Sea Buckthorn
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HerbalGram 78 • May – July 2008 Kampo: Japanese Herbal Medicine • Ginkgo for Computer Users • Hawthorn for Heart Failure • Herbal Market Report Heart 2006–2007 www.herbalgram.org for • Hawthorn Users Failure – July 2008 Kampo: 78 • May HerbalGram Computer Japanese Herbal Medicine • Ginkgo for Kampo: Japanese Herbal Medicine • Ginkgo for Computer Users • Herbal Market Report 2006–2007 The Journal of the American Botanical Council Number 78 | May – July 2008 US/CAN $6.95 Sea Buckthorn www.herbalgram.org Harvesting Chamomile flowers on the Pharm Farm. PURE HERBS MAKE PURE HERBAL EXTRACTS How we grow and harvest our herbs At Herb Pharm only the highest quality herbs go into our herbal extracts. That’s why we created the “Pharm Farm” – our certified organic farm located near our manufacturing facility in rural southern Oregon. There we grow and process our herbs as nature intended – without the use of genetically modified seeds, synthetic agricultural chemicals, fumigants, or irradiation. For those cultivated herbs we can’t grow ourselves, we procure directly from other organic farmers who we personally know and You’ll find Herb Pharm at trust. This often requires traveling to such remote and exotic loca- fine natural food stores, tions as the Pacific islands of Vanuatu in search of Kava roots, to healthcare clinics, or at a 16,000-foot high Peruvian altiplano sourcing Maca roots, and to the foothills of the Himalayas for Darjeeling Green Tea. www.herb-pharm.com We also harvest our wild herbs in a responsible and sustainable manner – what we’ve termed “Custom Wildcrafted.” Our strict harvesting protocols assure proper botanical identification of each herb species, and their sustainable harvest in their natural wild habitat. We work very hard and go to great lengths to produce herbal products that we feel are purely and simply the best. FFullull SpectrSpectrumum HerbalHerbal Extracts,Extracts, MadeMade WithWith EnvironmentalEnvironmental Responsibility Responsibility Herb Profile Sea Buckthorn Hippophae rhamnoides Family: Elaeagnaceae INTRODUCTION Typically found in the thickets of mountain slopes, standards” established for the seed oil, the fruit oil, high-altitude meadows, river banks, and seashores, sea and for “flavones powder” (powdered extract of fruit buckthorn is a deciduous, hardy, thorny shrub.1,2 It pulp and leaves standardized to isorhamnetin). There produces yellow-green flowers in the spring followed are non-official industry standards established for the by yellow and orange fruits that have a passion fruit juice, juice concentrate, powdered juice (spray-dried flavor when sweetened.1 The dried fruit has a sour and freeze-dried), and wine.11 Sea buckthorn oil, and astringent taste. Native to Asia and Europe, sea extracted from the seeds and/or the fruits, is used exter- buckthorn is widely distributed from China, India, nally in cosmetics as a natural ultraviolet light filter, in Mongolia, and the Russian Federation, to Afghani- skin-regenerating compositions, and as a natural plasti- stan, Kazakhstan, Kyrgyzstan, Pakistan, Tajikistan, cizer and emulsifier.12 In Europe, CO2 extracts of the Turkmenistan, Uzbekistan, and parts of Europe.3 The fruit pulp and of the seeds (oily or semi-solid extracts material of commerce comes primarily from China ©2008 Stevenfoster.com containing CO2-soluble lipohilic components) are and Russia, with increasing production in Kazakh- produced for pharmaceutical products, cosmetics for stan, India, and Germany.4 Pharmacopeial quality sea buckthorn skin care, sunburn, and for essential fatty acid food used in the Chinese system of medicine is collected in autumn and supplements. Sea buckthorn fruit is high in vitamin A and C,1,12 winter when ripe or frozen hard, removed from foreign matter, and protein, fatty acids,13 carotene,14 and vitamin E.15 The fruit is used sun dried or dried after steaming. It must contain a minimum of to make bonbons, marmalades, syrups, fruit-flavored herb teas, 15% ethanol-soluble extractives, minimum 1.5% of total flavonoids liquors, dietary supplements, and medicinal herbal products. (calculated as rutin), and not less than 0.1% of isorhamnetin as deter- Sea buckthorn also has environmental value. Between 1950 and mined by High Performance Liquid Chromatography.5 The material 1985, 200,000 hectares (just over 494,210 acres) of sea buckthorn used in the Tibetan system of medicine is collected from August were planted in China for erosion control and fuel wood produc- to October and processed into a medicinal concentrated decoction tion.16 It is being used to reclaim wasteland and mined areas in form. The pith of the stem is also used medicinally.6 In the European Canada, Germany, Hungary, Romania, and Russia. Anthroposophical system of medicine, the fresh branches with fruit, MODERN RESEARCH the fresh fruits, and the fatty oil obtained from the seeds and/or fruit are used medicinally.7 Both clinical and animal research has shown that sea buckthorn preparations, especially the oil obtained from the seeds or fruit, HISTORY AND CULTURAL SIGNIFICANCE taken internally can treat clinical indicators associated with heart For over a thousand years, preparations made from sea buckthorn disease,17,18,19 and a powdered extract of the fruit and leaf, stan- have been used medicinally in Mongolia, China, and Tibet.2 The dardized to total flavones, was shown to improve heart function first documented benefits of sea buckthorn were recorded in the clas- in a small randomized, double-blind, placebo-controlled trial.20 A sic 8th century CE Tibetan medical text rGyud Bzi (The Four Books randomized controlled trial investigating the effect of an undefined of Pharmacopeia). Young branches and leaves were used in ancient sea buckthorn dry extract granule (Sichuan Pharmaceutical Co. Greece as horse feed, which resulted in weight gain and a healthy LTD) concluded that the extract may be useful for prevention and shine to the horses’ coats, and accounts for the genus name, Hippo- treatment of liver fibrosis.21 A small open-label pilot study inves- phae (shining horse). Sea buckthorn selection and breeding began tigated the treatment of chronic vaginal inflammation with orally in Russia in 1933, and researchers there have investigated active administered capsules containing a mixture of oils extracted from compounds in the plant’s fruits, leaves, and bark since the 1940s.8 sea buckthorn seeds and berries using supercritical CO2 (Omega 7 Russian cosmonauts incorporated the fruit juice into their diet and Sea Buckthorn Oil manufactured by Aromtech Ltd, Finland). Based the fruit pulp oil into a cream to help protect them from solar radia- on improvements seen in the trial, larger clinical trials are justi- tion. An estimated 1.2 million hectares (nearly 3 million acres) of sea fied.22 The same authors carried out a double-blind, placebo-con- buckthorn are found in China, half of which have been cultivated, trolled trial using the same sea buckthorn oil preparation in female with about 150 processing plants that produce over 200 industrial patients with Sjögren’s syndrome (an immunologic disorder charac- and consumer products such as pharmaceuticals and cosmetics.9 Sea terized by the progressive destruction of the exocrine [tear, salivary buckthorn fruit is an official medicine in the Chinese pharmacopeia, and sweat] glands). Results of the trial suggest beneficial effects of indicated for the treatment of cough with profuse expectoration, sea buckthorn oil capsule on the overall condition of the mucous indigestion, stagnancy of food with abdominal pain, amenorrhea due membranes of patients with Sjögren’s syndrome.23 to blood stagnation, and traumatic swelling and bleeding under the Sea buckthorn oil is very stable and has shown promise for exter- skin (eccymosis).10 nal use as a therapeutic skin cream ingredient.24 Numerous trials Various medicinal forms of sea buckthorn are prepared for oral suggest its efficacy in wound and burn healing, skin grafts, and and topical administration in Chinese medicine. In addition to the reducing tissue inflammation.25 Sea buckthorn pulp and seed oil Chinese pharmacopeial standard for the dried fruit (Fructus Hippo- has also been found to improve cases of radiation-induced dermati- phae PPRC), which is used in decoctions, there are other “national tis, wounds, and burns.26 One human clinical trial has shown sea www.herbalgram.org 2008 HerbalGram 78 | 1 SEA BUCKTHORN Continued from page 1 buckthorn oil to be successful in treating skin pigmentation disorders Paris: Lavoisier;1999. and prematurely aging skin, as well as in removing freckles.27 Both 13. Solonenko L.P., Shishkina E.E. Proteins and amino acids in sea buckthorn sea buckthorn pulp oil and seed oil internally have been helpful in fruits. Biologiya, Khimiya I Farmakologiya Oblepikhi. 1983;67-82. Cited alleviating dermatitis in humans.28 (Although the chemistry of the 2 in Li TSC, Beveridge THJ. Sea Buckthorn (Hippophae rhamnoides L.): Production and Utilization. Ottawa: NRC Research Press; 2003. oils differs, they are often combined into one product.) 14. Kostryrko DR. Introduction of useful plants into the Donetsk FUTURE OUTLOOK Botanic Garden of the Ukrainian Academy of Sciences. Introd Akklimat Rast.1990;14:31-34. (from Hortic. Abst. 61: 3368). Cited in Li TSC, Sea buckthorn occurs in sizable stands across the Eurasian conti- Beveridge THJ. Sea Buckthorn (Hippophae rhamnoides L.): Production and nent and there is some concern about its being invasive, although Utilization. Ottawa: NRC Research Press; 2003. there are both natural and conventional agricultural ways of control- 15. Bernath J., Foldesi D., Sea buckthorn (Hippophae rhaminoides L.): ling its spread.2 Conversely, it is rarely observed in the wild in A promising new medicinal and food crop. J Herbs Spices Med Plants. Hungary and is protected there as an endangered species. Some 1992;1:27-35. Cited in Li TSC, Beveridge THJ. Sea Buckthorn (Hippophae experts on sea buckthorn think that this protection needs to be rhamnoides L.): Production and Utilization. Ottawa: NRC Research Press; extended and that considerable research and development needs to 2003.