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Appendix This appendix was part of the submitted manuscript and has been peer reviewed. It is posted as supplied by the authors.

Supplemental material

Mortality at day 28 according to the presence or absence of delirium

Of the 336 patients who had at least one delirium assessment completed on the study day, 68 patients were deemed to have delirium and of these patients 15% (10/68) were deceased at hospital discharge.

For the remaining 268 patients assessed as not delirious, 11% (30/268) were deceased at hospital discharge.

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Case report form questions

1. Was the patients’ delirium status assessed at least once on the study day? If yes, continue to question 2; if no go to question 6.

2. Number of times patient’s delirium status was clearly documented during the study day.

3. Number of times patient was documented with delirium, including hyperactive and hypoactive, during the study day OR patient was not documented as delirious on the study day.

4. For the first delirium status documented on this study day, what was the assessment method used? Options include Confusion Assessment Method for the ICU (CAM-ICU), Intensive Care Delirium Screening Checklist (ICDSC), clinical opinion, other (please specify).

5. For the first delirium status documented on this study day, what type of delirium was documented? Options include hyperactive (i.e. agitated) delirium, hypoactive (i.e. not agitated) delirium, documented with both hyperactive and hypoactive delirium, type of delirium not specified, assessed as not delirious.

6. Was a Richmond Agitation Sedation Scale (RASS) score recorded on the study day? If yes, continue to question 7; if no go to question 8.

7. Highest and lowest RASS score/s recorded on study day.

8. Was another assessment score tool (other than RASS) used to assess the patients’ sedation level on the study day? Options include other sedation score documented (please specify scoring system/tool), no other sedation score documented on the study day.

9. Were any of the following medications administered on the study day (via any route)? Options include clonidine, dexmedetomidine, haloperidol, olanzapine, quetiapine, risperidone.

10. Was the patient physically restrained while in the ICU at any time during the study day?

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Point Prevalence Program Day 11 list of participating sites and investigators

Coordinating centre List of investigators The George Institute for Global Health, Naomi Hammond, Serena Knowles, Annie , NSW Gao, Yang Li, John Myburgh, Ian Seppelt, Sarah Grattan, Conrad Nangla Site List of investigators Angliss Hospital (Eastern Health), Upper Graeme Duke, Andrew Shelton, Nick Ferntree Gully, VIC Kokotsis, Dianne Parker Auckland City Hospital, Cardiothoracic and Shay McGuinness, Rachael Parke, Eileen Vascular Intensive Care Unit, Auckland, New Gilder, Magdalena Butler, Keri-Anne Zealand Cowdrey, Samantha Ryan, Melissa Woollett, Karina Duffy Auckland City Hospital, Department of Colin McArthur, Lynette Newby, Yan Chen, Critical Care Medicine, Auckland, New Rachael McConnochie, Catherine Zealand Simmonds Ballarat Base Hospital, Ballarat, VIC Angus Richardson, Dianne Hill Bankstown-Lidcombe Hospital, NSW Jyotsna Dwivedi, Manoj Saxena, Kathleen Brennan, Sonja Hedges, Mariamma Varghese, Simon Abel Barwon Health, University Hospital Claire Cattigan, Allison Bone, Tania , VIC Elderkin, Tania Salerno Box Hill (Eastern Health), , Vic Stephanie Hunter Caboolture Hospital, Caboolture Hospital, Mahesh Ramanan, Bronwyn Johnson, QLD Rebekah Swift, Joby Mathew, Jince Baby, Angela Gentile, Glipsy James, Courtney Connew, Kylie Annetts Cabrini Hospital, Melbourne, VIC Vineet Sarode, Shannon Simpson Calvary Mater Newcastle, Newcastle, NSW Katrina Ellem, Toni McKenna Hospital, ACT Sumeet Rai, Frank van Haren, Shakira Spiller Christchurch Hospital, Christchurch, New Seton Henderson, Jan Mehrtens Zealand Dandenong Hospital, Dandenong, VIC George Lukas, Kate Shepherd, Nicole Percy Epworth Richmond, Melbourne, VIC Gabrielle Hanlon, Jonathan Barrett, Julie O'Donnell Fiona Stanley Hospital, Murdoch, WA Edward Litton, Annamaria Palermo, Susan Pellicano, Ege Eroglu, Adrian Regli Flinders Medical Centre, , SA Shailesh Bihari, Elisha Matheson, Tapaswi Shrestha, Xia Jin, Russell Laver

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Footscray Hospital (Western Health), Craig French, Samantha Bates, Miriam Melbourne, VIC Towns, Yang Yang Gold Coast University Hospital, QLD James Winearls, Mandy Tallott, Angelly Martinez, Maimoonbe Gough, Priscilla Harvey Ipswich Hospital, Ipswich, QLD Neeraj Bhadange, Kristine Ryan, Shannon Treay Logan Hospital, Logan, QLD Kellie Sosnowski, Lynette Morrison, Joanne Sutton, Melanie Cooper Maroondah Hospital, Ringwood East, VIC Graeme Duke, Deborah Welsh Mater Hospital, , QLD Katherine Jongebloed Isabel, Anne Leditschke Middlemore Hospital, Auckland, New Tony Williams, Rima Song, Vivian Lai, Dinu Zealand Girijadevi North Shore Hospital, Auckland, New Janet Liang, Danielle Hacking Zealand Princess Alexandra Hospital, Brisbane, QLD Jason Meyer, Emma Saylor, Krista Wetzig Redcliffe Hospital, Redcliffe, QLD Alexis Tabah, Maree Duroux Rockingham General Hospital, Cooloongup, Ravikiran Sonawane, Nicholas Ward WA Royal Brisbane and Women's Hospital, Fiona Coyer, Jennifer Palmer Brisbane, QLD Royal Darwin Hospital, Lewis Campbell, Margaret Phillips, Rebecca Garcia Royal North Shore Hospital, Sydney, NSW Elizabeth Yarad, Frances Bass, Naomi Hammond, Julia Piloswky, Angela Ashelford Royal Prince Alfred Hospital, Sydney, NSW Jennifer Coles, David Gattas, Heidi Buhr, David Massey Sir Charles Gairdner Hospital, Nedlands, WA Matthew Anstey, Rashmi Rauyinar, Brad Wibrow, Erina Myers St John of God Hospital Subiaco, WA Edward Litton, Janet Ferrier St John of God Murdoch Hospital, WA Adrian Regli, Annamaria Palermo

St Vincent’s Hospital, Sydney, NSW Hergen Buscher, Claire Reynolds

St Vincent's Hospital Melbourne, John Santamaria, Jennifer Holmes Melbourne, VIC Sunshine Coast University Hospital, QLD Peter Garrett, Lauren Murray, Loretta Forbes, Teena Magurie

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Sunshine Hospital (Western Health), Craig French, Samantha Bates, Miriam Melbourne, VIC Towns, Anna Tippett, Rebecca Morgan Tauranga Hospital, Tauranga, New Zealand Troy Browne, Jennifer Goodson, Jacqui Shippey The Alfred, Melbourne, VIC Andrew Udy, Meredith Young, Jasmin Board, Phoebe McCracken, Emma Martin, Shirley Vallance The Royal Melbourne Hospital, Melbourne, Adam Deane, Deborah Barge, Kathleen VIC Byrne, Sarah Doherty Hospital, Toowoomba, QLD Adam Visser, Judith Smith Waikato Hospital, Hamilton, New Zealand Robert Martynoga, Sarah Rogers, Amelia Butler, Kara Trask Wellington Hospital, Wellington, New Paul Young, Anna Hunt, Cassie Lawrence, Zealand Deborah Hendry

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