N6AMT1 / HEMK2 (1-214, His-Tag) Human Protein – AR51691PU-N

OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for AR51691PU-N

N6AMT1 / HEMK2 (1-214, His-tag) Human Protein Product data:

Product Type: Recombinant Proteins Description: N6AMT1 / HEMK2 (1-214, His-tag) human recombinant protein, 0.1 mg Species: Human Expression Host: E. coli Tag: His-tag Predicted MW: 25.3 kDa Concentration: lot specific Purity: >85% by SDS - PAGE Buffer: Presentation State: Purified Buffer System: Liquid, In Phosphate buffered saline (pH7.4) containing 20% glycerol, 1mM DTT. Protein Description: Recombinant human N6ATM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Storage: Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Stability: Shelf life: one year from despatch. RefSeq: NP_037372 Locus ID: 29104 UniProt ID: Q9Y5N5 Cytogenetics: 21q21.3 Synonyms: C21orf127; HEMK2; KMT9; m.HsaHemK2P; MTQ2; N6AMT; PRED28; PrmC Summary: This gene encodes an N(6)-adenine-specific DNA methyltransferase. The encoded enzyme may be involved in the methylation of release factor I during translation termination. This enzyme is also involved in converting the arsenic metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid. Alternative splicing pf this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Jul 2014] Protein Families: Druggable Genome

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