bioRxiv preprint doi: https://doi.org/10.1101/708701; this version posted July 19, 2019. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-ND 4.0 International license. In vivo endothelial cell heterogeneity The in vivo endothelial cell translatome is highly heterogeneous across vascular beds Audrey C.A. Cleuren1, Martijn A. van der Ent2, Hui Jiang3, Kristina L. Hunker2, Andrew Yee1*, David R. Siemieniak1,4, Grietje Molema5, William C. Aird6, Santhi K. Ganesh2,7 and David Ginsburg1,2,4,7,8,§ 1Life Sciences Institute, 2Department of Internal Medicine, 3Department of Biostatistics, 4Howard Hughes Medical Institute, University of Michigan, Ann Arbor, Michigan, USA, 5Department of Pathology and Medical Biology, University of Groningen, Groningen, the Netherlands, 6Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA, 7Department of Human Genetics and 8Department of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA * Current address: Department of Pediatrics, Baylor College of Medicine, Houston, TX § Corresponding author; email
[email protected] Running title: in vivo endothelial cell heterogeneity Key words: endothelial cells, RiboTag, gene expression profiling, RNA sequencing Cleuren et al. 1 bioRxiv preprint doi: https://doi.org/10.1101/708701; this version posted July 19, 2019. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-ND 4.0 International license.