TAX1BP1 Rabbit Polyclonal Antibody – TA323328 | Origene

OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for TA323328

TAX1BP1 Rabbit Polyclonal Antibody Product data:

Product Type: Primary Antibodies Applications: IHC Recommended Dilution: ELISA: 1:3000-10000, IHC: 1:100-300 Reactivity: Human, Mouse, Rat Host: Rabbit Isotype: IgG Clonality: Polyclonal Immunogen: Fusion protein corresponding to a region derived from 180-420 amino acids of human Tax1 (human T-cell leukemia virus type I) binding protein 1 Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol Concentration: lot specific Purification: Antigen affinity purification Conjugation: Unconjugated Storage: Store at -20°C as received. Stability: Stable for 12 months from date of receipt. Gene Name: Tax1 binding protein 1 Database Link: NP_006015 Entrez Gene 52440 MouseEntrez Gene 246244 RatEntrez Gene 8887 Human Q86VP1 Background: This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3; and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[ Synonyms: CALCOCO3; T6BP; TXBP151 Protein Families: Druggable Genome

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 2 TAX1BP1 Rabbit Polyclonal Antibody – TA323328

Product images:

Predicted cell location: Cytoplasm, Nucleus. Positive control: Human colon and esophagus cancer tissue. Recommended dilution: 1/100-300 The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using TAX1BP1 antibody at dilution 1/60, on the right is treated with the fusion protein. (Original magnification:x 200)

Predicted cell location: Cytoplasm, Nucleus. Positive control: Human colon and esophagus cancer tissue. Recommended dilution: 1/100-300 The image on the left is immunohistochemistry of paraffin-embedded human esophagus cancer tissue using TAX1BP1 antibody at dilution 1/60, on the right is treated with the fusion protein. (Original magnification:x200)