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Supplementary Table S1 . 939 Differentially Expressed Genes in Invasive Cells with EGFR Over-Expression and P53 Mutation

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Supplementary Table S1 . 939 Differentially Expressed Genes in Invasive Cells with EGFR Over-Expression and P53 Mutation Supplementary Table S1 . 939 Differentially Expressed Genes in Invasive Cells with EGFR Over-expression and P53 Mutation AffyID Gene Fold Chromosomal_Location Gene_Title Change* 210809_s_at POSTN 6.54 chr13q13.3 periostin, osteoblast specific factor 202237_at NNMT 5.76 chr11q23.1 nicotinamide N-methyltransferase 226237_at COL8A1 5.43 --- --- 58780_s_at FLJ10357 5.41 chr14q11.2 hypothetical protein FLJ10357 201109_s_at THBS1 5.11 chr15q15 thrombospondin 1 213905_x_at BGN 5.07 chrXq28 biglycan 229125_at LOC163782 4.79 chr1p31.3 KN motif and ankyrin repeat domains 4 209278_s_at TFPI2 4.64 chr7q22 tissue factor pathway inhibitor 2 202766_s_at FBN1 4.63 chr15q21.1 fibrillin 1 204955_at SRPX 4.61 chrXp21.1 sushi-repeat-containing protein, X-linked 204083_s_at TPM2 4.44 chr9p13.2-p13.1 tropomyosin 2 (beta) 212473_s_at MICAL2 4.34 chr11p15.3 microtubule associated monoxygenase, calponin and LIM domain containing 2 211964_at COL4A2 4.28 chr13q34 collagen, type IV, alpha 2 201261_x_at BGN 4.28 chrXq28 biglycan 216250_s_at LPXN 4.17 chr11q12.1 leupaxin 209651_at TGFB1I1 4.15 chr16p11.2 transforming growth factor beta 1 induced transcript 1 226905_at MGC45871 4.15 chr17p13 family with sequence similarity 101, member B 201431_s_at DPYSL3 4.14 chr5q32 dihydropyrimidinase-like 3 200974_at ACTA2 4.10 chr10q23.3 actin, alpha 2, smooth muscle, aorta 226876_at MGC45871 4.09 chr17p13 family with sequence similarity 101, member B 206300_s_at PTHLH 4.01 chr12p12.1-p11.2 parathyroid hormone-like hormone 227566_at HNT 3.98 chr11q25 neurotrimin 201110_s_at THBS1 3.94 chr15q15 thrombospondin 1 210511_s_at INHBA 3.93 chr7p15-p13 inhibin, beta A 225681_at CTHRC1 3.84 chr8q22.3 collagen triple helix repeat containing 1 44783_s_at HEY1 3.84 chr8q21 hairy/enhancer-of-split related with YRPW motif 1 202686_s_at AXL 3.80 chr19q13.1 AXL receptor tyrosine kinase 206247_at MICB 3.78 chr6p21.3 MHC class I polypeptide-related sequence B 227059_at GPC6 3.73 chr13q32 glypican 6 201162_at IGFBP7 3.72 chr4q12 insulin-like growth factor binding protein 7 212667_at SPARC 3.72 chr5q31.3-q32 secreted protein, acidic, cysteine-rich (osteonectin) 231766_s_at COL12A1 3.67 chr6q12-q13 collagen, type XII, alpha 1 212472_at MICAL2 3.63 chr11p15.3 microtubule associated monoxygenase, calponin and LIM domain containing 2 201108_s_at THBS1 3.61 chr15q15 thrombospondin 1 213869_x_at THY1 3.60 chr11q22.3-q23 Thy-1 cell surface antigen 203925_at GCLM 3.58 chr1p22.1 glutamate-cysteine ligase, modifier subunit 212609_s_at SDCCAG8 3.58 chr1q43-q44 Clones 23920 and 23921 mRNA sequence 1556773_at PTHLH 3.53 --- --- 221059_s_at CHST6 3.52 chr16q24.1 coactosin-like 1 (Dictyostelium) 211980_at COL4A1 3.51 chr13q34 collagen, type IV, alpha 1 201389_at ITGA5 3.50 chr12q11-q13 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 202760_s_at AKAP2 3.47 chr9q31-q33 PALM2-AKAP2 readthrough transcript 229218_at COL1A2 3.47 chr7q22.1 collagen, type I, alpha 2 212013_at D2S448 3.46 chr2p25 peroxidasin homolog (Drosophila) 201645_at TNC 3.44 chr9q33 tenascin C 210355_at PTHLH 3.43 chr12p12.1-p11.2 parathyroid hormone-like hormone 203562_at FEZ1 3.37 chr11q24.2 fasciculation and elongation protein zeta 1 (zygin I) 206580_s_at EFEMP2 3.36 chr11q13.1 EGF-containing fibulin-like extracellular matrix protein 2 201666_at TIMP1 3.34 chrXp11.3-p11.23 TIMP metallopeptidase inhibitor 1 213010_at PRKCDBP 3.31 chr11p15.4 protein kinase C, delta binding protein 228033_at E2F7 3.31 chr12q21.2 E2F transcription factor 7 224911_s_at DCBLD2 3.31 chr3q12.1|3 discoidin, CUB and LCCL domain containing 2 204115_at GNG11 3.30 chr7q21 guanine nucleotide binding protein (G protein), gamma 11 202759_s_at AKAP2 chr9q31-q33 A kinase (PRKA) anchor protein 2 /// paralemmin 2 /// PALM2-AKAP2 readthrough transcript 3.30 226694_at AKAP2 chr9q31-q33 A kinase (PRKA) anchor protein 2 /// paralemmin 2 /// PALM2-AKAP2 readthrough transcript 3.30 204464_s_at EDNRA 3.30 chr4q31.23 endothelin receptor type A 225664_at COL12A1 3.29 chr6q12-q13 collagen, type XII, alpha 1 209270_at LAMB3 3.27 chr1q32 laminin, beta 3 212233_at MAP1B 3.26 chr5q13 microtubule-associated protein 1B 225524_at ANTXR2 3.24 chr4q21.21 anthrax toxin receptor 2 209210_s_at PLEKHC1 3.24 chr14q22.2 fermitin family homolog 2 (Drosophila) 212624_s_at CHN1 3.23 chr2q31.1 chimerin (chimaerin) 1 209277_at TFPI2 3.22 chr7q22 tissue factor pathway inhibitor 2 206467_x_at TNFRSF6B chr20q13.3 regulator of telomere elongation helicase 1 /// tumor necrosis factor receptor superfamily, member 3.22 6b, decoy 217853_at TENS1 3.21 chr7p12.3 tensin 3 214085_x_at GLIPR1 3.19 chr12q21.2 GLI pathogenesis-related 1 207826_s_at ID3 3.18 chr1p36.13-p36.12 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 212489_at COL5A1 3.17 chr9q34.2-q34.3 collagen, type V, alpha 1 208962_s_at FADS1 3.16 chr11q12.2-q13.1 fatty acid desaturase 1 202998_s_at LOXL2 3.15 chr8p21.3 /// chr8p21.3-p21.2 ectonucleoside triphosphate diphosphohydrolase 4 /// lysyl oxidase-like 2 202270_at GBP1 3.10 chr1p22.2 guanylate binding protein 1, interferon-inducible, 67kDa 225673_at MYADM 3.10 chr19q13.41 myeloid-associated differentiation marker 230175_s_at ESDN 3.08 --- --- 201105_at LGALS1 3.06 chr22q13.1 lectin, galactoside-binding, soluble, 1 202870_s_at CDC20 3.05 chr1p34.1 cell division cycle 20 homolog (S. cerevisiae) 227534_at C9orf21 3.03 chr9q22.32 chromosome 9 open reading frame 21 52255_s_at COL5A3 3.02 chr19p13.2 collagen, type V, alpha 3 238447_at RBMS3 3.02 chr3p24-p23 RNA binding motif, single stranded interacting protein 214104_at GPR161 3.00 chr1q24.2 G protein-coupled receptor 161 204030_s_at SCHIP1 3.00 chr3q25.33 schwannomin interacting protein 1 211756_at PTHLH 2.99 chr12p12.1-p11.2 parathyroid hormone-like hormone 65718_at GPR124 2.98 chr8p12 G protein-coupled receptor 124 203217_s_at SIAT9 2.97 chr2p11.2 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 223307_at CDCA3 2.96 chr12p13 cell division cycle associated 3 205120_s_at SGCB 2.94 chr4q12 sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 221916_at NEFL 2.93 chr8p21 neurofilament, light polypeptide 212464_s_at FN1 2.93 chr2q34 fibronectin 1 218651_s_at FLJ11196 2.90 chr15q23 La ribonucleoprotein domain family, member 6 204682_at LTBP2 2.89 chr14q24 latent transforming growth factor beta binding protein 2 219117_s_at FKBP11 2.89 chr12q13.12 FK506 binding protein 11, 19 kDa 1555630_a_at RAB34 2.88 chr17q11.2 RAB34, member RAS oncogene family 37408_at MRC2 2.87 chr17q23.2 mannose receptor, C type 2 210987_x_at TPM1 2.87 chr15q22.1 tropomyosin 1 (alpha) 219257_s_at SPHK1 2.86 chr17q25.2 sphingosine kinase 1 228573_at ANTXR2 2.84 --- --- 203060_s_at PAPSS2 2.82 chr10q23-q24 3'-phosphoadenosine 5'-phosphosulfate synthase 2 212022_s_at MKI67 2.81 chr10q25-qter antigen identified by monoclonal antibody Ki-67 227279_at MGC15737 2.80 chrXq22.2 transcription elongation factor A (SII)-like 3 201163_s_at IGFBP7 2.80 chr4q12 insulin-like growth factor binding protein 7 211340_s_at MCAM 2.79 chr11q23.3 melanoma cell adhesion molecule 213943_at TWIST1 2.79 chr7p21.2 twist homolog 1 (Drosophila) 202267_at LAMC2 2.76 chr1q25-q31 laminin, gamma 2 224759_s_at MGC17943 2.76 chr12q23.3 chromosome 12 open reading frame 23 218638_s_at SPON2 2.74 chr4p16.3 spondin 2, extracellular matrix protein 209946_at VEGFC 2.73 chr4q34.1-q34.3 vascular endothelial growth factor C 212607_at AKT3 2.72 chr1q43-q44 v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) 221805_at NEFL 2.72 chr8p21 neurofilament, light polypeptide 208637_x_at ACTN1 2.72 chr14q24.1-q24.2|14q24|14q22-q24 actinin, alpha 1 222108_at AMIGO2 2.71 chr12q13.11 adhesion molecule with Ig-like domain 2 211160_x_at ACTN1 2.71 chr14q24.1-q24.2|14q24|14q22-q24 actinin, alpha 1 213262_at SACS 2.70 chr13q12 spastic ataxia of Charlevoix-Saguenay (sacsin) 218656_s_at LHFP 2.70 chr13q12 lipoma HMGIC fusion partner 200762_at DPYSL2 2.69 chr8p22-p21 dihydropyrimidinase-like 2 208851_s_at THY1 2.69 chr11q22.3-q23 Thy-1 cell surface antigen 224833_at ETS1 2.69 chr11q23.3 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) 205534_at PCDH7 2.66 chr4p15 protocadherin 7 224252_s_at FXYD5 2.66 chr19q12-q13.1 FXYD domain containing ion transport regulator 5 229404_at TWIST2 2.65 chr2q37.3 twist homolog 2 (Drosophila) 227211_at PHF19 2.64 chr9q33.2 PHD finger protein 19 209335_at DCN 2.64 chr12q21.33 decorin 223378_at GLIS2 2.62 chr16p13.3 GLIS family zinc finger 2 204466_s_at SNCA 2.61 chr4q21 synuclein, alpha (non A4 component of amyloid precursor) 201843_s_at EFEMP1 2.61 chr2p16 EGF-containing fibulin-like extracellular matrix protein 1 216442_x_at FN1 2.59 chr2q34 fibronectin 1 208963_x_at FADS1 2.58 chr11q12.2-q13.1 fatty acid desaturase 1 208964_s_at FADS1 2.58 chr11q12.2-q13.1 fatty acid desaturase 1 204279_at PSMB9 chr6p21.3 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) 2.58 210495_x_at FN1 2.57 chr2q34 fibronectin 1 212110_at SLC39A14 2.57 chr8p21.3 solute carrier family 39 (zinc transporter), member 14 213069_at HEG 2.57 chr3q21.2 HEG homolog 1 (zebrafish) 219305_x_at FBXO2 2.56 chr1p36.22 F-box protein 2 227759_at PCSK9 2.56 chr1p32.3 proprotein convertase subtilisin/kexin type 9 202555_s_at MYLK 2.56 chr3q21 myosin light chain kinase 218980_at FHOD3 2.56 chr18q12 formin homology 2 domain containing 3 218368_s_at TNFRSF12A 2.55 chr16p13.3 tumor necrosis factor receptor superfamily, member 12A 214710_s_at CCNB1 2.55 chr5q12 cyclin B1 224710_at RAB34 2.54 chr17q11.2 RAB34, member RAS oncogene family 202206_at
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