Antibody Avidity in Humoral Immune Responses in Bangladeshi Children and Adults Following Administration of an Oral Killed Cholera Vaccine
Antibody Avidity in Humoral Immune Responses in Bangladeshi Children and Adults following Administration of an Oral Killed Cholera Vaccine The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters Citation Alam, Mohammad Murshid, Daniel T. Leung, Marjahan Akhtar, Mohammad Nazim, Sarmin Akter, Taher Uddin, Farhana Khanam, et al. 2013. “Antibody Avidity in Humoral Immune Responses in Bangladeshi Children and Adults Following Administration of an Oral Killed Cholera Vaccine.” Clinical and Vaccine Immunology 20 (10): 1541–48. https://doi.org/10.1128/CVI.00341-13. Citable link http://nrs.harvard.edu/urn-3:HUL.InstRepos:41542638 Terms of Use This article was downloaded from Harvard University’s DASH repository, and is made available under the terms and conditions applicable to Other Posted Material, as set forth at http:// nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of- use#LAA Antibody Avidity in Humoral Immune Responses in Bangladeshi Children and Adults following Administration of an Oral Killed Cholera Vaccine Mohammad Murshid Alam,a Daniel T. Leung,a,b,c Marjahan Akhtar,a Mohammad Nazim,a Sarmin Akter,a Taher Uddin,a Farhana Khanam,a Deena Al Mahbuba,a Shaikh Meshbahuddin Ahmad,a Taufiqur Rahman Bhuiyan,a Stephen B. Calderwood,b,c,d Edward T. Ryan,b,c,e Firdausi Qadria Centre for Vaccine Sciences, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesha; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USAb; Departments of Medicinec and Microbiology and Immunobiology,d Harvard Medical School, Boston, Massachusetts, USA; e Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts, USA Downloaded from Antibody avidity for antigens following disease or vaccination increases with affinity maturation and somatic hypermutation.
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