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Copyright ©2017 Innovative Medicines Initiative Prepared by Clarivate Analytics on behalf of IMI Programme Office under a public procurement procedure document reference: Bibliometric analysis of IMI ongoing projects IMI2/INT/2015-01848 1 Disclaimer/Legal Notice This document has been prepared solely for the Innovative Medicines Initiative (IMI). All contents may not be re-used (in whatever form and by whatever medium) by any third party without prior permission of the IMI. Bibliom etric analysis of IMI ongoing projects 2 Table of Contents 1 EXECUTIVE SUMMARY ................................................................................................................. 5 2 INTRODUCTION ............................................................................................................................. 8 2.1 OVERVIEW ............................................................................................................................. 8 2.2 INNOVATIVE MEDICINES INITIATIVE (IMI) JOINT UNDERTAKING ................................... 8 2.3 CLARIVATE ANALYTICS ....................................................................................................... 8 2.4 SCOPE OF THIS REPORT .................................................................................................... 9 3 DATA SOURCES, INDICATORS AND INTERPRETATION ......................................................... 10 3.1 BIBLIOMETRICS AND CITATION ANALYSIS ..................................................................... 10 3.2 DATA SOURCE .................................................................................................................... 10 3.3 METHODOLOGY .................................................................................................................. 11 3.4 DATA COLLATION ............................................................................................................... 12 4 CITATION ANALYSIS – IMI SUPPORTED PUBLICAITONS OVERALL ...................................... 13 4.1 PUBLICATIONS FROM IMI-SUPPORTED PROJECTS ...................................................... 13 4.2 SHARE OF PAPERS RELATIVE TO OTHER PUBLICATION TYPES ................................ 15 4.3 TRENDS IN PUBLICATION OUTPUT .................................................................................. 16 4.4 IN WHICH JOURNALS DO IMI PROJECT PUBLICATIONS APPEAR MOST FREQUENTLY? ................................................................................................................................ 18 4.5 WHICH RESEARCH FIELDS ACCOUNT FOR THE HIGHEST VOLUME OF IMI PROJECT PUBLICATIONS? .............................................................................................................................. 22 4.6 IMI RESEARCH FIELDS WITH HIGHEST VOLUME OF PUBLICATIONS BENCHMARKED AGAINST EU-28 PUBLICATIONS OF THE SAME FIELD ............................................................... 25 4.7 IS IMI PROJECT RESEARCH WELL-CITED? ..................................................................... 26 5 CITATION ANLYSIS – AT IMI PROJECT LEVEL ......................................................................... 27 5.1 TRENDS IN PUBLICATION OUTPUT BY IMI FUNDING CALL .......................................... 27 5.2 SUMMARY BIBLIOMETRIC ANALYSES FOR IMI PROJECTS – CALL 1 .......................... 29 5.3 SUMMARY BIBLIOMETRIC ANALYSES FOR IMI PROJECTS – CALL 2 .......................... 31 5.4 SUMMARY BIBLIOMETRIC ANALYSES FOR IMI PROJECTS – CALL 3 .......................... 33 5.5 SUMMARY BIBLIOMETRIC ANALYSES FOR IMI PROJECTS – CALL 4 .......................... 35 5.6 SUMMARY BIBLIOMETRIC ANALYSES FOR IMI PROJECTS – CALL 5-11 ..................... 37 5.7 SUMMARY BIBLIOMETRIC ANALYSES FOR IMI 2 PROJECTS ....................................... 40 6 COLLABORATION ANALYSIS FOR IMI RESEARCH .................................................................. 42 6.1 COLLABORATION ANALYSIS FOR IMI RESEARCH ......................................................... 42 6.2 COLLABORATION ANALYSIS BY IMI PROJECT ............................................................... 43 6.3 COLLABORATION METRICS FOR IMI RESEARCH........................................................... 53 6.3.1 METRIC 1: FRACTION OF CROSS SECTOR COLLABORATIVE PUBLICATIONS ...... 54 6.3.2 METRIC 2: FRACTION OF INTERNATIONALLY COLLABORATIVE PUBLICATIONS .. 55 Bibliom etric analysis of IMI ongoing projects 3 6.3.3 METRIC 3: TOP COLLABORATING ORGANISATIONS PER PUBLICATION................ 56 6.4 COLLABORATION INDEX .................................................................................................... 59 7 BENCHMARKING ANALYSIS – IMI PROJECT RESEARCH AGAINST RESEARCH FROM SELECTED COMPARATORS .............................................................................................................. 60 7.1 IDENTIFYING COMPARATORS .......................................................................................... 60 7.2 TRENDS IN OUTPUT: IMI PROJECT RESEARCH COMPARED WITH SELECTED COMPARATORS .............................................................................................................................. 61 7.2.1 TRENDS IN OUTPUT: IMI PROJECT RESEARCH COMPARED WITH SELECTED COMPARATORS ........................................................................................................................... 61 7.2.2 TRENDS IN FIELD NORMALISED CITATION IMPACT: IMI PROJECT RESEARCH COMPARED WITH SELECTED COMPARATORS ...................................................................... 63 7.2.3 TRENDS IN JOURNAL NORMALISED CITATION IMPACT: IMI PROJECT RESEARCH COMPARED WITH SELECTED COMPARATORS ...................................................................... 65 7.2.4 TRENDS IN RAW CITATION IMPACT: IMI PROJECT RESEARCH COMPARED WITH SELECTED COMPARATORS ....................................................................................................... 66 7.2.5 TRENDS IN UNCITED RESEARCH: IMI PROJECT RESEARCH COMPARED WITH SELECTED COMPARATORS ....................................................................................................... 67 7.2.6 TRENDS IN HIGHLY- CITED RESEARCH: IMI PROJECT RESEARCH COMPARED WITH SELECTED COMPARATORS ............................................................................................ 69 7.2.7 TRENDS IN OPEN-ACCESS RESEARCH: IMI PROJECT RESEARCH COMPARED WITH SELECTED COMPARATORS ............................................................................................ 70 7.3 SUMMARY OF BIBLIOMETRIC INDICATORS: IMI PROJECT RESEARCH COMPARED WITH SELECTED COMPARATORS ................................................................................................ 71 8 COLLABORATION NETWORK ANALYSIS BY IMI PROJECT .................................................... 72 8.1 COLLABORATION PATTERNS ACROSS THE FIVE IMI PROJECTS WITH THE GREATEST PUBLICATION PRODUCTIVITY .................................................................................. 73 8.2 COLLABORATION NETWORK GRAPHS BY IMI PROJECT .............................................. 82 9 GEOGRAPHIC CLUSTERING ANALYSIS.................................................................................... 88 ANNEX 1: BIBLIOMETRICS AND CITATION ANALYSIS .................................................................... 97 ANNEX 2: MEDICALLY RELATED JOURNAL CATEGORIES .......................................................... 108 ANNEX 3: COLLABORATION INDEX FOR ALL IMI SUPPORTED RESEARCH PROJECTS ......... 109 ANNEX 4: BIBLIOGRAPHY OF HOT PAPERS AND HIGHLY-CITED PAPERS ............................... 111 Bibliom etric analysis of IMI ongoing projects 4 1 EXECUTIVE SUMMARY This report presents a bibliometric analysis of Innovative Medicine Initiative Joint Undertaking (IMI) project research published between 2009 and 2016, using citations as an index of research quality and co-authorship as an index of collaboration. This is the eighth report commissioned by IMI. The data show that IMI continues to perform well and to rapidly expand its research effort. The overall volume of IMI project research has increased rapidly since 2009, and the initiative continues to show an exceptionally high growth in publication output. This increase is expected as the number of funded projects has increased over time rises and as the projects funded early in the history of the program begin to publish. To date, IMI projects have produced 2,686 publications which have been matched to the Clarivate Web of Science™. This represents a 60% increase from the 1,678 publications matched to the Web of Science in Report 7, which included IMI project research published between 2009 and 2015. Around three quarters of IMI project research (69.7%) has been published in high impact journals, i.e. those journals in the highest quartile ranked by Journal Impact Factor. The average Journal Impact Factor of all IMI project publications was 6.16. IMI project research was wide-ranging – the research portfolio from IMI projects covers diverse research fields from basic biological research to clinical practice. IMI project research has been published most frequently in Neurosciences, Pharmacology & Pharmacy and Rheumatology journals. The quality of IMI project research (as indexed by citation impact) has been maintained while output has grown. The citation impact of IMI project research (2.03) was twice the world average (1.00), which indicates the research was internationally influential. Between 2009 and 2016, the citation impact for