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Roberto Kolter Knowing I’M One of the Points,” He Says

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Roberto Kolter Knowing I’M One of the Points,” He Says CAREERS Dodd chose to shift his research focus elsewhere. “I sometimes found it weird to be in the lab,” he says. He was one of TURNING POINT several patients who had the mutation, yet no symptoms, and so had MRI scans in their lab. “It was weird to see a bar graph, Roberto Kolter knowing I’m one of the points,” he says. The research could be emotionally taxing. “It would feel odd to work on, for example, Roberto Kolter set up his microbiology a mouse with the same genetic mutation laboratory at Harvard Medical School in as me, and wonder if I would respond Boston, Massachusetts, in 1983. Postdocs EINAT SEGEV EINAT similarly,” he says. But he did want to keep worldwide hope to join his lab because of his working on the heart, so he is now a postdoc career-targeted training philosophy, but with studying the cardiac effects of diabetes, a rare exceptions, he brings in only those who disease that his grandfather had. already have a fellowship. SPOTLIGHT SCARS Why do you accept postdocs only if they have The emotional toll can be especially intense their own funding? when media attention forces the scientist I focus on those whom I believe have a fan- into the public eye. Wartman felt the land- tastic chance of getting their own funding as a scape shift after a high-profile piece about principal investigator. I think it’s unfair for me him appeared in the New York Times in 2012. to interview those who have very little chance He is happy that patients find his personal of getting their own funding, considering how perspective helpful, but regrets that the deci- competitive the academic job market is and sion to share his story no longer rests with how important it is to show independence. project with them once they leave, to help him. “It’s still not the easiest topic for me to them to set up their own lab. That gives the talk about,” he says. “The last time I relapsed, What does your laboratory focus on? postdocs who are leaving a good opportunity I came close to dying. To rehash that on a I let the postdocs explore what they want to to establish themselves without having to com- regular basis is emotionally draining.” explore, as long as it is within the sphere of my pete with me and the people in my lab. Media attention can change one’s entire interest. I’ve worked on starvation physiology, research career. Kay Redfield Jamison, a biofilms, signalling, experimental evolution, What careers do your postdocs pursue? clinical psychiatrist and founder of a clinic antibiotics and many other subjects. About half the 100 or more postdocs that have for mood disorders at the University of gone through my lab hold full-time academic California, Los Angeles, channelled Describe your training philosophy. jobs, of which running a research lab is a big her struggles with bipolar disorder into I train people to go on into academia, industry component. Many people whom I take on research on the illness’s wide range of effects the corporate world or whatever they want to as postdocs want a job in the biotechnology — from enhanced creativity to a high risk go into. We need to give them the experience arena. The other 50% are dominated by those of suicide. But when she wrote her autobi- that they require, including learning how to who choose to join a company. Those can ography in 1995, entitled An Unquiet Mind: teach and learning how to manage. Postdocs range from start-up biotech companies to very A Memoir of Moods and Madness, she knew are not just there to come to the lab so that well-established pharmaceutical or chemical that her professional life would never be the principal investigators can get their next grant. companies. Others lead research groups at same. She gave up her clinical practice. “You institutes or government labs, work as research can’t say that you’ve been psychotic and What stands out when you look at applications? associates, teach science or do other science- nearly died by suicide and expect people to I have learned that networking works very, related work. Only two have left science. look at you the same way,” she says. very well. If I know who trained that indi- Now at Johns Hopkins University in vidual, and I know and respect them, then I’ll Do they get permanent positions right away? Baltimore, Maryland, Jamison focuses on know a lot about how this postdoc will work No one who has come through my lab has had writing and public speaking. She credits a in the lab. But that does not mean that if I don’t to leave science because they could not get a network of supportive friends and colleagues know the mentor I will close the door to the job. Personally, I believe that I have failed a for helping her to navigate her career ups postdoc. They need to have also done their postdoc if I take them into my lab and they and downs. “Becoming a poster child for an homework — they need to know how I train cannot get a job that they love when they leave. illness is draining,” she says. “It becomes a people and how they think they would fit in. That usually means that they have to go on to disturbing part of your identity.” Still, it was do a second postdoc. There have been very worth it to reach others who were suffering. When have you made exceptions? few such individuals — fewer than five, in the “That’s what good comes out of it.” There are one or two cases where I was com- 32 years I have had my own lab. So overall I At the end of the day, that desire to aid pletely sure that they would get a fellowship, and rate my success rate in helping postdocs get others motivates many researchers to they didn’t. But by then I had gotten so excited their first job at about 90%. continue their work even though their own about the project we had co-developed that I health is poor. “Leukaemia disrupted my chose to support them from my own funds. What do you see as the role of a postdoc? career and goals and was a huge setback in The meaning of postdoctoral training has been my life,” Wartman says. “At the same time, if How does your lab develop a research project? lost in today’s scientific community. As men- I can turn my own struggle into a story that The ideas often emerge from conversations tors, we need to really reconsider what we are helps other people, that has value.” ■ that start about 18 months before the postdoc training postdocs for. And that’s just it: it’s a comes to work with me. It has almost always training period, not a job. ■ Virginia Gewin is a freelance writer in been my policy that incoming postdocs build Portland, Oregon. their research projects and are free to take the INTERVIEW BY JULIE GOULD 28 MAY 2015 | VOL 521 | NATURE | 553 © 2015 Macmillan Publishers Limited. All rights reserved.
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