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ANTICANCER RESEARCH International Journal of Cancer Research and Treatment

ISSN: 0250-7005

Volume 35, Number 2, February 2015

Contents

Reviews

Curcumin and Cancer Stem Cells: Curcumin Ηas Asymmetrical Effects on Cancer and Normal Stem Cells. P.P. SORDILLO, L. HELSON (Quakertown, PA, USA) ...... 599

Mechanisms and Clinical Significance of Histone Deacetylase Inhibitors: Epigenetic Glioblastoma Therapy. P. LEE, B. MURPHY, R. MILLER, V. MENON, N.L. BANIK, P. GIGLIO, S.M. LINDHORST, A.K. VARMA, W.A. VANDERGRIFT III, S.J. PATEL, A. DAS (Charleston, SC; Columbus, OH, USA) . 615 Targeting the Peritoneum with Novel Drug Delivery Systems in Peritoneal Carcinomatosis: A Review of the Literature. T.R. VAN OUDHEUSDEN, H. GRULL, P.Y.W. DANKER, I.H.J.T. DE HINGH (Eindhoven, the ) ...... 627 Mode of Action of Anticancer Peptides (ACPs) from Amphibian Origin. C. OELKRUG, M. HARTKE, A. SCHUBERT (Leipzig, ) ...... 635 Potential Anticancer Properties and Mechanisms of Action of Curcumin. N.G. VALLIANOU, A. EVANGELOPOULOS, N. SCHIZAS, C. KAZAZIS (, ; Leicester, UK) ...... 645 Experimental Studies

In Vitro Evaluation of 3-Arylcoumarin Derivatives in A549 Cell Line. M.A. MUSA, M.Y. JOSEPH, L.M. LATINWO, V. BADISA, J.S. COOPERWOOD (Tallahassee, FL, USA) ...... 653 Contents continued on the back cover ISSN (print): 0250-7005 ISSN (online): 1791-7530 Editorial Board Editorial Office: International Institute of Anticancer Research, 1st km Kapandritiou-Kalamou Rd., Kapandriti, P.O. Box 22, Attiki 19014, P.A. ABRAHAMSSON, Malmö, G. R. F. KRUEGER, Köln, Germany Greece. Tel / Fax: +30-22950-53389. B. B. AGGARWAL, Houston, TX, USA D. W. KUFE, Boston, MA, USA T. AKIMOTO, Kashiwa, Chiba, Japan Pat M. KUMAR, Manchester, UK E-mails: Editorial Office: [email protected] A. ARGIRIS, San Antonio, TX, USA Shant KUMAR, Manchester, UK Managing Editor: [email protected] J. P. ARMAND, Toulouse, O. D. LAERUM, , ANTICANCER RESEARCH supports: (a) the establishment and the V. I. AVRAMIS, , CA, USA F. J. LEJEUNE, , activities of the INTERNATIONAL INSTITUTE OF ANTICANCER R. C. BAST, Houston, TX, USA L. F. LIU, Piscataway, NJ, USA RESEARCH (IIAR; Kapandriti, Attiki, Greece); and (b) the organization of the International Conferences of Anticancer Research. D.-T. BAU, Taiwan, ROC D. M. LOPEZ, Miami, FL, USA G. BAUER, Freiburg, Germany E. LUNDGREN, Umea°, Sweden For more information about ANTICANCER RESEARCH, IIAR and the E. E. BAULIEU, Le Kremlin-Bicetre, France H. T. LYNCH, Omaha, NE, USA Conferences, please visit the IIAR website: www.iiar-anticancer.org Y. BECKER, Jerusalem, Israel Y. MAEHARA, Fukuoka, Japan Publication Data: ANTICANCER RESEARCH (AR) is published monthly E. J. BENZ, Jr., Boston, MA, USA J. MAHER, , UK from January 2009. Each annual volume comprises 12 issues. Annual J. BERGH, , Sweden J. MARESCAUX, Strasbourg, France Author and Subject Indices are included in the last issue of each volume. D. D. BIGNER, Durham, NC, USA J. MARK, Skövde, Sweden ANTICANCER RESEARCH Vol. 24 (2004) and onwards appears online with Stanford University HighWire Press from April 2009. A. 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