AOCOPM Midyear Educational Meeting March 8-11, 2018

I. Introduction II. Objectives

 Epidemiology of Ocular Injuries

Michael B. Miller, D.O., O.D., M.P.H.  Review of Anatomy Wellstar Occupational Medicine  Examination of eye Atlanta, GA

 Examine eye for trauma and foreign bodies

 Manage chalazia, styes, corneal abrasions, foreign bodies

Ocular Trauma Occupational Ocular Trauma

 “Epidemiological data on eye injuries  In US, 280,000 work-related tx in ED are still rare or totally lacking in large 1999 (Am J Ind Med 2005) parts of the world.” J Clin Ophth Res  2002, BLS est 65,000/year 2016  2009, BLS est. 2.9/10,000 full time  90 % are preventable workers requiring 2 or more days off  Prevalence rates vary a great deal (5-  NIOSH Work-RISQS query shows 15%) 134,000 in 2015  Approx 50% work-related  Non-traumatic ocular illnesses (allergic conjunctivitis) grossly underreported

Occupational Ocular Trauma Risk Factors- Ocular Trauma

 Majority are males  BLS est. 60% fail to wear proper eye  Most are in age 25-44 protection incl. side/top shields  Metalworkers at highest risk  Use of tools (unskilled use increases risk 48X)  Others: agriculture, construction, manufacturing  Performing unusual task (< 1 day/week)  Types of injuries: Abrasions, FB/splash,  Working overtime (3X inc risk) Conjunctivitis, Burns, Contusion,  Distraction, fatigue, Rushed Open/Penetrating wound,  Assoc with sleep duration not stat signif

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PPE Effect- Ocular Trauma Anatomy

 44% reported eye injury despite PPE (Occ Med, Jan 2009)  Reported increase use of PPE during work following eye injury (from median 20% to 100%) (Workplace Health Safety, 2012)  Role of provider education in prevention….Yuge!

Anatomy of the orbital septum Anatomy of the eye and surrounding structures

IV. Elements of Eye Elements of - Examination Office equipment

 Visual Acuity  Penlight  light reflexes and corneal reflexes  Topical anesthetic (tetracaine, ophthaine)  Extraocular muscles/cover test  Dilating drops (Mydriacyl, Cyclogyl)  Eye pads/ paper tape/tincture of  Visual fields- confrontation and Amsler grid benzoin/ointment (Lacrilube or E-mycin)  Red reflex/ophthalmoscopy  Irrigating solution (Dacriose)  Biomicroscopy (slit lamp examination)  Fluorescein strips  Intraocular Pressure (IOP)  Woods light  Sterile swabs  Occluder  Snellen chart/tumbling E chart/Allen cards

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V. Pediatric/Well child eye exam Pediatric eye exam

 Newborn Red Reflex- dark room, use  Infants ( 6 months – 3 years) ophthalmoscope at 1 foot  In addition to above: Pupillary response  Fixation and Following (CN III, IV, VI) Observe for eye deviation  Corneal light reflex (Hirschberg) Observe for congenital cataracts  Cover test

Pediatric eye exam Pediatric eye exam

 Children ( 3 years – 5 years)  Children age 6 years and older  Start to use visual acuity tests- Snellen,  Use Snellen chart for visual acuity Tumbling E

V. Developmental landmarks VI. Frequency of examinations

 Newborn- Unable to fix and follow  High risk infants (premature, maternal before age 3 months factors, child abuse, Systemic disease)  6 months-2 years: Fix and follow a face,  High risk children and young adults toy, or light  African-American over 20 yrs  3 yrs-5 yrs: 20/40 or better  Hx of eye disease/problems  6 yrs: 20/30 or better  Hx of systemic illness  Family hx of eye disease (glaucoma)

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Screening methods for refraction in infants and Frequency of Examinations children

 Age 20 – 39: At least one exam  Age 40-64: Exam every 2-4 years  Age > 65: Exam every 1-2 years

Vision development Ophthalmia neonatorium

Hirschberg Test and Purkinje Images Pseudostrabismus Child with

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Modified fluorescein dye disappearance test VI. Visual Acuity

 Blurred vision is the most common eye chief complaint Snellen fraction: Numerator is testing distance, denominator is distance at which object subtends angle of 5 minutes of arc/or distance at which normal eye can see the object Recorded without (sc) and with (cc) correction at 20 feet (optical infinity) and 16 inches. Right eye, left eye, both eyes (OD, OS, OU)

Visual Acuity Visual acuity

 Recording of results:  Pinhole: If VA is worse than 20/30  20/20  If VA improves, patient has uncorrected  20/60 –2 refractive error otherwise suspect media  10/400 opacity, retinal disorder, or optic nerve  Counting fingers (CF at 5 feet) disease  Hand motion (HM at 5 feet)  Light perception (LP) or No light perception (NLP) with or without projection

Visual Acuity The Snellen optotype

 Macular function can be tested using “auto-ophthalmoscopy” or “entoptic phenomenon”  Intact macula: patient sees images of retinal vessels

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Visual acuity charts Visual acuity charts

Visual acuity charts Visual acuity notations

Notations for recording near visual acuity Titmus and random-dot-E stereoacuity tests

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Titmus and random-dot-E stereoacuity tests VII. Pupillary exam

 Normal round, 3-5 mm  Anisocoria-unequal sized , normal in up to 20%  Semi-dark room, bright light,  Direct and consensual reaction should be equal

Pupillary exam Pupillary Exam

Afferent pupil defect: optic nerve  Efferent defect: Either in Parasym or Sympathetic system Direct light: pupil dilates  CN III defect: no direct response, pupil Consensual and near response: normal dilated, no near response, no consensual  Adie’s Tonic pupil: slow direct, near and consensual response, pupil dilated (decreased peripheral reflexes)  Argyll-Robertson: miotic pupil, no direct or consensual response, normal near response (light-near dissociation)- midbrain lesion seen in sarcoid, multiple slerosis

Pupillary Exam Pupillary exam

 Sympathetic system:  Physiologic anisocoria  Horner’s syndrome: pupil constricted, normal reactions to light, near (ptosis,  Unequal size, normal reaction to light , miosis, anhydrosis) near, consensual

 Amaurotic/blind eye: dilated pupil, no reaction to light, near, consensual

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Pupillary light reflex Evaluating the pupillary light response

Evaluating pupil size Evaluating pupil size

Diagnosing relative afferent pupillary defect in the presence of an efferent pupillary defect Extraocular muscle exam

 EOM actions (LR6 SO4)3  Primary position of gaze  Corneal light reflex- nasal to center of  Cover/Uncover test to test for phoria or tropia  Alternate cover test- can measure amount of deviation  Red lens test/Maddox rod test  Six cardinal positions of gaze- note limitations

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Cover-uncover test Alternate-cover test

Corneal light reflex tests for ocular misalignment The Worth-4-Dot test

Pseudostrabismus Use of glasses to correct accomodative esotropia

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Use of bifocal glasses to correct accommodative Use of glasses to correct accomodative esotropia esotropia

Use of bifocal glasses to correct accommodative esotropia Child with esotropia

VIII. Visual field exam Traquair's island of vision

 Normal visual field: Superior 50, Nasal 60, Inferior 70, Temporal 90  Test each quadrant- count fingers  Simultaneous temporal and nasal fields- checks for extinction phenomenon (count fingers or red bottle tops)  Amsler grid- central 10 degrees- monocular

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Traquair's island of vision Confrontation visual field testing

Amsler grid Tangent screen

Goldmann manual kinetic perimetry Automated static perimetry

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Automated visual field printout IX. Biomicroscopy (Slit lamp)

 General inspection  Cornea  Anterior chamber   Lids/lashes  Lens

Types of biomicroscopic illumination Types of biomicroscopic illumination

Types of biomicroscopic illumination Types of biomicroscopic illumination

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Types of biomicroscopic illumination Types of biomicroscopic illumination

Types of biomicroscopic illumination X. Fundus exam

 Direct ophthalmoscopy  Start with plano (0) power at 10 inches  Note red reflex then add + power to focus on front of eye then add – power to focus from front to back of eye as you get closer to eye with scope  Optic nerve head- note size of disc and central depression (cup) as a ratio called cup to disc ratio (CDR)- normal ratio is .3 or less and bilaterally symmetric  Fovea and light reflex is lateral (temporal) to disc  Note retinal artery and vein size as A/V ratio (normally 2/3 or greater)

Fundus exam Papilledema

 Dilated exam  Tropicamide (Mydriacyl) 1%  Neosynephrine 2.5%

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XI. The Red Eye Evaluation of Red Eye

 Differential Dx  Is vision affected?  Acute conjunctivitis  Check visual acuity!  Foreign body sensation?  Acute iritis  Photophobia?  Acute glaucoma  Trauma?  Corneal trauma/abrasion  Contact lens wearer?  Corneal fluorescein staining?  Discharge?-purulence- bacterial

Red Eye Evaluation Red Eye Evaluation

General observation-penlight exam  Pupil reaction- small if iritis, keratitis, abrasion Topical anesthetic (Tetracaine, Opthaine)?  Pattern of redness- “ciliary flush”- injection at Keratitis-corneal abrasion/contact lens limbus and indicates iritis, angle closure, or overwear, photophobia keratitis Iritis- no fb sensation, photophobic  Corneal opacity/fb? White area= infectious Angle closure glaucoma- general distress, HA, keratitis malaise, nausea, vomiting, dull ache, decreased acuity, mid-dilated pupil, poor  Anterior chamber- hypopyon or hyphema? direct response

Red Eyes Managed by Primary Care Red Eyes- Referral Needed

 Conjunctivitis (bacterial, viral, allergic)  Angle closure glaucoma  Corneal abrasion  Hyphema  Corneal foreign body  Hypopyon  Contact lens overwear  Iritis  Subconjunctival hemmorhage  Keratitis/corneal ulcer  Blepharitis  Stye  Chalazion

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Acute conjunctivitis/bacterial conjunctivitis Bacterial conjunctivitis

 Common  Empirical therapy  Moderate to copius discharge/matting of  Broad spectrum- Polytrim, Ocuflox, lashes Quixin, Sulfacetamide  No effect on vision  Erythromycin ophthalmic oint at night  No pain  If cornea intact- Tobradex, Maxitrol,  Clear cornea Pred-G, Vasocidin  Staph A., H.influenza,Strep pneu,  Use qid to q1h depending on severity Pseudomonas a.  Advise patient very contagious/hygiene

Viral Conjunctivitis Viral Conjunctivitis

 Serous discharge, pre-auric nodes,  No work or school until no discharge injection, lid edema, fever, sore throat  Hygiene (PCF), corneal infiltrates, bilateral  Topical steroids/combination med if (EKC), subconj. hemmorhage cornea intact- Pred Forte/Tobradex bid-  Adenoviruses qid  Tell patients- sx get worse for 7-10 days  Highly contagious before getting better, resolve in 3-6  Usually self-limiting weeks

Chlamydial Conjunctivitis Allergic conjunctivitis

 Consider if chronic red eye no better with  Hx of seasonal allergies/Itching, photophobia, burning and conj other therapy injection  Thin, watery discharge if seasonal  Corneal pannus, corneal infiltrates, follicles,  Ropy, thick discharge with large papillae if vernal conjunctivitis pre-auric node, mucus or stringy discharge  Pre-treatment with Crolom, Alomide, Alocril, Alamast, Optivar, Patanol x 4 weeks with recurrent seasonal allergies Sexually active teens, young adults, neonatal  Tx- mild cases, cold compresses, artificial tears, Lacrilube, OTC Tx- Oral TCN for 3 weeks, Erythromycin for 3 topical decongestants weeks, Doxycycline for 1 week, or  Avoid rubbing eyes!  Moderate to severe- Patanol or Livostin, topical NSAID (Acular, Azithromycin 1 gram- single dose Voltaren) Topical tx- Erythromycin, sulfacetamide tid x 3  Topical steroids (Alrex, Vasocidin, Vexol, Flarex) if very weeks symptomatic  Topical Cyclosporine 2% gtts qid if steroids ineffective  Oral antihistamines

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Giant Papillary Conjunctivitis XII. Corneal/Conjunctival (GPC) Foreign Body

 Associated with soft contact lens wear  Check for corneal perforation/anterior  Fb sensation, itching, excess mucus and chamber large (1 mm) papillae on upper lid conj  Fluorescein- look for aqueous leakage thru  Weeks to years after starting CL wear wound (Seidel’s sign) (mean= 18 months)  Topical anesthetic (ophthaine, tetracine)  Tx= stop CL wear, new lenses, preservative  Evert upper eyelid free solutions  Remove with swab, spud, needle, or burr  Artificial tears, Topical antihistamines under slit lamp (Patanol), topical steroids in severe cases  If fb is in visual axis, advise regarding possible scarring and loss of acuity

XIII. Corneal Abrasion XIV. Chalazion

 Visual acuity, Size, shape, location, depth  Painless nodules in lids  Anterior chamber reaction (may have  Granulomatous inflamm of Meibomian glands secondary iritis)  Topicals won’t help  Topical anesthetic- limit instillation  Hot compresses/massage qid  Woods Lamp or Slit Lamp with fluoroscein  Kenalog 10/ml- use up to 0.3ml from  5%); topical antibiotics, analgesia. Severe palpebral side and 30 gauge needle pain- topical NSAIDs (Acular, Voltaren)  Depigmentation may occur- don’t use if dark  Patching may help pain if abrasion over 50% skin of cornea- not if contact lens wearers  Biopsy if recurrent to r/o sebaceous gland Ca because of risk of infection  If CL wearer-Ciloxan, Ocuflox, Tobrex

XV. Hordeolum (stye) XVI. Preseptal cellulitis

 Painful, swollen lid with pustule (this  Painful, swollen lid, normal vision and differentiates from chalzion) motility; no proptosis  Staph infection of glands  Not systemically ill/may follow sinusitis  Topicals won’t help  Staph, Gr. A Strep, Strep pyogenes  Oral antibiotics (Diclox, E-mycin, TCN,  Limit spread to posterior septum with Amoxil x 10 days) immediate oral antibiotics (Amoxicillin,  I&D if external Augmentin, E-mycin, IV Nafcillin,Oxacillin if severe)  May result in chalazion if chronic

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XVII. Orbital cellulitis XVIII. Blepharitis

 Pain, red, swelling, proptosis, vision loss, loss  Inflamm of lid margins and lashes of motility, systemically ill, fever  Red, collarettes (fibrin around lashes),  Spread from teeth, sinus, lid penetration madarosis (loss of lashes), trichiasis (inturned  Staph, Strep, H. flu lash), plugged glands, conjunctivitis  Potential- intracranial infection, septicemia,  Lid hygiene- tearless shampoo, commercial cavernous sinus thrombosis scrubs (Ocu-clear, Lid Scrub, Lid Wipes)  Immediate hospital/ IV antibiotics  Moderate, severe, chronic- topical or oral (Cefuroxime, Cefoxitin, Ceftriaxone, meds: Sulfacetamide, Tobramycin, E-mycin, Ticar/Clavulanate) Polysporin bid-qid  Excessive inflamm and pain- use combo meds: Tobradex, Maxitrol, Blephamide, Vasocidin

XIX. Dacryocystitis XX. Episcleritis

 Nasal aspect, lower lid  Sectoral injection, cornea clear, mild  Mucopurulent discharge pain  Fever, severe red swelling  Young adults, self-limiting (2-3 days),  Anaerobes:Pepto-streptococcus, Propionibacterium, Fusobacterium most freq usually idiopathic, may be assoed with pathogens RA, SLE, IBD, Gout, Sarcoidosis)  If afebrile- oral antibiotics (Augmentin,  Topical mild steroids (FML, Pred-mild) q Ceclor), topical antibiotics, warm compresses 4 h; cold compresses, artificial tears  If febrile- hospitalized with IV Ancef

XXI. Scleritis XXII. Pinguecula/itis

 Severe, boring pain, photophobia, decreased  Yellow, lipid-like deposits at limbus of vision, tearing exposed conjunctiva  Scleral vessels dilated, deep red in sector or  Degeneration of collagen in conjunctiva diffuse pattern results in dryness, irritation,  Tx- cycloplegia, topical steroid, oral NSAID,  Older population, environmental exposures, oral prednisone Solar/UV light  Consider underlying systemic disorder: RA,  Ocular lubricating drops: Tears Naturale II, SLE, Gout, Syphilis, Zoster, Ankylosing Lacrilube, Refresh PM spondylitis, Wegener’s granulomatosis  Topical steroids: Pred Mild, Vexol, Pred Forte,  Tests: CBC, ESR, RF, ANA, HLA-B27, FTA- Inflamase Forte ABS, CXR, S-I joint films

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XXIII. Pterygium XXIV. Ocular Trauma

 Raised, red, triangular wedge,  Have A,B,Cs been addressed? fibrovascular growth on nasal limbus  What was vision before injury and after injury?  UV light exposure, warm dry climates or  Is there past hx of amblyopia dust/smoke  Did it occur at work?  Topical decongestants (Naphcon-A);  Eye protection and what type? steroids (FML, Vexol, Pred-mild)  Chemical exposure/eye irrigated?  Surgery if in visual axis/ cosmesis  Paresthesias around the eye?  Last oral intake?

Ocular Trauma Ocular Trauma

 Visual acuity is most important element  check with transillumination-tears,  Examine bony structure of orbit for anisocoria, mydriasis displacemnt  Lens instability (phacodonesis) due to rupture  Blowout fx accompanies blunt trauma of zonules  Enophthalmos, restricted motility, lid  Traumatic cataract anesthesia  Traumatic vitreous hemm  Tx broad spectrum antibiotics  Retinal trauma- hemm, fb, choroidal tears,  Thorough check for perf retinal tears, commotio retinae  Hyphema- tx strong cycloplegia and bed rest  Intraocular fb- remove within 12-24 hours x3-5 days. Check IOP.

Ocular trauma-chemical burn Blow Out Fracture Alkali more serious than acid Acids create initial burn then cease, alkali penetrat4cornea to  Signs: edema, ecchymosis of lid destroy stroma, and endothelium  Restriction of motility especially vertical Copious flush with salline  Orbital crepitus (subcut emphysema) Test with litmus paper; If ph 6-8, dc lavage  Hypoesthesia of ipsilateral cheek, entrap of infraorb nerve, Debride necrotic tissue with slit lamp  Risk of medial wall fx is orbital cellulitis Swabs in fornices  CT of orbits- axial and coronal views Cycloplegic and broad spectrum antibiotic  If entrapment, with diplopia, surgery in 10-14 days to allow for resolution of hemm and Pressure patch if large area (50%) edema Add topical 1%prednisolone acetate q 2-4.  Medial wall fx- start Keflex, E-mycin qid x14 Monitor IOP d. Medial wall fx resolves spontaneously in 3-

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Commotio retinae Hordeolum

Adenovirus infection: clinical features, diagnosis, and treatment Subconjunctival hemorrhage

Giant papillary conjunctivitis Scleritis

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Seborrheic blepharitis is probably the most common Episcleritis in rheumatoid arthritis cause of anterior lid margin involvement

Correlation of recurrence with pterygium morphology Asymmetry of the optic cups

Asymmetry of the optic cups Traumatic hyphema

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Cortical cataract Posterior subcapsular cataract

Less severe nonproliferative diabetic retinopathy Preseptal cellulitis

A 14-year-old girl who presented with a red, sensitive Streptococcal bacterial cellulitis secondary to orbital right lower eyelid trauma

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Nasolacrimal sac massage Dacryocystitis

Conjunctivitis Dacryocystitis in a boy aged 16 years

Hemorrhagic conjunctivitis Dacryocystitis in a neonate aged 2 weeks

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Acute conjunctival chemosis An 8-year-old girl with "allergic shiners"

Hypopyon in juvenile rheumatoid arthritis Band keratopathy in juvenile rheumatoid arthritis

Punctate epithelial erosions, punctate epithelial Peripheral thinning of the cornea keratitis, and punctate subepithelial infiltrates

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Herpes infection of the eye Optic nerve drusen

Acute anterior uveitis Anterior segment complications of closed-globe injury

Thelazia gulosa

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XXVI. Skills Stations

 Slit Lamp Evaluation of the Eye  Eyelid eversion using slit lamp  Corneal foreign body removal with slit lamp  Fluorescein staining of the eye/Woods Lamp

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