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Premenstrual Dysphoric Disorder (PMDD) Premenstrual Dysphoric Disorder (PMDD) Is Associated With Estradiol- Dependent Aberrations in Intracellular Calcium Homeostasis and the Endoplasmic Reticulum Stress Response The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters Citation Li, Howard J. 2019. Premenstrual Dysphoric Disorder (PMDD) Is Associated With Estradiol-Dependent Aberrations in Intracellular Calcium Homeostasis and the Endoplasmic Reticulum Stress Response. Doctoral dissertation, Harvard Medical School. Citable link http://nrs.harvard.edu/urn-3:HUL.InstRepos:40620139 Terms of Use This article was downloaded from Harvard University’s DASH repository, and is made available under the terms and conditions applicable to Other Posted Material, as set forth at http:// nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of- use#LAA Premenstrual dysphoric disorder (PMDD) is associated with estradiol-dependent aberrations in intracellular calcium homeostasis and the endoplasmic reticulum stress response by Howard Li Submitted in Partial Fulfillment of the Requirements for the M.D. Degree with Honors in a Special Field at Harvard Medical School February 4, 2019 Area of Concentration: Reproductive Psychiatry, Molecular Biology Project Advisor: Peter J. Schmidt, MD (primary advisor) Janet M. Mullington, PhD (local advisor) Author’s Prior Degrees: B.S. Biochemistry & Cell Biology, UC San Diego, 2013 I have reviewed this thesis. It represents work done by the author under my supervision and guidance. 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