov/pubmed/9774805?dopt=Abstract Demyelinating encephalopathy in Lyme disease http://www.ncbi.nlm.nih.gov/pubmed/3969220?dopt=Abstract Argentine Patagonia: prevalence and clinical features of multiple sclerosis http://www.ncbi.nlm.nih.gov/pubmed/18566029 The Differential Diagnosis of Multiple Sclerosis http://journals.lww.com/…/The_Differential_Diagnosis_of_Mul… Lyme related to MS, Fibro, Parkinsons, Lupus, CFS, ALS, Autism and other conditions http://whatislyme.com/lyme-related-to-ms-fibro-parkinsons-…/ Is Multiple Sclerosis Lyme Disease Left Untreated? http://www.rense.com/general48/mutl.htm MS and Lyme Disease http://theness.com/neurologi…/index.php/ms-and-lyme-disease/ Lyme disease sufferer spent years being misdiagnosed http://www.ngnews.ca/…/Lyme- disease-sufferer-spent-years-…/1 Lyme Disease and MS: Similar or Same? http://lymepeople.com/lyme-disease-and-ms- similar-or-same/ Systemic Intracellular Bacterial Infections (Mycoplasma, Chlamydia, Borrelia species) in Neurodegenerative (Multiple Sclerosis, Amyotrophic Lateral Sclerosis, Alzheimer's) and Behavioral (Autistic Spectrum Disorders) Diseases http://www.townsendletter.com/Apri…/systemicintracel0408.htm Doctor, Do I have Lyme or MS http://lymemd.blogspot.com/…/doctor-do-i-have-lyme-or- ms.ht… The Lyme MS Connection MS sufferers PLEASE READ http://www.mdjunction.com/…/373883-the-lyme-ms-connection-m… All MS is Lyme disease http://www.dailystrength.org/…/discussions/messages/12179040 Lyme disease can masquerade as MS, ALS, even dementia and its numbers are growing tenfold. So why is Canada lagging behind in treating and diagnosing it? http://www.macleans.ca/…/heal…/the-truth-about-lyme-disease/ Mother diagnosed with MS and facing life in a wheelchair is cured - after she discovered her symptoms were due to a TICK BITE http://www.dailymail.co.uk/…/Mother-diagnosed-MS- facing-lif… Lyme disease is an illness caused by the organism Borrelia burgdorferi. Some of the neurologic symptoms of Lyme disease are similar to those of MS http://www.nationalmssociety.org/…/Other-Condi…/Lyme-Disease Lyme Disease Misdiagnosed as Multiple Sclerosis http://www.lymeinfo.net/multiplesclerosis.html Multiple Sclerosis Forum - Lyme Disease mimics MS http://ehealthforum.com/…/lyme- disease-mimics-ms-t131383.ht… When Lyme is Misdiagnosed as MS https://katinamakris.wordpress.com/…/when-lyme-is- misdiagn…/ http://lymehandbook.com/category/ms/ Lyme Disease II: MS and Lyme, Cover-ups and Conspiracies http://lymehandbook.com/…/lyme-disease-ii-ms-and-lyme-cove…/

Parkinson’s Disease and the Lyme Disease Connection

Lyme-associated parkinsonism: a neuropathologic case study and review of the literature http://www.ncbi.nlm.nih.gov/pubmed/12946221

The association between infectious burden and Parkinson's disease: A case-control study. http://www.ncbi.nlm.nih.gov/pubmed/26037459

Lyme disease patients' serum contains IgM antibodies to Borrelia burgdorferithat cross‐react with neuronal antigens http://www.neurology.org/content/38/9/1439.short

Antigen‐specific proliferation of CSF lymphocytes in Lyme disease http://www.neurology.org/content/35/11/1642.short

Psychiatric Comorbidity and Other Psychological Factors in Patients with “Chronic Lyme Disease” http://www.amjmed.com/article/S0002-9343(09)00342-8/abstract Interaction of the Lyme Disease Spirochete Borrelia burgdorferiwith Brain Parenchyma Elicits Inflammatory Mediators from Glial Cells as Well as Glial and Neuronal Apoptosis http://www.sciencedirect.com/…/article/pii/S0002944010615283

Antiscience and ethical concerns associated with advocacy of Lyme disease http://www.sciencedirect.com/…/article/pii/S1473309911700342

Role of inflammation in neurodegenerative diseases http://journals.lww.com/…/Role_of_inflammation_in_neurodege…

Neuropsychological effects of brain autograft of adrenal medullary tissue for the treatment of Parkinson's disease http://www.neurology.org/content/38/9/1442.short

Fatigue in neurological disorders http://www.sciencedirect.com/…/article/pii/S0140673604157942

Elevated levels of the 26K human hybridoma growth factor (interleukin 6) in cerebrospinal fluid of patients with acute infection of the central nervous system http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1541434/

Do early-life insults contribute to the late-life development of Parkinson and Alzheimer diseases? http://www.sciencedirect.com/…/article/pii/S0026049508002515

Functional Brain Imaging and Neuropsychological Testing in Lyme Disease http://cid.oxfordjournals.org/cont…/…/Supplement_1/S57.short

Nervous system Lyme disease: is there a controversy? http://europepmc.org/abstract/med/21964848

Polyneuritis cranialis in Lyme disease http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1028967/

Central nervous system Lyme disease http://link.springer.com/article/10.1007/s11910-005- 0032-1

Matrix Metalloproteinases in the Cerebrospinal Fluid of Patients with Lyme Neuroborreliosis http://jid.oxfordjournals.org/content/177/2/401.short

Lyme Disease Misdiagnosed as Alzheimer’s, Parkinson and… http://www.endowmentmed.org/pdf/updatelyme.pdf

Other Information http://www.parkinsonsresource.org/…/lyme-disease-a-parkins…/ Parkinsons disease is caused by spirochete and viral infections. Did you know Michael J Fox has Lyme disease? He said so on The Letterman show about 20 years ago. Borrelia burgdorferi, the spirochete that causes Lyme disease and many viruses are associated with Parkinsons disease. This study was in China. Unfortunately this will be ignored by the U.S. medical industry. Anyone with power or influence in the medical industry in the west does not want to reveal the cause of any disease if they can get away with it. Parkinsons disease patients generate billions of dollars in sales of medical products and services before they die. They won't give up that kind of money. The is a big part of it. They will ignore, reject, and lie if that is necessary to prevent studies like this from being accepted as valid in the west. 2015 Aug - The association between infectious burden and Parkinson's disease: A case- control study.

"METHODS: Antibody titers to common infectious pathogens including cytomegalovirus (CMV), Epstein Barr virus (EBV),herpes simplex virus type-1 (HSV-1), Borrelia burgdorferi (B. burgdorferi), Chlamydophila pneumoniae (C. pneumoniae) and Helicobacter pylori (H. pylori) were measured by ELISA in serum of 131 PD patients and 141 normal controls. Infectious burden (IB) was defined as a composite serologic measure of exposure to these common pathogens.... CONCLUSIONS: IB(infectious burden) consisting of CMV, EBV, HSV-1, B. burgdorferi(Lyme disease), C. pneumoniae and H. pylori is associated with PD. This study supports the role of infection in the etiology of PD." http://www.ncbi.nlm.nih.gov/pubmed/26037459 Lyme Disease and Parkinson’s http://www.blog.parkinsonsrecovery.com/catego…/lyme- disease/ http://www.gordonmedical.com/unravelling-complex-chronic…/…/ https://puttinglymebehindyou.wordpress.com/…/lyme-disease-…/ M.S., Parkinson's, or Simply Lyme Disease? http://issuesoncall.blogspot.com/…/ms-parkinsons-or-simply-…

NEWS: Complicated case of soldier diagnosed with Parkinson's, then Lyme http://lymedisease.org/…/lyme_disease_views/soldier-lym.html Lyme’s Disease – An Epidemic? A Cause for Parkinson’s and Other Neurodegenerative Disorders? http://blog.themidwaycenter.com/?p=96

Crohn’s Disease and the Lyme Disease Connection

Gastrointestinal Pathology in Children with Lyme Disease http://www.lymepa.org/05%20GI%20pathology%20with%20Lyme%20d… These bacilli were from a polyp in the small intestine of the Lyme patient. http://www.lymephotos.com/bb/index.html PRACTICAL GASTROENTEROLOGY http://www.thehumansideoflyme.net/viewarticle.php?aid=62 Lyme, CHF, Rhabdomyolysis and Crohn's http://lymemd.blogspot.com/…/lyme-chf- rhabdomyolysis-and-cr… Causation of Crohn's disease by Mycobacterium avium subspecies paratuberculosis http://www.ncbi.nlm.nih.gov/pubmed/10888733 Does Mycobacterium avium subspecies paratuberculosis cause Crohn’s disease? http://gut.bmj.com/content/54/7/896.extract Ulcerative colitis and Crohn's disease: is Mycobacterium avium subspecies paratuberculosis the common villain? http://www.gutpathogens.com/content/2/1/21 The evidence for Mycobacterium paratuberculosis in Crohn's disease http://www.ncbi.nlm.nih.gov/pubmed/18043227 The Mycobacterium avium subspecies paratuberculosis problem and its relation to the causation of Crohn disease http://www.who.int/water_sanitation_hea…/…/patmycrobact6.pdf https://www.tcd.ie/…/specifically%20stained%20bacteria%206.… Isolation of Mycobacterium avium Subspecies paratuberculosis Reactive CD4 T Cells from Intestinal Biopsies of Crohn's Disease Patients http://journals.plos.org/plosone/article… Survival and Dormancy of Mycobacterium avium subsp. paratuberculosis in the Environment http://aem.asm.org/content/70/5/2989.short http://www.huffingtonpost.com/…/lyme-disease-symptoms_b_876… http://www.crohnsforum.com/showthread.php?t=17705 http://doctoronnie.com/tick-awareness/ http://www.lymephotos.com/cercaria/index.html Most doctors admit they cannot cure the disease; one reason is that they say it goes into a cyst stage. http://www.lymephotos.com/ehrlichia/index.html Ehrlichia; Nematomorphs feed on bacteria. Does this explain the necessity for colonization, forming one being, allowing them to be motile? http://www.healingwell.com/community/default.aspx… http://originsofhealth.com/…/get-educated-about-lyme-disea…/ http://www.lymeneteurope.org/forum/viewtopic.php?f=6&t=245 Lyme Disease: Looking beyond Borrelia | Natural Nutmeg Magazine naturalnutmeg.com › Conditions May 1, 2011 - In this article, we will review some Lyme Basics, including what Lyme is, how ... Lyme disease is caused by the bacterial spirochete Borrelia burgdorferi. ....Gastrointestinal Lyme disease may mimic colitis or Crohn's disease. http://mylymediseasetreatment.com/lyme-disease-symptoms/ Many Lyme patients were firstly diagnosed with other illnesses such as Juvenile Arthritis, Rheumatoid Arthritis, Reactive Arthritis, Infectious Arthritis, Osteoarthritis, Fibromyalgia, Raynaud’s Syndrome, Chronic Fatigue Syndrome, Interstitial Cystis, Gastroesophageal Reflux Disease, Fifth Disease, Multiple Sclerosis, scleroderma, lupus, early ALS, early Alzheimers Disease, crohn’s disease, ménières syndrome, reynaud’s syndrome, sjogren’s syndrome, irritable bowel syndrome, colitis, prostatitis, psychiatric disorders (bipolar, depression, etc.), encephalitis, sleep disorders, thyroid disease and various other illnesses. http://lymemd.blogspot.com/…/lyme-chf-rhabdomyolysis-and-cr… http://www.healthcaremagic.com/…/Blood-test-showed-Ly…/63631 http://canlyme.com/just-diagno…/testing/common-misdiagnoses/

Sarcoidosis and the Lyme Disease Connection

Determination of antibodies to Borrelia burgdorferi in sarcoidosis http://www.ncbi.nlm.nih.gov/pubmed/8036340 Borrelia burgdorferi infection may be the cause of sarcoidosis http://europepmc.org/abstract/med/1333393 Sarcoidosis and ELISA for Borrelia burgdorferi http://europepmc.org/abstract/med/8202765 High prevalence of ‘Borrelia-like’ organisms in skin biopsies of sarcoidosis patients from Western Austria http://onlinelibrary.wiley.com/…/j.1600-0560.2009…/abstract… Detection of Borrelia burgdorferi DNA in granulomatous tissues from patients with sarcoidosis using polymerase chain reaction in situ technique http://europepmc.org/abstract/med/9596840 Determination of antibody of Borrelia burgdorferi in the serum of patients with sarcoidosis and its significance http://europepmc.org/abstract/med/8045180 Granulomatous Cheilitis and Borrelia burgdorferi: Polymerase Chain Reaction and Serologic Studies in a Retrospective Case Series of 12 Patients http://archderm.jamanetwork.com/article.aspx… Seroprevalence of anti-Borrelia antibodies among patients with confirmed sarcoidosis in a region of Japan where Lyme borreliosis is endemic http://link.springer.com/article/10.1007/s004170050078… Could Borrelia burgdorferi be a causal agent of sarcoidosis? http://www.medical- hypotheses.com/…/0306-9877(89)…/abstract… Is there a role for microorganisms in the pathogenesis of sarcoidosis? http://onlinelibrary.wiley.com/…/j.1365-2796.2003.0107…/full Is sarcoidosis a borreliosis? http://europepmc.org/abstract/med/1669979 Is sarcoidosis a rickettsiosis? An archival study (Rickettsiosis is a Lyme disease co-infection) http://informahealthcare.com/…/abs/10.…/00365548.2011.554431 No serological evidence of Rickettsia helvetica infection in Scandinavian sarcoidosis patients http://www.researchgate.net/…/…/0deec52611f6346030000000.pdf

Epilepsy and the Lyme Disease Connection (the medical research)

Are you tired of treating it and managing it? Why not ELIMINATE IT FOR GOOD?

Intracranial aneurysms in three patients with disseminated Lyme borreliosis: cause or chance association? http://jnnp.bmj.com/content/64/5/636.short Epilepsy disclosing neuroborreliosis http://www.ncbi.nlm.nih.gov/pubmed/8009148 Inflammatory brain changes in Lyme borreliosis http://brain.oxfordjournals.org/content/119/6/2143.short Chronic Neurologic Manifestations of Erythema Migrans Borreliosis http://onlinelibrary.wiley.com/…/j.1749-6632.1988.…/abstract Parry–Romberg syndrome: A possible association with borreliosis http://onlinelibrary.wiley.com/…/j.1468-3083.2004…/abstract… Chronic neuroborreliosis by B. garinii: an unusual case presenting with epilepsy and multifocal brain MRI lesions http://www.newmicrobiologica.org/…/allegati_…/2014/3/393.pdf Seizures associated with use in patients with CNS disorders and renal insufficiency http://informahealthcare.com/…/a…/10.1080/00365540802375570… Epileptic seizure as initial and only manifestation of neuroborreliosis: case report http://link.springer.com/article/10.1007/s10072-014-1648-1 Range of atrioventricular conduction disturbances in Lyme borreliosis: a report of four cases and review of other published reports. http://heart.bmj.com/content/63/3/162.short Association of distinct species of Borrelia burgdorferi sensu lato with neuroborreliosis in Switzerland http://onlinelibrary.wiley.com/…/j.1469-0691.1997.tb00…/full

Motor neurone Disease/ALS? NOT!

NEWS: Told he was dying of ALS, California man turns it around with Lyme treatment http://lymedisease.org/news/lyme_disease_views/519.html… Lyme-Borreliose-Informationen http://www.lymenet.de/indexordner/ials.htm Chronic Lyme mistaken for ALS https://www.youtube.com/watch?v=ChC2Y2gOoJU

Amyotrophic lateral sclerosis (ALS) is Lyme Disease Lyme disease serology in amyotrophic lateral sclerosis http://onlinelibrary.wiley.com/…/10.1002/mus.21438/abstract… Systemic Intracellular Bacterial Infections (Mycoplasma, Chlamydia, Borrelia species) in Neurodegenerative (MS, ALS, Alzheimer’s) and Behavioral (Autistic Spectrum Disorders) Diseases http://www.researchgate.net/…/…/00b7d5142b0b7586ac000000.pdf Chronic Bacterial and Viral Infections in Neurodegenerative and Neurobehavioral Diseases http://labmed.ascpjournals.org/content/39/5/291.short Lyme disease -induced polyradiculopathy mimicking amyotrophic lateral sclerosis. http://www.ncbi.nlm.nih.gov/pubmed/24397499 Lyme & ALS http://lymehandbook.com/index/400-misdiagnoses/450-lyme-als/ ALS-like sequelae in chronic neuroborreliosis http://www.ncbi.nlm.nih.gov/pubmed/7610670?dopt=Abstract

Lyme disease -induced polyradiculopathy mimicking amyotrophic lateral sclerosis http://www.ncbi.nlm.nih.gov/pubmed/24397499

MOTOR NEURONS/AMYOTROPHIC LATERAL SCLEROSIS/LOU GEHRIG'S DISEASE/LYME DISEASE http://www.wellsphere.com/…/motor-neurons- amyotroph…/1191163

David Martz, the doctor who cured his ALS http://www.als-cure.com/als-cure/david-martz-cured-his-als/ Is It Really ALS? http://alsn.mda.org/article/it-really-als Systemic Intracellular Bacterial Infections (Mycoplasma, Chlamydia, Borrelia species) in Neurodegenerative (MS, ALS, Alzheimer’s) and Behavioral (Autistic Spectrum Disorders) Diseases http://www.nejm.org/doi/full/10.1056/NEJM199707033370105

Study: 9 in 10 ALS patients infected with Lyme bacteria http://www.als-cure.com/…/als-patients-infected-with-lyme-…/

Generalised motor neuron disease as an unusual manifestation of Borrelia burgdorferi infection http://jnnp.bmj.com/content/63/2/257.short

Chronic Neurologic Manifestations of Lyme Disease http://www.nejm.org/doi/full/10.1056/nejm199011223232102 Many PALS have Lyme http://www.als-cure.com/als-ly…/many-als-patients-have-lyme/ Myth: ALS is a disease http://www.als-cure.com/als-myths/als-is-not-a-disease/ Doctors told Steve Smith he was dying of ALS. He is now convinced that is not true http://www.igenex.com/strength.htm

Nervous system Lyme disease: is there a controversy? http://europepmc.org/abstract/med/21964848 ALS and Lyme Disease Questions from Patient and Families – Questions from Patient and Families – Responses from Medical Experts Responses from Medical Experts Responses from Medical Experts http://owndoc.com/pdf/ALS-disinfo.pdf Deliberate lies spread about ALS for financial gain http://www.als-cure.com/ Dying of Lyme disease: Case fatality rate nearly 100% http://owndoc.com/…/dying-of-lyme- disease-case-fatality-ra…/ Treatment of Amyotrophic Lateral Sclerosis and Multiple Sclerosis with Anti-Lyme Disease Antibiotics Being Used to Treat Lyme Disease http://www.waisbrenclinic.com/ALS-MS- lyme-disease.html

Practice parameters for the diagnosis of patients with nervous system Lyme borreliosis (Lyme disease) http://www.neurology.org/content/46/3/619.short

Reactivity of neuroborreliosis patients (Lyme disease) to cardiolipin and gangliosides http://www.jns-journal.com/ar…/0022-510X(93)90175-X/abstract Lyme Disease - Misdiagnoses and Medical Dictatorship http://www.rense.com/general43/kly.htm Primary lateral sclerosis: further clarification http://www.jns-journal.com/a…/S0022- 510X(01)00469-5/abstract Mechanisms and management of fatigue in progressive neurological disorders http://journals.lww.com/…/mechanisms_and_management_of_fati… Lack of antibodies to Borrelia burgdorferi in patients with amyotrophic lateral sclerosis http://europepmc.org/abstract/med/2911315 Immunologic Reactivity Against Borrelia burgdorferi in Patients With Motor Neuron Disease http://archneur.jamanetwork.com/article.aspx…

PCR detection of Borrelia burgdorferiDNA in cerebrospinal fluid of Lyme neuroborreliosis patients http://www.neurology.org/content/42/1/32.short

Neurological manifestations in Lyme borreliosis http://www.sciencedirect.com/sci…/article/…/0738081X9390095T Nervous System Lyme Borreliosis—Revisited http://archneur.jamanetwork.com/article.aspx… The NorVect Conference 2015 http://norvect.no/conference/conference-2015/speakers/ Simultaneous Human Granulocytic Ehrlichiosis and Lyme Borreliosis http://www.nejm.org/doi/full/10.1056/NEJM199707033370105 The Differential Diagnosis of Chronic Lyme Disease http://www.medscape.com/viewarticle/748084_3 ALS AND UNTREATED LYME DISEASE, BABESIA, BARTONELLA AND OTHER INFECTIONS http://www.personalconsult.com/…/als-untreated-lyme-and-oth…

NEWS: Told he was dying of ALS, California man turns it around with Lyme treatment http://lymedisease.org/news/lyme_disease_views/519.html…

Lyme-Borreliose-Informationen http://www.lymenet.de/indexordner/ials.htm Chronic Lyme mistaken for ALS https://www.youtube.com/watch?v=ChC2Y2gOoJU The ALSLYME Page http://www.angelfire.com/planet/lymedisease/7/ALSLYME.html Two Limestone women get reprieve from ALS diagnosis http://www.samento.com.ec/sciencel…/4lyme/2lymewomenals.html Geraghtys: Doctors pushed ALS diagnosis, ignored Lyme http://www.valleybreeze.com/…/geraghtys-doctors-pushed-als-…

Lupus and the Lyme Disease Connection

Borrelia infection and systemic lupus erythematosus http://www.ncbi.nlm.nih.gov/pubmed/2693342?dopt=Abstract The Fatigue Severity Scale: Application to Patients With Multiple Sclerosis and Systemic Lupus Erythematosus http://archneur.jamanetwork.com/article.aspx… Western Blotting in the Serodiagnosis of Lyme Disease http://jid.oxfordjournals.org/content/167/2/392.short Antibody Response in Lyme Disease: Evaluation of Diagnostic Tests http://jid.oxfordjournals.org/content/149/5/789.short The Spirochetal Etiology of Lyme Disease http://www.nejm.org/doi/pdf/10.1056/NEJM198303313081301 Study and treatment of post Lyme disease (STOP-LD) http://www.neurology.org/content/60/12/1923.short Enzyme-Linked Immunosorbent Assay and Indirect Immunofluorescence Assay for Lyme Disease http://jid.oxfordjournals.org/content/149/3/465.short Anticardiolipin antibodies in lyme disease http://onlinelibrary.wiley.com/…/10…/art.1780310818/abstract Antigens of Borrelia burgdorferi recognized during Lyme disease. Appearance of a new immunoglobulin M response and expansion of the immunoglobulin G response late in the illness http://www.ncbi.nlm.nih.gov/pmc/articles/PMC423723/ Neurologic Abnormalities of Lyme Disease http://journals.lww.com/…/Neurologic_Abnormalities_of_Lyme_… Cross-reactive idiotypes in sera from patients with leprosy, lupus and Lyme disease and from healthy individuals http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1534717/ http://onlinelibrary.wiley.com/…/j.1365-2249.1990.…/abstract Sequestration of antibody to Borrelia burgdorferi in immune complexes in seronegative Lyme disease http://www.thelancet.com/…/article/PII0140-6736(90…/abstract Immunoblot interpretation criteria for serodiagnosis of early Lyme disease http://jcm.asm.org/content/33/2/419.short Autoantibodies against cyclophilin in systemic lupus erythematosus and Lyme disease http://onlinelibrary.wiley.com/…/j.1365-2249.1992.…/abstract The Spectrum of Neurologic Disease Associated With Antiphospholipid AntibodiesLupus Anticoagulants and Anticardiolipin Antibodies http://archneur.jamanetwork.com/article.aspx… Serodiagnosis in early Lyme disease http://jcm.asm.org/content/31/12/3090.short Reactivity of neuroborreliosis patients (Lyme disease) to cardiolipin and ganglioside http://www.jns-journal.com/ar…/0022-510X(93)90175-X/abstract Immunodiagnostic tests for Lyme disease http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2590018/ Interactions of Phagocytes with the Lyme Disease Spirochete: Role of the Fc Receptor http://jid.oxfordjournals.org/content/150/4/497.short LYME MISDIAGNOSED AS LUPUS: IT HAPPENS EVERY DAY Title: The Pathologist's View of Lyme disease Authors: Hejka, England, Schmitz, Schell--Madison Source: Wisconsin Medical Journal 1989;88(11):17-20 "Lyme arthritis is FREQUENTLY mistaken clinically for rheumatoid arthritis, systemic lupus erythematous, or Reiter's syndrome. Synovial biopsies are probably the most frequent tissue examined microscopically from patients with Lyme disease. The histopathological spectrum ranges from chronic hyperplastic synovitis with effusions to erosive ostearthritis. (20)... "The disease captures the imagination of physicians, especially in endemic areas such as Wisconsin. Lyme disease is a multisystem disorder with protean manifestations ..."

Fibromyalgia and the Lyme Disease Connection

Lyme Disease Associated with Fibromyalgia http://annals.org/article.aspx?articleid=705732 Chronic Neurologic Manifestations of Lyme Disease http://www.nejm.org/doi/full/10.1056/nejm199011223232102 Neuroborreliosis http://www.sciencedirect.com/…/article/pii/S0002934399800448 Fibromyalgia and Parvovirus Infection (LD coinfection) http://onlinelibrary.wiley.com/…/10…/art.1780341018/abstract Emerging incidence of Lyme borreliosis, babesiosis, bartonellosis, and granulocytic ehrlichiosis in Australia http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258014/ Brief Report: Long-Term Assessment of Fibromyalgia in Patients With Culture-Confirmed Lyme Disease http://onlinelibrary.wiley.com/d…/10.1002/art.38972/abstract Symptom Overlap: Chronic Lyme and Chronic Fatigue Syndrome (Fibromyalgia) http://www.lymebabesiaphysician.com/…/lyme-and-fibromyalgia… Summary of the first 100 patients seen at a Lyme disease referral center http://www.sciencedirect.com/sci…/article/…/000293439090520N

CRPS - Complex Regional Pain Syndrome: Formally known as (RSD - Reflex Sympathetic Dystrophy) and the Lyme Disease Connection http://www.ncbi.nlm.nih.gov/pubmed/12478332 Complex regional pain syndrome and Lyme borreliosis: two different diseases? Sibanc B, Lesnicar G. Source Dept. of Infectious Diseases and Febrile Conditions, General Hospital Celje, Oblakova 5, SI- 3000 Celje, Slovenia. [email protected] Abstract Complex regional pain syndrome (CRPS) is a frequent complication appearing as pain of unexplained pathogenesis. Its association with Lyme borreliosis (LB) is fairly rare. In the presented clinical case, clinical features as well as the findings of radiological, radionuclide, neurophysiological and serological investigations pointed to an association between the two conditions. The patient fulfilled the criteria for both diagnoses, i.e. CRPS and LB. The subsequent antibiotic therapy resulted in a complete remission of both clinical entities. http://www.ncbi.nlm.nih.gov/pubmed/2095902 Enferm Infecc Microbiol Clin. 1990 Jan;8(1):32-5. [Reflex sympathetic dystrophy. A new manifestation of Lyme disease?]. [Article in Spanish] Gila L, Guerrero A, Astarloa R, Martí P, Gutiérrez JM. Source Servico de Neurología, Hospital Ramón y Cajal, Madrid. Abstract Several syndromes derived from the involvement of central and peripheral nervous system and meninges have been reported in the infection by Borrelia burgdorferi. The features of autonomic nervous system involvement have received a marginal attention. Reflex sympathetic dystrophy is an autonomic picture characterized by regional sympathetic hyperactivity which has not been associated with Lyme disease. We report a 16-year-old female with clinical, radiological and scintigraphic features consistent with reflex sympathetic dystrophy. The usual causes of this syndrome were ruled out and antibodies against Borrelia burgdorferi were detected by immunofluorescence, enzyme immunoassay and Western blotting. Specific IgG and IgM levels had a progressive increase during three months. In Lyme borreliosis causes of false positives were excluded. Antigen-antibody bands were detected in increasing number during the evolution, using sonicates of B. burgdorferi and patient's sera with the Western blotting technique. Our data suggest that reflex sympathetic dystrophy is another type of nervous system involvement in the multifaceted Lyme borreliosis. http://emedicine.medscape.com/article/1145318-differential http://flash.lymenet.org/ubb/ultimatebb.php/topic/1/125118 http://www.rsds.org/p…/deMosM_SturkenboomMCJM_HuygenFJPM.pdf Reflex sympathetic dystrophy with hidradenitis suppurativa exacerbation http://www.archives-pmr.org/…/S0003-9993(01)10804-X/abstract http://www.mdjunction.com/…/1457834-rsd-aka-crps-caused-by-… Jessica’s Journey http://hopeforjessica.blogspot.com/…/rsdlyme-connection.html

Epstein-Barr Virus and Lyme Disease Connection http://www.envita.com/…/key-uprooting-chronic-fatigue-syndr… Epstein-Barr virus and cytomegalovirus infections cause false-positive results in IgM two-test protocol for early Lyme borreliosis http://link.springer.com/article/10.1007%2FBF02561539… Serodiagnosis of Early Lyme Disease: Analysis of IgM and IgG Antibody Responses by Using an Antibody-Capture Enzyme Immunoassay http://jid.oxfordjournals.org/content/158/4/754.short Epidemiology and Clinical Manifestations of Lyme Borreliosis in Childhood http://onlinelibrary.wiley.com/…/j.1651-2227.1993.…/abstract A case-control study to assess possible triggers and cofactors in chronic fatigue syndrome http://www.amjmed.com/article/S0002-9343(96)00017-4/abstract Persistence of Serum Antibodies to Borrelia burgdorferi in Patients Treated for Lyme Disease http://cid.oxfordjournals.org/content/15/5/788.short Acute “idiopathic” peripheral facial palsy: Clinical, serological, and cerebrospinal fluid findings and effects of corticosteroids http://www.sciencedirect.com/sci…/article/…/0196070993900275 Peripheral Facial Palsy in Childhood-Lyme Borreliosis to be Suspected Unless Proven Otherwise http://onlinelibrary.wiley.com/…/j.1651-2227.1990.…/abstract

Endometriosis and the Lyme disease Connection Endometriosis-associated Lyme disease http://www.ncbi.nlm.nih.gov/pubmed/20143981 http://www.researchgate.net/…/41418397_Endometriosis-associ… Endometriosis-associated Lyme disease, Feb. 2010 http://www.mdjunction.com/…/1278213- endometriosisassociated… Multi-System Disease (MSD) http://www.vitalhealth.com/tre…/multi-system-disease- msd.php The co-occurrence of endometriosis with multiple sclerosis, systemic lupus erythematosus and Sjögren syndrome http://humrep.oxfordjournals.org/content/26/6/1555.short Endometriosis-associated Lyme http://informahealthcare.com/…/abs/10.3109/01443610903470270 Interstitial Cystitis and Borrelia burgdorferi http://annals.org/article.aspx?articleid=703382 Gynecologic Issues in Geriatric Women http://online.liebertpub.com/doi/abs/10.1089/jwh.2011.2803 High rate of allergies among women with endometriosis http://informahealthcare.com/…/abs/10.…/01443615.2011.644358

Lyme Disease and Eye Problems Strabismus, Diplopia and Ocular Manifestations with Lyme Disease

Five Cases of Paralytic Strabismus as a Rare Feature of Lyme Disease http://cid.oxfordjournals.org/content/48/6/756.full Paralytic strabismus as a manifestation of Lyme borreliosis http://www.ncbi.nlm.nih.gov/pubmed/16193697 Ocular manifestations of Lyme borreliosis in Europe http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659482/… Unusual Presentation of Lyme Disease: Horner Syndrome with Negative Serology http://www.jabfm.org/cgi/reprint/22/2/219.pdf Bartonella and intraocular inflammation: a series of cases and review of literature http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130920/ Diplopia as the first manifestation of Lyme disease http://www.ncbi.nlm.nih.gov/pubmed/12571776 Retrobulbar neuritis associated with Borrelia afzelii infection http://www.bmj.sk/2002/10302- 09.pdf Neuroretinitis as a manifestation of Lyme disease in South India: a case report http://www.ncbi.nlm.nih.gov/pubmed/20370334 Congenital Ptosis and Amblyopia http://www.healio.com/…/%7B…/congenital-ptosis-and- amblyopia Journal of Pediatric Ophthalmology and Strabismus March/April 2010 - Volume 47 · Issue 2: 101-104 Posted March 1, 2010

Ischaemic Optic Neuropathy in Lyme Disease http://informahealthcare.com/…/abs/10.3109/01658101003687294 Dacryoadenitis and Orbital Myositis Associated With Lyme Disease http://archopht.jamanetwork.com/article.aspx… Retrobulbar optic neuritis: a complication of Lyme disease? http://jnnp.bmj.com/content/78/12/1409.extract J Neurol Neurosurg Psychiatry 2007;78:1409-1410 doi:10.1136/jnnp.2006.113761 Ocular manifestations in children and adolescents with Lyme arthritis http://bjo.bmj.com/content/83/10/1149.short Bilateral idiopathic optic neuritis in pregnancy http://www.ncbi.nlm.nih.gov/pubmed/23305442 Semin Ophthalmol. 2013 Jan;28(1):46-9. doi: 10.3109/08820538.2012.735333. Suspecting Optic Neuritis, Diagnosing Bartonella Cat Scratch Disease http://archneur.jamanetwork.com/article.aspx… Bacterial tick-borne diseases caused by Bartonella spp., Borrelia burgdorferisensu lato, Coxiella burnetii, and Rickettsia spp. among patients with cataract surgery http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049946/ Lyme Disease and the Eyes http://www.lymeneteurope.org/forum/viewtopic.php?f=5&t=246

Eye Floaters and Lyme Disease Connection

Branch Retinal Artery Occlusion Associated With Lyme Disease http://archopht.jamanetwork.com/article.aspx… The expanding clinical spectrum of ocular Lyme borreliosis http://www.aaojournal.org/ar…/S0161-6420(99)00128-1/abstract CYTOLOGICALLY PROVEN SERONEGATIVE LYME CHOROIDITIS AND VITRITIS http://journals.lww.com/…/Cytologically_Proven_Seronegative… Intraocular-central nervous system lymphoma: Clinical features, diagnosis, and outcomes (Lymphoma is Lyme) http://www.sciencedirect.com/…/article/pii/S016164209990341X Ophthalmologic Complications of Systemic Disease http://www.sciencedirect.com/…/article/pii/S073386270700123X Lyme disease: A Look Beyond Antibiotics http://healinglymenaturally.webdesigncatalyst.com/…/LymeALo… Borrelia Hermsii Causing Relapsing Fever and Uveitis http://www.sciencedirect.com/…/article/pii/S0002939406003813 AN EYE ON INFLAMMATORY EYE DISEASE http://www.maneyonline.com/doi/abs/10.1179/acb.2005.044 The eye in systemic infection http://www.sciencedirect.com/…/article/pii/S0140673604172280 Panuveitis Caused by Borrelia Burgdorferi Sensu Lato Infection http://journals.lww.com/…/Panuveitis_Caused_by_Borrelia_Bur…

Spondylosis and the Lyme disease Connection http://www.ncbi.nlm.nih.gov/pubmed/24515913 http://canlyme.com/tag/spondylosis/ http://www.spineuniverse.com/…/spondyl…/arthritis-your-spine • Infections such as Lyme disease • Women are twice as likely to get arthritis http://www.klinghardtacademy.com/…/Herbs_used_in_treating_L… http://www.researchgate.net/…/260154370_Lumbosacral_multira…

Spondylolisthesis Spondylolisthesis is the forward displacement of a vertebra, especially the fifth lumbar vertebra, most commonly occurring after a break or fracture. Backward displacement is referred to as retrolisthesis. • Isthmic spondylolisthesis is the most common form; also called spondylolytic spondylolisthesis, it occurs with a reported prevalence of 5–7 percent in the US population. A slip or fracture of the intravertebral joint is usually acquired between the ages of 6 and 16 years, but remains unnoticed until adulthood. Roughly 90 percent of these isthmic slips are low-grade (less than 50 percent slip) and 10 percent are high-grade (greater than 50 percent slip).[2] • Degenerative spondylolisthesis is a disease of the older adult that develops as a result of facet arthritis and joint remodeling. Joint arthritis, and ligamentum flavum weakness, may result in slippage of a vertebrae. Degenerative forms are more likely to occur in women, persons older than fifty, and African-Americans.[2] • Traumatic spondylolisthesis is rare and results from acute fractures in the neural arch, other than the pars.[3] • Pathologic spondylolisthesis has been associated with damage to the posterior elements[which?] from metastases or metabolic bone disease. These slips have been reported in cases of Paget's disease of bone, tuberculosis, giant-cell tumors, and tumor metastases.[citation needed] • Dysplastic spondylolisthesis is a rare congenital spondylolisthesis occurring because of a malformation of thelumbosacral junction resulting in small, incompetent facet joints.

Lyme disease presenting as Tourette's syndrome Michael Riedel, Andreas Straube, Markus J Schwarz, Betina Wilske, Norbert Müller The Lancet, Vol. 351, No. 9100, February 1998 Lyme borreliosis is often misdiagnosed, both in adults and children.1 Central-nervous-system manifestations of Lyme disease include neurological and psychiatric symptoms.2 Although abnormal movements have have been observed in Lyme disease,3 a Tourette's syndrome has not been reported. A boy at the age of 4 years developed a simple motor tic (blinking) that resolved within a year without treatment. At the age of 9 years, he developed multiple orofacial tics including shaking of the head, and several weeks later a vocal tic occurred. The tics became exacerbated under stress, as typically seen in Tourette's syndrome. Social disabilities such as loss of impulse control, social withdrawal, and worsened performance at school followed. He came to hospital 11 months after onset of symptoms. Serum IgM antibody titres against Borrelia burgdorferi measured by ELISA were not increased; although IgG antibody titres (ELISA) were increased at 58 U/mL (normal 10 U/mL) and 100 U/mL at another examination 2 weeks later. Immunofluorescence absorption test (IFT) was also increased (1:128 [normal 1:16]). IgG immunoblot4 was positive. All results indicated an infection with B burgdorferi. Examination of the cerebral spinal fluid showed a slight lymphocytic pleocytosis (16 cells per µL), which suggested an inflammatory reaction. The CSF:serum lgG ratio for IgG antibodies was 2.0, indicating intrathecal production of B burgdorferi-specific IgG antibodies, as occurs in neuroborreliosis.4 The boy was treated with intravenous ceftriaxone 2 g daily for 14 days. The tics improved after the sixth dose, and after the tenth dose the tics resolved completely. His social skills returned to normal. Follow-up examinations showed no reccurrence of tics or other neurological or psychiatric disorder. Serum IgG antibody titres and IFT tests against B burgdorferi were 11 U/mL and 1:32 after 1 year. Rapid efficacy of antibiotic treatment followed by a decrease in Borrelia-specific antibody titres suggests that the multiple motor and vocal tics were at least partially caused by the tertiary stage of borreliosis.5 Persistence of the tics and increasing severity of the social disabilities over several months suggest that the first signs of a Tourette-like syndrome 11 months previously were an expression of an early Lyme infection. Infection with B burgdorferi should be considered in cases of Tourette's syndrome in endemic areas. 1 Shapiro ED, Selzter EG. Lyme disease in children. Semin Neurol 1997; 17: 39- 44.[PubMed]

2 Kaplan RF, Jones-Woodward L. Lyme encephalopathy: a neuropsychological perspective. Semin Neurol 1997; 17: 31-37. [PubMed]

3 Fallon BA, Nields JA, Parsons B, Liebowitz MR, Klein DF. Psychiatric manifestations of Lyme Borreliosis. J Clin Psychiatry 1997; 54: 263-68. [PubMed]

4 Wilske B, Fingerle V, Herzer P, et al. Recombinant immunoblot in the serodiagnosis of Lyme borreliosis. Med Mikrobiol Immunol 1993; 182: 255-70. [PubMed]

5 Pfister HW, Wilske B, Weber K. Lyme borreliosis: basic science and clinical aspects. Lancet 1994; 363: 1013-16 [PubMed

Psychiatric Hospital (N Müller), Department of Neurology, Klinikum Grosshadern, Ludwig- Maximilian-University, 81377 Munich, Germany; and Max-von-Pettenkofer Institute, München

Less Common Lyme Disease Associated Auto Immune System Diseases (Lyme bacteria present in all) These all have Peer Reviewed and Published Medical Research proving the connection 1. Abdominal wall weakness 2. Acrodermatitis chronica atrophicans (ACA) 3. Acute Acral Ischemia 4. Acute conduction disorders 5. Acute coronary syndrome 6. Acute exogenous psychosis 7. Acute febrile illness 8. Acute hemiparesis 9. Acute ischaemic pontine stroke 10. Acute meningitis 11. Acute myelo-meningo-radiculitis 12. Acute myelitis 13. Acute myopericarditis 14. Acute pediatric monoarticular arthritis 15. Acute peripheral facial palsy 16. Acute perimyocarditis 17. Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) 18. Acute pyogenic arthritis 19. Acute reversible diffuse conduction system disease 20. Acute septic arthritis 21. Acute severe encephalitis 22. Acute transitory auriculoventricular block 23. Acute transverse myelitis 24. Acute urinary retention 25. Acquired Immune Deficiency Syndrome (AIDS) 26. ADD/ ADHD 27. Algodystrophy 28. Allergic conditions 29. Allergic conjunctivitis 30. Alopecia 31. Amyotrophy 32. Anamnesis 33. Anetoderma 34. Aneurysm (some) 35. Anorexia nervosa 36. Anterior optic neuropathy 37. Antepartum fever 38. Anxiety 39. APS (antiphospholipid antibody syndrome) 40. Arrhythmia 41. Arthralgia 42. Asymmetrical hearing loss 43. Ataxic sensory neuropathy 44. Atraumatic spontaneous hemarthrosis 45. Atrioventricular block 46. Back pain without radiculitis 47. Bannwarth’s Syndrome 48. Behcet's disease 49. Bell’s Palsy 50. Benign cutaneous lymphocytoma 51. Benign lymphocytic infiltration (Jessner-Kanof) 52. Bilateral acute confluent disseminated choroiditis 53. Bilateral carpal tunnel syndrome 54. Bilateral facial nerve palsy 55. Bilateral follicular conjunctivitis 56. Bilateral keratitis 57. Bilateral papilloedema 58. Bilateral retrobulbar optic neuritis 59. Biphasic meningoencephalitis 60. Bipolar Disorder 61. Blau Syndrome (extenuating symptoms) 62. Brain Tumor 63. Brainstem tumor 64. Brown recluse spider bite 65. Brown-Sequard syndrome 66. CAID - Childhood Auto Inflammatory Disease 67. Cardiac abnormalities (mitral valve prolapse; myocarditis; tachycardia; palpitations; dysrhythmia) 68. Catatonic syndrome 69. Cauda equina syndrome 70. Central vestibular syndrome 71. Cerebellar ataxia 72. Cerebellitis 73. Cerebral atrophy 74. Cerebro-vascular disease 75. Cervical facet syndrome 76. Cheilitis granulomatosa 77. Chiasmal optic neuritis 78. Chorea 79. Choriocapillaritis 80. Cerebellar Ataxia Syndrome 81. Cancers (some) are infected with Borrelia burgdorferi 82. Celiac disease 83. Chronic inflammatory demyelinating polyneuropathy 84. Chronic recurrent multifocal osteomyelitis 85. Chronic urticaria 86. Cerebellar ataxia 87. Cogan’s syndrome 88. Collagenosis 89. Complete flaccid paraplegia 90. Concomitant neuroretinitis 91. Conduction disorder 92. Conus medullaris syndrome 93. Coronary aneurysm 94. Cortical blindness 95. Coxitis 96. Cranial Neuritis 97. Cranial polyneuritis 98. Craniopharyngioma 99. Crohn’s Disease 100. Cutaneous B-cell lymphoma 101. Cutaneous marginal-zone B-cell lymphoma 102. Cutaneous marginal zone lymphoma (SALT) 103. CVID - Common variable immunodeficiency 104. Dermatomyositis 105. Diaphragmatic paralysis 106. Diffuse fasciitis 107. Dilated cardiomyopathy 108. Diplopia 109. Discopathy 110. Disseminated choroiditis 111. Dorsal epiduritis 112. EDS - Ehlers-Danlos Syndrome (affects) 113. Endogenous paranoid-hallucinatory syndrome 114. Eosinophilia 115. Eosinophilic fasciitis (Shulman syndrome) 116. Epilepsy 117. Epileptic crises 118. Episcleritis 119. Exanthema (local and generalized) 120. Extrapyramidal disorders 121. Facial diplegia 122. Fascicular tachycardia 123. Fatal adult respiratory distress syndrome 124. Fetal death 125. Fibrositis 126. Focal nodular myositis 127. Frontotemporal atrophy 128. Generalised motor neuron disease 129. Geniculate neuralgia 130. Giant cell arteritis 131. Gonarthritis 132. Granuloma annulare 133. HLA-B27 negative sacroiliitis 134. Hallucinations (Painful) 135. Hemiparesis 136. Hemophagocytic syndrome 137. Hepatic disorders 138. Hepatitis 139. Herniated discs 140. Holmes-Adie syndrome 141. Horner's syndrome 142. Human necrotizing splenitis 143. Hydrocephalus 144. Hyperacusis 145. Hyperbilirubinemia 146. Idiopathic atrophoderma of Pasini and Pierini (IAPP) 147. Idiopathic facial paralysis 148. Infarction pain 149. Impaired Brainstem response 150. Infantile sclero-atrophic lichen 151. Infectious Mononucleosis 152. Infiltrating lymphadenosis benigna cutis 153. Inflammatory cerebrospinal fluid syndrome 154. Inflammatory choroidal neovascular membrane (CNVM) 155. Influenza 156. Internuclear ophthalmoplegia 157. Interstitial granulomatous dermatitis 158. Intracerebral haemorrhage 159. Intracranial aneurysm 160. Intracranial hypertension

161. Intracranial mass lesions 162. Intrauterine growth retardation 163. Iritis 164. Isolated posterior cord syndrome 165. Jaundice 166. Juvenile Rheumatoid Arthritis 167. Keratitis 168. Keratoconus 169. Kleine-Levin Syndrome 170. Leber's hereditary optic neuropathy 171. Left sided sudden hemiparesis 172. Leptospirosis 173. Leukemic meningeosis 174. Lichen sclerosus 175. Livedo racemosa 176. Lofgren's syndrome 177. Lumboabdominal pain 178. Lymphadenosis benigna cutis 179. Lymphocytoma cutis 180. Lumboradicular syndrome 181. Lymphocytic meningitis 182. Lymphoma 183. Madness 184. Melkersson-Rosenthal syndrome 185. Memory impairment 186. Meningeal lymphoma 187. Meningitis 188. Meningoencephalomyelitis 189. Meningoencephalomyeloradiculoneuritis 190. Meningopapillitis 191. Meningoradiculitis 192. Mesangioproliferative IgA-nephritis 193. Mono-arthritis 194. Monolateral chorioretinitis 195. Morgagni-Adams-Stokes syndrome (MAS) 196. Morning glory syndrome 197. Morphea 198. Motor neuron syndrome 199. Motoric disturbations 200. Multiple mononeuropathy 201. Multiple mononeuropathy and inflammatory syndrome 202. Musical hallucinations 203. Myelopathy 204. Myofascial pain syndrome 205. Myositis 206. Necrotizing granulomatous hepatitis 207. Neonatal respiratory distress 208. Neuromyotonia 209. Nodular fasciitis 210. Nodular panniculitis 211. Non-Hodgkin’s lymphoma 212. Normal-pressure hydrocephalus (NPH) 213. Obsessive-compulsive disorder 214. Ocular flutter 215. Oculomotor paralysis 216. Oligoarthritis 217. Opsoclonus-myoclonus syndrome 218. Optic atrophy 219. Optic disk edema 220. Orbital myositis 221. Organic mood syndrome 222. Optic nerve lesion 223. Otoneurological Disorders 224. Osteoarthritis 225. Osteoporosis 226. Panuveitis 227. Papillitis 228. Paralysis of abdominal muscles 229. Paralytic strabismus 230. Paraneoplastic polyneuropathy 231. Paranoia 232. Parotitis 233. Pars plana vitrectopy 234. Parry-Romberg syndrome 235. Parsonage and Turner syndrome 236. Patellar tendon rupture 237. Peripheral facial palsy 238. Peripheral neuropathy 239. Peripheral vascular disorder 240. Pericarditis 241. Perimyocarditis 242. Persistent atrioventricular block 243. Pigment epitheliitis 244. Pityriasis rosea 245. Pleural effusion 246. Polymyalgia rheumatica 247. Polyneuropathy/ Delaminating Neuropathy 248. Polyneuritis cranialis 249. Polyneuropathy 250. Polyradiculopathy 251. Polysymptomatic autoimmune disorder 252. Popliteal cyst 253. Porphyrinuria 254. Posterior scleritis 255. Postganglionic Horner syndrome 256. Primary lymphoma of the nervous system 257. Primary effusion lymphoma 258. Presenile dementia 259. Progressive cerebral infarction 260. Progressive facial hemiatrophy (Parry-Romberg syndrome) 261. Progressive stroke 262. Progressive supranuclear paralysis 263. Prolonged pyrexia 264. Propriospinal myoclonus 265. Pseudo-sepsis of the hip 266. Pseudo tumor Cerebrae 267. Pseudolymphoma 268. Pseudoneoplastic weight loss 269. Psychosomatic disorders 270. Primary lateral sclerosis 271. Pulmonary Fibrosis (chronic inflammatory processes) 272. Radiculalgia 273. Radiculoneuritis 274. Ramsay Hunt syndrome (pleocytosis) 275. Recurrent paralysis 276. Reflex sympathetic dystrophy 277. Reiter's Syndrome 278. Respiratory failure 279. Restless legs syndrome 280. Retinal pigment epithelium detachment 281. Retinal vasculitis 282. Reversible dementia 283. Rhombencephalitis 284. Rhombencephalomyelopathy 285. RSD - Reflex sympathetic dystrophy 286. Ruptured Baker cysts 287. Ruptured synovial cysts 288. Sacro-iliitis infection 289. SAPHO syndrome 290. Schizophrenia 291. Schoenlein-Henoch purpura 292. Secondary syphilis 293. Sensorineural Hearing Loss 294. Septal panniculitis 295. Septic arthritis 296. Seventh nerve paralysis 297. Sick sinus syndrome 298. Silent thalamic lesion 299. Somatic delusions 300. Spontaneous brain hemorrhage 301. Stevens-Johnson syndrome 302. Stiff-man syndrome 303. Still's disease 304. Stroke 305. Subacute Bacterial Endocarditis 306. Subacute multiple-site osteomyelitis 307. Subacute organic psychosyndrome 308. Subacute multiple-site osteomyelitis 309. Subacute presenile dementia 310. Subarachnoid hemorrhage 311. Sudden deafness 312. Sudden hemiparesis 313. Sudden infant death syndrome (SIDS) 314. Sudeck's atrophy 315. Synovitis 316. Syphilis 317. Symmetric Polyarthritis 318. Spondylosis 319. Temporal arteritis 320. Temporomandibular joint syndrome 321. Thrombocytopenic purpura 322. Transient Ischemic Attack 323. Transient left ventricular dysfunction 324. Transient synovitis 325. Trigeminal Neuralgia 326. Trigeminal palsy 327. Unilateral interstitial keratitis 328. Unilateral papillitis 329. Urticaria 330. Uveitis 331. Vasculitic neuropathy 332. Vasculitic mononeuritis multiplex 333. Vasculitis 334. Ventricular asystole 335. Vestibular neuronitis 336. Vitreous clouding 337. Vomiting (persistent) 338. Wegener's granulomatosis

Blood Transfusions, Donations, Supply and Lyme Disease

The Risk of Acquiring Lyme Disease or Babesiosis from a Blood Transfusion http://jid.oxfordjournals.org/content/170/1/231.short Borrelia burgdorferi: survival in experimentally infected human blood processed for transfusion http://www.samento.com.ec/science…/4lyme/bbinfectedhuman.htm Isolation of Borrelia burgdorferi from the blood of seven patients with Lyme disease http://www.amjmed.com/article/0002-9343(90)90122-T/abstract Lyme disease--another transfusion risk? http://onlinelibrary.wiley.com/…/j.1537- 2995.1989.…/abstract Transmission of tick-borne agents of disease by blood transfusion: a review of known and potential risks in the United States http://onlinelibrary.wiley.com/…/j.1537- 2995.2000.…/abstract Babesia Infection through Blood Transfusions: Reports Received by the US Food and Drug Administration, 1997–2007 http://cid.oxfordjournals.org/content/48/1/25.short Survival of Borrelia burgdorferi in blood products http://onlinelibrary.wiley.com/…/j.1537- 2995.1989.…/abstract

Yield of Large-Volume Blood Cultures in Patients with Early Lyme Disease http://jid.oxfordjournals.org/content/184/8/1070.short Transfusion transmitted infection: viral and exotic diseases http://europepmc.org/abstract/med/8447602 Survival of Borrelia burgdorferi in human blood stored under blood banking conditions http://onlinelibrary.wiley.com/…/j.1537-2995.1990.…/abstract Babesiosis and blood transfusion: flying under the radar http://onlinelibrary.wiley.com/…/j.1423-0410.2006…/abstract… Risk and prevention of transfusion-transmitted babesiosis and other tick-borne diseases http://journals.lww.com/…/Risk_and_prevention_of_transfusio… Emerging Infectious Diseases That Threaten the Blood Supply http://www.seminhematol.org/…/S0037-1963(06)00238-1/abstract Risks of blood transfusion http://journals.lww.com/…/12001/Risks_of_blood_transfusion.… A Cluster of Transfusion-Associated Babesiosis Cases Traced to a Single Asymptomatic Donor http://jama.jamanetwork.com/article.aspx?articleid=189030 Transfusion-transmitted babesiosis: a case report from a new endemic area http://onlinelibrary.wiley.com/…/j.1537-2995.1991…/abstract… Emerging Infectious Agents: Do They Pose a Risk to the Safety of Transfused Blood and Blood Products? http://cid.oxfordjournals.org/content/34/6/797.short Blood Transfusion in Contemporary Obstetric Practice http://journals.lww.com/…/Blood_Transfusion_in_Contemporary… Borrelia burgdorferi: Survival in Experimentally Infected Human Blood Processed for Transfusion http://jid.oxfordjournals.org/content/162/2/557.short Risks associated with transfusion of cellular blood components in Canada http://www.sciencedirect.com/…/article/pii/S0887796303900034 Emerging Infectious Threats to the Blood Supply http://www.annualreviews.org/…/10.1146/annurev.med.55.09190… Transmission of Parasites by Blood Transfusion http://onlinelibrary.wiley.com/…/j.1423- 0410.1998.…/abstract Perinatal Transmission of the Agent of Human Granulocytic Ehrlichiosis http://www.nejm.org/doi/full/10.1056/nejm199808063390604 Transfusion-Acquired, Autochthonous Human Babesiosis in Japan: Isolation of Babesia microti-Like Parasites with hu-RBC-SCID Mice http://jcm.asm.org/content/38/12/4511.short The United States' potential blood donor pool: estimating the prevalence of donor-exclusion factors on the pool of potential donors http://onlinelibrary.wiley.com/…/j.1537- 2995.2007…/abstract… Babesiosis Acquired through Blood Transfusion, California, USA http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687036/ Transfusion-associated transmission of babesiosis in New York State http://onlinelibrary.wiley.com/…/j.1537-2995.2000…/abstract… Emerging infectious disease agents and their potential threat to transfusion safety http://onlinelibrary.wiley.com/…/j.1537-2995.2009.…/abstract Demonstrable parasitemia among Connecticut blood donors with antibodies to Babesia microti http://onlinelibrary.wiley.com/…/j.1537-2995.2005.…/abstract Transfusion-transmitted babesiosis in Ontario: first reported case in Canada http://www.cmaj.ca/content/164/12/1721.short Laboratory Diagnosis of Infections Due to Blood and Tissue Parasites http://cid.oxfordjournals.org/content/49/7/1103.short Safety of the Blood Supply http://journals.lww.com/…/12000/Safety_of_the_Blood_Supply.… An investigation into the possibility of transmission of tick-borne pathogens via blood transfusion http://onlinelibrary.wiley.com/…/j.1537-2995.1999…/abstract… A Lyme Borreliosis Human Serosurvey of Asymptomatic Adults in Ireland http://www.sciencedirect.com/…/article/pii/S093488401180304X Transfusion-Transmitted Babesia spp.: Bull's-Eye on Babesia microti http://cmr.asm.org/content/24/1/14.short A short-term Borrelia burgdorferi infection model identifies tissue tropisms and bloodstream survival conferred by adhesion proteins http://www.prohealth.com/library/showarticle.cfm?libid=20610 Tick-borne infection appearing in blood supply http://m.nydailynews.com/…/u-s-blood- supply-plays-host-tick… A New Tick-Borne Parasite That Invades Red Blood Cells: Beware Babesiosis http://www.forbes.com/…/its-tick-season-beware-this-new-ti…/ Hospitals Knowingly Dispense Poisoned Blood http://www.thedailybeast.com/…/hospitals- knowingly-dispense… FDA looks at Babesia blood donor screening http://outbreaknewstoday.com/fda-looks-at- babesia-blood-do…/

Chronic Lyme Disease Proof That Chronic Lyme Disease Exists (but you can still get completely well and be symptom free) http://www.hindawi.com/journals/ipid/2010/876450/ Persistence of Immunoglobulin M or Immunoglobulin G Antibody Responses toBorrelia burgdorferi 10–20 Years after Active Lyme Disease http://cid.oxfordjournals.org/content/33/6/780.short Identification of candidate T-cell epitopes and molecular mimics in chronic Lyme disease http://www.nature.com/nm/journal/v5/n12/abs/nm1299_1375.html Two Controlled Trials of Antibiotic Treatment in Patients with Persistent Symptoms and a History of Lyme Disease http://www.nejm.org/doi/full/10.1056/NEJM200107123450202 Tetracycline Therapy for Chronic Lyme Disease http://cid.oxfordjournals.org/cont…/…/Supplement_1/S52.short Chronic Neurologic Manifestations of Lyme Disease http://www.nejm.org/doi/full/10.1056/nejm199011223232102

Chronic Lyme Disease http://www.sciencedirect.com/…/article/pii/S0891552015000203

Chronic Lyme Disease: A Review Infectious Disease Clinics of North America Volume 22, Issue 2, June 2008, Pages 341–360 Tick-borne Diseases, Part I: Lyme Disease http://www.sciencedirect.com/…/article/pii/S0891552007001274

Chronic lyme disease in the rhesus monkey http://europepmc.org/abstract/med/7853849 The triad of neurologic manifestations of Lyme disease: Meningitis, cranial neuritis, and radiculoneuritis http://www.neurology.org/content/35/1/47.short Spirochetes Isolated from the Blood of Two Patients with Lyme Disease http://www.nejm.org/doi/pdf/10.1056/NEJM198303313081302 Therapeutic passive vaccination against chronic Lyme disease in mice http://www.pnas.org/content/94/23/12533.short Association of chronic Lyme arthritis with HLA-DR4 and HLA-DR2 alleles http://www.nejm.org/doi/pdf/10.1056/NEJM199007263230402 Association of treatment-resistant chronic Lyme arthritis with HLA-DR4 and antibody reactivity to OspA and OspB of Borrelia burgdorferi http://iai.asm.org/content/61/7/2774.short Controlled Trials of Antibiotic Treatment in Patients with Post-Treatment Chronic Lyme Disease http://online.liebertpub.com/…/a…/10.1089/153036602321653842 A proposal for the reliable culture ofBorrelia burgdorferi from patients with chronic lyme disease, even from those previously aggressively treated http://link.springer.com/article/10.1007/BF02770837 The emergence of Lyme disease http://www.ncbi.nlm.nih.gov/pmc/articles/PMC385417/ TREATMENT OF LATE LYME BORRELIOSIS—RANDOMISED COMPARISON OF CEFTRIAXONE AND http://www.sciencedirect.com/…/article/pii/S0140673688920119 Lyme disease: an infectious and postinfectious syndrome http://europepmc.org/abstract/med/8006888 Musculoskeletal manifestations of Lyme disease http://www.sciencedirect.com/…/article/pii/S0002934399800436 Borrelia burgdorferi DNA in the urine of treated patients with chronic lyme disease symptoms. A PCR study of 97 cases http://link.springer.com/article/10.1007/BF01716077 Chronic Lyme Arthritis: Clinical and Immunogenetic Differentiation from Rheumatoid Arthritis http://annals.org/article.aspx?articleid=693095 Lyme Carditis: Cardiac Abnormalities of Lyme Disease http://annals.org/article.aspx?articleid=694150 Psychiatric Comorbidity and Other Psychological Factors in Patients with Chronic Lyme Disease http://www.sciencedirect.com/…/article/pii/S0002934309003428 Ecology of Ixodes Dammini-Borne Human Babesiosis and Lyme Disease http://www.annualreviews.org/…/10.1146/annurev.en.30.010185… Spirochetes in the spleen of a patient with chronic Lyme disease http://europepmc.org/abstract/med/2910019 The Long-Term Clinical Outcomes of Lyme Disease: A Population-Based Retrospective Cohort Study http://annals.org/article.aspx?articleid=708078 Contributions of societal and geographical environments to "chronic Lyme disease": the psychopathogenesis and aporology of a new "medically unexplained symptoms" syndrome http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241213/ Isolation and characterization of the Lyme disease spirochete from the skin of patients with erythema chronicum migrans http://www.sciencedirect.com/…/article/pii/S0190962285701879 Late and chronic Lyme disease http://www.sciencedirect.com/…/article/pii/S0025712503000907 Longterm decrease in the CD57 lymphocyte subset in a patient with chronic Lyme disease http://europepmc.org/abstract/med/12088407 Borrelia burgdorferi in Joint Fluid in Chronic Lyme Arthritis http://annals.org/article.aspx?articleid=700495 Neuro-Ophthalmologic Manifestations of Lyme Disease http://www.sciencedirect.com/…/article/pii/S0161642090325198 Psychological States and Neuropsychological Performances in Chronic Lyme Disease http://www.tandfonline.com/d…/abs/10.1207/s15324826an0601_3… A Controlled Study of Cognitive Deficits in Children With Chronic Lyme Disease http://neuro.psychiatryonline.org/…/abs/10.1176/jnp.13.4.500 Role of psychiatric comorbidity in chronic Lyme disease http://onlinelibrary.wiley.com/doi/10.1002/art.24314/full Regional Cerebral Blood Flow and Cognitive Deficits in Chronic Lyme Disease http://neuro.psychiatryonline.org/…/abs/10.1176/jnp.15.3.326 Borrelia burgdorferi persists in the brain in chronic lyme neuroborreliosis and may be associated with Alzheimer disease http://www.lymeeducation.com/reference_doc…/bb_alzheimer.pdf Peripheral nervous system Lyme borreliosis http://europepmc.org/abstract/med/9166956 Clinical Pathologic Correlations of Lyme Disease http://cid.oxfordjournals.org/co…/…/Supplement_6/S1487.short Posttreatment Chronic Lyme Disease—What It Is Not http://jid.oxfordjournals.org/content/192/6/948.short

Mycoplasma, the Most Common Lyme Coinfection https://vitalplan.com/blog/mycoplasma-the-most-common-lyme-coinfection 1. K Waites and D Talkington, Mycoplasma pneumoniae and its Role as a Human Pathogen, Oct 2004, Clinical Microbiology Reviews 2. Hakkarainen, Turrunen, Miettinen, Kaitik, and Jannson, Mycoplasmas and Arthritis, Ann Rheu Dis, 1992, Oct 5 (11): p. 1170-1172 3. Baseman, Joel, et.al., Mycoplasmas: Sophisticated, Reemerging, and Burdened by Their Notoriety, CDC, Journal of Infectious Diseases, Vol 3, No.1, Feb 1997 4. Leslie Taylor, ND, Mycoplasmas – Stealth Pathogens (Review article), Jan 2001 5. Razin, Yogev, Naot, Molecular Biology and Pathogenicity of Mycoplasmas, Microbiol Mol Biol Rev, 1998, Dec; 62(4): p. 1094-1156 6. J Rivera-Tapia, N Rodriguez-Preval, Possible role of mycoplasmas in pathogenesis of gastrointestinal diseases, Rev Biomed 2006 17: 132-139 7. Berghoff, W, Chronic Lyme Disease and Co-infections: Differential Diagnosis, Open Neurol J., 2012, 6, p. 158-178 8. Gilroy, Keat, Taylor-Robinson, The Prevalence of Mycoplasma fermentans in patients with arthritides, Rheumatology, Vol 40 (12), p. 1355-1358 9. Zhang et al, Mycoplasma fermentans infection promotes immortalization of human peripheral blood mononuclear cells in culture, Blood 104 (13), p. 4252-4259 10. Walter Berghoff, Chronic Lyme Disease and Co-infections: Differential Diagnosis, Open Neurol J, 2012, 6: p. 158-178 11. Buhner S H, Healing Lyme Disease Coinfections, Healing Arts Press, Copyright 2013 12. http://www.cdc.gov/pneumonia/atypical/mycoplasma/index.html

Bartonella: Coinfection of Lyme Disease Emerging or re-emerging bacterial zoonotic diseases: bartonellosis, leptospirosis, Lyme borreliosis, plague http://europepmc.org/abstract/med/15702720 Bartonella spp. Bacteremia and Rheumatic Symptoms in Patients from Lyme Disease–endemic Region http://wwwnc.cdc.gov/eid/article/18/5/11-1366_article… Emerging incidence of Lyme borreliosis, babesiosis, bartonellosis, and granulocytic ehrlichiosis in Australia http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258014/ Prevalence of Borrelia burgdorferi, Bartonella spp., Babesia microti, and Anaplasma phagocytophila in Ixodes scapularis Ticks Collected in Northern New Jersey http://jcm.asm.org/content/42/6/2799.short Evidence of Bartonella sp. in questing adult and nymphal Ixodes ricinus ticks from France and co- infection with Borrelia burgdorferi sensu lato and Babesia sp. L Halos, T Jamal, R Maillard, F Beugnet… - Veterinary …, 2005 - sfo.edpsciences.org ... This study confirms the fact that the coex- istence of Bartonella sp. and/or Babesia sp. ... REFERENCES [1] Alexander B., A review of bartonellosis in Ecuador and Colombia, Am. ... 52 (1995) 354–359. [2] Barthold SW, Globalisation of Lyme borre- liosis, Lancet 348 (1996) 1603. Concurrent Infection of the Central Nervous System by Borrelia burgdorferi and Bartonella henselae http://archneur.jamanetwork.com/article.aspx… Bartonella henselae and Borrelia burgdorferi Infections of the Central Nervous System http://onlinelibrary.wiley.com/…/j.1749-6632.2003…/abstract… Bartonella spp. Bacteremia and rheumatic symptoms in patients from lyme disease-endemic region http://europepmc.org/abstract/med/23251952 Prevalence of Bartonella henselae and Borrelia burgdorferi Sensu Lato DNA in Ixodes ricinus Ticks in Europe▿ http://aem.asm.org/content/76/5/1395.short Bartonella spp. Bacteremia and Rheumatic Symptoms in Patients from Lyme Disease–endemic Region http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559143/ Cosegregation of a Novel Bartonella Species with Borrelia burgdorferi and Babesia microti in Peromyscus leucopus http://jid.oxfordjournals.org/content/177/2/409.short Serological survey in persons occupationally exposed to tick-borne pathogens in cases of co- infections with Borrelia burgdorferi, Anaplasma phagocytophilum, Bartonella spp. and Babesia microti http://yadda.icm.edu.pl/…/bwmeta1.element.agro-002af568-604… Vector-Borne and Zoonotic Diseases http://online.liebertpub.com/doi/abs/10.1089/vbz.2008.0005 Bartonella quintana invades and multiplies within endothelial cellsin vitro and in vivo and forms intracellular blebs http://www.sciencedirect.com/…/article/pii/S0923250897851194 Molecular Evidence of Bartonella spp. in Questing Adult Ixodes pacificus Ticks in California http://jcm.asm.org/content/39/4/1221.short Chronic Coinfections in Patients Diagnosed with Chronic Lyme Disease: A Systematic Review http://www.sciencedirect.com/…/article/pii/S0002934314004768 Clinical determinants of Lyme borreliosis, babesiosis, bartonellosis, anaplasmosis, and ehrlichiosis in an Australian cohort http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278782/ Bartonella, A Chronic Lyme Disease Coinfection, is More Causing Chronic Fatigue Problems http://www.envita.com/…/chronic-lyme-disease-coinfection-ba… Bartonella Introduction http://www.lymedisease.org/lym…/coinfections/bartonella.html Bartonella, a Stealth Infection http://www.nutritionalhealthnow.com/bartonella-a-stealth-i…/ BARTONELLA ALERT http://www.lymeinfo.net/bartonella.html Bartonella: A New Frontier in Chronic Disease http://lymehandbook.com/…/bartonella-a-new-frontier- in-chr…/ What is Lyme Disease? http://whatislyme.com/bartonella/ Bartonellosis (AKA Bartonella Illness) http://www.lymediseaseassociation.org/…/other…/bartonellosis Chronic Lyme Disease and Co-infections: Differential Diagnosis http://www.lymediseaseassociation.org/…/other…/bartonellosis LYME DISEASE COINFECTIONS http://www.lymeinfo.net/coinfections.html Lyme disease and bartonellosis http://www.benbrew.com/lb/lb.html Lyme Disease and Bartonella: More Common Than You Think http://suzycohen.com/…/lyme-disease- and-bartonella-more-co…/ Bartonellosis - Bartonella zoonotic infections http://www.lyme-symptoms.com/CoInfectionsBartonellas.html Uncovering the 'Stealth Pathogen' http://www.cvm.ncsu.edu/…/2012-05-04-Uncovering-Bartonella-… Bartonella spp. Bacteremia and Rheumatic Symptoms in Patients from Lyme Disease–endemic Region http://wwwnc.cdc.gov/eid/article/18/5/pdfs/11-1366.pdf Buhner Healing Lyme http://www.buhnerhealinglyme.com/…/co-infections/bartonella/ A Serious Disease With Potentially Serious Consequences https://sites.google.com/…/m…/tick-borne- diseases/bartonella BARTONELLA LIKE ORGANISMS (BLO): CONSIDERATION, SIGNS AND SYMPTOMS http://www.gordonmedical.com/…/bartonella-like-organisms-b…/ Co-infection symptoms & Lyme symptoms http://www.truthaboutlymedisease.com/phpBB3/viewtopic.php… Co-Infection Introduction http://www.lymedisease.org/ly…/coinfections/coinfection.html Richard Horowitz, MD (Lyme-MSIDS(Ques5onnaire http://healthspaceclinics.com.au/…/7.%20Symptom%20and%20Dia… BARTONELLA ALERT http://www.lymeinfo.net/bartonella.html

Mosquitoes Transmit Lyme Disease: The Proof

Selected phenotypic features of BR91, a unique spirochaetal strain isolated from the Culex pipiens mosquito http://www.sciencedirect.com/…/article/pii/S0944501313001717 Proven - Lyme Disease Is Spread By Mites, Spiders, Mosquitoes, Fleas It Is Also Spread Via ALL Body Fluids http://www.rense.com/general94/provenlym.htm Lyme Disease and Newburyport Tick Control https://mosquitosquadnorthshore.wordpress.com/ New Ideas About the Cause, Spread and Therapy of Lyme Disease http://www.samento.com.ec/science…/4lyme/Townsendhowens.html Ticks and biting insects infected with the etiologic agent of Lyme disease, Borrelia burgdorferi http://jcm.asm.org/content/26/8/1482.short The Etiologic Agent of Lyme Disease in Deer Flies, Horse Flies, and Mosquitoes http://www.jstor.org/stable/30105775… Experimental Infections of Mosquitoes with Borrelia burgdorferi, the Etiologic Agent of Lyme Disease http://jid.oxfordjournals.org/content/156/4/694.short Birds, Migration and Emerging Zoonoses: West Nile Virus, Lyme Disease, Influenza A and Enteropathogens http://www.clinmedres.org/content/1/1/5.short Resurgent vector-borne diseases as a global health problem http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640300/ Dissemination and Salivary Delivery of Lyme Disease Spirochetes in Vector Ticks (Acari: Ixodidae) http://jme.oxfordjournals.org/content/24/2/201 The Global Distribution of Lyme Disease http://cid.oxfordjournals.org/content/7/1/41.short Spatial epidemiology: an emerging (or re-emerging) discipline http://www.sciencedirect.com/…/article/pii/S0169534705000716 Intrinsic Competence of Three Ixodid Ticks (Acari) as Vectors of the Lyme Disease Spirochete http://jme.oxfordjournals.org/content/27/4/646 Spatial Analysis of the Distribution of Lyme Disease in Wisconsin http://aje.oxfordjournals.org/content/145/6/558.short Vectors vs. humans in Australia--who is on top down under? An update on vector-borne disease and research on vectors in Australia http://europepmc.org/abstract/med/9673928 Discovery of the Lyme disease spirochete and its relation to tick vectors http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2590008/ Risk Maps: Transmission and Burden of Vector-borne Diseases http://www.sciencedirect.com/…/article/pii/S0169475800017087 Diagnosis and Treatment of Lyme Disease http://www.sciencedirect.com/…/article/pii/S0025619611607313 Isolation of Borrelia afzelii from Overwintering Culex pipiens Biotype molestus Mosquitoes http://link.springer.com/article/10.1007/s150100050029

If antibiotics worked to solve late stage Lyme disease, why is the problem not eliminated? Here are the proven medical reasons:

Antibiotics Are Proven Not To Work on Chronic Lyme Disease Chronic Persistent Infection with Bp Despite Intensive Antibiotics The persistence of spirochetal nucleic acids in active Lyme arthritis http://www.ncbi.nlm.nih.gov/pubmed/8093136 Chronic Persistent Lyme Borreliosis: PCR Evidence of Chronic Infection Despite Extended Antibiotic Therapy—A Retrospective Review http://www.northamptonwellness.com/…/Chronic-Persistent-Lym… Survival of Borrelia burgdorferi in antibiotically treated patients with Lyme borreliosis http://www.ncbi.nlm.nih.gov/pubmed/2613324 Molecular detection of persistent Borrelia burgdorferi in the urine of patients with active Lyme disease http://aac.asm.org/content/52/5/1728.short Borrelia burgdorferi DNA in the urine of treated patients with chronic Lyme disease symptoms. A PCR study of 97 cases http://www.ncbi.nlm.nih.gov/pubmed/8923044 Lyme meningoencephalitis: report of a severe, penicillin-resistant case http://www.ncbi.nlm.nih.gov/pubmed/3649235 Chronic septic arthritis caused by Borrelia burgdorferi http://www.ncbi.nlm.nih.gov/pubmed/8242938 Tetracycline therapy for chronic Lyme disease http://www.ncbi.nlm.nih.gov/pubmed/9233665 Fibroblasts protect the Lyme disease spirochete, Borrelia burgdorferi, from ceftriaxone in vitro http://www.ncbi.nlm.nih.gov/pubmed/1634816 Molecular detection of persistent Borrelia burgdorferi in a man with dermatomyositis http://europepmc.org/abstract/med/1395222 Borrelia Burgdorferi Persists in the Gastrointestinal Tract of Children and Adolescents with Lyme Disease http://www.healthydays.info/borrelia-burgdorferi-persists-i… Long-term follow-up of chronic Lyme neuroretinitis http://www.ncbi.nlm.nih.gov/pubmed/9002133 PCR detection of Borrelia burgdorferi DNA in cerebrospinal fluid of Lyme neuroborreliosis patients http://www.ncbi.nlm.nih.gov/pubmed/1734321 Detection of Borrelia burgdorferi DNA in urine samples and cerebrospinal fluid samples from patients with early and late Lyme neuroborreliosis by polymerase chain reaction http://www.ncbi.nlm.nih.gov/pmc/articles/PMC265358/ Cultivation of Borrelia burgdorferi from joint fluid three months after treatment of facial palsy due to Lyme borreliosis http://www.ncbi.nlm.nih.gov/pubmed/3171237 Intracellular persistence of Borrelia burgdorferi in human synovial cells http://link.springer.com/article/10.1007/BF01409985 Pulsed high-dose cefotaxime therapy in refractory Lyme borreliosis http://www.ncbi.nlm.nih.gov/pubmed/1677097 Persistence of Borrelia burgdorferi in ligamentous tissue from a patient with chronic Lyme borreliosis http://www.ncbi.nlm.nih.gov/pubmed/8240439 Persistence of Borrelia burgdorferi in ligamentous tissue from a patient with chronic Lyme borreliosis http://www.ncbi.nlm.nih.gov/pubmed/8240439 In vitro and in vivo susceptibility of the Lyme disease spirochete, Borrelia burgdorferi, to four antimicrobial agents http://www.ncbi.nlm.nih.gov/pubmed/3566246 Evidence-based guidelines for the management of Lyme disease http://informahealthcare.com/d…/abs/10.1586/14789072.2.1.S1… Dermatomyositis Associated with Lyme Disease: Case Report and Review of Lyme Myositis http://cid.oxfordjournals.org/content/18/2/166.short Persistence of Borrelia burgdorferi following Antibiotic Treatment in Mice http://aac.asm.org/content/52/5/1728.short Evidence of Persistent Infection http://www.lymedisease.org/reso…/persistence%20confirmed.pdf Intracellular localization of Borrelia burgdorferi within human endothelial cells http://www.ncbi.nlm.nih.gov/pmc/articles/PMC257809/ Chronic septic arthritis caused by Borrelia burgdorferi http://www.ncbi.nlm.nih.gov/pubmed/8242938 Pars plana vitrectomy in Borrelia burgdorferi endophthalmitis http://www.ncbi.nlm.nih.gov/pubmed/10048013 Persistence of Borrelia burgdorferi and histopathological alterations in experimentally infected animals. A comparison with histopathological findings in human Lyme disease http://www.ncbi.nlm.nih.gov/pubmed/2076905 PCR-Based Quantification of Borrelia burgdorferi Organisms in Canine Tissues over a 500- Day Post infection Period http://jcm.asm.org/content/38/6/2191.short Ineffectiveness of Tigecycline against Persistent Borrelia burgdorferi http://aac.asm.org/content/54/2/643.short Persistence of Borrelia burgdorferi in Rhesus Macaques following Antibiotic Treatment of Disseminated Infection http://journals.plos.org/plosone/article… Richard Horowitz, LLMD https://www.youtube.com/watch?v=SXxWxMuUh8w&feature=youtu.be Seronegative chronic relapsing neuroborreliosis http://www.ncbi.nlm.nih.gov/pubmed/7796837 Detection of Borrelia burgdorferi DNA by Polymerase Chain Reaction in Synovial Fluid from Patients with Lyme Arthritis http://www.nejm.org/doi/full/10.1056/NEJM199401273300401 Formation and cultivation of Borrelia burgdorferi spheroplast-L-form variants http://www.ncbi.nlm.nih.gov/pubmed/8811359 Borrelia burgdorferi detected by culture and PCR in clinical relapse of disseminated Lyme borreliosis http://www.ncbi.nlm.nih.gov/pubmed/10442678?dopt=Citation Two controlled trials of antibiotic treatment in patients with persistent symptoms and a history of Lyme disease http://www.ncbi.nlm.nih.gov/pubmed/11450676?dopt=Citation Study and treatment of post Lyme disease (STOP-LD): a randomized double masked clinical trial http://www.ncbi.nlm.nih.gov/pubmed/12821734?dopt=Citation Randomized Comparison of Ceftriaxone and Cefotaxime in Lyme Neuroborreliosis http://jid.oxfordjournals.org/content/163/2/311.short Detection of Borrelia burgdorferi by polymerase chain reaction in synovial membrane, but not in synovial fluid from patients with persisting Lyme arthritis after antibiotic therapy http://ard.bmj.com/content/57/2/118 Cultivation and characterization of spirochetes from cerebrospinal fluid of patients with Lyme borreliosis http://www.ncbi.nlm.nih.gov/pmc/articles/PMC269647/ Cultivation of Borrelia burgdorferi from joint fluid three months after treatment of facial palsy due to Lyme borreliosis J. Infect Dis 158 (1988) 905-906 http://www.borrelioosi.net/foorumi/viewtopic.php?t=48&p=9496

Persistence of Borrelia burgdorferi following antibiotic treatment in mice http://www.ncbi.nlm.nih.gov/pubmed/18316520 Chronic Lyme Disease: An appraisal http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430045/ Lyme disease: A Look Beyond Antibiotics Dietrich K.Klinghardt, MD, PhD http://www.klinghardtacademy.com/…/…/Lyme_protocol_Jan06.pdf