Corporate Information / Stock Information 89 investment Percentage of Percentage Annual Report 2014 Report Annual 1.5% 1.5% Other institutions 5.2% investors Foreign 0.4% 0.4% Securities firms Financial institutions Thousands of shares 14/4 14/4 0.8% 5,5163,310 6.7% 2,7942,398 4.0 3.4 1,861 2.9 1,836 2.3 2.2 1,5681,438 1.9 1.7 Number of shares held shares 92.1% 92.1% investors Individual Individual 0.0% By number of shareholders Treasury stock Treasury Santen Pharmaceutical Co., Ltd. Co., Pharmaceutical Santen 13/4 13/4 0.9% Securities firms 35.1% 9.6% Other institutions Financial Financial 0.0% 0.0% stock Treasury institutions % 8.9 8.9 45.5% Foreign Foreign investors investors Individual 12/4 12/4 By number of shares Composition of Shareholders Composition Major Shareholders Name Service Bank, Ltd. Trustee 505223 Company Bank and Trust State Street 5,463Development Bank of Japan Inc. Bank of Japan, Ltd. The Master Trust Nippon Life Insurance Company 6.6 UFJ, Ltd.The Bank of Tokyo-Mitsubishi Ono Pharmaceutical Co., Ltd. Ltd. Daiichi Sankyo Company, 2,120Gic Private, Ltd. National Mutual Insurance Federation of Agricultural Cooperatives 2.6 2014 6,150 4,065 11/4 11/4 10/4 10/4 Exchange and the Securities Exchange were Exchange were Exchange and the Osaka Securities integrated on July 16, 2013. Santen Pharmaceutical Co., Ltd. Santen Pharmaceutical A, Osaka Tower Grand Front Kita-ku, Osaka 530-8552, 4-20 Ofuka-cho, Japan URL: http://www.santen.com contact: Investor relations TEL: +81-6-6321-7000 (Main) E-MAIL: [email protected] +81-6-4802-9360 (IR) 1890 ¥7,264 million 7,780 Tokyo 4536 Osaka Corporate Agency Division, and Banking Corporation Mitsubishi UFJ Trust 6-3, Fushimi-cho 3-chome, Chuo-ku, Osaka 541-8502, Japan and Fukuoka Nagoya, Osaka Sendai, Tokyo, Noto and Shiga and Development Center Nara Research 3,072 (non-consolidated: 1,878) 82,582,903 * The cash equity markets of the Tokyo Stock The cash equity markets of the Tokyo * (Yen) 2010 2011 2012 2013 (Thousands of shares) TOPIX (Tokyo stock price index) TOPIX (Tokyo 09/4 09/4 Stock price and trading volume from July 16, 2013 are those listed on the Tokyo Stock those listed on the Tokyo July 16, 2013 are Stock price and trading volume from those listed on the Osaka Securities Exchange. Exchange; prior to this date are

0 0

9,000 6,000 3,000 6,000 4,500 3,000 1,500 Yearly High and Low Prices Yearly Trading Volume Volume Trading Stock Price Range 12,000 Established Paid-in Capital Number of Shareholders Stock Exchange Listings Corporate Headquarters High (yen) 3,195Notes 1: Calendar years. 3,445 2: for the period to the end of July. are Stock prices for 2014 3: 3,655 5,050 Low (yen) 2,694 2,731 2,778 3,330 Ticker Code Agent Transfer Major Offices Manufacturing Plants Laboratory Research Number of Employees Issued Number of Shares Monthly basis Monthly basis

As of March 31, 2014 31, As of March Corporate Information / Stock Information / Stock Information Corporate Business Bases As of August 2014

Plants and Laboratory

Noto Plant Shiga Product Supply Center Tampere Plant 2-14, Shikinami, Houdatsushimizu-cho, 348-3, Aza-suwa, Oaza-shide, Taga-cho, Niittyhaankatu 20, P.O. Box 33, Hakui-gun, Ishikawa 929-1494, Japan Inukami-gun, Shiga 522-0314, Japan FIN-33721 Tampere, TEL: +81-767-29-2666 FAX: +81-767-29-4233 TEL: +81-749-48-2900 FAX: +81-749-48-2901 TEL: +358-3-284-8111 FAX: +358-3-318-1900

Suzhou Plant Nara Research and Development Center No. 169 Tinglan Road, Suzhou Industrial Park, 8916-16, Takayama-cho, Ikoma-shi, Nara Jiangsu Province 215026, P.R.C. 630-0101, Japan TEL: +86-512-6295-7500 FAX: +86-512-6295-7800 TEL: +81-743-79-4501 FAX: +81-743-79-4521

90 Santen Pharmaceutical Co., Ltd. Annual Report 2014 Business Bases 91 Annual Report 2014 Business Administration of pharmaceutical for and business promotion affairs the Santen Group within the ASEAN region Production, marketing, clinical Production, development of pharmaceuticals Research, development, production, production, development, Research, marketing of pharmaceuticals development, Research, marketing of pharmaceuticals and medical devices Development, production, Development, production, marketing of medical devices Centralization of financial controls operations for European Research, development, production, development, production, Research, pharmaceuticals and marketing of medical devices Cleaning of antidust and sterilized clothing American Holding company for North development businesses and business Marketing support of pharmaceuticals Marketing, clinical development of pharmaceuticals Marketing of pharmaceuticals Pharmaceutical market research Business development, planning, product marketing of pharmaceuticals Clinical development of pharmaceuticals and business development Santen Pharmaceutical Co., Ltd. Co., Pharmaceutical Santen 5743 Thornwood Drive, Goleta, California 93117, U.S.A. +1-805-964-3065 TEL: +1-805-683-3851 FAX: Herikerbergweg 238, Zuidoost, 1101CM Amsterdam Fontaine, Genavenir IV, 1 rue Pierre F-91058 Evry cedex, +33-1-69-87-40-30 TEL: +33-1-69-87-40-20 FAX: Niittyhaankatu 20, P.O. Box 33, Niittyhaankatu 20, P.O. Finland FIN-33721 Tampere, +358-3-318-1900 TEL: +358-3-284-8111 FAX: No. 216, Raheja Chambers, 12 Museum Road, 560 001, Bangalore +91-80-4932-3799 TEL: +91-80-4932-3700 FAX: Solna torg 3, SE-17145 Solna, +46-8-83-4145 TEL: +46-8-83-4140 FAX: 169 Tinglan Road, Suzhou Industrial Park, No. 215026, P.R.C. Jiangsu Province +86-512-6295-7800 TEL: +86-512-6295-7500 FAX: 25-gil, Yeoksam-dong, 35, Yeoksam-ro 3F, KCUBE Tower Gangnam-gu, Seoul, 135-921, Korea +82-2-754-2929 TEL: +82-2-754-1434 FAX: South Rd., No. 57, Sec. 2, Tun-Hwa 16F, R.O.C. 10681, , Taipei +886-2-2700-1730 TEL: +886-2-2700-1553 FAX: Erika-Mann-Strasse 21 80636 Munchen, +49-89-848078-60 TEL: +49-89-848078-0 FAX: Grand Front Osaka Tower A, Osaka Tower Grand Front Japan Kita-ku, Osaka 530-8552, 4-20 Ofuka-cho, +81-6-6328-5082 TEL: +81-6-6321-7000 FAX: Inukami-gun, Taga-cho, 348-3, Aza-suwa, Oaza-shide, Shiga 522-0314, Japan +81-749-48-2239 TEL: +81-749-48-2234 FAX: Suite 1600, Emeryville, 2100 Powell Street, California 94608, U.S.A. +1-510-655-5682 TEL: +1-415-268-9100 FAX: 2100 Powell Street, Suite 1600, Emeryville, Suite 1600, Emeryville, 2100 Powell Street, CaliforniaU.S.A. 94608, One Raffles Place, Level 24 Tower 1, One Raffles Place, Level 24 Tower 1 Raffles Place 048616, +65-6408-0601 TEL: +65-6408-0573 FAX: Suit 1206B, TOWER W3, Oriental Plaza, No. 1, Dong Cheng District, Beijing 100738, P.R.C. East Chang An Ave., +86-10-8515-1020 TEL: +86-10-8515-1515 FAX: Unit 1406, Fl.14, Empress Tower, 138-142 Hai Ba Trung, Tower, Unit 1406, Fl.14, Empress District 1, HCMC, Vietnam Dakao Ward, +84-8-3824-2586 TEL: +84-8-3824-2585 FAX: Santen Holdings U.S. Inc. Santen Holdings U.S. Ho Chi Minh City Representative Office Ho Chi Minh City Representative Beijing Representative Office Beijing Representative Taiwan Santen Pharmaceutical Co., Ltd. Taiwan Santen Pharmaceutical Asia Pte. Ltd. Santen India Private Limited Santen Pharmaceutical () Co., Ltd. Santen Pharmaceutical Co., Ltd. Santen Pharmaceutical Korea Santen GmbH SantenPharma AB Santen Oy Santen S.A.S. Santen Inc. Science, Inc. Advanced Vision Santen Holdings EU B.V. Claire Co., Ltd. Claire Corporate Headquarters Corporate Headquarters and Subsidiaries Headquarters Corporate Other Office