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Subject Index Subject Index A – labile subunit 3741 – bronchiolitis abdominal – lipase deficiency 522 – wheezing 2181, 2182, 2184 – distention 1825, 1865 acid-base disturbance 298 – cerebellar ataxia 3423 – flatulence 1825 acidemia 298 – chest syndrome (ACS) 2155, 2172, 3011, – malformation 98 acidosis 295, 298, 2491, 2886, 3781 3019 – prenatal diagnosis 98 – distal renal tubular 2843 – confusional migraine 3415, 3582 – mass 3165 – fluid therapy 474 – diarrhea 1755 – migraine 1761, 1172, 1836, 3538 acne 1447 – effects of probiotics 1888 – pain 1757, 1760, 1825, 2764 – antibiotics 1458 – disseminated encephalomyelitis (ADEM) – paracentesis 2058 – azelaic acid 1458 1223, 1224, 2554, 3277, 3410, 3543, 3548 – trauma 672 – benzoyl-peroxide 1458 – multiphasic 3545 – wall anomaly 4006 – comedonal 1453 – pseudorelapsing 3545 – wall defect 3996 – conglobata 1454 – recurrent 3545 abducent nerve (CN VI) 3457 – infantum 1448, 1454 – dysautonomia variant 3480 aberrant airflow 2189 – inversa, see hidradenitis suppurativa – endocarditis 809 abetalipoproteinemia 3429, 3484 – keloidalis 1504 – focal bacterial nephritis 2888 abnormal – miliaris 1448 – gastroenteritis 1847 – atrioventricular conduction 2384 – neonatorum 1429 – feeding 1858 – cilia 2226 – papulo-pustular 1453 – hematogenous osteomyelitis (AHO) 791 – hypothalamic-pituitary development 344 – retinoid 1456 – hemolytic anemia 2977 – red reflex 391 – scarring 1448, 1463 – hemorrhagic leukoencephalomyelitis ABO incompatibility 364 – triad 1505 3411 abortive poliomyelitis 1243 – vulgaris 1453 – hepatic failure 1134, 1140, 1142 absence status epilepticus 3416 acquaporin 2 (AQP2) 290 – hepatitis 1136, 1142, 2076 absolute acquired – inflammatory demyelinating – alcohol 2597 – aplastic anemia 3092 polyradiculoneuropathy 3479 – lymphocyte count (ALC) 1299 – coagulant factor deficiency 3105 – intermittent porphyria (AIP) 562 absorptive hypercalcemia 3623 – facial paralysis 3460 – ischemic stroke 3559, 3564 abusive head trauma 671 – immune deficiency syndrome (AIDS) – kidney injury 2701, 2907, 2908 acanthocytosis 2990 847, 1193, 3418 – liver failure 2095 Acanthosis nigricans 2087 – neutropenia 3081 – lung injury 2141 accelerated – platelet disorders 3074 – lymphoblastic leukemia (ALL) 3169, 3193 – atherosclerosis 2401 acrocyanosis 1427, 2257, 2258 – lymphocytic leukemia (ALL) 67, 68 – idioventricular rhythm (AIVR) 2393 acrodermatitis – motor axonal neuropathy 3479–3481 – junctional rhythm 2392 – enteropathica 710, 1438, 1875 – myelogenous leukemia (AML) 3163 access 2931, 2932 – papulovesicular exanthema 883 – necrotizing encephalopathy 1203, 3410 accessory navicular 3941 acroparesthesia 532 – necrotizing gingivitis (ANG) 1731 accommodative esotropia 3975 ACTH insensitivity 3684, 3686 – necrotizing hemorrhagic acephalgic migraine of childhood 3583 actigraphy 3367 leukoencephalitis 3543 aceruloplasminemia 3433 Actinobacillus actinomycetem comitans 1733 – otitis media (AOM) 863, 865 acetaminophen 2593 actinomyces bovis 1087 – painful event 3008 – hepatotoxicity 2593 actinomycosis 1087, 1735 – pancreatitis 1931 – overdose 2095, 2099 – abdominal 1088 – peritoneal dialysis 2915 acetylcholine 3493 – cervicofacial 1088 – promyelocytic leukemia (APL) 2996 – receptors 3493, 34949 – of the CNS 1089 – pseudomembranous candidiasis (thrush) acetylsalicylic acid 2625 – pelvic 1088 1736 achalasia 1750, 1775 – thoracic 1088 – renal failure 2800, 2907, 2911 Achilles tendon 1603 action tremor 3354 – replacement therapy 2915 – xanthoma 3432 activated partial thromboplastin time 3136 – respiratory distress syndrome (ARDS) Achilles tenotomy 3940 activator protein deficiency 535, 544 1027, 1201, 1214, 2141, 2165, 2231, 2497, achondroplasia 33, 34, 1744, 2221, 2223 acupuncture 3892 2520, 2528, 2916 acid acute – respiratory failure 2519 – ceramidase deficiency 523 – airway obstruction 2195 – rheumatic fever (ARF) 3347 4110 Subject Index – sensory neuropathy of childhood 3480 Aedes allergic – streptococcal gingivostomatitis 1732 – aegypti 1131 – conjunctivitis 1369 – suppurative osteomyelitis 1740 – albopictus 1131 – contact dermatitis 1436, 1467 – toxic encephalopathy 3410 aerobic metabolism 217 – disease 1347 – tubulointerstitial nephritis (ATIN) 2879 aeromonas 1754, 1852 – eosinophilic disease of the esophagus – tumor lysis syndrome (ATLS) 3203 African tick-bite fever 1025 1399 – urticaria 1405, 1406 African trypanosomiasis 3413 – granulomatosis 1691 acyclovir 327, 333, 857, 904, 909 agammaglobulinemia 1268 – ocular disease 3975 acyl-CoA dehydrogenase deficiency 484 aganglionosis 4018 – rhinitis 1361, 3962 acylcarnitine 477 agenesis of the corpus callosum 3282 – allergen avoidance 1365 adalimumab 1910 Ages and Stages Questionnaire (ASQ) 578 – pharmacologic agents 1367 Addison’s disease 1771, 2848, 3683, 3687–3689 agonal breathing 3385 allergy 1347 adefovir 916 agranulocytosis 654 – allergic triad 1348 – dipivoxil 2080 agyria–pachygyria complex 3286 – controller therapy 1355 adenoameloblastoma 1739 Aicardi–Goutieres syndrome 3408 – environmental triggers 1351 adenoid disease 2195 air – hypersensitivity 1347 adenosine 283, 284 – bronchogram 252 – type I 1347 – diphosphate 3072 – embolism 739 – type II 1347 – triphosphate (ATP) 967, 2101, 2225, 2497 – trapping 214, 2189 – type III 1348 adenotonsillar hypertrophy 2221–2224 AIRE mutation 1322 – type IV 1348 adenotonsillectomy 2223 airleak syndrome 206, 229, 251 – management 1354 adenotonsillitis 2195 airway – oral immunotherapy 1358 adenovirus 2539 – and breathing 126 – pollen-induced 1367 – infection 884 – compression 2189, 2192 – reliever therapy 1356 ADH secretion 296 – hyperresponsiveness 1377 – subcutaneous immunotherapy 1356 – hypovolemia-induced 296 – obstruction 2142, 2190, 2191, 2211 – sublingual immunotherapy (SLIT) 1358 adhalinopathy 3526 – resistance 2133, 2189 – testing 1352 adherence to medical regimens 593 – sound 2131 Allgrove syndrome 3686 adiponectin 2087 – suctioning 126 allodynia 609, 1625 adiposity 718 akathisia 3346 allogeneic HSCT 3180, 3181 adipsic disorder 3732 AKI 2921, 2922 allograft adolescence akinetic-mutism 3380 – patch arterioplasty 2376 – active military service 3898 ALAD (5-aminolevulinic acid dehydratase) – vasculopathy 2472 – gynecology 3839 deficiency porphyria 561 alloimmune hemolytic disease 425 – health care 3885 ALADIN syndrome 3686 allopurinol 76, 2873 – male health 3855 Alagille syndrome 1994, 1995, 2263, 2333, alopecia 1490, 1631 – normal development 3821 2335, 3233 – areata 1499, 1512 – nutrient needs 3830 alanine aminotransferase (ALT) 1963, 2593 – cicatricial 1503 – nutrition and weight control 3829 Albers-Scho¨nberg disease 1744 – nonscarring 1491 – psychosocial development 3823 albinism 1523 – scarring 1490 – sexuality development 3825 Albright’s hereditary osteodystrophy 3617 – totalis 1500 adolescent iron deficiency anemia 2966 albumin 1974, 3046 – triangularis 1491 adrenal albuminuria 2714 – universalis 1501 – disorder 3675 alcohol 2597, 3822, 3871 Alpers–Huttenlocher syndrome 2104, 3407, – hypoplasia congenita 3685 – dehydrogenase 2598 3408 – incidentaloma 3710 – toxicity 2599 alpha-1-antitrypsin 1891, 1894 – insufficiency 263, 343, 3683, 3687 Alder-Reilly anomaly 3083 – deficiency 2003 – steroidogenesis 3665 aldolase – diagnosis of liver disease 2004 adrenalectomy 3668 – B gene 2021 alpha-fetoprotein 2794 adrenocortical – deficiency 2983 alphavirus 1259 – carcinoma 3700, 3708 aldosterone 1865, 1867, 2654, 3675–3681, 3685, Alport syndrome 2708, 2709, 2757, – steroidogenesis 3676 3688, 3690, 3691, 3693–3697, 3699, 3700 2806, 2942 adrenocorticotropic hormone (ACTH) 493, – deficiency 341, 2848 Alstrom syndrome 772 1624, 2578, 3609, 3806 – receptor 2840 altered potassium metabolism 2663 adrenogenital syndrome 2848 Alexander Disease 3407 alveolar echinococcosis 1091, 1094 adrenoleukodystrophy 345, 3414, 3550, alkali 1778 Alzheimer’s disease 62 3684–3687 alkaline phosphatase 1973, 3613 amantadine 914 adrenomyeloneuropathy 3434 alkalosis 298, 1865 amaurosis fugax 112 advanced sleep phase syndrome (ASPS) 3370 alkylating agent 2803, 3169 ambiguous genitals 3649, 3698 Adverse Childhood Experiences (ACE) allele 13 amblyopia 598, 3973 study 678 allergen immunotherapy 1369, 1386 amebiasis 1075 Subject Index 4111 amebic Andersen–Tawil syndrome 3532, 3533 antibiotic – colitis 1075 andmyringotomy 869 – lock therapy (ALT) 836 – dysentery 1076 androgen 3675–3677, 3679, 3680, 3682, – medication 4088 – liver abscess 1076 3690–3696, 3698 antibody ameboma 1076 – excess syndrome 3848 – against b2 glycoprotein I 1641 ameloblastic – insensitivity 3660, 3847 – deficiency 1329 – fibroma 1739 – resistance 3660 antibody-dependent cell-mediated cytotoxicity – odontoma 1739 androstenedione 341 (ADCC) 1269 ameloblastoma 1739 anemia 359, 399, 962, 965, 2949–2955 anticardiolipin antibodies 1641, 1645 amenorrhea 3847 – hypoplastic 360 anticholinergics 1368 American dog tick 1025 – iron deficiency 361, 2965 anticholinesterase 2611 American Heart Association (AHA) 810 – of prematurity 360 anticoagulant protein 3131 American leishmaniasis 1101 anencephaly 95, 3281 anticoagulation 2062, 3101 amidorone 284 anetoderma of prematurity 1434 – therapy 1646 amino acid 737 aneupliody 45, 397 anticonvulsants 1413 – disorder 463 angel’s kiss 141, 1555 antidepressant 2601 – metabolism disorder 451 Angelman syndrome 22, 66, 615, 3425 antidiuretic hormone (ADH) 2515 amino acidemia 492 angioedema 78, 1409, 1410 – cyclic 2601 aminoaciduria 2865, 3268 angioplasty 1696 antidote 2590 aminoglycoside 79, 889, 896 angiotensin antidromic AV reciprocating tachycardia 282 aminolevulinic acid (ALA) 562 – converting
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