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CURRICULUM VITAE Jeffery M. Coller, Ph.D. DATE: October 2, 2017

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CURRICULUM VITAE Jeffery M. Coller, Ph.D. DATE: October 2, 2017 CURRICULUM VITAE Jeffery M. Coller, Ph.D. DATE: October 2, 2017 PROFESSIONAL ADDRESS HOME ADDRESS Center for RNA Science and Therapeutics 19683 Chagrin Blvd. Case Western Reserve University Shaker Heights, OH 44122 School of Medicine Tel. (216) 543-3258 Wood Bldg. W113 10900 Euclid Ave. ORCID - 0000-0001-5662-8110 Cleveland OH 44106-4960 h-index = 20 (as of 2016). Tel. (216) 368-0299 Fax (216) 368-2010 e-mail: [email protected] EDUCATION Post-doctoral Howard Hughes Medical Institute & The University of Arizona Department of Molecular & Cellular Biology, 2001-2005 Ph.D. The University of Wisconsin-Madison Cellular and Molecular Biology, 1994-2000 B.S. (Hons) The University of Michigan Biochemistry, 1990-1994 Stockholms Universitet, Sweden Visiting researcher, Department of Molecular Biology, 1993 PROFESSIONAL APPOINTMENTS Assistant Professor, Case Western Reserve University, Cleveland OH -July 1, 2005 - June 30, 2013 Associate Professor with Tenure, Case Western Reserve University, Cleveland, OH - July 1, 2013 - June 30, 2017 Associate Director, Center for RNA Molecular Biology, Case Western Reserve University, Cleveland, OH - July 1, 2014 - June 30, 2016 Director, Center for RNA Science and Therapeutics, Case Western Reserve University, Cleveland, OH - July 1, 2016 - present Full Member - Molecular Oncology Program, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH - October 1, 2016 - present Full Professor, Case Western Reserve University, Cleveland, OH - July 1, 2017 PROFESSIONAL SOCIETY MEMBERSHIPS The RNA Society, 2005-present Faculty of 1000, 2005-present 1 PROFESSIONAL SERVICE Board of Directors, The International RNA Society 2018-2019 Editorial Board - PLoS Biology, January 1, 2017 - present Young Scientist Foundation Mentor, December 1, 2016 - present Harrington Discovery Institute Executive Committee, September 1, 2016 - present Organizer of the 2016 International FASEB conference on mRNA turnover - Lisbon Portugal, July 10-15, 2016 Scientific Advisor for Houston Methodist Research Institute - RNA Therapeutic Core - January 1, 2016 - present Consultant for PhaseRX Therapeutics, Seattle WA - November 1, 2015 - January 1, 2018 Consultant for Proteostasis Therapeutics, Boston MA - March 1, 2015 - 2016 Grant Panels National Institutes of Health Study Section MGA - permanent member - 2014-2018 W.M. Keck Foundation - ad hoc - 2016 National Institutes of Health Special Emphasis Study Section - ad hoc - 2013 National Science Foundation Genes and Genomes Division - ad hoc - 2013 National Institutes of Health Study Section MGA - ad hoc - 2011 National Institutes of Health Special Emphasis Study Section - ad hoc - 2011 Biotechnology and Biological Science Research Council - UK - ad hoc - 2010 Israeli Science Foundation - ad hoc - 2010 Volkswagen Foundation - Germany - ad hoc - 2010 Agence Nationale De La Recherche - France - ad hoc - 2010 National Science Foundation Genes and Genomes Division - ad hoc - 2009 Medical Research Council - UK - ad hoc - 2009 Wellcome Trust - UK - ad hoc - 2006, 2007, 2008, 2009 National Science Foundation MCB Division - ad hoc - 2008, 2009, 2011 Peer reviewer Nature The Journal of Histological Chemistry Science EMBO Reports Cell Journal of Biological Chemistry eLIFE Nucleic Acids Research Nature Structural and Molecular Biology Biology of the Cell Molecular Cell Biochemical and Biophysical Research Cell Reports Communications Structure PLOS One Genes and Development FEBS Letters RNA Biomolecular Concepts PLOS Biology Genetics Molecular Biology of the Cell WIREs RNA Nature Reviews in Molecular Biology Genome Biology Molecular and Cellular Biology Editorial Guest Editor PLoS Genetic June 2014 2 UNIVERSITY SERVICE 2005- 2008 Organizer of RNA Center Student Seminar Series. 2006- present Undergraduate Academic Advisor for the Department of Biochemistry 2007-2015 Radiation Safety Committee (RSC) 2009-present Biomedical Sciences Training Program Graduate Student Admission Committee 2010-2012 Scientific advisory board for the Genome and Transcriptome Sequencing Core at CWRU 2012-2013 Ad hoc committee to evaluate the CWRU SOM Research Committee 2016-present Committee on Biomedical Research (CBR) - Biomedical Workforce Council 2016-present Council for Basic Science Chairs 2017-2018 Vice Chair, Council for Basic Science Chairs 2017-2018 Ad hoc committee on the CWRU Intellectual Property Policy. 2018-present Member of the MSTP Advisory Board TEACHING ACTIVITIES All courses have been taught at Case Western Reserve University Biochemistry 519 Molecular Biology of RNA. 8 contact hours (2006-2011) Biochemistry 599 RNA Structure and Function. 8 contact hours (2007-2012) WR2 Medical Student Core Curriculum, Medium Size Group, gene expression unit. 10 contact hours (2007-2012). Cell Biology 455 Correlated Curriculum in Cell and Molecular Biology. 8 contact hours (2007- present) Molecular Biology 488 Yeast Genetics and Molecular Biology, 45 contact hours (2006-present) Biochemistry 354 Biochemistry and Biology of RNA. 45 contact hours (2014-present). MENTORING ACTIVITIES MEDICAL FELLOWS Darwin Jeyaraj, M.D. (2011-2012) 3 Gavin Hanson, M.D. Ph.D. (2016 - present) POST-DOCOTORAL FELLOWS Dr. Trinh Tat (2015 - 2016): Trained in the laboratory of Dr. Tim Nilsen (CWRU) Dr. Sophie Martin (2013 - present): Trained in the laboratory of Dr. Jamel Tazi (Institut de Génétique Moléculaire de Montpellier) DOCTORAL STUDENTS Wenqian Hu, Ph.D. (2005-2010) Current position (2015- present): Assistant Professor, Mayo Clinic, Rochester MN. Previous position (2010-2015): Post-doctoral fellow at the Whitehead Institute at MIT in the lab of Dr. Harvey Lodish Distinctions under my mentorship •Recipient of the 2010 CWRU Doctoral Excellence Award •First Prize at the 2010 Case Research Showcase •First Prize at the 2009 Case Research Showcase •Recipient of the 2009 Cleveland Clinic Award at the Biomedical Graduate Student Symposium •Awarded "Best Oral Presentation" at the 10th annual Rustbelt RNA Meeting 2009 •Recipient of the Marcus Singer Award at the Biomedical Graduate Student Symposium, May 9th, 2008 •Recipient of the American Heart Association Pre-doctoral Fellowship, 2007-2009 Thomas J. Sweet, Ph.D. (2006-2011) Current position: Research Scientist in Center for RNA Science and Therapeutics, CWRU Distinctions under my mentorship •Recipient of the Marcus Singer Award at the 2009 Biomedical Graduate Student Symposium •Appointed to Cellular and Molecular Biology Training Grant, 2006 - 2008 Sarah J. Geisler, Ph.D. (2007- 2012) Current position: Scientific Editor, Cell Distinctions under my mentorship •Recipient of the 2012 CWRU Doctoral Excellence Award •Recipient of the Vance Lemmon Award, presented at the 2009 Biomedical Graduate Student Symposium •Appointed to Cellular and Molecular Biology Training Grant, 2008 - 2010 •Recipient of the Vance Lemmon Award, presented at the 2008 Biomedical Graduate Student Symposium Vlad Presnyak, Ph.D. (2009 - 2015) Current position: Moderna Therapeutics, Cambridge Massachusetts. Distinctions under my mentorship •Appointed to Cellular and Molecular Biology Training Grant, 2011 - 2012 4 Ying-Hsin Chen (2011 - present) Distinctions under my mentorship •Finalist for the Paul Berg Scholarship, Department of Biochemistry 2016 UNDERGRADUATE RESEARCHERS Christine Petzold, Ph.D. (2006-2010) Current position: 23 and Me, San Francisco, CA Distinctions under my mentorship •Dean’s High Honors: 2006-2007, Spring 2008, Spring 2009 •Mortar Board National College Senior Honor Society Spring 2008- 2010 •CWRU Women’s Varsity Swimming Team Member 2006- Present, Co-Captain 2008-2009 •Award the National Science Foundation Pre-doctoral Fellowship 2012 Linda Saju (2010 - 2013) William Hannon (2016 - present) Shannon Bailey (2016 - present) PREP SCHOLARS (Postbaccalaureate Research Education Program) Ashanti Matlock (2011-2012) Tiffany Rolle (2013- 2014) HIGH SCHOOL STUDENTS (Gilmour Academy Catalyst Program) Courtney Rulison Nickolas Celeste Alli Catelaz Laurn Flocken Adam Miller Allie Kasuboski Caitlin Finelli Elizabeth McEriean Monica Flocken Nick Pilla Reem Azem Brooke Boyer Natalie Doe Lexi Antunez Talla Azem RESEARCH SUPPORT Current “Graduate Training in Cell and Molecular Biology” Agency: National Institutes of Health Type: Training Grant Period: June 1st, 2017 to May 30th, 2022 PI: J. Coller “Understanding the interconnection between mRNA turnover and mRNA translation” Agency: National Institutes of Health Type: RO1 Research Project, Federal Support Period: March 1, 2013 to June 30, 2021 PI: J. Coller “Determining the influence of codon optimality on mRNA translation and decay” Agency: National Institutes of Health Type: RO1 Research Project, Federal Support Period: July 1, 2017 to June 30, 2021 5 PI: J. Coller Zafgen Therapeutics, Boston MA Type: Sponsored research agreement Period: November 1, 2017-October 30, 2018 PI: J. Coller Tevard Biosciences, Boston MA Type: Sponsored research agreement Period: November 1, 2017-October 30, 2018 PI: J. Coller Completed Proteostasis Therapeutics, Boston MA Type: Sponsored research agreement Period: April 1, 2015 - March 30, 2016 PI: J. Coller “Investigating the process of removing mRNAs from translation” Agency: National Institutes of Health Type: ARRA-RO1 supplement Research Project, Federal Support Period: August 10, 2009 to July 31, 2012 PI: J. Coller “Transferring research from a model system to uncover the network that regulates long-distance signaling in potato” (25% effort) Agency: National Science Foundation Type: Plant Genome Research Project
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