Rabbit Anti-Human DAPP1 (Phospho-Tyr139) Polyclonal Antibody (CABT-L3484) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Rabbit Anti-Human DAPP1 (Phospho-Tyr139) polyclonal antibody (CABT-L3484) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Rabbit Anti-Human GR (Phospho-Ser226) polyclonal antibody. This antibody detects endogenous levels of DAPP1 only when phosphorylated at Tyr139.

Specificity Target Modification: Phospho. Modification Sites: Human: Y139; Mouse: Y139

Target Human DAPP1 (Phospho-Tyr139)

Immunogen The antiserum was produced against synthesized peptide derived from human DAPP1 around the phosphorylation site of Tyr139. Immunogen range: 105-154

Isotype IgG

Source/Host Rabbit

Species Reactivity Human, Mouse

Purification Affinity Purified

Conjugate Unconjugated

Applications WB, IF, ELISA

Molecular Weight 32 kDa

Preparation The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Format Liquid

Concentration Lot specific

Buffer Rabbit IgG in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl and 50% glycerol.

Preservative 0.02% Sodium Azide

Storage Stable at -20°C for at least 1 year.

Ship Wet ice

Warnings For research use only.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Introduction May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K. Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide is a protein that in humans is encoded by the DAPP1 gene. 0The function about DAPP1 antigen include phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phospholipid binding; protein tyrosine phosphatase activity.

Keywords DAPP1;dual adaptor of phosphotyrosine and 3-phosphoinositides;BAM32;dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide;hDAPP1;B-cell adapter molecule of 32 kDa;b lymphocyte adapter protein Bam32;

GENE INFORMATION

Gene Name DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides [ Homo sapiens (human) ]

Official Symbol DAPP1

Entrez Gene ID 27071

UniProt ID Q9UN19

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]