AMREP Research Report 2011
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The Global Eradication of Smallpox and the Work of Frank Fenner
In Focus The global eradication of smallpox and the work of Frank Fenner CR Robert George and William Rawlinson Virology Division, SEALS Microbiology Prince of Wales Hospital Randwick, NSW 2031, Australia Email: [email protected] The 1950s and 1960s represented a golden era in scientific poxvirus research. Multiple obituaries document his life, achieve- – discovery when many believed science would solve the ments, and his death in November 20102 10. world’s greatest problems. It was the era when colour tele- A DNA virus called variola (Orthopoxvirus, Poxviridae) causes vision was introduced and the role of DNA described, space smallpox. Case fatality rates varied depending on the infection type, programmes, the introduction of vaccines for polio, measles reaching up to 30% in the historically most common form variola and mumps, and the structures of proteins began to be major11. Smallpox has influenced the course of history and deci- described. Many discoveries were controversial, but there mated populations. For example, historians have debated whether was a strong belief science was taking the world forward and up to one-third of the Aztec population was decimated by smallpox reducing medical problems rapidly. The Intensified Small- in 1520 after Hernando Cortes accidently introduced the virus thus pox Eradication Program (ISEP) won united support from facilitating the European conquest of South America12. Elsewhere, both the Union of Soviet Socialist Republics (USSR) and the native Virginian inhabitants were depopulated to one-third of their United States of America (USA). The initiative was passed by former number in 1689, and numerous North American tribes were only a small margin (two votes) and came on the back of affected13. -
Scientists' Houses in Canberra 1950–1970
EXPERIMENTS IN MODERN LIVING SCIENTISTS’ HOUSES IN CANBERRA 1950–1970 EXPERIMENTS IN MODERN LIVING SCIENTISTS’ HOUSES IN CANBERRA 1950–1970 MILTON CAMERON Published by ANU E Press The Australian National University Canberra ACT 0200, Australia Email: [email protected] This title is also available online at http://epress.anu.edu.au National Library of Australia Cataloguing-in-Publication entry Author: Cameron, Milton. Title: Experiments in modern living : scientists’ houses in Canberra, 1950 - 1970 / Milton Cameron. ISBN: 9781921862694 (pbk.) 9781921862700 (ebook) Notes: Includes bibliographical references and index. Subjects: Scientists--Homes and haunts--Australian Capital Territority--Canberra. Architecture, Modern Architecture--Australian Capital Territority--Canberra. Canberra (A.C.T.)--Buildings, structures, etc Dewey Number: 720.99471 All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, mechanical, photocopying or otherwise, without the prior permission of the publisher. Cover design by Sarah Evans. Front cover photograph of Fenner House by Ben Wrigley, 2012. Printed by Griffin Press This edition © 2012 ANU E Press; revised August 2012 Contents Acknowledgments . vii Illustrations . xi Abbreviations . xv Introduction: Domestic Voyeurism . 1 1. Age of the Masters: Establishing a scientific and intellectual community in Canberra, 1946–1968 . 7 2 . Paradigm Shift: Boyd and the Fenner House . 43 3 . Promoting the New Paradigm: Seidler and the Zwar House . 77 4 . Form Follows Formula: Grounds, Boyd and the Philip House . 101 5 . Where Science Meets Art: Bischoff and the Gascoigne House . 131 6 . The Origins of Form: Grounds, Bischoff and the Frankel House . 161 Afterword: Before and After Science . -
2006 Annual Report, My First As Improving Links with and Transfer of Information to and from Our Partners, Director
ANNUAL REPORT 2006 The Menzies School of Health Research (MSHR) was established in 1985 as a body corporate of the Northern Territory (NT) Government under the Menzies School of Health Research Act 1985 (The MSHR Act). This act was amended in 2004 to formalise the relationship with Charles Darwin University (CDU). MSHR is now a controlled-entity of CDU and constitutes a school within the university’s Institute of Advanced Studies. Timika Dili Darwin MSHR Darwin Headquarters Alice Springs Menzies staff and facilities are uniquely positioned to conduct We also operate a smaller unit in Alice Springs co-located with active research across the country’s tropical north, throughout the Centre for Remote Health, and a joint research facility with remote Indigenous communities, and in partnership with our the Indonesian Ministry of Health’s National Institute of Health neighbouring countries to the north. Research and Development, in Timika, Indonesia. MSHR headquarters are located on the Royal Darwin Hospital Campus, providing office accommodation for the majority of our In the spirit of respect, Menzies School of Health Research staff and students. It also houses a well equipped and highly acknowledges the people and elders of the Aboriginal and regarded laboratory with (PC2 and PC3 containment facilities), Torres Strait Islander Nations, who are the Traditional Owners conducting leading edge science ranging from analysis of of the land and seas of Australia. snake venom, soil samples for Melioidosis, scabies mite drug resistance to pathogenicity of streptococci. For the purpose of this document ‘Indigenous’ refers to Australia’s Aboriginal and Torres Strait Islander peoples. -
What Price Australian Naway and an R Ami I R Fugees, 'Illegals' AUSTRALIAN BOOK REVIEW
The Vatic -Edmund Campion on the Australia What price Australian naway and An r ami I r fugees, 'illegals' AUSTRALIAN BOOK REVIEW SEPTEMBER: Humphrey McQueen on Chris wattace~-Gra th e Chinese connecti on Dorothy Porter, Michael Hofmann, Fay Zwicky, Anthony Lawrence, Rolling Column by Mark Davis Anita Heiss, Merlinda Bobis, Tien Hoang Nguyen, Deb Westbury, Kerryn Goldsworthy on Thea Astley' s MTC Cronin, Dry lands Geoff Goodfellow and many mo re Marilyn Lake on Beryl Beaurepajre I melbourne Mari on Halli gan on Andrew Riemer's new memoir festival of Subscribers $55 for ten issues plus a free book Ph (03) 9429 6700 or Fax (03) 9429 2288 poetry september Art Monthly 1999 AUSTRALIA IN THE SEPTEMBER ISSUE chapel off Peter Hill interYiews Liz Ann Macgregor, new Director of the Museum of chapel Contemporary Art • prahran Daniel Thomas talks about being a curator 9522 3382 ArtRage - Mat Gallois on r;"t.,~;:;:;::::;-;;;;;::rn!l:;n~..r.w,,.,;::;;=rr-""""IIPII Off Chapel being an emerging artist in Sydney inHiative supported by Arts The Immigration Museum and the Victoria Millionth Migrant exhibition Out now _ S-1.9.'i, .fimn good boohlwps and ncii'Sagcnls. Or plu111c ()] 62-19 3986 jin· your mbsaiption Volume 9 Number 7 September 1999 A magazine of public affairs, the arts and theology CoNTENTS 4 COMMENT With Mark McKenna and 32 Francis Sullivan. AFTER THE BIG WAVE Photographic essay by Peter Davis. 'He loved to 7 speculate, CAPITAL LETTER 34 INDONESIAN WITNESS sometimes almost 8 Peter Mares interviews Ibu Sulami, dangerously, LETTERS activist, feminist and political survivor. -
Investigation Into the Cardiotoxic Effects of B- Adrenergic Receptor Agonists in Myocardial Ischaemia/Reperfusion Injury
Investigation into the cardiotoxic effects of b- adrenergic receptor agonists in myocardial ischaemia/reperfusion injury Nagra, A. S. Submitted version deposited in Coventry University’s Institutional Repository Original citation: Nagra, A. S. (2016) Investigation into the cardiotoxic effects of b- adrenergic receptor agonists in myocardial ischaemia/reperfusion injury. Unpublished PhD Thesis. Coventry: Coventry University Copyright © and Moral Rights are retained by the author. A copy can be downloaded for personal non-commercial research or study, without prior permission or charge. This item cannot be reproduced or quoted extensively from without first obtaining permission in writing from the copyright holder(s). The content must not be changed in any way or sold commercially in any format or medium without the formal permission of the copyright holders. Some materials have been removed from this thesis due to third party copyright. Pages where material has been removed are clearly marked in the electronic version. The unabridged version of the thesis can be viewed at the Lanchester Library, Coventry University. Investigation into the cardiotoxic effects of b- adrenergic receptor agonists in myocardial ischaemia/reperfusion injury By Aarondeep Singh Nagra January 2016 Supervisory team: Dr. Afthab Hussain, Professor Helen Maddock & Dr. Christopher Mee A thesis submitted in partial fulfilment of the University’s requirements for the Degree of Doctor of Philosophy Acknowledgements I would like to give thanks to my supervisory team Dr. Afthab Hussain, Professor Helen Maddock and Dr. Christopher Mee, whose guidance throughout has been invaluable allowing me to confidently go on to complete my thesis. I would also like to give special thanks to my colleagues; Mayel Gharanaei, Jawad Khan, Katherine Harvey and Maryam Babba for making our time in the lab together a period for us all to look back on and reminisce the good times. -
Interviews Exclusives Chroniques
ACTUALITÉS LIVE REPORTS INTERVIEWS CHRONIQUES .com mai/juin 2015 N° 5 magazine INTERVIEWS CHRONIQUES EXCLUSIVES no return, shuffle, klone, wyld, DEEP IN HATE warning, miss america band, Blazing War Machine snake eye, deadly scenes .com Nous revoilà avec moins de pages… Aïe ! Mais c’est toujours gratos ! Nous sommes fiers d’être Français ! D’être une belle démocratie libre et fiers d’avoir d’excellents musiciens, artistes, créateurs, auteurs, compositeurs, interprètes, producteurs, éditeurs, illustrateurs, photographes, journalistes, réalisateurs, des humoristes rebels, tout simplement des acteurs de la scène vivante de talents, des gens de bonne volonté qui se bougent le cul aussi pour organiser des grosses tournées comme : Fred Chouesne (Garmonbozia, interview prochainement sur le site), produire des gros festivals comme le fameux Ben Barbaud (Le Hellfest, interview vidéo sur le site), pour des tas de Metal Rock Maniacs exigeants, comme vous et nous ! Dynamiques Français et Françaises qui sont fin prêts aux combats ! La France a enfin des festivals dignes de ses ambitions avec le fameux Hellfest (qui est complet depuis des mois !), Photo : Carlos Sancho le Motocultor qui grossi, le Raismes Fest qui tient le pavé, le Fall Of Summer Festival II, le South Metal Fest, l’Extreme Factory Festival, Le Heart Sound Metal Festival 2015 qui démontre aussi que les rockeurs on du coeur, etc.… Même en temps de crise, nos artistes compatriotes nous envoient des tonnes d’albums f-a-n-t-a-s-t-i-q-u-e-s ! Mais nous ne traiterons pas seulement des artistes -
Track 5: Cardiology and the Imaging Revolution
TRACK 5: CARDIOLOGY AND THE IMAGING REVOLUTION Volume 10 • Number 1 Abstract no: 1 Summer 2013 Real time 3-D echocardiographic characteristics of left ventricle and left atrium in normal children Bao Phung Tran Cong, Nii Masaki, Miyakoshi Chihiro, Yoshimoto Jun, Kato Atsuko, Ibuki Keichiro, Kim Sunghae, Mitsushita Norie, Tanaka Yasuhiko and Ono Yasuo Cardiac Department, Shizuoka Children’s Hospital, Shizuoka, Japan Background: The accurate assessment of left atrial (LA) and/or left ventricular (LV) volume and contractility is crucial for the management of patients with congenital heart disease. The real time 3-dimensional echocardiography (RT3-DE) is reported to show better correlation with magnetic resonance imaging (MRI) in estimating LV and LA volume than conventional 2-dimensional echocardiography (2-DE). On the other hand, the volume measurement in RT3-DE is also reported to be significantly smaller than those in MRI, necessitating the establishment of normal values of RT3-DE itself. Aim: To identify the normal values of LV and LA volume measured by RT3-DE in Japanese children. Methods: Sixty four normal school students (age: median 9.6 years; range (5.5 - 14.5); male 26, female 38) were enrolled in this study. End-diastolic and end- systolic LV and LA volumes were analysed using M-mode in short-axis view, 2-D biplane method, and RT3-DE. We used IE-33 (PHILIPS) with matrix probe X7 and X4. Off-line assessment to calculate LA and LV volume was done using QLAB 8.1 (Philips). Results: Forty nine children (age: median 9.1 years, range (6 - 14); male 21, female 28) had adequate RT3-DE data sets and were analysed. -
AMREP Research Report 2013
The Alfred Medical Research and Education Precinct Research Report 2013 Report Research Precinct and Education Research Medical The Alfred 2013 AMREP RESEARCH REPORT The Alfred Medical Research & Education Precinct Alfred Medical Research and Education Precinct Commercial Road, Melbourne, Victoria 3004, Australia www.amrep.org.au The Alfred Medical Research and Education Precinct The Alfred Medical Research and Education Precinct - AMREP - is a partnership between Alfred Health, Monash University, Baker IDI Heart and Diabetes Institute, Burnet Institute, La Trobe University and Deakin University. AMREP is located on the campus of The Alfred hospital, Melbourne. Alfred Medical Research and Education Precinct Commercial Road Melbourne, Victoria 3004 Australia © Alfred Health 2014 www.amrep.org.au This work is copyright. Apart from any use as permitted under the Copyright Act 1968, no part of this Acknowledgements publication may be reproduced by any process without prior written permission from Alfred Health. Produced by Research Office, Alfred Health and Baker IDI Heart and Diabetes Institute ISSN 1445-8853 Design by abCreative | abCreative.com Contents Professor Brendan Crabb AMREP Highlights 2013/2014 2 Director and CEO, Research Outputs 4 Burnet Institute Human Ethics and Research Governance 6 Chair, AMREP Council Animal Ethics 7 Baker IDI Heart and Diabetes Institute 8 It is with great pleasure that I introduce the AMREP Research Report for 2013. I would like to take this Nucleus Network 14 opportunity to congratulate all AMREP partners on a Burnet Institute 16 successful year of research endeavour. Monash School of Public Health and Preventive Medicine 22 AMREP has continued to perform strongly, with increased Epidemiology and Preventive Medicine 23 levels of publications in peer-reviewed journals and, Centre for Obesity Research and Education 24 although more difficult to quantify, we have made strong progress in the translation of our research. -
Pathway #13 - Text 15/8/07 6:52 PM Page 16
PathWay #13 - Text 15/8/07 6:52 PM Page 16 in profile A life of distinction MICROBIOLOGY MARVEL PROFESSOR FRANK FENNER IS ONE OF AUSTRALIA’S MOST VENERATED SCIENTISTS – AND A VERY HUMBLE MAN, FINDS MELISSA SWEET. fter a stellar career spanning seven or graces. Just a quiet and simple: Poxes – small, rodent Adecades, Professor Frank Fenner has “Fenner.” and rabbity begun the difficult task of packing up his If you didn’t know his pedigree, you office – almost 30 years after his official After the war, he worked alongside Sir would swear that the blue-eyed, white- retirement. Macfarlane Burnet at the Walter and Eliza haired gent shuffling down the corridor When Professor Fenner finally vacates Hall Institute of Medical Research in could be anyone’s grandfather. What his room at The John Curtin School of Melbourne, where he studied mousepox, gives him away is the affection and Medical Research in Canberra, as he a close relative of the smallpox virus. It respect that is so evident in the greetings intends to later this year, it will be the end was the beginning of a lifelong interest in from colleagues. of an era for Australian science and for pox viruses. one of its most revered figures. When awarded an honorary fellowship Much of his first 15 years at the ANU “I really have to go home and get of the Royal College of Pathologists of were absorbed by research into another things in order,” Professor Fenner Australasia (RCPA) earlier this year, the pox virus – myxomatosis. explains. citation noted that the award recognised This work, which contributed to the After all, he will be 93 in December not only Professor Fenner’s scientific and control of the rabbit plague that had and doesn’t expect to be able to continue medical contributions, but also the decimated the Australian countryside, is his current routine – rising at 5am, reading tenacity and humble nature of the man widely judged as one of his key the latest journals until 8am and then behind the work. -
The Rockefeller Institute Quarterly 1957, Vol.1, No. 4 the Rockefeller University
Rockefeller University Digital Commons @ RU The Rockefeller Institute Quarterly The Rockefeller University Newsletters 12-1957 The Rockefeller Institute Quarterly 1957, vol.1, no. 4 The Rockefeller University Follow this and additional works at: http://digitalcommons.rockefeller.edu/ rockefeller_institute_quarterly Recommended Citation The Rockefeller University, "The Rockefeller Institute Quarterly 1957, vol.1, no. 4" (1957). The Rockefeller Institute Quarterly. Book 2. http://digitalcommons.rockefeller.edu/rockefeller_institute_quarterly/2 This Book is brought to you for free and open access by the The Rockefeller University Newsletters at Digital Commons @ RU. It has been accepted for inclusion in The Rockefeller Institute Quarterly by an authorized administrator of Digital Commons @ RU. For more information, please contact [email protected]. THE ROCKEFELLER VOLUME 1 NUMBER 4 DECEMBER 1957 LIBRARY OF A SCHOLAR Die Alpen, one of the first works to present mountains to the public as objects of senti- ment and interest rather than of horror. BEQUEATHED TO THE INSTITUTE And before he was ten it is said that he had sketched out a Chaldean grammar! THEBOOKS which he had collected and names in the history of medical science, One of the delights of Dr. Cohn's old treasured throughout his life were be- often in first editions: Celsus, Thomas books, however, is that works from quite queathed by the late Dr. Alfred E. Cohn Bartholinus, G. Borelli, Malpighi, Leu- unexpected sides of well-known men are to the Rockefeller Institute where -
Chris Coleman and Other Sonor Artists in the Development of This New Drum Series
FEEL THE SOUND. When we design drums, our intention is to con- shell came out as a clear winner in all test situations. tinuously improve the acoustic quality in any Then we went out to look for a birch variety that would given situation. We do not stop at wood selec- meet our CLTF and OSM shell making standards and tion or shell configuration. Many factors influence the found a unique European birch that stood up to these acoustic performance: shell material and construction, demands. drum head selection, tuning, mounting, room acoustics, individual perception and much more. For SQ1 we worked closely with Chris Coleman and other Sonor artists in the development of this new drum series. The input from a professional players point of view provided many important insights. As a first step we looked for a shell material that would meet the request for a very balanced sound. Our choice was birch because of its characteristic high end frequencies and clearly defined low-end. In blindfold tests we tried many different types of shell construc- tion, from pure birch to hybrid versions. The pure birch SQ1 shell made of pure European birch THE STORY BEHIND CLTF AND OSM Drum shells need to act as solid acoustic unities as the foundation Our OSM shell construction (Optimum Shell Measurement) for a great drum sound. We use cross-laminated plies of birch to utilizes slightly undersized shell diameters to give the drum form a perfectly round shell with great stability. head the space to float freely, allowing Each ply is laminated at a 90° angle unrestricted contact between to allow for a shell that is tension- the bearing edge and the drum free. -
In Memoriam: Frank John Fenner (1914–2010) Frederick A
IN MEMORIAM In Memoriam: Frank John Fenner (1914–2010) Frederick A. Murphy rank John Fenner (Figure), one of the world’s most Fdistinguished virologists and a dear friend of many colleagues around the world, died in Canberra, Australia, on November 22, 2010, at the age of 95. This In Memoriam must be different from those usually published here. After all, quite detailed pieces are anticipated from the Australian Academy of Sciences, the Royal Society, et al., and Frank had published a comprehensive autobiography (1). Thus, there is opportunity to present personal memories, hoping to provide more of a sense of the man, the colleague, and the friend of so many members of the global virology community. This tribute seems to fi t in with the closing paragraphs of Frank’s autobiography, in which he refl ects on friendship and special friends. Frank was born in Ballarat, Victoria, Australia, but his family moved to Adelaide, South Australia, when he Figure. Frank Fenner at the John Curtin School of Medical was 2 years old. He received a bachelor of medicine and Research, Canberra, Australia, inoculating embryonating eggs with surgery degree (1938) and a doctor of medicine degree myxoma virus, 1950. Used with permission of the John Curtin School of Medical Research. (1942) at the University of Adelaide. During 1940–1946, he was an offi cer (Captain, Major) in the Australian Army Medical Corps and served in Australia, Palestine, Egypt, New Guinea, and Borneo. At various times, he worked as a worked on Mycobacterium tuberculosis, Frank worked on medical offi cer in a fi eld ambulance and casualty clearing M.