International Journal of Environmental Research and Public Health Brief Report Brief Report on Double-Chamber Syringes Patents and Implications for Infusion Therapy Safety and Efficiency Liliana B. Sousa 1,* , Paulo Santos-Costa 1,2 , Inês A. Marques 3, Arménio Cruz 1 , Anabela Salgueiro-Oliveira 1 and Pedro Parreira 1 1 Health Sciences Research Unit: Nursing (UICISA:E), Nursing School of Coimbra (ESEnfC), 3046-851 Coimbra, Portugal;
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[email protected] (P.P.) 2 Instituto de Ciências da Saúde, Universidade Católica Portuguesa, 4169-005 Porto, Portugal 3 Biophysics Institute, Coimbra Institute for Clinical and Biomedical Research (iCBR) Area of CIMAGO, Faculty of Medicine, CNC.IBILI, Faculty of Medicine, University of Coimbra, Polo das Ciências da Saúde Azinhaga de Santa Comba, 3000-354 Coimbra, Portugal;
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[email protected] Received: 13 October 2020; Accepted: 5 November 2020; Published: 6 November 2020 Abstract: This review aimed to map the existing patents of double-chamber syringes that can be used for intravenous drug administration and catheter flush. A search was conducted in the Google patents database for records published prior to 28 October 2020, using several search terms related to double-chamber syringes (DCS). Study eligibility and data extraction were performed by two independent reviewers. Of the initial 26,110 patents found, 24 were included in this review. The 24 DCS that were found display two or more independent chambers that allow for the administration of multiple solutions. While some of the DCS have designated one of the chambers as the flushing chamber, most patents only allow for the sequential use of the flushing chamber after intravenous drug administration.