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Product Name CAS# Cat# Purity Lead time 2-Amino-3-bromo-6-icoline 126325-46-0 221960 97%min 4 weeks 4-Chloro-2-fluorobromobenzene 1996-29-8 98503 98%min 15days 1-Bromo-5-fluoropentane 407-97-6 82007 99%min In stock 1-Bromo-3-fluoropropane 352-91-0 11623 98%min In stock200g 2-Bromophenylboronic acid 244205-40-1 421532 >98.5% 3 weeks 3-Amino-4-methylbenzoic acid 2458-12-0 36589 NLT >98.5% In stock (2-Chloro-3-pyridinyl)methanol 42330-59-6 707418 98% In stock 6-Mercapto-1-hexanol 1633-78-9 778009 98% <3 weeks Domiphen bromide 538-71-6 271226 99% In stock 4-Hydroxypyrimidine 4562-27-0 500772 98%min <3 weeks 5-(Trifluoromethyl)picolinonitrile 95727-86-9 840879 98% 12 days 5-Bromopyrimidine 4595-59-9 53640 99% In stock Terbuthylazine 5915-41-3 315253 98%min In stock 500kg 3-Bromo-4-fluoronitrobenzene 701-45-1 B57368 98%min In stock Silver trifluoromethanesulfonate 2923-28-6 57655 99% In stock Chondroitin 6-sulfate sodium salt 12678-07-8 224244 98%min In stock Ethyl 2-methyloxazole-4-carboxylate 10200-43-8 C129856 >97% <3 weeks Ethyl ethoxymethylene-3-oxo-4,4,4-trifluorobutyrate 571-55-1 B171944 98%min <10days N-Boc-4-Hydroxylmethylene-piperidine 123855-51-6 B100290 99% <3 weeks (4R)-1-(tert-Butoxycarbonyl)-4-hydroxy-D-proline 135042-12-5 B141253 98%min <15 days Isopropylhydrazine hydrochloride 16726-41-3 B432671 98% In stock 2-Methyl-1H-benzimidazole-5-carboxylic acid 709-19-3 B341851 98.5%min -stock Cyclohexanecarboxaldehyde 2043-61-0 B133242 98%min In stock S-2-Hydroxy-4-methylvaleric acid 13748-90-8 B298813 98%min In stock Tetrahydrofuran-3-amine 88675-24-5 B682436 98.5%min In stock Osteltamivir phosphate 204255-11-8 B119221 99% In stock Methyl 2-methylnicotinate 65719-09-7 B765701 98%min In stock 3,5-Dimethyl-4-isoxazolylboronic acid 16114-47-9 B89923 98%min 100g in stock 4-Methyloctanoic acid 54947-74-9 B74602 >97% In stock 3-Chloro-1,1-diethoxypropane 35573-93-4 B294494 80%min In stock 2-Amino-6-methoxypyrazine 6905-47-1 B59429 >95% 3 weeks N-Phenyl-bis(trifluoromethanesulfonimide) 37595-74-7 B89550 98%min In stock 3-Fluoro-4-morpholinoaniline 93246-53-8 B698428 99%min In stock 200kg Promethazine hydrochloride 58-33-3 B25983 99%min In stock 3-Cyclopenten-1-ol 14320-38-8 B38825 >97% In stock 4,7-Diphenyl-1,10-phenanthroline 1662-01-7 B707550 98% In stock 1-(o-Tolyl)piperazine 39512-51-1 B458673 98% In stock Sodium dibutyldithiocarbamate 136-30-1 B84800 40.90% In stock 1ton N-(2-(Diethylamino)ethyl)-5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxamide 356068-86-5 B484863 >98% 3-4 weeks Ethyl 3-oxo-4-phenylbutanoate 718-08-1 B99162 >96% <4weeks Diphenyl carbonate 102-09-0 B690491 98.5%min In stock 7H-Pyrrolo[2,3-d]pyrimidine-2,4-diol 39929-79-8 B233427 97%min In stock 4-Aminophenethyl alcohol 104-10-9 463332 98%min In stock Deflazacort 14484-47-0 B705963 98.5%min In stock (R)-2-Methyl-CBS-oxazaborolidine 112022-83-0 63916 1.0 M solution in toluene In stock 2-Bromobenzo[9,10]phenanthrene 19111-87-6 B491693 >97% 9 days 2,6-Dihydroxybenzoic acid 303-07-1 209110 >99% In stock Hexadecyltrimethylammonium bromide 57-09-0 743258 99%min In stock N-Boc-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester 286961-14-6 290758 98%min In stock Sunitinib malate 341031-54-7 131216 >99% In stock 5-Chloro-2-methoxybenzoic acid 3438-16-2 24205 99%min In stock 1,1,1,3,3,3-Hexafluoro-2-propanol 920-66-1 251829 99.90% In stock 4-Aminomorpholine 4319-49-7 686189 98%min In stock 2-Nitrobenzyl bromide 3958-60-9 78950 98%min In stock Dyclonine 586-60-7 475550 99% In stock DL-alpha-Phenylglycine 341659 420201 99%min In stock 4-Hydroxyphenethyl alcohol 501-94-0 227235 99%min In stock 5-Fluoroisoquinoline 394-66-1 27473 >97% 30 days 10H-Pyrido(3,2-b)(1,4)benzothiazine 261-96-1 875186 >97% In stock Calcium beta-hydroxy-beta-methylbutyric acid 135236-72-5 B04025 99%min In stock 1,2,3-Trimethylbenzene 526-73-8 C53732 >97% In stock Povidone-iodine 25655-41-8 121625 Nitrogen content>10.7% In stock Cyclopropylmethyl bromide 7051-34-5 194915 >97%min In stock Indeloxazine HCl 65043-22-3 481435 98%min In stock 3-Ethynylimidazo[1,2-b]pyridazine 943320-61-4 517133 98%min <30days H-D-Dap(Boc)-OMe(HCL form) 363191-25-7 346117 99% 3 weeks 4-Acetylbutyric acid 448671 96532 >98% In stock cis-2-Phenyl-1,3-dioxan-5-ol 4141-19-9 235589 >98% In stock Ethyl 3-cyclopentene-1-carboxylate 21622-01-5 386563 >97% Promptly 4-Iodobenzoic acid 619-58-9 374673 >98% In stock Mixed Octanamide/Decanamide - 105064 99%min In stock N,N-Dimethylcapramide 14433-76-2 34091 99%min In stock 3-HYDROXYPROPIONIC ACID 503-66-2 711580 99%min In stock 4-Pyridineboronic acid 1692-15-5 215144 98%min 3,5-Dichlorobenzyl alcohol, 60211-57-6 75209 98% 15 days 1-(2-Amino-4-bromophenyl)ethanone 123858-51-5 13865 >97% 4 weeks 1-(2-Amino-5-bromophenyl)ethanone 29124-56-9 518718 >95% 3 weeks (R)-(-)-1,1'-Binaphthyl-2,2'-diyl hydrogen phosphate 39648-67-4 105632 99%min In stock tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate 198904-85-7 547332 99% In stock 3-Fluoro-4-boc-piperidinone 211108-50-8 561757 >97% 4 weeks 1,3-Dimethylbarbituric acid 769-42-6 15617 99% In stock Dimethyl (2-oxopropyl)phosphonate 4202-14-6 39733 >95% In stock ETHYL 4-CHLOROBUTYRATE 3153-36-4 113034 99% In stock 13472-00-9 13472-00-9 14159 98%(HCL) 3 weeks 13472-00-9 13472-00-9 14159 98%(Base) 3 weeks Benzenesulfonyl chloride 98-09-9 89793 98%min In stock 1,2,4-Triazole sodium derivative 41253-21-8 23846 98%min In stock 3,5-Dichlorobenzenesulfonyl chloride 705-21-5 23846 98%min 2 weeks Linezolid 165800-03-3 26433 99% In stock 3-HEXYLTHIOPHENE 1693-86-3 50288 99% In stock 4-Hydroxyphenylacetic acid 156-38-7 41971 99%min In stock (R)-tert-Butyl 3-(methylamino)pyrrolidine-1-carboxylate 199336-83-9 69399 98%min <4 weeks 4,6-Dichloropyrimidine 1193-21-1 37510 99% <4 weeks N-Methoxy-N-methylacetamide 78191-00-1 58209 99%min In stock N-Iodosuccinimide 516-12-1 74944 99.50% In stock 4,4'-Diaminostilbene-2,2'-disulfonic acid 81-11-8 886392 95%min In stock Bosentan 147536-97-8 D06286 99%min In stock 4-Chloro-1H-pyrazolo[3,4-d]pyrimidine 5399-92-8 20899 98%min 2 weeks 2-Aminonicotinic acid 5345-47-1 86280 98%min In stock 4-Pyridylmethylamine 3731-53-1 34825 98%GC In stock Phthalimide 85-41-6 70679 99%min In stock Boc-L-Ser(tBu)-OH 13734-38-8 32823 98%min In stock 2-Methyl-3-biphenylmethyanol 76350-90-8 725359 99%min In stock 2-Methoxy-5-nitroaniline 99-59-2 943412 98%min 3-4 weeks (-)-Sparteine sulfate pentahydrate 1556278 7902730 98%min In stock 3-Bromo-1-(trimethylsilyl)-1-propyne, 38002-45-8 522343 97%+ In stock tert-Butyl methylcarbamate 16066-84-5 110732 96%+ 2 weeks 1-Bromo-3-phenylpropane 637-59-2 908652 98%min <30days Cobicistat 1004316-88-4 848111 98%min In stock 3-(Bromomethyl)phenol 74597-04-9 74502 98%min 4 weeks Methyl 6-chloronicotinate 73781-91-6 841027 98%min <4 weeks p-Toluenesulfonic anhydride 4124-41-8 193852 99%min Stock 4-Chlorobenzenesulfinic acid sodium salt hydrate 14752-66-0 964462 98%(GC) In stock 1-(5-Bromo-2-fluorophenyl)ethanone 198477-89-3 29489 98%min 3-4 weeks 3-Chloropyridine 626-60-8 38196 99% In stock 2-Hydroxy-5-iodopyridine 13472-79-2 442881 >98% Stock 4 kg Quinoline-2-boronic acid 745784-12-7 9756659 >97% In stock 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 761446-44-0 1284756 99% In stock 3-Aminophenol 591-27-5 482337 99.50%min In stock 3-(Bromomethyl)-1,2-benzisoxazole 37924-85-9 867831 98%min 4-5 weeks O-Benzyl-L-serine 4726-96-9 652712 98%min 2-3 weeks 7-Fluoroindole 387-44-0 564856 99% In stock Methyl 3-bromoisonicotinate 59786-31-1 348610 >97% 3-4 weeks 3-Chloro-4-methoxyaniline 5345-54-0 454326 >98.5% In stock 5kg 3-Fluoro-4-methylbenzonitrile 170572-49-3 393607 99%min In stock Sodium tetrafluoroborate 13755-29-8 700231 99%min In stock 1,3-Cyclopentanedione 3859-41-4 1412737 98%min In stock 1-Methylindole 603-76-9 245870 99%min(GC) In stock 1-Bromo-3-fluoro-4-(trifluoromethoxy)benzene 105529-58-6 660631 99%min In stock 1kg 4-Amino-3-methoxybenzonitrile 177476-76-5 558817 98%min <4 weeks 3-Chloro-4-methoxybenzaldehyde 1097074 488152 99%min 4 weeks Triethylene glycol monobenzyl ether 55489-58-2 920962 98%min 3 weeks 12-Crown-4 294-93-9 82925 98%min 4-6weeks 1-Cyano tetralin 56536-96-0 643678 98.5%min In stock 1H-Imidazole-1-sulfonyl azide hydrochloride 952234-36-5 600113 98%min Stock 100g CAS [845614-11-1] 845614-11-1 305305 98%min <6 weeks 1-Boc-2-methyl-4-piperidinone 190906-92-4 488204 >97% 3-4 weeks http://berrchem.com [email protected] We provide premium tailor-made products to fit each customer need ur vision is to help the global customers to shorten their drug development cycle and reduce development cost through our excellent quality and highly efficient outsourcing service Gibberellin A4 468-44-0 665213 >90% <10 days 4-Iodopyridine 15854-87-2 84146 99.5%min <4 weeks 4,4'-Oxybis(benzoic acid) 2215-89-6 951941 99% In stock Methyl 4-(2-methoxy-2-oxoethyl)benzoate 52787-14-1 511609 99%min In stock 2-Bromo-6-fluorobenzotrifluoride 261951-85-3 900361 98% 3 weeks Gibberellic acid 77-06-5 807446 Gibberellic content:90%min <7 days 2,6-Diazaspiro[3.3]heptane 174-77-6 2379962 >97% stock 4-(Trifluoromethoxy)benzyl cyanide 49561-96-8 749567 99%min In stock Methyl 3-oxo-3-phenylpropanoate 614-27-7 351885 >97% 4 weeks 1-Bromo-5-fluoro-4-methoxy-2-nitrobenzene 661463-13-4 912279 >97 <4 weeks 3,5-Bis(trifluoromethyl)iodobenzene 328-73-4 119491 98%min <4 weeks 4-Hydroxy-3-(trifluoromethyl)benzaldehyde
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    Multi-Class Determination of 64 Illicit Compounds in Dietary Supplements Using Liquid Chromatography–Tandem Mass Spectrometry

    molecules Article Multi-Class Determination of 64 Illicit Compounds in Dietary Supplements Using Liquid Chromatography–Tandem Mass Spectrometry Dasom Shin, Hui-Seung Kang *, Hyungsoo Kim and Guiim Moon New Hazardous Substances Division, Department of Food Safety Evaluation, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Osong, Cheongju 28159, Korea; [email protected] (D.S.); [email protected] (H.K.); [email protected] (G.M.) * Correspondence: [email protected] Received: 11 August 2020; Accepted: 17 September 2020; Published: 24 September 2020 Abstract: In this work, liquid chromatography–tandem mass spectrometry (LC-MS/MS) method was developed and validated for screening and confirmation of 64 illicit compounds in dietary supplements. The target compounds were illegally used pharmaceutical drugs, prohibited compounds, and not authorized ingredients for different therapeutics (sexual enhancement, weight loss, muscular strengthening, and relaxing products). The validation procedure was performed to evaluate selectivity, linearity, limit of detection (LOD), limit of quantification (LOQ), accuracy, and precision according to the Association of Official Analytical Chemists guidelines. The linearity was >0.98 in the range of 1 1 0.5–200 µg L− . The LOQs were in the range 1–10 µg kg− for all target compounds. The accuracy (expressed as recovery) was 78.5–114%. The precision (expressed as the relative standard deviation) was below 9.15%. The developed method was applied for the determination of illicit compounds in dietary supplements collected from websites. As a result, the total detection rate was 13.5% (27 samples detected in 200 samples). The concentrations of detected samples ranged from 0.51 1 to 226 mg g− .
  • PROVISIONAL PEER-REVIEWED TOXICITY VALUES for VANADIUM and ITS SOLUBLE INORGANIC COMPOUNDS OTHER THAN VANADIUM PENTOXIDE (CASRN 7440-62-2 and Others)

    PROVISIONAL PEER-REVIEWED TOXICITY VALUES for VANADIUM and ITS SOLUBLE INORGANIC COMPOUNDS OTHER THAN VANADIUM PENTOXIDE (CASRN 7440-62-2 and Others)

    EPA/690/R-09/070F l Final 9-30-2009 Provisional Peer-Reviewed Toxicity Values for Vanadium and Its Soluble Inorganic Compounds Other Than Vanadium Pentoxide (CASRN 7440-62-2 and Others) Derivation of Subchronic and Chronic Oral RfDs Superfund Health Risk Technical Support Center National Center for Environmental Assessment Office of Research and Development U.S. Environmental Protection Agency Cincinnati, OH 45268 Commonly Used Abbreviations BMD Benchmark Dose IRIS Integrated Risk Information System IUR inhalation unit risk LOAEL lowest-observed-adverse-effect level LOAELADJ LOAEL adjusted to continuous exposure duration LOAELHEC LOAEL adjusted for dosimetric differences across species to a human NOAEL no-observed-adverse-effect level NOAELADJ NOAEL adjusted to continuous exposure duration NOAELHEC NOAEL adjusted for dosimetric differences across species to a human NOEL no-observed-effect level OSF oral slope factor p-IUR provisional inhalation unit risk p-OSF provisional oral slope factor p-RfC provisional inhalation reference concentration p-RfD provisional oral reference dose RfC inhalation reference concentration RfD oral reference dose UF uncertainty factor UFA animal to human uncertainty factor UFC composite uncertainty factor UFD incomplete to complete database uncertainty factor UFH interhuman uncertainty factor UFL LOAEL to NOAEL uncertainty factor UFS subchronic to chronic uncertainty factor i FINAL 9-30-2009 PROVISIONAL PEER-REVIEWED TOXICITY VALUES FOR VANADIUM AND ITS SOLUBLE INORGANIC COMPOUNDS OTHER THAN VANADIUM PENTOXIDE (CASRN 7440-62-2 and others) Background On December 5, 2003, the U.S. Environmental Protection Agency's (U.S. EPA) Office of Superfund Remediation and Technology Innovation (OSRTI) revised its hierarchy of human health toxicity values for Superfund risk assessments, establishing the following three tiers as the new hierarchy: 1) U.S.
  • Stimulant Medications and Supplements: Clinical Implications for the Sports Medicine Provider Collaborative Solutions for Safety in Sport

    Stimulant Medications and Supplements: Clinical Implications for the Sports Medicine Provider Collaborative Solutions for Safety in Sport

    Stimulant Medications and Supplements: Clinical Implications for the Sports Medicine Provider Collaborative Solutions for Safety in Sport Francis G. O’Connor, MD, MPH, COL, MC, USA Professor and Chair, Military and Emergency Medicine Uniformed Services University of the Health Sciences DISCLOSURE . I have no relevant financial disclosures in reference to this lecture. That being said, I am a physician in the US Army, and work for the DoD. My opinions and assertions contained herein are private views and are not to be construed as official or as reflecting the views of the U.S. Army Medical Department , Uniformed Services University or the Department of Defense at large. Case Presentation 1 . 25 y/o soldier presents to the sports medicine clinic for heat tolerance testing and a return to duty assessment; . He sustained an exertional heat stroke (EHS) during Special Forces accession. Soldier was acclimatized with no history of EHS; he had been using a pre- workout stimulant. Case Presentation 2 . 25 y/o soldier presents to the medical aid station complaining of palpitations, agitation and insomnia. He has sinus tachycardia on the monitor and reports regular use of Red Bull and caffeine gum. Unit is requesting guidance on strategies for sleep. Case Presentation 3 . A warfighter contacts the Human Performance Resource Center looking for help. Recently using a new pre- workout supplement to enhance training. Unfortunately the soldier “popped positive” on a recent urine drug screen. Case Presentation 4 . Alison is a 19 y/o transfer female basketball player. She states she has a personal history of ADHD and would like to renew her prescription for Ritalin.
  • 1 Abietic Acid R Abrasive Silica for Polishing DR Acenaphthene M (LC

    1 Abietic Acid R Abrasive Silica for Polishing DR Acenaphthene M (LC

    1 abietic acid R abrasive silica for polishing DR acenaphthene M (LC) acenaphthene quinone R acenaphthylene R acetal (see 1,1-diethoxyethane) acetaldehyde M (FC) acetaldehyde-d (CH3CDO) R acetaldehyde dimethyl acetal CH acetaldoxime R acetamide M (LC) acetamidinium chloride R acetamidoacrylic acid 2- NB acetamidobenzaldehyde p- R acetamidobenzenesulfonyl chloride 4- R acetamidodeoxythioglucopyranose triacetate 2- -2- -1- -β-D- 3,4,6- AB acetamidomethylthiazole 2- -4- PB acetanilide M (LC) acetazolamide R acetdimethylamide see dimethylacetamide, N,N- acethydrazide R acetic acid M (solv) acetic anhydride M (FC) acetmethylamide see methylacetamide, N- acetoacetamide R acetoacetanilide R acetoacetic acid, lithium salt R acetobromoglucose -α-D- NB acetohydroxamic acid R acetoin R acetol (hydroxyacetone) R acetonaphthalide (α)R acetone M (solv) acetone ,A.R. M (solv) acetone-d6 RM acetone cyanohydrin R acetonedicarboxylic acid ,dimethyl ester R acetonedicarboxylic acid -1,3- R acetone dimethyl acetal see dimethoxypropane 2,2- acetonitrile M (solv) acetonitrile-d3 RM acetonylacetone see hexanedione 2,5- acetonylbenzylhydroxycoumarin (3-(α- -4- R acetophenone M (LC) acetophenone oxime R acetophenone trimethylsilyl enol ether see phenyltrimethylsilyl... acetoxyacetone (oxopropyl acetate 2-) R acetoxybenzoic acid 4- DS acetoxynaphthoic acid 6- -2- R 2 acetylacetaldehyde dimethylacetal R acetylacetone (pentanedione -2,4-) M (C) acetylbenzonitrile p- R acetylbiphenyl 4- see phenylacetophenone, p- acetyl bromide M (FC) acetylbromothiophene 2- -5-