Twenty-Fourth Annual Report of The
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Department of Biology, Report to the President 2016-2017
Department of Biology Academic year 2016–2017 was exciting and productive for the Department of Biology. The department is considered one of the best biological science departments in the world. Our superb faculty members are leaders in biological research and education. Some of the news regarding our faculty, research, and educational programs is highlighted below. Faculty Count and Departures During AY2017, the Department of Biology had 56 faculty members: 44 full professors, eight associate professors, and four assistant professors. Research homes are distributed among Building 68, the Broad Institute, the Koch Institute for Integrative Cancer Research, the Picower Institute for Learning and Memory, and the Whitehead Institute for Biomedical Research. In addition to 56 primary faculty members, there were six faculty members with secondary appointments in Biology. These joint faculty members provide important connections to other departments, including Brain and Cognitive Sciences, Chemistry, Biological Engineering, and Civil and Environmental Engineering. We are saddened by the loss of Professor Susan Lindquist, who passed away in October 2016. Hidde Ploegh (Whitehead Institute) moved to Children’s Hospital in January 2017. Professor William (Chip) Quinn (Biology/Brain and Cognitive Sciences) retired in July 2016. Faculty Awards Department of Biology faculty members are widely recognized for their contributions to the field. Among our core faculty are three Nobel Laureates, 30 members of the National Academy of Sciences, 28 members of the American Academy of Arts and Sciences, 14 fellows of the American Association for the Advancement of Science, four recipients of the National Science Foundation National Medal of Science, and 15 Howard Hughes Medical Institute (HHMI) investigators. -
Bernard M. Oliver Oral History Interview
http://oac.cdlib.org/findaid/ark:/13030/kt658038wn Online items available Bernard M. Oliver Oral History Interview Daniel Hartwig Stanford University. Libraries.Department of Special Collections and University Archives Stanford, California November 2010 Copyright © 2015 The Board of Trustees of the Leland Stanford Junior University. All rights reserved. Note This encoded finding aid is compliant with Stanford EAD Best Practice Guidelines, Version 1.0. Bernard M. Oliver Oral History SCM0111 1 Interview Overview Call Number: SCM0111 Creator: Oliver, Bernard M., 1916- Title: Bernard M. Oliver oral history interview Dates: 1985-1986 Physical Description: 0.02 Linear feet (1 folder) Summary: Transcript of an interview conducted by Arthur L. Norberg covering Oliver's early life, his education, and work experiences at Bell Laboratories and Hewlett-Packard. Subjects include television research, radar, information theory, organizational climate and objectives at both companies, Hewlett-Packard's associations with Stanford University, and Oliver's association with William Hewlett and David Packard. Language(s): The materials are in English. Repository: Department of Special Collections and University Archives Green Library 557 Escondido Mall Stanford, CA 94305-6064 Email: [email protected] Phone: (650) 725-1022 URL: http://library.stanford.edu/spc Information about Access Reproduction is prohibited. Ownership & Copyright All requests to reproduce, publish, quote from, or otherwise use collection materials must be submitted in writing to the Head of Special Collections and University Archives, Stanford University Libraries, Stanford, California 94304-6064. Consent is given on behalf of Special Collections as the owner of the physical items and is not intended to include or imply permission from the copyright owner. -
ANNUAL REPORT 2019 1 Contents Director’S Letter 1
Whitehead Institute ANNUAL REPORT 2019 1 Contents Director’s Letter 1 Chair’s Letter 3 Members & Fellows 4–5 Science 6 Community 44 Philanthropy 56 2 The Changing Face of Discovery For 37 years, Whitehead Institute has demonstrated an ability to drive scientific discovery and to chart paths into new frontiers of knowledge. Its continuing achievements are due, in substan- tial part, to the unique capacities and dedication of Members who joined the Institute in the 1980s and ‘90s — from Founding Members Gerald Fink, Harvey Lodish, Rudolf Jaenisch, and Robert Weinberg to those who followed, including David Bartel, David Sabatini, Hazel Sive, Terry Orr-Weaver, Richard Young, and me. Those long-serving Members continue to do pioneering science and to be committed teachers and mentors. Yet we have begun an inevitable genera- tional transition: In the last two years, Gerry and Terry have closed their labs, and Harvey will do so this coming year. The exigencies of time mean that, increasingly, Whitehead Institute’s ability to maintain its vigorous scientific leadership depends on our next generation of researchers. As I move toward the conclusion of my term as director, I am particularly proud of the seven current Members and the 14 Whitehead Institute Fellows we recruited during the last 16 years. The newest of those stellar researchers joined us in 2019: Whitehead Institute Member Pulin Li and Whitehead Fellow Kipp Weiskopf. Pulin studies how circuits of interacting genes in individu- al cells enable multicellular functions, such as self-organizing into complex tissues, and her research brilliantly combines approaches from synthetic biology, developmental and stem cell biology, biophysics, and bioengineering to study these multicellular behaviors. -
Ira Sprague Bowen Papers, 1940-1973
http://oac.cdlib.org/findaid/ark:/13030/tf2p300278 No online items Inventory of the Ira Sprague Bowen Papers, 1940-1973 Processed by Ronald S. Brashear; machine-readable finding aid created by Gabriela A. Montoya Manuscripts Department The Huntington Library 1151 Oxford Road San Marino, California 91108 Phone: (626) 405-2203 Fax: (626) 449-5720 Email: [email protected] URL: http://www.huntington.org/huntingtonlibrary.aspx?id=554 © 1998 The Huntington Library. All rights reserved. Observatories of the Carnegie Institution of Washington Collection Inventory of the Ira Sprague 1 Bowen Papers, 1940-1973 Observatories of the Carnegie Institution of Washington Collection Inventory of the Ira Sprague Bowen Paper, 1940-1973 The Huntington Library San Marino, California Contact Information Manuscripts Department The Huntington Library 1151 Oxford Road San Marino, California 91108 Phone: (626) 405-2203 Fax: (626) 449-5720 Email: [email protected] URL: http://www.huntington.org/huntingtonlibrary.aspx?id=554 Processed by: Ronald S. Brashear Encoded by: Gabriela A. Montoya © 1998 The Huntington Library. All rights reserved. Descriptive Summary Title: Ira Sprague Bowen Papers, Date (inclusive): 1940-1973 Creator: Bowen, Ira Sprague Extent: Approximately 29,000 pieces in 88 boxes Repository: The Huntington Library San Marino, California 91108 Language: English. Provenance Placed on permanent deposit in the Huntington Library by the Observatories of the Carnegie Institution of Washington Collection. This was done in 1989 as part of a letter of agreement (dated November 5, 1987) between the Huntington and the Carnegie Observatories. The papers have yet to be officially accessioned. Cataloging of the papers was completed in 1989 prior to their transfer to the Huntington. -
DC Welcomes ASBMB APRIL 28–MAY 2
ASBMB ANNUAL MEETING PULLOUT GUIDE INSIDE April 2007 DC Welcomes ASBMB APRIL 28–MAY 2 American Society for Biochemistry and Molecular Biology Scientists helping scientists… It costs no more to choose the very best for your custom peptides and antibodies… Ac-C T P R Q I pS F N F K-OH ◆ All peptides are made in our laboratories 1461.640 with the most rigorous QC in the industry – pSFNFK-H3PO4 -98 623.245 We sequence every purified -H3PO4 peptide we manufacture! ◆ PhD scientists with over 70 years of 623.0 626.5 combined experience in Chemistry, Mass 293.141 2 Cell Biology and Immunology 1218.599 1169.510 1347.658 536.784 740.405 809.426 1317.591 246.072 499.227 972.531 400 600 800 1000 1200 1400 Mass ◆ Complete antibody protocols and no hidden charges. Phosphospecific antibody experts! ◆ Custom peptides up to 100 AAs in length and at purities up to >98%. Peptides for epitope mapping as low as $4/AA. ◆ Modifications include phosphorylated amino acids, dye-labeling, cyclic peptides, and peptides with stable isotopes. Experience for yourself why research scientists around the world trust 21st Century Biochemicals for their custom peptides and antibodies! Come speak with our scientists at: Experimental Biology, Washington, DC - Booth 130 Apr. 28 – May 2 ARVO, Association for Research in Vision & Ophthalmology, Ft. Lauderdale, FL - Booth 102 May 6 – 9 The American Association of Immunologists, Miami Beach, FL - Booth 427 May 18 – May 22 www.21stcenturybio.com 33 Locke Drive, Marlboro, MA 01752 Made in the P: 508.303.8222 Toll-free: 877.217.8238 U.S.A. -
Claude Elwood Shannon (1916–2001) Solomon W
Claude Elwood Shannon (1916–2001) Solomon W. Golomb, Elwyn Berlekamp, Thomas M. Cover, Robert G. Gallager, James L. Massey, and Andrew J. Viterbi Solomon W. Golomb Done in complete isolation from the community of population geneticists, this work went unpublished While his incredibly inventive mind enriched until it appeared in 1993 in Shannon’s Collected many fields, Claude Shannon’s enduring fame will Papers [5], by which time its results were known surely rest on his 1948 work “A mathematical independently and genetics had become a very theory of communication” [7] and the ongoing rev- different subject. After his Ph.D. thesis Shannon olution in information technology it engendered. wrote nothing further about genetics, and he Shannon, born April 30, 1916, in Petoskey, Michi- expressed skepticism about attempts to expand gan, obtained bachelor’s degrees in both mathe- the domain of information theory beyond the matics and electrical engineering at the University communications area for which he created it. of Michigan in 1936. He then went to M.I.T., and Starting in 1938 Shannon worked at M.I.T. with after spending the summer of 1937 at Bell Tele- Vannevar Bush’s “differential analyzer”, the an- phone Laboratories, he wrote one of the greatest cestral analog computer. After another summer master’s theses ever, published in 1938 as “A sym- (1940) at Bell Labs, he spent the academic year bolic analysis of relay and switching circuits” [8], 1940–41 working under the famous mathemati- in which he showed that the symbolic logic of cian Hermann Weyl at the Institute for Advanced George Boole’s nineteenth century Laws of Thought Study in Princeton, where he also began thinking provided the perfect mathematical model for about recasting communications on a proper switching theory (and indeed for the subsequent mathematical foundation. -
ED093664.Pdf
DOCUMENT RESUME ED 093 664 SE 017 755 TITLE National Science Foundation Annual Report 1973. INSTITUTION National Science Foundation, Washington, D.C. REPORT NO NSF-74-1 PUB DATE 73 NOTE 127p. AVAILABLE FROMSuperintendent of Documents, U.S. Government Printing Office, Washington, D.C. 20402 ($2.35) EDRS PRICE MF-$0.75 HC-$6.60 PLUS POSTAGE DESCRIPTORS *Aunual Reports; Mathematics Education; *Program Descriptions; Research; *Research Projects; Science Education; Sciences; Scientific Research; Teacher Education IDENTIFIERS *National Science Foundation ABSTRACT Statistics on the allotment of funds and descriptions of activities carried out under the auspices of the National Science Foundation (NSF) in 1973 are reported. Details are provided for activities in the categories of:(1) research project support, (2). national and international programs,(3) research applications, (it): science education research and programs, and (5) science resources and policy studies. Among the appendices are a listing of staff, advisory committee, and panel members; details cf organization changes and appointments; a financial report for 1973; a description of patents resulting from NSF-supported activities; a publications list; and a list of national research centers' contractors. (RE) Ii National Science U.S. DEPARTMENT OF HEALTH, ' EDUCATION 8 WELFARE Foundation NATIONAL INSTITUTE OF EDUCATION THIS DOCUMENT HAS BEEN REPRO DUCED EXACTLY AS RECEIVED FROM THE PERSON OR ORGANIZATION ORIGIN MING IT POINTS OF VIEW OR OPINIONS Annual Report 0 STATED DO NOT NECESSARILY REPRE re1 SENT OFFICIAL NATIONAL INSTITUTE OF 90' EDUCATION POSITION OR POLICY. 1973 Letter of Transmittal Washington, D.C. DEAR MR. PRESIDENT: I have the honor to transmit herewith the Annual Report for Fiscal Year 1973 of the National Science Foundation for submission to the Congress as required by the National Science Foundation Act of 1950. -
Harvey Lodish, Phd Professor Biology and Professor of Bioengineering
Harvey Lodish, PhD Professor Biology and Professor of Bioengineering Academic Entrepreneurs, New Technologies, and Building a Biotechnology Ecosystem: A Personal History A leader in the field of molecular and cellular biology, Dr. Harvey F. Lodish has isolated and cloned numerous surface membrane proteins that play a role in blood development, cell signaling, glucose transport, and lipid metabolism. He earned his PhD at the Rockefeller University in 1966. A Founding Member of the Whitehead Institute, Dr. Lodish joined the MIT faculty in 1968 and has been a professor of biology since 1976 and professor of biological engineering since 1999. Dr. Lodish is also the lead author of the widely used textbook Molecular Cell Biology. The book has been translated into 14 languages and the ninth edition appeared in January, 2021. He is a Member of the National Academy of Sciences, a Fellow of the American Association for the Advancement of Science, the American Academy of Arts and Sciences, and the American Academy of Microbiology, and an Associate (Foreign) Member of the European Molecular Biology Organization. He received the 2010 Mentoring Award from the American Society of Hematology, the 2016 American Society for Cell Biology WICB Sandra K. Masur Senior Leadership Mentoring Award, the 2016 Pioneer Award from the Diamond Blackfan Anemia Foundation, and the Metcalf Lifetime Achievement Award from the International Society for Experimental Hematology in 2020. Dr. Lodish is a member of the Board of Trustees of Children’s Hospital, Boston, where he was Chair of the Research Committee of the Board of Trustees. From 2007 - 2014 he was Founding Chair of the Scientific Advisory Board of the Massachusetts Life Sciences Center, the group charged with oversight of the state’s 10- year $1 billion investment in the life sciences. -
Fire Departments of Pathology and Genetics, Stanford University School of Medicine, 300 Pasteur Drive, Room L235, Stanford, CA 94305-5324, USA
GENE SILENCING BY DOUBLE STRANDED RNA Nobel Lecture, December 8, 2006 by Andrew Z. Fire Departments of Pathology and Genetics, Stanford University School of Medicine, 300 Pasteur Drive, Room L235, Stanford, CA 94305-5324, USA. I would like to thank the Nobel Assembly of the Karolinska Institutet for the opportunity to describe some recent work on RNA-triggered gene silencing. First a few disclaimers, however. Telling the full story of gene silencing would be a mammoth enterprise that would take me many years to write and would take you well into the night to read. So we’ll need to abbreviate the story more than a little. Second (and as you will see) we are only in the dawn of our knowledge; so consider the following to be primer... the best we could do as of December 8th, 2006. And third, please understand that the story that I am telling represents the work of several generations of biologists, chemists, and many shades in between. I’m pleased and proud that work from my labo- ratory has contributed to the field, and that this has led to my being chosen as one of the messengers to relay the story in this forum. At the same time, I hope that there will be no confusion of equating our modest contributions with those of the much grander RNAi enterprise. DOUBLE STRANDED RNA AS A BIOLOGICAL ALARM SIGNAL These disclaimers in hand, the story can now start with a biography of the first main character. Double stranded RNA is probably as old (or almost as old) as life on earth. -
Scientific and Related Works of Chen Ning Yang
Scientific and Related Works of Chen Ning Yang [42a] C. N. Yang. Group Theory and the Vibration of Polyatomic Molecules. B.Sc. thesis, National Southwest Associated University (1942). [44a] C. N. Yang. On the Uniqueness of Young's Differentials. Bull. Amer. Math. Soc. 50, 373 (1944). [44b] C. N. Yang. Variation of Interaction Energy with Change of Lattice Constants and Change of Degree of Order. Chinese J. of Phys. 5, 138 (1944). [44c] C. N. Yang. Investigations in the Statistical Theory of Superlattices. M.Sc. thesis, National Tsing Hua University (1944). [45a] C. N. Yang. A Generalization of the Quasi-Chemical Method in the Statistical Theory of Superlattices. J. Chem. Phys. 13, 66 (1945). [45b] C. N. Yang. The Critical Temperature and Discontinuity of Specific Heat of a Superlattice. Chinese J. Phys. 6, 59 (1945). [46a] James Alexander, Geoffrey Chew, Walter Salove, Chen Yang. Translation of the 1933 Pauli article in Handbuch der Physik, volume 14, Part II; Chapter 2, Section B. [47a] C. N. Yang. On Quantized Space-Time. Phys. Rev. 72, 874 (1947). [47b] C. N. Yang and Y. Y. Li. General Theory of the Quasi-Chemical Method in the Statistical Theory of Superlattices. Chinese J. Phys. 7, 59 (1947). [48a] C. N. Yang. On the Angular Distribution in Nuclear Reactions and Coincidence Measurements. Phys. Rev. 74, 764 (1948). 2 [48b] S. K. Allison, H. V. Argo, W. R. Arnold, L. del Rosario, H. A. Wilcox and C. N. Yang. Measurement of Short Range Nuclear Recoils from Disintegrations of the Light Elements. Phys. Rev. 74, 1233 (1948). [48c] C. -
Andrew Viterbi
Andrew Viterbi Interview conducted by Joel West, PhD December 15, 2006 Interview conducted by Joel West, PhD on December 15, 2006 Andrew Viterbi Dr. Andrew J. Viterbi, Ph.D. serves as President of the Viterbi Group LLC and Co- founded it in 2000. Dr. Viterbi co-founded Continuous Computing Corp. and served as its Chief Technology Officer from July 1985 to July 1996. From July 1983 to April 1985, he served as the Senior Vice President and Chief Scientist of M/A-COM Inc. In July 1985, he co-founded QUALCOMM Inc., where Dr. Viterbi served as the Vice Chairman until 2000 and as the Chief Technical Officer until 1996. Under his leadership, QUALCOMM received international recognition for innovative technology in the areas of digital wireless communication systems and products based on Code Division Multiple Access (CDMA) technologies. From October 1968 to April 1985, he held various Executive positions at LINKABIT (M/A-COM LINKABIT after August 1980) and served as the President of the M/A-COM LINKABIT. In 1968, Dr. Viterbi Co-founded LINKABIT Corp., where he served as an Executive Vice President and later as the President in the early 1980's. Dr. Viterbi served as an Advisor at Avalon Ventures. He served as the Vice-Chairman of Continuous Computing Corp. since July 1985. During most of his period of service with LINKABIT, Dr. Viterbi served as the Vice-Chairman and a Director. He has been a Director of Link_A_Media Devices Corporation since August 2010. He serves as a Director of Continuous Computing Corp., Motorola Mobility Holdings, Inc., QUALCOMM Flarion Technologies, Inc., The International Engineering Consortium and Samsung Semiconductor Israel R&D Center Ltd. -
IEEE Information Theory Society Newsletter
IEEE Information Theory Society Newsletter Vol. 63, No. 3, September 2013 Editor: Tara Javidi ISSN 1059-2362 Editorial committee: Ioannis Kontoyiannis, Giuseppe Caire, Meir Feder, Tracey Ho, Joerg Kliewer, Anand Sarwate, Andy Singer, and Sergio Verdú Annual Awards Announced The main annual awards of the • 2013 IEEE Jack Keil Wolf ISIT IEEE Information Theory Society Student Paper Awards were were announced at the 2013 ISIT selected and announced at in Istanbul this summer. the banquet of the Istanbul • The 2014 Claude E. Shannon Symposium. The winners were Award goes to János Körner. the following: He will give the Shannon Lecture at the 2014 ISIT in 1) Mohammad H. Yassaee, for Hawaii. the paper “A Technique for Deriving One-Shot Achiev - • The 2013 Claude E. Shannon ability Results in Network Award was given to Katalin János Körner Daniel Costello Information Theory”, co- Marton in Istanbul. Katalin authored with Mohammad presented her Shannon R. Aref and Amin A. Gohari Lecture on the Wednesday of the Symposium. If you wish to see her slides again or were unable to attend, a copy of 2) Mansoor I. Yousefi, for the paper “Integrable the slides have been posted on our Society website. Communication Channels and the Nonlinear Fourier Transform”, co-authored with Frank. R. Kschischang • The 2013 Aaron D. Wyner Distinguished Service Award goes to Daniel J. Costello. • Several members of our community became IEEE Fellows or received IEEE Medals, please see our web- • The 2013 IT Society Paper Award was given to Shrinivas site for more information: www.itsoc.org/honors Kudekar, Tom Richardson, and Rüdiger Urbanke for their paper “Threshold Saturation via Spatial Coupling: The Claude E.