Anti-PSMA6 (full length) polyclonal antibody (DPABH-15006) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description The is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

Immunogen Recombinant full length corresponding to Human Proteasome subunit alpha type 6 aa 1- 246.Sequence: MSRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVI VTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAAN WKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQ

Isotype IgG

Source/Host Rabbit

Species Reactivity Mouse, Rat, Human, African green monkey

Purification Immunogen affinity purified

Conjugate Unconjugated

Applications WB, IHC-P

Format Liquid

Size 100 μg

Buffer pH: 7.30; Constituents: 50% Glycerol, 49% PBS

Preservative 0.02% Sodium Azide

Storage Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

GENE INFORMATION

Gene Name PSMA6 proteasome (prosome, macropain) subunit, alpha type, 7 [ Homo sapiens ]

Official Symbol PSMA6

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Synonyms PSMA6; proteasome (prosome, macropain) subunit, alpha type, 6; IOTA; p27K; PROS27; proteasome subunit alpha type-6; PROS-27; macropain iota chain; prosomal P27K protein; proteasome iota chain; macropain subunit iota; 27 kDa prosomal protein; proteasome subunit iota; multicatalytic endopeptidase complex iota chain;

Entrez Gene ID 5687

Protein Refseq NP_001269161.1

UniProt ID P60900

Pathway APC/C-mediated degradation of ; APC/C:Cdc20 mediated degradation of mitotic proteins; AUF1 (hnRNP D0) destabilizes mRNA; Activation of NF-kappaB in B cells

Function NF-kappaB binding; RNA binding; RNA binding; endopeptidase activity

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved