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COVID-19 mRNA Vaccine 3rd Dose Eligibility Immunosuppressing Medications

Updated: August 16, 2021

Examples of medication that typically are immunosuppressing include: • (Orencia) • (arava) • (Humira) • (Tysabri) • (Lemtrada) within the past • Prednisone or equivalent >= 20mg/day 3 years • • Alkylating agents inc. • Mycophenolate • (Kineret) mofetil (Myfortic, Cellcept) • Antimetabolites • 6-mercaptopurine • (imuran) • Natalizumab (Tysabri) • Baracitinib (Olumiant) • (Ocrevus) • (Benlysta) • Ofatumumab (Kesimpta) • Brodalumab (Siliq) • (Zeposia) • Canakinumab (Ilaris) • (Ponvory) • Cancer chemotherapeutic • Risankizumab (Skyrizi) agents classified • (Rituxan, rituximab- as severely immunosuppressive arrx, truxima) • Certolizumab (Cimzia) • Sartralizumab (Enspryng) • Clabdribine (Mavneclad) within the past 2 • (Cosentyx) years • (Mayzent) • Cyclophosphamide (Cytoxan) • • Cyclosporine • (Aubagio) • Patients on cytotoxic chemotherapy • Tildrakizumab (Ilumya) within the last 6 months or other anti- • (Actemra) cancer therapies that are known to be • (Xeljanz) moderately or severely • Transplant-related immunosuppressive immunosuppressive drugs • (Tecfidera) • Tremfya • Diroximel fumarate (Vumerity) • Sarilumab (Kevzara) • (Soliris) • Upadacitinib (Rinvoq) • (Enbrel) • (Stelara) • (Gilenya) • (Entyvio) • (Simponi) • Voclosporin (Lupkynis) • Guselkumab (Tremfya) • TNF Blockers • Inebilizumab (Uplizna) • Other biologic agents that are • (Remicade, Inflectra, Renflexis) immunosuppressive or • Intravenous immunoglobulin (IVIG) immunomodulatory • Ixekizumab (Talz)

Examples of medication that typically are NOT immunosuppressing include the following. Please talk to your doctor about these: • (Otezla) • Glatiramer acetate (Copaxone, Glatopa) • Hydroxychloroquine (Plaquenil) • beta medications (Avonex, Rebif, Betaseron, Extavia, Plegridy) • Sulfasalazine (Azulfidine)

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