Annexes of the Annual Report 2011
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Transnational Open Teams Rosters 2013 World Bridge Team
2013 World Bridge Team Championships Bali, Indonesia Transnational Open Teams Rosters 88 GREEN BUDIHARDJO Budihardjo Indonesia JAMES James Rianto S. Indonesia SUBARI Uba Subari Indonesia SUDIRAHARDJO Liliek Indonesia SUHARYO Kristanto Indonesia ZAMAN Herry Indonesia 88 RED HERDIAN Herry Indonesia HIKMAT Kikik Indonesia IBRADI Benny J. Indonesia NURHALIM Apin Indonesia RAMADI Isman Indonesia TAMPUBOLON Baharuddin Indonesia 88 YELLOW DORISA Dorisa Indonesia KORI M. Achyan Indonesia KORI Adriansyah Indonesia MIER VALDES Valdes Indonesia MUKTI Insan R. Indonesia WINARNO Bambang Winarno Indonesia AIRLANGGA UNIVERSITY BUDIONO Welly Agus Indonesia KHIKMIA Lailatul Indonesia PRAYUDHA Bagus Tri Indonesia RAMADHAN Muhammad Indonesia 27 September 2013 Page 1 of 22 ANZAC DJUROVIC Nevena Australia HARSANYI Josef Germany HAVAS Elizabeth Australia NEWTON Shirley New Zealand WILKINSON Jenny New Zealand YUEN Michael Canada ASINDO INDONESIA BAKTI Mukhiban Darma Indonesia BOJOH Jemmy Indonesia GONTHA Leslie Indonesia HUTAHEAN David Indonesia SYAFRUDDIN Toto Indonesia WATULINGAS Giovanni Indonesia ASINDO MAKASSAR ABDULLAH Ilham Indonesia ALI Syahrial Indonesia KANDOUW Reky Indonesia LIENANDA Erwin Indonesia MANOPPO Hendrik Victor Indonesia PANGKEREGO Very Indonesia ASINDO YOUTH ANISA Hafizah Indonesia LONTOH Prillya Indonesia WATULINGAS Jennifer M H Indonesia WIBOWO Effi Indonesia 27 September 2013 Page 2 of 22 AUSTRALIA YOUTH HARRISON Shane Australia HENBEST Maxim Australia HOWARD Justin Australia MOSKOVSKY Ellena Australia THOMPSON Jamie Australia WILLIAMS -
Homozygous Familial Hypercholesterolemia - Juxtapid® (Lomitapide Capsules)
Cigna National Formulary Coverage Policy Prior Authorization Homozygous Familial Hypercholesterolemia - Juxtapid® (lomitapide capsules) Table of Contents Product Identifer(s) National Formulary Medical Necessity ................ 1 52036 Conditions Not Covered....................................... 3 Background .......................................................... 3 References .......................................................... 4 Revision History ................................................... 4 INSTRUCTIONS FOR USE The following Coverage Policy applies to health benefit plans administered by Cigna Companies. Certain Cigna Companies and/or lines of business only provide utilization review services to clients and do not make coverage determinations. References to standard benefit plan language and coverage determinations do not apply to those clients. Coverage Policies are intended to provide guidance in interpreting certain standard benefit plans administered by Cigna Companies. Please note, the terms of a customer’s particular benefit plan document [Group Service Agreement, Evidence of Coverage, Certificate of Coverage, Summary Plan Description (SPD) or similar plan document] may differ significantly from the standard benefit plans upon which these Coverage Policies are based. For example, a customer’s benefit plan document may contain a specific exclusion related to a topic addressed in a Coverage Policy. In the event of a conflict, a customer’s benefit plan document always supersedes the information in the Coverage Policies. In the absence of a controlling federal or state coverage mandate, benefits are ultimately determined by the terms of the applicable benefit plan document. Coverage determinations in each specific instance require consideration of 1) the terms of the applicable benefit plan document in effect on the date of service; 2) any applicable laws/regulations; 3) any relevant collateral source materials including Coverage Policies and; 4) the specific facts of the particular situation. -
A Novel Therapeutic Drug for the Treatment of Familial Hypercholesterolemia, Hyperlipidaemia, and Hypercholesterolemia
International Journal of Pharmacy and Pharmaceutical Sciences ISSN- 0975-1491 Vol 8, Issue 3, 2016 Review Article MIPOMERSEN: A NOVEL THERAPEUTIC DRUG FOR THE TREATMENT OF FAMILIAL HYPERCHOLESTEROLEMIA, HYPERLIPIDAEMIA, AND HYPERCHOLESTEROLEMIA AJAY KUMAR1, ARUN ACHARYA2, DINOBANDHU NANDI3, NEHA SHARMA4, EKTA CHITKARA1* 1Department of Paramedical Sciences, Lovely Professional University, Phagwara-144411, Punjab (India) Email: [email protected] Received: 25 Dec 2015 Revised and Accepted: 13 Jan 2016 ABSTRACT Familial Hypercholesterolemia (FH) is one of the most common autosomal dominant disorders which exist in either heterozygous form or a homozygous form. These two forms are prevalent in 1 in 500 and 1 in a million population respectively. FH results in premature atherosclerosis; as early as childhood in case of homozygous (HoFH) form and in adults in case of heterozygous (HeFH) form. In case of HoFH both the alleles for LDL- receptor are defective, whereas the mutation in the single allele is the cause for HeFH. Both the forms of the disease are associated with high levels of LDL-C and lipoprotein (a) in plasma, with high morbidity and mortality rate caused by cardiovascular disease. In several past years, different lipid-lowering drugs like Statins (HMG-coenzyme-A reductase inhibitor), MTTP inhibitor, CETP inhibitors, PCSK9 inhibitor, thyroid mimetics, niacin, bile acid sequestrants and lipid apheresis were administered to patients with FH, to achieve the goal of reducing plasma LDL-C and lipoprotein (a). However, such drugs proved inefficient to achieve the goals because of several reasons. Mipomersen is a 20 nucleotide antisense oligonucleotide; a novel lipid-lowering therapeutic drug currently enrolled in the treatment of patients with HoFH, HeFH and other forms of hypercholesterolemia. -
Lipid Lowering Drugs and Inflammatory Changes: an Impact on Cardiovascular Outcomes?
Annals of Medicine ISSN: 0785-3890 (Print) 1365-2060 (Online) Journal homepage: http://www.tandfonline.com/loi/iann20 Lipid Lowering Drugs and Inflammatory Changes: an Impact on Cardiovascular Outcomes? M. Ruscica, N. Ferri, C. Macchi, A. Corsini & C. R. Sirtori To cite this article: M. Ruscica, N. Ferri, C. Macchi, A. Corsini & C. R. Sirtori (2018): Lipid Lowering Drugs and Inflammatory Changes: an Impact on Cardiovascular Outcomes?, Annals of Medicine, DOI: 10.1080/07853890.2018.1498118 To link to this article: https://doi.org/10.1080/07853890.2018.1498118 Accepted author version posted online: 06 Jul 2018. Submit your article to this journal View Crossmark data Full Terms & Conditions of access and use can be found at http://www.tandfonline.com/action/journalInformation?journalCode=iann20 LIPID LOWERING DRUGS AND INFLAMMATORY CHANGES: AN IMPACT ON CARDIOVASCULAR OUTCOMES? M. Ruscica1*, N. Ferri2*, C. Macchi1, A. Corsini1 and C. R. Sirtori3 1Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Milan, Italy; 2Dipartimento di Scienze del Farmaco, Università degli Studi di Padova, Padova, Italy; 3Centro Dislipidemie, A.S.S.T. Grande Ospedale Metropolitano Niguarda, Milan, Italy *Both authors contributed equally to this work Corresponding Author: Cesare R. Sirtori [email protected] Abstract Inflammatory changes are responsible for maintenance of the atherosclerotic process and may underlie some of the most feared vascular complications. Among the multiple mechanisms of inflammation, the arterial deposition of lipids and particularly of cholesterol crystals is the one responsible for activation of inflammasome NLRP3, followed by the rise of circulating markers, mainly C-reactive protein (CRP). Elevation of lipoproteins, LDL but also VLDL and remnants, associates with increased inflammatory changes and coronary risk. -
Upregulation of Peroxisome Proliferator-Activated Receptor-Α And
Upregulation of peroxisome proliferator-activated receptor-α and the lipid metabolism pathway promotes carcinogenesis of ampullary cancer Chih-Yang Wang, Ying-Jui Chao, Yi-Ling Chen, Tzu-Wen Wang, Nam Nhut Phan, Hui-Ping Hsu, Yan-Shen Shan, Ming-Derg Lai 1 Supplementary Table 1. Demographics and clinical outcomes of five patients with ampullary cancer Time of Tumor Time to Age Differentia survival/ Sex Staging size Morphology Recurrence recurrence Condition (years) tion expired (cm) (months) (months) T2N0, 51 F 211 Polypoid Unknown No -- Survived 193 stage Ib T2N0, 2.41.5 58 F Mixed Good Yes 14 Expired 17 stage Ib 0.6 T3N0, 4.53.5 68 M Polypoid Good No -- Survived 162 stage IIA 1.2 T3N0, 66 M 110.8 Ulcerative Good Yes 64 Expired 227 stage IIA T3N0, 60 M 21.81 Mixed Moderate Yes 5.6 Expired 16.7 stage IIA 2 Supplementary Table 2. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis of an ampullary cancer microarray using the Database for Annotation, Visualization and Integrated Discovery (DAVID). This table contains only pathways with p values that ranged 0.0001~0.05. KEGG Pathway p value Genes Pentose and 1.50E-04 UGT1A6, CRYL1, UGT1A8, AKR1B1, UGT2B11, UGT2A3, glucuronate UGT2B10, UGT2B7, XYLB interconversions Drug metabolism 1.63E-04 CYP3A4, XDH, UGT1A6, CYP3A5, CES2, CYP3A7, UGT1A8, NAT2, UGT2B11, DPYD, UGT2A3, UGT2B10, UGT2B7 Maturity-onset 2.43E-04 HNF1A, HNF4A, SLC2A2, PKLR, NEUROD1, HNF4G, diabetes of the PDX1, NR5A2, NKX2-2 young Starch and sucrose 6.03E-04 GBA3, UGT1A6, G6PC, UGT1A8, ENPP3, MGAM, SI, metabolism -
AOAC Europe NMKL Nordval Symposium
AOAC EUROPE - NMKL - NordVal 7 – 8 May 2012 RAPID METHODS AOAC EUROPE ‐ NMKL‐ NordVal Welcome to the Internaonal Symposium on Rapid Methods chemical, microbiological and sensory analysis of foods IDA Meeng Centre, Kalvebod Brygge 31‐33, Copenhagen, Denmark NMKL, Nordic Commiee on Food Analysis, www.nmkl.org, Email: [email protected] c/o Norwegian Veterinary Instute, P.O.Box 750, Sentrum, N‐0106 Oslo, Norway 1 EUROPE SECTION OF AOAC INTERNATIONAL NordVal performs a third‐party review and AOAC Europe is a secon of AOAC INTERNATIONAL cerfies alternave chemical and and was established in 1989. It is an organizaon of professional sciensts that exchange knowledge microbiological methods for food, and informaon to help each other excel in their feed, water, faeces and profession. environmental tesng. The acvies of the secon are of interest to many NordVal offers: stakeholders from industry and trade, consumer a user‐friendly validaon and environmental protecon agencies, public au‐ protocol thories and regulators in Europe and/or Mediter‐ scienfic confirmaon policies ranean countries. specified acceptance criteria www.aoaceurope.com independent and rapid approval procedures guidance in the validaon NMKL offers process reliable analycal methods within chemical, microbiological and sensorial methods independent reviews and NordVal cerficaons of proprietary and other The Nordic Commiee on Food alternave methods Analysis, NMKL, was founded in 1947 and consists of chemists, relevant guidelines microbiologists, sensory analysts courses/workshops/seminars and stascians from the five Nordic countries, Denmark Finland, network of analycal experts Iceland, Norway and Sweden. updated list of contact persons of the naonal reference laboratories within the NMKL is linked to the Nordic Nordic countries Council of Ministers. -
Bovine Coccidiosis - a Review
PEER REVIEWED Bovine Coccidiosis - A Review DL Step, DVM, DACVIM; RN Streeter, DVM, MS, DACVIM; JG Kirkpatrick, DVM, DABVP Department of Veterinary Clinical Sciences, Boren Veterinary Teaching Hospital, Oklahoma State University, Stillwater, OK 74078 Abstract mune en hiver meme dans les cas de confinement. Les :feces peuvent contenir des oocystes meme lorsque les Coccidians are protozoa! parasites that are host animaux ne montrent pas de signes cliniques de sorte specific, transmitted by the fecal-oral route and cause qu'un diagnostic de coccidiose doit se baser sur les signes enteritis. Economically significant species discussed in cliniques et exclure les autres maladies. L'identification this paper that cause disease in cattle belong to the ge post-mortem de coccidies aide a supporter le diagnostic. nus Eimeria. Young animals are more susceptible to Les elements de regie qui reduisent le stress et clinical disease than older cattle. Coccidiosis is fre previennent la contamination de l'eau et de la nourriture quently observed in stressed, overcrowded and confined sont importants pour prevenir la coccidiose. Les conditions, however, .the disease can occur on pasture. programmes de controle efficaces incluent souvent The disease can occur any time of the year but is more !'utilisation de nourriture et d'eau medicamentes. Les prevalent during winter months, even in confinement agents antimicrobiens couramment utilises aux Etats operations. Animals may pass oocysts in their feces with Unis pour le controle et la prevention de coccidiose out clinical disease, therefore, a diagnosis of coccidiosis incluent entre autres le monensin, le lasalocide, le is based on clinical signs and ruling out other diseases. -
Role of Bile Acids in the Regulation of Food Intake, and Their Dysregulation in Metabolic Disease
nutrients Review Role of Bile Acids in the Regulation of Food Intake, and Their Dysregulation in Metabolic Disease Cong Xie 1,† , Weikun Huang 1,2,† , Richard L. Young 1,3 , Karen L. Jones 1,4 , Michael Horowitz 1,4, Christopher K. Rayner 1,5 and Tongzhi Wu 1,4,6,* 1 Adelaide Medical School, Center of Research Excellence (CRE) in Translating Nutritional Science to Good Health, The University of Adelaide, Adelaide 5005, Australia; [email protected] (C.X.); [email protected] (W.H.); [email protected] (R.L.Y.); [email protected] (K.L.J.); [email protected] (M.H.); [email protected] (C.K.R.) 2 The ARC Center of Excellence for Nanoscale BioPhotonics, Institute for Photonics and Advanced Sensing, School of Physical Sciences, The University of Adelaide, Adelaide 5005, Australia 3 Nutrition, Diabetes & Gut Health, Lifelong Health Theme South Australian Health & Medical Research Institute, Adelaide 5005, Australia 4 Endocrine and Metabolic Unit, Royal Adelaide Hospital, Adelaide 5005, Australia 5 Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, Adelaide 5005, Australia 6 Institute of Diabetes, School of Medicine, Southeast University, Nanjing 210009, China * Correspondence: [email protected] † These authors contributed equally to this work. Abstract: Bile acids are cholesterol-derived metabolites with a well-established role in the digestion and absorption of dietary fat. More recently, the discovery of bile acids as natural ligands for the nuclear farnesoid X receptor (FXR) and membrane Takeda G-protein-coupled receptor 5 (TGR5), and Citation: Xie, C.; Huang, W.; Young, the recognition of the effects of FXR and TGR5 signaling have led to a paradigm shift in knowledge R.L.; Jones, K.L.; Horowitz, M.; regarding bile acid physiology and metabolic health. -
Report Name:Ukraine's Mrls for Veterinary Drugs
Voluntary Report – Voluntary - Public Distribution Date: November 05,2020 Report Number: UP2020-0051 Report Name: Ukraine's MRLs for Veterinary Drugs Country: Ukraine Post: Kyiv Report Category: FAIRS Subject Report Prepared By: Oleksandr Tarassevych Approved By: Robin Gray Report Highlights: Ukraine adopted several maximum residue levels (MRLs) for veterinary drugs, coccidiostats and histomonostats in food products of animal origin. Ukraine also adopted a list of drugs residues that are not allowed in food products. THIS REPORT CONTAINS ASSESSMENTS OF COMMODITY AND TRADE ISSUES MADE BY USDA STAFF AND NOT NECESSARILY STATEMENTS OF OFFICIAL U.S. GOVERNMENT POLICY The Office of Agricultural Affairs of USDA/Foreign Agricultural Service in Kyiv, Ukraine prepared this report for U.S. exporters of domestic food and agricultural products. While every possible care was taken in the preparation of this report, information provided may not be completely accurate either because policies have changed since the time this report was written, or because clear and consistent information about these policies was not available. It is highly recommended U.S. exporters verify the full set of import requirements with their foreign customers, who are normally best equipped to research such matters with local authorities, before any goods are shipped. This FAIRS Subject Report accompanies other reports on Maximum, Residue Limits established by Ukraine in 2020. Related reports could be found under the following links: 1.) Ukraine's MRLs for Microbiological Contaminants_Kyiv_Ukraine_04-27-2020 2.) Ukraine's MRLs for Certain Contaminants_Kyiv_Ukraine_03-06-2020 Food Products of animal origin and/or ingredients of animal origin are not permitted in the Ukrainian market if they contain certain veterinary drugs residues in excess of the maximum residue levels established in Tables 1 and 2. -
)&F1y3x PHARMACEUTICAL APPENDIX to THE
)&f1y3X PHARMACEUTICAL APPENDIX TO THE HARMONIZED TARIFF SCHEDULE )&f1y3X PHARMACEUTICAL APPENDIX TO THE TARIFF SCHEDULE 3 Table 1. This table enumerates products described by International Non-proprietary Names (INN) which shall be entered free of duty under general note 13 to the tariff schedule. The Chemical Abstracts Service (CAS) registry numbers also set forth in this table are included to assist in the identification of the products concerned. For purposes of the tariff schedule, any references to a product enumerated in this table includes such product by whatever name known. Product CAS No. Product CAS No. ABAMECTIN 65195-55-3 ACTODIGIN 36983-69-4 ABANOQUIL 90402-40-7 ADAFENOXATE 82168-26-1 ABCIXIMAB 143653-53-6 ADAMEXINE 54785-02-3 ABECARNIL 111841-85-1 ADAPALENE 106685-40-9 ABITESARTAN 137882-98-5 ADAPROLOL 101479-70-3 ABLUKAST 96566-25-5 ADATANSERIN 127266-56-2 ABUNIDAZOLE 91017-58-2 ADEFOVIR 106941-25-7 ACADESINE 2627-69-2 ADELMIDROL 1675-66-7 ACAMPROSATE 77337-76-9 ADEMETIONINE 17176-17-9 ACAPRAZINE 55485-20-6 ADENOSINE PHOSPHATE 61-19-8 ACARBOSE 56180-94-0 ADIBENDAN 100510-33-6 ACEBROCHOL 514-50-1 ADICILLIN 525-94-0 ACEBURIC ACID 26976-72-7 ADIMOLOL 78459-19-5 ACEBUTOLOL 37517-30-9 ADINAZOLAM 37115-32-5 ACECAINIDE 32795-44-1 ADIPHENINE 64-95-9 ACECARBROMAL 77-66-7 ADIPIODONE 606-17-7 ACECLIDINE 827-61-2 ADITEREN 56066-19-4 ACECLOFENAC 89796-99-6 ADITOPRIM 56066-63-8 ACEDAPSONE 77-46-3 ADOSOPINE 88124-26-9 ACEDIASULFONE SODIUM 127-60-6 ADOZELESIN 110314-48-2 ACEDOBEN 556-08-1 ADRAFINIL 63547-13-7 ACEFLURANOL 80595-73-9 ADRENALONE -
Maja Lunde Klaus Hagerup Maria Parr
Children - Novels Maja Lunde The Snow Sister (Snøsøsteren) Illustrated novel | Kagge Forlag | 2018 October | 190 pages Bringing you the Magic of Christmas! The History of Bees-author Maja Lunde and award winning illustrator Lisa Aisato have created an unforgettable story in 24 short chapters which reflects the feeling of Christmas you recognize from Charles Dickens’ A Christmas Carol and stories by H.C. Andersen. Oslo Literary Agency : Evy Tillman ; [email protected] ; +47 952 24 408 ; www.osloliteraryagency.no So far sold to: Belarusian, Bulgarian, Catalan, Chinese simplified, Croatian, Czech, Danish, Estonian, Faroese, Finnish, Georgian, German, Greek, Hungarian, Icelandic, Italian, Korean, Latvian, Lithuanian, Polish, Romanian, Russian, Slovakian, Slovene, Spanish, Swedish, Turkish, Ukrainian Film rights: Anonymous Content Klaus Hagerup The Girl Who Wanted to Save the Books (Jenta som ville redde bøkene) Picture Book | Gyldendal | 2017 | 55 pages Anna is nearly 10 years old and loves to read. She loves reading so much that one of her best friends is the librarian, Monsen. One day Monsen tells Anna what happens to the books no one wants to borrow from the library. The books disappear. The books are destroyed. But what happens to all those who live inside these books, Anna wonders? Do they disappear too? This is just too much to bear, Anna thinks. She has to save the books! But how? Illustrated by Lisa Aisato. Oslo Literary Agency | [email protected] | www.osloliteraryagency.no So far sold to: Braz. Portuguese, Chinese (simplified), Czech, Danish, Estonian, Georgian, German, Greek, Hungarian, Icelandic, Italian, Korean, Latvian, Lithuanian, Persian, Polish, Portuguese, Romanian, Russian, Spanish, Catalan, Portuguese, Swedish, Turkish, Ukrainian Maria Parr The Goalie and the Sea (Keeperen og havet) Novel | Samlaget | 2017 | 234 pages The arrival of a new football coach means dark clouds are looming over twelve-year-old Lena Lid’s goalkeeping career. -
Anti-Infectives Industry Over the Next 5 Years and Beyond
Bridging the innovation gap... New Drug Futures: Products that could change the pharma market to 2013 and beyond Over 70 pipeline prospects This new major and insightful 450 page in 8 major therapy areas analysis evaluates, compares and contrasts the are analysed in this report prospects for the development compounds that could revolutionise the pharmaceutical Anti-infectives industry over the next 5 years and beyond. Cardiovascular CNS The report provides: Gastrointestinal Detailed background and market context for Metabolic each therapy area covered: Musculoskeletal Addressable patient population Oncology Current treatments Sales drivers Respiratory Sales breakers Future treatments Market dynamics – winners and losers Key drug launches by 2013 Unique sales forecasts by major product to 2013 Over 70 key products assessed Unique evaluation scores for key areas such as novelty of mechanism, clinical data and competition Critical and detailed appraisal of each product‟s research and development Extensive pipeline listings, putting the profiled products into their competitive context The search – and need – for new products has never been greater and what’s in the development pipeline has never generated more interest. That is why this analysis is so important! GLOBAL PHARMA MARKET IN CONTEXT THE Are there too many prophets of doom ready to write-off the research-based pharma industry in the future? Too few novel There is plenty on which to base such anxiety. The research-based industry products and an must achieve a fair price in the face of greater cost control, while the aggressive generic burden of regulation is setting the bar high for successful product sector are taking introduction.