Anti-YARS monoclonal antibody, clone ZBS6I19 (DCABH-9019) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Mouse monoclonal to Tyrosyl tRNA synthetase

Antigen Description Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).

Immunogen Recombinant human YARS fragment

Isotype IgG1

Source/Host Mouse

Species Reactivity Mouse, Rat, Human

Clone ZBS6I19

Purity Protein G purified

Purification This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.

Conjugate Unconjugated

Applications WB, IP, ICC, Dot Blot

Positive Control HeLa cells and cell lysate and NIH3T3 cell lysate.

Format Liquid

Size 100 μg

Buffer Preservative: 0.05% Sodium Azide; Constituents: 1% BSA, PBS, 3mM Potassium chloride, 140mM Sodium chloride, 1.5mM KH2PO4, 8.0mM Na2HPO4, pH 7.4

Preservative 0.05% Sodium Azide

Storage Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved INFORMATION

Gene Name YARS tyrosyl-tRNA synthetase [ Homo sapiens ]

Official Symbol YARS

Synonyms YARS; tyrosyl-tRNA synthetase; tyrosine--tRNA ligase, cytoplasmic; tyrosine tRNA ligase 1; cytoplasmic; tyrRS; YRS; YTS; tyrosyl--tRNA ligase; tyrosine tRNA ligase 1, cytoplasmic; tyrosyl- tRNA synthetase, cytoplasmic; TYRRS; CMTDIC;

Entrez Gene ID 8565

Protein Refseq NP_003671

UniProt ID P54577

Chromosome Location 1p35.1

Pathway Aminoacyl-tRNA biosynthesis, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, conserved biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, conserved biosystem; Cytosolic tRNA aminoacylation, organism-specific biosystem; , organism-specific biosystem; tRNA Aminoacylation, organism-specific biosystem;

Function ATP binding; interleukin-8 receptor binding; ligase activity; nucleotide binding; signal transducer activity; tRNA binding; tyrosine-tRNA ligase activity;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved