US HUPO 2019 Galisteo Street, Bldg I-1 Santa Fe, NM 87505 505-989-4876 • [email protected] • 2019 CONFERENCE ORGANIZERS
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US HUPO FIFTEENTH ANNUAL CONFERENCE US HUPO MAJOR SPONSORS Platinum Sponsors Pressure Biosciences, Inc. Shimadzu Thermo Fisher Scientific TABLE OF CONTENTS Conference Organizers and Board of Directors ...................................... 2 Overview of Program + Activities ............................................................ 3 General Information + Hotel Map ............................................................ 4 Exhibitors ................................................................................................5 Awards ....................................................................................................7 Sunday Opening Session + Plenary Lecture .......................................... 9 Monday Lunch ......................................................................................12 Tuesday ................................................................................................14 Tuesday Lunches .................................................................................. 17 Wednesday ...........................................................................................20 Oral Abstracts .......................................................................................22 Poster List .............................................................................................35 Poster Abstracts .................................................................................... 46 Author Index .......................................................................................... 90 US HUPO 2019 Galisteo Street, Bldg I-1 Santa Fe, NM 87505 505-989-4876 • [email protected] • www.USHUPO.org 2019 CONFERENCE ORGANIZERS Steven A. Carr, Broad Institute Ileana Cristea, Princeton University David Fenyo, New York University School of Medicine Aleksandra Nita-Lazar, NIAID, NIH US HUPO 2018 – 2019 BOARD OF DIRECTORS President, Ileana Cristea, Princeton University Treasurer, David Fenyo, New York University School of Medicine Secretary, Olga Vitek, Northeastern University Past-President, David Muddiman, North Carolina State University David Arnott (Genentech) Alexey Nesvizhskii (University of Michigan) Nuno Bandeira (UCSD) Gil Omenn (University of Michigan) Ralph Bradshaw (University of California, San Francisco) Laurie Parker (University of Minnesota) Josh Coon (University of Wisconsin, Madison) Peipei Ping (UCLA) Catherine Costello (Boston University) Fred Regnier (Purdue University) Benjamin Garcia (University of Pennsylvania) Karin Rodland (Pacific Northwest National Laboratory) David Goodlett (University of Maryland, Baltimore County) Henry Rodriguez (NIH, NCI) Timothy Griffin (University of Minnesota) Birgit Schilling (Buck Institute on Aging) Lan Huang (University of California, Irvine) Michael Snyder (Stanford University) Lingjun Li (University of Wisconsin - Madison) David Speicher (Wistar Institute, Univ of Pennsylvania) Daniel Liebler (Vanderbilt University) Hanno Steen (Harvard University) Joseph Loo (University of California, Los Angeles) W. Andy Tao (Purdue University) Michael MacCoss (University of Washington) Jennifer Van Eyk (Cedars-Sinai Medical Center) Robert Moritz (Institute for Systems Biology) Cathy Wu (University of Delaware) Arthur Moseley (Duke University) John Yates (The Scripps Research Institute) 2 PROGRAM OVERVIEW SAT, MARCH 2 - MON, MARCH 4 TUES, MARCH 5 WED, MARCH 6 SUN, MARCH 3 8:00 – 8:30 am 8:00 – 8:30 am 8:00 – 8:30 am Early Morning Coffee Early Morning Coffee Early Morning Coffee Exhibits & Posters Exhibits & Posters Exhibits & Posters 8:30 – 9:20 am 8:30 – 9:20 am 8:30 – 9:20 am SATURDAY Plenary Session Plenary Session Plenary Session Donald F. Hunt Distinguished New Investigator Award Lightning Talks: Tips & Tricks 9:00 am - 4:00 pm Achievement in Proteomics Wilhelm Haas Full-Day Course, Day 1 Award Lecture Computational Proteomics: Design and Analysis of Jennifer Van Eyk Juergen Cox Quantitative Proteomics Experiments 9:20 – 9:50 am 9:20 – 9:50 am 9:20 – 9:50 am SUNDAY Coffee Break with Exhibits & Posters Coffee Break with Exhibits & Posters Coffee Break 9:00 am - 4:00 pm 9:50 – 11:10 am 9:50 – 11:10 am 9:50 – 11:10 am Full-Day Course, Day 2 Parallel Sessions Parallel Sessions Parallel Sessions Design and Analysis of Proteome Organization in Protein Interactions and Posttranslational Regulation, Quantitative Proteomics Space and Time, Plaza Ballroom Signaling, Plaza Ballroom Plaza Ballroom Experiments Immunity and the Microbiome Glycoproteomics in Biology 9:00 am - 12:00 pm Roosevelt-Madison Room Infectious Disease and Medicine, Roosevelt- Morning Courses Roosevelt-Madison Room Madison Room Cross-Linking Mass Spectrometry 11:10 am – 12:00 pm 11:10 am – 12:00 pm 11:10 am – 12:00 pm Plenary Session Plenary Session Lifetime Achievement in Glycomics and Lightning Talks – Round I Lightning Talks – Round II Proteomics Glycoproteomics: Plaza Ballroom Plaza Ballroom Catherine E. Costello Basics Plaza Ballroom 1:00 – 4:00 pm 12:15 – 1:30 pm 12:15 – 1:30 pm Afternoon Courses Bruker Lunch Seminar, SCIEX Lunch Seminar, Glycomics and Regency Room Potomac Room Glycoproteomics: Advanced Thermo Lunch Seminar, Regency Room Stable and Transient 1:30 - 3:00 pm 1:30 - 3:00 pm Protein-Protein Poster Session Poster Sessions Interactions Exhibits & Posters, Atrium Exhibits & Posters, Atrium 3:00 – 4:20 pm 3:00 – 4:20 pm 4:30 – 5:30 pm Parallel Sessions Parallel Sessions Parallel Workshops Multi-omics, Plaza Ballroom Cancer Early Detection and Interactive Career Prevention, Plaza Ballroom Planning Workshop for Metabolism and Disease graduate students and , Roosevelt-Madison Room Informatics: Emerging postdocs and New Approaches Roosevelt-Madison Room 4:30 – 5:50 pm 4:30 – 5:50 pm Parallel Sessions Parallel Sessions 6:00 – 7:00 pm Advances in Technology Protein Proteoforms in Opening Plaza Ballroom Health and Disease Plenary Lecture Plaza Ballroom Steven Gygi Structural and Chemical Plaza Ballroom Proteomics Aging and Neurological Diseases Roosevelt-Madison Room Roosevelt-Madison Room 5:50 – 6:30 pm 6:00 – 7:30 pm 7:00 – 8:30 pm Mixer with Exhibitors Workshops Opening Reception Poster-Exhibits, Atrium Biomarkers for early detection: Mixer featuring exhibits What should we measure? Atrium Roosevelt-Madison Room Grantwriting, Regency Room 6:30 – 8:00 pm Workshop 7:30 – 9:00 pm NIH Roundtable Social Event, Light Supper Roosevelt-Madison Room Atrium 3 GENERAL INFORMATION VENUE. All meetings, sessions, and exhibits are at the INTERNET ACCESS. WiFi Is available for conference Hilton Rockville. attendees in the meeting areas. Look for walk-in slides and signage for details on network ID and password. PROGRAM. The abstracts for the talks and posters appear in this book and are arranged in the order of LUNCH SEMINARS. Free lunch seminars are hosted on presentation. The author index references the day and Monday and Tuesday in meeting rooms (Regency and type of presentation. Potomac Rooms). All attendees are invited to attend, but are encouraged to RSVP at host company exhibit booths. POSTERS AND EXHIBITORS. Posters are located in the See program schedule for details. hotel’s Atrium. All posters should be mounted by Monday morning 9:30 am. Exhibit booths will be in place from JOB BOARD. Located in Plaza foyer near Registration. Sunday evening welcome reception through Tuesday at 3:00 pm (conclusion of Poster Session on Tuesday.) PHONES AND OTHER DEVICES. Please TURN OFF all devices (phones, tablets, etc) when in lecture rooms. This Posters are presented/attended on both Monday and courtesy is requested on behalf of presenters as well as Tuesday as follows: fellow audience members. Odd-numbered posters 1:30-2:15 pm Even-numbered posters 2:15-3:00 pm NO PHOTOGRAPHY or RECORDING of posters or talks is permitted. TALKS. There are two session rooms located in the hotel’s meeting space area, Plaza Ballroom and the Roosevelt- YOGA – NAMASTE, Tuesday, 7:00 am, Potomac Room. Madison Room. Join us for an all-levels early morning yoga class. No yoga outfits required, just loose-fitting clothing. We will have All speakers must appear at least 20 minutes prior to the towels for you to use as ‘yoga mats’. start of their sessions. Speakers using their own laptops will use this time to connect laptops and assure SOCIAL EVENT ON TUESDAY. Supper-style event in the compatibility with the projector. Speakers using the Atrium featuring live jazz. conference PC computer will use this time to load their files. US HUPO 2020 March 8 - 11, 2020 Westin Seattle Short Courses March 7 - 8 Organizers Lan Huang | Karin Rodland Birgit Schilling | Judit Villen 4 EXHIBITORS US HUPO is pleased to acknowledge the support of conference exhibitors. Exhibit booths are located immediately outside the session rooms along with the technical posters. Sunday welcome reception, Monday-Tuesday coffee breaks, and Monday mixer will be located here with the exhibitors. VENDOR LUNCH SEMINARS The following companies offer lunch seminars to conference participants on Monday and Tuesday. Seating is limited. Please reserve a seat at company exhibit booths. Monday, 12:15 – 1:30 pm Tuesday, 12:15 – 1:30 pm See program schedule for descriptions. See program schedule for descriptions. Bruker, Regency Room Thermo Scientific, Regency Room SCIEX, Potomac 5 6 AWARDS DONALD F. HUNT DISTINGUISHED CONTRIBUTION TO PROTEOMICS AWARD Award presentation and talk, Monday 8:30 am, Plaza Ballroom The Donald F. Hunt Distinguished Achievement in Proteomics award recognizes a focused or singular achievement in the field of proteomics.