physical examination and history, basic blood tests, how to take and read COMPARATIVE an x-ray, how to identify infecting microbes, and histopathology. How- to demonstrations. Chair: Linda C. Cork 3 units, Spr (Beckwith) Professor: Linda C. Cork Associate Professor: Sherril Green, Shaul Hestrin, Glen Otto, Ravi COMPMED 99N. Mechanisms of Disease—Stanford Introductory Tolwani Seminar. Preference to freshmen. The basic mechanisms of disease. An Assistant Professors: Catherine Beckwith, Donna Bouley, Paul overview of disease outbreaks caused by infectious pathogens, chronic Buckmaster, Corinna Darian-Smith, Manuel Garcia exposure to toxins, and other transmissible diseases. Goal is to develop an understanding of disease through examination of epidemiology, symp- Department Offices: Edwards Building, Room R321 toms, , diagnostic techniques, possible treatments, and preven- Mail Code: 94305-5342 tive measures. Students form groups for their final presentation in poster Department Phone: (650) 498-5080 format dealing with an investigation into some mystery disease outbreak. Web site: http://www.med.stanford.edu/school/CompMed/ Prerequisite: freshman , cell biology, or high school AP biology. Courses given in Comparative Medicine have the subject code 3 units, Spr (Bouley) COMPMED. For a complete list of subject codes, see Appendix B. COMPMED 107/207. Comparative Neuroanatomy—(Graduate stu- The Department of Comparative Medicine is a clinical department dents register for 207.) The structure and function of vertebrate brains. and does not offer degrees, but its faculty offer courses and participate Focus is on laboratory animals commonly used in neuroscience research, in teaching in other departments at the undergraduate and graduate lev- and comparisons made with the human brain. Advantages and limitations el. Faculty members, most of whom are specialists in some veterinary of species chosen for neurobiological and biomedical research. Introduc- medical specialty, also accept students to participate in ongoing research tion to neuroanatomical methods and possible mechanisms of brain projects within the department and assist students with special research evolution. Discussion section for graduate students. Undergraduates projects. may take discussion section with consent of instructor. Prerequisite: The discipline of Comparative Medicine utilizes the differences and course in basic biology. similarities among species to understand basic biologic and disease 2-4 units, Aut (Buckmaster) mechanisms. Comparative Medicine incorporates the use of spontane- ous or induced disease models as one of several approaches to research. COMPMED 108/208. Animals Advancing Biomedical Technology— (Graduate students register for 208.) Open to graduate students and The research interests of faculty members are in neuroscience, infectious Comparative Medicine diseases, neuropathology, molecular genetics and anesthesiology. undergraduates in all degree programs; students enrolled in computer science and engineering programs or who are affiliated with the BioX COURSES program are especially encouraged to enroll. Lectures by faculty mem- bers in Comparative Medicine and invited speakers from the biomedical Course and lab instruction in the Department of Comparative Medi- industry. Goal is to introduce the role of animals in biomedical research. cine conforms to the “Policy on the Use of Vertebrate Animals in Teach- Possible topics include comparative and of species ing Activities,” the text of which is available at http://www.stanford.edu/ used in biotechnology and medical device research, selecting an animal dept/DoR/rph/8-2.html. model for a research project, the genetically engineered mouse, and preclinical, of medical devices intended for use in humans. COMPMED 81Q. Comparative Anatomy and Physiology of Mam- No background in animal biology required. mals—Stanford Introductory Seminar. Preference to sophomores. Com- 2 units, Aut (Green) parative approach to common mammals, laboratory, and domestic spe- cies. The unique adaptations of each species in terms of its morpholog- UNDERGRADUATE INDIVIDUAL WORK ical, anatomical, and behavioral characteristics. How these species COMPMED 198. Directed Reading—May be taken as a prelude to interact with humans and the historical relationships between humans research and may also involve participation in a lab or research group and these animal species. seminar and/or library research. 3 units, Win (Bouley) 1-3 units, any quarter

COMPMED 83Q. Horse Medicine—Stanford Introductory Seminar. COMPMED 199. Undergraduate Research—Individual research with Preference to sophomores. Overview of the most common equine diseases, department faculty. Prerequisite: consent of instructor. from colic to lameness. Equine anatomy and physiology. Equine infectious 1-3 units, by arrangement diseases, respiratory disorders, care of the newborn foal, a what’s-your- diagnosis problem series, and emergency first aid strategies. FOR GRADUATE STUDENTS 3 units, Win (Green) COMPMED 299. Directed Reading—Prerequisite: consent of instructor. COMPMED 85N. Animals in Biomedical Research—Stanford Intro- 1-18 units, any quarter ductory Seminar. Preference to freshmen. How and why animals are used COMPMED 399. Research—Opportunities are available in compara- in biomedical science and how animal models have advanced biomedical tive medicine and pathology, immuno-histochemistry, electron microsco- research. Documenting the humane care and treatment of laboratory py, molecular genetics, quantitative morphometry, neuroanatomy and animals in research and to the science of animal modeling for the purpose neurophysiology of the hippocampus, pathogenesis of intestinal infec- of studying human disease. Animal models provide an important tool to tions, immunopathology, biology of laboratory rodents, anesthesiology of study mechanisms of disease and develop new therapies. Examples of laboratory animals, gene therapy of animal models of neurodegenerative animal models in several medical disciplines. Discussions include genet- diseases, and development and characterization of transgenic animal ic engineering and other techniques used to develop animal models, and models. Enrollment limited to six. Prerequisite: consent of instructor. innovative approaches used to develop therapies for disease, including 1-18 units, any quarter gene therapy approach. 3 units, Aut (Green, Tolwani) This file has been excerpted from the Stanford Bulletin, 2002-03, COMPMED 86N. Methods of Diagnosis in — pages 643-644. Every effort has been made to insure accuracy; late Stanford Introductory Seminar. Preference to freshmen. For animal changes (after print publication of the bulletin) may have been made lovers from all backgrounds. The techniques and tools used by veterinar- here. Contact the editor of the Stanford Bulletin via email at ians to diagnose illnesses in their animal patients. Topics include the [email protected] with changes, corrections, updates, etc. 643 Excerpt from Stanford Bulletin, 2002-03