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Acids and Aldehydes Acids and Aldehydes An Acid is an organic compound with acidic properties, mostly produced in the plants. Some organic acids are with carboxyl group -COOH, group -SO2OH. Other groups can also confer acidity, usually weakly: the thiol group -SH, the enol group, and the phenol group. Organice acids are commonly used for acidulant, antioxidant, flavoring agent, and some possess antibacterial activities. An aldehyde is an organic compound containing a functional group with the structure -CHO, consisting of a carbonyl center (a carbon double-bonded to oxygen) with the carbon atom also bonded to hydrogen and to an R group, which is any generic alkyl or side chain. Many aldehydes are found in essential oils and often contribute to their favorable odors, e.g. cinnamaldehyde, cilantro, and vanillin. Possibly because of the high reactivity of the formyl group, aldehydes are not common in several of the natural building blocks: amino acids, nucleic acids, lipids. Most sugars, however, are derivatives of aldehydes. These aldoses exist as hemiacetals, a sort of masked form of the parent aldehyde. For example, in aqueous solution only a tiny fraction of glucose exists as the aldehyde. www.MedChemExpress.com 1 Acids and Aldehydes Inhibitors & Modulators (+)-Usnic acid (-)-Hydroxycitric acid Cat. No.: HY-N0656A (Garcinia acid) Cat. No.: HY-16007 (+)-Usnic acid is isolated from isolated from (-)-Hydroxycitric acid (Garcinia acid) is the lichens, binds at the ATP-binding pocket of principal acid of fruit rinds of Garcinia mTOR, and inhibits mTORC1/2 activity. cambogia. (-)-Hydroxycitric acid is a potent (+)-Usnic acid inhibits the phosphorylation of and competitive inhibitor of ATP citrate lyase. mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer activity. Purity: >99.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 100 mg Size: 1 mg, 5 mg (-)-Hydroxycitric acid lactone (2-Aminoethyl)phosphonic acid (Garcinia lactone) Cat. No.: HY-N7347 Cat. No.: HY-W006371 (-)-Hydroxycitric acid lactone (Garcinia lactone) (2-Aminoethyl)phosphonic acid is an endogenous is an anti-obesity agent and a popular weight loss metabolite. food supplement. (-)-Hydroxycitric acid lactone is a potent inhibitor of ATP-citrate lyase. Purity: >98% Purity: >97.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 100 mg (2R)-2-Hydroxypropanoate sodium (9Z,​11E)​-​Prodlure ((9Z,11E)-Tetradecadien-1-yl acetate; Cat. No.: HY-111095B Ferodin SL; Litlure A) Cat. No.: HY-101735 (2R)-2-Hydroxypropanoate sodium is an endogenous (9Z,​11E)​-​Prodlure ((9Z,11E)-Tetradecadien-1-yl metabolite. acetate) is the main component of the sex pheromone of female Spodoptera littoralis. Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 10 mg, 50 mg (E)-2-Methyl-2-pentenoic acid (E)-m-Coumaric acid Cat. No.: HY-W010533 Cat. No.: HY-N7127 (E)-2-Methyl-2-pentenoic acid is the component can (E)-m-Coumaric acid (3-Hydroxycinnamic acid) is an be used to synthesize the cytotoxic natural aromatic acid that highly abundant in food. product Lactimidomycin. (E)-m-Coumaric acid (3-Hydroxycinnamic acid) is an antioxidant. Purity: >98% Purity: 99.98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 100 mg (E)-Oct-2-enoic acid (E/Z)-Ginkgolic acid C17:2 Cat. No.: HY-W046906 Cat. No.: HY-N7961 (E)-Oct-2-enoic acid is an endogenous metabolite. (E/Z)-Ginkgolic acid C17:2, isolated from Ginkgo biloba, can bind with human dihydroorotate dehydrogenase (DHODH) tightly. Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg 2 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected] (R)-3-Hydroxybutanoic acid (R)-3-Hydroxyisobutyric acid Cat. No.: HY-W051723 Cat. No.: HY-113108 (R)-3-Hydroxybutanoic acid is a metabolite, and (R)-3-Hydroxyisobutyric acid is an intermediate in converted from acetoacetic acid catalyzed by the pathways of l-valine and thymine and plays an 3-hydroxybutyrate dehydrogenase. important role in the diagnosis of the very rare inherited metabolic diseases 3-hydroxyisobutyric aciduria and methylmalonic semialdehyde dehydrogenase deficiency. Purity: >97.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 50 mg Size: 1 mg, 5 mg (R)-5-Oxopyrrolidine-2-carboxylic acid (R)-Leucic acid Cat. No.: HY-W002304 (D-α-Hydroxyisocaproic acid) Cat. No.: HY-30216 (R)-5-Oxopyrrolidine-2-carboxylic acid is an (R)-Leucic acid is an amino acid metabolite. endogenous metabolite. Purity: >98.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 100 mg Size: 100 mg (R)-Ornithine hydrochloride (R)-pyrrolidine-2-carboxylic acid ((+)-(R)-Proline; Cat. No.: HY-34516 (R)-(+)-Proline; (R)-2-Carboxypyrrolidine; (R)-Proline) Cat. No.: HY-75087 (R)-Ornithine hydrochloride is an endogenous (R)-pyrrolidine-2-carboxylic acid is an endogenous metabolite. metabolite. Purity: >98.0% Purity: >97.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 500 mg, 1 g Size: 10 mM × 1 mL, 500 mg, 1 g (R)-Serine (S)-2-acetamido-4-amino-4-oxobutanoic acid Cat. No.: HY-100808 Cat. No.: HY-W016798 (R)-Serine, an endogenous amino acid involved in (S)-2-acetamido-4-amino-4-oxobutanoic acid is an glia-synapse interactions that has unique endogenous metabolite. neurotransmitter characteristics, is a potent co-agonist at the NMDA glutamate receptor. Purity: >98.0% Purity: >98% Clinical Data: Launched Clinical Data: No Development Reported Size: 10 mM × 1 mL, 500 mg, 1 g, 5 g Size: 1 mg, 5 mg (S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid (S)-2-Hydroxy-3-phenylpropanoic acid dihydrate Cat. No.: HY-W008437 Cat. No.: HY-30220 (S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoi (S)-2-Hydroxy-3-phenylpropanoic acid is a product c acid dihydrate is an endogenous metabolite. of phenylalanine catabolism. An elevated level of phenyllactic acid is found in body fluids of patients with or phenylketonuria. Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 100 mg www.MedChemExpress.com 3 (S)-2-Hydroxysuccinic acid (S)-3,4-Dihydroxybutyric acid Cat. No.: HY-Y1069 Cat. No.: HY-113304 (S)-2-Hydroxysuccinic acid is a dicarboxylic acid (S)-3,4-Dihydroxybutyric acid is a normal human in naturally occurring form, contributes to the urinary metabolite that is excreted in increased pleasantly sour taste of fruits and is used as a concentration in patients with succinic food additive. semialdehyde dehydrogenase (SSADH) deficiency. Purity: >97.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 100 mg Size: 1 mg, 5 mg (S)-3-Hydroxy-2-(Phosphonooxy)Propanoic Acid (S)-3-Hydroxybutanoic acid ((S)-β-Hydroxybutanoic acid; Cat. No.: HY-128736 L-(+)-3-Hydroxybutyric acid; L-β-Hydroxybutyric acid) Cat. No.: HY-W050031 (S)-3-Hydroxy-2-(Phosphonooxy)Propanoic Acid is an (S)-3-Hydroxybutanoic acid is a normal human endogenous metabolite. metabolite, that has been found elevated in geriatric patients remitting from depression. Purity: >98% Purity: >97.0% Clinical Data: No Development Reported Clinical Data: Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 50 mg (S)-3-Hydroxyisobutyric acid (S)-b-aminoisobutyric acid Cat. No.: HY-113126 Cat. No.: HY-113380 (S)-3-Hydroxyisobutyric acid is an important (S)-b-aminoisobutyric acid is a non-protein amino interorgan metabolite, an intermediate in the acid originating from the catabolism of thymine pathways of l-valine and thymine and a good and valine. gluconeogenic substrate. Purity: >92.0% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg, 100 mg (S)-Glutamic acid (S)-Indoximod ((+)-L-Glutamic acid) Cat. No.: HY-14608 (1-Methyl-L-tryptophan; (S)-NLG-8189) Cat. No.: HY-N0707 (S)-Glutamic acid acts as an excitatory (S)-Indoximod (1-Methyl-L-tryptophan) is an transmitter and an agonist at all subtypes of inhibitor of indoleamine 2,3-dioxygenase (IDO). glutamate receptors (metabotropic, kainate, NMDA, (S)-Indoximod can be used for the research of and AMPA). (S)-Glutamic acid shows a direct cancer. activating effect on the release of DA from dopaminergic terminals. Purity: >97.0% Purity: 99.03% Clinical Data: Launched Clinical Data: No Development Reported Size: 10 mM × 1 mL, 100 mg, 500 mg Size: 10 mM × 1 mL, 100 mg (Z)-2-Decenoic acid (Z)-4-Amino-4-oxobut-2-enoic acid (cis-2-Decenoic acid) Cat. No.: HY-13212 Cat. No.: HY-128750 (Z)-2-decenoic acid (cis-2-Decenoic acid) is an (Z)-4-Amino-4-oxobut-2-enoic acid is an endogenous unsaturated fatty acid produced by Pseudomonas metabolite. aeruginosa. (Z)-2-decenoic acid induces a dispersion response in biofilms formed by a range of gram-negative bacteria, including P. aeruginosa, and by gram-positive bacteria. Purity: 99.46% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 1 mg, 5 mg 4 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected] (Z)-Aconitic acid (±)-Alliin (cis-Aconitic acid) Cat. No.: HY-W016814 ((±)-L-Alliin) Cat. No.: HY-126085 (Z)-Aconitic acid (cis-Aconitic acid) is the (±)-Alliin is the main active component of garlic.
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