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The Toxicologist: Late-Breaking Supplement These abstracts also are available via the SOT Event App and the Online Planner. All late-breaking abstracts are presented on Thursday, March 19, 8:30 am–11:30 am. www.toxicology.org Publication Date: March 11 , 2020 Preface This issue is devoted to the abstracts of the Late-Breaking Poster Session of the 59th Annual Meeting of the Society of Toxicology, held at the Anaheim Convention Center, Anaheim, California, March 15–19, 2020. The abstracts are reproduced as accepted by the Scientific Program Committee of the Society of Toxicology and appear in numerical sequence. If a number is missing in the numerical sequence, the abstract assigned to the missing number was withdrawn by the author(s). Author names that are underlined in the author block indicate the author is a member of the Society of Toxicology. For example, J. Smith. SOT members may sponsor abstracts that do not include an author with SOT membership. Authors who are members of designated organizations could serve as the sponsor of the abstract if an SOT member was not a co-author; these types of sponsorships are displayed as follows: Sponsor: J. Doe, Organization Name. The 2020 SOT Event App and Online Planner The Event App is available via the SOT Annual Meeting website and app marketplaces. The Event App, alongside the Online Planner available on the SOT Annual Meeting website, enables attendees to engage with the organizers, exhibitors, and each other and to manage their time and maximize their experience during the Annual Meeting. You also can access ePosters electronically via the Event App until May 15, 2020. To cite a 2020 SOT Annual Meeting Late-Breaking Abstract, please format as follows: The Toxicologist: Late-Breaking Supplement, Supplement to Toxicological Sciences, 168 (1), Abstract #__ , 2020, Title, First Author. Society of Toxicology 11190 Sunrise Valley Drive, Suite 300, Reston, VA 20191 www.toxicology.org © 2020 Society of Toxicology All text and graphics are © 2020 by the Society of Toxicology unless noted. For promotional use only. No advertising use is permitted. This abstract book has been produced electronically by the Society of Toxicology. Every effort has been made to faithfully reproduce the abstracts as submitted. The author(s) of each abstract appearing in this publication is/are solely responsible for the content thereof; the publication of an abstract shall not constitute or be deemed to constitute any representation by the Society of Toxicology or its boards that the data presented therein are correct or are sufficient to support the conclusions reached or that the experiment design or methodology is adequate. Because of the rapid advances in the medical sciences, SOT recommends that independent verification of diagnoses and drug dosage be made. The Toxicologist: Late-Breaking Supplement 2020 i THURSDAY POSTER SESSION MAP March 19, 2020—8:30 AM to 11:30 AM—Hall C Poster Setup—8:00 AM to 8:30 AM Late‐Breaking Poster #s: P101–P411 P391 P392 P393 P394 P395 P396 P397 P398 P399 P400 P401 P402 P403 P404 P405 P406 P407 P408 P409 P410 P411 P390 P389 P388 P387 P386 P385 P384 P383 P382 P381 P380 P379 P378 P377 P376 P375 P374 P373 P372 P371 P370 P349 P350 P351 P352 P353 P354 P355 P356 P357 P358 P359 P360 P361 P362 P363 P364 P365 P366 P367 P368 P369 P348 P347 P346 P345 P344 P343 P342 P341 P340 P339 P338 P337 P336 P335 P334 P333 P332 P331 P330 P329 P328 P307 P308 P309 P310 P311 P312 P313 P314 P315 P316 P317 P318 P319 P320 P321 P322 P323 P324 P325 P326 P327 P306 P305 P304 P303 P302 P301 P300 P299 P298 P297 P296 P295 P294 P293 P292 P291 P290 P289 P288 P287 P286 P265 P266 P267 P268 P269 P270 P271 P272 P273 P274 P275 P276 P277 P278 P279 P280 P281 P282 P283 P284 P285 P264 P263 P262 P261 P260 P259 P258 P257 P256 P255 P254 P253 P252 P251 P250 P249 P248 P247 P246 P227 P228 P229 P230 P231 P232 P233 P234 P235 P236 P237 P238 P239 P240 P241 P242 P243 P244 P245 P226 P225 P224 P223 P222 P221 P220 P219 P218 P217 P216 P215 P214 P213 P212 P211 P210 P209 P208 P207 P206 P185 P186 P187 P188 P189 P190 P191 P192 P193 P194 P195 P196 P197 P198 P199 P200 P201 P202 P203 P204 P205 P184 P183 P182 P181 P180 P179 P178 P177 P176 P175 P174 P173 P172 P171 P170 P169 P168 P167 P166 P165 P164 P143 P144 P145 P146 P147 P148 P149 P150 P151 P152 P153 P154 P155 P156 P157 P158 P159 P160 P161 P162 P163 P142 P141 P140 P139 P138 P137 P136 P135 P134 P133 P132 P131 P130 P129 P128 P127 P126 P125 P124 P123 P122 P101 P102 P103 P104 P105 P106 P107 P108 P109 P110 P111 P112 P113 P114 P115 P116 P117 P118 P119 P120 P121 Entrance Entrance Photography or electronic capture of posters is prohibited without the consent of the poster presenter(s)/author(s). Please respect your colleagues’ right to privacy. nd UND a E 5 R 1 All text and graphics are © 2020 by the Society of Toxicology. All rights reserved. No text or graphics may be copied or used without written permission from the Society of Toxicology. For further information, please contact SOT Headquarters. For promotional use only. No advertising use is permitted. The Toxicologist: Late-Breaking Supplement 2020 ii Thursday, March 19, Poster Session by Location SESSION TITLE ABSTRACT #s POSTER BOARD #s Late-Breaking 1: Nanotoxicology; Computational; Modeling; 3288–3336 P101–P149 Systems Biology; Emerging Technologies Late-Breaking 2: Animal Models; Alternatives to Mammalian Models; 3337–3364 P150–P177 Immunotoxicity; Inflammation Late-Breaking 3: Exposure; Risk, Safety Asssessment 3365–3415 P178–P228 Late-Breaking 4: Mixtures; Metals; Pesticides; Neurotoxicity 3416–3463 P230–P277 Late-Breaking 5: Food Safety; Natural Products; Ecotoxicology; Skin; 3464–3487 P279–P302 Public Health Late-Breaking 6: Biomarkers; Genotoxicity; Endocrine; Clinical and 3488–3519 P303–P334 Translational Toxicology Late-Breaking 7: Carcinogenesis; Cardiovascular; Kidney; Liver 3520–3546 P335–P361 Late-Breaking 8: Reproductive and Developmental Toxicology; 3547–3562 P363–P378 Epigenetics Late-Breaking 9: Air Pollution; PFAS; Respiratory 3563–3594 P379–P410 Late-Breaking 10: Emerging Technologies II 3595 P411 The Toxicologist: Late-Breaking Supplement 2020 iii Thursday, March 19, Poster Session by Topic TOPIC ABSTRACT #s BOARD #s SESSION TITLE Air Pollution Toxicology 3563–3578 P379–P394 Late-Breaking 9 Alternatives to Mammalian Models 3342–3352 P155–P165 Late-Breaking 2 Animal Models 3337–3341 P150–P154 Late-Breaking 2 Autoimmunity/Hypersensitivity 3353 P166 Late-Breaking 2 Bioinformatics 3318–3321 P131–P134 Late-Breaking 1 Biological Modeling 3314–3317 P127–P130 Late-Breaking 1 Biomarkers 3488–3492 P303–P307 Late-Breaking 6 Biotransformation/Cytochrome P450 3493–3494 P308–P309 Late-Breaking 6 Carcinogenesis 3520–3532 P335–P347 Late-Breaking 7 Cardiovascular Toxicology/Hemodynamics 3533–3536 P348–P351 Late-Breaking 7 Chemical Threats and Bioterrorism 3476 P291 Late-Breaking 5 Clinical and Translational Toxicology 3514–3517 P329–P332 Late-Breaking 6 Computational Toxicology and Data Integration 3301–3313 P114–P126 Late-Breaking 1 Developmental and Juvenile Toxicology 3554–3556 P370–P372 Late-Breaking 8 Disposition/Pharmacokinetics 3495–3500 P310–P315 Late-Breaking 6 Ecotoxicology 3477–3479 P292–P294 Late-Breaking 5 Emerging Technologies 3323–3324; P135–P136; Late-Breaking 1 3595 P411 Late-Breaking 10 Endocrine Toxicology 3501–3505 P316–P320 Late-Breaking 6 Epidemiology and Public Health 3482–3487 P297–P302 Late-Breaking 5 Epigenetics 3557–3562 P373–P378 Late-Breaking 8 Exposure Assessment/Biomonitoring 3365–3372 P178–P185 Late-Breaking 3 Food Safety/Nutrition 3464–3471 P279–P286 Late-Breaking 5 Gene Regulation/Signal Transduction 3506 P321 Late-Breaking 6 Genotoxicity/DNA Repair 3507–3513 P322–P328 Late-Breaking 6 Immunotoxicity 3354–3360 P167–P173 Late-Breaking 2 Inflammation 3361–3364 P174–P177 Late-Breaking 2 Liver 3539–3546 P354–P361 Late-Breaking 7 The Toxicologist: Late-Breaking Supplement 2020 iv Thursday, March 19, Poster Session by Topic (Continued) TOPIC ABSTRACT #s BOARD #s SESSION TITLE Medical Devices 3324 P137 Late-Breaking 1 Metals 3421–3433 P235–P247 Late-Breaking 4 Mixtures 3416–3420 P230–P234 Late-Breaking 4 Nanotoxicology 3288–3300 P101–P113 Late-Breaking 1 Natural Products 3473–3475 P288–P290 Late-Breaking 5 Neurotoxicity and Neurodegenerative Disease 3440–3462 P254–P276 Late-Breaking 4 Nonchemical Stressors and Cumulative Risk 3373 P186 Late-Breaking 3 Assessment Ocular Toxicology 3518–3519 P333–P334 Late-Breaking 6 Oxidative Injury and Redox Biology 3538 P353 Late-Breaking 7 Perfluorinated Alkyl Substances (PFAS) 3579–3584 P395–P400 Late-Breaking 9 Persistent Organic Pollutants (POPs) 3463 P277 Late-Breaking 4 Pesticides 3434–3439 P248–P253 Late-Breaking 4 Regulation/Policy 3481 P296 Late-Breaking 5 Reproductive Toxicology 3547–3553 P363–P369 Late-Breaking 8 Respiratory Toxicology 3585–3594 P401–P410 Late-Breaking 9 Risk Assessment 3374–3391 P187–P204 Late-Breaking 3 Safety Assessment: Nonpharmaceutical 3392–3394 P205–P207 Late-Breaking 3 Safety Assessment: Pharmaceutical 3395–3415 P208–P228 Late-Breaking 3 Skin 3480 P295 Late-Breaking 5 Stem Cell Biology and Toxicology 3325–3332 P138–P145 Late-Breaking 1 Systems Biology and Toxicology 3333–3336 P146–P149 Late-Breaking 1 The Toxicologist: Late-Breaking Supplement 2020 v Society of Toxicology 59th Annual Meeting Late‐Breaking Abstracts ABSTRACT NUMBER: 3288 Poster Board Number: P101 TITLE: Sonication Effect on Graphene Oxide Dispersion Dictates Toxicity Response in RAW264.7 Macrophages AUTHORS (FIRST INITIAL, LAST NAME) AND INSTITUTIONS: D. Diaz‐Diestra1, B. Thapa2, F. Fisol3, N. Konduru4, J. Beltran‐Huarac5, G. Morell1, and B. Weiner1. 1University of Puerto Rico, San Juan, PR; 2University of Texas Southwestern Medical Center, Dallas, TX; 3Harvard University, Boston, MA; 4University of Texas Health Science Center, Tyler, TX; and 5East Carolina University, Greenville, NC.
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