Anti-RANGAP1 monoclonal antibody, clone 2C5 (DCABH-937) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Mouse monoclonal to RanGAP1

Antigen Description GTPase activator for the nuclear Ras-related regulatory protein , converting it to the putatively inactive GDP-bound state.

Immunogen Recombinant full length Human RanGAP1 produced in HEK293T cells (NP_002874).

Isotype IgG2a

Source/Host Mouse

Species Reactivity Rat, Dog, Human

Clone 2C5

Purity Protein A purified

Purification This antibody was purified from Mouse ascites fluid by affinity chromatography.

Conjugate Unconjugated

Applications WB, IHC-P, Flow Cyt, ICC/IF

Positive Control HEK293T cell lysate transfected with pCMV6-ENTRY RanGAP1 cDNA; HEK293T cells transfected with RanGAP1 overexpress plasmid; Human liver, prostate and Human ovary adenocarcinoma tissues; HeLa and Jurkat cells; HepG2, HeLa, Jurkat, HT29, A549, MDCK, PC12 and

Format Liquid

Size 100 μl

Buffer pH: 7.30; Preservative: 0.02% Sodium azide; Constituents: 48% PBS, 50% Glycerol, 1% BSA

Preservative 0.02% Sodium Azide

Storage store at -20°C. Avoid repeated freeze / thaw cycles.

Ship Shipped at 4°C.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved INFORMATION

Gene Name RANGAP1 Ran GTPase activating protein 1 [ Homo sapiens ]

Official Symbol RanGAP1

Synonyms RANGAP1; Ran GTPase activating protein 1; SD, segregation distorter homolog (Drosophila); ran GTPase-activating protein 1; Fug1; KIAA1835; segregation distortion; segregation distorter homolog; SD; MGC20266;

Entrez Gene ID 5905

Protein Refseq NP_002874

UniProt ID A0A024R1U0

Chromosome Location 22q13

Pathway Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; DNA Replication, organism-specific biosystem; Disease, organism-specific biosystem; HIV Infection, organism-specific biosystem; HIV Life Cycle, organism-specific biosystem; Host Interactions of HIV factors, organism-specific biosystem;

Function GTPase activator activity; Ran GTPase activator activity; protein binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved