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NAT2 Involed in the Susceptibility to Antituberculosis Drug-Induced Liver Injury

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NAT2 Involed in the Susceptibility to Antituberculosis Drug-Induced Liver Injury Journal of Advances in Medicine Science Aim and Scope Journal of Advances in Medicine Science is an international, fully peer-reviewed journal covering all aspects of medical science, papers include fields of the basic and clinical medicine science research. The mission of the Journal is to foster and promote multidisciplinary studies, especially the practice, policy and theory of medicine. Its purpose is to take the lead in timely publication in the areas of medicine. Making such information available will ultimately promote the publish and exchange views of new achievements in medicine. The journal publishes regular papers, short communications, and review articles with a view of providing a focus for new information in all respects of medical science. The scope of the papers in this journal includes, but is not limited to: 1. Medical theory research 2. Clinical medicine research 3. Medical practice 4. Health care medicine 5. Preventive medicine 6. Nursing medicine 7. Medicine and medicinal chemistry 8. Hospital management 9. Integrated traditional Chinese and Western medicine treatment 10. Health policy 11. Continuing medical education 12. Health management Bilingual Publishing Co. E-Mail: [email protected] Address: 12 Eu Tong Sen Street #08-169 Singapore(059819) Journal of Advances in Medicine Science Volume 2 Issue 3 • July 2019 International Standard Serial Number: ISSN 2591-7609 (Print) ISSN 2591-7617 (Online) Editor-in-Chief: Nandagopal Sahoo, Kumaun University, India Associate Editor: Deqin Geng, XuZhou Medical University, China Jun Dou, Dongnan University, China Editorial Board Members: La Carpia, Francesca, U.S.A Passali Giulio Cesare, Italy Guanshui Bao, China Jun Wang, China Yi Yang, China Aijiao Xiao, China Qingbo Li, China Xinglun Liang, China Xianbing Hou, China Sumit Gupta, India Simran Kaur, India Qiushui He, Finland Harmandeep Singh Chahal, India Glauber SaBrando, Brazil Unai Azcarate, Spain Lu Yang, China Yos Adi Prakoso, Indonesia Ling Wang, China Sabri Uzuner, Turkey Copyright Journal of Advances in Medicine Science is licensed under a Creative Commons-Non-Commercial 4.0 International Copyright (CC BY-NC4.0). Readers shall have the right to copy and distribute articles in this journal in any form inany medium, and may also modify, convert or create on the basis of articles. In sharing and using articles in this journal, the user must indicate the author and source, and mark the changes made inarticles. Copyright © BILINGUAL PUBLISHING CO. All Rights Reserved. Contents Article 1 Research on the Interventional Effects of Stress Psychological Nursing Method on Patients with Acute Coronary Syndrome Li Zhu Guiying Yang Jing Qian Yongjing Xiang Weishu Hu 6 NAT2 Involed in the Susceptibility to Antituberculosis Drug-Induced Liver Injury Donglin Zhu Changzhi Xu Zhizhi Xie Gang Xiao Yun Xi 12 The Application of Realtime Fluorescence Quantitative PCR for Prenatal Screening of Group B Strepto- coccal Infections Changzhi Xu Donglin Zhu Zhizhi Xie Yun Xi Review 16 Comparison and Correlation Study of Polar Biomarkers of CKD Patients in Saliva and Serum by UPLC-ESI-MS Jielian Yan Baihai Su Qiang Liu Li Zhou Xiaohong Tang Yong Liu Yixiang Duan Journal of Advances in Medicine Science | Volume 02 | Issue 03 | July 2019 Journal of Advances in Medicine Science https://ojs.bilpublishing.com/index.php/jams ARTICLE Research on the Interventional Effects of Stress Psychological Nursing Method on Patients with Acute Coronary Syndrome Li Zhu1 Guiying Yang1 Jing Qian1 Yongjing Xiang1 Weishu Hu2* 1. Department of Cardiology, Jiangbei District, Chongqing General Hospital, UCAS, Chongqing, 400013, China 2. Department of Joint Surgery, Zhongshan District, Chongqing General Hospital, UCAS, Chongqing, 400014, China ARTICLE INFO ABSTRACT Article history Objective: To investigate the interventional effects of stress psycholog- Received: 16 April 2019 ical nursing method on patients with acute coronary syndrome (ACS). Methods: 100 patients with ACS who were rescued in the emergency Revised: 3 June 2019 department and department of cardiology of our hospital between January Accepted: 24 June 2019 2017 and December 2017 were enrolled. According to the random num- Published Online: 1 July 2019 ber method, the patients were divided into control group and observation group. There were 50 patients in each group. The interventions were giv- Keywords: en as routine nursing and stress psychological nursing, and the results of the two interventions were compared. Results: Before the intervention, Stress psychological nursing there was no difference in the general clinical data between the control Acute coronary syndrome (ACS) group and the observation group, which was not statistically significant; after the intervention for anxiety and depression, average hospitalization time, and off-bed time, the difference in data between the control group and the observation group on anxiety and depression was statistically significant. Moreover, the values of all the observation groups were lower than those of the control group. Conclusion: Applying stress psycholog- ical nursing method to the nursing of the patients with ACS can signifi- cantly improve their anxiety and depression, which significantly improves their quality of life, and enables the patients to better grasp the relevant health knowledge, at the same time, it obtains good intervention effects, which is worth promoting in a wider clinical scope. 1. Introduction sudden death. If the patient’s coronary arteries have devel- oped atherosclerosis and merged with the luminal stenosis cute coronary syndrome (ACS) is a group of with multiple vessels, then the blood supply from vessels clinical syndromes of coronary atherosclerotic to the corresponding blood supply parts will be reduced or Aplaque rupture or erosion, secondary to complete even interrupted, which can cause large-scale death of car- or incomplete occlusive thrombosis, including unstable diomyocytes, namely acute myocardial infarction (AMI). angina (UA), acute myocardial infarction (AMI), and [1] It is found through the survey that,[2] there are many *Corresponding Author: Weishu Hu, Department of Joint Surgery, Zhongshan District, Chongqing General Hospital, UCAS, No. 312 Zhongshan Road, Yuzhong District, Chongqing, 400014, China; E-mail: [email protected]. About the Author: First Author: Li Zhu, born in 1980, a native of Chongqing Bishan, bachelor’s degree, nurse-in-charge; Research direction: nursing. Distributed under creative commons license 4.0 DOI: https://doi.org/10.30564/jams.v2i3.975 1 Journal of Advances in Medicine Science | Volume 02 | Issue 03 | July 2019 factors that can affect the prognosis of AMI, including the the observation group patients added the stress psycholog- patients’ own factors, external environmental factors, etc., ical nursing intervention method. The main method is as but one factor should not be ignored, that is, the patients’ follows: psychology. According to the survey,[3] patients with ACS (1) The primary emphasis of this method is the nursing often experience discomfort due to severe precordial pain and intervention of the patient’s psychology, which re- and wheezing when clinical symptoms occur, after enter- quires the nursing staff to concern and care for the patients ing the hospital, there are complex psychological changes, not only from the condition of the patients, but also from the main of which are anxiety and depression. The kind their psychology. The nursing staff is aimed at the “person” of this negative emotion can have a direct impact on the who is sick, not a “sickness”. It is necessary to commu- patient’s treatment and prognosis. 100 patients with ACS nicate with the family members of the patient to maintain who were rescued in our hospital between January 2017 the observation of the patient’s emotional changes and the and December 2017 were enrolled in this research. The mutual understanding of each other. At the same time, the research on the intervention effects of stress psychological patient’s questions about the disease should be answered nursing method in the treatment of patients with ACS was with patience and meticulousness. Due to professional conducted. The report is as follows: circumstances, patients cannot understand certain com- plex medical terms and medical knowledge. Therefore, 2. Research Objects and Methods nursing staff are required to teach and communicate with patients and their families in a language style that the pa- 2.1 Research Objects tient can understand, which not only gives patients access A Retrospective analysis of 100 patients with ACS who to knowledge, but also increases patient trust in medical were rescued in our hospital between January 2017 and staff. During the work process, the nursing staff should December 2017 was performed. The age of the patients pay attention to the guidance and appeasement of the ranged from 39 to 87 years old, with an average age of negative emotions of the patients, when encountering the 63± 24 years old. The research has been approved and depression and irritability and other negative emotions passed by the Medical Ethics Committee of our hospital, of the patients, the nursing staff should not shut down and all patients and their families have signed informed or even ignore. They must communicate patiently with consent forms. the patients, conduct joint research on the causes of such problems and help patients get out of the shadow negative 2.2 Case Inclusion Criteria of emotions, and help patients build
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