Authors: Pallavi Subhraveti Ron Caspi Peter Midford Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_000702945Cyc: Clostridium sp. KNHs205 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari queuosine queuosine ammonium ammonium phosphate phosphate

RS0126315 RS0105905 Amt Amt PstB PstB

queuosine queuosine ammonium ammonium phosphate phosphate

Polyprenyl Biosynthesis Degradation Macromolecule Modification tRNA-uridine 2-thiolation Aldehyde Degradation an inactive a [DNA]-3'- a 5'-phospho- a nascent a peptidoglycan a [bis(guanylyl a []- an [amino-group and selenation (bacteria) a reduced + serotonin formate phosphoenol formate degradation II ribonucleoside NAD peptidoglycan dimer (generic) molybdopterin) MEP a tRNA Asx asp carrier protein]- di-trans,poly-cis L-rhamnose degradation I SAM dGTP hydroxyl [DNA] cys L-glutamine CTP dGDP pyruvate UTP ATP roseoflavin Amine and Polyamine Biosynthesis D-galactose degradation I (Leloir pathway) trehalose degradation II (cytosolic) methylglyoxal triphosphate flavodoxin (meso-DAP CTP C-terminal-γ- Aminoacyl-tRNA Charging -undecaprenyl 5'-phosphate L-asparagine biosynthesis gln cys degradation I glutaminyl-tRNA phosphate biosynthesis a glycogen reductase containing) endolytic chaperone]- (L-glutamate 5- III (tRNA-dependent) spermidine biosynthesis III β-D-galactopyranose α-L-rhamnopyranose α α DNA transglutaminase anaerobic anaerobic N-acetyl- biosynthesis via transamidation spermidine biosynthesis I (2E,6E)-farnesyl , -trehalose transglycosylase L-cysteine 2-C-methyl-D- aspartate-- semialdehyde-2- IPP cysteine desulfurase: glycogen/starch/ methylglyoxal domain-containing ribonucleoside- ribonucleoside- bifunctional yl)-L-glutamategamma- diphosphate galactose L-rhamnose anaerobic deoxyguanosinetriphosphate endolytic MltG: mltG erythritol 4-phosphate pyruvate tRNA(Asn) asp BR73_RS0117630 alpha-glucan lactoylglutathione D: ligD protein: triphosphate triphosphate riboflavin kinase/ glutamyl- glu mutarotase: mutarotase: trehalase / alfa- ribonucleoside- triphosphohydrolase: transglycosylase cytidylyltransferase: kinase: pyk ligase: aspS SAM arg [+ 4 isozymes] : : NAD- lytic cysteine BR73_RS0122605 reductase: nrdD reductase: nrdD FAD synthetase: phosphate SAM isoprenyl an [L-cysteine BR73_RS0107930 rhaM L-rhamnosidase triphosphate BR73_RS0118905 MltG: mltG BR73_RS0125660 aspartate-- aspartate-- glgP BR73_RS0123140 dependent transglycosylase desulfurase [+ 4 isozymes] ribonucleoside ribonucleoside BR73_RS0117825 an [amino-groupreductase: : desulfurase]-S- / mannosyl (R)-S- reductase [+ 2 isozymes] 2-C-methyl-D- tRNA(Asn) tRNA(Asn) adenosylmethionine α-D-galactopyranose β-L-rhamnopyranose DNA ligase lytic domain-containing NifS: nifS triphosphate triphosphate carrier protein]-argC adenosylmethionine BR73_RS0118875 sulfanyl-L-cysteine glycogen/ oligosaccharide lactoylglutathione activating protein: transglycosylase protein: erythritol 4-phosphate pyruvate ligase: aspS C-terminal-γ- ligase: aspS gln decarboxylase: speD LigA: ligA [+ 4 isozymes] a [protein] N 6 - reductase: reductase: decarboxylase: speD starch/alpha- L-rhamnose glucosidase: BR73_RS0101620 domain-containing BR73_RS27200 cytidylyltransferase: dGTP roseoflavin (5-phospho- aspartate-- an L-glutamyl- di-trans,octa-cis glucan family galactokinase: [(5-hydroxy-1H- BR73_RS0123355 BR73_RS0123355 adenine dAdoMet agmatine : BR73_RS0113065 triphosphate protein: a [bis(guanylyl ispD L-glutamyl)- tRNA(Asn) [tRNA Gln ] imidazole BR73_RS0113870 anaerobic 2'-deoxyguanosine indol-3-yl)ethyl]- putrescine dAdoMet -undecaprenyl phosphorylase: BR73_RS0114375 BR73_RS27200 dinucleotide an L-aspartyl- L-glutamate gln glycerol a [TusA sulfur- ribonucleoside- [DNA] NMN GlcNAc-1,6- ala molybdopterin) Asx ligase: aspS diphosphate glgP a lipid II L-glutamine [tRNA ] Asp-tRNA(Asn) phosphate carrier protein]-S- α-D-galactose α β (R)-lactate AMP cofactor 4-(cytidine 5'- dCTP dUTP an L-aspartyl- polyamine undecaprenyl- UDP-α-D- keto-L-rhamnulose -D-glucopyranose -D-glucopyranose triphosphate anhydro-MurNAc- /Glu-tRNA(Gln) synthase: polyamine sulfanyl-L-cysteine α 1-phosphate chaperone]-S- diphospho) Asn imidazole aminopropyltransferase: diphosphate an -limit dextrin reductase a mature a nascent pentapeptide [tRNA ] amidotransferase: sulfanyl-L-cysteine -2-C-methyl- glycerol hisF hisH aminopropyltransferase: phosphatase: activating peptidoglycan peptidoglycan gatB gatA gatC speE 4-alpha- D-erythritol Asp-tRNA(Asn) phosphate [+ 8 isozymes] speE BR73_RS0120085 protein: nrdG with (L-alanyl- (meso-DAP a 5-phosphooxy- glucanotransferase: /Glu-tRNA(Gln) 1 di-trans,octa-cis γ synthase: L-glutamyl- N -(3-aminopropyl) a [TusD sulfur- pyruvate -D-glutamyl- containing) with amidotransferase: ammonium -undecaprenyl malQ L-rhamnulofuranose D-glucopyranose hisF hisH Gln agmatine spermidine carrier protein]-S- an active meso-2,6- GlcNAc terminus gatB gatA gatC [tRNA ] a debranched [+ 8 isozymes] phosphate sulfanyl-L-cysteine rhamnulokinase: 5'-deoxyadenosine a flavodoxin met ribonucleoside diaminopimeloyl- a 4-phosphooxy- α-limit dextrin ROK family semiquinone Asp-tRNA(Asn) BR73_RS0118700 glucokinase: triphosphate D-alanine) L-aspartyl- ammonium tetrapeptide Asn /Glu-tRNA(Gln) rhamnulokinase: reductase [tRNA ] glycogen/starch/ BR73_RS0125585 Amine and Polyamine Degradation amidotransferase: spermidine a [TusE sulfur alpha-glucan rhaB D-glucopyranose gatB gatA gatC Asp-tRNA(Asn) 34 carrier protein]-S L-rhamnulose a [ribosomal 3-benzyl-3,6 - an N-terminal- 2 an N-terminal- (3R,5S)-3- a uridine in tRNA phosphorylase: 6-phosphate 3-aci- an N-formyl-L- a [protein]- a ribonucleoside N - phosphoenol an L-cysteinyl- /Glu-tRNA(Gln) -sulfanylcysteine D-glucopyranose 1-phosphate superpathway of N-acetylglucosamine, a sulfurated protein S12] D-cellobiose bis(cysteinylglycine) FAD L-methionyl-L- L-methionyl- hydroxy-1- glgP nitropropanoate methionylaminoacyl- L-threonine formate succinylglutamate pyruvate Pro N-acetylmannosamine and N- [sulfur carrier] 89 triphosphate dADP GTP [tRNA ] amidotransferase: an L-glutaminyl- glycogen/ L-aspartate tRNA - 6-(hydroxymethyl) threonyl-[protein] glycyl-[protein] pyrroline-5- gatB gatA gatC Gln tRNA 2- acetylneuraminate degradation ribonucleoside- [tRNA ] starch/alpha- rhamnulose- cellobiose -diketopiperazine carboxylatepyrroline-5- thiouridine(34) 1-phosphate N-acetylneuraminate nitronate FAD:protein FMN succinylglutamate triphosphate glucan family UDP-glucose-- UDP-glucose fucose degradation MiaB/RimO family peptide phosphorylase: ribonucleoside methionyl methionyl Cys- carboxylate synthase aldolase: rhaD monooxygenase: transferase: desuccinylase: reductase, an L-asparaginyl- phosphorylase: hexose-1-phosphate 4-epimerase radical SAM deformylase: BR73_RS0123410 membrane triphosphate aminopeptidase: pyruvate aminopeptidase: tRNA(Pro) reductase: Asn MnmA: mnmA ROK family BR73_RS0125905 BR73_RS0103795 BR73_RS0123165 adenosylcobalamin- [tRNA ] glgP GalE: galE β N-acetyl-D- methylthiotransferase: def dipeptidase: reductase: BR73_RS0123765 kinase: pyk BR73_RS0123765 deacylase: proC glucokinase: uridylyltransferase: -L-fucopyranose nitronate cellobiose FAD:protein FMN succinylglutamate dependent: nrdJ galT [+ 2 isozymes] DHAP (S)-lactaldehyde mannosamine BR73_RS0117615 peptide BR73_RS0122340 BR73_RS0123355 [+ 2 isozymes] [+ 2 isozymes] ybaK pyrroline-5- a 2-thiouridine 34 BR73_RS0125585 monooxygenase: phosphorylase: transferase: desuccinylase: α-D- α-D-glucopyranose anaerobic [+ 2 isozymes] carboxylate tRNA charging in tRNA UDP-α-D-galactose N-acetylmannosamine 30S ribosomal BR73_RS0103335 deformylase: BR73_RS0107170 BR73_RS0109815 BR73_RS0123170 glucopyranose 1-phosphate ribonucleoside- dGTP reductase: kinase: protein S12 def 3-benzyl-3,6 - an N-terminal L- pyruvate an N-terminal tRNA uridine-5- 1-phosphate dATP Pro proC α BR73_RS0114050 methylthiotransferase α bis(cysteinyl)- 6- gly triphosphate met met cys a tRNA Ile Met Met Arg Tyr glu Phe -L-fucopyranose [unspecified -D- threonyl-[protein] glycyl-[protein] ile a tRNA elongator tRNA met initiator tRNA met arg a tRNA tyr a tRNA glu a tRNA phe a tRNA carboxymethylaminomethyl(34) phospho- N-acetyl-D- D-glucopyranose (hydroxymethyl) a [protein]-FMN- reductase: nrdD Hyp RimO: rimO 3-oxopropanoate nitrite degradation glucopyranose succinate synthesis MnmG: mnmG phospho- sugar mutase: fucose isomerase: mannosamine formate a L-methionylaminoacyl- -diketopiperazine AMP L-threonine glu sugar mutase: BR73_RS0100145 D-arabinose degradation I products] 1-phosphate val a tRNA Val gln a tRNA Gln tRNA asp asp leu a tRNA Leu a tRNA Ala ala gly a tRNA Gly lys a tRNA Lys tRNA uridine-5- L-arabinose BR73_RS0118695 6-phosphate tRNA a 2'- BR73_RS0100145 a [ribosomal Asn isoleucine-- methionine- methionine- His arginine- tyrosine-- Trp Cys glutamate-- Thr phenylalanine- carboxymethylaminomethyl(34) phospho- degradation I N-acetylmannosamine- asn tRNA his a tRNA trp a tRNA cys a tRNA thr a tRNA [+ 3 isozymes] 5'-deoxyadenosine met protein S12]-3- an unsulfurated deoxyribonucleoside tRNA ligase: Pro -tRNA -tRNA ser -tRNA tRNA ligase: tRNA ligase: -tRNA ligase: synthesis GTPase MnmE: mnmE phospho- sugar mutase: D-arabinopyranose 6-phosphate pro a tRNA ser a tRNA methylsulfanyl- [sulfur carrier] 5'-triphosphate BR73_RS0101405 ligase: metG ligase: metG valine--tRNA ligase: glutamine--tRNA aspartate- ligase: argS BR73_RS0115185 leucine--tRNA ligase: alanine--tRNA ligase: BR73_RS0124995 glycine--tRNA ligase: lysine--tRNA pheS pheT a 5-carboxymethylaminomethyl- sugar mutase: BR73_RS0124635 L-arabinopyranose L-fuculose 2-epimerase: L-fucose isomerase: L-arabinose L-aspartate 89 asparagine- isoleucine-- methionine-- methionine-- BR73_RS0102905 ligase/YqeY domain -tRNA histidine- arginine- tyrosine-- BR73_RS0115240 BR73_RS0117160 tryptophan- cysteine-- glutamate-- BR73_RS0125100 threonine- ligase: lysS phenylalanine-- 2-thiouridine 34 in tRNA BR73_RS0124635 D-glucopyranose BR73_RS0113775 BR73_RS0118705 isomerase: L-fuculokinase: N-acetyl-D- -tRNA tRNA ligase: proline--tRNA ligase: tRNA ligase: tRNA ligase: valine--tRNA ligase: fusion protein: ligase: aspS --tRNA -tRNA -tRNA tRNA ligase: leucine--tRNA ligase: alanine--tRNA -tRNA tRNA ligase: tRNA ligase: glycine--tRNA ligase: -tRNA lysine--tRNA tRNA ligase: pheS 6-phosphate araA BR73_RS0118700 β ligase: asnS BR73_RS0115665 BR73_RS0101530 BR73_RS0104655 BR73_RS0104655 BR73_RS0106425 BR73_RS0105805 [+ 2 isozymes] ligase: serS ligase: hisS ligase: argS BR73_RS0119210 BR73_RS0118675 ligase: alaS ligase: trpS BR73_RS0124290 BR73_RS0125165 BR73_RS0125985 ligase: thrS ligase: lysS BR73_RS0107680 D-ribulose glucosamine 7,8-dihydrofolate a pentaglycine (5Z,8Z,11Z,14Z,17Z) luteolin 7-O-[ -D- N,N'- an N-terminal- an N-terminal- L-ribulose 34 + a protein with L-fuculose 6-phosphate a 5,10-gly a uridine NADPH H cross-bridge of glucosyluronate-(1,2)-β- 2-oxoglutarate isochorismate diacetylchitobiose H O a tRNA glu (S)-4-amino-5- L-methionyl-L- L-methionyl-L- ser sec a protein monoglutamate -icosapentaenoyl-CoA 2 GTP ATP a tRNA H + RS0112255 H + a 5-aminomethyl-2- 1-phosphate N-acetylglucosamine- methylenetetrahydrofolate in tRNA peptidoglycan NPXTN motif oxopentanoate an L-asparaginyl- an L-methionyl- an L-methionyl- an L-glutaminyl- an L-tryptophanyl- an L-phenylalanyl- D-ribulokinase: ribulokinase: D-glucosiduronate]-4'- alanyl-[protein] seryl-[protein] ATP- an L-isoleucyl-[tRNA Ile ] an L-prolyl-[tRNA Pro ] an L-valyl-[tRNA Val ] an L-aspartyl-[tRNA asp ] an L-seryl-[tRNA ser ] an L-histidyl-[tRNA His ] an L-arginyl-[tRNA Arg ] an L-tyrosyl-[tRNA Tyr ] an L-leucyl-[tRNA Leu ] an L-alanyl-[tRNA Ala ] an L-cysteinyl-[tRNA Cys ] an L-glutamyl-[tRNA Glu ] a glycyl-[tRNA Gly ] an L-threonyl-[tRNA Thr ] an L-lysyl-[tRNA Lys ] thiouridine 34 in tRNA D-glucopyranose BR73_RS0118700 6-phosphate O-β-D-glucosiduronate ribonucleoside- [tRNA Asn ] [elongator tRNA Met ] [initiator tRNA Met ] [tRNA Gln ] [tRNA Trp ] [tRNA Phe ] araB N,N'- dependent 6-phosphate gellan degradation deacetylase: nagA dihydrofolate acyl-CoA 2-succinyl-5- triphosphate D-ribulose tRNA uridine-5- class B diacetylchitobiose glutamyl- methionyl methionyl serine- Clp protease L-ribulose 5- D-glucosamine reductase: thioesterase: enolpyruvyl- elongation reductase, a reduced 1-phosphate phosphate carboxymethylaminomethyl(34) BR73_RS0100450 sortase: BR73_RS0103710 beta-glucuronidase: phosphorylase: factor 4: lepA tRNA aminopeptidase: aminopeptidase: -tRNA ATP-binding H O c-type gellan 6-hydroxy-3- adenosylcobalamin- 2 6-phosphate synthesis enzyme MnmG: mnmG srtB BR73_RS0108255 BR73_RS0106250 reductase: BR73_RS0123765 BR73_RS0123765 ligase: subunit a 5-methylaminomethyl- L-ribulose-5- DHAP (S)-lactaldehyde dihydrofolate acyl-CoA cyclohexene-1- [+ 8 isozymes] dependent: nrdJ RS0123175 cytochromean oxidized 34 tRNA uridine-5- beta-glucuronidase: hemA [+ 2 isozymes] [+ 2 isozymes] serS ClpX: clpX 2-thiouridine in tRNA phosphate 4- reductase: thioesterase: carboxylic-acid N,N'- [+ 2 isozymes] O c-type Nucleoside and Nucleotide Biosynthesis D-xylose a protein with a peptide with 2 carboxymethylaminomethyl(34) BR73_RS0108310 diacetylchitobiose + [+ 2 isozymes] epimerase: BR73_RS0123305 BR73_RS0105115 synthase: menD H 2+ 2+cytochrome degradation I α NPXT carboxyl an N-terminal phosphate dATP Cd CadA Cd unsaturated gellan glycolaldehyde araD -D-glucosamine synthesis GTPase MnmE: mnmE phosphorylase: GDP an L-glutamyl- an N-terminal L- an N-terminal a peptide DHAP end attached to L-asparagine an L-seryl- UMP biosynthesis III 6-phosphate β BR73_RS0112870 Glu met met L-seryl-[protein] sec superpathway of guanosine pyrimidine deoxyribonucleotides a 5-methylaminomethyl- D-xylose tetrasaccharide D-xylulose β β-D-glucuronate luteolin 7-O- - 2-succinyl-5-enolpyruvoyl- [tRNA ] alanyl-[protein] [tRNA ] superpathway of adenosine 5-aminoimidazole ribonucleotide biosynthesis I inosine-5'-phosphate biosynthesis II (1,4)- -D-xylan D-arabinose degradation II 5,6,7,8- + a pentaglycine (5Z,8Z,11Z,14Z,17Z) nucleotides de novo biosynthesis II 2-(S-geranyl) xylose 5-phosphate glucosamine- a 5-carboxymethylaminomethyluridine 34 NADP coenzyme A D-diglucuronide 6-hydroxy-3-cyclohexene- nucleotides de novo biosynthesis II de novo biosynthesis I degradation a 7,8-dihydrofolate tetrahydrofolate cross-bridge of -icosapentaenoate 2+ 2+ 34 isomerase: glycosyl 6-phosphate in tRNA 1-carboxylate N-acetyl-D- N-acetyl-α-D- Cd CadA Cd gln Cell Structure Biosynthesis thiouridine in tRNA peptidoglycan hydrogencarbonate UDP CTP PRPP AIR xylA family 88: β D-arabinopyranose deaminase: glucosamine glucosamine glycolate a (1->4)- -D-xylan IMP IMP ribonucleotide- 5-(carboxyamino)imidazole D-xylulose BR73_RS0100325 endo-1,4-beta- L-fucose isomerase: nagB 1-phosphate asp diphosphate amidophosphoribosyltransferase: carbamoyl- ribonucleotide mutase: purE peptidoglycan biosynthesis I (meso-diaminopimelate containing) [+ 2 isozymes] xylanase: BR73_RS0118705 glucosamine- IMP reductase: CDP BR73_RS0106265 a 5-methylaminomethyl- xylulokinase: chitobiose D-ribulose CAIR BR73_RS0107305 6-phosphate 34 a [protein]-L- β phosphate BR73_RS0124580 α 2-(Se-phospho) 4-deoxy-L- β-D-Glcp-(1->4) degradation a 5,10- a 2-thiouridine sn-glycerol a CDP- a long-chain a D-aspartyl- a peptide with methyl -D-glucoside a (1->4)- dehydrogenase: ribonucleoside- 5-phospho-β- UDP-N-acetyl- -D-glucosamine xylB coenzyme A an apo [peptidyl- coenzyme A an apo-[aryl- coenzyme A [EntB aryl- H O a RNA-DNA hybrid 5 34 synthase: carB adenylosuccinate gly 34 [+ 3 isozymes] deaminase: a type IV prepilin 2 glutamate-O an N-terminal a cytidine lys α-D-glucan BR73_RS0124585 selenouridine in tRNA threo-hex-4- -α-L-Rhap- a (1->4)-β-D-xylan ribulokinase: methylenetetrahydrofolate in tRNA 3-phosphate diacylglycerol fatty acyl-CoA [tRNA asp ] 6-phosphate guaB synthase: triphosphate D-ribosylamine phosphoribosylaminoimidazolesuccinocarboxamide D-xylulose N,N'-diacetylchitobiose nagB carrier protein] carrier protein] carrier protein] -methyl-ester in tRNA Ile2 1,4-alpha- BR73_RS0123250 dUDP UDP-N-acetylglucosamine enopyranuronate (1->3)-D-Glcp trehalose degradation VI (periplasmic) oligosaccharide araB L-methionine BR73_RS0106315 reductase, synthase: BR73_RS0106260 1-carboxyvinyltransferase: 5-phosphate 6'-phosphate glucan XMP adenosylcobalamin- phosphoribosylamine- xylan 1,4-beta- D-ribulose F6P tRNA uridine-5- acyl-CoA ribonuclease 6-phospho- branching carbamoyl BR73_RS0101580 α,α-trehalose CDP-diacylglycerol-- holo-[acyl- holo-[acyl- holo-[acyl- D-tyrosyl-tRNA(Tyr) chemotaxis-specific tRNA asp dependent: nrdJ -glycine ligase: purD SAICAR a 5-methylaminomethyl- xylosidase: 5-phosphate carboxymethylaminomethyl(34) prepilin thioesterase: HI: rnhA methionyl beta- phosphate [+ 2 isozymes] N-monoacetylchitobiose glycerol-3-phosphate 3- carrier- carrier- carrier- deacylase: protein-glutamate lysidine(34) protein adenylo-succinate 2-selenouridine 34 BR73_RS0107510 synthesis enzyme MnmG: mnmG peptidase: BR73_RS0105115 aminopeptidase: glucosidase: glutamine- dUTP ribonucleotide- UDP-N-acetyl-α-D- 6'-phosphate phosphatidyltransferase: protein] protein] protein] ribonuclease HII: BR73_RS0103695 methyltransferase synthetase GlgB: glgB adenylosuccinate lyase: in tRNA melibiose degradation trehalase / alfa-L- BR73_RS27035 BR73_RS0123765 ascB a (1,6)-α-D- hydrolyzing GMP adenylosuccinate diphosphate GAR glucosamine-enolpyruvate 6-phospho- β-D-xylopyranose tRNA uridine-5- pgsA synthase: synthase: synthase: acyl-CoA BR73_RS0116265 CheB: cheB TilS: tilS aspartate synthase: guaA deoxyuridine BR73_RS0106270 rhamnosidase / mannosyl carboxymethylaminomethyl(34) prepilin peptidase: thioesterase: [+ 2 isozymes] glucosyl-(1,4) lyase: reductase: UDP-N- beta- acpS acpS acpS α carbamoyltransferase 5'-triphosphate phosphoribosylglycinamide melibiose oligosaccharide synthesis GTPase MnmE: mnmE BR73_RS0108805 BR73_RS0103710 β-D-glucose - -glucan BR73_RS0106270 BR73_RS0124580 AICAR glucosidase: 1-(3-sn- asp regulatory subunit: nucleotidohydrolase: acetylmuramate glu glucosidase: CMP DNA a nucleoside 5'- tRNA D-aspartate a [protein]-α- MeOH a lysidine 34 GMP BR73_RS0124585 formyltransferase: ascB phosphatidyl) MeOH 6-phosphate BR73_RS0116615 BR73_RS0106300 BR73_RS0107715 dehydrogenase: murB queuosine biosynthesis BR73_RS0113065 3',5'-ADP a holo [peptidyl- 3',5'-ADP a holo-[aryl- 3',5'-ADP a holo-[EntB aryl- monophosphate L-glutamate met a peptide in tRNA Ile2 bifunctional ala alpha-galactosidase: N-acetyl-D-glucosamine a 5-aminomethyl-2- -sn-glycerol a cleaved type a long-chain aspartate AMP nucleoside triphosphate dCDP α : III (queuosine salvage) a 7,8-dihydrofolate carrier protein] carrier protein] carrier protein] a peptide phosphoribosylaminoimidazolecarboxamide UDP-N-acetyl- -D-muramate BR73_RS0123160 6-phosphate 34 3-phosphate IV prepilin carbamoyltransferase: guanylate kinase: FGAR BR73_RS0101435 thiouridine in tRNA fatty acid pyrophosphohydrolase: formyltransferase/IMP cyclohydrolase: purH [+ 5 isozymes] galactose mutarotase: pyrB BR73_RS0101770 queuosine adenylate kinase: mazG UDP-N- BR73_RS0107930 cellulose and hemicellulose degradation (cellulolosome) phosphoribosylformylglycinamidine FAICAR racemase: α β BR73_RS0126375 superpathway of pyrimidine deoxyribonucleoside salvage acetylmuramate--L- -D-glucopyranose -D-glucopyranose UDP-N-acetyl-α-D-muramoyl- Glc Man an apo-[LYS2 L- N-acetyl-β-D- an N-terminal- an apo-[FeFe] an unstable dUMP dCTP synthase: BR73_RS0121310 D-galactopyranose D-glucopyranose 3 9 (+)-7-epi- a D-tyrosyl- an L-asparaginyl- D-sedoheptulose GDP alanine ligase: murC BR73_RS0106280 di-trans,octa-cis- γ GlcNAc -[protein] coenzyme A 2-aminoadipyl- coenzyme A AsbD acyl- coenzyme A [EntF L-seryl- H O aci-nitroethane glucosaminyl-(1 L-methionyl-L- hydrogenase RecA filament- N-carbamoyl- bifunctional β L-alanyl- -D-glutamyl-L- 2 jasmonoyl-CoA 2 Tyr Asn 1,7-bisphosphate thymidylate 2'-deoxycytidine queuine a (1->4)- -D-xylan a feruloyl- a xyloglucan undecaprenyl phosphate carrier protein carrier protein] [tRNA ] [tRNA ] L-aspartate FGAM phosphoribosylaminoimidazolecarboxamide lysyl-D-alanyl-D-alanine carrier-protein] -> 4)-N-acetyl- valyl-[protein] subunit [FeFe] DNA complexDNA ADP synthase: thyA UDP-N-acetyl-α-D- D-glt β formyltransferase/IMP cyclohydrolase: purH endo-1,4-beta- trehalase / alfa- -D-muramate hydrogenase repair dihydroorotase: nucleoside muramoyl-L-alanine acyl-CoA nitronate class II ribonucleotide- ribonucleotide- ATP dTMP phosphoribosylformylglycinamidine D-mannose xylanase: phospho-N- L-rhamnosidase holo-[acyl- holo-[acyl- holo-[acyl- D-tyrosyl-tRNA(Tyr) aminoacyl-tRNA methionyl H-cluster protein BR73_RS0120975 ribonucleotide- ribonucleotide- deaminase: cyclo-ligase: BR73_RS0107710 fructose degradation BR73_RS0107305 carrier- carrier- carrier- thioesterase: monooxygenase: fructose-1,6- diphosphate diphosphate IMP UDP-N- degradation a xyloglucan acetylmuramoyl- / mannosyl deacylase: hydrolase: beta- aminopeptidase: bisphosphate maturation RecO: diphosphate diphosphate dTMP kinase: tmk BR73_RS0119280 dCMP protein] protein] protein] BR73_RS0103710 BR73_RS0125905 (S)-dihydroorotate reductase: reductase: acetylmuramoyl-L- preQ β-D-fructofuranose [+ 3 isozymes] ferulate a polysaccharide cellotetraose pentapeptide- oligosaccharide BR73_RS0103695 BR73_RS0100930 hexosaminidase: BR73_RS0123765 aldolase: fba GTPase a stabilizedrecO reductase: reductase: [+ 2 isozymes] AIR 1 D-mannopyranose β synthase: synthase: synthase: acyl-CoA nitronate BR73_RS0124580 BR73_RS0124580 anaerobic (d)CMP kinase: guanine and guanosine salvage alanine--D-glutamate a (1->4)- -D-xylan transferase: glucosidase: BR73_RS0111405 [+ 2 isozymes] HydF: hydF RecA filament- GTP BR73_RS0124580 BR73_RS0124580 dTDP 6-phosphate 1-phosphate1-phosphofructokinase: acpS acpS acpS thioesterase: monooxygenase: BR73_RS0124585 BR73_RS0124585 ribonucleoside- BR73_RS0116425 ligase: murD tRNA mannose-6- oligosaccharide BR73_RS0118320 BR73_RS0113065 DNA complex dihydroorotate BR73_RS0124585 BR73_RS0124585 2'-deoxyuridine pfkB BR73_RS0105115 BR73_RS0103335 D-erythrose an active [FeFe][+ 2 isozymes] triphosphate adenine salvage guanosine(34) phosphate a tRNA Tyr tRNA Asn dehydrogenase dCDP D-tyrosine asn N-acetyl-D- an N-terminal DHAP hydrogenase reductase: nrdD guanosine meso-diaminopimelate UDP-N-acetyl-α-D-muramoyl- transglycosylase isomerase, 1-phosphofructokinase: undecaprenyl-diphospho-N- a holo-[LYS2 L- a holo-[EntF GlcNAc 4-phosphate electron UMP Glc Man 3',5'-ADP 3',5'-ADP a holo-[AsbD acyl- 3',5'-ADP muramate met L-valyl-[protein] subunit anaerobic dADP dTTP thymidine kinase: L-alanyl-D-glutamate Tgt: tgt class I: manA pfkB C1 Compound Utilization and Assimilation γ β-D-glucopyranose 2 9 2-aminoadipyl- L-seryl-carrier transfer subunit: dGDP ribonucleoside pyrimidine/purine β-D-fructose 1,6- acetylmuramoyl-L-alanyl- -D- GlcNAc -[protein] carrier protein] (+)-7-epi- acetaldehyde nitrite ribonucleoside- BR73_RS0117330 nucleoside phosphorylase: D-ala a 7-aminomethyl-7- F6P glutamyl-L-lysyl- D-alanyl-D-alanine 2 carrier-protein] protein] jasmonate BR73_RS0120920 triphosphate adenine 34 bisphosphate triphosphate thymidine BR73_RS0118425 UDP-N- deazaguanosine formate assimilation into 5,10- dihydroorotate reductase: nrdD reductase: dUMP dCTP in tRNA formaldehyde [+ 2 isozymes] D-alanine--D- acetylmuramoyl-L- methylenetetrahydrofolate BR73_RS0123355 oxidation II UDP-N-acetyl-α-D- 2-phospho-4-(cytidine 5'- RNase III mRNA γ β 1939 dehydrogenase: ribonucleoside guanine alanine ligase: alanyl-D-glutamate-- tRNA preQ1(34) S- di-trans,octa-cis- S-methyl-L- a [protein]- dihomo - D-firefly luteolin 7-O- - a uracil a [protein]-L- guanine and guanosine salvage II thymidine kinase: adenine deaminase: ade adenine vancomycin resistance II (glutathione-dependent) γ L-homocysteine diphospho)-2-C-methyl-D-erythritol processing a [protein]-L-lysine H O H O a glycyl-[tRNA Ala ] NADH BR73_RS0120915 triphosphate thymidylate 2, 6-diaminopimelate adenosylmethionine formate muramoyl-L-alanyl- -D- L-glutamine linolenoyl-CoA 2 luciferyl-CoA 2 D-glucuronide in 23S rRNA met methionine superpathway of pyrimidine BR73_RS0117330 phosphoribosyltransferase: BR73_RS0101440 undecaprenyl phosphate methionine ATP PRPP reductase: synthase: ligase: ribosyltransferase- formate-- formaldehyde glutamyl-L-lysyl-D-alanine 23S rRNA biotin bifunctional peptide- orotate nucleobases salvage BR73_RS0107855 xanthine D-alanine--D- Alcohol Degradation BR73_RS0123355 dATP thyA BR73_RS0118420 isomerase QueA: queA tetrahydrofolate 2-C-methyl-D- (uracil(1939)-C(5)) glutamate N- methionine guanosine phosphoribosyltransferase: alanine ligase: ser transglutaminase acyl-CoA acyl-CoA beta-glucuronidase: -methyltransferase NAD(+) (S)-S-oxide uracil 34 phospho-N- bifunctional homocysteine D-tyrosyl-tRNA(Tyr) orotate hypoxanthine BR73_RS0114815 BR73_RS0104510 an epoxyqueuosine ligase: erythritol 2,4- ribonuclease III: domain-containing thioesterase: thioesterase: BR73_RS0108255 acetyltransferase/ diphosphatase: uracil UDP-N-acetyl-α-D-muramoyl- glycerol and glycerophosphodiester degradation S-(hydroxymethyl) acetylmuramoyl- S-methyltransferase/ deacylase: RlmD: rlmD biotin--[acetyl-CoA- reductase phosphoribosyltransferase: adenine and serine racemase VanT D-alanyl-D-alanine in tRNA glycerol degradation V glycerol degradation II 10 BR73_RS0116675 cyclodiphosphate BR73_RS0124285 amino-acid nudC phosphoribosyltransferase: hypoxanthine γ ethanol an N - protein: BR73_RS0103710 BR73_RS0103710 beta-glucuronidase: carboxylase] ligase: MsrA: msrA xanthine AMP D-alanyl-D-alanine L-alanyl- -D-glutamyl- glutathione pentapeptide- methylenetetrahydrofolate synthase: ribonuclease III: BR73_RS0103695 a 5- [+ 2 isozymes] acetyltransferase a protein-L- pyrE dGTP BR73_RS0107935 adenosine salvage I dTMP phosphoribosyltransferase: hpt catalytic subunit: vanT epoxyqueuosine degradation I formyltetrahydrofolate BR73_RS0122605 acyl-CoA acyl-CoA BR73_RS0108310 BR73_RS0104700 phosphoribosyltransferase: meso-2,6-diaminopimelate glycerol glutathione- transferase: reductase: BR73_RS0122430 BR73_RS0124305 1939 ArgJ: argJ guanine amino acid racemase: reductase: glycerol glycerol BR73_RS0116395 [+ 4 isozymes] thioesterase: thioesterase: methyluracil reduced β- methionine- UMP dTMP BR73_RS0114815 bifunctional dependent BR73_RS0118320 N-acetyl-L- orotidine 5'- GMP BR73_RS0106280 BR73_RS0119255 ethanol glycerol glycerol BR73_RS0105115 BR73_RS0105115 in 23S rRNA nicotinamide D- (S)-S-oxide UDP-N- methylenetetrahydrofolate Ala methionine AMP UMP kinase: adenosine kinase: tmk hypoxanthine formaldehyde RNase III a tRNA gly β-D-glucuronate biotinyl-5'- phosphate xanthine acetylmuramoyl- [+ 3 isozymes] bifunctional dehydrogenase: dehydrogenase: dehydrogenase/ 2-C-methyl-D-erythritol- CMP a protein with an luteolin ribonucleotide BR73_RS0118885 pyrimidine/purine xanthine and phosphoribosyltransferase: hpt D-serine D-ala dehydrogenase: undecaprenyl-diphospho-N UMP met an mRNA fragment processing adenylate phosphoribosyltransferase: dTDP a queuosine 34 acetaldehyde- BR73_RS0103905 BR73_RS0103905 methenyltetrahydrofolate N 6 -(γ-glutamyl)- orotidine-5'- nucleoside phosphorylase: pyrimidine ribonucleosides salvage I tripeptide--D-alanyl- BR73_RS0102855 -acetylmuramoyl-L-alanyl-γ- 2,4-cyclodiphosphate di-homo-γ- UDP BR73_RS0114815 xanthosine salvage in tRNA glycerol CoA/alcohol dihydroxyacetone dihydroxyacetone cyclohydrolase FolD: folD mRNA L-lysine crosslink D-firefly luciferin phosphate CMP BR73_RS0118425 D- alanine ligase: D-glutamyl-L-lysyl- D-alanine linolenate hypoxanthine IMP a glycerophosphodiester dehydrogenase: decarboxylase: phosphorylation [+ 2 isozymes] cytidine BR73_RS0118415 D-alanine--D-serine a 5,10- S-formylglutathione phosphoribosyltransferase: hpt glycerol kinase adhE pyrF adenine dTTP xanthosine ligase VanG: vanG methenyltetrahydrofolate CMP UDP-N-acetyl-α-D-muramoyl-L- GlpK: glpK glycerophosphodiester acetaldehyde a [ThiI sulfur- a 2'- DNA with adenine:7,8- D-sedoheptulose a protein-L- UTP pyrimidine/purine uridine kinase: nucleoside di-trans,octa-cis- bifunctional hydrogen selenide a uracil in tRNA H O 5'-deoxyadenosine A ammonium H O Co 2+ sirohydrochlorin DHAP an L-cysteinyl- (R)-lactate (d)CMP kinase: γ O-acetyl-L-serine carrier protein]- diphosphate 2 deoxyribonucleoside dihydro-8- 2 methionine- UMP adenine GMP BR73_RS0112650 deaminase: alanyl- -D-glutamyl-meso-2,6- lipoprotein posttranslational glycerol kinase phosphodiesterase: bifunctional DHAP DHAP ATP [DNA] [tRNA Cys ] 1-phosphate BR73_RS0116425 CTP synthase: nucleoside phosphorylase: undecaprenyl phosphate D-alanyl-D-serine methylenetetrahydrofolate S-sulfanyl- a tRNA precursor 5'-triphosphate oxoguanine mismatch NAD(P)H- D-2-hydroxyacid (R)-S-oxide phosphoribosyltransferase: BR73_RS0119280 diaminopimeloyl-D-alanyl-D-alanine modification GlpK: glpK BR73_RS0105105 acetaldehyde- CTP peptide- CDP BR73_RS0125605 BR73_RS0118425 dehydrogenase/ formate L-cysteine dependent glycerol- dehydrogenase: BR73_RS0107855 CMP [+ 2 isozymes] a [prolipoprotein]- CoA/alcohol methenyltetrahydrofolate 5'-methylthioadenosine/ hydroxylamine sirohydrochlorin class II methionine CTP [+ 2 isozymes] phospho-N- O-acetylhomoserine inorganic group II A/G-specific 3-phosphate aminoacyl-tRNA BR73_RS0119905 xanthine L-cysteine dehydrogenase: cyclohydrolase FolD: folD tRNA 4- adenosylhomocysteine reductase: hcp cobaltochelatase: fructose-1,6- (R)-S-oxide acetylmuramoyl- sn-glycerol 3-phosphate aminocarboxypropyltransferase/ pyrophosphatase: CCA tRNA intron reverse adenine dehydrogenase: hydrolase: D-2-hydroxyacid AMP uridine prolipoprotein adhE Carboxylate Degradation thiouridine(8) nucleosidase: hydroxylamine BR73_RS0105455 bisphosphate reductase xanthine pentapeptide- a 5,10- cysteine synthase: BR73_RS0115650 nucleotidyltransferase: transcriptase/ glycosylase: BR73_RS0113255 BR73_RS0100930 dehydrogenase: CTP Secondary Metabolite Biosynthesis diacylglyceryl synthase BR73_RS0102420 reductase: hcp aldolase: fba MsrB: msrB phosphoribosyltransferase: uridine kinase: transferase: methylenetetrahydrofolate BR73_RS0124330 [+ 2 isozymes] BR73_RS0101485 maturase: ltrA mutY sn-glycerol BR73_RS0125275 a [protein]-L- transferase: lgt acetyl-CoA ThiI: thiI BR73_RS0114815 BR73_RS0112650 BR73_RS0118320 pyruvate fermentation to acetate IV [+ 3 isozymes] [+ 20 isozymes] cobalt- 3-phosphate pyruvate methionine autoinducer AI-2 biosynthesis I prolipoprotein sirohydrochlorin UMP a [ThiI sulfur- a tRNA 5-deoxy-D- cys a tRNA Cys DHAP D-erythrose undecaprenyldiphospho- DHAP a 4-thiouracil + an apurinic site hydroxylamine XMP diacylglyceryl pyruvate phosphate H containing a adenine N-acetylmuramoyl-L-alanyl- transferase: acetate carrier protein]- in tRNA adenine within DNA SAM L-selenocysteine 3' CCA end [DNA] Carbohydrate Biosynthesis γ-D-glutamyl-meso-2,6- BR73_RS0115735 L-cysteine diaminopimeloyl-D-alanyl-D-alanine a [prolipoprotein]- Inorganic Nutrient Metabolism formate C- UDP-N-acetyl-D- undecaprenyldiphospho- S-1,2-diacyl-sn- acetyltransferase: glycogen biosynthesis I (from ADP-D-Glucose) dTDP-β-L-rhamnose UDP-α-D-galactofuranose N 6 -(3-methylbut- sn-glycero-3- an N-acetyl-β- a (1->4)- glucosamine biosynthesis I SAH glyceryl-L-cysteine selenate reduction pflB an [HPr]- phosphoenol (1S,2R)-1- α 3'-dephospho- a double muramoylpentapeptide beta-N- urea cycle an L-rhamnoside a nucleoside a reduced acetylxylan chitin IPP α biosynthesis biosynthesis dissimilatory sulfate sulfite oxidation III sulfite oxidation II a sulfurated [sulfur carrier] 2-en-1-yl)- L-histidine pyruvate ser C-(indol-3- phospho-N- ATP CoA RNA superoxide D-hexosaminide stranded DNA -D-glucan D-glucopyranose acetylglucosaminyltransferase: 37 triphosphate rubredoxin D-glucopyranose 6-phosphate signal peptidase II: reduction I (to adenosine in tRNA yl)glycerol (arachidonoyl) DNA: 4-hydroxy- 1,4-alpha- α-D-glucopyranose α BR73_RS0102410 5'-methylthioadenosine/ 6-phosphate UDP- -D-glucose selenate hydrogen sufide)) acetyl-CoA formate 3-phosphate ethanolamine BR73_RS0125765 glucan glucose-6-phosphate 1-phosphate lipid II (meso adenosylhomocysteine BR73_RS0101175 arg sulfite sulfite alpha-L- beta- acetylxylan beta- 3-methylbut- phospho- dTDP-glucose UDP-glucose 4- sulfate phosphoenolpyruvate- BR73_RS0125770 branching isomerase: diaminopimelate containing) nucleosidase: [+ 2 isozymes] sulfate adenylyl-sulfate adenylyl-sulfate tRNA (N6-isopentenyl rhamnosidase: DNA-directed hexosaminidase: esterase: hexosaminidase: 2-enyl sugar mutase: pyrophosphorylase: epimerase GalE: galE adenylyltransferase phosphate -protein tryptophan dephospho- desulfoferrodoxin: protein BR73_RS0102435 BR73_RS0102420 sulfate reductase reductase adenosine(37)-C2)- BR73_RS0122355 glycerophosphodiester RNA polymerase BR73_RS0111405 DNA: BR73_RS0111880 BR73_RS0111405 diphosphate F6P BR73_RS0100145 BR73_RS0123540 [+ 2 isozymes] an (S-diacyl- subunit CysD: cysD acetyltransferase: pta phosphotransferase: ptsP synthase: trpB CoA kinase: BR73_RS0106790 GlgB: glgB α a lipoprotein adenosine 5'- adenylyltransferase argininosuccinate subunit alpha: subunit alpha: methylthiotransferase phosphodiesterase: subunit delta: gyrB gyrA reductase: UDP- -D-galactose sn-glyceryl) [+ 3 isozymes] BR73_RS0114775 BR73_RS0118005 a negatively a GlgE-glycogen phospho- glucose-1-phosphate S-ribosyl-L-homocysteine signal peptide phosphoselenate subunit CysD: cysD lyase: argH BR73_RS0115580 BR73_RS0115580 MiaB: miaB β-L- a non BR73_RS0105105 BR73_RS0115315 an N-acetyl-β- N-acetyl-D- (E)-4-hydroxy-3-ispH glutamine-- UDP-galactopyranose -L-cysteinyl- ammonium acetyl phosphate supercoiled DNA xylan chitin sugar mutase: thymidylyltransferase APS APS APS rhamnopyranose rhamnosylated [+ 3 isozymes] an alcohol D-hexosamine acetate glucosamine methylbut-2-en- fructose-6- mutase: glf [apolipoprotein] an [HPr protein]- D-glyceraldehyde an oxidized BR73_RS0124635 RfbA: rfbA S-ribosylhomocysteine 6 N -(3-methylbut-2-en- π pyruvate 3-phosphate trp rhamnosyl + 1-yl diphosphate phosphate α dTDP-α-D-glucose adenylyl-sulfate carbamoyl- sulfate acetate kinase: an unsulfurated N -phospho- anandamide sn-glycerol coenzyme A H rubredoxin -D-glucopyranose UDP-Galf lyase: BR73_RS0119920 L-arginino- 5'-deoxyadenosine 1-yl)-2-(methylsulfanyl) met acceptor ADP transaminase reductase L-ornithine phosphate adenylyltransferase BR73_RS0119025 [sulfur carrier] L-histidine 3-phosphate RNA 1-phosphate dTDP-glucose 4,6- selenite succinate polyphosphate adenosine 37 in tRNA (isomerizing) AI-2 a peptide subunit alpha: synthase: carB subunit CysD: cysD : glmS glucose-1-phosphate dehydratase: rfbB an N-acyl-(S- BR73_RS0123250 metabolism acetate diacyl-sn-glyceryl) BR73_RS0115580 sulfate D-glucosamine adenylyltransferase dTDP-glucose 4,6- sulfate -L-cysteinyl- carbamoyl long chain a mature peptidoglycan (meso 4-deoxy-β-D-gluc-4- a 1-acyl-2- 1402 N-acetyl-D- a glucosylated subunit GlgD: glgD dehydratase: rfbB sulfite ornithine an (R)-2- 37 a cytidine a supercoiled UTP 6-phosphate phosphate polyphosphate DMAPP an adenosine galactosamine carbonic acid DMAPP glucose-1-phosphate dTDP-4-dehydro-6- [lipoprotein] argininosuccinate carbamoyltransferase: -diaminopimelate containing) ATP enuronosyl-(1,3)-N- halocarboxylate arachidonoyl- in 16S rRNA duplex DNA gln glycogenin phosphoglucosamine PRPP biosynthesis selenodiglutathione in tRNA 16S rRNA 6-phosphate ribonucleoside- 1,4-alpha- adenylyltransferase: deoxy-α-D-glucopyranose (2R,4S)-2-methyl-2,4- anaerobic sulfite synthase: argF ammonium hydrogencarbonate acetyl-D-galactosamine sn-glycerol UvrD-helicase 4-hydroxy- mutase: reductase: BR73_RS0120140 3-phosphate CTP (cytosine(1402)-N(4) domain-containing triphosphate amino acid glucan BR73_RS0100960 dTDP-4- D-ribose 5- dihydroxydihydrofuran-3-one endolytic transglycosylase 3-methylbut- BR73_RS0104540 L-citrulline polyphosphate HAD family )-methyltransferase carbonic anhydrase: reductase, racemase: branching dehydrorhamnose asrB asrA nitrogen fixation MltG: mltG glycosyl hydrolase tRNA (adenosine(37)-N6) N-acetylglucosamine- protein: 2-enyl α α α phosphate kinase 1: ppk1 hydrolase: adenosylcobalamin- BR73_RS0106280 protein -D-glucosamine a (1->4)- -D-glucan ADP- -D-glucose ribose-phosphate tRNA processing I (ferredoxin) carbamate kinase: family 88: -dimethylallyltransferase phosphatidate RsmH: rsmH 6-phosphate BR73_RS0112465 BR73_RS0122215 diphosphate 3,5-epimerase: rfbC a [DsrC]-trisulfide lytic transglycosylase BR73_RS0119915 dependent: nrdJ GlgB: glgB 1-phosphate pyrophosphokinase: prs sulfide oxidation II BR73_RS0119375 BR73_RS0100325 MiaA: miaA cytidylyltransferase: 16S rRNA deacetylase: nagA [+ 4 isozymes] reductase: glycogen dTDP-4- (2R,4S)-2-methyl-2,3,3,4- glutathioselenol domain-containing [+ 5 isozymes] a single [+ 2 isozymes] D-glutamine [+ 2 isozymes] a polycistronic (flavocytochrome c) N [+ 2 isozymes] BR73_RS0118870 (cytosine(1402)-N(4) ispH a dehydrorhamnose tetrahydroxytetrahydrofuran 2 protein: BR73_RS27200 stranded DNA (E)-4-hydroxy-3- PRPP tRNA precursor nitrogenase long chain N 6 -(3-methylbut- )-methyltransferase CO H O dUTP GlgA: glgA 3,5-epimerase: rfbC polyphosphate D-galactosamine 2 2 methylbut-2-en- α hydrogen sulfide iron protein: nifH carbamoyl an (S)-2- 2-en-1-yl)- 4 RsmH: rsmH acetate N-acetyl- -D- dTDP-4-dehydro- a mature peptidoglycan with (L- a mature peptidoglycan strand 4-deoxy-L-threo-hex- N-acetyl-D- a halide anion a CDP-1-acyl- an N - 6-phosphate 1-yl diphosphate a (1->4)-α-D-glucan phosphate hydroxycarboxylate adenosine 37 glucosamine β-L-rhamnose hydrogen sulfide flavocytochrome c: [+ 2 isozymes] alanyl-γ-D-glutamyl-meso-2,6- (non-reducing terminus) 4-enopyranuronate galactosamine 2-arachidonoyl- methylcytidine 1402 Cofactor, Carrier, and Vitamin Biosynthesis hydrogen selenide ammonium in tRNA 1-phosphate 1,4-alpha-glucan dTDP-4- BR73_RS0109830 diaminopimeloyl-D-alanine) tetrapeptide glycerol in 16S rRNA UDP-N- branching S 0 dehydrorhamnose nickel cofactor a tRNA precursor a tRNA precursor Fatty Acid and Lipid Degradation acetylglucosamine protein GlgB: glgB [2Fe-2S] iron-sulfur flavin biosynthesis I (bacteria and plants) FeMo cofactor biosynthesis 4-aminobenzoate with a 5' with a 5' reductase: rfbD dipyrromethane adenosylcobalamin tetrahydrofolate biosynthesis 5-methylbenzimidazolyl an N-terminal- 2251 pyrophosphorylase: biosynthesis biosynthesis an (S)-2- guanosine an L-aspartyl- CTP a supercoiled α cluster biosynthesis cofactor biosynthesis salvage from cobalamin adenosylcobamide biosynthesis extension and extension and a cob(II)alamin pyruvate DL-allothreonine an alkylated DNA L-methionyl-L- asp O-ureido-L- -amylose a glycogen dTDP-β-L-rhamnose oleate β-oxidation halocarboxylate in 23S rRNA Asn L-ornithine duplex DNA BR73_RS0122770 nicotinate adenine a [4Fe-4S] iron- (7,8-dihydropterin- from adenosylcobinamide-GDP a long 3' trailer short 3' extension fatty acid β-oxidation III ATP ATP [tRNA ] ribonucleoside- 1,4-alpha- an apo-[hydroxymethylbilane 4'-phosphopantetheine cysteinyl-[protein] homoserine 23S rRNA Asp-tRNA(Asn) ATP- UDP-N-acetyl- dinucleotide L-cysteine desulfurase GTP sulfur cluster cob(I)alamin chorismate 6-yl)methyl 4-aminobenzoate ribonuclease (unsaturated, odd number) triphosphate amino acid glucan α synthase]-L-cysteine 5-methylbenzimidazole (guanosine(2251) /Glu-tRNA(Gln) dependent -D-glucosamine aminodeoxychorismate/ diphosphate P protein oleate pyruvate, HAD family DNA-3- reductase, racemase: branching a (3Z)-alk-3- serine argininosuccinate -2'-O)- amidotransferase: DNA pyridin-1-ium- cysteine desulfurase: bifunctional anthranilate synthase component: cob(I)yrinic acid phosphate dikinase: hydrolase: methyladenine methionyl adenosylcobalamin- BR73_RS0106280 protein dihydropteroate enoyl-CoA hydroxymethyltransferase: pantetheine-phosphate synthase: methyltransferase gatB gatA gatC helicase 3,5-dicarboxylate BR73_RS0117630 3,4-dihydroxy- a [hydroxymethylbilane component II: a tRNA rnpA enoyl-CoA a,c-diamide BR73_RS0125095 BR73_RS0119915 glycosylase: aminopeptidase: dependent: nrdJ GlgB: glgB cob(II)alamin BR73_RS0114750 synthase: 5-methylbenzimidazole BR73_RS0122805 adenylyltransferase: BR73_RS0123765 BR73_RS0120140 RlmB: rlmB an L-asparaginyl- D-ornithine RecG: recG mononucleotide synthase] ES intermediate a NifB protein precursor with a tRNA precursor Secondary Metabolite Degradation hydratase/ adenosyltransferase: BR73_RS0122535 2-O- Asn [+ 4 isozymes] 2-butanone- 2 4-amino-4- [+ 5 isozymes] coaD [tRNA ] [+ 2 isozymes] amylopectin ATP- BR73_RS0122420 ribotide phosphate with a short [+ 2 isozymes] methylguanosine 2251 [+ 3 isozymes] 4-phosphate hydroxymethylbilane with a K-cluster cob(I)yrinic acid deoxychorismate a 5' extension isomerase: BR73_RS0105545 phosphoenol dCTP a single an S-sulfanyl-[L- oleoyl-CoA + dependent synthase/GTP a,c-diamide adenosylcobinamide- 3' extension β BR73_RS0110455 diphosphate H a DNA containing in 23S rRNA cysteine desulfurase] synthase: hemC 7,8- superpathway of -D- a (2E)-2- AMP pyruvate acetaldehyde an (S)-2- an alkylated canavaninosuccinate stranded DNA sacrificial cyclohydrolase II: adenosyltransferase: GDP ribonuclease D-galacturonate degradation I fructoselysine and adenosylcobalamin gly a halide anion an apurinic/ a [hydroxymethylbilane dihydropteroate glucuronosides degradation enoyl-CoA hydroxycarboxylate 3'-dephospho-CoA nucleobase an N-terminal L- Fatty Acid and Lipid Biosynthesis sulfur BR73_RS0105545 ribazoletransferase: P protein psicoselysine degradation triphosphate met BR73_RS0111895 synthase] ES intermediate aldehydo-D- apyrimidinic site cysteinyl-[protein] transferase 2,5-diamino-6- 3 cob(II)alamin- BR73_RS0105510 component: a β-D-glucuronoside a NifB protein 4-aminobenzoate 6 LarE: larE (5-phospho-D- hydroxymethylbilane [corrinoid Coα-[α-(5- rnpA galacturonate N -(D-psicosyl) (2E,9Z)- palmitate biosynthesis (type II fatty acid synthase) an S-sulfanyl-[cysteine with an L-cluster CDP-diacylglycerol acyl-CoA hydrolysis 5-carboxy-1-(5- ribosylamino) synthase: hemC adenosyltranferase] methylbenzimidazolyl)]- beta-glucuronidase: glucuronate -L-lysine octadecenoyl-CoA desulfurase]-[disordered- 7,8-dihydrofolate di-trans,octa-cis an [amino-group carrier 37 a (1->4)- biosynthesis I O-phospho-β- Coβ-adenosylcobamide BR73_RS0108255 isomerase: quinoxaline-2- (S)-5-amino-3- adenine pyrimidin- nitrogenase an uncharged UDP-α-D-glucose acetyl-CoA propanoyl-CoA H O a D-aminoacyl- a peptide with a an N-modified a holo [PedN acyl- γ acetyl-CoA α a 2,3,4-saturated form scaffold a [hydroxymethylbilane monoglutamate aryl-carrier protein carboxyl adenylate -undecaprenyl oxohexanoate 2 protein]-C-terminal- - in tRNA val leu -D-glucan an acetoacetyl-[acp] D-ribofuranosyl) 4(3H)-one iron- 5'-phosphate beta-glucuronidase: uxaC [tRNA] leader sequence aminoacyl-[tRNA] carrier protein] 1 hypoxanthine DHAP fatty acyl CoA protein] complex synthase] ES intermediate tRNA phosphate ACP S- (L-glutamyl)-L-glutamate tRNA1(Val) acetyl-CoA 1,4-alpha- acyl-CoA pyridin-1-ium-3- bifunctional 4 molybdenum BR73_RS0108310 amino acid glucan 3-oxoacyl-[acyl- NAD(P)H- carbonyl adenylate hydroxymethylbilane cob(I)alamin- D-tagaturonate N 6 -(D-fructosyl) (S)-3-hydroxy-(9Z) malonyltransferase: acetylglutamate (adenine(37)-N6)- xanthine carboxylase thioesterase: ATP- diaminohydroxyphosphoribosylaminopyrimidine cofactor 2-oxoglutarate [corrinoid D-glucopyranuronate 3-keto-5- acyl-CoA thioesterase: methyltransferase: racemase: biotin carboxyl branching carrier-protein] dependent glycerol- synthase: hemC α α -L-lysine -octadecenoyl-CoA acyl carrier protein: undecaprenyl- D-tyrosyl-tRNA(Tyr) signal aminoacyl-tRNA fabD kinase: argB dehydrogenase: BR73_RS0105115 dependent deaminase/5-amino-6-(5-phosphoribosylamino) biosynthesis adenosyltranferase] Co -[ -(5- tagaturonate aminohexanoate BR73_RS0105115 BR73_RS0101750 BR73_RS0106280 carrier protein reductase: fabG 3-phosphate a [cysteine desulfurase]- homocitrate a 7,8-dihydrofolate BR73_RS0121905 phosphate glucose deacylase: peptidase I: lepB hydrolase: ACP S- an [amino-group carrier an N 6 - BR73_RS0104415 acyl-CoA sacrificial uracil reductase RibD: ribD a holo-[hydroxymethylbilane protein cob(I)yrinic acid methylbenzimidazolyl)]- reductase: fructoselysine cleavage protein: acyl-CoA thioesterase: protein: accB GlgB: glgB dehydrogenase: S-sulfanyl-[disordered- synthase: 5-oxo-L-proline metabolism phosphotransferase: BR73_RS0103695 BR73_RS0100930 37 [+ 3 isozymes] a (3R)-3- 5-amino-6-(5- synthase] NifE: nifE Coβ-adenosylcobamide BR73_RS0116510 6-kinase: [+ 3 isozymes] BR73_RS0113080 BR73_RS0103710 [+ 3 isozymes] malonyltransferase: protein]-C-terminal- methyladenine D-leucine BR73_RS0113255 thioesterase: sulfur a,c-diamide dihydrofolate val xanthine starch form scaffold phospho-D- a NifEN protein BR73_RS0113705 BR73_RS0110670 BR73_RS0105740 fabD γ-(5-phospho-L- in tRNA [+ 5 isozymes] hydroxybutanoyl-[acp] sn-glycerol BR73_RS0103710 transferase adenosyltransferase: reductase: a [protein] with a [protein] with 3-oxo-(9Z)- a malonyl[PedN 1 a 2,3,4-saturated protein] complex D-ribulose ribosylamino)uracil aldehydo-D-glucuronate D-altronate N 6 -(6-phospho- glutamyl)-L-glutamate malonyl-CoA 3-phosphate LarE: larE complex containing (2R)-homocitrate BR73_RS0105545 an N-terminal an N-terminal a quinoxaline-2- an uncharged an uncharged acyl-carrier 3-hydroxyacyl- a [LarE]-S-[5-carboxy- cysteine desulfurase: bifunctional BR73_RS0123305 octadecenoyl-CoA α (S)-3- an N-modified fatty acid 5-phosphate an L-cluster adenosylcob(III) altronate D-fructosyl) carboxyl-[aryl- -D-glucopyranosyl- UMP acetoacetate propanoate a D-amino acid a leader sequence a peptide protein] ACP dehydratase glycerol-3- 1-(5-O-phosphono- BR73_RS0117630 diaminohydroxyphosphoribosylaminopyrimidine dihydrofolate L-glutamine L-glutamate glucuronate AMP aminobutanoyl-CoA tRNA amino acid tRNA bifunctional alamin-[corrinoid dehydratase: -L-lysine carrier protein] diphosphoundecaprenol FabZ: fabZ phosphate 1-O- β-D-ribofuranosyl) [+ 4 isozymes] deaminase/5-amino-6-(5-phosphoribosylamino) reductase: 4-amino-2-methyl-5- isomerase: an S-sulfanyl-[cysteine 3,4-dihydroxy- adenosyltranferase] BR73_RS0116500 acyltransferase pyridin-1-ium-3- uracil reductase RibD: ribD BR73_RS0100450 diphosphomethylpyrimidine uxaC a (2E)-but-2-enoyl-[acp] PlsY: plsY carbonyl]-L-cysteine desulfurase]-S- 2-butanone- 5-amino-6-(5- cob(I)yrinic acid biosynthesis I 2-dehydro-3- (7Z)-hexadecenoyl-CoA acyl-[acyl- sulfanyl-[disordered- 4-phosphate a NifEN protein a,c-diamide a tetrahydrofolate a [protein] with D-fructuronate a [protein]-S- a uridine 34 a mismatched a double-stranded 1498 5-dehydro- a 1-acyl-sn ATP- phospho-D- deoxy-D-gluconate β O-acetyl-L- an acyl-[acyl- an (S)-2- an (R)-2- a holo [PedD acyl- a uracil an L-glutamyl- sn-glycerol 5-deoxy-D-ribose carrier protein] complex containing AIR -D-glucose methanethiol carbamoyl L-ornithine 4-deoxy-D- -glycerol 3- dependent form scaffold synthase/GTP ribitylamino)uracil adenosyltransferase: an N-terminal 5- 2-dehydro-3- homoserine carrier protein] sulfanyl-L-cysteine in tRNA halocarboxylate halocarboxylate DNA carrier protein] oligonucleotide in 16S rRNA [tRNA Gln ] 1-phosphate thioesterase pathway an M-cluster phosphomethylpyrimidine 6-phosphate lys phosphate DNA mismatch bifunctional 16S rRNA glucuronate S-methyl-5- phosphate sacrificial protein] complex cyclohydrolase II: BR73_RS0105545 oxo-L-proline γ-L-glutamyl deoxygluconokinase: ACP S- Asp-tRNA(Asn) sn-glycerol- 5-dehydro- superpathway of pyridoxal 5'-phosphate biosynthesis and salvage synthase ThiC: thiC repair protein MutS: oligoribonuclease/ (uracil(1498)-N(3))- thioribose 1-acyl-sn-glycerol- a fatty acyl-[acyl- sulfur BR73_RS0111895 5-phosphate glutathione BR73_RS0116495 tRNA 2- malonyltransferase: /Glu-tRNA(Gln) 1-phosphate 4-deoxy-D- adenosylcobalamin HMP-P pyroglutamyl- (2E,7Z)- O-acetylhomoserine HAD family HAD family BR73_RS0100280 PAP phosphatase methyltransferase: kinase: 3-phosphate carrier protein] transferase 1-deoxy-L- D-mannonate phosphate thiouridine(34) ornithine fabD amidotransferase: dehydrogenase: glucuronate a butanoyl-[acp] acyl-ACP D-erythrose thiamine diphosphate salvage II peptidase hexadecenoyl-CoA aminocarboxypropyltransferase/ hydrolase: hydrolase: NrnA: BR73_RS0117635 mtnK acyltransferase: LarE: larE a [cysteine glycero-tetrulose ARP KDGP acyltransferase synthase carbamoyltransferase: DNA ACP S- an N 3 - gatB gatA gatC BR73_RS0116715 isomerase: 5-deoxy-α- thioesterase: pyridin-1-ium-3- 4-phosphate a NifDK protein bifunctional I: pcp mannonate cysteine synthase: BR73_RS0119915 BR73_RS0119915 BR73_RS0117835 an L-glutaminyl- BR73_RS0100185 4-phosphate PlsX: plsX argF mismatch malonyltransferase: methyluracil 1498 DHAP kduI D-ribose 1- beta-ketoacyl- desulfurase]-(S- hydroxymethylpyrimidine MnmA: mnmA Gln 3-deoxy-D- BR73_RS0103960 carboxylate-5- containing an M-cluster 4-amino-2-methyl-5- dehydratase: L-idonate degradation BR73_RS0124330 [+ 5 isozymes] [+ 5 isozymes] repair protein a nucleoside 5'- [tRNA ] ACP synthase 1-acyl-sn-glycerol- a fatty acid sulfanyl) -[disordered- D-erythrose- kinase/ a malonyl-fabD in 16S rRNA glycero-2,5- phosphate thiocarboxylate 2 pyrimidinemethanol uxuA monophosphate 6,7-dimethyl-8- 4-phosphate bifunctional MutS: mutS hexodiulosonate II: fabF 3-phosphate form scaffold phosphomethylpyrimidine 5-oxo-L-proline (S)-3-hydroxy-(7Z) 34 [PedD acyl- mononucleotide ribityllumazine dehydrogenase: bifunctional 2-dehydro-3- 4-hydroxy-2- L-idonate an acyl phosphate a [protein]- a 2-thiouridine a (2R)-2- a (2R)-2- a properly matched acyltransferase: ATP- protein] complex kinase: thiD -hexadecenoyl-CoA acetate met acyl-carrier protein a halide anion a halide anion L-citrulline carrier protein] a 3-oxohexanoyl-[acp] synthase: gap hydroxymethylpyrimidine deoxy-D-gluconate oxoglutarate L-cysteine in tRNA hydroxy fatty acid hydroxy fatty acid DNA base pair BR73_RS0101420 dependent S-adenosyl-L-methionine salvage I kinase/ a 1,2-diacyl- BR73_RS0111890 4-phospho- HMP-PP 2-dehydro-3- aldolase/2- sacrificial phosphomethylpyrimidine 5-dehydro- 3-oxoacyl-[acyl- sn-glycerol D-erythronate deoxygluconokinase: dehydro-3-deoxy- sulfur kinase: thiD D-gluconate 4 carrier-protein] 3-phosphate a [cysteine desulfurase]- 6,7-dimethyl-8-(1- erythronate- SAH glu BR73_RS0116495 phosphogluconate 3-oxo-(7Z)- adenine 2503 a [protein]- an O - D-cellobiose an sn-glycero-3- a uridine 38- a [protein]- transferase NADP biosynthesis an acyl-CoA H O a D-tryptophanyl- leukotriene-D4 a holo [BryU acyl- an unfolded reductase: fabG phosphatidate [scaffold protein- D-ribityl)lumazine aldolase: eda gluconate 5- hexadecenoyl-CoA methylthymine 6'-phosphate phospho-N-(acyl) 2 an L-amino acid MEP ser LarE: larE 4-phosphate HMP-P in 23S rRNA L-cysteine [tRNA Trp ] carrier protein] 40 in tRNA L-arginine protein cytidylyltransferase: 1-(5-O-phospho-β- (2Fe-2S)] complex riboflavin KDGP dehydrogenase: in DNA ethanolamine ACP S- RluA family 1-deoxy-D-xylulose- potassium- a (3R)-3- dehydrogenase: 5'-methylthioadenosine/ amino acid protein L-serine BR73_RS0118870 D-ribofuranosyl)-5- synthase: BR73_RS0119905 adenosylhomocysteine bifunctional 5-(2-hydroxyethyl) NAD + D-glyceraldehyde BR73_RS0124410 malonyltransferase: pseudouridine 5-phosphate arginine kinase: chaperonin K + transporting K + hydroxyhexanoyl-[acp] pyruvate 23S rRNA 6-phospho- acyl-CoA thioesterase: membrane racemase: -lyase, a CDP- (sulfanylcarbonyl) ribE nucleosidase: hydroxymethylpyrimidine -4-methylthiazole NAD(+)/ 3-phosphate methylated-DNA-- glycerophosphodiester D-tyrosyl-tRNA(Tyr) fabD synthase: reductoisomerase: BR73_RS0107745 iron-sulfur- GroEL: groL ATPase 3-hydroxyacyl- (3R)-3-hydroxy-2-oxo- bifunctional D-gluconate (adenine(2503)-C(2) beta- BR73_RS0103710 dipeptidase: BR73_RS0106280 diacylglycerol pyridin-1-ium-3- a [co-chaperone]- BR73_RS0102420 kinase/ NADH kinase: periplasmic disulfide bond formation (5Z)-tetradecenoyl-CoA [protein]-cysteine S- phosphodiesterase: deacylase: ACP S- BR73_RS0117940 BR73_RS0118865 a [protein]- dependent: ACP dehydratase riboflavin D-glyceraldehyde 4 phosphooxybutanoate hydroxyethylthiazole )-methyltransferase glucosidase: acyl-CoA thioesterase: BR73_RS0122340 1-deoxy-D- ω carbonyl adenylate [scaffold protein- pyruvate phosphomethylpyrimidine BR73_RS0120435 4-hydroxy-2- methyltransferase: BR73_RS0105105 BR73_RS0103695 [+ 4 isozymes] N -phospho- FabZ: fabZ ATP- 3-phosphate 3-phosphoserine/ S-ribosyl-L- kinase: thiM RlmN: rlmN ascB malonyltransferase: 38- a D-amino acid xylulose 5- sdaAB sdaAA a protein kinase: thiD NADP + a [DsbB protein] a [DsbA protein] two reduced oxoglutarate BR73_RS0103100 BR73_RS0105115 a pseudouridine L-arginine 2+ 2+ (2Fe-2S)] complex bifunctional fabD Ca RS0112415 Ca CDP-diacylglycerol dependent phosphohydroxythreonine homocysteine 4-methyl-5-(2- an electron- with reduced L- carrying a cysteine residues aldolase/2- a malonyl- 40 in tRNA phosphate pyruvate a (2E)-hex-2-enoyl-[acp] biosynthesis II sacrificial riboflavin kinase/ 1-deoxy-D- phosphooxyethyl) transfer quinone D-gluconate leukotriene-E4 transaminase: serC HMP-PP cysteine residues disulfide bond in a protein dehydro-3-deoxy- 2503 D-glucopyranose sn-glycerol an N- gly [BryU acyl- FAD synthetase: 6-phosphate a 2-methyladenine a [protein]-S- D-glucopyranose a tRNA Trp sulfur xylulose-5- 4-phosphooxy- S-ribosylhomocysteine thiazole phosphogluconate (2E,5Z)- 5'-deoxyadenosine met a thymine in DNA 6-phosphate 3-phosphate acylethanolamine a carboxylate D-tryptophan carrier protein] BR73_RS0117825 in 23S rRNA methyl-L-cysteine DHAP transferase a [chaperone-ATP]- phosphate L-threonine lyase: aldolase: eda tetradecenoyl-CoA + + NAD(P)H- LarE: larE [co-chaperone]- synthase: thiamine Na RS0113785 Na a [LarE]-S-[1-(5-O FMN BR73_RS0119920 dependent glycerol- [scaffold protein- dxs phosphate -phosphono-β-D- D-glyceraldehyde 6 an O - a 2'- 3 5-fluorouridine 5'- a SpoIVB 3-phosphate (2Fe-2S)] complex bifunctional synthase: thiE pyruvate a 2-oxo a [protein]- an N -methyladenine a [protein] N-terminal- sn-glycerol a holo [BryP acyl- a [protein]- (S)-4-amino-5- a hexanoyl-[acp] ribofuranosyl)-5- 3-amino-1- 3-phosphate methylguanine deoxyribonucleoside a tRNA precursor monophosphate a protein asn peptidase dehydrogenase: riboflavin kinase/ pyridoxine 1-deoxy-D- AI-2 L-homocysteine (3E,5Z)-tetradeca- (S)-3-hydroxy-(5Z) carboxylate L-cysteine [DNA] in DNA formyl-L-methionine 3-phosphate carrier protein] L-histidine oxopentanoate (sulfanylcarbonyl) hydroxyacetone in DNA 5'-triphosphate CTP noncanonical glutamate-1- Precursor BR73_RS0113255 FAD synthetase: xylulose 5- 3,5-dienoyl-CoA -tetradecenoyl-CoA ACP S- histidine kinase: beta-ketoacyl- sn-glycerol pyridin-1-ium-3- 1-phosphate pyridoxamine thiamine phosphate pyrimidine amino acid semialdehyde SpoIVB BR73_RS0117825 phosphate 5-methyltetrahydropteroyltriglutamate- malonyltransferase: GPR endopeptidase: BR73_RS0121040 ACP synthase 3-phosphate carbonyl]-L-cysteine pyridoxamine acyl-CoA 2-oxoacid:ferredoxin methylated-DNA-- DNA-3- peptide glycerol-3-phosphate nucleotidase, racemase: 2,1- peptidase: a [chaperone- pyridoxamine - homocysteine S-methyltransferase: DNA polymerase IV: fabD BR73_RS0117680 [+ 3 isozymes] II: fabF ATP- an [2Fe-2S] kinase: Nucleoside and Nucleotide Degradation thioesterase: [protein]-cysteine S- ribonuclease Z: methyladenine deformylase: def cytidylyltransferase: YjjG family: BR73_RS0106280 a [protein]- aminomutase: spoIVB glycerol-3- ADP]-[disordered- FAD kinase: BR73_RS0105180 BR73_RS0126080 ACP S- dependent cluster protein BR73_RS0113265 BR73_RS0103710 subunit beta: methyltransferase: BR73_RS0104225 glycosylase I: peptide tagD BR73_RS0116990 N-phospho- hemL a SpoIVB a 3-oxooctanoyl-[acp] phosphate 1-O- form scaffold BR73_RS0113265 3-oxo-(5Z)- [+ 9 isozymes] malonyltransferase: a peptide D-asparagine sacrificial acyl-CoA BR73_RS0119845 BR73_RS0111170 deformylase: def peptidase acyltransferase protein] complex met folate transformations III (E. coli) purine nucleobases degradation II (anaerobic) tetradecenoyl-CoA BR73_RS0103100 fabD 5-fluorouridine L-histidine 5-aminolevulinate sulfur pyridoxine pyridoxamine thiamine diphosphate DsbA family superpathway of pyrimidine superpathway of pyrimidine thioesterase: a malonyl- 3-oxoacyl-[acyl- PlsY: plsY pyridoxal deoxyribonucleosides degradation a single-stranded [BryP acyl- a 1-acyl-sn transferase 5'-phosphate 5'-phosphate oxidoreductase: ribonucleosides degradation BR73_RS0105115 a reduced [DNA] mature tRNA an apurinic site CDP-glycerol carrier-protein] heme b biosynthesis II methionine a tetrahydrofolate an acyl-CoA CO H + a guanine in DNA a [protein]-S- oligoribonucleotide 3-methyladenine formate an N-terminal L- carrier protein] -glycerol 3- LarE: larE BR73_RS0116825 2'-deoxycytidine (3E,5Z)- 2 ferredoxin [iron- within DNA reductase: fabG pyridin-1-ium-3,5- (oxygen-independent) adenosyltransferase: a [DsbB protein] a [DsbA protein] purine cytidine methyl-L-cysteine methionyl-[protein] phosphate an [Fe-S cluster pyridoxamine 5''- pyridoxamine 5''- pyridoxamine an electron- an intra- tetradecadienoate (3Z)-dodec- sulfur] cluster bisthiocarboxylate BR73_RS0101570 carrying a with reduced L- nucleoside deaminase: a (3R)-3- 1-acyl-sn-glycerol- biosynthesis phosphate oxidase: phosphate oxidase: kinase: dihydrofolate reductase: transfer quinol protein disulfide nucleoside 3-enoyl-CoA mononucleotide uroporphyrinogen-III methionine disulfide bond cysteine residues BR73_RS0119280 hydroxyoctanoyl-[acp] 3-phosphate chaperone]-ATP BR73_RS0102640 BR73_RS0102640 BR73_RS0113265 BR73_RS0123305 deaminase: adenosyltransferase: xanthine [+ 2 isozymes] enoyl-CoA a mature peptidoglycan 34 a thiocarboxylated a 2'- UDP-N-acetyl- UDP a [protein] (n) a uridine an N-acylated- 3-hydroxyacyl- acyltransferase: dihydrofolate reductase: BR73_RS0119280 thymidine uridine hydratase/ (meso-DAP containing) [SAMP] C- deoxyribonucleoside glycerophosphoserine coenzyme A VibB a tripeptide quercitrin α-D-glucosamine a dipeptide (L-serine/L- selenide BR73_RS0109770 dehydrogenase: in tRNA [DNA] D-amino acid GTP ribonucleotide- ACP dehydratase BR73_RS0100185 BR73_RS0100450 BR73_RS0104415 [+ 2 isozymes] isomerase: terminal glycine 5'-triphosphate UDP-N- membrane threonine) selenide, FabZ: fabZ pyridin-1-ium- coproporphyrinogen III PLP pyrimidine/purine pyrimidine/purine acetylglucosamine diphosphate 1-acyl-sn-glycerol- SAM Fermentation N 6 -L-threonylcarbamoyladenosine 37 BR73_RS0110455 dipeptidase: phosphatestage II water 3-thioamide-5- bis(guanylyl molybdopterin) serine [+ 3 isozymes] hypoxanthine nucleoside endolytic transglycosylase glycerophosphodiester alpha-L- diguanylate cyclase: reductase: 3-phosphate adenosylcobalamin phosphopantothenate biosynthesis I a 7,8-dihydrofolate a 5-methyltetrahydrofolate -modified tRNA biosynthesis 2'-deoxyuridine nucleoside (2E)-dodec- tRNA 2- DNA polymerase IV: holo-[acyl- peptidase 2-epimerase (non- BR73_RS0122340 sporulation dikinase a (2E)-oct-2-enoyl-[acp] thiocarboxylate cofactor sulfurylation oxygen-independent hydroxymethyltransferase: phosphorylase: MltG: mltG phosphodiesterase: D-aminoacylase: rhamnosidase: BR73_RS0120150 BR73_RS0124580 acyltransferase: biosynthesis from adeninyl adenosylcobamide homolactic fermentation phosphorylase: 2-enoyl-CoA thiouridine(34) BR73_RS0126080 carrier-protein] T: pepT hydrolyzing): protein SelD: selD mononucleotide coproporphyrinogen 3-methyl-2- BR73_RS0122805 BR73_RS0118425 guanosine lytic transglycosylase BR73_RS0105105 BR73_RS0104450 BR73_RS0122355 a proteinogenic [+ 7 isozymes] BR73_RS0124585 BR73_RS0101420 adenosylcobinamide-GDP I biosynthesis from 8-hydroxypurine BR73_RS0118425 synthase synthase: acpS BR73_RS0115795 E: spoIIE Ni pincer complex III oxidase: oxobutanoate thymidylate thr pyrimidine-nucleoside nucleotides domain-containing [+ 9 isozymes] UDP-N-acetyl-α- amino acid c-di-GMP selenophosphate a 1,2-diacyl- cys adenosylcobinamide-GDP a (6S)-5-formyltetrahydrofolate xanthine pyrimidine- MnmA: mnmA dUDP a [protein] Ser/Thr BR73_RS0117665 5,6-dimethylbenzimidazole bifunctional D-glucopyranose threonylcarbamoyl- phosphorylase: degradation III protein: BR73_RS27200 β D-mannosamine sn-glycerol synthase: thyA dehydrogenase: nucleoside a proteinogenic -L- coproporphyrinogen nicotinate D- bifunctional homocysteine methylenetetrahydrofolate5-formyltetrahydrofolate AMP synthase: BR73_RS0118530 sn-glycerol a holo-[VibB aryl- a dipeptide quercetin 3-phosphate cysteine desulfurase: BR73_RS0104415 (S)-3- 34 ser 3',5'-ADP a carboxylate rhamnopyranose adenine S-methyltransferase/ dehydrogenase/ ROK family phosphorylase: a [SAMP] C- a 2-thiouridine [DNA] 3-phosphate carrier protein] a D-amino acid amino acid phosphatidate BR73_RS0117630 dehydrogenase ribonucleotide:5,6- cyclo-ligase: (L-threonylcarbamoyl)BR73_RS0103645 GMP hydroxydodecanoyl-CoA a mature peptidoglycan GlcNAc-1,6-anhMurNAc- an octanoyl-[acp] methylenetetrahydrofolate glucokinase: [+ 3 isozymes] pyrimidine/purine BR73_RS0118530 uracil (n) terminal glycine in tRNA HemZ: hemZ dimethylbenzimidazole methenyltetrahydrofolateBR73_RS0118610 γ cytidylyltransferase: [+ 4 isozymes] 2-dehydropantoate BR73_RS0125585 adenylate (meso-DAP containing) L-Ala- -D-Glu-DAP-D-Ala an [L-cysteine phospho-D- reductase: BR73_RS0122430 cyclohydrolase FolD: folD nucleoside thymine beta-ketoacyl- BR73_RS0118870 protoporphyrinogen IX a 5,10-methylenetetrahydrofolate a 5,10-methenyltetrahydrofolate D-glucopyranose tRNA (adenosine(37)-N6)- phosphorylase: ACP synthase desulfurase]-S- ribosyltransferase: ketopantoate adenine ribotide threonylcarbamoyltransferase a ring-opened 7- N-acetyl-β-D-glucosamine- a CDP- 6-phosphate BR73_RS0118425 a [protein]- a DNA methyl all-trans- a guanine 46 dCDP sulfanyl-L-cysteine BR73_RS0105500 reductase: bifunctional guanosine glycerophosphoglycerol rutin A NADPH H + an adenine in DNA roseoflavin acetylene II: fabF diacylglycerol bis(guanylyl α-ribazole phosphate complex: tsaE tsaB tsaD pyrimidine- 5,6-dihydrouracil 3-oxododecanoyl-CoA methylguanine L-cysteine phosphotriester 4-hydroxybenzoate octaprenyl 1,6-anhydro-N- in tRNA thr a protein cysteine desulfurase: BR73_RS0109780 glucose-6-phosphate 6 6,8- β ribonucleotide- molybdopterin) 5'-phosphate methylenetetrahydrofolate an N -L- in DNA diphosphate acetyl- -D-muramate DNA adenine tRNA bifunctional endopeptidase nitrogenase BR73_RS0117630 isomerase: 37 dihydroxypurine nucleoside diphosphate a 3-oxodecanoyl-[acp] cofactor β-alanine adenosylcobinamide- dehydrogenase/ threonylcarbamoyladenine pyrimidine/purine methylase: (guanosine(46)-N7) threonine riboflavin kinase/ iron [+ 4 isozymes] adenosylcobinamide- (R)-pantoate BR73_RS0102435 phosphorylase: dihydropyrimidinase: glycerophosphodiester alpha-L- NADPH reductase: La: lon protoporphyrin IX GDP molybdopterin biosynthesis methenyltetrahydrofolate in tRNA nucleoside methylated-DNA-- BR73_RS0119545 -methyltransferase ammonia-lyase: FAD synthetase: protein: nifH a [bis(guanylyl GDP xanthine BR73_RS0118530 hydA formamidopyrimidine- 4-hydroxybenzoate phosphodiesterase: beta- rhamnosidase: dehydrogenase BR73_RS0124580 endopeptidase 3-oxoacyl-[acyl- ribazoletransferase: cyclohydrolase FolD: folD phosphorylase: [protein]-cysteine S- TrmB: trmB BR73_RS0116380 BR73_RS0117825 molybdopterin) F6P DNA glycosylase: octaprenyltransferase: hexosaminidase: DNA adenine an N 7 - La: lon [+ 2 isozymes] carrier-protein] ribazoletransferase: 2-methyladeninyl BR73_RS0105510 dehydrogenase: 3-ureidopropanoate BR73_RS0118425 decanoyl-CoA methyltransferase: BR73_RS0105105 BR73_RS0122355 NamA: namA roseoflavin BR73_RS0124585 biotin-carboxyl carrier protein assembly cofactor [bis-MGD cofactor Coα-[α-(adenin- 10 BR73_RS0102945 BR73_RS0120760 BR73_RS0111405 methylase: 46 2-oxobutanoate ethene reductase: fabG BR73_RS0105510 adenosylcobamide biosynthesis an N -formyltetrahydrofolate BR73_RS0104415 [+ 2 isozymes] BR73_RS0103100 methylguanine 5'-phosphate CDP a peptide chaperone]-S- chaperone]- 9-yl)]-Coβ- GTP 6-phosphofructokinase: BR73_RS0108760 from adenosylcobinamide-GDP β 6 in tRNA a (3R)-3- adenosylcobalamin cys ATP pfkA [+ 3 isozymes] guanine -L- quercetin- an N -methyladenine a [biotin carboxyl- sulfanyl-L-cysteine bis-MGD adenosylcobamide a [DNA]- 2,6-diamino-4- glycerol sn-glycerol + protoheme 5'-phosphate (R)-pantothenate NADPH repair (prokaryotes) guanine a 5'-phospho- 4-hydroxy-3- 1,6-anhydro-N- rhamnopyranose A(H2) NADP hydroxydecanoyl-[acp] carrier protein]-L-lysine 2-methyladenine 5'-phosphate GTP 3',8- β-D-fructose 1,6- nucleotide- hydroxy-5-(N-methyl) 4-oxo-2-pentenal a [protein]-S- 3-phosphate GlcNAc 3-glucoside in DNA cysteine desulfurase: [DNA] [DNA] octaprenylbenzoate acetyl-β-muramate 3-hydroxyacyl- biotin--[acetyl-CoA- type III pantothenate cyclase bisphosphate urate α 3'-phosphate formamidopyrimidine methyl-L-cysteine BR73_RS0117630 uracil 2-deoxy- -D- β-alanine (2E)-dec-2-enoyl-CoA ACP dehydratase carboxylase] ligase: kinase: MoaA: moaA NADPH ribose 1-phosphate guanine BR73_RS0104760 [+ 4 isozymes] (8S)-3',8-cyclo-7,8- guanine FabZ: fabZ BR73_RS0104700 sulfo-bis(guanylyl 2-methyladenine Coα-[α-(adenin- class II deaminase: guaD β thiamine thiamine diphosphate an [L-cysteine a carboxy-adenylated dihydroguanosine xanthine deaminase: a 7,8-dihydro- a [Co(II) proline a 2,3,4-saturated sn-glycero-3- -D-galactopyranosyl- N-acetyl-9-O- β-D-fructofuranose 37 D-ribose 5- a [biotin carboxyl- molybdopterin) adenosylcobalamin (R)-4'- β fructose-1,6- A(H) a ribonucleoside guanine diphosphate biosynthesis III ribotide phosphate 7-yl)]-Co - desulfurase]-S- [small subunit of dehydrogenase: guaD 8-oxoguanine betaine-specific 1,2-diacyl-sn- (1->3)-N-acetyl- Phe ethylphosphate precorrin-6B oxaloacetate a (2E)-dec-2-enoyl-[acp] carrier protein]-N cofactor 5'-triphosphate xanthine phosphoethanolamine acetylneuraminate 1-phosphate triphosphate in tRNA a protein phosphate biosynthesis (Staphylococcus) phosphopantothenate adenosylcobamide sulfanyl-L-cysteine molybdopterin synthase] bisphosphate BR73_RS0104415 (S)-3- in DNA corrinoid protein] glycerol 3-phosphate CTP D-glucosamine tRNA precorrin-6y C5,15- citrate/2- ribose 5- 6 -biotinyl-L-lysine cyclic pyranopterin 2-deoxy-D-ribose ribonucleoside alkaline ATP- I (E. coli) adenosylcobinamide- aldolase: fba hydroxydecanoyl-CoA (guanosine(37)-N1) methyltransferase methylcitrate phosphate HMP-PP monophosphate (R)-NADPHX [+ 3 isozymes] 5-phosphate xanthine triphosphate phosphatase: dependent zinc HMP-PP GDP bifunctional DUF4445 domain- glycerophosphodiester sialate O- class II fructose- -methyltransferase (decarboxylating) synthase: isomerase thiamine synthase dehydrogenase: formamidopyrimidine- phosphatidate 1,3-beta-galactosyl- reductase: BR73_RS0116520 metalloprotease thiamine ribazoletransferase: ADP-dependent containing protein: phosphodiesterase: acetylesterase: 1,6-bisphosphate TrmD: trmD subunit CbiE: cbiE BR73_RS0106770 B: rpiB phosphate benzimidazolyl adenosylcobamide MoaC: moaC triose-phosphate deoxyribose- BR73_RS0104415 DNA glycosylase: cytidylyltransferase: N-acetylhexosamine BR73_RS0123355 an N 1 - FtsH: hflB a [biotin carboxyl- phosphate thiamine NAD salvage pathway II (PNC IV cycle) BR73_RS0105510 a thiocarboxylated NAD(P)H-hydrate BR73_RS0107910 BR73_RS0105105 BR73_RS0111200 aldolase: fba ethanol (2S,3S)-2- D-ribulose synthase: biosynthesis from adenosylcobinamide-GDP thioredoxin Coα-[α-(2- isomerase: [+ 3 isozymes] BR73_RS0102945 BR73_RS0118870 phosphorylase: gnpA [+ 2 isozymes] methylguanine 37 precorrin-8x a decanoyl-[acyl-carrier protein] carrier-protein dimer]- synthase: diphosphate [small subunit of cyclic pyranopterin phosphate a 2'- methylcitrate a peptide 5-phosphate methyladenin-9-yl)]-Co tetrahydrofolate salvage from BR73_RS0120360 dehydratase/ 3-oxodecanoyl-CoA Phe 6 thiE pathway phosphate D-glyceraldehyde aldolase: deoxyribonucleoside in tRNA N -biotinyl-L-lysine thiE biosynthesis thiamine + β molybdopterin synthase] DHAP NAD(P)H-hydrate urate a [Co(I) proline benzimidazole NAD -adenosylcobamide 5,10-methenyltetrahydrofolate 3-phosphate xanthine deoC a [DNA]- A ethanolamine sn-glycerol α acetate N-acetylneuraminate DHAP D-glyceraldehyde beta-ketoacyl- acetyl-CoA thiamine II (Bacillus) NAD(+) epimerase: a 5'-phospho- 7,8-dihydro- betaine-specific a CDP-2,3,4-saturated- -D-galactose 5'-triphosphate phosphate an oxidized 5'-phosphate cytidylyl molybdenum nucleotide- 4-oxo-2-pentenal 3-phosphate GlcNAc ACP synthase carboxylase phosphate HMP-PP diphosphatase: a 5,10- type I BR73_RS0119325 [DNA] 8-oxoguanine corrinoid protein] diacylglycerol 1-phosphate thioredoxin cofactor sulfurylation D-glyceraldehyde 3'-phosphate II: fabF carboxyltransferase thiamine benzimidazole nudC methenyltetrahydrofolate glyceraldehyde- acetaldehyde acetyl-CoA bifunctional (S)-NADPHX 3-phosphate subunit beta: phosphate ribotide phosphate cytidylyl molybdenum 3-phosphate octanoyl-CoA a 3-oxododecanoyl-[acp] carboxylase biotin synthase: NAD(+) synthase: Coα-[α-(2- methylenetetrahydrofolate molybdopterin cofactor (trioxo) BR73_RS0106725 thioredoxin- dehydrogenase: bifunctional 5-ureidoimidazole- bifunctional S-methyl-5'- UDP-N-acetyl- decaprenyl-diphospho-N- a single RNase R degradation a DNA containing DNA combined with N-acetyl-4-O- 4-(cytidine 5'- a guanine 37 carboxylase subunit: thiamine thiE thiamine adenosylcobinamide- BR73_RS0106120 methyladenin-7-yl)]-Co dehydrogenase/ α canavaninosuccinate sn-glycerol D-glycerate oxaloacetate precorrin-6B disulfide gap ADP-dependent 4-carboxylate acetaldehyde- thioadenosine degradation I -D-glucosamine acetylmuramoyl-pentapeptide stranded DNA substrate RNA an apurinic/ exogenous DNA to form acetylneuraminate diphospho)-2-C- in tRNA repressor LexA 3-oxoacyl-[acyl- acetyl-CoA BR73_RS0106720 diphosphate thiamine GDP nicotinate adenine β-adenosylcobamide methenyltetrahydrofolate 3-phosphate thiamine NMN reductase: an [MCD cofactor type I NAD(P)H-hydrate CoA/alcohol apyrimidinic site a recombinational Hollidayjunction junction methyl-D-erythritol4-(cytidine 5'- tRNA 2-hydroxy-3- citrate/2- precorrin-6A carboxylase, phosphate ribazoletransferase: dinucleotide 10 cyclohydrolase FolD: folD S-methyl-5'- L-glyceraldehyde carrier-protein] an N - chaperone]-MCD dehydratase/ dehydrogenase: undecaprenyldiphospho- (guanosine(37)-N1) oxopropionate methylcitrate transcriptional carboxyltransferase diphosphokinase: trxB glyceraldehyde- thioadenosine exodeoxyribonuclease resolvase sialate O- diphospho)- 3-phosphate reductase: reductase: fabG BR73_RS0105510 formyltetrahydrofolate adhE 5'-methylthioadenosine/ (2E)-oct-2-enoyl-CoA muramoylpentapeptide beta-N- ribonuclease argininosuccinate -methyltransferase reductase: synthase: repressor subunit beta: accD BR73_RS0118360 Coα-[α-(benzimidazolyl) demethylmenaquinol- thiamine diphosphate cysteine desulfurase: 3-phosphate NAD(P)H-hydrate RuvX: ruvX acetylesterase: 2-C-methyl-D- reductase: mgrA cobK adenosylhomocysteine VII: xseB endonuclease LexA: lexA a (3R)-3- β phosphoribosylglycinamide BR73_RS0117630 dehydrogenase: epimerase: 5-aminoimidazole- acetylglucosaminyltransferase: R: rnr lyase: argH erythritol kinase: 1 TrmD: trmD BR73_RS0124900 BR73_RS0106770 a [carboxyl-carrier thiamine ]-Co -adenosylcobamide 8 biosynthesis II salvage III ammonium acetyl-CoA BR73_RS0120460 III: nth Holliday junction BR73_RS0111200 an N - L-glyceraldehyde tartronate 6 nicotinate-nucleotide acyl carrier formyltransferase: nucleosidase: BR73_RS0102410 cleaved precorrin-6A hydroxydodecanoyl-[acp] protein dimer]-N - 5'-phosphate a reduced [+ 4 isozymes] gap BR73_RS0119325 4-carboxylate BR73_RS0101450 methylguanine 37 3-phosphate citrate thiamine diphosphate adenylyltransferase: protein all-trans- BR73_RS0102420 resolvase RecU: 2-phospho-4-(cytidine semialdehyde repressor LexA 3-hydroxyacyl- carboxybiotinyl-L-lysine thioredoxin BR73_RS0107715 1,4-dihydroxy- thiamine a [cytidylyl molybdenum in tRNA diphosphate BR73_RS0115925 activation octaprenyl NADPH MTR a nucleoside 5'- resolution of recombinationalBR73_RS0117935 5'-diphospho)-2-C- ACP dehydratase 6-naphthoate thiamine cofactor chaperone]- 13-DPG (S)-3- decaprenyl-pyrophosphoryl- a ribonucleoside a single-stranded a diribonucleotide a 3'-terminal a 5'-phospho- acetate N-acetylneuraminate L-canavanine fumarate NaMN a tetrahydrofolate diphosphate UDP monophosphate junction formation methyl-D-erythritol FabZ: fabZ an apo acyl- diphosphokinase: cytidylyl molybdenum hydroxyoctanoyl-CoA (N-acetylglucosamine)-N- 5'-monophosphate oligodeoxyribonucleotide unsaturated sugar [DNA] α α S-methyl-5- of two intact strands Co -[ -(benzimidazolyl) carrier protein menaquinone BR73_RS0118360 cofactor (sulfo-dioxo) phosphoglycerate Hydrogen Production 4-aminoimidazole acetylmuramyl-(pentapeptide) β holo-[acyl- thiamine thioribose a (2E)-dodec-2-enoyl-[acp] ]-Co -adenosylcobamide carrier- biosynthesis diphosphate kinase: pgk kinase: mtnK decarboxylase: protein] 3-phospho- hydrogen production III 10 NADH repair (prokaryotes) an L-methionyl- an N - 5-amino-4- sucrose a single- a ribonucleoside a [protein]-α- (R)-10- phosphoenol synthase: BR73_RS0120765 D-glycerate 5-MTR-1-P 3-oxooctanoyl-CoA PRPP dioscin a uracil in DNA a [protein] Ser/Thr D-glycerate oxaloacetate histidinol [initiator tRNA Met ] formyltetrahydrofolate imidazolecarboxyamide stranded RNA diphosphate L-glutamate Hydroxystearate pyruvate acpS a reduced 3,5-dihydro-4H- serine/threonine protein-glutamate O- 2-hydroxy-3- oxaloacetate a holo acyl- 2,3-bisphosphoglycerate- ribonucleotide- histidinol NADH ferredoxin [iron- imidazol-4-one protein kinase: methyltransferase oleate hydratase: oxopropionate decarboxylase pyruvate carrier protein demethylmenaquinol-8 independent adenine alpha-L- sucrose polyribonucleotide uracil-DNA diphosphate dehydrogenase: a dodecanoyl-[acp] sulfur] clusterech hydrogenase superpathway of purine deoxyribonucleosides degradation BR73_RS0103625 CheR: BR73_RS0121955 reductase: subunit alpha: kinase: pyk phosphoglycerate methionyl-tRNA phosphoribosyltransferase: rhamnosidase: phosphorylase: nucleotidyltransferase: glycosylase: reductase: hisD subunit D: BR73_RS0116410 BR73_RS0124900 BR73_RS0116330 Amino Acid Biosynthesis mutase: hexanoyl-CoA formyltransferase: BR73_RS0107855 BR73_RS0122355 gtfA BR73_RS0116755 BR73_RS0119235 anti-sigma F factor: BR73_RS0124580 a [protein]-L- BR73_RS0105325 oleate tartronate his pyruvate BR73_RS0120355 H BR73_RS0118400 BR73_RS0106440 a 2'- BR73_RS0124585 glutamate-O 5 pyruvate beta-ketoacyl- acyl-ACP 2 2'-deoxyguanosine semialdehyde Aromatic Compound Biosynthesis N-formimino- α a [protein] (L-serine/L- -methyl-ester ACP synthase thioesterase: L-histidine biosynthesis superpathway of L-serine cofactor- β β -D- uracil deoxyribonucleoside superpathway of branched chain amino acid biosynthesis L-arginine biosynthesis II (acetyl cycle) L-isoleucine superpathway of L- (R)-NADHX glycine 2'-deoxyadenosine an N-formyl- 3-O- -D-glucosyl- L-rhamnopyranose -D-fructofuranose a nucleoside a single- an apyrimidinic threonine) phosphate II: fabF BR73_RS0103960 and glycine biosynthesis I independent bifunctional AICAR glucopyranose 5'-diphosphate biosynthesis IV asparagine biosynthesis chorismate biosynthesis I L-methionyl- a tetrahydrofolate diosgenin diphosphate stranded RNA site in DNA PRPP phosphoglycerate ADP-dependent 1-phosphate N-acetylglutamyl- 3-phospho- dipicolinate biosynthesis pyrimidine/purine (2E)-hexenoyl-CoA [initiator tRNA met ] pyruvate mutase: NAD(P)H-hydrate laurate thr phosphate propanoate D-glycerate asp D-erythrose nucleoside a 3-oxotetradecanoyl-[acp] ATP phosphoglycerate BR73_RS0104035 dehydratase/ acetolactate 4-phosphate a 5-formiminotetrahydrofolate phosphorylase: phosphoribosyltransferase dehydrogenase: 3-deoxy-7- asp NAD(P)H-hydrate UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N D-glyceraldehyde D-sedoheptulose a 3-O-acetylated a [DNA]-3'- an N-terminal L- a [release factor]- a double (5R)-5-benzyl- 3-oxoacyl-[acyl- threonine synthase N-acetyl- 2-phospho- BR73_RS0118425 NADP + coenzyme A naringin a uridine in tRNA a DNA segment D-glucopyranose stearate biosynthesis regulatory subunit: hisZ BR73_RS0110135 phosphoheptulonate aspartate kinase: epimerase: -acetylmuramoyl-L-alanyl-γ- 3-phosphate 7-phosphate rhamnogalacturonan I hydroxyl alanyl-[S18 protein L-glutamine L-homoserine stranded DNA hydantoin carrier-protein] ammonia-lyase: small bifunctional gamma- propanoyl-CoA aspartate-- asparagine D-glycerate pyrimidine/purine [+ 2 isozymes] (S)-3- II (bacteria and plants) ATP synthase: aroF BR73_RS0104040 BR73_RS0119325 2'-deoxyinosine D-glutamyl-L-lysyl- D-alanine of 30S ribosome]ribosomal protein peptide chain DNA/RNA Asp/Glu/hydantoin tRNA xylose reductase: fabG BR73_RS0116380 subunit: ilvN glutamate N- glutamyl- phosphoglycerate ammonia ligase: synthase phosphopyruvate (S)-NADHX nucleoside hydroxyhexanoyl-CoA homoserine O- recombinase lauroyl-CoA phosphoribosyltransferase: dehydrogenase: 3-deoxy-7- aspartate kinase: undecaprenyldiphospho- rhamnogalacturonan alpha-L- S18-alanine N- release factor nuclease racemase: dihydrouridine isomerase: (2Z)-2-aminobut- [+ 2 isozymes] acetyltransferase/ phosphate 2-oxoacid:ferredoxin BR73_RS0112980 (glutamine- hydratase: phosphorylase: transketolase: CoA-disulfide succinyltransferase: RecA: recA a (3R)-3- BR73_RS0117885 phosphoheptulonate BR73_RS0108610 a 5,10- muramoylpentapeptide beta-N- acetylesterase: exodeoxyribonuclease rhamnosidase: acetyltransferase: N(5)-glutamine SfsA: sfsA BR73_RS0114880 synthase xylA a palmitoyl-[acp] 2-enoate amino-acid reductase: oxidoreductase BR73_RS0114225 asparagine hydrolyzing) BR73_RS0119970 bifunctional BR73_RS0118425 BR73_RS0113020 reductase: metA hydroxytetradecanoyl-[acp] acetylglutamate 3-phosphooxypyruvate synthase: L-aspartyl- methenyltetrahydrofolate pyrimidine/purine acetylglucosaminyltransferase: BR73_RS27255 III: xth BR73_RS0122355 rimI methyltransferase: DusB: dusB a DNA segment beta-ketoacyl- 1-(5-phospho- (S)-2-acetolactate acetyltransferase argC subunit beta: synthase : asnB phosphopyruvate ADP-dependent [+ 2 isozymes] [+ 2 isozymes] BR73_RS0122175 an N-terminal N-acetyl- a 5'-phosphooligonucleotide (5S)-5-benzyl- a 5,6-dihydrouridine keto-D-fructose β kinase: argB 4-phosphate nucleoside prmC O-succinyl-L- in reverse ACP synthase -D-ribosyl)-ATP BR73_RS0119845 BR73_RS0118535 BR73_RS0102410 L-alanyl-[S18 protein 5 hydantoin 3-hydroxyacyl- ArgJ: argJ 3-phosphoserine/ (glutamine- 3-deoxy- hydratase: NAD(P)H-hydrate phosphorylase: 3-oxohexanoyl-CoA a [release factor]-N homoserine in tRNA orientation II: fabF ketol-acid glu N-acetyl-L-glutamate bifunctional bifunctional a rhamnogalacturonan a 2'- β-L- of 30S ribosome] ACP dehydratase a 3-oxooctadecanoyl- bifunctional N-acetyl-L-glutamate phosphohydroxythreonine hydrolyzing) D-arabino- aspartate- BR73_RS0123690 dehydratase/ BR73_RS0118425 D-ribose 5- D-xylulose a [DNA]-3'- prunin -methyl-L-glutamine reductoisomerase: 5-semialdehyde 2-oxobutanoate asn methylenetetrahydrofolate methylenetetrahydrofolate ditrans,octacis-undecaprenyldiphospho- UDP + acetate deoxyribonucleoside FabZ: fabZ [acp] phosphoribosyl- 2-iminobutanoate gln : asnB heptulosonate semialdehyde NAD(P)H-hydrate CoA-disulfide NADPH H type I hydroxyl rhamnopyranose ilvC N-acetylornithine transaminase: serC phosphoenol dehydrogenase/ dehydrogenase/ [+ 2 isozymes] N-acetyl-(N-acetylglucosaminyl)muramoyl- phosphate 5-phosphate 5'-monophosphate AMP acetolactate 7-phosphate dehydrogenase: epimerase: a (2E)-tetradec-2-enoyl-[acp] 3-oxoacyl- (2R)-2,3- aminotransferase: O-phospho- pyruvate methenyltetrahydrofolate methenyltetrahydrofolate L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine cyclohydrolase/ carbamoyl- bifunctional synthase small L-threonine 3-dehydroquinate asd BR73_RS0119325 2-deoxy-α-D-ribose 1-phosphate [acyl-carrier- dihydroxy-3- BR73_RS0120120 L-serine cyclohydrolase FolD: folD cyclohydrolase FolD: folD phosphoribosyl- phosphate glutamate N- asn biosynthesis pyruvate butanoyl-CoA protein] methylbutanoate subunit: ilvN synthase: aroB L-aspartate 4- ATP synthase: carB acetyltransferase/ kinase: pyk NADH a [formate C a cytidine 1402 an [RNA]-3'- a D-5- γ-glutamyl- (2R,3S)-3- a phosphate reductase: dihydroxy-acid [+ 2 isozymes] semialdehyde an N 10 - a 5,10- H + hydrogencarbonate nicotinate PRPP FMN NAD(P)H H + a ribonucleoside a single DNA with lesion diphosphatase 2-oxobutanoate BR73_RS0123250 amino-acid 3-dehydroquinate acetyltransferase]-glycine a reduced flavodoxin SAM dGMP in 16S rRNA ribonucleoside- monosubstituted isopropylamide isopropylmalate monoester fabG dehydratase: (S)-2-aceto-2- L-homoserine pyruvate formyltetrahydrofolate methylenetetrahydrofolate triphosphate stranded DNA HisIE: acetyltransferase 4-hydroxy- inosine 5'- 16S rRNA 2',3'- hydantoin ferredoxin: 3-isopropylmalate excinuclease a (3R)-3- acetolactate ilvD carbamoyl phosphate L-ornithine hydroxybutanoate Asp/Glu/hydantoin alkaline a myristoyl-[acp] BR73_RS28405 ArgJ: argJ type II 3- tetrahydrodipicolinate formyltetrahydrofolate serine 2-deoxy-D-ribose 5-phosphate phosphate (cytidine(1402)-2'-O) cyclophosphate BR73_RS0122580 dehydrogenase: ABC subunit hydroxyoctadecanoyl- synthase ser L-lactate pyruvate formate nicotinate 5'-deoxynucleotidase: RNA 2',3'-cyclic racemase: phosphatase: 3-methyl-2- dehydroquinate synthase: deformylase: hydroxymethyltransferase: degradation crotonyl-CoA carbonic anhydrase: flavin reductase: DNA primase: -methyltransferase: [+ 2 isozymes] leuB UvrC: uvrC [acp] 1-(5-phospho-β- small N-acetyl-L-ornithine O-phospho- dehydrogenase: lyase-activating phosphoribosyltransferase: BR73_RS0125925 phosphodiesterase: BR73_RS0114880 BR73_RS0116520 beta-ketoacyl- oxobutanoate dehydratase: aroQ BR73_RS0107250 BR73_RS0107715 BR73_RS0122805 BR73_RS0112465 BR73_RS0126135 BR73_RS0124080 a 2'-O- rsmI an L-5- N-(γ-L-glutamyl) 4-methyl-2- [+ 4 isozymes] 3-hydroxyacyl- D-ribosyl)-AMP subunit: ilvN serine L-homoserine BR73_RS0121300 deoxyribose-phosphate protein: pflA BR73_RS0101415 an [RNA]-3'-thpR DNA without ACP synthase 4-hydroxy- 1402 monosubstituted an alcohol ACP (R)-2,3-dihydroxy- hydroxymethyltransferase: 3-dehydroshikimate formate aldolase: deoC IMP methylcytidine ribunucleoside- -L-alaninol oxopentanoate lesion II: fabF bifunctional [+ 2 isozymes] 2-isopropylmalate branched-chain threonine synthase: tetrahydrodipicolinate (S)-lactate ser 2'-deoxyguanosine hydantoin dehydratase 3-methylpentanoate BR73_RS0122805 IMP in 16S rRNA 2'-phosphate phosphoribosyl- (S)-2-aceto-2- synthase: amino acid BR73_RS0124025 synthase: dehydrogenase: (S)-3- a [formate C acetyltransferase]- CO H O FMNH NAD(P) + ssDNA/pppN(pN) FabZ: fabZ ornithine 5'-deoxyadenosine a flavodoxin semiquinone met 2 2 NaMN 2 a 3-oxohexadecanoyl-[acp] AMP hydroxybutanoate BR73_RS0119370 aminotransferase: dihydroxy-acid BR73_RS0112995 L-serine acetaldehyde D-glyceraldehyde 3-phosphate hydroxybutanoyl-CoA glycin -2-yl radical hybrid carbamoyltransferase: gly guaB n -1 a (2E)-octadec- cyclohydrolase/ ketol-acid 2-isopropylmalate BR73_RS0123295 dehydratase: ilvD (2S,4S)-4- ammonia- argF thr bifunctional XMP 3-oxoacyl-[acyl- 2-enoyl-[acp] phosphoribosyl- reductoisomerase: synthase: leuA (3S)-3-methyl-2- shikimate hydroxy-2,3,4,5- CO lyase, carrier-protein] ATP ammonia assimilation cycle III tetrahydrodipicolinate pyruvate fermentation 2 iron-sulfur- acetaldehyde- fatty acid elongation -- saturated ilvC oxopentanoate UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N-acetylmuramoyl-L- a 3,5,7,9,11,13,15- (2R,3S)-3- reductase: fabG diphosphatase (2S)-2- val shikimate kinase: to ethanol I dependent: CoA/alcohol alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine D-glucopyranose maltopentaose a homogalacturonan NADP + FMNH methyl red [DNA] hepta-oxo- enterobactin D-glucopyranose precorrin-2 N5-CAIR (R)-2,3-dihydroxy- branched-chain dipicolinate acetoacetyl-CoA 2 dAMP isopropylmalate HisIE: isopropylmalate serine racemization ammonium BR73_RS0101585 sdaAB sdaAA dehydrogenase: adhE hexadecanoyl-[PKS-acp] 5-(carboxyamino) a (3R)-3- 3-methylpentanoate L-lysine biosynthesis VI amino acid synthase: dpsA pyruvate undecaprenyldiphospho- DNA polymerase IV: aldo/keto enterochelin glucose 1- 3-isopropylmalate precorrin-2 C(20)- hydroxyhexadecanoyl-[acp] an acetoacetyl-[acp] BR73_RS28405 3-isopropylmalate aminotransferase: shikimate kinase: BR73_RS0117770 2-aminoprop- acetyl-CoA reductase: dehydrogenase: imidazole a stearoyl-[acp] dihydroxy-acid muramoylpentapeptide beta-N- 4-alpha- pectate lyase: FMN-dependent BR73_RS0126080 esterase: dehydratase: methyltransferase: 1-(5-phospho-β-D-ribosyl)- dehydratase: BR73_RS0123295 2-oxoglutarate glu glutamine synthetase: BR73_RS0114150 2-enoate xanthosine flavin reductase: 5'-deoxynucleotidase: BR73_RS27980 BR73_RS0110545 ribonucleotide 3-hydroxyacyl- dehydratase: L-citrulline ser dipicolinate acetylglucosaminyltransferase: glucanotransferase: BR73_RS0114920 NADH-azoreductase: [+ 3 isozymes] BR73_RS0107215 leuD leuC cobI 5-[(5-phosphoribosylamino) leuD leuC asp serine racemase VanT glutamate BR73_RS0114265 formate C- BR73_RS0126135 BR73_RS0125925 a 2'- N-(2,3- D-glucono- mutase: purE ACP dehydratase acyl-ACP ilvD shikimate 3- BR73_RS0102410 malQ BR73_RS0103170 9-hydroxy-3,5,7,11,13,15-[+ 10 isozymes] (2S)-2- methylideneamino]imidazole- aspartate kinase: synthase: gltD gltB acetyltransferase: acetyl-CoA deoxyribonucleoside dihydroxybenzoyl) precorrin-3A thioesterase: argininosuccinate catalytic subunit: vanT ile type I glutamate-- phosphate 1,5-lactone isopropylmalate CAIR FabZ: fabZ 4-carboxamide (3S)-3-methyl-2- 2-isopropylmaleate BR73_RS0104040 pflB pyrimidine/purine 5'-monophosphate hexaoxohexadecanoyl- -L-serine BR73_RS0103960 oxopentanoate synthase: amino acid racemase: [+ 2 isozymes] ammonia ligase: glnA 3-phosphoshikimate 1- an unsaturated 2'-deoxyadenosine [PKS-acp] nucleoside ditrans,octacis-undecaprenyldiphospho-N- a homogalacturonan + a (2E)-hexadec-2-enoyl-[acp] phosphoribosylformimino- 3-isopropylmalate aspartate kinase: BR73_RS0120140 BR73_RS0106280 2-iminopropanoate UDP maltose maltotetraose pectate FMN NADPH H N,N-dimethyl-1,4- a 3-oxoacyl-[acp] branched-chain imidazole glycerol carboxyvinyltransferase: phosphorylase: acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L- anthranilate stearate 5-aminoimidazole dehydratase: BR73_RS0108610 D-serine oligosaccharide phenylenediamine 3-oxoacyl- amino acid L-aspartyl- phosphate aroA acetyl-CoA formate BR73_RS0118425 alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine carboxamide ribotide leuD leuC L-arginino-succinate ammonium gln 5-enolpyruvoyl- [acyl-carrier- isomerase: hisA aminotransferase: 4-phosphate synthase: hisF hisH [+ 2 isozymes] (2R,3S)-3- shikimate 3- bifunctional beta- protein] BR73_RS0123295 argininosuccinate L-proline biosynthesis [+ 8 isozymes] α α phosphoribulosylformimino- isopropylmalate aspartate- phosphate acetaldehyde- xanthine α D-xylulose D-erythrose hydrogen p-nitrophenyl- -L- an (1,5)- an insertion sequence a guanine 527 a [protein]-L- ketoacyl- reductase: lyase: argH I (from L-glutamate) Tetrapyrrole Biosynthesis pyruvate UDP-N-acetyl- -D-muramoyl- D-alanyl-D-alanine D-glucopyranose maltohexaose NADH H + D-glucopyranose precorrin-3B precorrin-4 AICAR-phosphate semialdehyde chorismate CoA/alcohol γ 5-phosphate 4-phosphate peroxide rhamnopyranoside L-arabinan element IS30 in 16S rRNA proline (ω = 180) L-dopa a palmitoyl-[acp] stearoyl-CoA ACP fabG ile 3-isopropylmalate L-alanyl- -D-glutamyl-L-lysine dehydrogenase: synthase: dehydrogenase: xanthine transposase: 16S rRNA peptidylprolyl glucose 1- precorrin-3B C(17)- precorrin-4 C(11)- synthase a (3R)-3- dehydrogenase: arg ATP biosynthesis 4,5-DOPA a 2,3,4-saturated asd L-tryptophan biosynthesis glu aroC siroheme biosynthesis adhE dehydrogenase: 4-alpha- alpha-L- alpha-L- BR73_RS0117805 (guanine(527)-N(7) isomerase: dehydrogenase: methyltransferase: methyltransferase: acyl-ACP II: fabF hydroxyacyl-[acyl- imidazole leuB UDP-N-acetylmuramoyl- transketolase: dioxygenase fatty acyl-[acp] glutamate 5- glu uracil degradation BR73_RS0104415 glucanotransferase: NADH peroxidase: rhamnosidase: arabinofuranosidase: )-methyltransferase BR73_RS0120940 BR73_RS0110545 cobJ cobM thioesterase: carrier protein] glycerol (2S)-2-isopropyl- L-aspartate 4- chorismate acetaldehyde tripeptide--D-alanyl- BR73_RS0113020 [+ 7 isozymes] extradiol: ygiD kinase: proB I (reductive) [+ 3 isozymes] malQ BR73_RS0103265 BR73_RS0122355 BR73_RS0103585 an insertion 7 RsmG: rsmG [+ 3 isozymes] D-glucono- BR73_RS0103960 3-hydroxyacyl- phosphate 3-oxosuccinate semialdehyde gln γ-L-glutamyl uroporphyrinogen-III ADP acetyl-CoA D- alanine ligase: [+ 2 isozymes] an N - a [protein]-L- precorrin-4 precorrin-5 chorismate sequence IS30 with 527 1,5-lactone 4,5-seco-dopa ACP synthase: L-homoserine 5-phosphate uracil uroporphyrinogen-III bifunctional V-type ATP synthase: urate BR73_RS0118415 methylguanine proline (ω = 0) palmitate 4-hydroxy- β α α integrated transposon dehydratase hisF hisH biosynthesis C-methyltransferase: acetaldehyde- BR73_RS0101895 phosphate thymine degradation -L- an (1,5)- -L- in 16S rRNA tetrahydrodipicolinate glutamate-5- maltopentaose maltose D-glyceraldehyde H O NAD + 4-nitrophenol FabZ: fabZ anthranilate cobA CoA/alcohol BR73_RS0101900 acetyltransferase: pta F6P 2 rhamnopyranose L-arabinan arabinofuranose synthase: purine ribonucleosides degradation UDP-N-acetyl-α-D-muramoyl-L-alanyl- 3-phosphate a trans-2- D-erythro-1- 4-methyl-2- synthase semialdehyde precorrin-1 dehydrogenase: BR73_RS0101905 a 2,3,4-saturated AICAR asp BR73_RS0107250 5,6-dihydrouracil thymine γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine enoyl-[acyl- (imidazol-4- oxopentanoate component I: trpE dehydrogenase: adhE acetyl phosphate fatty acyl-[acp] aspartate kinase: BR73_RS0118605 uroporphyrinogen-III [+ 6 isozymes] carrier protein] yl)-glycerol branched-chain 4-hydroxy- ATP palmitoyl-CoA dihydropyrimidinase: C-methyltransferase: β 967 966 3-phosphate BR73_RS0104040 tetrahydrodipicolinate ethanol adenosine 5,6-dihydrothymine a purine base a -D-glucosyl-N a cytosine a guanine a negatively 5,6- amino acid L-glutamate-5- hydA cobA acetate kinase: D-glucopyranose a maltodextrin F6P FMN NADH H + hydantoin (S)-malate precorrin-8x imidazoleglycerol- aspartate kinase: synthase: anthranilate PRPP lesion in DNA -acylsphingosine in 16S rRNA in 16S rRNA supercoiled DNA dihydrothymine tyr aminotransferase: semialdehyde L-homocysteine biosynthesis BR73_RS0119025 dihydropyrimidinase: NAD-dependent phosphate BR73_RS0108610 BR73_RS0112995 16S rRNA 16S rRNA DNA precorrin-8X L-aspartyl- BR73_RS0123295 (2S,4S)-4- 3-ureidopropanoate precorrin-2 hydA dihydropyrimidinase: dihydropyrimidine fumarate hydratase: tyrosine dehydratase acetate 4-alpha- (cytosine(967)-C(5) (guanine(966)-N(2) topoisomerase III: methylmutase: 4-phosphate anthranilate pyrimidine deoxyribonucleotides formamidopyrimidine- fructose-6- glucosylceramidase: hydA dehydrogenase BR73_RS0102060 decarboxylase HisB: hisB hydroxy-2,3,4,5- bifunctional precorrin- 3-(carbamoylamino)- glucanotransferase: flavin reductase: )-methyltransferase )-methyltransferase BR73_RS0122775 cbiC 3-(imidazol-4- leu tetrahydrodipicolinate phosphoribosyltransferase: trpD L-homoserine dephosphorylation DNA glycosylase: phosphate BR73_RS0106830 subunit PreA: preA MfnA: mfnA Metabolic Regulator 2 dehydrogenase/ 2-methylpropanoate malQ BR73_RS0126135 RsmB: rsmB 2 RsmD: rsmD [+ 3 isozymes] aspartate- (S)-1-pyrroline- BR73_RS0102945 aldolase: fsa 967 an N - Biosynthesis yl)-2-oxopropyl 4-hydroxy- nucleoside triphosphate N-carbamoylglycine a 5-methylcytosine thymine fumarate hydrogenobyrinate p-tyramine semialdehyde 5-carboxylate sirohydrochlorin xanthosine adenosine inosine guanosine methylguanine 966 a relaxed DNA phosphate tetrahydrodipicolinate N-(5-phosphoribosyl)-anthranilate pyrophosphohydrolase: in 16S rRNA dehydrogenase: β ferrochelatase: ppGpp metabolism histidinol-phosphate pyrroline-5- -alanine mazG a [DNA]- D-glyceraldehyde D-glucopyranose a sphingosine in 16S rRNA asd reductase: BR73_RS0118655 dCTP dCMP a 5'-phospho- a modified a maltodextrin maltose dihydroxyacetone FMNH NAD + carboxylate nucleotide- 4-oxo-2-pentenal ceramide 2 transaminase: BR73_RS0107255 (R)-3-amino-2- [DNA] nucleobase 3-phosphate L-aspartate 4- L-tyrosine reductase: O-acetyl-L- pyrimidine/purine pyrimidine/purine pyrimidine/purine pyrimidine/purine 3'-phosphate pppGpp BR73_RS0105800 (S)-2,3,4,5- hydrogen sulfide sirohydrochlorin methylpropanoate semialdehyde biosynthesis I proC homoserine nucleoside nucleoside nucleoside nucleoside histidinol-phosphate tetrahydrodipicolinate 1-(2-carboxyphenylamino)-1- deoxyuridine pyrroline-5- bifunctional precorrin- 5'-triphosphate phosphorylase: phosphorylase: phosphorylase: phosphorylase: transaminase: homoserine chorismate LL-diaminopimelate deoxy-D-ribulose 5-phosphate pyridin-1-ium-3-carboxylate-5- a plant soluble a 2-O-acetylated a long-linear N,N',N''- an N-acyl-D- L-gulono- O-acetylhomoserine 2 dehydrogenase/ nucleotidohydrolase: BR73_RS0118425 BR73_RS0118425 BR73_RS0118425 BR73_RS0118425 a [LarE]-L-cysteine D-glucopyranose α-D-glucopyranose α DHAP oxaloacetate catechol (E)-caffeoyl-CoA methylglyoxal NADH bifunctional (p)ppGpp BR73_RS0119190 dehydrogenase: aminotransferase: L-phenylalanine carboxylate L-cysteine biosynthesis I thiocarboxylate mononucleotide heteroglycan rhamnogalacturonan I -D-glucan triacetylchitotriose glucosamine 1,4-lactone chorismate reductase: aminocarboxypropyltransferase/ sirohydrochlorin BR73_RS0106300 [+ 2 isozymes] [+ 2 isozymes] [+ 2 isozymes] [+ 2 isozymes] synthetase/guanosine- L-histidinol BR73_RS0104030 BR73_RS0122950 biosynthesis I methylglyoxal synthase: citrate/2- type A electron transfer N-acylglucosamine glyoxalase: NAD(+)/ mutase: pheA proC cysteine synthase: ferrochelatase: gluconolactonase: 3',5'-bis(diphosphate) 3'- nucleoside triphosphate α Detoxification 4-alpha- rhamnogalacturonan 4-alpha- beta- BR73_RS0106775 methylcitrate chloramphenicol O- flavoprotein 2-epimerase: BR73_RS0121420 NADH kinase: phosphate L-homoserine prephenate L,L- BR73_RS0124330 BR73_RS0118655 -D-ribose- ATP-dependent BR73_RS0114595 pyrophosphohydrolase: chorismate (1S,2R)-1-C-(indol-3- ser pyrophosphohydrolase: glucanotransferase: acetylesterase: glucanotransferase: hexosaminidase: methylglyoxal synthase: synthase: acetyltransferase: subunit alpha: BR73_RS0103230 [+ 2 isozymes] BR73_RS0120435 diaminopimelate pro 1-phosphate sacrificial sulfur BR73_RS0107860 prephenate chorismate yl)glycerol 3-phosphate serine O- siroheme mazG malQ BR73_RS27255 malQ BR73_RS0111405 BR73_RS0116055 BR73_RS0106770 catA BR73_RS0111460 an N-acyl-D- diaminopimelate dUTP dUMP arsenate transferase LarE: larE 1,2-dihydroxypropane- (R)-lactate L-gulonate NADPH dehydrogenase: mutase: pheA tryptophan L-homocysteine acetyltransferase: cysE arsenate superoxide linezolid resistance methylglyoxal cis,cis-muconate hydrocaffeoyl-CoA mannosamine epimerase: detoxification 1,2,3-tricarboxylate BR73_RS0114030 prephenate synthase: trpB O-acetyl-L-serine III (thioredoxin) detoxification radicals degradation a plant soluble a rhamnogalacturonan a short 1,4- N,N'- N-acetyl-D- GTP ppGpp histidinol BR73_RS0122955 2503 pyridin-1-ium-3,5- maltose 3-(4- BR73_RS0114775 5-hydroxy-CTP 5-hydroxy-CMP D-ribose 5- II (glutaredoxin) adenine a [LarE]-dehydroalanine heteroglycan acetate type I α-D-glucan diacetylchitobiose glucosamine L-glutamate hydroxyphenyl) prephenate phosphate arsenate superoxide in 23S rRNA bisthiocarboxylate mononucleotide histidinol biosynthesis III meso- ser O-acetylhomoserine arsenate pyruvate diaminopimelate dehydratase: indole β-alanine superoxide bifunctional (p)ppGpp dehydrogenase: aminocarboxypropyltransferase/ arsenate pheA biosynthesis III dismutase: Cfr family 23S rRNA hisD 2-oxoglutarate L-alanine diaminopimelate alanine racemization cysteine synthase: reductase ArsC: pyridin-1-ium-3,5- adenine 1518 / β-D-glucopyranose (5R)-5,6-dihydro- adenosyl-cob(III) synthetase/guanosine- 3-phenyl-2- arsenite BR73_RS0117700 (adenine(2503) a [LarE]-L-cysteine D-glucopyranose maltotetraose a β-D-mannoside hesperidin 2,3- a xyloglucan 5-aminolevulinate a cellodextrin citrate 3',5'-bis(diphosphate) 3'- glutamate biosynthesis III decarboxylase: tryptophan BR73_RS0124330 BR73_RS0108940 hydrogen dicarboxylate mononucleotide adenine 1519 in 16S rRNA 1-phosphate 5-(thymidin-7-yl) yrinate a,c-diamide histidinal oxopropanoate synthase: trpB peroxide -C(8))- beta- diaminopropanoate thymidine (in DNA) pyrophosphohydrolase: synthase: BR73_RS0121355 asp [+ 3 isozymes] arsenical arsenite 16S rRNA cobyric acid aconitate gltD gltB tyr BR73_RS0114775 aspartate 1- ala methyltransferase: cfr (adenine(1518)-N(6)/ : spore xyloglucanase: porphobilinogen exoglucanase: BR73_RS0107860 histidinol cys diaminopimelate : alr pump- 4-alpha- alpha-L- diaminopropionate synthase: hydratase decarboxylase: cys arsenical ATP-dependent beta-mannosidase: adenine(1519)-N(6))- pgmB photoproduct lyase: BR73_RS0123940 synthase: hemB BR73_RS28310 dehydrogenase: [+ 2 isozymes] cysteine desulfurase: decarboxylase: driving 2503 glucanotransferase: rhamnosidase: ammonia-lyase: dpaL BR73_RS0105540 AcnA: acnA amino acid racemase: pump-driving 8-methyladenine sacrificial sulfur BR73_RS0114575 BR73_RS0101785 a xyloglucan hisD glu BR73_RS0117630 BR73_RS0125750 BR73_RS0123530 ATPase: 5'-deoxyadenosine met malQ BR73_RS0122355 dimethyltransferase [+ 2 isozymes] β-D-cellobiose trp β-alanine BR73_RS0106280 ATPase: arsA in 23S rRNA transferase LarE: larE β-D-glucose two adjacent adenosylcobyrate oligosaccharide porphobilinogen D-threo-isocitrate GDP [+ 4 isozymes] phe O 6 RsmA: rsmA1518 pyruvate D-ala arsA 2 N -dimethyladenine 6-phosphate thymidines in DNA his ala lys arsenite β-D- a non glycosylated hesperitin-7-O- β-L- /N 6 -dimethyladenine 1519 arsenite a [LarE]-dehydroalanine pyridin-1-ium-3-carboxylate-5- maltose maltotriose mannopyranose sugar acceptor β-D-glucoside rhamnopyranose in 16S rRNA thiocarboxylate mononucleotide Amino Acid Degradation

α a 2'- 55 N-acetyl-β-D- a 6-(N-acetyl- -D-glucosaminyl)- seleno-L- maltotriose a glucan an α-limit dextrin a uridine reduced riboflavin 3-(imidazol- cellotetraose L-arginine degradation acyl-carrier protein a folate deoxyribonucleoside mannosamine 7,8-dihydropterin L-threonine degradation I L-histidine degradation I L-citrulline degradation L-glutamate 1-phosphatidyl-1D-myo-inositol homocysteine in tRNA 5-yl)lactate XIII (reductive ACP S- dihydrofolate reductase: 5'-monophosphate 4-alpha- tRNA N-acylglucosamine L-lactate guanine degradation II 5-methyltetrahydropteroyltriglutamate- flavin reductase: exoglucanase: Stickland reaction) 4-alpha- malonyltransferase: fabD BR73_RS0123305 5'-deoxynucleotidase: glucanotransferase: pseudouridine(55) 2-epimerase: dehydrogenase: deaminase: - homocysteine S-methyltransferase: BR73_RS0126135 BR73_RS28310 thr his L-citrulline N-acetylglucosaminylphosphatidylinositol glucanotransferase: ACP S- dihydrofolate reductase: BR73_RS0125925 malQ synthase TruB: truB BR73_RS0103230 BR73_RS0121300 guaD arg glu BR73_RS0105180 α ornithine deacetylase: BR73_RS0115870 a -limit dextrin 55 threonine histidine malQ malonyltransferase: fabD BR73_RS0100450 a pseudouridine GlcNAc 3-(imidazol- β-D-cellobiose 7,8- carbamoyltransferase: a 2'- with short branches riboflavin ammonia-lyase: ammonia- SeMet a malonyl-[acp] a 7,8-dihydrofolate in tRNA 5-yl)pyruvate dihydrolumazine argF deoxyribonucleoside (2Z)-2-aminobut-BR73_RS0116380 lyase: hutH carbamoyl 6-(α-D-glucosaminyl)-1- L-citrulline urocanate asp acetate a glucan D-glucopyranose 2-enoate phosphate phosphatidyl-1D-myo-inositol carbamate kinase: ornithine urocanate aspartate carbamoyltransferase: hydratase: BR73_RS0119375 an N 6 -L- ammonia-lyase: a pseudouridine 1915 dCMP N-acetyl-D- D-ribulose cytidine BR73_RS0115765 a xyloglucan 37 isoprimeverose N-carbamoylputrescine porphobilinogen a cytosine in DNA 5,6-dihydrouracil ribulose argF carbamoyl- L-serine BR73_RS0124490 threonylcarbamoyladenine mannosamine 5-phosphate 2-iminobutanoate in 23S rRNA 4-imidazolone- phosphate degradation in tRNA 23S rRNA 5'-deoxynucleotidase: N-acylglucosamine ribulose-phosphate uridine kinase: L-ornithine aspartate tRNA DNA cytosine NAD-dependent ribulokinase: 5-propanoate synthase: carB (pseudouridine(1915)- N-carbamoylputrescine hydroxymethylbilane BR73_RS0125925 2-epimerase: 3-epimerase: BR73_RS0112650 ammonia-lyase: xyloglucanase: threonylcarbamoyladenosine alpha- methyltransferase: dihydropyrimidine araB imidazolonepropionase: BR73_RS0123250 ser N(3))-methyltransferase amidase: aguB synthase: hemC BR73_RS0103230 BR73_RS0118365 BR73_RS0118030 BR73_RS0123940 dehydratase: BR73_RS0119775 xylosidase: yicI 2'-deoxycytidine BR73_RS0105635 dehydrogenase CMP 6 RlmH: rlmH N-acetyl-D- BR73_RS0115760 L-serine a cyclic N -L- an N 3 - a 5-methylcytosine subunit PreA: preA D-xylulose L(or D)-ribulose carbamate fumarate putrescine preuroporphyrinogen glucosamine ammonia- threonylcarbamoyladenosine methylpseudouridine 1915 in DNA uracil 5-phosphate 5-phosphate 2-oxobutanoate N-formimino- lyase, XLXG xyloglucan XLFG xyloglucan XXFG xyloglucan 37 in tRNA in 23S rRNA L-glutamate-5- L-glutamate D-glucopyranose α-D-xylopyranose semialdehyde 2-ketobutyrate iron-sulfur- oligosaccharide oligosaccharide oligosaccharide formate- dependent: L-glutamine lyase: pflB CO sdaAB sdaAA degradation I 2 2-aminoprop- L-glutamine 2,5-diamino-6-(5- (R)-4'- a single dUMP N,N'- dTMP uridine carboxynorspermidine uroporphyrinogen-III D-altropyranose cellulose xylan propanoyl-CoA 2-enoate degradation II phospho-D-ribitylamino) phosphopantothenoyl- L-homocysteine stranded DNA diacetylchitobiose (S)-1-pyrroline- gln pyrimidin-4(3H)-one L-cysteine 5'-deoxynucleotidase: beta- 5'-deoxynucleotidase: uridine kinase: alpha- glu bifunctional bifunctional homocysteine uroporphyrinogen-III L-fucose isomerase: endoglucanase: 5-carboxylate phosphate imidazole deoxyribonuclease carboxynorspermidine BR73_RS0125925 hexosaminidase: BR73_RS0125925 BR73_RS0112650 xylosidase: diaminohydroxyphosphoribosylaminopyrimidine phosphopantothenoylcysteine S-methyltransferase/ C-methyltransferase: BR73_RS0112490 propanoyltransferase: gln glycerol IV: BR73_RS0125495 decarboxylase: nspC BR73_RS0118705 pyrroline-5- glutamate deaminase/5-amino-6-(5-phosphoribosylamino) decarboxylase: BR73_RS0124880 methylenetetrahydrofolate cobA BR73_RS0111405 yicI pduL L-asparagine phosphate 2'-deoxyuridine N-acetyl-D- thymidine UMP carboxylate degradation I 2-iminopropanoate synthase: uracil reductase RibD: ribD reductase: BR73_RS0122430 keto-D-psicose a cellodextrin α-D-xylopyranose synthase: 5-amino-6-(5-phospho- 4'-phosphopantetheine a 5'-phosphooligonucleotide norspermidine precorrin-2 glucosamine reductase: propanoyl gltD gltB met proC phosphate hisF hisH D-ribitylamino)uracil asn NADPH- [+ 8 isozymes] pyrroline-5- acetate kinase: dependent glu carboxylate asparaginase: BR73_RS0119025 BR73_RS0115155 pyruvate glutamate reductase: synthase: proC propanoate asp gltA glu pro

L-cystine L-djenkolate phosphonate lanthionine an (aminoalkyl)phosphonate [+ 3 more] an alkylphosphonate arsenite

FliY PhnC ArsA

L-cystine phosphonate L-djenkolate an (aminoalkyl)phosphonate arsenite lanthionine an alkylphosphonate [+ 3 more] This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.