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Raka Mustaphi Mitra RAKA MUSTAPHI MITRA Department of Biology Ph: (507) 222-4120 Carleton College Fax: (507) 222-5757 One North College Street http://apps.carleton.edu/people/rmitra/ Northfield, MN 55057 U.S.A. POSITION 2008-Present Assistant Professor, Biology Department, Carleton College EDUCATION 1996-2003 Stanford University, Stanford, CA Ph.D., Biological Sciences 1992-1996 Massachusetts Institute of Technology, Cambridge, MA S.B., Biology. G.P.A. 4.8 / 5.0 RESEARCH EXPERIENCE 2004-2008 Postdoctoral Fellow, University of Minnesota (Research Advisor: Dr. Jane Glazebrook) Studies of the plant defense response to pathogens of leaves and roots. 2003-2004 Postdoctoral Researcher, Stanford University (Research Advisor: Dr. Sharon Long) Studies of plant symbiotic gene expression and identification of the Medicago truncatula DMI3 gene using transcript-based gene cloning. 1996-2003 Graduate Research, Stanford University (Research Advisor: Dr. Sharon Long) Studies of early plant gene expression and calcium signaling in the Rhizobium-legume symbiosis. 1995-1996 Research Assistant, Massachusetts Institute of Technology (Research Advisor: Dr. Harvey Lodish) Investigation of the role of Rab4 and Rab5 in recycling of the Glut4 glucose transporter in adipocytes. 1994-1995 Research Assistant, Massachusetts Institute of Technology (Research Advisor: Dr. Jonathan King) Studies of the effects of mutant scaffolding proteins on the assembly of bacteriophage P22. 1993-1994 Research Assistant, University of Minnesota (Research Advisor: Dr. Glenn Furnier) RAPD analyses of genetic variation of the Butternut canker fungus Sirococcus clavigignenti-juglandacearum. 1991-1992 Research Assistant, University of Minnesota (Research Advisor: Dr. Glenn Furnier) Isozyme analyses of Eurasian watermilfoil (Myriophyllum spicatum L.) 8/25/14 R. Mitra TEACHING EXPERIENCE Winter 2009 - present Supervisor Undergraduate Biology Research, Carleton College Responsibilities include designing and supervising undergraduate research projects to examine the role of pathogenic effectors of the bacterial pathogen of plants, Ralstonia solanacearum. Total number of students supervised to date: 18. Spring 2009 - present Course Instructor, Carleton College Course: Cell Biology. A mid-level course that examines of the structures and processes that underlie life in prokaryotic and eukaryotic cells. Includes two weekly lab components in which students perform original research investigating the cell biology of plant microbe interactions. Winter 2009 - present Course Instructor, Carleton College Course: Introductory Biology; Energy Flow. An introductory course designed for both majors and non-majors. Explores the flow of energy in biological systems from molecules to ecosystems. Includes a weekly lab component. Fall 2008 – present Course Instructor, Carleton College Course: Microbial Pathology. An upper level course, for juniors and seniors. Goals include teaching students how to critically read and understand primary research papers in the field of microbial pathology. Students learn about the scientific publication process, pathogenesis proteins, biological processes and scientific techniques used to study microbial pathogenesis. Winter 2009 –present Course Advisor, Carleton College Course: Biology Integrative Exercise. A senior capstone project where students investigate a particular biological question. Fall 2006 Course Instructor, University of Minnesota Course: Genetically Modified Plants, the Science and the Controversy Collaborated with two other postdoctoral instructors to design and teach a course for undergraduate and graduate students. Responsibilities include presenting lectures, teaching a lab, facilitating discussion, grading papers and composing exams. Fall 2005, 2006 Guest Lecturer, University of Minnesota Course: Genetics Presented lectures on various topics including Genomics and DNA replication. 2005-Present Supervisor Undergraduate Directed Research Projects, University of Minnesota Responsibilities include designing undergraduate research projects to identify plant genes important for pathogen defense, and advising several undergraduate students. Winter 1999 Teaching Assistant, Stanford University Course: Cell Biology: Molecular Organization Responsibilities included leading a weekly one-hour discussion section, conducting problem solving demonstrations, grading and composing problems for exams, and tutoring individual students. page 2 R. Mitra Spring 1999 Teaching Assistant, Stanford University Course: Cell Biology: Cellular Dynamics Responsibilities included leading a two-hour paper discussion section every other week, meeting with students individually to discuss presentations and grading exams. Winter 1998 Teaching Assistant, Stanford University Course: Biochemistry, Molecular Biology and Cell Biology Responsibilities included leading two one-hour discussion sections per week, preparing handouts, grading exams and tutoring individual students. GRANTS, AWARDS AND FELLOWSHIPS National Science Foundation Biology Division of Integrative Organismal Systems “RUI: The role of Ralstonia solanacearum effector protein Rsp1281 in bacterial wilt disease.” Howard Hughes Medical Institute Predoctoral Fellowship Frances Lou Kallman Award for Graduate Study in Biological Sciences, Stanford University National Institutes of Health Postdoctoral Fellowship Curricular Development Grant, Carleton College Howard Hughes Medical Institute Curricular Project Grant, Carleton College Faculty Development Grant, Carleton College Mellon Fellowship, Carleton College Class of ’49 Fellowship, Carleton College American Society of Plant Biology Travel Award American Society of Cell Biology Faculty Travel Award American Society of Cell Biology Childcare Award PUBLICATIONS Jacobs JM, Milling A, Mitra RM, Hogan CS, Florent Ailloud F, Prior P, Allen C. Ralstonia solanacearum requires PopS, an ancient AvrE-family effector, for virulence and to overcome salicylic acid-mediated defenses during tomato pathogenesis. MBio. 2013 Nov 26;4(6). Wang L, Mitra RM, Hasselmann KD, Sato M, Lenarz-Wyatt L, Cohen JD, Katagiri F, Glazebrook J. The genetic network controlling the Arabidopsis transcriptional response to Pseudomonas syringae pv. maculicola: roles of major regulators and the phytotoxin coronatine. Mol Plant Microbe Interact. 2008 Nov;21(11):1408-20. Middleton P, Jakab J, Penmetsa V, Starker C, Doll J, Kalo P, Prabhu R, Marsh J, Mitra RM, Kerestz A, Dudas B, VandenBosch K, Long SR, Cook D, Kiss G, Oldroyd GED. An ERF transcription factor in Medicago truncatula that is essential for Nod factor signal transduction. Plant Cell. 2007 Apr; 19(4):1221- 34. Marsh JF, Rakocevic A, Mitra RM, Brocard L, Sun J, Eschstruth A, Long SR, Schultze M, Ratet P, Oldroyd GED. Medicago truncatula NIN is essential for nodule organogenesis induced by autoactive calcium/calmodulin dependent protein kinase. Plant Physiol. 2007 May; 144(1) 324-335. Sato M, Mitra RM, Coller J, Wang D, Spivey NW, Dewdney J, Denoux C, Glazebrook J., Katagiri F. A high performance, small-scale microarray for expression profiling of many samples in Arabidopsis- pathogen studies. Plant J. 2007 Feb; 49 (3) 565-567. Starker CG, Parra-Colmenares AL, Smith L, Mitra RM, Long SR. Nitrogen fixation mutants of Medicago truncatula fail to support plant and bacterial symbiotic gene expression. Plant Physiol. 2006 Feb; 140 (2): 671-680. page 3 R. Mitra Kaló P, Gleason C, Edwards A, Marsh J, Mitra RM, Hirsch S, Jakab J, Sims S, Long SR, Rogers J, Kiss GB, Downie JA, Oldroyd GE. Nodulation signaling in legumes requires NSP2, a member of the GRAS family of transcriptional regulators. Science. 2005 Jun 17;308(5729):1786-1789. Mitra RM, Shaw SL, Long SR. Six nonnodulating plant mutants defective for Nod factor-induced transcriptional changes associated with the legume-rhizobia symbiosis. Proc. Natl. Acad. Sci. U.S.A. 2004 Jul 6;101(27):10217-10222. Mitra RM, Gleason CA, Edwards A, Hadfield J, Downie JA, Oldroyd GE, Long SR. A Ca2+/calmodulin- dependent protein kinase required for symbiotic nodule development: Gene identification by transcript- based cloning. Proc. Natl. Acad. Sci. U.S.A. 2004 Mar 30;101(13):4701-4705. Mitra RM, Long SR. Plant and bacterial symbiotic mutants define three transcriptionally distinct stages in the development of the Medicago truncatula/Sinorhizobium meliloti symbiosis. Plant Physiol. 2004 Feb; 134 (2): 595-604. Engstrom EM, Ehrhardt DW, Mitra RM, Long SR. Pharmacological analysis of Nod factor-induced calcium spiking in Medicago truncatula. Plant Physiol. 2002 Apr; 128(4):1390-1401. Oldroyd GE, Mitra RM, Wais RJ, Long SR. Evidence for structurally specific negative feedback in the Nod factor signal transduction pathway. Plant J. 2001 Oct; 28(2):191-199. Furnier GR, Stoltz AM, Mustaphi RM, Ostry ME. Genetic evidence that butternut canker was recently introduced into North America. Can. J. Bot. 1999 June; 77(6):783-785. Furnier GR, Mustaphi MM. Isozyme variation in Minnesota populations of Eurasian watermilfoil. Aquatic Bot. 1992 Oct; 43(3):305-309. MEETINGS August 2014 2014 American Phytopathological Society, Canadian Phytopathological Society Joint Meeting December 2013 American Society of Cell Biology 2013 Annual Meeting July 2012 Plant Biology 2012 August 2011 Plant Biology 2011 July 2009 14th International Congress on Molecular Plant-Microbe Interactions November 2008 Council on Undergraduate Research Institute: Beginning a Research Program in the Natural Sciences at Predominantly Undergraduate Institutions. November 2008 NSF iPlant collaborative
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