University of Massachusetts Medical School eScholarship@UMMS Open Access Articles Open Access Publications by UMMS Authors 2017-09-01 Tobacco use disorder and treatment: new challenges and opportunities Douglas Ziedonis University of California - San Diego Et al. Let us know how access to this document benefits ou.y Follow this and additional works at: https://escholarship.umassmed.edu/oapubs Part of the Behavior and Behavior Mechanisms Commons, Neuroscience and Neurobiology Commons, and the Substance Abuse and Addiction Commons Repository Citation Ziedonis D, Das S, Larkin C. (2017). Tobacco use disorder and treatment: new challenges and opportunities. Open Access Articles. Retrieved from https://escholarship.umassmed.edu/oapubs/3255 Creative Commons License This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License. This material is brought to you by eScholarship@UMMS. It has been accepted for inclusion in Open Access Articles by an authorized administrator of eScholarship@UMMS. For more information, please contact
[email protected]. Clinical research Tobacco use disorder and treatment: new challenges and opportunities Douglas Ziedonis, MD, MPH; Smita Das, MD, PhD, MPH; Celine Larkin, PhD Introduction obacco use is the cause of over 5 million deaths perT year globally,1 over twice as many deaths due to al- cohol and illicit drugs combined. If current consump- tion rates continue, tobacco is projected to kill 1 billion people this century, with the majority of deaths occur- ring in low- and middle-income countries,2 although there is good evidence for the effectiveness both of pol- Tobacco use remains a global problem, and options for consumers have increased with the development and mar- keting of e-cigarettes and other new nicotine and tobacco products, such as “heat-not-burn” tobacco and dissolv- able tobacco.