DIABETES YOUR TAKE CONTROL GUIDE Medications

The first way to treat type 2 COMMON BLOOD PRESSURE MEDICATIONS diabetes is often meal planning, DRUG CLASS GENERIC NAME BRAND NAME weight loss, and exercise. Often ACE Inhibitors Benazepril Lotensin these steps are not enough to Lower blood pressure by Captoril Capoten bring your ABCs to a healthy keeping your blood vessels Enalapril/Enalaprilat Vasotec relaxed. ACE inhibitors Fosinopril Monopril range. The next step is taking prevent a hormone from Lisinopril Prinivil, Zestril medication. forming in your body and narrowing your blood Moexipril Univasc Your doctor will decide which vessels. They also help Perindopril Aceon medication is right for you. protect your kidneys and Quinapril Accupril reduce your risk of heart Ramipril Altace This depends on: attack and stroke. Trandolapril Mavik Candesartan Atacand • Your lifestyle ARBs Keep the blood vessels Eprosartan Teveten • Physical condition open and relaxed Irbesartan Avapro • How you respond to the to help lower blood Losartan Cozaar medicine pressure. Like ACE Olmesartan Benicar inhibitors, ARBs also Valsartan Diovan protect your kidneys. • Insurance coverage Telmisartan Micardis Acebutolol Sectral Aspirin Atenolol Tenormin Beta Blockers Betaxolol If you are at high risk for or if Help lower blood Bisoprolol Zebeta you have heart disease, taking pressure and a low dose aspirin every day relax your heart Carvedilol Coreg Labetalol Trandate may help. Aspirin can also help by allowing it to beat slower and Metoprolol Lopressor/Toprol XL people who have had a heart with less force. Nadolol Corgard attack or stroke. Ask Beta blockers Nebivolol Bystolic help prevent heart your doctor whether you Penbutolol Levatol attack and stroke. should take aspirin. Pindolol ...... Propranolol Inderal/Inderal LA Timolol Blood pressure Amlodipine Norvasc Clevidipine Cleviprex medications Calcium Diltiazem Cardizem/Dilacor XR/Tiazac Not everyone takes the same Channel Blockers Felodipine Plendil Help the blood blood pressure medicine. Isradipine DynaCirc CR vessels relax by Nicardipine Cardene Many people take two or more keeping calcium medications. The ones you out of your blood Nifedipine Adalat CC/Procardia take will depend on your blood vessels and heart. Nimodipine pressure numbers and other Nisoldipine Sular factors. Verapamil Calan/Covera HS/Isoptin/Verelan Chlorothiazide Diuril Chlorthalidone Thalitone Some medications include Diuretics Furosemide Lasix more than one drug and Help rid your body Hydrochlorothiazide Microzide/Oretic of extra water and Hydroflumethiazide Saluron might have a different name. sodium through Indapamide Talk to your doctor about urine. Sometimes what medication or called “water pills.” Methyclothiazide Enduron Metolazone Zaroxolyn medications would Spironolactone Aldactazide/Aldactone work for you. Torsemide Demadex DIABETESFORECAST.ORG

Medications (continued)

Cholesterol CHOLESTEROL MEDICATIONS medications DRUG CLASS GENERIC NAME BRAND NAME Most adults with diabetes who Atorvastatin Lipitor are 40 years or older should Fluvastatin Lescol be taking a statin. Lovastatin Mevacor Statins Lovastatin extended-release Altoprev Help lower Pitavastatin Livalo LDL levels There are other medicines and reduce Pravastatin Pravachol your risk for that improve cholesterol. Ask Rosuvastatin Crestor heart attack your doctor about whether or stroke. Simvastatin Zocor you should take a statin or Lovastatin/niacin extended-release Advicor other drug to lower your Simvastatin/niacin extended-release Simcor risk for heart attack or Simvastatin/ezetimibe Vytorin stroke......

Diabetes oral DIABETES ORAL MEDICATIONS DRUG CLASS GENERIC NAME BRAND NAME COST* medications Biguanides There are different Decrease amount of glucose Metformin Glucophage Low types, or classes, produced by the liver. of drugs that work Chlorpropamide Diabinese in different ways to Sulfonylureas Glimepiride Amaryl lower blood glucose. Help beta cells in pancreas Low release more insulin. Glipizide Glucotrol/Glucotrol XL Glyburide/Glibenclamide Micronase/Glynase/Diabeta Oral Combination Meglitinides Nateglinide Starlix Therapy Help beta cells in pancreas Moderate Because the drugs release more insulin. Repaglinide Prandin listed on the right act TZDs Pioglitazone Actos in different ways to Help insulin work better Low lower blood glucose in muscle and fat. Lower Rosiglitazone Avandia levels, they may glucose production in liver. be used together. Alpha-Glucosidase Inhibitors Acarbose Precose Block the breakdown of For example, a Moderate biguanide and a starches, such as potatoes and pasta in intestine. Meglitol Glyset sulfonylurea may be used together. Many DPP-4 Inhibitors Alogliptin Nesina combinations are Prevent breakdown of Linagliptin Tradjenta GLP-1, a compound in the High prescribed together body that lowers blood Saxagliptin Onglyza as a single pill for glucose levels. Sitagliptin Januvia convenience. Bile Acid Sequestrants Lower cholesterol and blood Colesevelam Welchol High glucose levels. Dopamine-2 Agonists *Cost is based on Bromocriptine Help lower blood glucose Cycloset, Parlodel High (quick release) the lowest-price levels after a meal. drug in its class. SGLT2 Inhibitors Canagliflozin Invokana Blocks glucose from being Dapagliflozin Farxiga High reabsorbed in the kidney. Empagliflozin Jardiance DIABETES YOUR TAKE CONTROL GUIDE

Medications (continued) INSULIN INSULIN TYPE* GENERIC NAME BRAND NAME Insulin Rapid-Acting Aspart NovoLog Onset: about 15 minutes Glulisine Apidra There are different types of Peak: about 1 or 2 hours after injection insulin that vary in how quickly Duration: last between 2-4 hours Lispro Humalog they lower blood glucose Regular- or Short-Acting levels. Some work very quickly Onset: about 30 minutes Human Regular Humulin R/Novolin R and are taken with meals. Peak: about 2 to 3 hours after injection Others are long-acting and are Duration: last between 3-6 hours used just once or twice a day. Intermediate-Acting Onset: about 2 to 4 hours after injection Peak: 4 to 12 hours later Human NPH Humulin N/Novolin N Duration: it is effective for about 12 to 18 hours

Long-Acting or Basal Insulin Analogs Degludec Tresiba Onset: between 2 and 4 hours Peak: continuous, “peakless” action that acts Detemir Levemir the way your body normally releases insulin Duration: last up to 24 hours Glargine Lantus Ultra Long-Acting Onset: 6 hours Glargine U-300 Toujeo Peak: No peak Duration: 36 hours *Costs for insulin vary due to Inhaled Insulin types and doses. Onset: Within 12 to 15 minutes Peak: 30 minutes Technosphere Duration: Out of your system in 180 minutes insulin-inhalation Afrezza Note: Must be used with injectable system long-acting insulin in patients with type 1 diabetes and in type 2 diabetes patients who use long-acting insulin...... Other injected OTHER INJECTED MEDICATIONS medications DRUG CLASS GENERIC NAME BRAND NAME COST* In addition to pills and Amylin Slows food moving Pramlintide Symlin High insulin, some medications for through the stomach. controlling your blood glucose Albiglutide Eperzan/Tanzeum are injected. GLP-1 Receptor Agonists Dulaglutide Trulicity Helps release insulin when Exenatide Byetta High blood glucose is high and Exenatide lower the amount of glucose Bydureon Extended Release produced by the liver. Liraglutide Victoza

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What if my blood Diabetes and Important note: glucose stays too high? pregnancy The generic names and brand names are shown If your blood glucose levels If you’re pregnant, to help you know what you take. The American remain too high, your talk with your health Diabetes Association does not recommend or medication may need to be care provider about endorse any specific medication. adjusted. Do not adjust your what medications You might take a medication that is not on this medication on your own. Talk are right for list. Your healthcare team is your best source of to your doctor about you. information. Talk to them about all the medications possible changes. you take. Never stop taking a medication or change your dose without talking with your doctor.