Celebrating Years of 60Science Welcome to the 60Th Anni- Versary Symposium of the Miller Institute
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Applied Category Theory for Genomics – an Initiative
Applied Category Theory for Genomics { An Initiative Yanying Wu1,2 1Centre for Neural Circuits and Behaviour, University of Oxford, UK 2Department of Physiology, Anatomy and Genetics, University of Oxford, UK 06 Sept, 2020 Abstract The ultimate secret of all lives on earth is hidden in their genomes { a totality of DNA sequences. We currently know the whole genome sequence of many organisms, while our understanding of the genome architecture on a systematic level remains rudimentary. Applied category theory opens a promising way to integrate the humongous amount of heterogeneous informations in genomics, to advance our knowledge regarding genome organization, and to provide us with a deep and holistic view of our own genomes. In this work we explain why applied category theory carries such a hope, and we move on to show how it could actually do so, albeit in baby steps. The manuscript intends to be readable to both mathematicians and biologists, therefore no prior knowledge is required from either side. arXiv:2009.02822v1 [q-bio.GN] 6 Sep 2020 1 Introduction DNA, the genetic material of all living beings on this planet, holds the secret of life. The complete set of DNA sequences in an organism constitutes its genome { the blueprint and instruction manual of that organism, be it a human or fly [1]. Therefore, genomics, which studies the contents and meaning of genomes, has been standing in the central stage of scientific research since its birth. The twentieth century witnessed three milestones of genomics research [1]. It began with the discovery of Mendel's laws of inheritance [2], sparked a climax in the middle with the reveal of DNA double helix structure [3], and ended with the accomplishment of a first draft of complete human genome sequences [4]. -
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MICHAEL GERRARD ‘72 COLLEGE HONORS FIVE IS THE GURU OF DISTINGUISHED ALUMNI CLIMATE CHANGE LAW WITH JOHN JAY AWARDS Page 26 Page 18 Columbia College May/June 2011 TODAY Nobel Prize-winner Martin Chalfie works with College students in his laboratory. APassion for Science Members of the College’s science community discuss their groundbreaking research ’ll meet you for a I drink at the club...” Meet. Dine. Play. Take a seat at the newly renovated bar grill or fine dining room. See how membership in the Columbia Club could fit into your life. For more information or to apply, visit www.columbiaclub.org or call (212) 719-0380. The Columbia University Club of New York 15 West 43 St. New York, N Y 10036 Columbia’s SocialIntellectualCulturalRecreationalProfessional Resource in Midtown. Columbia College Today Contents 26 20 30 18 73 16 COVER STORY ALUMNI NEWS DEPARTMENTS 2 20 A PA SSION FOR SCIENCE 38 B OOKSHELF LETTERS TO THE Members of the College’s scientific community share Featured: N.C. Christopher EDITOR Couch ’76 takes a serious look their groundbreaking work; also, a look at “Frontiers at The Joker and his creator in 3 WITHIN THE FA MILY of Science,” the Core’s newest component. Jerry Robinson: Ambassador of By Ethan Rouen ’04J, ’11 Business Comics. 4 AROUND THE QU A DS 4 Reunion, Dean’s FEATURES 40 O BITU A RIES Day 2011 6 Class Day, 43 C L A SS NOTES JOHN JA Y AW A RDS DINNER FETES FIVE Commencement 2011 18 The College honored five alumni for their distinguished A LUMNI PROFILES 8 Senate Votes on ROTC professional achievements at a gala dinner in March. -
Masthead (PDF)
Proceedings of the National Academy ofPNAS Sciences of the United States of America www.pnas.org PRESIDENT OF Robert G. Roeder Geophysics John J. Mekalanos THE ACADEMY Michael Rosbash Michael L. Bender Peter Palese Ralph J. Cicerone David D. Sabatini Thomas E. Shenk Gertrud M. Schupbach Human Environmental Thomas J. Silhavy SENIOR EDITOR Robert Tjian Sciences Peter K. Vogt Solomon H. Snyder Susan Hanson Cellular and Molecular Physics ASSOCIATE EDITORS Neuroscience Immunology Anthony Leggett William C. Clark Pietro V. De Camilli Peter Cresswell Paul C. Martin Alan Fersht Richard L. Huganir Douglas T. Fearon Jack Halpern L. L. Iversen Richard A. Flavell Physiology and Jeremy Nathans Charles F. Stevens Dan R. Littman Pharmacology Thomas C. Su¨dhof Tak Wah Mak Susan G. Amara Joseph S. Takahashi William E. Paul David Julius EDITORIAL BOARD Hans Thoenen Michael Sela Ramon Latorre Ralph M. Steinman Masashi Yanagisawa Animal, Nutritional, and Chemistry Applied Microbial Sciences Stephen J. Benkovic Mathematics Plant Biology David L. Denlinger Bruce J. Berne Richard V. Kadison Maarten J. Chrispeels R. Michael Roberts Harry B. Gray Robion C. Kirby Enrico Coen Robert Haselkorn Linda J. Saif Mark A. Ratner George H. Lorimer Ryuzo Yanagimachi Barry M. Trost Medical Genetics, Hematology, and Nicholas J. Turro Anthropology Oncology Plant, Soil, and Charles T. Esmon Microbial Sciences Jeremy A. Sabloff Computer and Joseph L. Goldstein Roger N. Beachy Information Sciences Mark T. Groudine Steven E. Lindow Applied Mathematical Sciences Shafrira Goldwasser David O. Siegmund Tony Hunter M. S. Swaminathan Philip W. Majerus Susan R. Wessler Economic Sciences Newton E. Morton Applied Physical Sciences Ronald W. -
CURRICULUM VITAE George M. Weinstock, Ph.D
CURRICULUM VITAE George M. Weinstock, Ph.D. DATE September 26, 2014 BIRTHDATE February 6, 1949 CITIZENSHIP USA ADDRESS The Jackson Laboratory for Genomic Medicine 10 Discovery Drive Farmington, CT 06032 [email protected] phone: 860-837-2420 PRESENT POSITION Associate Director for Microbial Genomics Professor Jackson Laboratory for Genomic Medicine UNDERGRADUATE 1966-1967 Washington University EDUCATION 1967-1970 University of Michigan 1970 B.S. (with distinction) Biophysics, Univ. Mich. GRADUATE 1970-1977 PHS Predoctoral Trainee, Dept. Biology, EDUCATION Mass. Institute of Technology, Cambridge, MA 1977 Ph.D., Advisor: David Botstein Thesis title: Genetic and physical studies of bacteriophage P22 genomes containing translocatable drug resistance elements. POSTDOCTORAL 1977-1980 Postdoctoral Fellow, Department of Biochemistry TRAINING Stanford University Medical School, Stanford, CA. Advisor: Dr. I. Robert Lehman. ACADEMIC POSITIONS/EMPLOYMENT/EXPERIENCE 1980-1981 Staff Scientist, Molec. Gen. Section, NCI-Frederick Cancer Research Facility, Frederick, MD 1981-1983 Staff Scientist, Laboratory of Genetics and Recombinant DNA, NCI-Frederick Cancer Research Facility, Frederick, MD 1981-1984 Adjunct Associate Professor, Department of Biological Sciences, University of Maryland, Baltimore County, Catonsville, MD 1983-1984 Senior Scientist and Head, DNA Metabolism Section, Lab. Genetics and Recombinant DNA, NCI-Frederick Cancer Research Facility, Frederick, MD 1984-1990 Associate Professor with tenure (1985) Department of Biochemistry -
Annual Report 2009–2010 Columbia University Columbia 2009–2010 Report Annual Nstitute
WEATHERHEAD ANNUAL REPORT 2009 – 2 010 E AST A SIAN I NSTITUTE ANNUAL REPORT 2009–2010 COLUMBIA UNIVERSITY Weatherhead East Asian Institute Columbia University International Affairs Building, 9th floor MC 3333 420 West 118th Street New York, NY 10027 Tel: 212-854-2592 Fax: 212-749-1497 www.columbia.edu/weai TABLE OF CONTENTS 1 LETTER FROM THE DIRECTOR 1 2 THE WEATHERHEAD EAST ASIAN INSTITUTE AT COLUMBIA UNIVERSITY 2 3 THE RESEARCH COMMUNITY 3 4 PUBLICATIONS 26 5 RESEARCH CENTERS AT THE WEATHERHEAD EAST ASIAN INSTITUTE AND AFFILIATED COLUMBIA PROGRAMS 30 6 PUBLIC PROGRAMMING 34 7 GRADUATE AND POSTDOCTORAL STUDIES 39 8 STUDENTS 43 9 ASIA FOR EDUCATORS PROGRAM 47 10 AdMINISTRATIVE STAFF OF THE WEATHERHEAD EAST ASIAN INSTITUTE 50 11 FUNDING SOURCES 51 12 COLUMBIA UNIVERSITY MAP: MORNINGSIDE CAMPUS & ENVIRONS 52 1 LETTER FROM THE DIRECTOR Over the past year, the Weatherhead East Asian Institute’s leading position in regional studies was amply reaffirmed. A fitting finale to our 60th anniversary celebrations was the June 13, 2010, symposium in Taipei, “Taiwan in the Twenty-first Century: Politics, Economy and Society.” This symposium continued WEAI’s outreach programs in East Asia to local Columbia alumni and to all prior visiting scholars, professional fellows, or participants at WEAI. The first three symposia were held in Beijing, Tokyo, and Seoul during May and June of 2009, and planning is now under way for a May 2011 sym- posium to take place in Hong Kong. As with the earlier events, the Taipei symposium involved close cooperation with the Columbia Alumni Association. The local signifi- cance of the symposium was underscored by the keynote speaker, Vincent Siew, vice president of the Republic of China (Taiwan), and by the meeting on the following day of symposium panelists and speakers with ROC President Ma Ying-jeou. -
President's Column
AAAS Publication for the members N of the Americanewsletter Astronomical Society September/October 2010, Issue 154 CONTENTS President's Column Debra Meloy Elmegreen, [email protected] 2 Congratulations to all of us in the astronomical community on the completion of the Decadal From the Survey! Two years after the National Research Council organized the Astro2010 Committee to begin its arduous process, the report “New Worlds, New Horizons in Astronomy and Astrophysics” Executive Office is complete. In fact, as I write this article the public roll-out is underway at the Keck Center of the National Academies in Washington, DC. This was truly a community effort, and we should all be proud of it and feel ownership of it. The federal funding agencies and Congress widely view the 3 astronomy decadal process as a model for other disciplines to emulate, and it is extremely important for us to embrace it. Editor, The Astrophysical We are embarking on a period of unprecedented opportunities for astronomical research, thanks to great advances in technology, theory, and observations, and the report presents an exciting Journal Letters and balanced set of science-driven priorities within the framework of realistic budget scenarios. The Astro2010 committee comprised 23 astronomers, selected by the National Academies based on community solicitation of suggested names, who were assisted by panels on different science 4 disciplines, space- and ground-based activities, and study groups on the astronomical infrastructure; these subcommittees had a membership of nearly 200 astronomers from the US astronomical Journals Update community. The Survey report and the panel reports are the culmination of a careful and deliberate consideration of science goals, projects and missions and on the whole astronomical enterprise, based in part on the distillation of over 450 community-submitted white papers, over 100 proposals for 6 research activities, briefings from federal agencies, and 17 Town Halls, along with other federal and international reports. -
Science & ROGER PENROSE
Science & ROGER PENROSE Live Webinar - hosted by the Center for Consciousness Studies August 3 – 6, 2021 9:00 am – 12:30 pm (MST-Arizona) each day 4 Online Live Sessions DAY 1 Tuesday August 3, 2021 9:00 am to 12:30 pm MST-Arizona Overview / Black Holes SIR ROGER PENROSE (Nobel Laureate) Oxford University, UK Tuesday August 3, 2021 9:00 am – 10:30 am MST-Arizona Roger Penrose was born, August 8, 1931 in Colchester Essex UK. He earned a 1st class mathematics degree at University College London; a PhD at Cambridge UK, and became assistant lecturer, Bedford College London, Research Fellow St John’s College, Cambridge (now Honorary Fellow), a post-doc at King’s College London, NATO Fellow at Princeton, Syracuse, and Cornell Universities, USA. He also served a 1-year appointment at University of Texas, became a Reader then full Professor at Birkbeck College, London, and Rouse Ball Professor of Mathematics, Oxford University (during which he served several 1/2-year periods as Mathematics Professor at Rice University, Houston, Texas). He is now Emeritus Rouse Ball Professor, Fellow, Wadham College, Oxford (now Emeritus Fellow). He has received many awards and honorary degrees, including knighthood, Fellow of the Royal Society and of the US National Academy of Sciences, the De Morgan Medal of London Mathematical Society, the Copley Medal of the Royal Society, the Wolf Prize in mathematics (shared with Stephen Hawking), the Pomeranchuk Prize (Moscow), and one half of the 2020 Nobel Prize in Physics, the other half shared by Reinhard Genzel and Andrea Ghez. -
2009 NIH Director's Transformative Research Award Reviewers
2009 NIH Director’s Transformative Research Award Reviewers Editorial Board Members Chairs David Botstein Keith Robert Yamamoto Princeton University University of California, San Francisco Members John T. Cacioppo Myron P. Gutmann University of Chicago Inter-University Consortium for Political and Social Research Aravinda Chakravarti Johns Hopkins School of Medicine Nola M. Hylton-Watson University of California, San Francisco Garret A. Fitzgerald Cecil B. Pickett University of Pennsylvania Biogen Idec Alfred G. Gilman Susan S. Taylor University of Texas Southwestern Medical University of California at San Diego Center Michael J. Welsh University of Iowa Mail Reviewers Craig Kendall Abbey Margaret Ashcroft University of California, Santa Barbara Division of Medicine Samuel Achilefu Richard Herbert Aster School of Medicine Blood Research Institute Manuel Ares Arleen D. Auerbach University of California Rockefeller University Bruce A. Armitage J. Thomas August Carnegie Mellon University Johns Hopkins University Mark A. Arnold Kevin A. Ault University of Iowa Emory University School of Medicine David C. Aron Jennifer Bates Averill Case Western Reserve University University of New Mexico 1 Mary Helen Barcellos-Hoff Leslie A. Bruggeman New York University School of Medicine Case Western Reserve University David P. Bartel Peter Burkhard New Cambrige Center University of Connecticut Ralf Bartenschlager Alma L. Burlingame University of Heidelberg University of California, San Francisco Rashid Bashir Frederic D. Bushman University of Illinois at Urbana – Champaign University of Pennsylvania Carl A. Batt Robert William Caldwell Cornell University Medical College of Georgia Mark T. Bedford Phil Gordon Campbell Research Division Carnegie Mellon University Kevin D. Belfield Joseph Nicholas Cappella University of Central Florida University of Pennsylvania Andrew Steven Belmont William A. -
Professor Roger Blandford Stanford University, USA
2020 Jacques Solvay International Chair in Physics Professor Roger Blandford Stanford University, USA 5 ONLINE LECTURES VIA ZOOM Thursday 11 March 2021 at 5:30 PM Black Holes: Nature or Nurture?: The Role of Rotation in Powering Cosmic Sources Black holes power many of the most powerful sources in the universe through releasing the gravitational energy of accreting gas and by donating their rotational energy using electromagnetic feld. The interpre- tation of recent, remarkable images made by the Event Horizon Telescope of M87 will be discussed in the context of both modes. It will be proposed that the rotational mode dominates in sources like M87 so that the black hole spin drives away the accreting gas as a powerful hydromagnetic wind that collimates a pair of relativistic jets. Zoom Link: https://zoom.us/j/92256891111?pwd=NmROZHRBdStvbnUxR1BWb1A1ZlIydz09 Monday 15 March 2021 at 5:30 PM Cosmic Blowtorches: Relativistic Jets from Stars and Galaxies Powerful relativistic jets are made by black holes and neutron stars. They are prodigious emitters from the lowest radio frequencies to the highest energy gamma-rays. They may also create high energy cosmic rays and neutrinos. They are remarkably persistent as they escape from collapsing stars, active galaxies and merging neutron stars. It will be argued that their collimation, resilience and emission is generically due to the tensile action of electromagnetic feld. Zoom Link: https://zoom.us/j/93200154324?pwd=R2xqOEpKNVYwbU5xU1Z5bm1WL3djdz09 www.solvayinstitutes.be à 2020 Jacques Solvay International Chair in Physics Friday 19 March 2021 at 4:00 PM Fast Radio Bursts: ElectroMagnetic Pulses from Cosmologically Distant Neutron Stars with Hundred GigaTesla Magnetic Field? For over a decade, radio astronomers have been observing millisecond pulses of intense radio emission. -
Molecular and Cellular Biology Volume 8 May 1988 Number 5
MOLECULAR AND CELLULAR BIOLOGY VOLUME 8 MAY 1988 NUMBER 5 Aaron J. Shatkin, Editor in Chief(1990) Randy W. Schekman, Editor Joan A. Steitz, Editor (1990) Center for Advanced (1992) Yale University Biotechnology and Medicine University of California New Haven, Conn. Piscataway, N.J. Berkeley Robert Tjian, Editor (1991) David J. L. Luck, Editor (1992) Louis Siminovitch, Editor (1990) University of California Rockefeller University Mount Sinai Hospital Berkeley New York, N.Y. Toronto, Canada Harold E. Varmus, Editor (1989) Steven L. McKnight, Editor (1992) University of California Carnegie Institution of Washington San Francisco Baltimore, Md. EDITORIAL BOARD Frederick W. Alt (1990) Michael Green (1988) Douglas Lowy (1990) Matthew P. Scott (1989) Susan Berget (1990) Jack F. Greenblatt (1988) Paul T. Magee (1988) Fred Sherman (1988) Arnold J. Berk (1988) Leonard P. Guarente (1988) James Manley (1989) Arthur Skoultchi (1988) Alan Bernstein (1990) Christine Guthrie (1989) Janet E. Mertz (1990) Barbara Sollner-Webb (1989) Barbara K. Birshtein (1990) James E. Haber (1990) Robert L. Metzenberg (1988) Frank Solomon (1988) J. Michael Bishop (1990) Hidesaburo Hanafusa (1989) Robert K. Mortimer (1988) Karen Sprague (1989) Michael R. Botchan (1990) Leland D. Hartwell (1990) Bernardo Nadal-Ginard (1990) Pamela Stanley (1988) David Botstein (1990) Ari Helenius (1990) Paul Neiman (1989) Nat Sternberg (1989) Bruce P. Brandhorst (1990) Ira Herskowitz (1990) Joseph R. Nevins (1990) Bruce Stiliman (1988) James R. Broach (1988) James B. Hicks (1989) Carol Newlon (1988) Kevin Struhl (1989) Joan Brugge (1988) Alan Hinnebusch (1988) Mary Ann Osley (1990) Bill Sugden (1988) Mario R. Capecchi (1990) Michael J. Holland (1990) Brad Ozanne (1989) Lawrence H. -
Meeting Program
A A S MEETING PROGRAM 211TH MEETING OF THE AMERICAN ASTRONOMICAL SOCIETY WITH THE HIGH ENERGY ASTROPHYSICS DIVISION (HEAD) AND THE HISTORICAL ASTRONOMY DIVISION (HAD) 7-11 JANUARY 2008 AUSTIN, TX All scientific session will be held at the: Austin Convention Center COUNCIL .......................... 2 500 East Cesar Chavez St. Austin, TX 78701 EXHIBITS ........................... 4 FURTHER IN GRATITUDE INFORMATION ............... 6 AAS Paper Sorters SCHEDULE ....................... 7 Rachel Akeson, David Bartlett, Elizabeth Barton, SUNDAY ........................17 Joan Centrella, Jun Cui, Susana Deustua, Tapasi Ghosh, Jennifer Grier, Joe Hahn, Hugh Harris, MONDAY .......................21 Chryssa Kouveliotou, John Martin, Kevin Marvel, Kristen Menou, Brian Patten, Robert Quimby, Chris Springob, Joe Tenn, Dirk Terrell, Dave TUESDAY .......................25 Thompson, Liese van Zee, and Amy Winebarger WEDNESDAY ................77 We would like to thank the THURSDAY ................. 143 following sponsors: FRIDAY ......................... 203 Elsevier Northrop Grumman SATURDAY .................. 241 Lockheed Martin The TABASGO Foundation AUTHOR INDEX ........ 242 AAS COUNCIL J. Craig Wheeler Univ. of Texas President (6/2006-6/2008) John P. Huchra Harvard-Smithsonian, President-Elect CfA (6/2007-6/2008) Paul Vanden Bout NRAO Vice-President (6/2005-6/2008) Robert W. O’Connell Univ. of Virginia Vice-President (6/2006-6/2009) Lee W. Hartman Univ. of Michigan Vice-President (6/2007-6/2010) John Graham CIW Secretary (6/2004-6/2010) OFFICERS Hervey (Peter) STScI Treasurer Stockman (6/2005-6/2008) Timothy F. Slater Univ. of Arizona Education Officer (6/2006-6/2009) Mike A’Hearn Univ. of Maryland Pub. Board Chair (6/2005-6/2008) Kevin Marvel AAS Executive Officer (6/2006-Present) Gary J. Ferland Univ. of Kentucky (6/2007-6/2008) Suzanne Hawley Univ. -
David Botstein 2015 Book.Pdf
Princeton University HONORS FACULTY MEMBERS RECEIVING EMERITUS STATUS May 2015 The biographical sketches were written by colleagues in the departments of those honored. Copyright © 2015 by The Trustees of Princeton University 550275 Contents Faculty Members Receiving Emeritus Status 2015 Steven L. Bernasek .......................3 David Botstein...........................6 Erhan Çinlar ............................8 Caryl Emerson.......................... 11 Christodoulos A. Floudas ................. 15 James L. Gould ......................... 17 Edward John Groth III ...................20 Philip John Holmes ......................23 Paul R. Krugman .......................27 Bede Liu .............................. 31 Alan Eugene Mann ......................33 Joyce Carol Oates .......................36 Clarence Ernest Schutt ...................39 Lee Merrill Silver .......................41 Thomas James Trussell ...................43 Sigurd Wagner .........................46 { 1 } { 2 } David Botstein avid Botstein was educated at Harvard (A.B. 1963) and the D University of Michigan (Ph.D. 1967). He joined the faculty of the Massachusetts Institute of Technology, rising through the ranks from instructor to professor of genetics. In 1987, he moved to Genentech, Inc. as vice president–science, and, in 1990, he joined Stanford University’s School of Medicine, where he was chairman of the Department of Genetics. In July, 2003 he became director of the Lewis-Sigler Institute for Integrative Genomics and the Anthony B. Evnin ’62 Professor of Genomics at Princeton University. David’s research has centered on genetics, especially the use of genetic methods to understand biological functions. His early work in bacterial genetics contributed to the discovery of transposable elements in bacteria and an understanding of their physical structures and genetic properties. In the early 1970s, he turned to budding yeast (Saccharomyces cerevisiae) and devised novel genetic methods to study the functions of the actin and tubulin cytoskeletons.