EUROPEAN JOURNAL of GENERAL MEDICINE An official Journal of the Health Science Research Society

The journal is currently indexed/included in Bioline International, Chemical Abstracts Service, CINAHL, EBSCO Information System, Swets Information Services Citation Index and Index Copernicus.

ORIGINAL ARTICLE

SChange in Smoking Habits and Contribution of Physicians to Smoking Cessation in Patients with Nonmuscle-Invasive Bladder Cancer Kalkan et al. The Link Between Cardio-Metabolic Risk Factors, Serum sIL-2R and Echocardiography Data in Type 2 Diabetes Al-Nimer et al. Non-Invasive Evaluation of Liver Fibrosis Using Real-Time Elastography and Comparison of Intercostal and Subcostal Approaches Uslu et al. Knowledge Level of Hepatitis B and its Prevalance in Policemen Working in Adiyaman Kölgelier et a. Role of ADDUCIN Gly460Trp, ACE I/D and AGT M235T Gene Polymorphisms in Genetic Susceptibility to Diabetic Nephropathy Sancakdar et al. Success Rates of Pharmacological Therapies Used for Smoking Cessation and Factors that Affect Smoking Cessation Rates Tanrıverdi et al. Epicardial Fat Thickness and its Association with Cardiovascular Risk in Patients with Type 2 Diabetes Mellitus Akyürek et al. Morphological Nasal Changes Associated with Rapid Maxillary Expansion Uysal et al. An Investigation of the Risk Factors and Prevalence of Alzheimer's Disease in the Eastern Region of Turkey Ertekin et al. Assessment of Metabolic Syndrome in Patients with Migraine in Central Anatolia Celikbilek et al.

CASE REPORTS Well-Differentiated Neuroendocrine Carcinoma of the Extrahepatic Biliary Duct Köksal et al. A Successful Live Twin Birth by In vitro Fertilization in an Untreated Patient with Silent Genital Tuberculosis Inal and Inal Hypokalemic Periodic Paralysis Due To Distal Renal Tubular Acidosis

V Gündüz et al. o IgA Nephropathy in the Course of Sarcoidosis with Multi-Systemic Involvement

l u Elcioglu et al.

m An Unclear Anemia in an Elderly Subject with Aortic Stenosis

e

1 Valerio Massimo Magro

2 Simultaneous Bilateral Secondary Pneumothorax

N

u Oncel et al. m Total Gastrectomy Under Epidural Anesthesia in a High Risk Patient

b

e Polat et al. r Vulvar Chancroid

3

Y Ulubay et al. e Giant Cell Tumor of Distal Radius Treated by En-Bloc Resection and Reconstruction

a r by Non Vascularized Fibular Graft

2

0 Malu et al. 1 REVIEW

5 Is PSA Still the Best Marker in Diagnosis and Monitoring of Prostate Cancer? Akbaş et al. Volume 12 Number 3 Year 2015 EUROPEAN JOURNAL of GENERAL MEDICINE An International Peer-Reviewed Journal in the Field of General Medicine

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Aims and Scope EUROPEAN JOURNAL of GENERAL MEDICINE (ISSN 1304-3897 ) is an English multidisciplinary peer-re- viewed medical journal publishing articles in the fields of general medicine. EUROPEAN JOURNAL OF GENERAL MEDICINE is published quarterly (January, April, July and October) by the Society of Health Sciences Researchs, Turkey.

EUROPEAN JOURNAL of GENERAL MEDICINE encourages submissions from all authors throughout the world. Manuscripts are judged by two experts solely on the basis of their contribution of original data, ideas and their presentation. All manuscripts must comply with Instructions to Authors. The following articles will be considered for publication: editorials, original and review articles, brief reports, case reports, letters to the editor, and book reviews.

Submitted manuscripts must not have been published, accepted for publication or be under con- sideration elsewhere. Investigation on human subjects should conform to the guidelines noted in the World Health Organization Chronicle 1976; 30: 360-362.

All articles will be critically reviewed by the editor and members of the editorial or advisory board of the journal within 2 months, but longer delays are sometimes unavoidable. Full details may be found in the section of Instructions to Authors at the end of this issue.

The free-full text of the journal is available from online system. Please visit the journal website (www.ejgm.org).

Indexing and Abstracting Services: The journal is currently indexed/included in Bioline International, EBSCO, CINAHL, Scopus, EMBASE, Index Copernicus, Swets Information Services, TUBITAK ULAKBIM Turk- ish Medical Database, Turkey Citation Index and Chemical Abstracts Service. EUROPEAN JOURNAL of GENERAL MEDICINE An International Peer-Reviewed Journal in the Field of General Medicine www.ejgm.org

INSTRUCTION TO AUTHORS (8) Number the title page as 1, abstract page as 2, and so forth. (Leave the second title page) Type on 22 28 MANUSCRIPTS are received with the understanding that cm (8.5 11 inch) paper, on 1 side only of each sheet, they are submitted solely to THE EUROPEAN JOURNAL double-spaced (including references) with at least 25- OF GENERAL MEDICINE®, that upon submission, they mm (1-inch) margins. become the property of the Publisher, that the work has not been previously published, and that the data The second title page, which omits the names and in the manuscript have been reviewed by all authors, institutions of authors, gives the Editor in Chief the who agree with the analysis of the data and the option of acquiring blinded or nonblinded reviews. conclusions reached in the manuscript. The Publisher References to the institution in the text or to the reserves copyright and renewal on all published author’s previous work in the Reference section must material, and such material may not be reproduced be deleted or written in a manner that prevents without the written permission of the Publisher. identification of authors and institution. Label figures Statements in articles are the responsibility of the with the manuscript title rather than the authors’ authors. Only papers in English will be considered for names so that blinded reviews can be solicited. publication. Authors should state which type of review they wish in the cover letter. ADDRESS MANUSCRIPTS TO: Manuscripts should be submitted online at www.ejgm.org. TITLE PAGE AND ABSTRACT: For the complete title page, include the full first or middle and last names Please include the corresponding author’s e-mail, of all authors. List the institution and address from phone and fax number. The cover letter should which the work originated, and provide information state the significance and uniqueness of the work about grant support if necessary. If work described is in the authors’ view. Several names and addresses supported by a grant from a pharmaceutical company, of nonlocal experts may be suggested who, in the that fact should be stated on the title page. Add at the authors’ view, could provide objective and informed bottom the phrase, “Address for reprints:” followed by reviews of their work. The names of investigators full name and address with zip code. Add a 2- to 5-word considered unlikely by the authors to give nonbiased running head. Limit the abstract to 200 words. List 3 reviews of their work also may be submitted. This to 5 key words for subject indexing at the end of the request is honored. abstract or Brief Communication.

INFORMED CONSENT AND ETHICS STYLE: Use appropriate subheadings throughout the body of the text, such as Methods, Results, and When reporting studies on human subjects, notice Discussion. Tables, figures, and references should be whether the protocols were in accordance with mentioned in numerical order throughout manuscript. the ethical standards of the related committee on Abbreviations are permitted, but no more than 3 per human experimentation (regional or institutional) manuscript, and then they must be used on every or with the 1975 Helsinki Declaration (including 1983 page of the manuscript after they are initially spelled revision). Include any Ethical Committee or Animal out (followed by the abbreviation) in both abstract Ethics Committee protocol numbers as warranted by and introduction. Abbreviations are usually limited to experimental design. terms in the manuscript’s title. Use generic names of drugs. Do not spell out any number, including Arrange the paper as follows: (1) title page, which those less than 10, except when used for opening should include the title, the full names and academic a sentence, but try not to begin sentences with degrees of the authors, and the institution and city numbers. Use symbols for less than (<), greater than and state or city and country from which the work (>) and percent (%). Indent paragraphs except the originated; (2) second title page, with only the title of first one in both abstract and introduction.Consult the article (page not numbered); (3) abstract; (4) text; the Uniform Requirements for Manuscripts Submitted (5) acknowledgment; (6) references; (7) figure legends; to Biomedical Journals, published in N Engl J Med EUROPEAN JOURNAL of GENERAL MEDICINE An International Peer-Reviewed Journal in the Field of General Medicine www.ejgm.org

1991; 324: 424-428. double-spaced. Number each table in Arabic numerals (Table 1, 2, etc.) and title each table. Identify in TRADE NAMES Non-proprietary (generic) names of alphabetical order at the bottom of the table all products should be used. If a brand name for a drug abbreviations used. When tabulating numbers of is used, the British or International non-proprietary patients, use no more than 2 lines, preferably only l line, (approved) name should be given. The source of per patient. Use a plus sign (+) to indicate “positive” or any new or experimental preparation should also be “present,” a zero (0) for “negative” or “absent,” and a given. REFERENCES: References should be limited to dash (-) for “no information available” or “not done.” those relating directly to the content of the paper. Do not use “yes” or “no” or “none.” Footnote symbols List all authors, year, volume, and inclusive pages must appear in this order: *, **, #, , , , §, , etc. for all journal references, and specific page numbers for all book references as shown below. Do not use BRIEF COMMUNICATIONS and CASE REPORTS: These periods after authors’ initials or after abbreviations should be limited to no more than 3 text pages (those for titles of journals. Check Index Medicus or N Engl J before the references but including the title page) and Med 1991;324:424-8 as cited above for journal titles 20 references. An abstract is not required. Subheadings and abbreviations. Personal communications and are not used. Provide a summary sentence at the end. unpublished observations do not constitute references, but may be mentioned within the text. Please note that READERS’ COMMENTS: The author who submits a all authors should be listed when six or less; when seven “letter” should provide a cover letter on his/her or more, list only the first three and add et al. Please do own stationery to the Editor in Chief stating why not use the footnote or endnote functions in your word the letter should be published. The letter (as well processing program. as references) should be typed, double-spaced, on a Journal: Vikse BE, Aasard K, Bostad L, Iversen BM. separate sheet of plain white paper and limited, with Clinical prognostic factors in biopsy-proven benign few exceptions, to 2 pages. Submit the original and nephrosclerosis. Nephrol Dial Transplant 2003;18:517-23. 2 copies. A title for the letter should be provided at the top of the page. At the end of the letter, the Chapter in Book: Davison AM, Cameron JS, Grünfeld writer’s full name, city, state and country should be JP, Kerr DNS, Ritz E, Winerals CG. Oxford Textbook of provided. The author’s title and institution should not Clinical Nephrology. In Williams G, ed. Mesengiocapillary be included. A letter concerning a particular article glomerulonephritis. New York: Oxford University Press, in the Journal must be received within 3 months of 1998: 591-613. the article’s publication.

Book: Danovitch GM. Handbook of Kidney REPRINTS: Price schedules and order cards for Transplantation. Boston: Little, Brown and Company reprints are mailed to the author upon publication (Inc.), 1996: 323-8 of the article. Individual reprints must be obtained through the author. FIGURES:Patients shown in photographs should have their identity concealed or should have given their PERMISSIONS: All inquiries regarding copyright material written consent to publication. Submit written from this publication should be directed to Health permission from the publisher and author to reproduce Sciences Researchs Society any previously published figures. Limit figures to the number necessary to present the message clearly. Do not use 3-D features and unnecessary gray shadings on simple bar charts. Identify at the end of each legend and in alphabetical order all abbreviations in the figure. The cost of color reproduction must be paid by the author.

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EDITOR-IN-CHIEF Cevdet Altinyazar

ASSOCIATE EDITORS Kürşat Uzun Mustafa Keleş Savaş Yılmaz Hakan Şenaran

EDITORIAL BOARD

Kadir ACAR, Turkey Hüseyin BAYRAMLAR, Turkey Tevfik ECDER, Turkey Abdülbaki AGBAŞ, USA Grant M. BAXTER, Scotland Aydın ECE, Turkey Canan AĞALAR, Turkey Henrik BIERING, llker ERCAN, Turkey Fatih AĞALAR, Turkey Gianluigi BISLERI, Italy Mehmet EREN, Turkey Suhail AHMAD, USA Said BODUR, Turkey Fikret ERGÜNGÖR, Turkey Fatih AKÇAY, Turkey M. Akif BÜYÜKBEŞE, USA Mehmet ERİKOĞLU, Turkey Ramazan AKÇAN, Turkey Roger W. BYARD, Australia Beyhan ERYONUCU, Turkey Fatih AKÇAY, Turkey Miktat BOZER, Turkey Alfio FERLITO, Italy Hakan AKILLI, Turkey Cem M. BÖRÜBAN, Turkey Fatma FİDAN, Turkey Hülya AKSOY, Turkey Kadir CEYLAN, Turkey Giampietro GASPARINI, Italy Salih AKSU, Turkey Ayşe CEFLE, Turkey Marc GENTILI, France Ömer AKYOL, Turkey Marcelo P. CAVALCANTI, Brazil Serdar GERGERLİOĞLU, Turkey Hişam ALAHDAB, Turkey Dave D. CHADEE, West Indies Georgia GIOULA, Mustafa ALDEMİR, Turkey Malay CHATTERJEE, India Faik GIRISKEN, Germany Süleyman ALICI, Turkey Francesko CORCIONE, Italy Hakkı GÖKBEL, Turkey Gernot S ALTEDORNEBURG, Germany Gerard CRINER, USA Cesare GRIDELLI, Italy Remzi ALTIN, Turkey Hüseyin ÇAKSEN, Turkey Fuat GÜRKAN, Turkey Cevdet ALTINYAZAR, Turkey Hakan ÇANKAYA, Turkey Ahmet GÜL, Turkey Kadri ALTUNDAĞ, Turkey Adnan ÇINAL, Turkey Ekrem GÜLER, Turkey Nicolino AMBROSINO, Italy Erdinç ÇİÇEK, Turkey Kenan GÜMÜŞTEKİN, Turkey Halil ARSLAN, Turkey Bektur DANIAROV, Germany Bülent GÜRLER, Turkey Fatih AYGÜN, Turkey Emile DARAI, France Muhammed GÜVEN, Turkey Recep AYGÜL, Turkey Kenan DEMİR, Turkey Galip GÜZ, Turkey Mustafa BAKIR, Turkey Reha DEMİREL, Turkey Naotaka HAMASAKI, Japan Derya BALBAY, Turkey Kadir DEMİRCAN, Turkey Hasan HERKEN, Turkey Francis W. BALLARDIE, UK Abdullah DOĞAN, Turkey Satoshi HIROHATA,Japan Metin BAŞARANOĞLU, Turkey Ekrem DOĞAN, Turkey David W. HOLT, UK Talantbek BATYRALIEV, Turkey Fatma DURSUN, Turkey Gregory G. HOMISH, USA Ali BAY, Turkey Haluk DÜLGER, Turkey Salih HOŞOĞLU, Turkey EUROPEAN JOURNAL of GENERAL MEDICINE An International Peer-Reviewed Journal in the Field of General Medicine

EDITORIAL BOARD

Haitham IDRISS,USA Bülent ORAN, Turkey Yaşar ŞEN, Turkey Andre KAHN, Belgium Serkan ÖZAKBAŞ, Turkey Hakan ŞENARAN, Turkey Shigeyuki KANO, Japan Nihal ÖZARAS, Turkey Önder TAN, Turkey Şemsettin KARACA, Turkey Orhan ÖZBEK, Turkey Orhan TARÇIN, Turkey İlhan KARACAN, Turkey Murat ÖZDEMİR, Turkey Servet TATLI, USA Saliha KARATAY, Turkey Hakan ÖZDENER, USA Turgut TEKE, Turkey Akın KAYA, Turkey Faruk ÖZER, Turkey Serdar TOKER, Turkey Mehmet KAYRAK, Turkey Hakan ÖZHAN, Turkey Aysun TOKER, Turkey Halil KIYICI, Turkey Mehmet ÖZKÖKELİ, Turkey Harun TOY, Turkey Aysel KIYICI, Turkey Önder ÖZTÜRK, Turkey Hatice TOY, Turkey İsmail KATI, Turkey Il-Kwon PARK, Republic of Korea İbrahim TUNCAY, Turkey Dmitry KAZAKOV, Markku PARTINEN, Finland Volkan TUZCU, USA Rumeyza KAZANCIOĞLU, Turkey Igor PERSHUKOV, Russia Aydn TÜRKMEN, Turkey Recep KEŞLİ, Turkey Mark A. PETERMAN, USA Serdar UĞRAŞ, Turkey Nicholas KIPSHIDZE, USA Joachim PFANNSCHMIDT, Germany Murat UNALACAK, Turkey Necmi KIYMAZ, Turkey Doris POPP, Germany Das N. UNDURTI, USA Abdulkadir KOÇER, Turkey Bruce E. POLLOCK, USA Efkan UZ, Turkey Hasan KOÇOĞLU, Turkey Listernick ROBERT, USA M. Sıddık ÜLGEN, Turkey Maeda KOUTAROU, Japan Lane M. ROBSON, USA Bünyamin ÜNAL, Turkey Rossen K. KOYTCHEV, Germany Mehmet E. SAKARYA, Turkey Mehmet ÜNLÜ, Turkey Sami KUÇUKŞEN, Turkey Ali SALLI, Turkey Ayhan VERİT, Turkey Tevfik KÜÇÜKKARTALLAR, Turkey Anatoliy SAMKO, Russia Michael V. VITIELLO, USA Han LI-KUN, Japan Oktay SARI, Turkey Hüseyin VURAL, Turkey Kevin J. LALIBERTE, USA İbrahim SARI, Turkey Peter WARK, UK Karoly LAPIS, Hungary Mustafa SARSILMAZ, Turkey Murat YAĞMURCA, Turkey Jean-ClaudeM LUBANDA,Czech Republic Mehmet SAYARLIOĞLU, Turkey İlhan YARGIÇ, Turkey Emin MADEN, Turkey Hayriye SAYARLIOĞLU, Turkey Ahmet YEŞİLDAĞ, Turkey Burkhard J. MANFRAS, Germany Otto SCHÜCK, Czech Republic Mehmet YAZICI, Turkey Valeri MASENKO, Russia Mehmet Ş. SEVER, Turkey Mehmet YAZICI, Turkey Muhammed A MEMON, Australia Alper SEVİNÇ, Turkey Köksal YUCA, Turkey Jaime M. MONTI, Uruguay M.Tuğrul SEZER, Turkey Müslüm YURTÇU, Turkey Megumi MATSUMOTO, Japan Maria T. SHIPKOVA, Germany Kadriye B. YÜKSEL, Turkey E. Michael MOLNAR, USA Neeru SINGH, India Zeki YILDIRIM, Turkey Alvaro Jose J. MONTIEL, Mexico Valentin SINITSYN, Russia Ramazan YILMAZ, Turkey Motohito N/A NAKAGAWA, Japan Aytekin SIR, Turkey Sinan YOL, Turkey Matthew NAUGHTON, Australia Ömer SOYSAL, Turkey Müslüm YURTÇU, Turkey Nobuyuki NEGORO, Japan Yalçın SOLAK, Turkey İsmail ZARARSIZ, Turkey Kemal ÖDEV, Turkey Hui SUI, Frederik J. ZIJLSTRA, Mehmet OKKA, Turkey Güven S. SUNAM, Turkey EUROPEAN JOURNAL of GENERAL MEDICINE An International Peer-Reviewed Journal in the Field of General Medicine

www.ejgm.org Eur J Gen Med 2015;12(2)

CONTENTS ORIGINAL ARTICLES Change in Smoking Habits and Contribution of Physicians to Smoking Cessation in Patients with Nonmuscle-Invasive Bladder Cancer 101 Mehmet Kalkan, Hakkı Uzun, Sadi Turkan, Coşkun Sahin, Fidan Fatma, Faruk Yencilek, Hakan Koyuncu The Link Between Cardio-Metabolic Risk Factors, Serum sIL-2R and Echocardiography Data in Type 2 Diabetes 104 Marwan SM Al-Nimer, Ismail I Hussein, Samir AH Al-Obaidi, Kasim Ibrahim Mohamed Non-Invasive Evaluation of Liver Fibrosis Using Real-Time Elastography and Comparison of Intercostal and Subcostal Approaches 109 Abdulaziz Uslu, Abdussamet Batur, Murat Bıyık, Saim Acıkgozoglu Knowledge Level of Hepatitis B and its Prevalance in Policemen Working in Adiyaman 114 Servet Kölgelier, Nazlım Aktuğ Demir, Lütfi Saltuk Demir, Serap Özçimen, Ahmet Çağkan İnkaya Role of ADDUCIN Gly460Trp, ACE I/D and AGT M235T Gene Polymorphisms in Genetic Susceptibility to Diabetic Nephropathy 118 Enver Sancakdar, Kadir Ateş, Dilara Kaman, Köksal Deveci, Yusuf Özkan, Necip İlhan Success Rates of Pharmacological Therapies Used for Smoking Cessation and Factors that Affect Smoking Cessation Rates 125 Hakan Tanrıverdi, Murat Altuntaş, Özgür Demir, Bilgen Begüm Afşar, Metin Çelikiz Epicardial Fat Thickness and its Association with Cardiovascular Risk in Patients with Type 2 Diabetes Mellitus 131 Ömer Akyürek, Duran Efe, Zeynettin Kaya Morphological Nasal Changes Associated with Rapid Maxillary Expansion 136 İsmail Önder Uysal, Berna Zorkun, Salim Yüce, Muhammet Birlik, Kerem Polat, Hasan Babacan An Investigation of the Risk Factors and Prevalence of Alzheimer’s Disease in the Eastern Region of Turkey 144 Ayfer Ertekin, Recep Demir, Gökhan Özdemir, Lütfi Özel, Ercan Özyıldırım, Hızır Ulvi

Assessment of Metabolic Syndrome in Patients with Migraine in Central Anatolia 152 Asuman Celikbilek, Elif Borekci, Mustafa Kozan, Mehmet Celikbilek CASE REPORTS Well-Differentiated Neuroendocrine Carcinoma of the Extrahepatic Biliary Duct 157 Hande Köksal, N. Serdar Uğraş, Bülent Uysal, M. Cem Börüban A Successful Live Twin Birth by In vitro Fertilization in an Untreated Patient with Silent Genital Tuberculosis 160 Hasan Ali Inal, Zeynep Hafiza Ozturk Inal Hypokalemic Periodic Paralysis Due To Distal Renal Tubular Acidosis 164 Ercan Gündüz, Yılmaz Zengin, Recep Dursun, Mustafa İçer, Mehmet Nezir Güllü, Hasan Mansur Durgun IgA Nephropathy in the Course of Sarcoidosis with Multi-Systemic Involvement 167 Omer Celal Elcioglu, Abdullah Ozkok, Ali Bakan, Yasemin Ozluk, Isin Kilicaslan, Aslihan Ak, Gul Erdal Donmez, Ali Riza Odabas An Unclear Anemia in an Elderly Subject with Aortic Stenosis 170 Valerio Massimo Magro Simultaneous Bilateral Secondary Pneumothorax 174 Murat Oncel,Guven Sadi Sunam,Huseyin Yıldıran Total Gastrectomy Under Epidural Anesthesia in a High Risk Patient 177 Erdal Polat, Necdet Fatih Yaşar, Tülin Akarsu, Cebrail Akyüz, Aziz Serkan Senger, Mustafa Duman, Sinan Yol Vulvar Chancroid 180 Mustafa Ulubay, Uğur Keskin, Ulas Fidan, İbrahim Alanbay, Mustafa Ozturk, Ali Ergun Giant Cell Tumor of Distal Radius Treated by En-Bloc Resection and Reconstruction by Non Vascularized Fibular Graft 183 Rajendra G. Malu, Chetan R. Jaju, Vishav Goyal, Santosh Mali, Basavraj Nagoba REVIEW Is PSA Still the Best Marker in Diagnosis and Monitoring of Prostate Cancer? 187 Alpaslan Akbaş, Mohamed Ismat Abdulmajed, Murat Tolga Gülpınar, Eyüp Burak Sancak