Anti-RHBDF1 monoclonal antibody (DCABH- 201362) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description RHBDF1 (rhomboid 5 homolog 1 (Drosophila)) is a -coding . Diseases associated with RHBDF1 include fgfr-related craniosynostosis syndromes, and craniosynostosis, syndromic. GO annotations related to this gene include growth factor binding and serine-type endopeptidase activity. An important paralog of this gene is RHBDF2. -like protein which has no protease activity but regulates the secretion of several ligands of the epidermal growth factor receptor. Indirectly activates the epidermal growth factor receptor signaling pathway and may thereby regulate sleep, cell survival, proliferation and migration.

Immunogen A synthetic peptide of human RHBDF1 is used for rabbit immunization.

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Protein A

Conjugate Unconjugated

Applications WB, ELISA

Size 1 mg

Buffer In 1x PBS, pH 7.4

Preservative None

Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

GENE INFORMATION

Gene Name RHBDF1 rhomboid 5 homolog 1 (Drosophila) [ Homo sapiens (human) ]

Official Symbol RHBDF1

Synonyms RHBDF1; rhomboid 5 homolog 1 (Drosophila); Dist1; hDist1; C16orf8; EGFR-RS; gene-89;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved gene-90; inactive rhomboid protein 1; iRhom1; p100hRho; rhomboid family 1; rhomboid family member 1; epidermal growth factor receptor-related protein; epidermal growth factor receptor, related sequence;

Entrez Gene ID 64285

Protein Refseq NP_071895

UniProt ID Q96CC6

Chromosome Location 16p13.3

Function growth factor binding; NOT serine-type endopeptidase activity;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved