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Curriculum Vitae

Takahiro Shiota, MD, PhD, FACC, FESC, FASE, FAHA

Office Address: Cedars-Sinai Medical Center Institute 127 S. San Vicente Blvd., A3411 Los Angeles, CA 90048 (310) 423-6889 Office Email: [email protected]

EDUCATION:

1991 Ph.D. in . Faculty of Medicine, University of Tokyo, Tokyo, Japan 1977-1983 M.D. Faculty of Medicine, University of Tokyo, Tokyo, Japan 1972-1976 B.S. in Physics. Faculty of Science, University of Tokyo, Tokyo, Japan

LICENSURE AND CERTIFICATION

National Board of (#2000-252) California Medical License (#000015) Ohio Medical License (#35. 080318) ECFMG (#0-576-045-9) Japanese Medical License (#274951)

PROFESSIONAL EXPERIENCE

1/2009-present Associate Director Division of Noninvasive Cardiology Cedars-Sinai Heart Institute Los Angeles, CA

12/2001-12/2008 Clinical Staff Department of Cardiovascular Medicine Cleveland Clinic, Cleveland, OH

7/1999-11/2001 Advanced Cardiac Department of Cardiovascular Medicine Imaging Fellow Cleveland Clinic, Cleveland, OH

9/1997- 6/1999 Project Staff Department of Cardiovascular Medicine 2

Cleveland Clinic, Cleveland, OH

8/1992- 8/1997 Research Director Laboratory, Clinical Care Center for Congenital Heart Disease, Oregon Health Sciences University, Portland, OR PROFESSIONAL ACTIVITIES:

Academic Appointment

7/2009-present Professor of Medicine, Department of Medicine, Cedars-Sinai, Los Angeles, CA

8/2008-present Clinical Professor of Medicine, David Geffen School of Medicine at UCLA

7/2007-12/2008 Professor of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH

7/2004-6/2007 Associate Professor of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH

6/2000-6/2004 Associate Professor of Medicine, Cleveland Clinic Health Sciences Center, Ohio State University School of Medicine, Columbus, OH

7/1997-8/1997 Associate Professor of Medicine, Clinical Care Center for Congenital Heart Disease, Department of Pediatric Cardiology, Oregon Health Sciences University, Portland, OR

7/1993-6/1997 Assistant Professor of Medicine, Clinical Care Center for Congenital Heart Disease, Department of Pediatric Cardiology, Oregon Health Sciences University, Portland, OR

8/1992-6/1993 Instructor, Clinical Care Center for Congenital Heart Disease, Department of Pediatric Cardiology, Oregon Health Sciences University, Portland, OR

Society Memberships

1996-Present Fellow of the American College of Cardiology (F.A.C.C.) 2007-Present Fellow of the American Heart Association (F.A.H.A.) 2008-Present Fellow of the European Society of Cardiology (F.E.S.C.) 1996-Present Fellow of the American Society of Echocardiology (F.A.S.E.) 3

Other Professional Activities

1/1/14-Present Board Member of IRB at Cedars Sinai Medical Center 2013-Present Vice President, Asian-Pacific Association of Echocardiography 1/1/13-Present Vice President, Asian-Pacific Association of Echocardiography 1/1/12-12/31/13 President, Los Angeles Society of Echocardiogrphy 1/1/11-Present International Advisory Board Member, Journal of Japanese College of Cardiology 1/1/10-Present International Task Force Representative to Japan, American Society of Echocardiography 1/1/09-12/31/10 Scientific Advisory Board Member, International Academy of Cardiology 1/1/08-12/31/2013 Editor-in-Chief, “Cardiac Ultrasound Today” 9/1/05-8/31/09 Quality Assurance Officer in Cardiology at Cleveland Clinic 1993-Present Abstract grader and peer reviewer for Circulation, Journal of the American College of Cardiology, American Heart Journal, American Journal of Cardiology and Journal of the American Society of Echocardiography.

HONORS

2007 “America’s Top Cardiologists” 2014 Highly Commended for 3D Echocardiography 2nd edition at the British Medical Association Medical Book Awards

GRANT SUPPORT:

1. R01HL122492 (PI – Chugh, Co-Investigator-Takahiro Shiota) NIH NHLBI Total Costs: $ 2,357,464 Sudden Cardiac Death in Middle Age This study is a population-based translational approach to identify novel mechanisms of ventricular arrhythmogenesis in middle-aged residents of a large community. 11/14/14 – 11/13/18

2. Grant-in-Aid, American Heart Association, Ohio Valley Affiliate. 3-Dimensional echocardiographic evaluation of the heart: Quantitative application for valvular heart disease. Role on Project: Principal Investigator 7/1/99-6/30/01

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3. National Aeronautics and Space administration. Digital echocardiography in manned space flight: remote diagnosis and quantitative analysis. Role on Project: Co- Investigator. P.I. James D. Thomas, MD. 7/1/97-6/30/99

4. Grant-in-Aid, American Heart Association, Oregon Affiliate. 3-Dimensional modeling of cardiac flow events as imaged by color . Role on Project: Principal Investigator 7/1/97-6/30/99

5. PHS NIH NHLBI (R01 HL43287). Multicenter study of miniaturized multiplane TEE probes. Role on Project: Co-Investigator. P.I. David J. Sahn, MD. 2/1/95- 1/31/98

6. PHS NIH NHLBI (R01 HL36472). Phase array for multiplane esophageal echos in infants. Role on Project: Co-Investigator. P.I. David J. Sahn, MD. 8/1/87-1/31/96

7. PHS NIH NHLBI (R01 HL43287). Improved understanding of cardiac flows. Role on Project: Co-Investigator. P.I. David J. Sahn, MD. 9/1/90-8/31/95

CURRENT RESEARCH PROJECTS

4/1/14-Present Geometry of Postinfarction Ventricular Septal Defect in Comparison with Congenital Ventricular Septal Defect: A Real-Time Three- Dimensional Transesophageal Echocardiography Study.

6/1/14-Present Volume Reduction of Mitral Regurgitation is Main Contributor to Increase of Cardiac Forward Flow in Patients with Preprocedural Mitral Regurgitation after Transcatheter Replacement: Hemodynamic analysis using echocardiography.

8/1/14-Present Absence of Chordae Tendineae near Valve Coaptation Leads to Mitral Regurgitation in Lone Atrial Fibrillation.

INVITED SPEAKER, MODERATOR AND CHAIRPERSON

1. Cardiology Grand Rounds: University of Illinois, Chicago, April 1993. "Quantitation of Mitral Regurgitation Using Doppler Echocardiography"

2. 8th Annual Advances in Echocardiography, Chicago, September 1993.

3. Topics of Faculty Science: Oregon Health Sciences University, Congenital Heart Research Center, February 1994 “Contrast Echocardiography”

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4. Topics of Faculty Science: Oregon Health Sciences University, March 1994. "Color Doppler flow convergence region of mitral regurgitation"

5. 9th Annual Advances in Echocardiography, Chicago, September 1994.

6. Topics of Faculty Science: Oregon Health Sciences Universitiy, March 1995. “Three-Dimensional Color Doppler Echocardiography”

7. 43rd Annual Scientific Meeting of Japanese College of Cardiology; Yokohama, Japan, September 1995. "Doppler Flow Convergence Quantitation in Aortic and Mitral Regurgitation"

8. 10th Annual Advances in Echocardiography, Chicago, September 1995.

9. Topics of Faculty Science: Oregon Health Sciences University, November 1995. "Digital Phonocardiography of Mitral Regurgitation"

10. Anesthesiology Conference: Oregon Health Sciences University, December 1995. "Three-Dimensional Echocardiography Using Multi-plane Transesophageal Echocardiography"

11. 11th Annual Advances in Echocardiography, Chicago, September 1996.

12. 8th Annual Scientific Sessions of American Society of Echocardiography: Florida, June 1997. Meet the Expert “Automated Cardiac Flow Measurement”

13. Contrast Echocardiography Conference of Japanese Society of Echocardiography: Osaka, Japan, August 1997. “New Development of Contrast Echocardiography”

14. 14th Annual Advances in Echocardiography, Chicago, September 1997.

15. 9th Annual Scientific Sessions of American Society of Echocardiography: San Francisco, June 1998. Meet the Expert “Model Study”

16. 70th Scientific Sessions of American Heart Association, Moderator, How to Session :Dallas, Novemver 1998. “3D Echocardiography, the Past, the Present and the Future”

17. 10th Annual Scientific Sessions of American Society of Echocardiography: Washington DC, June 1999. Symposium “3D Echocardiography”

18. Echo Kobe 2000 Conference of Japanese Society of Echocardiography: Kobe, Japan, July 2000. “Case Studies with Experts” “Echocardiographic Qunatification of Cardiac Function in the Year of 2000” 6

19. Contrast Echocardiography Conference of Japanese Society of Echocardiography: Osaka, Japan, August 2000. “Clinical Applications of Contrast Echocardiography”

20. Cardiothoracic Surgical Grand Rounds, Saitama College of Medicine, Japan, August 2000. “ with Echocardiography”

21. Cardiology Grand Rounds: Kawasaki College of Medicine, Kurashiki, Japan, August 2000. “Three Dimensional Echocardiography”

22. 15th Annual Advances in Echocardiography, Chicago, September 2000. “3D Stress Contrast Echocardiography”

23. Cardiology Grand Rounds: Faculty of Medicine, University of Kagoshima, Kagoshima, Japan, August 2001. “3D Echocardiography”, “Medical Education in the United States”

24. American Society of Echocardiography, Faculty and Moderator, Seattle, June 2001. “New Technology”

25. Echo Kobe 2001, Conference of Japanese Society of Echocardiography, Kobe, Japan. July 2001. “3D Echocardiography”, “Case Studies at Cleveland Clinic”

26. Cardiology Grand Rounds: Kawasaki College of Medicine, Kawasaki, Japan, August 2001. “Case studies at Cleveland Clinic”

27. Cardiology Grand Rounds, Faculty of Medicine, University of Kagoshima, Kagoshima, Japan, August 2001 “3D Echocardiography”, “Medical Education in the United States”

28. The Meeting, Cleveland Clinic, Cleveland, OH, September 2001. “3D Echocardiography of Mitral Valve, Live Demo”

29. Co-Chairman of a session of American College of Cardiology Meeting, Atlanta, March 2002. “3D Echocardiography”

30. 8th Annual Meeting of Fetal Echocardiography, Akita, Japan, February 2002. “Echocardiographic Evaluation of Cardiac Function: Recent Developments”

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31. Cardiology Grand Rounds, 2nd Department of Internal Medicine, Akita University, Akita, Japan, February 2002. “Clinical Application of 3D Echocardiography “

32. Contrast Echocardiography & New Technologies, Cleveland, OH, May 2002. “3D Echocardiography”

33. Echo Kobe 2002, Japanese Society of Echocardiography, Kobe, Japan. July 2002. “Echocardiography in ”, “Case studies at Cleveland Clinic”

34. Cardiology Grand Rounds: Kawasaki College of Medicine, Kawasaki, Japan, July 2002. “Clinical Management of Cardiac Patients at Cleveland Clinic”, “Medical Education and Evaluation of Physicians in the United States”

35. Cardiology Grand Rounds: Faculty of Medicine, Yamaguchi University, Yamaguchi, Japan, July 2002. “Echocardiography at Cleveland Clinic”

36. European Society of Cardiology, Berlin, Germany, September 2002. “3D Echocardiography”

37. Faculty of Medicine, Osaka City University, Osaka, Japan, August 2002. “Clinical Echocardiography at Cleveland Clinic”

38. Saitama College of Medicne, Saitama, Japan, August 2002. “Surgical Application of Echocardiography at Cleveland Clinic”

39. National Cardiovascular Center, Osaka, Japan, August 2002. “Echocardiography in Heart Failure at Cleveland Clinic”, “3D Echocardiography”

40. European Society of Echocardiography, Munich, Germany, December 2002. “3D Echocardiography in Hypertrophic Cardiomyopathy”

41. Contrast Echocardiography & New Technologies, Cleveland, OH, May 2003. “3D Echocardiography: Useful or Just Pretty Pictures?”

42. Echo Kobe, Japanese Society of Echocardiography, Kobe, Japan, July 2003. “Intraoperative Echocardiography”, “Case Studies at Cleveland Clinic”

43. First Annual meeting of Advanced Doppler Echocardiography, Tokyo, Japan, August 2003. “3D Echocardiography”

44. European Society of Echocardiography, Barcelona, Spain, December2003. 8

“Left Function”

45. 13th Annual meeting of Indonesian Heart Association, Bali, Indonesia, February 2004. “Clinical Application of 3D Echocardiography”

46. University of Barcelona, Barcelona Spain, April, 2004. “3D Echocardiography in LV remodeling” “Hypertrophic Cardiomyopathy”

47. Echo Kobe, Japanese Society of Echocardiography, Kobe, Japan, July 2004. "Ischemic Mitral Regurgitation" "Intraoperative Transesophageal Echocardiography" "Interesting Cases at Cleveland Clinic" "3D Echocardiography"

48. Faculty of Medicine, Osaka City University, Osaka, Japan, July 2004. "Clinical and Research Echocardiography at Cleveland Clinic"

49. Cardiothoracic Surgical Grand Rounds, Saitama College of Medicine, Saitama, Japan, July 2005. “Echocardiography for Ischemic MR”

50. Faculty of Medicine, Dokkyo University, Saitama, Japan, July 2005. “Functional valvular regurgitation”

51. Faculty of Medicine, Osaka City University, Osaka, Japan, July 2005. “Ischemic Mitral Regurgitation”

52 13th Annual Meeting of Japanese , Tokyo, Japan, July 2005. “Echocardiography for CAD”

53. Echo Kobe, Japanese Society of Echocardiography, Kobe, Japan, July 2005. “Intra-operative TEE” “ Echo for Myocardial Infarct”

54. Cardiology Grand Rounds: Kawasaki College of Medicine, Okayama, Japan, July 2005. “Case Presentations of Ischemic Cardiomyopathy in the United States”

55. Cardiology Grand Rounds, Faculty of Medicine, University of Kagoshima, Kagoshima, Japan, August 2005. 9

“Medical Education in the United States”

56. Chilean Society of Ultrasound, Santiago, Chile, October 2005. “3-D Echocardiography”

57. American Heart Association, Dallas, TX, Novermber 2005. “3-D Echocardiography”

58. Consorzio ECM Event, Rome, Italy, June 2006. “Differences in the Patho-Physiology of Functional Mitral Regurgitation Between Ischemic and Dilated Cardiomyopathy” Moderator: “Treatment Options”

59. 17th Annual Meeting of Japanese Society of Echocardiography, Saitama, Japan, April 2006. “3D Echocardiography”

60. Cardiology Grand Rounds: Kawasaki College of Medicine, Okayama, Japan, July 2006. “Case Presentations of Ischemic Cardiomyopathy in the United States”

61. American Heart Association, Chicago, IL, November 2006. “New Technology”

62. 12th Asian-Pacific Congress of Doppler and Echocardiogrpahy, Chengdu, China, October, 2007 “Clinical Value of 3D Echocardiography” “Echocardiographic Evaluation of Ischemic Mitral Regurgitation”

63. American Heart Association, Orlando, FL, November 2007. “3D Echocardiography”

64. 72th Annual Meeting of Japanese Circulation Society, Fukuoka, Japan, March, 2008. “Clinical Value of Color Doppler 3D Echocardiography”

65. American College of Cardiology, Chicago, IL, March 2008. “3D Echocardiography in Hypertrophic Cardiomyopathy”

66. 16th Congress of the International Cardiac Doppler Society, Kobe, Japan, April 2008. “New Development of 3D Echocardiography”

67. 19th Annual Meeting of Japanese Society of Echocardiography, 10

Kobe, Japan, April 2008 “Echocradiographic Analysis of Ischemic Mitral Regurgitation” “Roles of Intra-operative TEE”

68. 19th Annual Scientific Meeting of Japanese College of Cardiology, Tokyo Japan, September 2008. “Non-Surgical Management of Valvular Heart Disease” “Role of Physician Assistant in the United States”

69. American Heart Association, Orlando, FL, November 2009. “Three-Dimensional Echocardiography: Methodology and Applications”

70. American Heart Association, Orlando, FL, November 2009. “Real-Time 3D Echocardiography”

71. American Heart Association, Orlando, FL, November 2009. “Emerging Applications of 3D Echocardiography”

72. Los Angeles Society of Echocardiography, Los Angeles, CA, May 2010. “Echocardiographic Evaluation of the Right

73. Tokyo Echo Lab, Tokyo, Japan, Dec 2010. “Transcatheter Aortic Valve Implantation and MitraClip”

74. Kawasaki College of Medicine, Kurashiki, Japan, Dec 2010. “3D Echocardiography”

75. Annual Scientific Meeting of the Japanese Society of Echocardiography, Kagoshima, Japan, April 2011. “Transcatheter Aortic Valve Implantation” “Role of Echocardiography in the age of Percutaneous Device Procedure” “ 3D Echocardiography”

76. Kawasaki College of Medicine, Kurashiki, Japan, April 2011. “Clinical Significance of Real-Time 3D Transesophageal Echocardiography”

77. Annual Meeting of the Conference of Advanced Cardiovasucular Ultrasoud, Osaka, Japan, Aug 2011. “Echocardiographic Guidance of Therapeutic Approaches for Valvular Heart Disease”

78. Univ of Occupational & Environmental Health, Kitakyushu, Japan, Aug 2011. “Role of physician investigators in the U.S.”

79. Nagasaki University, Faculty of Medicine, Nagasaki, Japan, Aug 2011. 11

“Role of 3D Echocardiography in Valvular Heart Disease”

80. Nagasaki Cardiology Society, Nagasaki, Japan, Aug 2011. “Echocardiography and Valvular Heart Disease”

81. Annual Scientific Meeting of Korean Society of Cardiology, Daejeon, South Korea, Dec 2011 “Catheter Proceduers (TAVI and MitraClip) for Valvular Heart Disease and Echocardiography” “Role of Modern 3D Echocardiography in Clinical Cardiology”

82. Tokyo Echo Lab, Tokyo, Japan, Dec 2011. “Clinical Significance of Real-Time 3D Transesophageal Echocardiography”

83. Annual Meeting of Japanese Society of Pediatric Interventional Cardiology, Akita, Japan, Jan 2012. “Current and future view of educational system to catheter diagnosis and management.” “Role of Echocardiography in the

84. Cardiovascular Grand Rounds, Kitasato School of Medicine, Kanagawa, Japan, Jan 2012. “Echocardiographic Guidance of Therapeutic Approach for Valvular Heart Disease”

85. Annual Scientific Meeting of Japanese Circulation Society, Fukuoka, Japan, March 2012. “Clinical Value of 3D Echocardiography” “Role of Echocardiography in Percutaneous Device Procedure”

86. Annual Scientific Meeting of American Heart Association, Los Angeles, CA, Nov 2012. “New Clinical Insights into Echocardiographic Evaluation of Diastolic Function”

87. Tokyo Echo Lab, Tokyo, Japan, Dec 2012. “Echocardiographic Guidance of Therapeutic Approach for Valvular Heart Disease”

88. Annual Meeting of Japanese Circulation Society, Yokohama, Japan, March 2013. “Role of Cardiac Imaging in Transcatheter Therapy for Valvular Disease” “Collaboration among cardiologists, interventionists and surgeon”

89. University of Tokyo, Faculty of Medicine, Japan, March 2013. “Role of Echocardiography in Percutaneous Device Procedure”

90. St.Marianna Medical College, Japan, March 2013. “Echocardiographic Guidance of Therapeutic Approach for Valvular Heart Disease” 12

91. Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Japan, March 2013. “Role of Cardiac Imaging in Transcatheter Therapy for Valvular Disease”

92. Keio University, Faculty of Medicine, Tokyo, Japan, March 2013. “Echocardiographic Guidance of Therapeutic Approach for Valvular Heart Disease”

93. American Society of Echocardiography, Minneapolis, June 2013. “The Right Heart: How Best to Assess?”

94. Cardiac Imaging Grand Rounds at Mayo Clinic, Rochester, July 2013. “Clinical Applications of 3D Echocardiography”

95. Heart Institute Grand Rounds at Cedars-Sinai, Los Angeles, September 2013. “Echocardiographic Evaluation of Right Ventricular Function”

95. Grand Rounds at Columbia University, New York, October 2013. “Clinical Value of 3D Echocardiography”

96. Korean Society of Echocardiography, Incheon, Korea, November 2013. “Hemodynamic Evaluation by Echocardiography” (ASE and KSE Joint Symposium)

97. Japanese Society for Disease, Tokyo, Japan, November 2013 “Diagnosis of by Echocardiography” “Aortic Repair (Bicuspid, Tricuspid AR)”

98. Asian-Pacific Association of Echocardiography, Beijing, China, December 2013. “Role of 3D Echocardiography in Evaluation of Cardiac Function”

99. Annual Conference of Tokyo Heart Lab, Tokyo, Japan, December 2013 “TAVR update” “How to manage the patients with aortic valve disease” “Decision making: TAVI or AVR, Valve in value”

100. Mayo Clinic, April, 2014. “Echocardiographic Evaluation of Right Ventricular Function”

101. Kobe Echo, Scientific Session of Japanese Society of Echocardiography, Japan, July 2014. Commentator for a session on Structural Heart Disease “Echocardiography for Tricuspid Valve Disease” “Echocardiography and MitraClip”

102. Okayama University, Faculty of Medicine, Japan, July 2014 13

“Role of Echocardiography in Valvular Heart Disease”

103. Tokushima University, Faculty of Medicine, Japan, July 2014 “Catheter -based Management of Valvular Heart Disease”

104. American Heart Association, Chicago, Illinois, November 16, 2014. “How to Use Imaging to Guide Paravalvular Device Closure”

TEACHING ACTIVITIES

1. Cardiology Consult Services (2 months per year) 2. Echo-overreading Sessions in the Cardiac Noninvasive Laboratory (4 hour sessions 2 times per week). Teaching echocardiography to medical students, residents, fellows and sonographers 3. Fellows Cardiology Conference (1 time per week) 4. Philips 3D Ultrasound Course (6 times per year)

PUBLICATIONS: ORIGINAL PEER-REVIEWED MANUSCRIPTS

* denotes Japanese publications (1-12). ** denotes Shiota MD as a corresponding author.

1. *Ezaki H, Sakai M, Matsushita S, Shiota T, Ohkawa S, Ueda K, Kuramoto K, Fujii M, Honda T, Kimata S, Hirosawa K, Endo M, Koyanagi H: A successful early surgical repair of ventricular septal perforation after acute myocardial infarction in an 80-year old woman. Kan 1986;3:111-115.

2. *Shiota T, Sakamoto T, Hada Y, Amano K, Takenaka K, Hasegawa I, Suzuki J, Takahashi H, Sugimoto K: Aortic regurgitation in hypertrophic cardiomyopathy detected by color Doppler echocardiography. J Cardiol 1987:17:759-768.

3. *Suzuki J, Sakamoto T, Kawakubo K, Hada Y, Amano K, Takenaka K, Hasegawa I, Shiota T, Sugimoto K, Nishikawa J: Left ventricular short-axis plane for magnetic resonance imaging: Its clinical importance and applications. J Cardiol 1987;17:249- 258.

4. *Suzuki J, Sakamoto T, Takenaka K, Amano K, Hasegawa I, Shiota T, Amano W, Kawakubo K, Sugimoto T, Nishikawa J: Distribution patterns of hypertrophy at the apical level in patients with giant negative T waves: Identification of magnetic resonance imaging. J Cardiogr 1988:18:673-682.

5. *Takahashi H, Sakamoto T, Hada Y, Amano K, Takenaka K, Hasegawa I, Suzuki J, Shiota T, Furuse A, Sugimoto K: Mitral valve prolapse in patients with post- 14

operative atrial septal defect: A preliminary report. J Cardiol 1988:18 (suppl XVIII):107-110.

6. *Miwa A, Shiota T, Ueda K, Igarashi S, Hou-E, Suzuki Y, Fijimori N, Fujisawa A: Comparison of direct effect of isosorbide dinitrate on dilatation of peripheral vessels between in patients with congestive heart failure and without heart failure. Shinzou (Heart) 1988;20:541-547.

7. *Shiota T, Takenaka K, Sakamoto T, Amano K, Suzuki J, Amano W, Takahashi H, Sugimoto K: Antiarrhythmic action of beta-blocking agent in patients with mitral valve prolapse having premature ventricular contractions. J Cardiol 1989;19 (suppl XXI):65-74.

8. *Shiota T, Sakamoto T, Hada Y, Takenaka K, Amano K, Hasegawa I, Suzuki J, Takahashi H, Sugimoto K: Prevalence of mitral valve prolapse in patients with premature ventricular contractions and the relationship between the prolapse and the types of premature contractions. J Cardiol 1989;19:499-504.

9. *Takahashi H, Sakamoto T, Hada Y, Amano K, Takenaka K, Hasegawa I, Suzuki J, Shiota T, Sugimoto T, Furuse A: Mitral valve prolapse in patients with surgically- closed atrial septal defect. J Cardiol 1989;19:893-900.

10. *Shiota T, Sakamoto T, Amano K, Takenaka K, Hasegawa I, Suzuki J, Takahashi H, Saito Y, Sugimoto K: Venous hum and innominate vein flow velocity in chronic anemia: A pulsed Doppler echocardiographic study. J Cardiol 1989;19:885-892.

11. *Amano K, Takenaka K, Sakamoto T, Suzuki J, Shiota T, Igarashi T, Sugimoto T: Usefulness of transesophageal echocardiography in thoracic aortic disease: Comparison with computed tomography and angiography. J Cardiol 1991;21(suppl XXVI);45-56.

12. *Shiota T, Takenaka K, Sakamoto T, Amano W, Igarashi T, Amano K, Sugimoto T, Otake T: Transmitral flow pattern during low-level exercise in ischemic heart disease: A Doppler echocardiographic study. J Cardiol 1993, 23:1-7.

13. Sakamoto T, Takenaka K, Amano K, Hasegawa I, Suzuki J, Shiota T, Takahashi H, Igarashi T: Pharmacodynamic Echocardiography. Echocardiogr 1989:6:131-136.

14. Takenaka K, Shiota T, Sakamoto T, Sakamoto T, Hasegawa I, Amano W, Sugimoto K: Effect of acute systemic blood pressure elevation on left ventricular filling with and without mitral regurgitation. Am J Cardiol 1989;63:623-625.

15. Suzuki J, Sakamoto T, Takenaka K, Kawakubo K, Amano K, Takahashi H, Hasegawa I, Shiota T, Hada Y, Sugimoto T, Nishikawa J: Assessment of the 15

thickness of the right ventricular free wall by magnetic resonance imaging in patients with hypertrophic cardiomyopathy. Br Heart J 1988:60:440-445.

16. Shiota T, Sakamoto T, Takenaka K, Amano K, Hada Y, Hasegawa I, Suzuki J, Takahashi H, Sugimoto K: Aortic regurgitation associated with hypertrophic cardiomyopathy: A color Doppler echocardiographic study. Br Heart J 1989;62:171- 176.

17. Hasegawa I, Sakamoto T, Hada Y, Takenaka K, Amano K, Takahashi H, Takahashi T, Suzuki J, Shiota T, Sugimoto K: Relationship between mitral regurgitation and left ventricular outflow obstruction in hypertrophic cardiomyopathy. J Am Soc Echocardiogr 1989;2:177-186.

18. Takenaka K, Amano W, Sakamoto T, Suzuki J, Shiota T, Sugimoto T: Transesophageal two-dimensional and Doppler echocardiography: Ten representative views. Am J Novinvas Cardiol 1989;3:18-21.

19. You-Bing D, Takenaka K, Sakamoto T, Hada Y, Suzuki J, Shiota T, Amano W, Igarashi T, Amano K, Takahashi H, Sugimoto T: Follow-up in mitral valve prolapse by phonocardiography, M-mode and two-dimensional echocardiography and Doppler echocardiography. Am J Cardiol 1990;65:349-354

20. Suzuki J, Usui M, Takenaka K, Amano K, Takahashi H, Hasegawa I, Shiota T, Amano W, Igarashi T, Sakamoto T, Sugimoto T, Nishikawa J: Cardiac magnetic resonance imaging in evaluation of anatomical structure and function of the ventricles. Jpn Circ J 1990;54:283-287.

21. Takenaka K, Sakamoto T, Shiota T, Amano W, Igarashi T, Sugimoto T: Diagnosis of patent ductus arteriosus in adults by biplane transesophageal color Doppler flow mapping. Am J Cardiol 1991;68:691-693.

22. Shandas R, Gharib M, Liepmann D, Shiota T, Sahn DJ. Experimental studies to define the geometry of the flow convergence region: Laser Doppler particle tracing and color Doppler imaging. Echocardiogr 1992;9:1;43-50.

23. Matsushita S, Hagiwara K, Shiota T, Shimada H, Kuramoto K, Toyokura Y: Lifetime data analysis of disease and aging by the Weibull probability distribution. J Clin Epidemiol 1992;45:10;1165-1175.

24. Rothman A, Ricou F, Weintraub RG, Crowley R, Shiota T, Zhang J, Sahn DJ. Intraluminal ultrasound imaging through a balloon dilation catheter in an animal model of coarctation of the : Circulation 1992; 85:6;2291-2295.

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25. Weintraub R, Shiota T, Elkadi T, Golebiovski P, Zhang J, Rothman A, Ritter SB, Sahn DJ. Transesophageal echocardiography in infants and children with congenital heart disease. Circulation 1992:86:3;711-722.

26. Deng YB, Wang XF, Wang JE, Li ZA, Shiota T, Sahn DJ. Determination of most appropriate Nyquist velocity for applying hemispherical flow convergence equation to calculate flow rate using the transorifice pressure gradient: Digital computer analysis of Doppler color flow convergence region. J Tongji Med Univ 1993, 13(3):143-50.

27. Zhang J, Jones M, Shandas R, Valdes-Cruz LM, Murillo A, Yamada I, Kang SU, Weintraub RG, Shiota T, Sahn DJ. Accuracy of flow convergence estimates of mitral regurgitant rates obtained by using multiple color flow Doppler M-mode aliasing boundaries: An experimental animal study: Am Heart J 1993:125:2;449- 458.

28. Zhang J, Shiota T, Shandas R, Deng YB, Weintraub R, Paik J, Liepmann D, Sahn DJ. Effects of different shaped adjacent surfaces or differing shapes on regurgitant jet sizes: An in vitro study using color Doppler imaging and laser-induced fluorescent dye visualization. J Am Coll Cardiol 1993:22:1522-1592.

29. Deng YB, Shiota T, Shandas R, Zhang J, Sahn DJ. Determination of most appropriate velocity threshold for applying hemispherical flow convergence equation to calculate flow rate according to the transorifice pressure gradient: Digital computer analysis of Doppler color flow convergence region. Circulation 1993:88:1699-1708.

30. Shiota T, Sakamoto T, Takenaka K, Amano K, Amano W, Igarashi T, Otaka T, Sugimoto T: Pseudonormalization of transmitral flow pattern during exercise thallium-201 imaging in patients with : A Doppler echocardiographic study. J Cardiol 1993;23 (Suppl XXXVII):35-42.

31. Watanabe F, Takenaka K, Suzuki J, Amano W, Shiota T, Igarashi T, Aoki T, Sonoda M, Wang Y, Sakamoto T, Sugimoto T: Visualization of sinus venosus-type atrial septal defect by biplane tranesophageal echocardiography. J Am Soc Echocardiogr 1994;7;2:179-181.

32. Chu Tee SD, Shiota T, Weintraub R, Teien DE, Deng YB, Sahn DJ. Evaluation of ventricular septal defect by transesophageal echocardiography: Intraoperative assessment. Am Heart J 1994;127:585-92.

33. Toro L, Weintraub RG, Shiota T, Sahn DJ, Sahn C, McDonald RW, Rice MJ, Hagen-Ansert S: Relation between persistent atrial and redundant septum primum flap (atrial septal ) in fetuses. Am J Cardiol 1994:73;711- 713. 17

34. Shiota T, Teien D, Deng YB, Ge S, Shandas R, Holcomb, S, Sahn DJ. Estimation of regurgitant flow volume based on centerline velocity/distance profiles using digital color M-Q Doppler: Applied to orifices of different shapes. J Am Coll Cardiol 1994:24:440-445.

35. Shiota T, Jones M, Teien DE, Yamada I, Passafini A, Sahn DJ, Knudson O, Shandas R: Evaluation of mitral regurgitation using a digitally determined color Doppler flow convergence "centerline" acceleration method: Studies in an animal model with quantified mitral regurgitation. Circulation 1994;89:2879-2887.

36. Shiota T, Jones M, Teien D, Yamada I, Passafini A, Knudson O, Sahn DJ. Color Doppler regurgitant jet area for evaluating eccentric mitral regurgitation: An animal study with quantified mitral regurgitation. J Am Coll Cardiol 1994;24:813-819.

37. Sohn S, Rothman A, Shiota T, Luk G, Tong A, Swensson RE, Sahn DJ. Acute and follow-up intravascular ultrasound findings following balloon dilation of coarctation of the aorta. Circulation 1994;90:340-347.

38. DeGroff CG, Rice MJ, Reller MD, Shiota T, Sahn DJ. Intravascular ultrasound can assist angiographic assessment of coarctation of the aorta. Am Heart J 1994;128:836-839.

39. Teien DE, Jones M, Shiota T, Yamada I, Sahn DJ. Doppler evaluation of the severity of mitral regurgitation: Relationship to pulmonary venous blood flow patterns in an animal study. J Am Coll Cardiol 1995;25:264-8.

40. Tong AD, Rothman A, Atkinson RL, Shiota T, Ricou F, Sahn DJ. Intravascular ultrasound imaging of coarctation of the aorta: Animal and human studies. Am J Cardiol Imag 1995;9(4):250-6.

41. Saeian K, Weintraub R, Hagen-Ansert S, Sahn C, Shiota T, Kenny A, Sahn, DJ. Increased fetal activity and heart rate during and immediately after pulsed Doppler echocardiography. Echocardiogr 1995;12:71-77.

42. Shiota T, Jones M, Valdes-Cruz LM, Shandas R, Yamada I, Sahn DJ. Transmitral flow and mitral orifice area: An in vivo experimental evaluation of the proximal flow convergence method. Am Heart J 1995;129:114-123.

43. Mizushige K, Shiota T, Paik J, Griever G, Depp MR, Passafini A, Shandas R, DeMaria AN, Sahn DJ. Effects of pulmonary venous flow direction on mitral regurgitation jet area as imaged by color Doppler flow mapping: An in vitro study. Circulation 1995;91:1834-1839.

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44. Teien D, Jones M, Shiota T, Yamada I, Sahn DJ. Relation of left atrial V-wave/left ventricular systolic pressure ratio to mitral regurgitant volume. Am Heart J 1995;129:282-284.

45. Tong AD, Rothman A, Shiota T, Rice M, Hellenbrand W, Sahn DJ. Interventional of patients with congenital heart disease under transesophageal echocardiographic guidance. Am Heart J 1995;129:827-831.

46. Ge S, Shiota T, Rice MJ, Hellenbrand WE, Sahn DJ. Transesophageal ultrasound imaging during stent implantation to relieve superior vena cava to intra-atrial baffle obstruction following Mustard repair of transposition of the great arteries. Circulation 1995;91:2679-80.

47. Passafini A, Shiota T, Depp M, Paik J, Ge S, Mizushige K, Shandas R, DeMaria AN, Sahn DJ. Factors influencing on pulmonary venous flow velocity patterns in mitral regurgitation: An in vitro study. J Am Coll Cardiol 1995;26:1333-9.

48. Shiota T, Jones M, Teien DE, Yamada I, Passafini A, Ge S, Sahn DJ. Dynamic change in mitral regurgitant orifice area: Comparison of color Doppler echocardiographic and electromagnetic flowmeter-based methods in a chronic animal model. J Am Coll Cardiol 1995;26:528-36.

49. Silberbach M, Woods LL, Hohimer AR, Shiota T, Matsuda Y, Davis LE: Role of endogenous atrial natriuretic peptide in chronic anemia in the ovine fetus: Effects of a non-peptide antagonist for atrial natriuretic peptide receptor. Pediatr Res 1995;38:722-728.

50. Shiota T, Jones M, Yamada I, Heinrich RS, Ishii M, Sinclair G, Yoganathan AP, Sahn DJ. Evaluation of aortic regurgitation with digitally determined color Doppler- imaged flow convergence acceleration: A quantitative study in sheep. J Am Coll Cardiol 1996;26:203-210.

51. Simpson AI, Shiota T, Gharib M, Sahn DJ. Current status of flow convergence for clinical applications: Is it a leaning tower of “PISA”? J Am Coll Cardiol 1996;27:504-509.

52. Shiota T, Jones M, Yamada I, Heinrich RS, Ishii M, Sinclair B, Holcomb S, Yoganathan AP, Sahn DJ. Effective regurgitant orifice area by the color Doppler flow convergence method for evaluating the severity of chronic aortic regurgitation: An animal study. Circulation 1996;93:594-602.

53. Xu J, Shiota T, Ge S, Gong Z, Rice MJ, Cobanoglu A, Sahn DJ. Intraoperative transesophageal echocardiography using high-resolution biplane 7.5 MHz probes with continuous-wave Doppler capability in infants and children with tetralogy of Fallot. Am J Cardiol 1996;27:1511-1518. 19

54. Shiota T, Sinclair B, Ishii M, Zhou X, Ge S, Teien DE, Gharib M, Sahn DJ. Three- dimensional reconstruction of color Doppler flow convergence regions and regurgitant jets: An in vitro quantitative study. J Am Coll Cardiol 1996; 77:539-542.

55. Ishii M, Jones M, Shiota T, Heinrich R, Yamada I, Sinclair B, Yoganathan AP, Sahn DJ. Evaluation of eccentric aortic regurgitation by color Doppler jet and color Doppler-imaged vena contracta measurements: An animal study of quantified aortic regurgitation. Am Heart J 1996;132:796-804.

56. Ge S, Jones M, Shiota T, Yamada I, DeGroff CG, Teien DE, Baptiasta AM, Sahn DJ. Quantification of mitral flow by Doppler color flow mapping. J Am Soc Echocardiogr 1996;9:700-709.

57. Grauer SE, Pantely GA, Xu J, Ge S, Giraud GD, Shiota T, Sahn DJ. Myocardial imaging with a new transpulmonary lipid-fluorocarbon echo contrast agent: Experimental studies in pigs. Am Heart J 1996;132: 938-945.

58. Grauer SE, Xu J, Pantely GA, Ge S, Gong Z, Shiota T, Zhou X, Sahn DJ. Aerosomes MRX115, a new echocontrast agent, produces myocardial opacification after intravenous injection in primates: Studies before and after left anterior descending artery occlusion. Academic Radiol 1996;3suppl.2:405-6.

59. Shiota T, Jones M, Ishii M, Yamada I, Sahn DJ. Axial centerline flow convergence and vena contracta methods for evaluation of aortic regurgitation: a chronic animal study. Jpn J Med Ultraso 1996;23:843-853.

60. Piel JE, Lewandowski RS, Lorraine PW, Smith LS, Shiota T, Sahn DJ. 7.5-MHz pediatric phased array transesophageal endoscope. Echocardiogr 1996;13:677-683.

61. Ishii M, Jones M, Shiota T, Yamada I, Heinrich RS, Holcomb SR, Yoganathan AP, Sahn DJ. Quantifying aortic regurgitation using the color Doppler-imaged vena contracta: A chronic animal model study. Circulation 1997;96:2009-2015.

62. Harada K, Rice MJ, Shiota T, Ishii M, McDonald RW, Reller MD, Sahn DJ. Gestational age and growth-related alterations in fetal right and left ventricular diastolic filling patterns. Am J Cardiol 1997;79:173-177.

63. Harada K, Rice MJ, McDonald RW, Shiota T, Ishii M, Reller MD, Sahn DJ. Doppler echocardiographic evaluation of ventricular diastolic filling in fetuses with ductal construction. Am J Cardiol 1997;79:442-446.

64. Harada K, Rice MJ, Shiota T, McDonald RW, Reller MD, Sahn DJ. Two- dimensional echocardiographic evaluation of ventricular systolic function in human fetuses with ductal constriction. Ultrasound Obstet Gynecol 1997;10(4):247-253. 20

65. Harada K, Reller MD, Shiota T, Marcella CP, Sahn DJ. Echocardiographic indexes of rejection in pediatric cardiac transplant recipients managed without maintenance steroid immunosuppression. Am J Cardiol 1997;79:693-6.

66. Stock JH, Reller MD, Sharma S, Pavcnik D, Shiota T, Sahn DJ. Trans-balloon intravascular ultrasound imaging during balloon angioplasty in animal models with coarctation and branch pulmonary stenosis. Circulation 1997;95:2354-7.

67. Duwelius P, Huckfeldt R, Mullins RJ, Shiota T, Lindsey T, Woll TS, Lindsey KH, Wheeler D: The effects of femoral intramedullary reaming on pulmonary function in a sheep lung model. J Bone Joint Surg 1997;79-A:194-202.

68. Xu J, Shiota T, Omoto R, Zhou X, Kyo S, Ishii M, Rice MJ, Sahn DJ. Intravascular ultrasound assessment of regional aortic wall stiffness, distensibility, and compliance in patients with coarctation of the aorta. Am Heart J 1997;134:93-98.

69. Shiota T, Jones M, Aida S, Tsujino H, Yamada I, Delabays A, Pandian NG, Sahn DJ. Calculation of aortic regurgitant volume by a new digital Doppler color flow mapping method: an animal study with quantified chronic aortic regurgitation. J Am Coll Cardiol 1997;30:834-42.

70. Shiota T, Jones M, Delabays A, Li X, Yamada I, Ishii M, Acar P, Holcomb S, Pandian NG, Sahn DJ. Direct measurement of three-dimensionally reconstructed flow convergence surface area and regurgitant flow in aortic regurgitation: in vitro and chronic animal studies. Circulation 1997;96:3687-3695.

71. Zhou X, Jones M, Shiota T, Yamada I, Teien D, Sahn DJ. Vena contracts imaged by Doppler color flow mapping predicts the severity of eccentric mitral regurgitation better than color jet area: A chronic animal study. J Am Coll Cardiol 1997;30:1393- 1398.

72. Shiota T, Omoto R, Cobanoglu A, Kyo S, Rice MJ, Sandhu SK, Smith LS, Sahn DJ. Usefulness of transesophageal imaging of flow convergence region in the operating room for evaluating isolated patent ductus arteriosus. Am J Cardiol 1997;80:1108- 1112.

73. Teien DE, Jones M, Shiota T, Yamada I, Frithiof D, Sahn DJ. Left ventricular stroke work in mitral regurgitation: an animal experimental study. J Heart Valve Disease 1997;6:613-620.

74. Chikada M, Shiota T, Aida S, Yamada I, Sahn MD, Jones M: A method for estimating aortic regurgitant effective orifice area by digital Doppler color flow mapping. J Heart Valve Disease 1998;7:102-107.

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75. Ishii M, Jones M, Shiota T, Yamada I, Heinrich RS, Holcomb SR, El-Kadi T, MD, Yoganathan AP, Sahn DJ. What is the validity of continuous wave Doppler grading of aortic regurgitation severity? A chronic animal model study. J Am Soc Echocardiogr 1998;11:332-337.

76. Singh G, Shiota T, Sandhu S, Cobanoglu A, Droukas P, Rice MJ, Sahn DJ. Diagnostic accuracy and role of intraoperative biplane transesophageal echocardiography in pediatric patients with left ventricle outflow tract lesions. J Am Soc Echocardiogr 1998;11:47-56.

77. Pantely GA, Joyce M, Grauer SE, Giraud GD, Shiota T, Sahn D: Phase II, placebo- controlled trial of MRX115 (Aerosomes) for left heart and myocardial perfusion imaging. Academic Radiology 1998;5 Suppl 1:S66-8.

78. Shiota T, Jones M, Chikada M, Fleishman CE, Castellucci JB, Cotter B, DeMaria AN, von Ramm OT, Kisslo J, Ryan T, Sahn DJ. Real-time three-dimensional echocardiography for determining right ventricular stroke volume in an animal model of chronic right ventricular volume overload. Circulation 1998;97:1897-1900.

79. Aida S, Shiota T, Tsujino H, Sahn DJ. Quantification of aortic regurgitant volumes by a newly developed automated cardiac flow measurement method: an in vitro study. J Am Soc Echocardiogr 1998;11:874-881.

80. Ishii M, Jones M, Shiota T, Sahn DJ. Temporal variability of vena contracta and jet areas using color Doppler in aortic regurgitation: A chronic animal model study. J Am Soc Echocardiogr 1998;11:1064-1071.

81. Qin JX, Jones M, Shiota T, Greenberg NL, Cardon LA, Zetts AD, Tsujino H, Thomas JD. Comparison of left ventricular stroke volume determination by real- time three-dimensional echocardiography and conventional two-dimensional echocardiography: An animal study during non ischemic and ischemic conditions. Computers in Cardiology 1998;25:645-648.

82. Shiota T, Lewandowski R, Piel JE, Smith LS, Lancee C, Djoa K, Bom N, Cobanoglu A, Rice MJ, Sahn DJ. A micro-multiplane transesophageal echocardiography probe for intra-operative study of congenital heart disease repairs in neonates, infants, children and adults. Am J Cardiol 1999;83:292-295.

83. Mori Y, Shiota T, Jones M, Wanitkun S, Irvine T, Li X, Delabays A, Pandian NG, Sahn DJ. Three-dimensional reconstruction of the color Doppler-imaged vena contracta for quantifying aortic regurgitation: studies in a chronic animal model. Circulation 1999;99:1611-1617.

84. Acar P, Jones M., Shiota T, Masani N, Delabays A, Yamada I, Sahn DJ, Pandian NG: Quantitative assessment of chronic aortic regurgitation with 3-dimensional 22

echocardiographic reconstruction: comparison with electromagnetic flowmeter measurements. J Am Soc Echocardiogr 1999;12:138-148.

85. Shiota T, Jones M, Agler DA, McDonald R, Marcella C, Qin JX, Zetts DA, Greenberg NL, Cardon LA, Sun JP, Sahn DJ, Thomas JD. New echocardiographic windows for quantitative determination of aortic regurgitant volume using the color Doppler flow convergence and vena vontracta: experimental and clinical studies. Am J Cardiol 1999;83:1064-1068.

86. Wanitkun S, Gharib M, Zarandi M, Shiota T, Sahn DJ. Evaluation of descending aortic flow volumes and effective orifice area through aortic coarctataion by spatiotemporal integration of color Doppler data: an in vitro study. J Am Soc Echocardiogr 1999;12:517-526.

87. Harada K, Tsuda A, Rice MJ, Shiota T, McDonald RW, Sahn DJ. Relation of atrial size and function to Doppler indexes of diastolic function in normal human fetuses. Am J Cardiol 1999;83(9):1405-8.

88. Shiota T, Jones M, Aida S, Chikada M, Tsujino H, El-kai, T, Sahn DJ. Validation of the accuracy of both right and left ventricular outflow volume determinations and semiautomated calculation of shunt volumes through atrial septal defects by digital color Doppler flow mapping in a chronic animal model. J Am Coll Cardiol 1999;34:587-593.

89. Irvine T, Wanitkun S, Powers J, Shiota T, Kenny A, Sahn DJ. Acoustically stimulated transient power scattering explains enhanced detection of the very low velocities in myocardial capillaries by power Doppler imaging: an in vitro study. J Am Soc Echocardiogr 1999;12(8):643-649.

90. Li X, Shiota T, Delabays A, Teien, D, Zhou X, Sinclair B, Pandian NG, Sahn DJ. Flow convergence flow rates from three-dimensional reconstruction of color Doppler flow maps for computing transvalvular regurgitant flow without geometric assumptions: An in vitro quantitative flow study. J Am Soc Echocardiogr 1999;12:1035-1044.

91. **Shiota T, McCarthy PM, White RD, Qin JX, Greenberg NL, Flamm SD, Wong J, Thomas JD. Initial clinical experience of real-time 3-dimensional echocardiography in patients with ischemic and idiopathic dilated cardiomyopathy. Am J Cardiol 1999;84:1068-1073.

92. Tsujino H, Jones M, Shiota T, Qin JX, Cardon LA, Morehead AJ, Travaglini A, Bauer F, Zetts AD, Greenberg NL, Panza JA, Thomas JD. Estimation of the spatial mean and peak flow velocities using real-time 3D color Doppler echocardiography. Computers in Cardiology 1999; 173-176

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93. Morehead AJ, Firstenberg MS, Shiota T, Qin JX, Armstrong G, Cosgrove DM, Thomas JD. Paravalvular regurgitation after as detected by intra- operative color Doppler: The role of systemic anticoagulation. Ann Thorac Surg 2000;69(1):135-139.

94. Gillinov MA, Cosgrove DM, Shiota T, Qin J, Tsujino H, Stewart WJ, Thomas JD, Porqueddu M, Blackstone EH: The Cosgrove-Edward annuloplasty system preserves mitral annular flexibility and function at 5 years. Ann Thorac Surg 2000;69(3):717- 21.

95. **Qin JX, Shiota T, Thomas JD. Determination of left ventricular volume, ejection fraction and myocardial mass by real-time three-dimensional echocardiography. Echocardiogr 2000;17(8):781-786.

96. Yalcin F, Shiota T, Odabashian J, Agler D, Greenberg NL, , Garcia MJ, Lever HM, Thomas JD. Comparison by real-time three-dimensional echocardiography of left ventricular geometry in hypertrophic cardiomyopathy versus secondary left ventricular hypertrophy. Am J Cardiol 2000;85:1035-1038.

97. **Qin JX, Jones M, Shiota T, Greenberg NL, Tsujino H, Firstenberg MS, Gupta PC. Zetts AD, Xu Y, Sun JP, Cardon LA, Odabashian JA, Flamm SD, White RD, Panza JA, Thomas JD. Validation of real-time three-dimensional echocardiography for quantifying left ventricular volumes in the presence of a left ventricular aneurysm: in vitro and in vivo studies. J Am Coll Cardiol 2000; 35:900-907.

98. **Qin JX, Shiota T, McCarthy PM, Firstenberg MS, Greenberg NL, Tsujino H, Bauer F, Travaglini A, Hoercher KJ, Buda T, Smedira NG, Thomas JD. Real-time three-dimensional echocardiographic study of left ventricular function after infarct exclusion surgery for ischemic cardiomyopathy. Circulation 2000;102 (suppl III):101-106.

99. **Qin JX, Shiota T, Sun JP, Odabashian JA, White RD, Flamm SD, Thomas JD. A new digital method for estimating left ventricular volume using real-time 3D echocardiography: A comparison with magnetic resonance imaging. J Euro Soc Echocardiogr 2000;1:96-104.

100. Hang X, Greenberg NL, Shiota T, Firstenberg MS, Thomas JD. Compression of real-time volumetric echocardiographic data using modified SPIHT based on the three-dimensional wavelet packet transform. Computers in Cardiology 2000;27:123- 126.

101. Corsi C, Lamberti C, Sarti A, Travaglini A, Shiota T, Thomas JD. Real-time 3D echocardiographic data analysis of left ventricular volume estimation. Computers in Cardiology 2000;27:107-110.

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102. Harada K, Tsuda A, Shiota T, Rice MJ Ishii M, Mcdonald RW, Sahn DJ. Effect of left ventricular wall mass on Doppler filling patterns in the developing normal human heart. Am J Cardiol 2000;86(6):659-663.

103. Tsujino H, Jones M, Shiota T, Qin JX, Cardon LA, Morehead AJ, Zetts AD, Bauer F, Sitges M, Hang X, Greenberg NL, Panza JA, Thomas JD. Impact of temporal resolution on flow quantification by real-time 3D color Doppler echocardiography: Numerical modeling and animal validation study. Computers in Cardiology 2000;27:761-764.

104. Corsi C, Borsari M, Consegnati F, Sarti A, Lamberti C, Travaglini A, Shiota T, Thomas JD. Left ventricular endocardial surface detection based on real-time 3D echocardiographic data. Euro J Ultrasound 2001;13:41-51

105. **Tsujino H, Jones M, Shiota T, Qin JX, Greenberg NL, Cardon LA, Morehead AJ, Zetts AD, Travaglini A, Bauer F, Panza JA, Thomas JD. Real-time three- dimensional color Doppler echocardiography for characterizing the spatial velocity distribution and quantifying the peak flow rate in the left ventricular outflow tract. Ultrasound in Med & Biol 2001;27:69-74.

106. Bauer F, Shiota T, Qin JX, White RD, Thomas JD. Mesure des volumes de I’oreillette et du ventricule gauche par echographie 3D en temps reel. Validation par resonance magnetique nucleaire. Arch Mal Coeur Vaiss 2001;94(1):31-8.

107. McCarthy PM, Fukamachi K, Takagaki M, Ochiai Y, Young JB, Tabata T, Shiota T, Qin JX, Thomas JD, Mortier TJ, Schroeder RF, Schweich C: Device based left ventricular shape change: A new concept for the treatment of dilated cardiomyopathy. J Thorac Cardiovasc Surg 2001;122(3):482-90.

108. **Sitges M, Jones M, Shiota T, Prior DL Qin JX, Tsujino H, Bauer F, Kim YJ, Deserrano D, Greenberg NL, Cardon LA, Zetts AD, Gracia MJ, Thomas JT. Interaliasing distance of the flow convergence surface for determining mitral regurgitant volume: A validation study in a chronic animal model. J Am Coll Cardiol 2001;38(4):1195-202.

109. Bauer F, Shiota T, Thomas JD. Real time 3D Echocardiography. Arch Mal Coeur Vaiss. 2001;94(7):690-5.

110. **Qin JX, Shiota T, Lever HM, Sitges M, Rubin DN, Bauer F, Tsujino H, Drinko JK, Martin M, Tuzcu EM, Smedira NG, Lytle B, Thomas JD. Outcome of patients with hypertrophic obstructive cardiomyopathy after percutaneous transluminal septal myocardial ablation and surgery. J Am Coll Cardiol 2001;38:1994- 2000.

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111. Corsi C, Larnberti C, Sarti A, Saracino G, Shiota T, Thomas JD. A semi-automatic method for left ventricle volume estimate: an in vivo validation study. Computers in Cardiology 2001;28:109-112.

112. **Qin JX, Shiota T, Lever HM, Rubin DN, Bauer F, Tsujino H, Sitges M, Greenberg NL, Drinko JK, Martin M, Agler DA, Thomas JD. Impact of left ventricular outflow tract area on systolic outflow velocity in hypertrophic cardiomyopathy: a real-time 3-D echocardiographic study. J Am Coll Cardiol 2002;39:308-314.

113. **Shiota T, Jones M, Tsujino H, Qin JX, Zetts AD, Greenberg NL, Cardon LA, Panza JA Thomas JD. Quantitative analysis of aortic regurgitation: real-time 3D and 2D color Doppler echocardiographic method: A clinical and a chronic animal study. J Am Soc Echocardiogr 2002;15:966-971.

114. **Shiota T. Automated cardiac flow measurement by digital doppler echocardiography: Echocardiographic quantification of stroke volume, regurgitant and shunt flow volume. Heart 2002;88:211-212.

115. Takagaki M, McCarthy PM, Dessoffy R, Ochiai Y, Doi K, Howard M, Qin J, Yang H, Shiota T, Connor J, Fukamachi K. Device-based left ventricular shape change: Validation of conductance technology in shape-changed . ASAIO 2002;48:268-271.

116. **Shiota T, McCarthy PM. Volume reduction surgery for end-stage ischemic heart disease. Echocardiogr 2002;19:605-612.

117. Wang K, Zhou X, Zhou Z, Tarakji K, Qin JX, Sitges M, Shiota T, Forudi F, Schaub RG, Kumar A, Penn MS, Topol EJ, Lincoff M. Recombinant Soluble P-Selectin Glycoprotein Ligand-Ig (rPSGL-Ig) Attenuates Infarct Size and Myoloperoxidase Activity in a Canine Model of Ischemia-Reperfusion. Thrombosis and Haemostasis 2002;88:149-154.

118. Yang, H, Jones M, Shiota T, Qin JX, Kim YJ, Popovic Z, Pu M, Greenberg NL, Cardon LA, Eto Y, Sitges M, Zetts AD, Thomas JD. Pulmonary venous flow determinants of left atrial pressure under different loading conditions in a chronic animal model with mitral regurgitation. J Am Soc Echocardiogr 2002;15:1181-1188.

119. **Kim YJ, Jones M, Shiota T, Tsujino H, Qin JX, Bauer F, Sitges M, Kwan J, Cardon LA, Zetts AD, Thomas JD. Effect of load alterations on the effective regurgitant orifice area in chronic aortic regurgitation. Heart 2002;88:397-400.

120. **Bauer F, Jones M, Shiota T, Firstenberg MS, Qin JX, Tsujino H, Kim YJ, Sitges M, Cardon LA, Zetts AD, Thomas JD. Left ventricular outflow tract mean systolic

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acceleration as a surrogate for the slope of the left ventricular end-systolic pressure- volume relationship. J Am Coll Cardiol 2002;40:1320-1327.

121. Saracino G, Greenberg NL, Shiota T, Corsi C, Lamberti C, Thomas JD. Fast interactive real-time volume rendering of real-time three-dimensional echocardiography: An implementation for low-end computers. Computers in Cardiol 2002;29:613-6.

122. **Sitges M, Jones M, Shiota T, Qin JX, Tsujino T, Bauer F, Kim YJ, Agler DA, Cardon LA, Zetts AD, Panza JA, Thomas JD. Real-time Three-dimensional Color- Doppler Evaluation of the Flow Convergence Zone for Quantification of Mitral Regurgitation: Validation Experimental Animal Study and Initial Clinical Experience. J Am Soc Echocardiogr 2003;16:38-45.

123. **Kwan J, Shiota T, Agler DA, Popovic ZB, Qin JM, Gillinov AM, Steward WJ, Cosgrove, DM, McCarthy PM, Thomas JD. Geometric differences of the mitral apparatus between ischemic and delated cardiomyopathy with significant mitral regurgitaion: real-time 3D echocardiography study. Circulation 2003;107:1135-1140.

124. **Sitges M, Shiota T, Lever HM, Qin JX, Bauer F, Drinko JK, Agler DA, Martin MG, Greenberg, NL, Smedira NG, Lytle, BW, Tuzcu EM, Garcia MJ, Thomas JD. Improved left ventricular diastolic function after septal reduction in hypertrophic obstructive cardiomyopathy: a follow-up study in patients undergoing percutaneous septal alcohol ablation or surgical myotomy/myectomy. Am J Cardiol 2003;91,817- 821.

125. **Qin JX, Shiota T, McCarthy PM, Asher CR, Hail M, Agler DA, Popovic ZB, Greenberg NL, Smedira NG, Starling RC, Young JB, Thomas JD. Importance of associated with left ventricular reconstruction for patients with ischemic cardiomyopathy: a real-time three-dimensional echocardiographic study. Circulation 2003;108:11-241-11-246.

126. Nash PG, Agler DA, Shin JF, Qin JX, Smedira NG, Lever HM, Shiota T, Thomas JD. Epicardial real time 3D echocardiography during septal myectomy for obstructive hypertrophic cardiomyopathy. Circulation 2003;108:e54-55.

127. **Shin JH, Shiota T, Kim YJ, Kwan J, Qin JX, Eto Y, Rodriguez LL, Thomas JD. False-positive exercise echocardiograms: Impact of gender and blood pressure response. Am Heart J 2003;146:914-9.

128. Yang H, Sun JP, Lever HM, Popovic ZB, Drinko JK, Greenberg NL, Shiota T, Thomas JD, Garcia MJ. Use of strain imaging in detecting segmental dysfunction in patients with hypertrophic cardiomyopathy. J Am Soc Echocardiogr 2003 Mar;16(3):233-239.

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129. Qin JX, Shiota T, Lever HM, Asher CR, Greenberg NL, Agler DA, Drinko JK, Schnauffer MJ, Smedira NG, Tuzcu EM, Lytle BW, Thomas JD. Conduction system abnormalities in patients with hypertrophic obstructive cardiomyopathy following septal reduction interventions. Am J Cardiol 2004;93:171-175.

130. **Qin JX, Shiota T, Asher CR, Smedira NG, Shin JH, Agler DA, Nash JP, Greenberg NL, Lever HM, Lytle BW, Thomas JD. Usefulness of real-time 3- dimensional echocardiography for evaluation of myectomy in patients with hypertrophic cardiomyopathy. Am J Cardiol 2004;94:964-966.

131. **Bauer F, Shiota T, White RD, Lever HM, Qin JX, Drinko J, Martin M, Tsujino H, Sitges M, Kim YJ, Thomas JD. Determinant of left atrial dilation in patients with hypertrophic cardiomyopathy: A real-time 3-dimensional echocardiographic study. J Am Soc Echocardiogr 2004; 17(9):968-75.

132. Popovic ZB, Saracino G, Deserranno D, Yang H, Greenberg NL, Takagaki M, Fukamachi K, Ochiai Y, Inoue M, Schenk S, Doi K, Qin JX, McCarthy PM, Shiota T, Thomas JD. Echocardiographic assessment of regional ventricular function after device-based change of left ventricular shape. J Am Soc Echocardiogr 2004;17(5):411-417.

133. **Kwan J, Qin JX, Popovic ZB, Agler DA, Thomas JD, Shiota T. Geometric changes of mitral annulus assessed by real-time 3-dimensional echocardiography: Becoming enlarged and less nonplanar in the anteroposterior direction during in proportion to global left ventricular systolic function. J Am Soc Echocardiogr 2004;17(11):1179-1184.

134. **Tsujino H, Jones M, Qin JX, Sitges M, Cardon LA, Morehead AJ, Zetts AD, Bauer F, Kim YJ, Hang XY, Greenberg NL, Thomas JD, Shiota T. Combination of pulsed-wave Doppler and real-time three dimensional color doppler echocardiography for quantifying the stroke volume in the left ventricular outflow tract. Ultrasound in Medicine & Biology 2004;30: 1441-1446.

135. McGee EC, Gillinov AM, Blackstone EH, Rajeswaran J, Cohen G, Naja F, Shiota T, Sabik JF, Lytle BW, McCarthy PM, Cosgrove DM. Recurrent mitral regurgitation after annuloplasty for functional ischemic mitral regurgitation. J Thorac Cardiovasc Surg 2004;128(6):916-24.

136. Gillinov AM, Smedira NG, Shiota T. Use of the alfieri edge-to-edge technique to eliminate left ventricular outflow tract obstruction caused by mitral systolic anterior motion. Ann Thorac Surg 2004;78(6):e92-e93.

137. **Qin JX, Shiota T, Tsujino H, Saracino G, White RD, Greenberg NL, Kwan J, Popovic ZB, Agler DA, Stewart WJ, Thomas JD. Mitral annular motion as a surrogate for left vengricular ejection fraction: Real-time three-dimensional

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echocardiography and magnetic resonance imaging studies. Eur J Echocardiogr 2004;5:407-415.

138. Ahmad RM, Gillinov AM, McCarthy PM, Blackstone EH, Apperson-Hansen C, Qin JX, Agler D, Shiota T, Cosgrove DM. Annular geometry and motion in human ischemic mitral regurgitation: Novel assessment with three-dimensional echocardiography and computer reconstruction. Ann Thorac Surg 2004;78(6):2063- 2068.

139. Saracino G, Daimon M, Greenberg N, Shiota T, Thomas JD. A novel system for the assessment of mitral annular geometry and analysis of 3D motion of the mitral annulus from 3D echocardiography. Comput Cardio 2004;31:69-72.

140. **Fukuda S, Song JM, Gillinov AM, McCarthy PM, Daimon M, Kongsaerepong V, Thomas JD, Shiota T. Tricuspid valve tethering predicts residual tricuspid regurgitation after tricuspid annuloplasty. Circulation 2005;111(8): 975-979

141. **Eto Y, Yamada H, Shin JH, Agler DA, Tsujino H, Qin JX, Saracino G, Greenberg NL, Thomas JD, Shiota T. Automated mitral annular tracking: A novel method for evaluating mitral annular motion using 2-Dimensional echocardiography. J Am Soc Echocardiogr 2005;18(4): 306-12.

142. **Daimon M, Shiota T, Liddicoat JR, Hayase M, Ruel M, Cohn WE, Blacker SJ, Gillinov MA. Percutaneous mitral valve repair for chronic ischemic mitral regurgitation: A real-time 3D echocardiographic study in an ovine model. Circulation 2005;111(17): 2183-9.

143. **Sitges M, Qin JX, Lever H, Bauer F, Drinko JK, Agler DA, Kapadia SR, Tuzcu EM, Smedira NG, Lytle BW, Thomas JD, Shiota T. Evaluation of left ventricular outflow tract area after septal reduction in obstructive hypertrophic cardiomyopathy: A real-time three-dimensional echocardiographic study. Am Heart J 2005;150(4): 852-8.

144. **Bauer F, Jones M, Qin JX, Castro P, Asada J, Sitges M, Cardon LA, Tsujino H, Zetts AD, Panza JA, Thomas JD, Shiota T. Quantitative analysis of left atrial function during left ventricular ischemia with and without left atrial ischemia: A real-time 3D echographic study. J Am Soc Echocardiogr 2005;18(8): 795-801.

145. Chikada M, Shiota T, Jones M. Gorlin formulas for aortic regurgitant and mitral regurgitant orifice areas: Experimental studies. J Cardiol 2005;46(4): 149-54.

146. **Qin JX, Jones M, Travaglini A, Song JM, Li J, White RD, Tsujino H, Greenberg NL, Zetts AD, Panza JA, Thomas JD, Shiota T. The accuracy of left ventricular mass determined by real-time three-dimensional echocardiography in chronic animal

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and clinical studies: A comparison with postmortem examination and magnetic resonance imaging. J Am Soc Echocardiogr 2005;18(10): 1037-43.

147. Popovic ZB, Martin M, Fukamachi K, Inoue M, Kwan J, Doi K, Qin JX, Shiota T, Garcia MJ, McCarthy PM, Thomas JD. Mitral annulus size links ventricular dilatation to functional mitral regurgitation. J Am Soc Echocardiogr 2005;18(9): 959-63.

148. Gillinov AM, Blackstone EH, Rajeswaran J, Mawad M, McCarthy PM, Sabik JF, Shiota T, Lytle BW, Cosgrove DM. Ischemic versus degenerative mitral regurgitation: Does etiology affect survival? Ann Thorac Surg 2005;80(3): 311-9 discussion 809.

149. Notomi Y, Lysyansky P, Setser RM, Shiota T, Popovic ZB, Martin-Miklovic MG, Weaver JA, Oryszak SJ, Greenberg NL, White RD, Thomas JD. Measurement of ventricular torsion by two-dimensional ultrasound speckle tracking imaging. J Am Coll Cardiol 2005;45(12): 2034-41.

150. Notomi Y, Setser RM, Shiota T, Martin-Miklovic MG, Weaver JA, Popovic ZB, Yamada H, Greenberg NL, White RD, Thomas JD. Assessment of left ventricular torsional deformation by Doppler tissue imaging: Validation study with tagged magnetic resonance imaging. Circulation 2005;111(9):1141-7.

151. **Shiota T. Clinical application of 3-dimensional echocardiography. J Echocardiogr 2005;3(3):93-103.

152. **Fukuda S, Grimm R, Song JM, Kihara T, Daimon M, Agler DA, Wilkoff BL, Natale A, Thomas JD, Shiota T. Electrical conduction disturbance effects on dynamic changes of functional mitral regurgitation. J Am Coll Cardiol 2005;46(12)2270-6.

153. Notomi Y, Martin-Miklovic MG, Oryszak SJ, Shiota T, Deserranno D, Popovic ZB, Garcia MJ, Greenberg NL, Thomas JD. Enhanced ventricular untwisting during exercise: a mechanistic manifestation of elastic recoil described by Doppler tissue imaging. Circulation 2006;113(21):2524-33.

154. Kwan J, Yeom BW, Jones M, Qin JX, Zetts AD, Thomas JD, Shiota T. Acute geometric changes of the mitral annulus after coronary occlusion: a real-time 3D echocardiography study. J Korean Med Science 2006;21(12):217-23.

155. Notomi Y, Srinath G, Shiota T, Martin-Miklovic MG, Beachler L, Howell K, Oryszak SJ, Deserranno DG, Freed AD, Greenberg NL, Younnoszai A, Thomas JD. Maturational and adaptive modulation of left ventricular torsional biomechanics: Doppler tissue imaging observation from infancy to adulthood. Circulation 2006;113(21):2534-41.

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156. Atik FA, Navia JL, Krishnamurthi V, Singh G, Shiota T, Pitas G, Brizzio ME, Gonzalez- Stawinski GV, Kefer J, Goldfarb D. Solitary massive right ventricular metastasis of renal cell carcinoma without inferior vena cava or right atrium involvement. J Card Surg 2006;21(3):304-6

157. **Fukuda S, Gillinov AM, McCarthy PM, Stewart WJ, Song JM, Kihara T, Daimon M, Shin MS, Thomas JD, Shiota T. Determinants of recurrent or residual functional tricuspid regurgitation after tricuspid annuloplasty. Circulation Supplement 2006;114(1 Suppl):I582-7.

158. **Fukuda S, Saracino G, Matsumura Y, Daimon M, Tran H, Greenberg NL, Hozumi T, Yoshikawa J, Thomas JD, Shiota T. Three-dimensional geometry of tricuspid annulus in healthy subjects and patients with functional tricuspid regurgitation: A real-time three-dimensional echocardiographic study. Circulation Supplement 2006;114(1 Suppl):I492- 8.

159. **Daimon M, Fukuda S, Adams DH, McCarthy PM, Gillinov AM, Carpentier A, Filsoufi F, Abascal VM, Rigolin VH, Salzberg S, Huskin A, Langenfeld M, Shiota T. Mitral valve repair with Carpentier-McCarthy-Adams IMR Etlogix annuloplasty ring for Ischemic mitral regurgitation: Early echocardiographic results from a multi-center study. Circulation Supplement 2006;114(1 Suppl):I588-93.

160. **Song JM, Qin JX, Kongsaerepong V, Shiota M, Agler DA, Smedira NG, McCarthy PM, Gillinov AM, Thomas JD, Shiota T. Determinants of ischemic mitral regurgitation In patients with chronic anterior wall myocardial infarction: A real-time three-Dimensional echocardiography study. Echocardiogr 2006;23(8):650- 7.

161. **Kongsaerepong V, Shiota M, Gillinov AM, Song JM, Fukuda S, McCarthy PM, Williams T, Savage R, Daimon M, Thomas JD, Shiota T. Echocardiographic predictors of successful-v-unsuccessful mitral valve repair in ischemic mitral regurgitation. Am J Cardiol 2006;98(4):504-8.

162. **Song JM, Fukuda S, Kihara T, Shin MS, Garcia MJ, Thomas JD, Shiota T. Value of mitral valve tenting volume determined by real-time three-dimensional echocardiography in patients with functional mitral regurgitation. Am J Cardiol 2006;98(8):1088-93.

163. **Shin MS, Fukuda S, Song JM, Tran H, Oryszak S, Thomas JD, Shiota T. Relationship between left atrial and left ventricular function in hypertrophic cardiomyopathy: A real-time 3-dimensional echocardiographic study. J Am Soc Echocardiogr 2006;19(6):796-801

164. **Song JM, Fukuda S, Lever HM, Daimon M, Agler DA, Smedira NG, Thomas JD,

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Shiota T. Asymmetry of systolic anterior motion of the mitral valve in patients with hypertrophic obstructive cardiomyopathy: A real-time three-dimensional echocardio graphic study. J Am Soc Echocardiogr 2006;19(9):1129-35.

165. **Asada-Kamiguchi J, Jones M, Greenberg NL, Popovic ZB, Tsujino H, Zetts AD, Qin JX, Garcia MJ, Thomas JD, Shiota T. Intraventricular pressure gradients in left ventricular determined by color-m-mode Doppler method: An animal study. J Am Soc Echocardiogr 2006;19(9):1112-8.

166. **Fukuda S, Gillinov AM, Song JM, Daimon M, Kongsaerepong V, Thomas JD, Shiota T. Echocardiographic insights into atrial and ventricular mechanisms of functional tricuspid regurgitation. Am Heart J 2006; 152(6): 1208-14.

167. Kwan J, Gillinov AM, Thomas, JD, Shiota T. Geometric predictor of significant mitral regurgitation in patients with severe ischemic cardiomyopathy, undergoing : A real-time 3D echocardiographic study. Eur J Echocardiogr 2006

168. Kwan J, Kim GC, Jeon MJ, Kim DH, Shiota T, Thomas JD, Park KS, Lee WH. 3D geometry of a normal tricuspid annulus during systole: A comparison study with the mitral annulus using real-time 3D echocardiography. Eur J Echocardiogr 2007;8(5):375-83.

169. **Daimon M, Gillinov AM, Liddicoat JR, Saracino G, Fukuda S, Koyama Y, Hayase M, Cohn WE, Ellis SG, Thomas JD, Shiota T. Dynamic change in mitral annular area and motion during percutaneous mitral annuloplasty for ischemic mitral regurgitation: Preliminary animal study with real-time 3-Dimensional echocardiography. J Am Soc Echocardiogr 2007;20(4):381-8.

170. **Kim YJ, Jones M, Greenberg NL, Popovic ZB, Sitges M, Bauer F, Thomas JD, Shiota T. Evaluation of left ventricular contractile function using noninvasively determined single-beat-end-systolic elastance in mitral regurgitation: Experimental validation and clinical application. J Am Soc Echocardiogr 2007;20:1086-1092.

171. **Fukuda S, Gillinov AM, McCarthy PM, Matsumura Y, Thomas JD, Shiota T. Echocardiographic follow-up of tricuspid annuloplasty with a new three-dimensional ring in patients with functional tricuspid regurgitation. J Am Soc Echocardiogr 2007;(11):1236-1242.

172. **Fukuda S, Shiota T. Tricuspid regurgitation and right ventricular asynchrony. Reply to letters to the editor. Am Heart J. 2007;154(1):e11.

173. **Matsumura Y, Fukuda S, Tran H, Greenberg NL, Agler DA, Wada N, Toyono M, Thomas JD, Shiota T. Geometry of the proximal isovelocity surface area in mitral regurgitation by three-dimensional color Doppler echocardiography: Difference

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between functional mitral regurgitation and prolapse regurgitation. Am Heart J. 2008;155(2):231-238.

174. **Daimon M, Saracino G, Gillinov AM, Koyama Y, Fukuda S, Kwan J, Song JM, Kongsaerepong V, Agler DA, Thomas JD, Shiota T. Local dysfunction and asymmetrical deformation of mitral annular geometry in ischemic mitral regurgitation: a novel computerized 3D echocardiographic analysis. Echocardiography 2008;25(4):414-23.

175. **Fukuda S, Gillinov AM, Liddicoat JR, Saracino G, Hayase M, Cohn WE, Schneider CW, Shiota T. Maintenance of geometric alterations associated with percutaneous mitral valve repair: Real-time three-dimensional echocardiographic assessment in an ovine model. J Heart Valve Disease 2008;17:276-282.

176. Notomi Y, Popovic ZB, Yamada H, Wallick DW, Martin MG, Oryszak SJ, Shiota T, Greenberg NL, Thomas JD. Ventricular untwisting: A temporal link between left ventricular relaxation and suction. Am J Physiol, 2008;294(1):H505-13.

177. **Yalçin F, Shiota M, Greenberg N, Thomas JD, Shiota T. Real-time three- dimensional echocardiography evaluation of mitral annular characteristics in patients with myocardial hypertrophy. Echocardiography 2008;25(4):424-8.

178. **Fukuda S, Lever HL, Stewart WJ, Tran H, Song JM, Shin MS, Greenberg NL, Wada N, Matsumura Y, Toyono M, Smedira NG, Thomas JD, Shiota T. Diagnostic value of left ventricular outflow area in patients with hypertrophic cardiomyopathy: A real-time three-dimensional echocardiographic study. J Am Soc Echocardiogr 2008;21:789-95.

179. ** Toyono M, Pettersson G, Matsumura Y, Wada N, Fukuda S, Yamano T, Takasaki K, Shiota T. Preoperative and postoperative mitral valve prolapse and regurgitation in adult patients with secundum atrial septal defects. Echocardiography 2008;25:1086-93.

180. **Matsumura Y, Saracino G, Sugioka K, Tran H, Greenberg NL, Wada N, Toyono M, Fukuda S, Hozumi T, Thomas JD, Yoshikawa J, Yoshiyama M, Shiota T. Determination of regurgitant orifice area with the use of a new three-dimensional flow convergence geometric assumption in functional mitral regurgitation. J Am Soc Echocardiogr 2008;21(11):1251-6

181. **Matsumura Y, Gillinov AM, Toyono M, Wada N, Yamano T, Thomas JD, Shiota T. Usefulness of left ventricular shape to predict the early recovery of left ventricular function after isolated for aortic valve stenosis. Am J Cardiol 2008;102(11):1530-4. Epub 2008.

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182. **Shiota T. 3D echocardiography: The present and the future. J Cardiol 2008;52(3):169-85.

183. **Takasaki K, Gillinov AM, Yamano T, Matsumura Y, Toyono M, Shiota T. Detection of left ventricular dysfunction with Tei Index in normal ejection fraction patients with mitral regurgitation before metal valve surgery. Am J Cardiol 2009;103:1011-1014.

184. **Yamano T, Gillinov AM, Wada N, Matsumura Y, Toyono M, Thomas JD, Shiota T. Doppler-derived preoperative mitral regurgitation volume predicts postoperative left ventricular dysfunction after mitral valve repair. Am Heart J 2009;157(5):875-82.

185. **Kihara T, Gillinov AM, Takasaki K, Fukuda S, Song JM, Shiota M, ShiotaT. Mitral regurgitation associated with mitral annular dilation in patients with lone atrial fibrillation: an echocardiographic study. Echocardiography 2009;26(8):885-9.

186. **Toyono M, Fukuda S, Gillinov AM, Pettersson GB, Matsumura Y, Wada N, Yamano T, Takasaki K, Shiota T. Different determinants of residual tricuspid regurgitation after tricuspid annuloplasty: comparison of atrial septal defect and mitral valve prolapse. J Am Soc Echocardiogr 2009;22(8):899-903.

187. Sack S, Kahlert P, Bilodeau L, Pierard LA, Lancellotti P, Legrand V, Bartunek J, Vanderheyden M, Hoffmann R, Schauerte P, Shiota T, Marks DS, Erbel R, Ellis SG. Percutaneous transvenous mitral annuloplasty: Initial human experience with a novel coronary sinus implant device. Circulation Cardiovasc Interv 2009;2(4):277-84.

188. **Toyono M, Krasuski RA, Pettersson GB, Matsumura Y, Yamano T, Shiota T. Persistent tricuspid regurgitation and its predictor in adult patients after percutaneous and iisolated surgical closure of secundum atrial septal defect. Am J Cardiol 2009;104:856-861.

189. **Shiota T. 3D Echocardiography: Evaluation of the right ventricle. Curent Opinion in Cardiology 2009;24(5):410-4.

190. **Saraiva R, Yamano T, Matsumura Y, Takasaki K, Toyono M, Agler DA, Greenberg N, Thomas JD, Shiota T. Left atrial function assessed by real-time 3D echocardiography is related to right ventricular systolic pressure in chronic mitral regurgitation. Am Heart J 2009;158:309-16.

191. **Takasaki K, Gillinov AM, Kihara T, Shiota M, Shiota T. Letter (Reply). Echocardiography2010;27(2):219.

192. **Biner S, Kar S, Siegel RJ, Rafique A, Shiota T. Value of color doppler three- dimensional transesophageal echocardiography in the percutaneous closure of mitral prosthesis paravalvular leak.Am J Cardiol 2010;105:984-989.

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193. **Daimon M, Saracino G, Fukuda S, Koyama Y, Kwan J, Song JM, Agler DA, Gillinov AM, Thomas JD, Shiota T. The effect of dynamic change of mitral annular geometry and motion in ischemic mitral regurgitation: a novel computerized 3D Echo method. Echocardiography 2010;27(9):1069-77.

194. **Saraiva RM, Matsumura Y, Yamano T, Greenberg N, Thomas JD, Shiota T. Relation of left atrial dysfunction to hypertension in patients with and left ventricular systolic dysfunction Am J Cardiol 2010;106:409- 416.

195. Biner S, Rafique A, Rafii F, Tolstrup K, Noorani O, Shiota T, Gurudevan S, Siegel RJ. Reproducibility of proximal isovelocity surface area, vena contracta, and regurgitant jet area for assessment of mitral regurgitation severity. J Am Coll Cardiol 2010;3:235-243.

196. **Matsumura Y, Gillinov AM, Toyono M, Oe H, Yamano T, Takasaki K, Saraiva RM, Shiota T. Echocardiographic predictors for persistent functional mitral regurgitation after aortic valve replacement in patients with aortic valve stenosis. Am J Cardiol 2010;106(5):701-6.

197. Nalawadi S, Siegel RJ, Wolin E, Yu R, Trento A, Shiota T, Tolstrup K, Luthriger D, Gurudevan S. Morphologic features of carcinoid heart disease as assessed by three- Dimensonal transesophageal Echocardiography. Echocardiography 2010;27(9):1098- 105

198. **Shimada YJ, Shiota M, Siegel RJ, Shiota T. Accuracy of right ventricular volumes and function determined by 3-dimensional echocardiography in comparison with magnetic resonance imaging: A meta-analysis study. J Am Soc Echocardiogr 2010;23(9):943-53.

199. **Shiota M, Gillinov AM, Takasaki K, Fukuda S, Shiota T. Recurrent mitral reguritation late after annuloplasty for ischemic mitral regurgitation. Echocardiography 2011; 28(2):161-6.

200. Thompson KA, Shiota T, Tolstrup K, Gurudevan SV, Siegel RJ. The utility of three- dimensional transesophageal echocardiography in the diagnosis of valvular perforations. Am J Cardiol 2011:107(1)100-2.

201. **Shimada YJ, Shiota T. A meta-analysis and investigation for the source of bias ventricular volumes and function by three-dimensional echocardiography in comparison with magnetic resonance imaging. Am J Cardiol 2011;107(1):126-38.

202. Thompson KA, Shiota T, Tolstrup K, Gurudevan SV, Siegel RJ. Utility of three-

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dimensional transesophageal echocardiographyin the diagnosis of valvular perforations. Am J Cardiol 2011;107(1):100-2.

203. Biner S, Perk G, Kar S, Rafique A, Slater J, Shiota T, Hussaini A, Chou S, Kronzon I, Siegel RJ. Utility of combined two-dimensional and three-dimensional transesophageal imaging for catheter-based mitral valve clip repair of mitrial reguritation. J Am Soc Echocardiogr 2011;24(6):611-7.

204. Tornic J, Jarrett C, Shiota T, Gillinov AM, Mihaljevic T. Severe mitral regurgitation in an adult patient with cor triatriatum. The Journal of Heart Valve Disease 2011; 20(2):234-6.

205. Tolstrup K, Shiota T, Gurudevan SV, Luthringer D, Luo H, Siegel RJ. Left atrial myxomas: correlation of two-dimensinal and live three-dimensional transesophageal echocardiography with the clinical and pathologic findings. J Am Soc Echocardiogr 2011;24(6):618-24.

206. **Izumo M, Nalawadi S, Shiota M, Das J, Dohad S, Kuwahara E, Fukuoka Y, Siegel RJ, Shiota T. Mechanisms of acute mitral regurgitation in patients with takotsubo cardiomyopathy: an echocardiographic study. Circulation: Cardiovascular Imaging 2011; 4(4):392-8.

207. Fukuda S, Watanabe H, Shimada K, Aikawa M, Kono Y, Jissho S, Taguchi H, Umemura J, Yoshiyama M, Shiota T, Sumiyoshi T, Yoshikawa J. Left atrial thrombus and prognosis after anticoagulation therapy in patients with atrial fibrillation. J Cardiol. 2011;58(3):266-77.

208. Kulkarni M, Conte AH, Huang A, Lubin L, Shiota T, Kar S. Coronary artery disease, acute myocardial infarction, and a newly developing ventricular septal defect: surgical repair or percutaneous closure? J Cardiothorac Vasc Anesth. 2011 ;25(6):1213-6.

209. Shimada YJ, Ishikawa K, Kawase Y, Ladage D, Tilemann L, Shiota T, Hajjar RJ. Comparison of Left Ventricular Stroke Volume Assessment by Two- and Three-Dimensional Echocardiography in a Swine Model of Acute Myocardial Infarction Validated by Thermodilution Method. Echocardiography. 2012; 29(9):1091-5.

210. Jilaihawi H, Kashif M, Fontana G, Furugen A, Shiota T, Friede G, Makhija R, Doctor N, Leon MB, Makkar RR. Cross-sectional computed tomographic assessment improves accuracy of aortic annular sizing for transcatheter aortic valve replacement and reduces the incidence of paravalvular aortic regurgitation. J Am Coll Cardiol. 2012;59(14):1275-86.

211. Nalawadi SS, Tolstrup K, Cuk O, Shiota T, Gurudevan SV, Siegel RJ; Heart

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Institute, Cedars-Sinai Medical Center, Los Angeles, California. Atropine as an adjunct to supine bicycle stress echocardiography: an alternative strategy to achieve target heart rate or rate pressure product. Eur Heart J Cardiovasc Imaging. 2012;13(7):612-6.

212. **Shimada YJ, Shiota T. Underestimation of left atrial volume by three-dimensional echocardiography validated by magnetic resonance imaging: a meta-analysis and investigation of the source of bias. Echocardiography. 2012 ;29(4):385-90.

213. **Miyata-Fukuoka Y, Izumo M, Shimada YJ, Kuwahara E, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Left atrial size and function are related to in coronary artery disease. Echocardiography. 2012;29(5):535-40.

214. **Saitoh T, Shiota M, Izumo M, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Comparison of left ventricular outflow geometry and aortic valve area in patients with aortic stenosis by 2-dimensional versus 3-dimensional echocardiography. Am J Cardiol. 2012;109(11):1626-31.

215. **Saitoh T, Izumo M, Furugen A, Tanaka J, Miyata-Fukuoka Y, Gurudevan SV, Tolstrup K, Siegel RJ, Kar S, Shiota T. Echocardiographic evaluation of iatrogenic atrial septal defect after catheter-based mitral valve clip insertion. Am J Cardiol. 2012;109(12):1787-91.

216 **Shimada YJ, Shiota T. Meta-analysis of accuracy of left ventricular mass measurement by three-dimensional echocardiography. Am J Cardiol. 2012;110(3):445-52.

217. Perk G, Biner S, Kronzon I, Saric M, Chinitz L, Thompson K, Shiota T, Hussani A, Lang R, Siegel R, Kar S. Catheter-based left atrial appendage occlusion procedure: role of echocardiography. Eur Heart J Cardiovasc Imaging. 2012 ;13(2):132-8.

218. **Izumo M, Shiota M, Saitoh T, Kuwahara E, Fukuoka Y, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Non-Circular Shape of Right Ventricular Outflow Tract: A Real-Time Three-Dimensional Transesophageal Echocardiography Study. Circ Cardiovasc Imaging. 2012;5(5):621-7.

219. **Shibayama K, Watanabe H, Sasaki S, Mahara K, Tabata M, Fukui T, Takanashi S, Sumiyoshi T, Tomoike H, Shiota T. Impact of Regurgitant Orifice Height for Mechanism of Aortic Regurgitation: Three-Dimensional Transesophageal Echocardiography Analysis. J Am Coll Cardiol Cardiovasc Imaging. 2013;6(12): 1347-9.

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220. Makkar RR, Jilaihawi H, Chakravarty T, Fontana GP, Kapadia S, Babaliaros V, Cheng W, Thourani VH, Bavaria J, Svensson L, Kodali S, Shiota T, Siegel R, Tuzcu EM, Xu K, Hahn RT, Herrmann HC, Reisman M, Whisenant B, Lim S, Beohar N, Mack M, Teirstein P, Rihal C, Douglas PS, Blackstone E, Pichard A, Webb JG, Leon MB. Determinants and Outcomes of Acute Transcatheter Valve-in-Valve Therapy or Embolization: A Study of Multiple Valve Implants in the US PARTNER Trial. J Am Coll Cardiol. 2013;S0735-1097(13)01879-2.

221. Jilaihawi H, Doctor N, Kashif M, Chakravarty T, Rafique A, Makar M, Furugen A, Nakamura M, Mirocha J, Gheorghiu M, Stegic J, Okuyama K, Sullivan DJ, Siegel R, Min JK, Gurudevan SV, Fontana GP, Cheng W, Friede G, Shiota T, Makkar RR. Aortic annular sizing for transcatheter aortic valve replacement using crosssectional 3-dimensional transesophageal echocardiography. J Am Coll Cardiol. 2013;61(9):908-16.

222. Kitada R, Fukuda S, Watanabe H, Oe H, Abe Y, Yoshiyama M, Song JM, Sitges M, Shiota T, Ito H, Yoshikawa J. Diagnostic accuracy and cost-effectiveness of pocket- sized transthoracic echocardiographic imaging device. Journal Clin Cardiol. 2013 in press.

223. **Tanaka J, Izumo M, Fukuoka Y, Saitoh T, Harada K, Harada K, Gurudevan S, Tolstrup K, Siegel RJ, Shiota T. Comparison of Two-Dimensional Versus Real- Time Three-Dimensional Transesophageal Echocardiography for Evaluation of Patent Foramen Ovale. Am J. Cardiol 2013; 111:1052-1056.

224. **Harada K, Saitoh T, Tanaka J, Shibayama K, Berdejo J, Shiota T. Valvuloarterial Impedance (Zva), but Not Aortic Stenosis Severity, Predicts Syncope in Aortic Stenosis. Circulation: Cardiovascular Imaging 2013;6(6):1024-31.

225. Nakamura M, Mirocha J, Gheorghiu M, Stegic J, Okuyama K, Sullivan DF, Siegel RJ, Min JK, Gurudevan SV, Fontana GP, Cheng W, Friede G, Shiota T, Makkar RR. Aortic annular sizing for transcatheter aortic valve replacement using crosssectional 3-dimensional transesophageal echocardiography. J Am Coll Cariol. 2013;61(9):908- 16.

226. Makkar RR, Jilaihawi H, Chakravarty T, Fontana GP, Kapadia S, Babaliaros V, Cheng W, Thourani VH, Bavaria J, Svensson L, Kodali S, Shiota T, Siegel R, Tuzcu EM, Xu K, Hahn RT, Herrmann HC, Reisman M, Whisenant B, Lim S, Beohar N, Mack M, Teirstein P, Rihal C, Douglas PS, Blackstone E, Pichard A, Webb JG, Leon MB. Determinants and outcomes of acute transcatheter valve-in- valve therapy or embolization: a study of multiple valve implants in the U.S. PARTNER trial (Placement of AoRTic TraNscathetER Valve Trial Edwards SAPIEN Transcatheter Heart Valve). J Am Coll Cardiol. 2013; 30;62(5):418-30.

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227. Kitada R, Fukuda S, Watanabe H, Oe H, Abe Y, Yoshiyama M, Song JM, Sitges M, Shiota T, Ito H, Yoshikawa J. Diagnostic accuracy and cost-effectiveness of a pocket-sized transthoracic echocardiographic imaging device. Clin Cardiol. 2013;Oct;36(10): 603-10.

228. **Mihara H, Shibayama K, Harada K, Berdejo J, Itabashi Y, Makkar RR, Shiota T: Device landing zone calcification predicts significant paravaluvular regurgitation after transcatheter aortic valve replacement: a real-time three-dimensional transesophageal echocardiograpy study. Echocardiography. 2014;31:E142–E144

229. **Saitoh T, Tanaka J, Furugen A, Harada K, Izumo M, Fukuoka Y, Shiota T: Impact of energy loss index and valvuloarterial impedance in patients with aortic stenosis using three-dimensional echocardiography. Echocardiography. 2014 Jul 22. [Epub ahead of print]

230. **Shibayama, K, Harada K, Berdejo J, Mihara H, Tanaka J, Gurudevan SV, Siegel R, Jilaihawi H, Makkar RR, Shiota T: Effect of transcatheter aortic valve replacement on the mitral valve apparatus and mitral regurgitation: A real time three dimensional transesophageal echocardiography study. Circ Cardiolvasc Imaging 2014;7:344-51,

231. ** Berdejo J, Shibayama K, Harada K, Tanaka J, Mihara H, Gurudevan SV, Siegel RJ, Shiota T. Evaluation of Vegetation Size and its Relationship with Embolism in Infective : A Real-time Three-dimensional Transesophageal Echocardiography Study. Circ Cardiovasc Imaging. 2014 Jan;7(1):149-54.

232. **Mihara H, Shibayama K, Harada K, Berdejo J, Itabashi Y, Shiota T. LV outflow tract area in discrete subaortic stenosis and hypertrophic obstructive cardiomyopathy: a real-time 3-dimensional transesophageal echocardiography study. JACC Cardiovasc Imaging. 2014 Apr;7(4):425-8.

234. **Shiota T. Role of Modern 3D Echocardiography in Valvular Heart Disease. Korean J Intern Med. 2014. Nov;29(6):685-702. Epub 2014 Oct 31.

235. **Shibayama K, Harada K, Berdejo J, Tanaka J, Mihara H, Itabashi Y, Shiota T. Comparison of Aortic Root Geometry with Bicuspid versus Tricuspid Aortic Valve: Real-Time Three-Dimensional Transesophageal Echocardiographic Study. J Am Soc Echocardiogr 2014 Nov;27(11):1143-52. Doi: 10.1016/j.rvho.2014.07.008. Epub 2014 Aug 22.

236. Jilaihawi H, Makkar RR, Kashif M, Okuyama K, Chakravarty T, Shiota T, Friede G, Nakamura M, Doctor N, Rafique A, Shibayama K, Mihara H, Trento A, Cheng W, Friedman J, Berman D, Fontana GP. A revised methodology for aortic-valvar complex calcium quantification for transcatheter aortic valve implantation. Eur Heart J Cardiovasc Imaging 2014 Dec; 15(12):1324-32. Doi: 10.1093/ehjci/jeu162. Epub 2014 Sep 3

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237. **Izumo M, Shiota M, Nalawadi S, Das J, Dohad S, Kuwahara E, Fukuoka Y, Siegel RJ, Shiota T. Determinants of Secondary Pulmonary Hypertension in Patients with Takotsubo Cardiomyopathy. 2015 Apr 16. Doi: 10.1111/echo.12949. [Epub ahead of print]

238. **Itabashi Y, Shibayama K, Mihara H, Utsunomiya H, Berdejo J, Arsanjani R, Siegel R, Chakravarty T, Jilaihawi H, Makkar RR, Shiota T. Significant Reduction in Mitral Regurgitation Volume is the Main Contributor for Increase in Systolic Forward Flow in Patients with Functional Mitral Regurgitation after Transcatheter Aortic Valve Replacement: Hemodynamic Analysis Using Echocardiography. Echocardiography. 2015 Mar 26. Doi: 10.1111/echo.1293. [Epub ahead of print] PMID: 25817306

239. Zhang L, Narayanan K. Chugh H, Shiota T, Zheng ZJ, Chugh SS. Factors Influencing Utilization of the Primary Prevention Implantable Defibrillator. PLoS One. 2015 Mar 20;10(3):e0121515. Doi: 10.1371/journal.pone.0121515. eCollection 2015. PMID: 25794248

240. **Mihara H, Shibayama K, Berdejo J, Harada K, Itabashi Y, Siegel RJ, Kashif M, Jilaihawi H, Makkar RR, Shiota T. Impact of Device Landing Zone Calcification on Paravalvular Regurgitation after Transcatheter Aortic Valve Replacement: A Real- time Three-dimensional Transesophageal Echocardiographic Study. J Am Soc Echocardiogr. 2015 Apr;28(4):404-14. Doi: 10.1016/j.echo.2014.11.013. Epub 2015 Jan 2. PMID: 25560483

** denotes Shiota M.D. as corresponding author

BOOK CHAPTERS

1. *Hada Y, Shiota T, Sakamoto T: Valvular Heart Disease. Medicina 1987;24:1029- 1036.

2. *Shiota T: Mitral Stenosis. Medical Practice 1989;6:1389-1393.

3. *Shiota T: Cardiac Tumor and Thrombosis. Medical Practice 1990;7:2093-2098.

4. *Shiota T: Cardiac Arrhythmias. Nankodo. Edited by Sugimoto T. Tokyo. 1992;489-92.

5. *Shiota T: Clinical Echocardiography. Bunkodo. Edited by Yazaki Y. Tokyo. 1993;77-83; 268-75.

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6. *Shiota T: Congenital Heart Disease. Nakayama Shoten, Tokyo. 1997 (on CD- ROM)

7. Shiota T: Transesophageal Echocardigraphy (Congenital Heart Disease), Edited by Omoto R, Shindan to Chiryo-sha, Tokyo. 2000.

8. Savage RM, Shiota T, Stewart W, Wallace LK, Gillinov AM. Assessment in mitral valve surgery. Comprehensive textbook of intraoperative transesophageal echocardiography. Lippicott Williams & Wilkins, 2005.

9. Chuang HH, Torok TS, Jordaens LJ, Shiota T. Three-dimensional echocardiography – future applications in interventional cardiology. Intracardiac Echocardiography in Interventional , 2006.

10. Shiota T: Surgical Treatment of Hypertrophic Cardiomyopathy, New Practice in Clinical Cardiology 10. Edited by Isobe M and Matsuzaki M. Bunkodo, Tokyo. 2007;156-159.

11. Shiota T: Editor-in-Chief and chapter author, 3D Echocardiography, London, England, Informa Healthcare, Taylor & Francis, 2007.

12. Shiota T: Mitral Insufficiency. Noninvasive Cardiovascular Imaging a Multimodality Approach. Edited by Garcia MJ, Lippicott Williams & Wilkins, 2010; 426-440.

15. *Shiota T. Percutaneous Intervention and Echocardiography, II. Valvular Heart Disease, New Practice in Clinical Cardiology 17. Edited by Yoshikawa J & Nakatani S. Bunkodo, Tokyo. 2011;210-214

16. Shiota T: Transesophageal Echocariography, 2nd ed., Clinical Significance of Real- Time 3D Transesophageal Echocardiography, Edited by Omoto R, Konstadt SN & Orihashi K. Shindan to Chiryo-sha, Tokyo. 2012.

18. *Shiota T. Preoperative and Intraoperative Evaluation of MitraClip by Echocardiography. Manual of Echocardiography; Interventional Treatments for Structural Heart Disease. Medical View. Tokyo. 2013 in press.

19. *Shiota T. Intraoperative guide of MitraClip by Transesophageal Echocardiography; Diagnosis of Complications. Echocardiography Manual; Interventional Treatments for Structural Heart Disease. Medical View, Tokyo. 2013 in press.

TEXTBOOKS

13. Shiota T: Textbook, Clinical 3D Echocardiography: A Comparison with 2D

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Echocardiography, Case Presentations. Vector Core, Tokyo. 2010

14. *Shiota T: Clinical 3D Echocardiography: A Comparison with 2D Echocardiography; Learning from Case Presentations, Vector Core, Tokyo. 2011 17. Shiota T: Editor-in-Chief and chapter author, 3D Echocardiography, CRC Press/Informa Healthcare, Taylor & Francis, London, England. 2013.

ARTICLES

1. Shiota T. How to use PISA or flow convergence for assessing valvular regurgitation. Cardiac Ultrasound Today. Chrestomathic Press, Inc. 1999;5(5):77-92.

2. *Shiota T. Indication and Prognosis of Batista Operation. Cardiac Practice 1999;10;415-41.

3. Shiota T. Practical Use of PISA or flow convergence for assessing valvular regurgitation in Clinic. Pediatric Ultrasound Today. Chrestomathic Press, Inc. 2000;5(2),17-32.

4. *Shiota T. Surgical treatment for heart failure patients: Dor and Batista operation. Annulus Review 2000: Cardiology. 2000;242-247.

5. *Shiota T. Dor and Batista operation. Heart View. Tokyo, 2000; 4, 447-451.Shiot

6. Shiota T. Clinical assessment of atrioventricular valvular regurgitation: mitral and tricuspid regurgitation. Cardiac Ultrasound Today. Chrestomathic Press, Inc. 2000;6(2), 97-112.

7. Shiota T. Illustrative case presentations of aortic regurgitation. Cardiac Ultrasound Today. Chrestomathic Press, Inc. 2001;7(1):1-16.

8. Shiota T. Echocardiographic presentations in surgically managed end-stage heart failure. Cardiac Ultrasound Today. Chrestomathic Press, Inc. 2003;9(4):67-84

9. Shiota T. Echocardiographic case presentations of tricuspid regurgitation. Cardiac Ultrasound Today. Chrestomathic Press, Inc. 2005;11(3)45-64.

10. Shiota T. Echocardiographic features of ischemic mitral regurgitation. Cardiac Ultrasound Today. Chrestomathic Press, Inc. 2006;12(2):25-44.

11. Shiota T. Echocardiography of hypertrophic cardiomyopathy. Cardiac Ultrasound Today. Chrestomathic Press, Inc. 2007;13(4):77-100.

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12. Shiota T. Live TEE 3D: A revolution in Echocardiography. Cardiac Ultrasound Today. Chrestomathic Press, Inc. 2008;13(4):77-100.

13. Shiota T. Diagnostic Challenges in Daily Practice in the Echocardiography Laboratory. Cardiac Ultrasound Today. ChrestomathicPress, Inc.2010;16(2/3):23- 75.

14. *Shiota T. Medical Practice in the U.S. Journal for Cardiologists. Nankodo. 2011;19(1):156-62.

15. *Shiota T. MitraClip and Echocardiograpy; Role of Echocardiography in Cardiovascular Surgery, Journal of Clinical Echocardiography, Bunkodo, Tokyo 2011;12(10):978-983

16. *Shiota T. Evaluation of Aortic Regurgitation: Case Presentations. Cardiac Ultrasound Today. Chrestomathic Press, Inc. 2013;19(3):45-64.

17. *Tanaka J. Shiota T. MitraClip and Echocardiography, Medical Practice, Bunkodo, Tokyo. 2013;30(6):1035-37.

18. *Shiota T. Catheter-based Mitral Valve Repair. Clinical Engineering. Gakken Medical Shunjunsha, Tokyo. 2013;24(8):823-831.

19. *Shibayama, K, Shiota T. 3D Echocardiography. Journal of Clinical Echocardiography, Bunkodo, Tokyo 2013; 14(11);1072-79.

20. *Mihara H, Shiota T. Repair of Mitral Regurgitation. Journal of Clinical Echocardiography, Bunkodo, Tokyo 2014; 15(7)664-73.

21. *Shiota T. Heart Team. Respiration and Circulation, Igaku Shoin, Tokyo 2014;62(6):568-77. nt of Atrioventricular Valvular Regurgitation: Mitral and Tricuspid Regurgitation. Cardiac Ultrasound Tod

BOOK REVIEWS

1. Shiota T, Sahn DJ. Transesophageal Echocardiography. Basic principles and clinical applications. AJ Labovitz and AC Pearson. Philadelphia: Lea & Febiger, 1993:157.

ABSTRACTS

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1. Amano K, Takenaka K, Hasegawa I, Suzuki J, Shiota T, Takahashi H, Sakamoto T, Sugimoto K: Determinations of left ventricular function in thyrotoxic cardiac failure. Echocardiogr 1987;4 (suppl):445.

2. Takenaka K, Sakamoto T, Amano K, Oku J, Fujinami K, Murakami T, Hada Y, Hasegawa I, Suzuki J, Shiota T, Takahashi H, Sugimoto K: Assessment of left ventricular filling in diabetics by pulsed Doppler echocardiography. Echocardiogr 1987; 4 (suppl):460.

3. Hasegawa I, Sakamoto T, Hada Y, Amano K, Takenaka K, Takahashi H, Suzuki J, Shiota T: Mid-systolic mitral regurgitation in dogs with drug-induced left ventricular outflow obstruction. Circulation 1987;76 (suppl IV):518.

4. Hasegawa I, Sakamoto T, Hada Y, Amano K, Takenaka K, Takahashi J, Suzuki J, Shiota T: Relationship between mid-systolic mitral regurgitation and left ventricular outflow obstruction in hypertrophic cardiomyopathy. Circulation 1987;76 (suppl IV):249.

5. Amano W, Takenaka K, Sakamoto T, Hasegawa I, Suzuki J, Shiota T, Amano K, Takahashi H, Sugimoto T. "Moyamoya" echoes in the left atrial cavity in mitral stenosis: Transesophageal echocardiographic study. J Cardiogr 1988;19 (suppl):314.

6. Hasegawa I, Amano W, Takenaka K, Sakamoto T, Suzuki J, Shiota T: Separation of systolic right atrial filling in experimental cardiac tamponade. Circulation 1989;80 (suppl II):668.

7. Igarashi T, Takenaka K, Sakamoto T, Amano W, Shiota T: Normal values for transesophageal echocardiographic examination. Circulation 1990; (suppl III):30.

8. Takenaka K, Shiota T, Sakamoto T, Amano W, Suzuki J, Igarashi T: Diagnosis of patent ductus arteriosus by transesophageal Doppler echocardiography. Circulation 1990;82 (suppl III):31.

9. Hasegawa I, Amano W, Takenaka K, Sakamoto T, Shiota T, Suzuki J: Two- dimensional echocardiographic evidence for concurrence of right ventricular suction and collapse in cardiac tamponade. Circulation 1990;82 (suppl III):418.

10. Shiota T, Takenaka K, Sakamoto T, Saito Y, Hasegawa I, Suzuki J, Amano W, Amano K, Takahashi H: Venous hum and innominate vein flow in patients with chronic anemia. Circulation 1990;82 (suppl III):578.

11. Weintraub RG, Golebiovski P, Shiota T, Sahn DJ. Intraoperative transoesophageal echocardiography (TOE) during surgical repair of congenital heart disease. Cardiac Society of Australia, Aug 1992.

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12. Shiota T, Valdes-Cruz LM, Sahn DJ, Jones M, Shandas R, Murillo A, Yamada I, Weintraub R. Estimation of cardiac output and mitral orifice area using a proximal flow convergence method: Validation studies in animal model with chronic mitral stenosis. J Am Coll Cardiol 1992;19:390A.

13. Shiota T, Moises V, Sahn DJ, Shandas R, Zhang J, Weintraub R. Influence of orifice shape on color Doppler flow convergence: An in-vitro study. J Am Coll Cardiol 1992;19:358A.

14. Gharib M, Shiota T, Kang SU, McCann H, Sahn DJ. Dynamic filling characteristics of the left ventricle fulfill hydrodynamic constraints for efficient energy transfer. J Am Coll Cardiol 1992;19:332A.

15. Zhang J, Shiota T, Shandas R, Weintraub R, Sahn DJ, Liepmann D. The effect of different shaped adjacent surfaces on regurgitant jet area: Comparison between color Doppler images and laser-induced fluorescent dye visualization. J Am Coll Cardiol 1992; 19:332A.

16. Omoto R, Sahn DJ, Kyo S, Weintraub R, Shiota T. A new 8mm matrix probe suitable for providing simultaneous biplane transesophageal visualization in pediatric and adult patients. J Am Coll Cardiol 1992;19:235A..

17. Weintraub R, Shiota T, Zhang J, Omoto R, Kyo S, Rothman A, Hellenbrand W, Ritter R, Valdes-Cruz LM, Sahn DJ. Biplane transesophageal echocardiography (TEE) during interventional cardiac catheterization in infants and children. J Am Coll Cardiol 1992;19:148A.

18. Ricou F, Rothman A, Weintraub R, Crowley R, Archangeli R, Shiota T, Zhang J, Sahn DJ. Intraluminal ultrasound imaging through a balloon dilation catheter n an animal model of coarctation of the aorta. J Am Coll Cardiol 1992;19:52A.

19. Shiota T, Teien D, Deng Y, Ewing S, Shandas R, Sahn DJ. Flow acceleration towards and into a long segmental stenosis: Spatial movement of the vena contracta: An in-vitro study using digital color Doppler. Circulation 1992;86:I-1262.

20. Luk G, Rothman A, Shiota T, Weintraub R, Ricou F, Beltran D, Sahn DJ. Intravascular ultrasonic angiographic correclations for dilation of native and recurrent aortic coarctation. Circulation 1992;86:I-1985.

21. Chu Tee S, Shiota T, Weintraub R, Zhang J, Deng YB, Sahn DJ. Intraoperative transesophageal echocardiography during closure of ventricular septal defects. Circulation 1992;86:I-2272.

22. Weintraub R, Shiota T, Zhang J, Omoto R, Kyo S, Rothman A, Hellenbrand W, Ritter S, Valdes-Cruz LM, Sahn DJ. Biplane transesophageal echocardiography

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(TEE) during interventional cardiac catheterization in infants and children. J Am Coll Cardiol 1992;19:148A.

23. Omoto R, Sahn DJ, Kyo S, Weintraub R, Shiota T: A new 8MM Matrix probe suitable for providing simultaneous biplane transesophageal visualization in pediatric and adult patients. J Am Coll Cardiol 1992;19:235A.

24. Gharib M, Shiota T, Kang SU, McCann H, Sahn DJ. Dynamic filling characteristics of the left ventricle fulfill hydrodynamic constraints for efficient energy transfer. J Am Coll Cardiol 1992; 19:332A.

25. Zhang J, Shiota T, Shandas R, Weintraub R, Sahn DJ. The effect of different shaped adjacent surfaces on regurgitant jet area: Comparison between color Doppler images and laser-induced fluorescent dye visualization. J Am Coll Cardiol 1992;19:332A.

26. Shiota T, Moises V, Sahn DJ, Shandas R, Zhang J, Weintraub R. Influence of orifice shape on color Doppler flow convergence: An in vitro study. J Am Coll Cardiol 1992;19:358A.

27. Shiota T, Valdes-Cruz LM, Sahn DJ, Jones M, Shandas, M, Murillo A, Yamada I, Weintraub R, Kang SU, Zhang J. Estimation of cardiac output and mitral orifice area using a proximal flow convergence method: Validation studies in animal model with chronic mitral stenosis. J Am Coll Cardiol 1993; 19:380A.

28. Shiota T, Yamada I, Teien D, Jones M, Shandas R, Sahn DJ. Quantitation of mitral regurgitation using a color Doppler "centerline" flow convergence method: Validation in an animal model with prolapse type mitral regurgitation. J Am Coll Cardiol 1993;2175A.

29. Paik J, Depp M, Shiota T, Mizushige K, Shandas R, Sahn DJ, DeMaria AN. Effect of mitral regurgitant jets on pulmonary venous flow velocity patterns: In vitro experiments. J Am Coll Cardiol 1993;21:144A.

30. Teien D, Shiota T, Jones M, Yamada I, Sahn DJ. Changes in systolic pulmonary venous blood flow in chronic mitral regurgitation: Validation of quantitative applications in an animal model. J Am Coll Cardiol 1993;21:144A.

31. Teien D, Shiota T, Yamada I, Jones M, Sahn DJ. Estimation of the severity of mitral regurgitation volume from invasive pressure measurements obtained during cardiac catheterization: Potential for a nonangiographic grading method studied in an animal model with quantifiable chronic MR. J Am Coll Cardiol 1993;21:241A.

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32. Shiota T, Teien D, Deng YB, Shandas R, Sahn DJ. Estimation of regurgitant flow rate using centerline velocity profiles from digital color Doppler: Application to orifices of different sizes and shapes. J Am Coll Cardiol 1993;21:298A.

33. Shiota T, Teien D, Yamada I, Jones M, Sahn DJ. Variables affecting estimation of regurgitant volume by Doppler color flow mapping of regurgitant jet areas in mitral regurgitation: Investigations in an animal model with quantifiable mitral regurgitation. J Am Coll Cardiol 1993;21:486A.

34. Shiota T, Gong A, Passafini A, Sahn DJ. Methods for estimating dynamic orifice size in flail leaflet-type mitral regurgitation: An animal study. Circulation 1993;88:I-109.

35. Yamada I, Shiota T, Jones M, Teien D, Shandas R, Sahn DJ. A digital color Doppler method for evaluation of mitral regurgitation: Validation in sheep with quantifiable prolapse type mitral regurgitation. Circulation 1993;88: I-110.

36. Luk G, Rothman A, Shiota T, Sohn S, Tong A, Atkinson R, Swensson R, Sahn DJ. Acute and early follow-up intravascular ultrasound findings after balloon dilation of aortic coarctation. Circulation 1993;88: I-388.

37. Deng YB, Shiota T, Shandas R, Zheng J: Determination of the most appropriate Nyquist velocity for applying hemispherical flow convergence equation to calculate flow rate using the transorifice pressure gradient. Circulation 1993;88: I-450.

38. Ge S, Jones M, Shiota T, Yamada I, Valdes-Cruz LM, Sahn DJ. Quantification of flow and effective 3 orifice size for mitral bileaflet mechanical valves: Validation of a new color Doppler "segment of a spheroid" flow convergence method in an animal model. Circulation 1993;88: I-642.

39. Shiota T, Kenny A, Hellenbrand W, Droukas P, Rice MR, Reller MD, Rothman A, Sahn DJ. Intravascular echo assists determination of the anatomy and position of obstructions in right ventricular to pulmonary artery conduits. J Am Coll Cardiol 1994;22A.

40. Beltran D, Rothman A, Shiota T, Sahn DJ, Weintraub R, Rice MJ, Cobanoglu A, Casson H. Transesophageal echo for predicting results for repair of tetralogy of Fallot: Using new high resolution biplan 5-7.5 MHz probes with CW Doppler capability. J Am Coll Cardiol 1994;22A.

41. Arai A, Kenny A, Shiota T, Unger E, Yellowhair D, Passafini A, Matsunaga T, Grauer SE, Pantely G, Sahn DJ. Transpulmonary passage of Aerosomes  a pressure stable, lipid-based echocardiographic contrast agent: Studies in pigs. J Am Coll Cardiol 1994; 25A.

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42. Ludomirsky A, Silberbach M, Kenny A, Shiota T, Rice MJ, Klas B, Brauzowics B, Klein P, Derman R, Sahn DJ. Superiority of rotational scan reconstruction strategies for transthoracic 3-dimensional real-time echocardiographic studies in pediatric patients with CHD. J Am Coll Cardiol 1994;169A.

43. Silberbach M, Davis LE, Shiota T, Woods LL, Chinkers M, Matsuda Y. The new atrial natriuretic peptide antagonist HS-142-1 reverses the natriuresis and diuresis of chonic fetal anemia. J Am Coll Cardiol 1994;236A.

44. Ge S, Shiota T, Deng YB, Shandas R, Sahn DJ. Quantification of flow rate through restrictive orifices using the proximal flow convergence region. Development of a new algorithm using hemispherical isovelocity surfaces guided by a centerline velocity/distance function in an in vitro study. J Am Coll Cardiol 1994;239A.

45. Shiota T, Shandas R, Moises V, Elkadi T, Golebiovski P, Mrosko B, Sahn DJ. The changing shape of the flow convergence region as a function of orifice size: Color Doppler, laser induced fluorescent particle studies and soap-film observations in an in-vitro model. J Am Coll Cardiol 1994;240A.

46. Sahn DJ, Shiota T, Rice MJ, Reller MD, DeGroff C, Droukas P, Omoto R, Kyo S, Matsumura M, Pantely G, Arai A. A new low cost, versatile intravascular imaging system provides high quality studies with substantially reduced cost of catheters for the patient. J Am Coll Cardiol 1994;241A.

47. Shiota T, Teien D, Jones M, Yamada I, Fry P, Passafini A, Sahn DJ. Evaluation of mitral regurgitation murmurs using a new digital heart sound recording method with real time spectral analysis: Studies in an animal model with quantifiable mitral regurgitation. J Am Coll Cardiol 1994;292A.

48. Shiota T, Shandas R, Golebiovski P, Sahn DJ. New color Doppler techniques for demonstrating free vortices and radial vortex shedding: An in vitro study. J Am Coll Cardiol 1994;309A.

49. Shandas R, Jones M, Shiota T, Yamada I, Teien D, Sahn DJ. A computerized method for calculating cardiac output based on real time color Doppler images using the proximal flow convergence technique: Experimental studies in an animal mode. J Am Coll Cardiol 1994;409A.

50. Kenny A, Sahn DJ, Shiota T, Passafini A, Pantely G, Arai , Jones M, Ge S, Yamada I, Reller MD. A new phase shift echo contrast agent: EchoGen  ; (Sonus Pharmaceuticals) becomes a gas in blood to produce left heart and quantifiable myocardial contrast after venous injection. Studies in sheep and monkeys. J Am Coll Cardiol 1994;450A.

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51. Kenny A, Shiota T, Passafini A, Pantely G, Arai A, Ge S, Hall A, Reller M, Sahn DJ. Quantifiable myocardial and left heart opacification after intravenous injection of a new phase shift echo contrast agent. Ultrasound in Med & Biol 1994, Vol. 20, Suppl. 1:4-5-5; S110.

52. Qian YQ, Sahn DJ, Shiota T. The evaluation of intraoperative transesophageal echocardiography during Fontan operation in children. Ultrasound in Med & Biol 1994, Vol. 20, Suppl.1:4-8-6; S116.

53. Shiota T, Sahn DJ, Ge S, Gong Z, Xu J, Klas B. Three-dimensional reconstruction of color Doppler flow convergence regions and regurgitant jets: An in vitro study. Circulation 1994;90:I-382.

54. Teien D, Jones M, Shiota T, Yamada I. Left ventricular stroke work in mitral regurgitation: An animal study. Circulation 1994;90:I-494.

55. Grauer S, Pantely GA, Xu J, Shiota T, Gong Z, Giraud GG, Reller MD, Sahn DJ. Aerosomes® MRX 115: Echocardiographic and hemodynamic characteristics of a new echo contrast agent that produces myocardial opacification after intravenous injection in pigs. Circulation 1994;90:I-556.

56. Gharib M, Rambod E, Shiota T, Dalton N, Hershberger, Passafini A, Sahn DJ. Vortical structures in cardiac filling flows: A universal descriptor of diastolic efficiency. In vitro and clinical studies. Circulation 1994;90:I-599.

57. Silberbach GM, Shiota T, Kenny A, Klas B, Klein P, Harrison B, Derman R, DeGroff C, McDonald RW, Marcell CP, Sahn DJ. Three-dimensional reconstruction of transthoracic echos in congenital heart disease: "Unroofed" views from surgeon's orientation yield information unobtainable from 2D images. Pediatr Res 1994;35:42A

58. Sinclair B, Shiota T, Ge S, Klas B, Derman R, Sahn DJ. Dynamic three- dimensional reconstruction of flow acceleration towards regurgitant orifices in a pulsatile flow model. J Am Coll Cardiol 1995;85A.

59. Baars MJH, Aaftink DK, Passafini A, Kenny A, Shiota T, Sahn DJ. Evaluation of regurgitant jets by sound intensity using a pulsatile flow model: Potential contribution of regurgitant volume and Reynolds number. J Am Coll Cardiol 1995;191A.

60. Xu J, Pantely GA, Ge S, Grauer S, Shiota T, Gong Z, Zhou X, Sahn DJ. Contrast echocardiographic assessment of myocardial perfusion following acute coronary artery occlusion and reperfusion using intravenous injection of Aerosomes MRX15 in monkeys. J Am Coll Cardiol 1995;204A.

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61. Ge S, Giraud GD, Shiota T, Pantely GA, Xu J, Gong Z, Zhou X, Hall A, Sahn DJ. Microcirculatory flow dynamics during peripheral intravenous injection of Echogen : Microscopic visualization of mesenteric microcirculatory flow with simultaneous transthoracic echo imaging in cats. J Am Coll Cardiol 1995;227A.

62. Ge S, Shiota T, Duwelius PJ, Ellichman JJ, Gong Z, XU J, Holcomb S, Ishii M, Hall AS, Sahn DJ. Ultrasonic monitoring of fat embolization during major orthopedic procedures: Experimental studies in sheep define a new utility for intracardiac ultrasound. J Am Coll Cardiol 1995;353A.

63. Ishii M, Jones M, Shiota T, Yamada I, Heinrich RS, Yoganathan AP, Sahn DJ. Quantitative evaluation of aortic regurgitant stroke volume using vena contracta imaging by color Doppler and continuous wave Doppler echocardiography: An animal study with quantified . J Am Coll Cardiol 1995;379A.

64. Shiota T, Jones M, Heinrich RS, Ishii M, Yamada I, Yoganathan AP, Sinclair B, Ge S, Sahn DJ. Dynamic changes in aortic regurgitant orifice area: A chronic animal model study. J Am Coll Cardiol 1995;379A.

65. Ge S, Jones M, Shiota T, Yamada I, Valdes-Cruz LM, Shandas R, Sahn DJ. Determination of flow rate and orifice area in mitral stenosis by Doppler color flow imaging: Quantitative application of centerline velocity/distance function of proximal flow field. J Am Coll Cardiol 1995;379A.

66. Gong Z, Zhou X, Shiota T, Sinclair B, Ge S, Xu J, Klas B, Derman R, Sahn DJ. Comparison between three-dimensional reconstruction and two-dimensional imaging for evaluating regurgitant jets: An in vitro study. J Am Coll Cardiol 1995;380A.

67. Yamada I, Shiota T, Heinrich RS, Ishii M, Yoganathan A, Sahn DJ, Jones M. Evaluation of aortic regurgitation (AR) using color Doppler measurement: An animal study with quantified AR. J Am Coll Cardiol 1995;397A.

68. Shiota T, Jones M, Heinrich RS, Yamada I, Yoganathan AP, Sahn DJ. Evaluation of aortic regurgitation using digitally determined color Doppler imaged flow convergence acceleration: A quantitative study in animals. J Am Coll Cardiol 1995;397A.

69. DeGroff CG, Baptista AM, Shiota T, Cable J, Foster L, Sahn DJ. A flow convergence method to quantitate regurgitant flow with a flail mitral valve leaflet: Finite element modeling and experimental studies. J Am Coll Cardiol 1995;398A.

70. Ge S, Jones M, Shiota T, Heinrich RS. Validity of flow convergence methods for assessment of aortic regurgitation in a chronic animal model with quantifiable regurgitation. Circulation 1995;92:I-722.

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71. Zhou X, Delabays A, Shiota T, Teien D, Ge S, Gong Z, Ishii M, Pandian NG. Effects of orifice shape, Nyquist limit and adjacent surfaces on three-dimensionally reconstructed color Doppler regurgitant jets: An in vitro study. Circulation 1995;92:I-722.

72. Shiota T, Jones M, Delabays A, Derman R, Yamada I, Sahn DJ, Pandian NG. 3D reconstruction of flow convergence and jets in aortic regurgitation: A chronic animal model study. Circulation 1995;92:I-797.

73. Shiota T, Delabays A, Teien D, Sinclair BG, Pandian NG, Sahn DJ, Klas B. Three- dimensional reconstruction of color Doppler flow convergence regions for aortic and mitral regurgitation: An in vitro study. Circulation 1995;92:I-797.

74. Delabays A, Shiota T, Teien D, Ge S, Sahn DJ, Pandian NG. Three-dimensional echocardiography allows accurate quantitation of the vena contracta and mitral regurgitation flow rates for asymmetric orifices: An in vitro validation study. Circulation 1995;92:I-798.

75. Walker KW, Ge J, Grauer S, Pantely GA, Giraud GD, Shiota T, Ishii M, Powers J, Sahn DJ. Echocardiographic imaging of myocardial opacification with second harmonic imaging of peripherally injected Aerosome® echocontrast yields improved quantitation. J Am Coll Cardiol 1996;27:128A.

76. Harada K, Shiota T, Ishii M, Rice MJ, McDonald RW, Sahn DJ. Maternal administration of indomethacin and premature constriction of the ductus arteriosus in the human fetus. J Am Coll Cardiol 1996;27:158A.

77. Sinclair BG, Marx GR, Shiota T, Pandian NG, Sahn DJ. Three-dimensional reconstruction of color Doppler flow images in congenital heart disease. J Am Coll Cardiol 1996;27:158A.

78. Zhou X, Jones M, Shiota T, Teien D, Ge S, Ishii M, Sahn DJ. Assessment of left ventricular relaxation by continuous-wave Doppler echocardiography: Accuracy of measurement of the time constant Tau: An animal study. J Am Coll Cardiol 1996;27:173A.

79. Ge S, Yamada I, Shiota T, Jones M, Teien D, Sahn DJ. Quantitation of chronic mitral regurgitation using the flow convergence method: Impact of selection of aliasing velocity and distance of the isovelocity surface from the regurgitant orifice: Studies in a chronic animal model. J Am Coll Cardiol 1996;27:238A.

80. Foster L, Shiota T, Sahn DJ. Optimal methods for quantifying mitral regurgitation using the flow convergence method in prolapsed mitral valves: An in vitro study. J Am Coll Cardiol 1996;27:239A,.

51

81. Ishii M, Shiota T, Zhou X, Sinclair BG, Sahn DJ. Effect of imaging angle on the color Doppler imaged vena contracta: An in vitro study. J Am Coll Cardiol 1996;27:239A.

82. Ishii M, Jones M, Shiota T, Yamada I, Heinrich R, Yoganathan AP, Sahn DJ. Limitations of continuous wave Doppler grading in aortic regurgitation: A chronic animal model. J Am Coll Cardiol 1996;27:239A.

83. Sandhu SK, Reller MD, Sharma S, Shiota T, Ishii M, Ren BQ, Sahn DJ. Assessment of pulmonary artery stenosis using the “lesion molding catheter”. J Am Coll Cardiol 1996;27:262A.

84. Sahn DJ, Shiota T, Zhou X, Aida S, Ishii M, Pandian NG. Use of three-dimensional reconstruction for understanding and quantifying surface adherent regurgitant jets: An in vitro study. J Am Coll Cardiol 1996;27:268A.

85. Aida S, Shiota T, Tsujino H, Sahn DJ. Automated calculation of aortic regurgitant volume by a newly developed digital Doppler color flow mapping method: An in vitro study. J Am Coll Cardiol 1996;27:269A.

86. Shiota T, Jones M, Tsujino H, Yamada I, Aida S, Delabays A, Pandian NG, Sahn DJ. Automated calculation of aortic regurgitant volume and regurgitant fractions by a newly developed digital Doppler color flow mapping method: An animal study. J Am Coll Cardiol 1996;27:269A.

87. Ishii M, Jones M, Shiota T, Yamada I, Heinrich RS, Yoganathan AP, Sahn DJ. Quantifying aortic regurgitation by vena contracta imaging: A chronic animal model study. J Am Coll Cardiol 1996;27:284A.

88. Zhou X, Shiota T, Jones M, Yamada I, Teien D, Sahn DJ. Vena contracta imaging by Doppler color flow mapping predicts severity of mitral regurgitation: An animal study. J Am Coll Cardiol 1996;27:284A.

89. Xu J, Shiota T, Ge S, Gong Z, Rice MJ, Sahn DJ. Aortic distensibility in aortic coarctation using intravascular ultrasound (IVUS). J Am Coll Cardiol 1996;27:336A.

90. Shiota T, Sahn DJ, Cobanoglu A, Casson H, Ge S, Sandhu SK, Omoto R, Kyo S. Applicability of transesophageal imaging of the flow convergence region for evaluating patent ductus arteriosus. J Am Coll Cardiol 1996;27:350A.

91. Heinrich RS, Jones M, Yamada I, McGhee J, Shiota T, Yoganathan AP. The jet centerline velocity decay method for noninvasive calculation of aortic regurgitant volume. J Am Coll Cardiol 1996;27:395A.

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92. Harada K, Rice MJ, Shiota T, McDonald RW, Sahn DJ. Effect of ventricular wall mass on Doppler filling patterns in the developing normal human heart. Circulation 1996;I-236.

93. Shiota T, Jones M, Aida S, Thigpen T, Chikada M, Yamada I, Sahn DJ. Calculation of shunt flow volume through atrial septal defects by a newly developed digital color Doppler flow quantitation method: In vitro and experimental animal study in sheep. Circulation 1996;I-416.

94. Walker KW, Grauer SE, Giraud GD, Shiota T, Kerkhof E, Speleman M, Sahn, DJ, Pantely GA. Persistence of echocontrast reflectivity: Effective frequency and delivery parameters. Circulation 1996;I-130.

95. Li XK, Jones M, Shiota T, Delabays A, Yamada I, Pandian NG, Sahn DJ. Direct calculation of 3D flow convergence surface area from 3D color Doppler flow maps for computing aortic regurgitant flows: A chronic animal study. J Am Coll Cardiol 1997;29:174A.

96. Shiota T, Omoto R, Cobanoglu A, Kyo S, Rice MJ, Sahn DJ. Quantitative analysis of patent ductus arteriosus shunt by transesophageal imaging of the flow convergence region. J Am Coll Cardiol 1997;29:37A.

97. Stock JH, Reller MD, Sharma S, Pavcnik D, Shiota T, Sahn DJ. Trans-balloon intravascular ultrasound during balloon dilation of pulmonary artery stenoses and aortic coarctation. J Am Coll Cardiol 1997;29:145A.

98. Singh G, Shiota T, Sandhu S, Cobanoglu A, Droukas P, Rice MJ, Sahn DJ. Special role of transesophageal echo (TEE) in surgery for congenital left ventricular outflow tract (LVOT) obstruction. J Am Coll Cardiol 1997;29:509A.

99. pulmonary venous flow direction on color Doppler flow mapping of mitral regurgitation: An in Griever G, Shiota T, Passafini A, Sahn DJ, Manrique F. Impact of jet orientation and vitro study with optical dye correlations. J Am Coll Cardiol 1997;29:518A.

100. Shiota T, Jones M, Ota T, Chikada M, Fleishman CE, Kisslo J, Cotter B, Ryan TJ, DeMaria AN, von Ramm OT, Sahn DJ. Application of a new real-time three- dimensional method for evaluating right ventricular stroke volume. Circulation 1997;I-328.

101. Ota T, Jones M, Fleishman CE, Shiota T, Zetta AD, Cotter B, DeMaria AN, Sahn DJ, Ryan TJ, von Ramm. OT, Kisslo J. Accuracy of left ventricular stroke volume measurement using real-time, three dimensional echocardiography and electromagnetic flow probe in vivo. Circulation 1997;I-328.

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102. Li XK, Shiota T, Martin RW, Sahn DJ, Schwartz GA, Park Y, Munt BI, Detmer PR, Sheehan FH, Otto CM. Digital three dimensional Doppler flow mapping: a new modality in echocardiography. Circulation 1997;I-329.

103. Wanitkun S, Shiota T, Irvine T, Li XK, Park Y, Kenny A, Sahn DJ. Evaluation of flow volumes through compliant pulsatile vessels with dynamically changing flow area: advantages of a semi-automated color Doppler flow measurement methods: An in vitro pulsatile flow study. Circulation 1997;I-512.

104. Irvine T, Shiota T, Wanitkun S, Kenny A, Sahn DJ. Acoustic-stimulated transient power scattering explains enhanced detection of the very low velocities in myocardial capillaries by power Doppler imaging: An in vivo study. Circulation 1997;I-585.

105. Park Y, Shiota T, Munt BI, Wanitkun S, Li XK, Otto CM, Sheehan FH, Martin RW, Sahn DJ. Does orifice shape effect color Doppler jet shape, vena contracta and jet volume? An in vitro digital 3D reconstruction study. Circulation 1997;I-749.

106. Wanitkun S, Shiota T, Giraud GD. Axial centerline proximal flow convergence method for evaluation of aortic coarctation: An in vitro study. Circulation 1997;I- 511.

107. Shiota T, Greenberg NL, Sun JP, Quin JX, Cardon LA, Morehead AJ, Cosgrove DM, Stewart WJ, Thomas JD. Real-time 3-dimensional Echocardiography and semi- automated digital Doppler color flow mapping for evaluating mitral regurgitation. J Am Soc Echocardiogr 1998; 11:560.

108. Shiota T, McCarthy PM, Wong J, Greenberg NL, Thomas JD. Value of real-time intraoperative 3-dimensional Echocardiography in patients undergoing surgery for dilated cardiomyopathy. J Am Soc Echocardiogr 1998.

109. Shiota T, White RD, Flamm S, McCarthy PM, Greenberg NL, Sun JP, Qin JX, Odabashian J, Morehead AJ, Thomas JD. Real-time 3-dimensional Echocardiography for assessing left ventricular volume and ejection fraction in patients with dilated cardiomyopathy: Comparison with magnetic resonance imaging (MRI). J Am Soc Echocardiogr 1998; 11:560.

110. Shiota T, Smith LS, Lewandowski R, Piel JE, Lancee C, Djoa K, Sahn DJ. Special capabilities of micro-multiplane transesophageal echocardiography for studying congenital heart disease surgery in neonates, infant and children. J Am Coll Cardiol 1998;247A.

111. Shiota T, Jones M, Ota T, Chikada M, Castellucci JB, von Ramm OT, Kisslo J, Ryan TJ, Sahn DJ. Real time 3D echocardiography for assessing the atrial septal

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defect size and shunting: quantitative studies in a chronic animal model. J Am Coll Cardiol 1998;259A.

112. Li XK, Jones M, Shiota T, Delabays A, Sahn DJ. Lack of dynamic change in effective aortic regurgitant orifice area measured by direct flow convergence surface area from 3D flow images: A chronic animal study. J Am Coll Cardiol 1998, 298A.

113. Shiota T, Sinclair BG, Gharib M, Rambod E, Sahn DJ. Radial jet vortical events are better delineated on 3D reconstructions of flow images than on 2D color Doppler: An in vitro study with comparisons to optical visualization of flow jets. J Am Coll Cardiol 1998, 338A.

114. Li XK, Ge S, Shiota T, Listerud J, Zhou X, Sahn DJ. Phase contrast magnetic resonance imaging of effective orifice area for restrictive valve orifices. J Am Coll Cardiol 1998, 340A.

115. Ishii M, Shiota T, Thigpen T, Sinclair BG, Aida S, Ge S, Sahn DJ. Improved high frequency ultrasound imaging of chick embryo hearts for studies of chamber growth and function: Additional utility of 3D sweep power mode imaging. J Am Coll Cardiol 1998, 466A.

116. Li XK, Shiota T, Park YB, Munt B, Wanitkin S, Martin RW, Sahn DJ, Schwartz GA, Otto CM, Sheehan FH. A digital three-dimensional color Doppler velocity reconstruction study of the relationship between orifice shape and flow convergence geometry: In vitro experiments. J Am Coll Cardiol 1998, 517A.

117. Byrd G, Shiota T, Wanitkin S, Young A, Martin S, Sahn DJ. Advantages of a digital coor Doppler method for computing flow in highly pulsatile vessels. J Am Coll Cardiol 1998, 517A.

118. Shiota T, Jones M, Agler DA, Cardon LA, Greenberg NL, Zetts AD, Thomas JD. A quantitative evaluation of aortic regurgitant volume using color Doppler flow convergence and vena contracta imaging from right parasternal window: A clinical and chronic animal study. Circulation 1998; 98: I-786.

119. Qin JX, Jones M, Greenberg NL, Shiota T, Cardon LA, Zetts AD, Thomas JD. Estimation of left ventricular function by real-time 3-dimensional echocardiography and conductance catheterization: An animal study with chronic aortic regurgitation. Circulation 1998;98:I-357.

120. Shiota T, Jones M, Zetts A, Cardon LA Greenberg NL, Thomas JD. Real-time 3- dimensional contrast echocardiography for visualizing and quantifying left ventricular inflow phenomena: Comparison with Doppler method. Circulation 1998; 98:I-226.

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121. Qin JX, Jones M, Shiota T, Greenberg NL, Cardon LA, Zetts AD, Thomas JD. Comparison of the left ventricular volume estimation between real-time 3D and 2D echo: An animal study with/without LAD occlusion. Computers in Cardiology 1998; 173.

122. Qin JX, Shiota T, Sun JP, Odabashian JA, White RD, Flamm SD, Thomas JD. A new digital method for estimating left ventricular volume using real-time 3D echocardiography: A comparison with magnetic resonance imaging. J Am Coll Cardiol 1999; 33: 441A

123. Qin JX, Jones M, Shiota T, Zetts AD, Greenberg NL, Cardon LA, Panza JA, Thomas JD. Accurate measurement of left ventricular stroke volumes using real- time, 3D echo during non ischemic and ischemic conditions. J Am Coll Cardiol 1999; 33:486A

124. Qin JX, Jones M, Shiota T, Morehead AJ, Tsujino H, Zetts AD, Greenberg NL, Cardon LA, Panza JA, Thomas JD. Real-time three-dimensional contrast echocardiography for left ventricular cavity visualization: Animal and clinical studies. J Am Coll Cardiol 1999; 33: 431A

125. Shiota T, Garcia MJ, Qin JX, Drinko J, Armstrong G, Greenberg NL, Thomas JD. Detection of exact locations of cardiac catheters using real-time 3-dimensional echocardiography. J Am Coll Cardiol 1999; 33: 486A.

126. Shiota T, Jones M, Tsujino H, Qin JX, Zetts A, Greenberg N, Cardon LA, Panza JA, Thomas JD. Real-time 3-dimensional echocardiography and semi-automated digital Doppler color flow mapping for evaluating stroke volume and aortic regurgitant volume. J Am Coll Cardiol 1999; 33: 441A.

127. Shiota T, Stewart WJ, Qin JX, McCarthy PM, Wong J, Cosgrove DM, Thomas JD. Initial experience with real-time 3-dimensional echocardiography for the mitral valve apparatus. J Am Coll Cardiol 1999; 33:404A.

128. Qin JX, Jones M, Shiota T, Morehead AJ, Tsujino H, Zetts A, Greenberg N, Cardon LA, Panza JA, Thomas JD. Real-time 3-dimensional contrast echocardiography for left ventricular cavity visualization: An animal study. J Am Coll Cardiol 1999; 33: 431A.

129. Qin JX, Shiota T, Sun JP, Odabashian JA, White RD, Flamm SD, Thomas JD. A new digital method for estimating left ventricular volume using real-time 3D echocardiography: A comparison with magnetic resonance imaging. J Am Coll Cardiol 1999; 33: 441A.

130. Qin JX, Jones M, Shiota T, Zetts AD, Greenberg NL, Cardon LA, Panza JA, Thomas JD. Accurate measurement of left ventricular stroke volumes using real-

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time, 3D echo during non-ischemic and ischemic conditions. J Am Coll Cardiol 1999; 33: 486A.

131. Hazard CR, Shiota T, Qin JX, Tsujino H, Thomas JD. Real-time three-dimensional echocardiography determination of flow velocity: A comparison with Doppler technique. J Am Soc Echocardiogr 1999;12: 361.

132. Tsujino H, Jones M, Shiota T, Huskey KD, Qin JX, Travaglini A, Zetts A, Greenberg NL, Cardon LA, Panza JA, Thomas JD. Left ventricular stroke work in aortic regurgitation: an animal study using conductance catheter and real-time 3D echocardiography. J Am Soc Echocardiogr 1999;12: 370.

133. Tsujino H, Shiota T, Qin JX, Greenberg NL, Flachkampf FA, Thomas JD. Assessment of the mitral annular motion using real-time 3D echocardiography: A clinical study. J Am Soc Echocardiogr 1999;12: 402.

134. Qin JX, Jones M, Shiota T, Tsujino H, Greenberg NL, Zetts AD, Cardon LA, Panza JA, Thomas JD. Value of real-time 3D echo and semi-automated digital Doppler color flow mapping during different LV loading conditions in aortic regurgitation. J Am Soc Echocardiogr 1999;12: 372.

135. Qin JX, Jones M, Shiota T, Tsujino H, Greenberg NL, Zetts A, Cardon LA, Drinko JK, Panza JA, Thomas JD. Left ventricular stroke volume determined by real-time 3D echo in animals with LV aneurysms: Comparisons with 2D echo and angiography. J Am Soc Echocardiogr 1999;12: 362.

136. Qin JX, Shiota T, Lever H, Rubin D, Yalcin F, Drinko JK, Agler DA, Thomas JD. Left ventricular outflow tract area measured by real-time 3D echocardiography in hypertrophic obstructive cardiomyopathy. J Am Soc Echocardiogr 1999; 12(5):381.

137. Qin JX, Shiota T, Tsujino H, Greenberg NL, Flachkampf FA, Gillinov MA, Stewart WJ, Cosgrove DM, Thomas JD. Cosgrove-Edwards mitral ring movement determined by real-time 3D echocardiography (3DE): A five years follow up study. J Am Soc Echocardiogr 1999;12: 348.

138. Qin JX, Shiota T, Tsujino H, Greenberg NL, Xu Y, Sun JP, Odabashian JA, White RD, Stewart WJ, Thomas JD. Geometry and motion of the mitral annulus assessed by real-time 3D echocardiography: A comparison with MRI. J Am Soc Echocardiogr 1999;12: 379.

139. Firstenberg M, Cardon LA, Greenberg NL, Garcia MJ, Qin JX, Bauer F, Travaglin A, Shiota T, Thomas JD. Changes in diastolic intraventricular pressure gradients, geometry, and volume with acute postural changes. Eur J Echocardiogr 1999; S68.

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140. Cardon LA, Firstenberg M, Greenberg NL, Garcia MJ, Shiota T, Qin JX, Tsujino H, Mariwaha VR, Thomas JD. Real-time three-dimensional assessment of total cardiac volume and the ratio of chamber specific volumes. Eur J Echocardiogr 1999; S86.

141. Tsujino H, Jones M, Shiota T, Qin JX, Cardon LA, Morehead AJ, Travaglini A, Bauer F, Zetts AD, Greenberg NL, Panza JA, Thomas JD. Estimation of the spatial mean and peak flow velocities using real-time 3D color Doppler echocardiography. Computers in Cardiology 1999; 45.

142. Bauer F, Shiota T, Qin JX, Tsujino H, Travaglini A, Marwaha VR. Change in left atrial function during acute coronary occlusion: A pressure-volume loop analysis. Circulation 1999;100(18): I-572.

143. Qin JX, McCarthy PM, Shiota T, Firstenberg MS, Smedira NG, Hoercher K, Buda T, Tsujino H. Real time 3D echocardiographic study of left ventricular function after infarct exclusion surgery. Circulation 1999; 100(18): I-167.

144. Han P, Shiota T, Tsujino H, McCarthy PM, Qin JX, Bauer F, Travaglini A, Firstenberg M, Thomas JD. Assessment of aortic annular motion in patients with ischemic cardiomyopathy by real-time 3D Echocardiography (RT3DE) before and after the infarct exclusion procedure. J Am Coll Cardiol 2000;35:460A.

145. Bauer F, Jones M, Shiota T, Qin JX, Tsujino H, Travaglini A, Zetts AD, Panza JA, Thomas JD. Assessment of left atrial end-systolic pressure volume relationship in an animal model: A real-time 3D echocardiographic and hemodynamic. J Am Coll Cardiol 2000;35: 471A.

146. Qin JX, Shiota T, Lever HM, Rubin DN, Bauer F, Tsujino H, Drinko JK, Martin MG, Thomas JD. Comparison of percutaneous transluminal septal myocardial ablation and septal myectomy in hypertrophic obstuctive cardiomyopathy. J Am Coll Cardiol 2000;35:191A.

147. Camarano G, Jones M, Shiota T, Ernst I,. Zetts AD, Thomas JD, Panza JA. Effect of remodeling following myocardial infarction on left ventricular size and function: A real-time 3-dimensional echocardiographic study. J Am Coll Cardiol 2000;35:443A.

148. Tsujino H, Shiota T, Qin JX, Bauer F, Travaglini A, Greenberg NL, Thomas JD. Estimation of the spatial mean and peak flow velocities using real-time 3D (RT3D) color Doppler echocardiography: An in vitro experiment. J Am Coll Cardiol 2000;35:436A.

149. Bauer F, Jones M, Shiota T, Qin JX, Tsujino H, Morehead AJ, Cardon LA, Travaglini A, Zetts AD, Panza JA, Thomas JD. Left atrial contractile function during

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left ventricular ischemia with and without left atrial ischemia. J Am Coll Cardiol 2000;35:458A.

150. Bauer F, Jones M, Shiota T, Qin JX, Tsujino H, Travaglini A, ZettsAD, Panza JA, Thomas JD. Left atrial volume and function: Relationship to left ventricular function. J Am Coll Cardiol 2000;35:494A.

151. Bauer F, Shiota T, White R, Qin JX, Travaglini A, Tsujino H, Thomas JD. Left atrial volume measurement by real-time 3D Echocardiography. J Am Coll Cardiol 2000;35:437A.

152. Travaglini A, Jones M, Shiota T, Qin JX, Bauer F, Tsujino H, Cardon LA, Morehead AJ, Greenberg NL, Panza JA, Zetts AD, Thomas JD. Measurement of left ventricular mass (LVM) using real-time 3D and 2D echocardiography in chronic animal model. J Am Coll Cardiol 2000;35:468A.

153. Tsujino H, Jones M, Shiota T, Qin JX, Cardon LA, Morehead AJ, Zetts AD, Bauer F, Travaglini A, Greenberg NL, Panza JA, Thomas JD. Quantification of the volumetric flow rate using real-time 3D (RT3D) color Doppler echocardiography: An animal study. J Am Coll Cardiol 2000;35:461A.

154. Tsujino H, Jones M, Shiota T, Qin JX, Cardon LA, Morehead AJ, Zetts AD, Bauer F, Travaglini A, Greenberg NL, Panza JA, Thomas JD. Real-time 3D color Doppler echocardiography for analysis of the spatial velocity distribution in the left ventricular outflow tract. J Am Coll Cardiol 2000;335:436A.

155. Qin JX, Jones M, Shiota T, Tsujino H, Travaglini A, Zetts AD, Cardon LA, Morehead AJ, Bauer F, Thomas JD. Real-time 3D pulsed wave (PW) Doppler echocardiography for quantification of the left ventricular stroke volume. J Am Coll Cardiol 2000;35:442A.

156. Qin JX, Shiota T, Tsujino H, Firstenberg MS, Cardon LA, Odabashian JA, White RD, Thomas JD. Validation of Real-time 3D Echocardiography for Quantifying LV Volumes in the Presence of a LV Aneurysm. In Vitro and Clinical Studies. J Am Coll Cardiol 2000;35:186A.

157. Agler DA, Shiota T, Tsujino H, Qin JX, Travaglini A, Bauer F, Cosgrove DM, Stewart WJ, Thomas JD. Real-time color 3D echo Doppler improves spatial localization of mitral prolapse for flail. Operative validation. J Am Soc Echocardiogr 2000;13(5):430.

158. Bauer F, Jones M. Shiota T, Qin JX, Tsujino H. Travaglini A. Wantanabe J, Zetts AD, Thomas JD. Left ventricular outflow tract systolic acceleration for quantifying left ventricular contractility. J Am Soc Echocardiogr 2000;13(5):433.

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159. Bauer F, Shiota T, Lever HM, Qin JX, Travaglini A, Tsujino H. Thomas JD. Determinants of left atrial dilatation in patients with hypertrophic cardiomyopathy. J Am Soc Echocardiogr 2000;13(5):467.

160. Bauer F, Shiota T, Qin JX, Tsujino H, Travaglini A. Thomas JD. Left atrial volume determined by real-time 3D echocardiography in patients with mitral regurgitation. J Am Soc Echocardiogr 2000;13(5):502.

161. Cardon LA, Firstenberg MS, Greenberg NL, Shiota T, Qin JX, Tsujino H, Garcia MJ, Thomas JD. Relationship between chamber specific volumes to total cardiac volume: A real-time 3D echo study. J Am Soc Echocardiogr 2000;13(5):440.

162. Firstenberg MS, Greenberg NL, Smedira NG, Prior DL, Shiota T, Qin JX, McCarthy PM, Tsujino H, Hoercher K, Buda T, Garcia MJ, Thomas JD. Effects of surgical on systolic and diastolic function: An intra-operative physiologic and real-time 3D echo study. J Am Soc Echocardiogr 2000;13(5):470.

163. Qin JX, Shiota T, McCarthy PM, Tsujino H, Bauer F, Travaglini A, Thomas JD. Improvement of LV function determined by real-time 3D echo after infarct excision with simultaneous mitral valve repair in ischemic cardiomyopathy patients with mitral regurgitation. J Am Soc Echocardiogr 2000;13(5):467.

164. Qin JX, Shiota T, Tsujino H. Agler DA, Bauer F, Travaglini A, Gillinov MA, Stewart WJ, Cosgrove DM, Thomas JD. Transmitral inflow pattern and annulus geometry before and after mitral valve repair in patients with mitral regurgitation: A clinical real-time 3D echocardiographic study. J Am Soc Echocardiogr 2000;13(5):501.

165. Qin JX, Shiota T, Tsujino H, Greenberg NL, Odabashian JA, White RD, Stewart WJ, Thomas JD. Size and motion of mitral annulus assessed by real-time 3D echo in different cardiac diseases: Comparison with MRI. J Am Soc Echocardiogr 2000;13(5):490.

166. Travaglini A, Jones M, Shiota T, Bauer F, Tsujino H, Qin JX, Wantanabe J, Greenberg NL, Zetts AD, Thomas JD. Relationship between ejection fraction and contractility index (Emax) in chronic aortic regurgitation: Conductance catheter and real-time 3D echo study in animals. J Am Soc Echocardiogr 2000;13(5):501.

167. Travaglini A, Shiota T, Tsujino H, Bauer F, Qin JX, Greenberg NL, Thomas JD. Accuracy of the “left ventricular” volume determination using real-time 3D echocardiography: An in vitro study. J Am Soc Echocardiogr 2000;13(5):489.

168. Tsujino H, Jones M, Shiota T, Qin JX, Cardon LA, Morehead AJ, Zetts AD, Bauer F, Greenberg NL, Thomas JD. Contrast enhanced harmonic imaging of myocardial

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perfusion in acute and chronic myocardial infarction: An animal experiment. J Am Soc Echocardiogr 2000;13(5):459.

169. Tsujino H, Jones M, Shiota T, Qin JX, Cardon LA, Morehead AJ, Zetts AD, Bauer F, Travaglini A, Watanabe J, Greenberg NL, Thomas JD. Assessment of the geometry and dynamic motion of the mitral annulus during coronary artery occlusion: A real-time 3D echocardiographic study. J Am Soc Echocardiogr 2000;13(5):478.

170. Tsujino H, Shiota T, Qin JX, Agler DA, Bauer F, Gillinov MA, Cosgrove DM, Stewart WJ, Thomas JD. Quantitative assessment of the mitral annular motion in mitral regurgitation: A color-encoded 2D tissue Doppler imaging study. J Am Soc Echocardiogr 2000;13(5):473.

171. Watanabe J, Jones M, Shiota T, Garcia MJ, Tsujino H, Bauer F, Qin JX, Travaglini A, Thomas JD. Color M-mode Doppler flow propagation of late diastolic velocity during preload alteration: An animal study. J Am Soc Echocardiogr 2000;13(5):472.

172. Xu T, Shiota T, Qin JX, Tsujino H. Sun JP, Bauer F, Drinko JK, Bashir M, Stewart WJ, Thomas JD. Left atrial volume and function determined by real-time 3- dimensional echocardiography in cardiac transplant recipients. J Am Soc Echocardiogr 2000;13(5):489.

173. Tsujino H, Shiota T, Qin JX, Agler DA, Bauer F, Travaglini A, Thomas JD. Quantitative digital color Doppler and real-time 3D echocardiography for evaluating aortic and mitral regurgitation. Ultrasound in Med & Biol 2000; 26

174. Marwaha V, Shiota T, Qin JX, Bauer F, Tsujino H, Greenberg NL, Firsteinberg MS, Travagluni A, Thomas JD. Real-time three-dimensional echocardiography for determining left ventricular size and function: comparison with conventional M- mode and two-dimensional echocardiography. J Am Soc Echocardiogr 2000;13(5):490.

175. Qin JX, Shiota T, Firsterberg MS, Sitges M, Bauer F, Travaglini A, Hoercher KJ, Buda T, Smedira NG, McCarthy PM. Efficacy of infarct exclusion surgery in patients with severe left ventricular dysfunction: A real-time 3D echo study. Circulation 2000; 102(18)II-461.

176. Qin JX, Shiota T, Bauer F, Sato M, Wika K, Lee A, Soloviev MV, Lapyre D, Harasaki H. Hemodynamic characteristics of a new tri-leaflet mechanical valve prosthesis in the mitral position in a calf model: A real-time 3D echocardiographic study. Circulation 2000; 102(18)II-649.

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177. Sitges M, Shiota T, Tsujino H, Qin JX, Bauer F, Agler DA, Cardon LA, Panza JA. Real-time three-dimensional color-Doppler evaluation of the flow convergence surface for quantification of mitral regurgitation. Circulation 2000; 102(18)II-629.

178. Sitges M, Jones M, Shiota T, Prior DL, Tsujino H, Cardon LA, Zetts AD, Garcia MJ, Thomas JD. Interaliasing distance of the flow convergence surface for determining mitral regurgitant volume: A validation study in a chronic animal model. Circulation 2000; 102(18)II-474.

179. Bauer F, Shiota T, Qin JX, Tsujino H, Sitges M, Kim YJ, Thomas JD. Feasibility of real-time 3D echocardiography for measuring mitral valve orifice area in normal subjects and in patients with mitral stenosis. J Am Coll Cardiol 2001;37(2):403A.

180. Bauer F, Shiota T, Sitges M, Qin JX, Kim YJ, Tsujino H, Thomas JD. Description of left ventricular Inflow by real-time three-dimensional echocardiography. J Am Coll Cardiol 2001;37(2):408A.

181. Bauer F, Jones M, Shiota T, Firstenberg MS, Qin JX, Tsujino H, Kim YJ, Sitges M, Cardon LA, Zetts AD, Thomas JD. Left ventricular outflow tract mean systolic acceleration as a surrogate of the slope of the left ventricular contractility. J Am Coll Cardiol 2001;37(2):417A.

182. Daugherty DW, Jones M, Shiota T, Teien D, Bauer F, Sitges M, Qin JX, Tsujino H, Zetts AD, Panza JA, Thomas JD. Relationship between the left atrial and left ventricular pressures and pulmonary venous flow velocities in animals with and without mitral regurgitation. J Am Coll Cardiol 2001;37(2):439A.

183. Kim YJ, Jones M, Shiota T, Travaglini A, Bauer F, Tsujino H, Qin JX, Sitges M, Cardon LA, Zetts AD, Thomas JD. Is ejection fraction a reliable marker of left ventricular contractility?: Comparison with Emax in chronic animal models with load alterations. J Am Coll Cardiol 2001;37(2):388A.

184. Kim YJ, Jones M, Shiota T, Tsujino H, Qin JX, Bauer F, Sitges M, Cardon LA, Zetts AD, Thomas JD. Change of pressure half time with acute alterations of preload and afterload in chronic aortic regurgitation. J Am Coll Cardiol 2001;37(2):417A.

185. Qin JX, Shiota T, McCarthy PM, Greenberg NL, Bauer F, Sitges M, Drinko JK, Hang XY, Kim YJ, Hoercher KJ, Buda T, Smedira NG, Thomas JD. Real-time three-dimensional echocardiographic follow-up of patients with ischemic cardiomyopathy undergoing infarct exclusion surgery. J Am Coll Cardiol 2001;37(2):331A.

186. Qin JX, Shiota T, Sitges M, Wang K, Zhou Z, Zhou X, Hang XY, Kim YJ, Bauer F, Greenberg NL, Thomas JD. Serial changes of left ventricular function in dogs

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following myocardial ischemia-reperfusion injury: A real-time 3-dimensional echocardiographic assessment. J Am Coll Cardiol 2001;37(2):427A.

187. Qin JX, Shiota T, Takagaki M, Cardon LA, Ochiai Y, Tabata T, McCarthy PM, Schweich CJ, Mortier TJ, Schroeder RF, Thomas JD. Changes in left ventricular shape and cavity area after myocardial splinting in a cardiomyopathy dog model: A real-time 3-dimensional echocardiographic study. J Am Coll Cardiol 2001;37(2):142A.

188. Sitges M, Jones M, Shiota T, Caden DM, Qin JX, Tsujino H, Bauer F, Kim YJ, Cardon LA, Martin MG, Zetts AD, Panza JA, McCarthy PM, Thomas JD. Real-time three-dimensional echocardiography and cine-ventriculography for determining left ventricular volumes in the presence of left ventricular aneurysms. J Am Coll Cardiol 2001;37(2):425A.

189. Sitges M, Shiota T, Qin JX, Kim YJ, Bauer F, Wang K, Zhou Z, Zhou X, Greenberg NL, Garcia MJ, Thomas JD. Non-invasive assessment of serial changes in left ventricular diastolic function during myocardial ischemia-reperfusion. J Am Coll Cardiol 2001;37(2):438A.

190. Sitges M, Shiota T, Lever HM, Qin JX, Bauer F, Drinko JK, Agler DA, Martin MG, Smedira, NG, Lytle BW, Kapadia SR, Tuzcu EM, Garcia MJ, Thomas JD. Improved diastolic function after septal reduction in obstructive hypertrophic cardiomyopathy. J Am Coll Cardiol 2001;37(2):200A.

191. Sitges M, Shiota T, Lever HM, Qin JX, Bauer F, Tsujino H, Kim YJ, Drinko JK, Agler DA, Kapadia SR, Tuzcu EM, Smedira NG, Lytle BW, Thomas JD. Evaluation of left ventricular outflow tract area after septal reduction in hypertrophic obstructive cardiomyopathy: A real-time three-dimensional echocardiographic study. J Am Coll Cardiol 2001;37(2):200A.

192. Tsujino H, Jones M, Shiota T, Kim YJ, Bauer F, Qin JX, Sitges M, Cardon LA, Zetts AD, Thomas JD. Influence of loading conditions on physical determinants of aortic regurgitant flow volume and severity: A chronic animal experiment. J Am Coll Cardiol 2001;37(2):485A.

193. Tsujino H, Jones M, Shiota T, Qin JX, Cardon LA, Morehead AJ, Zetts AD, Bauer F, Hang X, Greenberg NL, Panza JA, Thomas JD. Combination of real-time 3D color Doppler flow rate estimation and pulsed-wave Doppler echocardiography for quantifying stroke volume through the left ventricular outflow tract. J Am Coll Cardiol 2001;37(2):442A.

194. Watanabe J, Jones M, Shiota T, Bauer F, Tsujino H, Kim YJ, Garcia MJ, Qin JX, Sitges M, Travaglini A, Thomas JD. Color M-mode Doppler flow propagation of

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late diastolic velocity caused by left atrial-left ventricular pressure gradient: An animal study. J Am Coll Cardiol 2001;37(2):435A.

195. Watanabe J, Jones M, Shiota T, Tsujino H, Zetts AD, Qin JX, Cardon LA, Sitges M, Bauer F, Kim YJ, Garcia MJ, Thomas JD. Characteristics of left ventricular aneurysm by color M-mode echocardiography: A chronic animal study. J Am Coll Cardiol 2001;37(2):418A.

196. Wang K, Zhou Z, Zhou X, Tarakji K, Qin JX, Sitges M, Shiota T, Topol EJ, Lincoff AM. Protection of left ventricular function with recombinant soluble P-selectin Glycoprotein Ligand-Ig in the canine coronary balloon occlusion model. J Am Coll Cardiol 2001;37(2):369A.

197. Hang X, Greenberg NL, Qin JX, Shiota T, Thomas JD. Compression of real-time 3D volumetric data based on 3D wavelet packet transform. J Am Soc Echocardiogr 2001;14(5):486.

198. Kim YJ, Jones M, Shiota T, Qin JX, Bauer F, Sitges M, Tsujino H, Cardon LA, Zetts AD, Panza JA, Thomas JD. Hemodynamic effects of aortic regurgitation on LV volume, mass and contractility in chronic aortic regurgitation: Animal study with electromagnetic flowmeters and Real-time 3D echocardiography. J Am Soc Echocardiogr 2001;14(5):451.

199. Kwan J, Jones M, Shiota T, Qin JX, Kim YJ, Tsujino H, Zetts AD, Thomas JD. Acute changes of mitral annular geometry after coronary occlusion (LAD and LCX) in sheep model: Real time 3D echo study. J Am Soc Echocardiogr 2001;14(5):485.

200. Qin JX, Shiota T, Jones M, Tsujino H, Sitges M, Kim YJ, Hang X, Zetts AD, Stewart WJ, Thomas JD. Validation of the combination use of real-time 3DE and automatic cardiac output measurement for quantifying mitral regurgitation and stroke volume. J Am Soc Echocardiogr 2001;14(5):449.

201. Qin JX, Shiota T, Tsujino H, Agler DA, Bauer F, Gillinov AM, Cosgrove DM, Stewart WJ, Thomas JD. Does mitral valve repair in patients with mitral valvular prolapse change transmitral inflow velocity and pattern? A clinical 2D and real-time 3D Echocardiographic study. J Am Soc Echocardiogr 2001;14(5):451.

202. Qin JX, Shiota T, Xu Y, Tsujino H, Sitges M, McCarthy PM, Thomas JD. Tricuspid annular motion, a useful index for detecting right ventricular ejection fraction: A Real-time 3-dimensional echocardiographic study. J Am Soc Echocardiogr 2001;14(5):478.

203. Qin JX, Shiota T, Tsujino H, Sitges M, Kim YJ, Kwan J, Hang X, McCarthy PM, Thomas JD. Geometry and function of tricuspid annulus in comparison with mitral

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annulus: A Real-time 3-dimensional echocardiographic study. J Am Soc Echocardiogr 2001;14(5):486.

204. Saracino G, Lamberti C, Sarti A, Corsi C, Qin JX, Shiota T, Thomas JD. Semiautomatic left ventricular volume determination from real-time 3D echocardiography: An in vitro validation study. J Am Soc Echocardiogr 2001;14(5):487.

205. Sitges M, Jones M, Shiota T, Qin JX, Kim YJ, Kwan J, Tsujino H, Bauer F, Cardon LA, Zetts AD, Thomas JD. Effect of left ventricular loading conditions on the non- invasive quantification of the regurgitant orifice area in mitral valve prolapse by the proximal flow convergence method: A simultaneous echocardiographic and hemodynamic study. J Am Soc Echocardiogr 2001;14(5):450.

206. Watanabe J, Jones M, Shiota T, Tsujino H, Bauer F, Garcia MJ, Qin JX, Travaglini A, Kim YJ, Sitges M, Thomas JD. Correlation between color M-mode propagation velocity and diastolic indices: An animal study. J Am Soc Echocardiogr 2001;14(5):493.

207. Yang H, Pu M, Qin JX, Vlassak I, Shiota T, McCarthy PM, Thomas JD, Garcia MJ. Do regional left ventricular wall motion abnormalities predict left ventricular function after infarction exclusion surgery? J Am Soc Echocardiogr 2001;14(5):480.

208. Yamada H, Jones M, Shiota T, Qin JX, Greenberg NL, Kim YJ, Watanabe J, Cardon LA, Abe Y, Tsujino H, Kanda R, Thomas JD. Assessment of nonuniformity of the transmural myocardial velocity profile by angle corrected tissue Doppler imaging: Characterization of normal, transmurally infarcted and nontransmurally infarcted myocardium. Circulation 2001; 104(17):II-628

209. Qin JX, Shiota T, Lever HM, Greenberg NG, Agler DA, Drinko JK, Martin M, Schnauffer MJ, Smedira NG, Tuzcu EM, Lytle B, Thomas JD. Untoward effect of septal reduction interventions on conduction system in patients with obstructive hypertrophic cardiomyopathy. J Am Coll Cardiol 2002; 39(5):132A

210. Qin JX, Shiota T, Kim YJ, Tsujino H, Agler DA, Hang X, Kwan J, McCarthy PM, Thomas JD. Geometry of tricuspid annulus determined by real-time 3D echo in tricuspid regurgitant patients geometry of tricuspid annulus determined by real-time 3D echo in tricuspid regurgitant patients with intact leaflets. J Am Coll Cardiol 2002; 39(5):349A

211. Qin JX, Shiota T, White RD, Cardon LA, Greenberg NL, Stewart WJ, Thomas JD. Validation of Mitral Annular Motion Assessed by Real-time 3-dimensional Echocardiography for Quantification of Left Ventricular Function: a Comparison with Magnetic Resonance Imaging. J Am Coll Cardiol 2002; 39(5):344A

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212. Kim YJ, Jones M, Shiota T, Qin JX, Greenberg NL, Popovic ZB, Kwan J, Sitges M, Bauer F, Yang H, Cardon LA, Sachdev V, Griffin BP, Cosgrove DM, Thomas JD. Evaluation of left ventricular contractile function using noninvasively derived end- systolic elastance in mitral regurgitation: Experimental validation and clinical study. J Am Coll Cardiol 2002; 39(5):372A

213. Kwan J, Shiota T, Gillinov AM, Agler DA, Qin JX, Kim YJ, Thomas JD. Geometric differences of mitral valvular apparatus between ischemic and dilated cardiomyopathy with significant mitral regurgitation: Real-time 3D echocardiography study. J Am Coll Cardiol 2002; 39(5):395A

214. Kwan J, Shiota T, Gillinov AM, Agler DA, Qin JX, McCarthy PM, Thomas JD. Geometric determinants of significant mitral regurgitation in patients with severe ischemic cardiomyopathy. J Am Coll Cardiol 2002; 39(5):430A.

215. Saracino G, Lamberti C, Corsi C, Qin JX, Shiota T, Thomas JD. Fast interactive visualization of human heart in 3D space using real time three-dimensional echocardiographic (RT3DE) dataset on commercially available low cost computer. J Am Coll Cardiol 2002; 39(5):344A

216. Yang H, Jones M, Shiota T, Qin JX, Kim YJ, Daugherty DW, Popovic Z, Greenberg NL, Pu M, Cardon LA, Zetts AD, Thomas JD. Changes of mitral regurgitation severity under altered loading conditions and its relationship to pulmonary venous flow. J Am Coll Cardiol 2002;39(5):384A

217. Watanabe J, Jones M, Shiota T, Tsujino H, Greenberg NL, Popovic ZB, Zetts AD, Qin JX, Cardon LA, Garcia MJ, Thomas JD. Color M-mode estimation of the spatial distribution of the diastolic intraventricular pressure gradient with a left ventricular aneurysm. J Am Coll Cardiol 2002;39(5):366A

218. Yang H, Sun JP, Lever HM, Popovic ZB, Drinko JK, Greenberg NL, Shiota T, Thomas JD, Garcia MJ. Echocardiographic assessment of abnormal regional myocardial strain in patients with hypertropic cardiomyopathy. J Am Soc Echocardiogr 2002;15(5):485.

219. Eto Y, Jones M, Shiota T, Qin JX, Khan GN, Kim YJ, Zetts AD, Sachdev V, Thomas JD. Left ventricular volume measurement using an automated contour tracking method (ACT) in animals with left ventricular aneurysm: comparison with real-time three-dimensional echocardiography. J Am Soc Echocardiogr 2002;15(5):489.

220. Yamada H, Jones M, Shiota T, Qin JX, Kim YJ, Greenberg NL, Abe Y, Tsujino H, Kanda R, Zetts AD, Thomas JD. Effect of an increase in afterload on tissue Doppler derived systolic myocardial velocity gradient. J Am Soc Echocardiogr 2002;15(5):494.

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221. Eto Y, Qin JX, Shiota T, Sitges M, Wang K, Zhou Z, Zhou Z, Hang X, Kim YJ, Lincoff AM, Thomas JD. Anti-p-selectin prevent myocardial ischemia-reperfusion injury: A real-time 3D and 2 D echocardiographic assessment. J Am Soc Echocardiogr 2002; 15(5): 511.

222. Shin JH, Shiota T, Rodriguez LL, Thomas JD. False positive result of exercise stress echocardiography to detect coronary artery disease in patients with normal resting left ventricular wall motion. J Am Soc Echocardiogr 2002;15(5):519.

223. Yamada H, Jones M, Shiota T, Qin JX, Kim YJ, Greenberg NL, Tsujino Y, Abe Y, Kanda Y, Zetts AD, Thomas JD. Assessment of the longitudinal (apex to base) myocardial velocity profile using tissue Doppler imaging in sheep with chronic myocardial infarction. J Am Soc Echocardiogr 2002;15(5):522.

224. Kim YJ, Jones M, Shiota T, Qin JX, Greenberg NL, Popovic ZB, Kwan J, Yamada H, Eto Y, Shin JH, Zett AD, Sachdev V, Thomas JD. Impact of infarct size on the end-systolic pressure-area relation of remote non-infarcted myocardium in chronic myocardial infarction: an animal study. J Am Soc Echocardiogr 2002;15(5):522.

225. Qin JX, Shiota T, Lever HM, Kim YJ, Kwan J, Agler DA, Drinko JK, Tuzcu EM, Thomas JD. Left ventricular remodeling after percutaneous transluminal septal myocardial ablation in patients with hypertrophic obstructive cardiomyopathy, real- time 3D and 2D echo studies. J Am Soc Echocardiogr 2002;15(5):537.

226. Firstenberg MS, Morehead AJ, Garcia MJ, Agler DA, Shiota T, Thomas JD. Improved activating clotting time rather than hemodynamic changes account for decreases in paravalvular regurgitant jets following valve replacement. J Am Soc Echocardiogr 2002;15(5):540.

227. Kim YJ, Shiota T, Qin JX, Greenberg NL, Popovic ZB, Kwan J, Sitges M, Bauer F, Agler DA, Griffin BP, Cosgrove DM, Thomas JD. Evaluation of left ventricular contractile function using noninvasively derived single-beat end-systolic elastance in patients with mitral regurgitation. J Am Soc Echocardiogr 2002;15(5):540.

228. Donal E, Kim YJ, Popovic ZB, Shiota T, Thomas JD. Impact of atrio-ventricular compliance and valve structure on exercise capacity. Echocardiographic study about 35 women with mitral stenosis. J Am Soc Echocardiogr 2002; 15(5):540.

229. Kwan J, Shiota T, Shin JH, Kim YJ, Agler DA, Thomas JD. Localization of two separated heads of a papillary muscle using real-time 3D echocardiography. J Am Soc Echocardiogr 2002; 15(5):544.

230. Kwan J, Shiota T, Qin JX, Agler DA, Thomas JD. Geometric changes of mitral annlus during systole assessed by real-time 3D echocardiography: flattened and

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elongated in the antero-posterior direction in proportion to global LV systolic function. J Am Soc Echocardiogr 2002; 15(5):544.

231. Khan GN, Jones M, Shiota T, Qin JX, Kim YJ, Zetts AD, Thomas JD. Three- dimensional echocardiographic quantification of aneurysmal left ventricular volumes in response to altered preload and afterload states in an animal model. J Am Soc Echocardiogr 2002; 15(5):545.

232. Saracino G, Qin JX, Shiota T, Thomas JD, Corsi C, Lamberti C. Fast and interactive volume rendering from real-time three-dimensional echocardiography. J Am Soc Echocardiogr 2002; 15(5):545.

233. Qin JX, Shiota T, Shin JH, Agler DA, Borowski AG, Grimm RA, Wilkoff B, Thomas JD. Tracking pacemaker wire and lead in patients with permanent right ventricular pacing by live 3D echo: Comparison with 2D Echo. J Am Soc Echocariogr 2003;16:546.

234. Qin JM, Shiota T, Shin JH, Agler DA, Drinko JK, Nash PJ, Smedira NG, Asher CR, Lever HM, Thomas JD. Quantification of left ventricular outflow tract by live 3D echo in patients with hypertrophic cardiomyopathy. J Am Soc Echocariogr 2003;16:546.

235. Qin JX, Shiota T, Agler DA, Kwan J, Shin JH, Saracino G, McCarthy PM, Thomas JD. Deformation of mitral annulus in patients with ischemic mitral regurgitation: A real-time 3D echo study. J Am Soc Echocardiogr 2003;16:546.

236. Shin JH, Shiota T, Qin JX, Agler DA, Greenberg NL, Oryszak S, Nash PJ, Eto Y, Thomas JD. Validation of live three-dimensional echocardiography for quantification of left ventricular volume: Comparison with volumetric real-time three-dimensional echocardiography. J Am Soc Echocardiogr 2003;16:551.

237. Shin JH, Shiota T, Qin JX, Agler DA, Greenberg NL, Oryszak S, Martin M, Nash PJ, Eto Y, Thomas JD. Reproducibility o live three-dimensional echocardiography in measurement of left ventricular volumes. J Am Soc Echocardiogr 2003;16:551.

238. Shin JH, Shiota T, Qin JX, Eto Y, Thamilarasan M, Thomas JD, Rodriguez LL. Role of ultra sensitive c-reactive protein in patients with regional wall motion abnormality during exercise echocardiography. J Am Soc Echocardiogr 2003;16:552.

239. Agler DA, Qin JX, Shiota T, Shin JH, Nash PJ, Morehead AJ, Greenberg NL, Stewart WJ, Cosgrove DM, Thomas JD. Initial experience of epicardial live 3D echo for determining mitral valvular pathology: Operative validation. J Am Soc Echocardiogr 2003;16:501.

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240. Agler DA, Qin JX, Shiota T, Shin JH, Kassimatis C, Nash PJ, Oryszak S, Pettersson G, Griffin B, Grimm R, Thomas JD. Aortic abnormalities determined by live 3D echo: Comparison with 2D echocardiographic study. J Am Soc Echocardiogr 2003;16:501.

241. Gao ZH, Shiota T, Xu X, Qin JX, Carneiro M, Thomas JD. Heterogeneity of regional myocardial isovolumic systolic and diastolic time in coronary artery disease without left ventricular wall motion abnormality. J Am Soc Echocariogr 2003;16(5):518.

242. Gao ZH, Shiota T, Qin JX, Xu X, Thomas JD. Mechanism of aortic root dilation in patients with congenital bicuspid aortic valve. J Am Soc Echocariogr 2003;16(5):519.

243. Notomi Y, Popovic ZB, Yamada H, Desserrano D, Qin JM, Greenberg NL, Thomas JD, Shiota T. Temporal relation between left ventricular torsional, longitudinal and radial recoil in early diastole assessed by tissue Doppler echocardiography. J Am Soc Echocardiogr 2003;16:539.

244. Notomi Y, Qin JX, Popovic ZB, Greenberg NL, Thomas JD, Shiota T. Assessment of left ventricular twisting during exercise using tissue Doppler echocardiography. J Am Soc Echocardiogr 2003;16:539.

245. Eto Y, Shiota T, Qin JX, Shin JH, Bauer F, Agler DA, Saracino G, Greenberg NL, Thomas JD. Assessment of left atrial conduit volume in patients with hypertrophic cardiomyopathy using real-time threee-dimensional echocardiography. J Am Soc Echocardiogr 2003;16:517.

246. Shin JH, Shiota T, Qin JX, Eto Y, Thomas JD, Rodriguez LL. Impact of blood pressure on false –positive results during exercise echocardiography. Is there a gender difference? J Am Coll Cardiol 2003;41:470A

247. Shin JH, Shiota T. Qin JX, Kim YJ, Popovic ZB, Gillinov AM, Cosgrove DM, Thomas JD. Forward stroke volume preserved during left ventricular remodeling after mitral valve repair. J Am Coll Cardiol 2003;41:515A.

248. Saracino G, Shiota T, Qin JX, Thomas JD. A new computerized method to trace mitra anulus in three-dimentional space from three-dimentional echocariographic (RT3DE) image: An in vitro validation study. J Am Coll Cardiol 2003;41:520A.

249. Notomi Y, Yamada H, Popovic ZB, Qin JX, Greenberg NL, Abe Y, Kanada R, Thomas JD, Shiota T. “Wringing” motion of normal left ventricle quantifies with tissue Dopppler echocardiography. J Am Coll Cardiol 2003;41:441A

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250. Saracino G, Shiota T, Qin JX, Greeenberg NL, Thomas JD. Determination of mitral annular 3D geometry from real-time 3D echocardiography: An in-vitro validation and clinical study. J Am Coll Cardiol 2003;41:430A

251. Shin JH, Jones M, Qin JX, Agler DA, Greenberg N, Oryszak S, Saracino G, Eto Y, Shiota T. Automated computer analysis of left ventricular functions using real-time three-dimensional echocardiography: A chronic animal study. Circulation 2003;102:338

252. Eto Y, Yamada H, Shiota T, Shin JH, Qin JX, Agler D, Saracino G, Tsujino H, Thomas JD. Assessment of longitudinal and radial mitral annular movement in left ventricular dysfunction using automated mitral annular tracking. Circulation 2003;102:440

253. Saracino G, Greenberg N, Qin JX, Corsi C, Shin JH, Yoko E, Shiota T. A novel semi-automatic 3D echo method for the assessment of mitral annular geometry in mitral valve prolapse, ischemic mitral regurgitation and normals. Circulation 2003;102:554

254. Qin JX, Shiota T, Shin JH, Agler DA, Drinko JK, Nash PJ, Smedira NG, Asher CR, Lever HM. Intraoperative real-time 3D echocardiography, a new approach to evaluate myectomy in patients with hypertrophic cardiomyopathy. Circulation 2003;102:595

255. Notomi Y, Popovic ZB, Desserrano D, Shiota T. Description of left ventricular torsional deformation by tissue Doppler echocardiography. Circulation 2003;102:661.

256. Notomi Y, Grimm R, Shiota T, Agler D, Martin M, Desserrano D, Greenberg N, Thomas JT. Deterioration of apical rotation in dilated cardiomyopathy with left bundle branch block. Circulation 2003;102:662.

257. Notomi Y, Shiota T, Popovic ZB, Yamada H, Martin-Miklovic MG, Deserranno DG, Wallick DW, Greenberg NL, Garcia MJ, Thomas JD. Assessment of ventricular untwisting recoil velocity by Doppler tissue echocardiography: An index of relaxation time constant. J Am Coll Cardiol 2004;43(5)189A.

258. Qin JX, Shiota T, Shin JH, Saracino G, Fukamachi K, Banbury MK, Young JB, McCarthy PM, Thomas JD. Left ventricular modification by Myocor Myosplint in patients with dilated cardiomyopathy. A three –month follow-up study with real- time 3-D and 2-D echo. J Am Coll Cardiol 2004;43(5)344A.

259. Notomi Y, Setser RM, Shiota T, Martin-Miklovic MG, Kasper JM, Popovic ZB, Yamada H, Deserranno DG, Greenberg NL, Garcia MJ, White RD, Thomas, JD. Assessment of left ventricular torsional deformation by Doppler tissue imaging: A

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validation study using tagged magnetic resonance imaging. J Am Coll Cardiol 2004;43 (5)372A.

260. Shiota, M, Qin JX, McCarthy PM, Gillinov AM, Shin JH, Williams T, Cosgrove DM, Thomas JD, Shiota T. Comparison between successful and unsuccessful mitral valve repair of ischemic mitral regurgitation: An echocardiographic follow-up study. J Am Coll Cardiol 2004;43(5)433A.

261. Kongsaerepong V, Shiota M, Song JM, Qin JX, McCarthy PM, Gillinov AM, Shin JH, Williams T, Cosgrove DM, Thomas, JD, Shiota T. Mitral annular diameter, and independent predictor for successful mitral valve repair in patients with ischemic MR: An echocardiographic study. J Am Soc Echocardiogr 2004;17:507.

262. Daimon M, Saracino G, Song JM, Kongsaerepong V, Fukuda S, Qin JX, Gillinov AM, Shiota T. Dynamic change in mitral annular Geometry during a cardiac cycle in patients with ischemic and dilated cardiomyopathy: A novel computerized 3D echo method. J Am Soc Echocardiogr 2004;17:519.

263. Qin JX, Shiota T, Shin JH, Agler DA, Saracino G, Gillinov AM, McCarthy PM, Thomas JD. Immediate changes of mitral apparatus and hemodynamic after annuloplasty repair in patient with ischemic mitral regurgitation: 2D and 3D echo studies. J Am Soc Echocardiogr 2004;17:520.

264. Agler DA, Qin JX, Shiota T, Troughton R, Sallach JA, Kassimatis K, Pettersson G, Griffin B, Grimm R, Thomas JD. Left ventricular mass and volume decrease following aortic valve replacement: A real-time three dimensional echocardiography study. J Am Soc Echocardiogr 2004;17:520.

265. Notomi Y, Gowdagere S, Shiota T, Greenberg NL, Younoszai A, Thomas JD. Growing ventricular untwisting in childhood. J Am Soc Echocardiogr 2004;17:523.

266. Popovic ZB, Martin M, Fukamachi K, Inoue M, Schenk S, Shiota T, Thomas JD. Impact of thoracotomy with pericardiotomy on mitral regurgitation and valve geometry in the presence of dilated cardiomyopathy: A real time 3- dimensional and 2-dimensional color Doppler echocardiographic study. J Am Soc Echocardiogr 2004;17:523.

267. Saracino G, Shiota T, Daimon M, Thomas JD. Dynamic change in angulation between aortic and mitral annular plane: A clinical real-time 3D echocardiographic study with a custom made novel computer technique. J Am Soc Echocardiogr 2004;17:520.

268. Shin JH, Shiota T, Qin JX, Agler DA, Saracino G, Greenberg NL, Oryszak S, Nash PJ, Eto Y, Thomas JD. Validation of live three-dimensional echocardiography for

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269. Notomi Y, Shiota T, Martin-Miklovic MG, Popovic ZB, Yamada H, Oryszak SJ, Wallick DW, Grimm RA. Effect of alteration of left ventricular activation sequence on the left ventricular torsional deformation in anesthetized closed-chest dogs. Circulation 2004;110(17)III-140.

270. Kongsaerepong V, Song JM, Shiota M, Qin JX, McCarthy PM, Gillinov AM, Shin JH, Williams T, Cosgrove DM, Thomas JD, Shiota T. Mitral annular diameter, an independent predictor for successful mitral valve repair in patients with ischemic MR: An echocardiographic study. Circulation 2004;110(17)III-2192.

271. Daimon M, Shiota T, Liddicoat J, Hayase M, Ruel M, Cohn W, Blacker S, Gillinov AM. Percutaneous mitral valve repair for chronic ischemic mitral regurgitation: Feasiblity study in ovine model. Circulation 2004;110(17)III-2305.

272. Notomi Y, Shiota T, Martin-Miklovic MG, Oryszak SJ, Deserranno D, Greenberg NL. Torsion-volume loop analysis for assessment of left ventricular active relaxation. Circulation 2004;110(17)III-2234.

273. Daimon M, Saracino, Song JM, Kongsaerepong V, Fukuda S, Qin JX, Gillinov AM, Shiota T. Dynamic change in mitral annular geometry during a cardiac cycle in patients with ischemic and dilated cardiomyopathy: A novel computerized 3D echo method. Circulation 2004;110(17)III-3037.

274. Fukuda S, Gillinov AM, Song JM, Daimon M, Kongsaerepong V, Kihara T, Greenberg NL, Thomas JD, Shiota T. The effect of tricuspid valve surgery on right ventricular function n patients with functional tricuspid regurgitation. J Am Coll Cardiol 2005;45(3):873A.

275. Fukuda S, Song JM, Gillinov AM, Daimon M, Kongsaerepong V, Greenberg NL, Thomas JD, Shiota T. Tricuspid valve tethering predicts residual regurgitation after tricuspid annuloplasty. J Am Coll Cardiol 2005;45(3):1159A.

276. Song JM, Qin JX, Kongsaerepong V, Daimon M, Fukuda S, Agler DA, Drinko JK, Martin M, Lever HM, Shiota T. Asymmetry of systolic anterior motion of mitral valve in patients with hypertrophic obstructive cardiomyopathy: A real-time three- dimensional echocardiographic study. J Am Coll Cardiol 2005;45(3):1162A.

277. Daimon M, Shiota T, Liddicoat J, Hayase M, Ruel M, Cohn W, Blacker SJ, Gillinov AM. Percutaneous mitral valve repair for chronic ischemic mitral regurgitation: Real-time 3D echocardiographic study. J Am Coll Cardiol 2005;45(3):1001A.

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278. Notomi Y, Popovic ZB, Wallick DW, Martin-Miklovic MG, Oryszak SJ, Shiota T, Agler DA, Grimm RA, Greenberg NL, Thomas JD. Mechanical activation sequence mapping by regional strain analysis derived from ultrasound 2D speckle tracking imaging. Circulation 2005;112(17) 1716.

279. Daimon M, Saracino G, Fukuda S, Koyama Y, Song JM, Agler DA, Gillinov AM, Thomas JD, Shiota T. Dynamic change in mitral annular geometry during the cardiac cycle in patients with ischemic mitral regurgitation: A novel computerized 3D echo method. Circulation 2005;112(17) 1976.

280. Fukuda S, Lever HM, Kapadia SR, Tuzcu EM, Murphy R, Tran H, Song JM, Shin MS, Greenberg NL, Smedira NG, Lytle B, Thomas JD, Shiota T. Determinants of success of reduction of mitral regurgitation after septal reduction therapy in hypertrophic obstruction cardiomyopathy: A real-time three-dimensional echocardiography study. Circulation 2005;112(17) 2376.

281. Fukuda S, Gillinov AM, McCarthy PM, Song JM, Kihara T, Daimon M, Tran H, Thomas JD, Shiota T. Mechanism of recurrent or residual functional tricuspid regurgitation mid-term after tricuspid annuloplasty. Circulation 2005;112(17) 2378.

282. Daimon M, Gillinov AM, Liddicoat J, Saracino G, Fukuda S, Koyama Y, Hayase M, Ruel M, Ellis SG, Cohn W, Thomas JD, Shiota T. Dynamic changes in mitral annular area and motion during percutaneous transvenous mitral annuloplasty in ischemic mitral regurgitation: A real-time 3D echocardiographic study. Circulation 2005;112(17) 2947.

283. Fukuda S, Saracino G, Matsumura Y, Tran H, Daimon M, Greenberg NL, Hozumi T, Yoshikawa J, Thomas JD, Shiota T. Three-Dimensional geometry and motion of tricuspid annulus in healthy subjects and patients with functional tricuspid regurgitation. Circulation 2005;112(17) 3322.

284. Daimon M, Shiota T, Fukuda S, Blackstone E, McCarthy PM, Gillinov AM. Early results of mitral valve repair with Carpentier-McCarthy-Adams IMR ETIogix annuloplasty ring in ischemic mitral regurgitation. Circulation 2005;112(17) 3324.

285. Daimon M, Saracino G, Koyama Y, Kwan J, Song JM, Fukuda S, Agler DA, Gillinov AM, Thomas JD, Shiota T. Local dysfunction and asymmetrical deformation of mitral annular geometry in ischemic mitral regurgitation: A novel computerized 3D echocardiographic method. Circulation 2005;112(17) 3346.

286. Notomi Y, Lysyansky P, Setser R, Popovic ZB, Martin-Miklovic MG, Weaver JA, Oryszak SJ, Shiota T, Greenberg NL, White RD, Thomas JD. Measurement of ventricular torsion by 2D ultrasound speckle tracking imaging. J Am Soc Echocardiogr 2005;18(5)500.

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287. Fukuda S, Saracino G, Matsumura Y, Daimon M, Thomas JD, Hozumi T, Yoshikawa J, Shiota T. Three-dimensional geometry of tricuspid valve annulus in patients with functional tricuspid regurgitation: A novel computerized 3D echo method. J Am Soc Echocardiogr 2005;18(5)526.

288. Notomi Y, Popovic ZB, Wallick DW, Martin-Miklovic MG, Oryszak SJ, Deserranno D, Shiota T, Garcia MJ, Greenberg NL, Thomas, JD. Pressure-volume, pressure torsion, torsion-volume loop analysis for assessing mechanical active relaxation and suction. J Am Soc Echocardiogr 2005;18(5)531.

289. Kihara T, Hoercher KJ, Alster JM, Fukuda S, Smedira NG, Shiota T. Effect of Dor Procedure on left ventricular diastolic function as assessed with echocardiography. J Am Soc Echocardiogr 2005;18(5)542.

290. Daimon M, Shiota T, Liddicoat J, Hayase M, Ruel M, Cohn W, Blaker SJ, Saracino G, Thomas JD, Gillinov AM. Percutaneous mitral valve repair for chronic ischemic mitral regurgitation: A novel real-time 3D echocardiographic study. J Am Soc Echocardiogr 2005;18(5)544.

291. Fukuda, S, Grimm RA, Daimon M, Song JM, Kihara T, Agler DA, Wilkoff BL, Natale A, Thomas JD, Shiota T. Ventricular Asynchrony effects on phasic pattern of functional mitral regurgitation. J Am Soc Echocardiogr 2005;18(5)544.

292. Kihara T, Hoercher KJ, Alster JM, Fukuda S, Smedira NG, Shiota T. Effect of Dor Procedure on mild mitral valve regurgitation as assessed with echocardiography. J Am Soc Echocardiogr 2005;18(5)546.

293. Song JM, Fukuda S, Kihara T, Shin MS, Qin JX, Agler DA, Thomas JD, Shiota T. Dynamic change in mitral valve tenting volumes in patients with functional mitral regurgitation: A real-time three-dimensional echocardiographic study. J Am Soc Echocardiogr 2005;18(5)548.

294. Shin MS, Fukuda S, Song JM, Daimon M, Tran H, Thomas JD, Shiota T. Relationship between left atrial and left ventricular function in hypertrophic cardiomyopathy: A real time 3D echocardiographic study. J Am Coll Cardiol 2006;47(4)50A.

295. Fukuda S, Tran H, Lever HM, Song JM, Shin MS, Greenberg NL, Thomas JD, Shiota T. Assessment of the Severity of outflow obstruction in patients with hypertrophic cardiomyopathy: A real-time dimensional echocardiographic study. J Am Coll Cardiol 2006;47(4)146A.

296. Daimon M, Fukuda S, Adams D, McCarthy PM, Gillinov AM, Carpentier A, Filsoufi F, Abascal VM, Rigolin VH, Huskin A, Langenfeld M, Shiota T. Mitral valve repair with a novel etiology-specific annuloplasty ring for ischemic mitral

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regurgitation: Early echocardiographic results from a multi-center study. J Am Coll Cardiol 2006;47(4)146A.

297. Fukuda S, Gillinov AM, McCarthy PM, Daimon M, Song JM, Shin MS, Thomas, JD, Shiota T. Initial experience of new three-dimensional annuloplasty ring for functional tricuspid regurgitation. J Am Coll Cardiol 2006;47(4)273A.

298. Shiota M, Gillinov AM, Fukuda S, Greenberg NL, Thomas JD, Shiota T. Mechanism of recurrent mitral regurgitation after annuloplasty for ischemic mitral regurgitation: An Echocardiographic study. J Am Soc Echocardiogr 2006;19(5)657.

299. Daimon M, Saracino G, Fukuda S, Agler DA, Gillinov AM, Thomas JD, Shiota T. Mitral annular dilatation in patients with functional mitral regurgitation: A novel computerized 3D echo method. J Am Soc Echocardiogr 2006;19(5)637.

300. Fukuda S, Gillinov AM, Song JM, Daimon M, Kongsaerepong V, Thomas JD, Shiota T. Echocardiographic insights into ventricular mechanisms of functional tricuspid regurgitation. J Am Soc Echocardiogr 2006;19(5)586.

301. Fukuda S, Gillinov AM, Liddicoat JR, Saracino G, Hayase M, Ruel M, Cohn WE, Blacker SJ, Shiota T. Follow up of percutaneous mitral valve repair by real-time three-dimensional echocardiographic assessment in an ovine model. J Am Soc Echocardiogr 2006;19(5)651.

302. Fukuda S, Gillinov AM, Liddicoat JR, Saracino G, Hayase M, Ruel M, Cohn WE, Blacker SJ, Shiota T. Changes in three-dimensional of mitral annulus after percutaneous valve repair in an ovine model of chronic ischemic mitral regurgitation. J Am Soc Echocardiogr 2006;19(5)657.

303. Fukuda S, Gillinov AM, Liddicoat JR, Isreal B, Saracino G, Hayase M, Ruel M, Cohn WE, Schneider CW, Shiota T. Mid-term efficacy of percutaneous mitral valve repair: A real-time three-dimensional echocardiographic study in an ovine model. Circulation 2006; 114(18)2711.

304. Fukuda S, Lever HM, Stewart JW, Tran H, Song JM, Shin MS, Greenberg NL, Wada N, Matsumura Y, Toyono M, Smedira NG, Thomas JD, Shiota T. Diagnostic value of left ventricular outflow area in patients with hypertrophic cardiomyopathy: A real-time three dimensional echocardiographic study. J Am Coll Cardiol 2007;49(9)127A.

305. Wada N, Fukuda S, Toyono M, Matsumura Y, Thomas JD, Watanabe N, Yoshida K, Shiota T. Geometric deformity of the mitral annulus in patients with hypertrophic obstructive cardiomyopathy: Real-time three-dimensional echocardiographic study. J Am Coll Cardiol 2007;49(9)163A.

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306. Toyono M, Fukuda S, Wada N, Matsumura Y, Pettersson G, Thomas JD, Shiota T. Clinical significance of mitral valve prolapse in adult patients with atrial septal defect. J Am Coll Cardiol 2007;49(9)266A.

307. Matsumura Y, Fukuda S, Tran H, Greenberg NL, Agler DA, Wada N Toyono M, Thomas JD, Shiota T. Geometry of the proximal isovelocity surface area of mitral regurgitation by three-dimensional color Doppler echocardiography: Difference between functional mitral regurgitation and mitral valve prolapse. J Am Coll Cardiol 2007; 49(9) 301A.

308. Shiota M, Gillinov AM, Fukuda S, Greenberg NL, Thomas JD, Shiota T. Recurrent mitral regurgitation late after annuloplasty for ischemic mitral regurgitation: An echocardiographic study. J Am Coll Cardiol 2007; 49(9)307A.

309. Wada N, Matsumura Y, Toyono M, Fukuda S, Hung T, Greenberg NL, Tsukiji M, Wantanbe N, Yoshida K, Thomas JD, Shiota T. Geometric deformity of the mitral annulus in patients with hypertrophic obstructive cardiomyopathy: Real-time three- dimensional echocardiographic study J Am Soc Echocardiogr 2007;20(5)P1-07.

310. Matsumura Y, Fukuda S, Saracino G, Tran H, Greenberg NL, Agler DA, Wada N, Toyono M, Thomas JD, Shiota T. Dynamic variation in functional mitral regurgitation: A real-time three-dimensional color Doppler echocardiography study. J Am Soc Echocardiogr 2007;20(5)P1-46.

311. Wada N, Gillinov MA, Fukuda S, Toyono M, Matsumura Y, Thomas JD, Shiota T. Echocardiographic parameters of persistent systolic anterior motion (SAM) after optimal anesthetic management in the operating room in patients with mitral valve repair. J Am Soc Echocardiogr 2007;20(5)P1-71.

312. Toyono M, Wada N, Matsumura Y, Fukuda S, Pettersson GB, Thomas JD, Shiota T. Functional status and ventricular performance in adult patients with atrial septal defect. J Am Soc Echocardiogr 2007;20(5)P2-70.

313. Matsumura Y, Saracino G, Fukuda S, Tran H, Greenberg NL, Wada N, Toyono M, Thomas JD, Shiota T. Calculation of the proximal isovelocity surface area in functional mitral regurgitation by using hemi-ellipsoidal assumption: A real time three-dimensional color Doppler echocardiographic study. J Am Soc Echocardiogr 2007;20(5)P288.

314. Matsumura Y, Fukuda S, Tran H, Greenberg NL, Wada N, Toyono M, Thomas JD, Shiota T. Relation between mitral valve geometry and the proximal isovelocity surface area of mitral regurgitation in patients with functional mitral regurgitation: A real-time three-dimensional color Doppler echocardiographic study. Am Soc Echocardiogr 2007;20(5)P94.

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315. Matsumura Y, Gillinov AM, Toyono M, Wada N, Yamano T, Thomas JD, Shiota T. Left ventricular shape predicts the recovery of left ventricular function after isolated aortic valve replacement for aortic valve stenosis. Circulation 2007;116(16)2064.

316. Yamano T, Gillinov AM, Wada N, Matsumura Y, Toyono M, Thomas JD, Shiota T. Preoperative regurgitant volume can predict “unexpected” left ventricular dysfunction after mitral valve repair for chronic mitral regurgitation. Circulation 2007;116(16)2263.

317. Matsumura Y, Saracino G, Sugioka K, Tran H, Greenberg NL, Wada N, Toyono M, Fukuda S, Hozumi T, Thomas JD, Yoshiyama M, Yoshikawa J, Shiota T. Underestimation of the proximal isovelocity surface area by conventional flow convergence method in functional mitral regurgitation: Comparison between hemispheric and 3D hemi-ellipsoidal assumption. Circulation 2007;116(16)3180.

318. Toyono M, Krasuki RA, Pettersson GB, Matsumura Y, Yamano T, Thomas JD, Shiota T. Rate of functional tricuspid regurgitation in adults after closure of atrial septal defects without anly tricuspid valve procedures. J Am Coll Cardiol 2008;51(10)95A.

319. Matsumura Y, Gillinov AM, Toyono M, Yamano T, Wada N, Thomas JD, Shiota T. Mitral valve tenting predicts persistent functional mitral regurgitation after aortic valve replacement in patients with aortic valve stenosis. J Am Coll Cardiol 2008;51(10)275A.

320. Yamano T, Gillinov AM, Takasaki K, Matsumura Y, Toyono M, Thomas JD, Shiota T. Clinical significance of pulmonary hypertension for prediction of postoperative left ventricular dysfunction after mitral valve repair in patients with mitral regurgitation. J Am Soc Echocardiogr 2008;21(5)P554.

321. Matsumura Y, Toyono M, Sugioka K, Tran H, Greenberg NL, Yamano T, Fukuda S, Hozumi T, Thomas JD, Shiota T. Relation between the jet type and mitral valve geometry in functional mitral regurgitation: A real-time three dimensional color Doppler echocardiographic study. J Am Soc Echocardiogr 2008;21(5)556.

322. Toyono M, Fukuda S, Gillinov AM, Pettersson GB, Matsumura Y, Yamano T, Takasaki K, Thomas JD, Shiota T. Different determinants of residual tricuspid regurgitation after bicuspid annuloplasty: Comparison of atrial septal defect and mitral valve disease. J Am Echocardiogr 2008;21(5)557.

323. Matsumura Y, Toyono M, Greenberg NL, Yamano T, Takasaki K, Thomas JD, Shiota T. Predictors for mitral annular geometric abnormalities: A real-time three- dimensional transesophageal echocardiographic study. J Am Soc Echocardiogr 2008;21(5)560.

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324. Matsumura Y, Gillinov AM, Toyono M, Yamano T, Wada N, Thomas JD, Shiota T. Early and mid-term echocardiographic follow-up of left ventricular function after isolated aortic valve replacement for aortic valve stenosis. J Am Soc Echocardiogr 2008;21(5)560.

325. Takasaki K, Yamano T, Gillinov AM, Matsumura Y, Toyono M, Thomas JD, Shiota T. Detection of left ventricular dysfunction with Tei index in normal ejection fraction patients with mitral regurgitation before mitral valve surgery. J Am Soc Echocardiogr 2008;21(5)560

326. Toyono M, Navia JL, Matsumura Y, Yamano T, Takasaki K, Thomas, JD, Shiota T. Echocardiographic follow-up of tricuspid valve repair with a triple leaflet edge-to- edge technique. J Am Soc Echocardiogr 2008;21(5)565.

327. Toyono M, Matsumura Y, Yamano T, Takasaki K, Greenberg NL, Thomas JD, ShiotaT. Comparison of right ventricular size and contractility begtween real-time 3- dimensional echocardiographic and 2-dimensional echocardiography: Analysis in patients with and without right ventricular overload. J Am Soc Ecocardiogr 2008;21(5)569.

328. Toyono M, Krasuki RA, Matsumura Y, Yamano T, Takasaki K, Thomas JD, Shiota T. Does device closure of secundum atrial septal defects affect left atrial function? J Am Soc Echocardiogr 2008;21(5)604.

329. Toyono M, Matsumura Y, Takasaki K, Saraiva RM, Greenberg NL, Agler DA, Shiota T. Real-time 3-dimensional echocardiography is an indispensable tool for assessing right ventricular function in patients with right ventricular pressure overload. Circulation 2008;118(18)720.

330. Yamano T, Gillinov AM, Taskasaki K, Saraiva RM, Matsumura Y, Toyono M, Shiota T. Is revascularization alone truly sufficient in patients with mild mitral regurgitation?: Echocardiographic follow-up of mild ischemic regurgitation after isolated coronary artery bypass grafting. Circulation 2008;118(18)2289.

331. Yamano T, Gillinov AM, Wada N, Matsumura Y, Toyono M, Shiota T. Doppler- derived mitral regurgitation volume as a predictor of postoperative left ventricular dysfunction after mitral valve repair in patients with preoperative normal left ventricular function. Circulation 2008;118(18)2292.

332. Sack S, Kahlert P, Bilodeau L, Pierard L, Lancellotti P, Legrand V, Bartunek J, Vanderheyden M, Hoffman R, Schauerte P, Shiota T, Marks D, Ellis S, Erbel R. Initial human experiences with a non-stented coronary sinus device for the treatment of functional mitral regurgitation in heart failure patients. Circulation 2008;118(18)3052.

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333. Matsumura Y, Gillinov AM, Toyono M, Yamano T, Taskasaki K, Saraiva RM, Shiota T. Echocardiographic predictor for persistent functional/ischemic mitral regurgitation after aortic valve replacement in patients with arotic valve stenosis. Circulation 2008;118(18)4288.

334. Taskasaki K, Yamano T, Gillinov AM, Matsumura Y, Toyono M, Saraiva RM, Shiota T. Preoperative detection of left ventricular dysfunction by doppler time analysis including Tei index in normal ejection fraction patients with mitral regurgitation. Circulation 2008;118(18)4289.

335. Matsumura Y, Toyono M, Greenberg NL, Yamano T, Takasaki K, Saraiva RM, Shiota T. Geometric changes of mitral annulus assessed by real-time 3-dimensional transesophageal echocardiography. Circulation 2008;118(18)5794.

336. Saraiva RM, Yamano T, Matsumura Y, Takasaki K, Toyono M, Agler D, Greenberg N, Thomas JD, Shiota T. Left atrial dysfunction exists in chronic mitral regurgitation and contributes to pulmonary hypertension. J Am Soc Echocardiogr 2009;(22)584.

337. Fukuoka Y, Shimada Y, Kuwahara E, Gurudevan S, Tolstrup K, Siegel RJ, Shiota T. Left atrial size and function are associated to secondary pulmonary hypertension in coronary artery disease. J Am Soc Ecocardiogr 2010;(23)B42.

338. Shimada YJ, Shiota T. Accuracy of right ventricular volumes and function determined by 3-dimensional echocardiography in meta-analysis study. J Am Coll Cardiol 2010;55:A76. E718.

339. Shimada YJ, Shiota T: Underestimation of left atrial volume by 3-dimensional echo- cardiography validated by magnetic resonance imaging: A metal analysis and investigation of the source of bias. Circulation 2010;122: A18481.

340. Thompson KA, Shiota T, Tolstrup K, Gurudevan S, Siegel RJ. The utility of three- dimentional transesophageal echocardiography in the diagnosis of valvular perforations. Circulation 2010;122: A14621.

341. Kuwahara E, Izumo M, Fukuoka Y, Shiota T: Association between jet direction and mitral leaflet tethering in ischemic mitral regurgitation. An echocardiographic study. Circulation 2010;122 A19809.

342. Kuwahara E, Izumo M. Fukuoka Y, Gurudevan S, Tolstrup K, Siegel RJ, Shiota T. Relationship between jet direction and mitral valve tethering in patients with ischemic miitral regurgitation and real-time three dimensional transesophageal echocardiography study. Circulation 2010;122: A19873.

343. Izumo M, Suzuki K, Kikuchi H, Ko S, Eguchi Y, Azumo N, Akashi YJ, Omiya K,

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Miyake F, Shiota T: Mechanism of false positive exercise electrocardiographic testing: an investigation by advanced echocardiography. Circulation 2010;122: A189991.

344. Izumo M, Shiota M, Saitoh T, Kuwahara E, Fukuoka Y, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Utility of three-dimensional transesophageal echocardiography in the diagnosis of valvular perforations. Am J Cardiol. 2011;107(1):100-2.

345 Shimada YJ, Shiota T. A meta-analysis and investigation for the source of bias of left ventricular volumes and function by three-dimensional echocardiography in comparison with magnetic resonance imaging. Am J Cardiol. 2011;107(1):126-38.

346. Shiota M, Gillinov AM, Takasaki K, Fukuda S, Shiota T. Recurrent mitral regurgitation late after annuloplasty for ischemic mitral regurgitation. Echocardiography. 2011;28(2):161-6.

347. Tolstrup K, Shiota T, Gurudevan S, Luthringer D, Luo H, Siegel RJ. Left atrial myxomas: correlation of two-dimensional and live three-dimensional transesophageal echocardiography with the clinical and pathologic findings. J Am Soc Echocardiogr. 2011;24(6):618-24.

348. Thompson KA, Shiota T, Tolstrup K, Gurudevan SV, Siegel RJ. Utility of combined two-dimensional and three-dimensional transesophageal imaging for catheter-based mitral valve clip repair of mitral regurgitation. J Am Soc Echocardiogr. 2011;24(6):611-7.

349. Izumo M, Nalawadi S, Shiota M, Das J, Dohad S, Kuwahara E, Fukuoka Y, Siegel RJ, Shiota T. Mechanisms of acute mitral regurgitation in patients with takotsubo cardiomyopathy: an echocardiographic study. Circ Cardiovasc Imaging. 2011;4(4):392-8.

350. Tornic J, Jarrett C, Shiota T, Gillinov AM, Mihaljevic T. Severe mitral regurgitation in an adult patient with cor triatriatum. J Heart Valve Dis. 2011;20(2):234-6.

351. Fukuda S, Watanabe H, Shimada K, Aikawa M, Kono Y, Jissho S, Taguchi H, Umemura J, Yoshiyama M, Shiota T, Sumiyoshi T, Yoshikawa J. Left atrial thrombus and prognosis after anticoagulation therapy in patients with atrial fibrillation. J Cardiol. 2011;58(3):266-77.

352. Kulkarni M, Conte AH, Huang A, Lubin L, Shiota T, Kar S. Coronary artery disease, acute myocardial infarction, and a newly developing ventricular septal defect: surgical repair or percutaneous closure? J Cardiothorac Vasc Anesth. 2011;25(6):1213-6.

353. Kar S, Buch MH, Hussaini A, Wertman BM, Makkar RR, Shirazi S, Gurudevan SV,

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Shiota T, Tolstrup K, Siegel R. The safety and efficacy of percutaneous left atrial appendage closure for stroke prevention in atrial fibrillation patients: the experience of a large volume single center in the protect AF study. J Am Coll Cardiol 2011; 57: E1995.

354. Kuwahara E, Shiota T, Otsuji Y, Ueno T, Kono M, Kubota K, Ueya N, Yuasa T, Takasaki K, Hamasaki S, Kisanuki A, Sakata R, Tei C. Altered jet direction of ischemic mitral regurgitation after surgical annulplasty is associated with posterior leaflet tethering and regurgitant severity. J Am Coll Cardiol 2011;57: E800.

355. Kuwahara E, Izumo M, Fukuoka Y, Saito T, Gurudevan SV, Tolstrup K, Siegel RJ, Tei C, Shiota T. Geometry of ischemic mitral regurgitant jet: a color doppler real- time three-dimensional echocardiography study. J Am Coll Cardiol 2011;57: E850.

356. Fukuoka Y, Izumo M, Saito T, Kuwahara E, Tanaka J, gurudevan SV, Tolstrup K, Siegel, Shiota T. Relationship between left appendage volume and function, and left Atrial function: a real-time three-dimensional transesophageal echocardiography study. Circulation 2011;124:A8856.

357. Izumo M, Kuwahara E, Fukuoka Y, Saito T, Gurudevan SV, Tolstrup K, Siegel RJ. Shiota T. Quantification of mitral valve prolapse using real-time three-dimensional transesophageal echocardiography: a comparison with two-dimensional trans- esophageal echocardiography. J Am Coll Cardiol 2011;57: E849.

358. Izumo M, Kuwahara E, Saitoh T, Fukuoka Y, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Mechanism of functional mitral regurgitation in patients with lone atrial fibrillation: A real-time three-dimensional transesophageal echocardiography study. J Am Soc Echocardiogr 2011;24:5-B21.

359. Izumo M, Saito T, Kuwahara E, Fukuoka Y, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Non-circular shape of right ventricular outflow tract: a real-time three- dimensional transesophageal echocardiography study. J Am Soc Echocardiogr 2011; 24:5-B67.

360. Izumo M, Saitoh T, Fukuoka Y, Tanaka J, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Geometric differences in right ventricular remodeling between pressure Overload and volume overload: a real-time three-dimensional transesophageal Echocardiography study. Circulation 2011;124:A13620.

361. Izumo M, Saitoh T, Fukuoka Y, Tanaka J, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Geometric differences in the mitral apparatus between ischemic cardiomyopathy and lone atrial fibrillation with significan mitral regurgitation: a real-time-three-dimensional echocardiography study. Circulation 2011;124:A17767.

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362. Izumo M, Saitoh T, Fukuoka Y, Tanaka J, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Non-circular shape of right ventricular outflow tract: a real-time three- Dimensional transesophageal echocardiography study. Circulation 2011;124:A13585.

363. Izumo M, Suzuki K, Kikuchi H, Kida K, Ko S, Eguchi Y, Akashi YJ, Omiya K, Miyake F, Shiota T. Mechanism of false positive treadmill exercise electrocardigraphy: is false positive test truly false? Euro Heart J 2011;32:325.

364. Izumo M, Kuwahara E, Fukuoka Y, Saito T, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Quantification of mitral valve prolapse by real-time three-dimensional transesophageal echocardiography: a comparison with two-dimensional transesophageal echocardiography. Euro Heart J 2011;32:1011.

365. Izumo M, Saito T, Fukuoka Y, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Non-Circular shape of right ventricular outflow tract: a real-time three-dimensional transesophageal echocardiography study. Euro Heart J 2011;32:204.

366. Perk G, Biner S, Kronzon I, Saric M, Chinitz L, Thompson K, Shiota T, Hussani A, Lang R, Siegel R, Kar S. Catheter-based left atrial appendage occlusion procedure: role of echocardiography. Eur Heart J Cardiovasc Imaging. 2012;13(2):132-8.

367. Shimada YJ, Shiota T. Underestimation of left atrial volume by three-dimensional echocardiography validated by magnetic resonance imaging: a meta-analysis and investigation of the source of bias. Echocardiography. 2012;29(4):385-90.

368. Nalawadi SS, Tolstrup K, Cuk O, Shiota T, Gurudevan SV, Siegel RJ. Atropine as an adjunct to supine bicycle stress echocardiography: an alternative strategy to achieve target heart rate or rate pressure product. Eur Heart J Cardiovasc Imaging. 2012;13(7):612-6.

369. Miyata-Fukuoka Y, Izumo M, Shimada Y, Kuwahara E, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Left atrial size and function are related to pulmonary hypertension in coronary artery disease. Echocardiography. 2012;29(5):535-40.

370. Jilaihawi H, Kashif M, Fontana G, Furugen A, Shiota T, Friede G, Makhija R, Doctor N, Leon MB, Makkar RR. Cross-sectional computed tomographic assessment improves accuracy of aortic annular sizing for transcatheter aortic valve replacement and reduces the incidence of paravalvular aortic regurgitation. J Am Coll Cardiol. 2012;59(14):1275-86.

371. Saitoh T, Shiota M, Izumo M, Gurudevan SV, Tolstrup K, Siegel RJ, Shiota T. Comparison of left ventricular outflow geometry and aortic valve area in patients with aortic stenosis by 2-dimensional versus 3-dimensional echocardiography. Am J Cardiol. 2012;109(11):1626-31.

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372. Saitoh T, Izumo M, Furugen A, Tanaka J, Miyata-Fukuoka Y, Gurudevan SV, Tolstrup K, Siegel RJ, Kar S, Shiota T. Echocardiographic evaluation of iatrogenic atrial septal defect after catheter-based mitral valve clip insertion. . Am J Cardiol. 2012;109(12):1787-91.

373. Shimada YJ, Shiota T. Meta-analysis of accuracy of left ventricular mass measurement by three-dimensional echocardiography. Am J Cardiol. 2012;110(3):445-52.

374. Shimada YJ, Ishikawa K, Kawase Y, Ladage D, Tilemann L, Shiota T, Hajjar RJ. Comparison of Left Ventricular Stroke Volume Assessment by Two- and Three-Dimensional Echocardiography in a Swine Model of Acute Myocardial Infarction Validated by Thermodilution Method. Echocardiography. 2012 June 5

375. Thompson KA, Shiota T, Tolstrup K, Gurudevan SV, Siegel RJ. Non-Circular Shape of Right Ventricular Outflow Tract: A Real-Time Three-Dimensional Transesophageal Echocardiography Study. Circ Cardiovasc Imaging. 2012 Aug 13.

376. Kazemimood R, Mirocha J, Shiota T. Clinical and echocardiographic factors that are associated with left atrial appendage thrombus or spontaneous echo contrast in patients with atrial fibrillation. J Am Coll Cardiol 2012;59:A165(1236-175).

377. Saitoh T, Tanaka J, Furugen A, Harada K, Gurudevan S, Tolstrup K, Siegel R, Shiota T. Impact of energy loss index using real-time 3-dimentional transesophageal echocardiography on assessment of aortic stenosis. J Am Coll Cardiol 2012;59:A270 (1091-15).

378. Saitoh T, Izumo M, Fukuoka Y, Furugen A, Tanaka J, Harada K, Gurudevan S, Tolstrup K, Siegel R, Kar S, Shiota T. The evaluation of Iatrogenic atrial septal defect after catheter-Based mitral valve clip repair; two-and three-dimensional echocardiography study. J Am Coll Cardiol 2012;59:A271 (1091-16).

379. Tanaka J, Saitoh T, Furugen A, Harada K, Siegel R, Shiota T. Dynamic change of patent of patent foramen ovale area: evaluation using three-dimensional transesophageal echocardiography. J Am Coll Cardiol 2012;59:A271 (1091-17).

380 Saitoh T, Shiota M, Izumo M, Fukuoka Y, Furugen A, Tanaka J, Harada K, Gurudevan S, Tolstrup K, Siegel R, Shiota T. Assessment of the left ventricular outflow tract and aortic valve area in patients with aortic stenosis; 2-dimensional and 3-dimensional echocardiography. J Am Coll Cardiol 2012;59:A308 (1094-159).

381. Saitoh T, Tanaka J, Furugen A, Harada K, Gurudevan S, Tolstrup K, Siegel R, Shiota T. Evaluation of aortic root anatomy in patients with aortic stenosis using 3- dimensional transesophageal echocardiography. J Am Coll Cardiol 2012;59:A309 (1094-162).

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382. Tanaka J, Saitoh T, Furugen A, Makkar R, Shiota T. Changes of mitral regurgitation after surgical aortic valve replacement and transcatheter aortic valve implantation: a two-dimensional echocardiography study. J Am Coll Cardiol 2012;59:A485 (1148- 192).

383. Harada K, Tanaka J, Berdejo J, Shibayama K, Shiota T. Valvuloarterial Impedance and Hypertension as Predictors of Syncope in Patients with Aortic Stenosis. J Am Coll Cardiol 2013;61(10_S):. doi:10.1016/S0735-1097(13)61939-7

384. Shibayama K, Watanabe H, Sasaki S, Mahara K, Tabata M, Fukui T, Umemura J, Takanashi S, Sumiyoshi T, Shiota T. Quantitative 3D Analysis of Aortic Valve Apparatus for Pathological Classification of Aortic Regurgitation. J Am Coll Cardiol 2013; 61(10_S):.doi: 10.1016/S0735-1097(13)60873-6

385. Shibayama K, Harada K, Tanaka J, Berdejo J, Shiota T. Comparison of Aortic Root Geometry in Patient with Bicuspid versus Tricuspid Aortic Valve: A Real-Time 3D Transesophageal Echocardiography Study. J Am Coll Cardiol 2013;61(10_S): doi: 10.1016/S0735-1097(13)62013-6

386. Tanaka J, Matsumoto T, Yeow WL, Harada K, Berdejo J, Shibayama K, Harada K, Kar S, Shiota T. Evaluation of Mitral Valve Area after MitraClip Procedure: A Real- Time 3D Transesophageal Echocardiographic Study. J Am Coll Cardiol 2013;61(10_S)E883

387. Izumo M, Kuwahara E, Saitoh T, Tanaka J, Fukuoka Y, Gurudevan SV, Siegel RJ, Shiota T. Geometric Differences in Mitral Apparatus between Different Types of Ischemic Mitral Regurgitant Jet: A Color Doppler Real-Time 3D Transesophageal Echocardiography Study. J Am Coll Cardiol 2013; 61 (10_ S) E1933 2013;61(10_S):. doi:10.1016/S0735-1097(13)61933-6.

388. Tanaka J, Matsumoto T, Yeow Wen Loong, Kenji Harada K, Javier Berdejo J, Shibayama K, Harada K, Kar S, Shiota T. Comparison of Mitral Valve Area between Single and Dual MitraClip Device Deployment: A Real-time 3-Dimensional Transesophageal Echocardiographic Study J Am Soc Echocardiogr 2013;26:B74.

389. Tanaka J, Harada K, Berdejo J, Shibayama K, Izumo M, Saitoh T, Harada K, Shiota T. Evaluation of Bubble Grade of Right to Left Shunt in Patients with Patent Foramen Ovale: A Real-time 3-Dimensional Transesophageal Echocardiographic Study. J Am Soc Echocardiogr 2013;26:B77.

390. Tanaka J, Harada K, Berdejo J, Shibayama K, Izumo M, Saitoh T, Harada K, Shiota T. Patent Foramen Ovale Parameters for Appropriate Selection of Transcatheter Closure Device: A Real-time 3-Dimensional Transesophageal Echocardiographic Study. J Am Soc Echocardiogr 2013;26:B77.

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391. Harada K, Shibayama K, Berdejo J, Shiota T. Not Aortic Stenosis Severity but High Valvuloarterial Impedance Predicts Syncope in Aortic Stenosis. J Am Soc Echocardiogr 2013;26:B15.

392. Shibayama K, Harada K, Tanaka J, Berdejo J, Shiota T. Comparison of Dynamic Motion in Aortic Annular Geometry with Bicuspid versus Tricuspid Aortic Valve: A Real-Time Three-Dimensional Transesophageal Echocardiography Study, J Am Soc Echocardiogr 2013;26:B11.

393. Berdejo J, Harada K, Shibayama K, Shiota T. Real-Time Three-Dimensional Transesophageal Echocardiography in Evaluation of Changes in Mitral Valve After Successful Surgical Repair for Severe Regurgitation. J Am Soc Echocardiogr 2013;26:B73.

394. Shibayama K, Harada K, Mihara H, Tanaka J, Berdejo J, Gurudevan SV, Siegel RJ, Jilaihawi H, Makkar R, Shiota T. Impact of Transcatheter Aortic Valve Replacement on the Mitral Valve Apparatus and Mitral Regurgitation: A Real-Time Three- Dimensional Transesophageal Echocardiography Study. Circulation. 2013;128:A13323.

395. Mihara H, Shibayama K, Harada K, Berdejo J, Gurudevan SV, Siegel RJ, Jilaihawi H, Makkar R, Shiota T. Impact of Aortic Valve and Annular Calcification on Paravalvular Aortic Regurgitation After Transcatheter Aortic Valve Replacement: A Real-Time Three-Dimensional Transesophageal Echocardiography Study. Circulation. 2013;128:A14317.

396. Berdejo J, Harada K, Shibayama K, Mihara H, Shiota T. Real-time Three- dimensional Transesophageal Echocardiography Identifies the Association Between a Small Posterior Leaflet and a Pseudoprolapse of Anterior Leaflet in Eccentric Functional Mitral Regurgitation. Circulation. 2013;128:A14229.

397. Mihara H, Shibayama K, Harada K, Berdejo J, Itabashi Y, Siegel R, Jilaihawi H, Makkar R, Shiota T, Value of Holodiastolic Flow Reversal in the Descending Aorta in Patients with Post-Procedural Aortic Regurgitation after Transcatheter Aortic Valve Replacement: An Intraoperative Transesophageal Echocardiography Study. J Am Coll Cardiol. 2014;63:supple A492

398. Mihara H, Shibayama K, Harada K, Berdejo J, Itabashi Y, Siegel R, Jilaihawi H, Makkar R, Shiota T, Impact of Device Landing Zone Calcification on Paravalvular Aortic Regurgitation after Transcatheter Aortic Valve Replacement: A Real-Time Three-Dimensional Transesophageal Endocardiography Study. J Am Coll Cardiol. 2014;63: supple A247

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399. Itabashi Y, Shibayama K, Mihara H, Berdejo J, Siegel R, Jilaihawi H, Makkar R, Shiota T, Relationship between Mitral Regurgitation and Left Ventricular Ejection Fraction and Stroke Volume after Transcatheter Aortic Valve Replacement. J Am Coll Cardiol. 2014; 63: supple A248

400. Mihara H, Berdejo J, Itabashi Y, DeRobertis MA, Trento A, Shiota T. Impact of Paravalvular Regurgitation after Surgical Aortic Valve Replacement: An Intraoperative Transesophageal Echocardiography Study. J Am Soc Echocardiogr. 2014;27:B11

401. Itabashi Y, Berdejo J, Mihara H, Shiota T. Morphological Mechanisms of Mitral Valve Pseudoprolapse in Atrial Fibrillation Patients: A Real-Time Three- Dimensional Transesophageal Echocardiography Study. J Am Soc Echocardiogr. 2014; 27: B21

402. Itabashi Y, Berdejo J, Mihara H, Shiota T. Morphological Abnormality of the Mitral Valve Causing Significant Mitral Regurgitation in Atrial Fibrillation Patients with Preserved Left Ventricular Function: A Real-Time Three-Dimensional Transesophageal Echocardiography Study. J Am Soc Echocardiogr. 2014; 27: B98

403. Utsunomiya H, Mihara H, Itabashi Y, Berdejo J, Matsuoka K, Siegel RJ, Kashif M, Al- Jilaihawi H, Makkar RR, Shiota T. Predictors of Improvement of Left Ventricular Diastolic Function After Transcatheter Aortic Valve Replacement in Severe Aortic Stenosis With Preserved Left Ventricular Systolic Function: A Serial Echocardiographic Study. AHA, Nov. 2014.

404. Itabashi Y, Mihara H, Berdejo J, Utsunomiya H, Matsuoka K, Shiota T. Absence of Chordae Tendineae near A Coaptation Lead to Mitral Regurgitation in Lone Atrial Fibrillation Patient. AHA, Nov. 2014.

405. Mihara H, Shibayama K, Jilaihawi H, Itabashi Y, Berdejo J, Utsunomiya H, Siegel RJ, Makkar RR, Shiota T. Assessment of Post-Procedural Aortic Regurgitation after Transcatheter Aortic Valve Replacement during the Procedure: An Intraprocedural Transesophageal Echocardiography Study. AHA, Nov. 2014

406. Mihara H, Berdejo J, Itabashi Y, Utsunomiya H, De Robertis MA, Trento A, Shiota T. Impact of Paravalvular Regurgitation after Surgical Aortic Valve Replacement in Patients with Aortic Stenosis: An Intraoperative Transesophageal Echocardiography Study, AHA Nov. 2014.

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