Curriculum Vitae MARLA B. FELLER

Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute Tel: (510) 643-1726 University of California, Berkeley Fax: (510) 643-6791 142 Life Sciences Addition Berkeley, CA 94720-3200 Email: [email protected]

EDUCATION: Ph. D., 1991 University of California, Berkeley, Physics Thesis: Studies of surfaces and liquid crystal interfaces by means of second-harmonic generation. Thesis Advisor: Professor Y. R. Shen

A. B., 1985 University of California, Berkeley, Physics

RESEARCH AND PROFESSIONAL EXPERIENCE: 2012 - present Professor, University of California, Berkeley 2013 - 2018 Head, Division of Neurobiology, Dept. of Molecular and Cell Biology, University of California, Berkeley 2011 Sabbatical at Institut Pasteur, Paris 2007 - 2012 Associate Professor, University of California, Berkeley 2005 - 2007 Associate Professor, University of California, San Diego 2000 - 2005 Assistant Professor, University of California, San Diego; Silvo Varon Professor of Neuroregeneration 1998 - 2000 Tenure-Track Investigator, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 1994 - 1997 Miller Postdoctoral Fellow, Department of Molecular and Cell Biology, University of California, Berkeley with Dr. Carla Shatz 1992 - 1994 Postdoctoral member of technical staff, Biological Computation Research Department, Bell Laboratories with Dr. David W. Tank 1993 Cold Spring Harbor Course is Visual System Development and Function 1992 MBL, Woods Hole, Summer Course, Neural Systems and Behavior

AWARDS AND HONORS: 2020 Distinguished Teaching Award, UC Berkeley 2019 Paul Licht Distinguished Professor in Biological Sciences 2019 Teaching Excellence Award, Department of Molecular and Cell Biology 2018 Distinguished Faculty Mentor Award, Graduate Assembly, UC Berkeley 2017 Fellow of the American Association for the Advancement of Science 2016 Pioneers in Neuroscience Award, University of Buffalo, SUNY, NY 2015 The Walter Massey Family Lectureship, Marine Biological Lab, Woods Hole, MA 2014 Brian Boycott Prize for career achievement in retinal neurobiology, awarded at the FASEB Summer Research Conference on Retinal Neurobiology and Visual Processing 2014 - 2015 Recipient of Peder Sather Grant 2014 Wayne E. Crill Lecturer, Dept. of Biophysics, University of Washington 2012 Recipient of France-Berkeley Fund Award 2011 Heller Distinguished Lecturer, Hebrew University 2011 Special Lecture, Society for Neuroscience Meeting 2011 Recipient of École des Neuroscience of Paris sabbatical award 2010 Anatomy and Neurobiology Graduate Student Society Sponsored Seminar Speaker at Dalhousie University 2010 Roger Brown Loucks Lectureship in the Neurophysiological Basis of Learning and Memory at University of Washington 2002 - 2005 McKnight Foundation Scholar Award 2002 - 2005 Whitehall Foundation Grant 2002 - 2004 March of Dimes Basil O'Connor Starter Award 2001 - 2004 Klingenstein Fellowship Award in Neurosciences 2000 - 2005 Silvio Varon Professorship in Neuroregeneration Faculty Chair 1994 - 1996 Miller Postdoctoral Fellowship, University of California 1992 Society of General Physiology Scholarship Recipient 1987 - 1991 AT&T Bell Laboratories Pre-doctoral Fellow 1985 - 1986 University of California Regents Fellow 1985 Physics Department Citation, University of California, Berkeley 1985 Phi Beta Kappa

PROFESSIONAL MEMBERSHIPS: 1988 - 2010 American Physical Society 1995 - present Association for Research in Vision and Ophthalmology 1995 - present Society for Neuroscience 1998 - present American Association for the Advancement of Science

TEACHING EXPERIENCE – University of California, Berkeley 2018 - present Undergraduate Lab Course – Neurobiology Lab (MCB160L) 2016 - present Undergraduate Course – Introduction to Molecular and Cell Biology (Bio1A) 2012 - 2015 Graduate Core Course “Fundamentals of Molecular and Cell Biology, (co- developed course, MCB200) 2008 - present Undergraduate Course on Introduction to Neurobiology 2008, 2010, Graduate Course on Advanced Cellular Neurobiology 2012, 2014, 2016 2009, 2011 Graduate Course in Advanced Developmental Neurobiology 2010 Graduate Core Course “Introduction to Neurobiology”, (Developed course) 2010 Special topics on developing Neural Circuits

TEACHING EXPERIENCE – University of California, San Diego 2007 Undergraduate Course in Developmental Neuroscience 2001 - 2006 Undergraduate Course in Mammalian Physiology 2003 - 2007 Graduate Course in Cellular Neurophysiology 2003 Graduate Course on Developmental Neuroscience, (Initiated and developed course)

Other Teaching Experience 1999 Instructor for Woods Hole Neurobiology Course 2001, 2003, Instructor for Cold Spring Harbor Course on Structure, Function and 2005, 2007, Development of Vision 2009, 2011, 2015

SERVICE: International/National/Local: 2019 Panelist, Conference in Undergraduate Women in Physics at UC Davis 2019 Guest lecturer, Summerbridge Program, San Francisco 2018 Ad hoc reviewer, Board of Scientific Counselors, NINDS 2018 External Reviewer Duke Neurobiology Program 2016 - present Scientific Advisory Board, UCSF Vision Core Grant 2016 - present Scientific Advisory Board, Center of Advanced European Studies And Research, Institute of the Max Planck Society, Bonn 2016-2017 Organizer Janelia meeting on Electrical Synapses 2016-2017 Organizer Janelia meeting on Motion Vision: circuits, computations and behavior 2016 External Reviewer Stanford Neurosciences Graduate Program 2016, 2017 Guest Scientist in “Curved Blackboard”, a Berkeley Unified School District elementary school program 2016, 2017, 2019 NIH Special Emphasis Panel Study Section (ad hoc) 2012 – 2016 NIH NTRC Study Section, (sitting member) 2011 Section editor, Current Opinion in Neurobiology, Networks, Circuits and Computation 2011 Section editor, Developmental Neurobiology, Retinal Development 2010, 2011 NSF CREST Reviewer 2009 - 2013 McKnight Technology Innovations in Neuroscience Awards Committee 2008, 2010 Society for Neuroscience, “Meet the Expert” participant 2006 - 2009 NIH Biophysical and Physiological Neuroscience (F03B) study section 2007 NIH NDPR Study Section, (ad hoc) 2007 NSF Workshop on Brain Science at the Interface of Biological, Physical and Mathematical Sciences, Computer Science, and Engineering: Analysis of New Opportunities 2007 NIH Blueprint Workshop on Neural Plasticity 2005 - 2007 Planning Committee for Gordon Conference on Neural Plasticity 2004 - 2006 Chair of FASEB Meeting on Retinal Neurobiology

UC Berkeley: 2019 - present Chancellor’s Advisory Committee on Life Sciences (CAC-LS) 2017- present Executive Director, Miller Institute for Basic Research 2018-present Alternative member of Animal Care and Use Committee 2007 - present Participating faculty in Biophysics graduate program and Vision Science graduate program 2019 Campus review for Edward Mallinckrodt, Jr. Foundation Grants for Biomedical Research 2019 Ad hoc Member Diversity Life Sciences Search Committee 2019 Panelist, Stanford Diversifying Academia, Recruiting Excellent (DARE) Doctoral Fellowship Program 2018 Panelist, Women in STEAM event held by the WISETheme Program, Foothill dorm 2017 Graduate Admissions Helen Wills Neuroscience Institute 2017 Speaker at “Let’s have a great time doing science” 2017 Reviewer of Graduate Fellowships for Life Sciences 2016, 2017 Member Faculty Search Committee, Division of Neurobiology 2016 – 2017 Faculty Member of the Climate Committee for HWNI Graduate Program 2016, 2017, Presented a talk on How to Present Research at Summer Undergraduate Research 2018, 2019 Fellowships program 2013 - 2018 Head, Division of Neurobiology, Dept. of Molecular and Cell Biology 2013 - 2018 Executive Committee Helen Wills Neuroscience Institute 2009 - 2015 Chancellor’s Advisory Council on Biology 2016 Reviewed proposals for Summer Undergraduate Research Fellowships (SURF) 2015 Faculty Panel at the GSI Training Day 2015, 2016 Hosted Sally Ride Science Camp for Girls for day in lab 2015 Presented a talk on How to Fund a Research Lab at Summer Undergraduate Research Fellowships program 2015 Presented at Open MIC, a UC Berkeley workgroup focused on microscopy and quantitative imaging 2014 Participated in “Expanding Potential: A workshop on navigating the hurdles faced by women in STEM” sponsored by the Synthetic Biology Research Center 2014, 2017 Hosted Mills College Neuroscience Class 2014 Reviewer for BRAIN R&D Tri-Campus Initiative 2012 Reviewer of Brain Research Foundation Scientific Innovator Awards 2012 Committee on MCB Undergraduate Awards 2012 Search Committee for Dean of School of Optometry 2010 – 2015 Organizer of Neuroscience Seminar Series 2010 Amgen Scholar Application Evaluator 2009 - 2012 Organizer of Helen Wills Neuroscience Retreat 2009 - 2013 Animal Care and Use Committee 2007 – 2012, Graduate Admissions for Department of Molecular and Cell Biology 2019 2008 - 2013 Search committee for Bowes Research Fellows Program, (Chair, 2009)

2008 - 2015 Interviewer for Regents and Chancellors Scholarships (CUSH) 2008 - 2016 Faculty Sponsor to Cal Opportunity Scholars 2011 Participant in undergraduate panel discussion “Research Night”, MCBcDNA 2010 Participant in MCB undergraduate “Meet the Faculty” lunch 2009 Participant in undergraduate “Meet the Faculty” dinner, Stern Hall 2009, 2010, Participant in Miller Fellow Panel on “Applying for Faculty Positions” 2016 2007 – 2012 Advisory Committee for the NIH grant "Scan of protein space for optical voltage probes.” PI Lawrence Cohen

UC San Diego: 2006 - 2007 Chancellor Advisory Committee on the Status of Women 2005 Member, Biophysics Faculty Search Committee, Physics Department 2005, 2006 Co-chair, UCSD, Faculty Search Committee 2005 - 2007 Neurosciences Graduate Program Seminar Committee 2003 - 2007 Graduate Admissions for Division of Biological Sciences 2002 - 2007 Graduate Student Advisor 2001 - 2007 Neurosciences Graduate Program Minor Proposition Committees 2002 - 2004 Graduate Committee, Division of Biological Sciences 2002 - 2004 Computational Neuroscience Executive Committee

Ad Hoc referee: Cell, Development, Journal of Neuroscience, Journal of Neurophysiology, Journal of Neurobiology, Journal of Comparative Neurology, Nature, Nature Neuroscience, Neuron, Science, Vision Research, Visual Neuroscience, National Eye Institute, National Science Foundation, PloS Biology, Israeli Science Foundation

2005 - 2010 Contributor to Faculty of 1000

EDITORIAL BOARDS: 2018 – present Associate Editor, Journal of Neuroscience 2017 – present Royal Society, Open Biology 2017 – present Current Opinion in Neurobiology 2007 - present Journal of Neurophysiology 2006 - present Neural Development

TRAINEES: Predoctoral (dates, program, awards, current position) • Christiane Voufo (2018 – present, HWNI) • Josh Tworig (2017 – present, MCB, NSF Predoctoral Scholar) • Corey Webster (2017 – 2019, MCB, NIH NRSA Predoctoral Fellowship) • Mathew Summers (2016 – present, MCB, NSF Predoctoral Scholar ) • Malak El-Quessny (2016 – present, HWNI, NIH NRSA Predoctoral Fellowship) • Franklin Caval-Holme (2015 – present, HWNI, NIH NRSA Predoctoral Fellowship) • Ryan Morrie (2013 – 2018, MCB, NSF Predoctoral Scholar, University Dissertation Year Award, currently postdoctoral researcher at UCSF) • Anna Vlasits (2012 – 2017, HWNI, NSF Predoctoral Scholar, NIH NRSA Predoctoral Fellowship; currently postdoctoral researcher with Thomas Euler and Philip Berens at Center of Integrative Neuroscience, Tübingen University, Germany) • David Arroyo (2011 – 2016, MCB, NSF Predoctoral Scholar, NIH NRSA Predoctoral Fellowship; currently a Regulatory Affairs Specialist at Medtronics) • Alana Firl (2010 – 2014, Vision Sciences, Biophysics training grant; currently New Biology Postdoctoral Fellow, UC Davis) • Lowry Kirkby (2009 – 2014, Biophysics, Boehringer Ingelheim Fonds Fellow, NSF Predoctoral Scholar; currently postdoctoral researcher at UCSF) • Aaron Hamby (2008-2013, MCB, NIH NRSA Predoctoral Fellow; currently working in biotech at Ingenuity Inc.) • Kevin Ford (2006 – 2011 MCB, NIH NRSA Predoctoral Fellow; data scientist/manager, Counsyl ) • Will Barkis (2006 – 2009, UCSD Neuroscience, AAAS Science Policy Fellow; Director, Mozilla Gigabit Community Fund, Mozilla Foundation • Justin Elstrott (2004 – 2009, UCSD Computational Neuroscience, NSF Predoctoral Fellow; Scientific Manager, Genentech Research and Early Development, Genentech Corp.) • Aaron Blankenship (2004 – 2009, UCSD Neuroscience, NIH NRSA Predoctoral Fellow; IT Consultant Biologics at Bayer) • Ethan Hua (2006 – 2008, UCSD Masters, UC Davis medical school) • Tim Dunn (2003 – 2008, UCSD Biological Sciences, self employed) • Kristi Hansen (2002-2004, UCSD Masters, biology graduate student, Univ. New Mexico) • Christine Torborg (2001-2004, UCSD Neuroscience, postdoctoral researcher, NINDs policy analyst) • Bryan Hwang (1999-2000, HHMI intern at NIH, Radiologist, Mountain View, CA) • Anu Bansal (1998-1999, HHMI intern at NIH, Radiologist, Boston, Massachusetts)

Postdoctoral • Alexander Tiriac (2016 – present) • Melanie Lee (2016 – 2017); Bioinformatics scientist at One Lambda/Thermo Fisher Scientific • Juliana M Rosa (2014 – 2016), Marie Curie Postdoctoral fellow at the National Hospital of Paraplegics, Toledo, Spain • Rémi Bos (2013 – 2016; Permanent position, Institut de Neurosciences de la Timone ) • Georgeann Sack (2011 – 2014, Vision Sciences Training grant; Postdoctoral NRSA, Communications Director Helen Wills Neuroscience Institute) • Michal Rivlin (2009 – 2013, recipient of Human Frontier Science Program Award; Assistant Professor at the Weitzmann Institute) • Wei Wei (2008 – 2011, Associate Professor at University of Chicago) • Anastasia Anishenko (2005-2009, Engagement Manager, Quid Inc.) • Tony del Rio (2004- 2006, Research Scientist, Boston Biomedical, Inc. • Chih-Tien Wang (2004-2006, Associate Professor, National University of Taiwan) • Sally Firth (2002-2005, Lecturer, University of Queensland) • Michael Colicos (2002-2003, Associate Professor, University of Calgary) • Joshua Singer (1998-2000, Associate Professor, University of Maryland) • Richard Harris (1998-2000, Research Professor, University of Michigan) • Rukmini Mirotznik (1999-2000, scientific editor)

Undergraduate research mentoring (UC Berkeley only): • Kali Malham, (2018) NSF REU scholar • Meghna Srivastava (2017 – 2020) • Kayla Maanum (2017 – 2019), recipient of Marion Diamond Award for leadership in research and training from Department of Integrative Biology • Yizhen Zhang (2016 - 2019) • Amanda Gonzales (2016), AMGEN Scholar, MARC program, currently PhD student MCB, UC Berkeley • Carries Bi (2015-2016) • Hans Baertsch (2014- 2015), MCB and Psychology, currently medical student at Keck Medical School, USC • Chin-Hsiu (Shaw) Hsu (2014 – 2015), recipient of MCB I. L. Chaikoff Memorial Award, currently graduate student in Biophysics at Stanford. • Razvan Druma (2013 – 2014), recipient of MCB I. L. Chaikoff Memorial Award, 2014 • Lucilla Chalmers (2011 – 2013), recipient of MCB Outstanding Scholar award, 2013 • Gal Sadik (2011 – 2012), MCB undergraduate • Kaili Zhou (2008-2011), recipient of MCB Winer award for top student in Neurobiology, 2011. Currently in medical school at UCSF • Aude Felix (2009-2010), Berkeley Graduate visiting scholar • Shri Vyas, (2008-2011), MCB undergraduate (graduated 2011) • Angel Espinoza, (Summer 2014), NSF REU student • Stephanie Guyot-Sionest (Summer, 2013; Vassar) • Yarely C Davila Vazquez (2011), NSF REU summer program, 2011 • Sarah Grundeen (2010), HWNI summer research program

INVITED LECTURESHIPS/KENOTE LECTURES: (National and International conferences and seminar series, last 10 years): upcoming: Weizmann Institute, UCSF, FENS

2019 – Keystone Symposia on “Mammalian Sensory Systems Duke Neurobiology Department retreat speaker UC Berkeley Biophysics Retreat UC Berkeley Neuroscience Retreat Seminar speaker, Instituto Partner Max Planck, Buenos Aires, Argentina Keynote speaker at Society for Neuroscience meeting in Cordona, Argentina Neuroscience Seminar Series, Baylor College of Medicine University of Minnesota, Neurobiology Seminar Series University of Wisconsin, Neurobiology Seminar Series University of Louisville, Visual Neuroscience Seminar speaker, Clinical Ophthalmology Grand rounds Harvard Neurobiology Seminar Speaker

2018 – Stanford University Neuroscience Seminar Series Colloquium Symposium on “Spontaneous Activity in Brain Development” in Netherlands (turned down) Kavli Distinguished lecture, Yale University UC Berkeley Biophysics Retreat FASEB SRC “Retinal Neurobiology and Visual Processing Vollum Institute Seminar Series, Oregon Health & Science University Department of Neuroscience Seminar Series, UT Austin,

2017 – MIT Colloquium on Brain and Cognition, Reto Weilers' Farewell Symposium: Vision and Visions, Janelia Meeting on Motion Perception (organizer) International Conference on Mathematical Neuroscience, Boulder, Colorado Let’s have an Awesome Time Doing Science, Berkeley Zilkha Neurogenetic Institute Seminar, USC Medical School Klingenstein-Simons Fellows meeting McKnight Conference on Neuroscience Janelia Meeting on Electrical Synapses (Conference organizer and speaker) Invited speaker for Sather Center Board meeting Stanford University, Mind, Brain and Computation colloquium

2016 – Center for Integrative Neuroscience, University of Tübingen, Germany Northwestern University Interdepartmental Neuroscience Student-hosted Seminar Grand Rounds, UCSF Department of Ophthalmology University of California, Berkeley Neuroscience Seminar Series Champalimaud Neuroscience Program Colloquium, Portugal SUNY Buffalo, Pioneers in Neuroscience Lecture Systems Neuroscience Journal Club, Janelia George Washington University Institute for Neuroscience Seminar Swartz Seminar in Computational Neuroscience, Yale University Bauer Guest Lectureship, Brandeis University

2015 – Society for Neuroscience Symposium Center for Neural Science Colloquium, NYU European Retina Meeting, Brighton, England MAPS2015, Strasbourg France Platform session moderator, ARVO Massey Lecture, Woods Hole Cold Spring Harbor Vision Course Lablinks, UCSF Invited speaker at COSYNE Keynote address, Janelia Farms Insect Vision meeting University of Maryland Neuroscience seminar series Colorado State University, Neuroscience Program Seminar Series Gordon Conference on Dendrites

2014 – Wayne C. Crill Lecture, Department of Physiology & Biophysics, University of Washington UCLA Neural Microcircuits symposium ARVO Mini Symposium Speaker Cold Spring Harbor Meeting Neural Circuits Cell and Developmental Symposium, UC Berkeley: Duke University Neurobiology Seminar Series Johns Hopkins University Department of Neuroscience Seminar Series University of Chicago Department of Neurobiology Seminar Series

2013 – UCSF Neuroscience Seminar series Stephen W. Kuffler Centenary Symposium, Rockefeller University University of Utah Neuroscience Seminar series Excitatory Synapses and Brain Function Gordon Conference, Les Diablerets, Switzerland Weill/Cornell Progress in Neuroscience Seminar Series, Sloan-Kettering, University of California, San Diego Neurosciences Graduate Program Seminar Series Washington University, St. Louis, Vision Science Seminar Series Einstein University seminar series U. Penn, Penn Neuroscience Scholar in Residence Cold Spring Harbor Asia Francis Crick Symposium on Neuroscience, entitled "The Changing Brain", Suzhou China Inhibition in the CNS, Gordon Research Conference, Les Diablerets, Switzerland (turned down) Dendrites: Molecules, Structure, Function, Gordon Research Conference, Les Diablerets, Switzerland (turned down)

2012 – Yale University, CNNR Seminar Series Max Plank Institute of Neurobiology Distinguished Speakers Series HWNI Redwood Center for Theoretical Neuroscience Summer Course, Invited lecturer Cold Spring Harbor Imaging Course, invited lecturer Cold Spring Harbor Meeting on Neural Circuits: from Structure to Function National Institutes of Health Seminar Series FENS Symposium Speaker, Barcelona Janelia Farms meeting Constructing Neural Circuits 2011 – Heller Lecture, Hebrew University, Jerusalem, Israel Special Lecture 2011 Society for Neuroscience meeting University of North Carolina Neuroscience Seminar Series U.C. Davis Neuroscience seminar series Picower Institute, MIT Departmental Seminar, École Normale Superior, Paris, France Departmental Seminar, Institut Pasteur, Paris, France Departmental Seminar, Institut du Fer à Moulin, Paris, France 2010 – Kavli Symposium, Trondheim, Norway CNRS-Jacques Monod Conference on Imaging brain circuits in health and disease Cold Spring Harbor Meeting on Neuronal Circuits: from Structure to Function Cold Spring Harbor Meeting on Axon Guidance, Synapse Plasticity and Regeneration (declined) FASEB Meeting on Retinal Neurobiology Roger Brown Loucks Lectureship in Neurophysiological Basis of Learning and Memory, University of Washington Dalhousie University Anatomy and Neurobiology Graduate Student Society Sponsored Seminar. Harvard Medical School Neurobiology seminar series UCSF Department of Ophthalmology Grand Rounds Brown University Neuroscience Department Seminar Series

2009 – Invited Lecturer at Instituto Gulbenkian de Ciência, Lisbon JFRC Conference on Constructing Neural Circuits International Union of Physiological Sciences Annual meeting, Kyoto, Japan EMBO conference on the Assembly and Function of Neural Circuits, Ascona, Switzerland Keynote speaker at European Retina Meeting in Oldenberg, Germany; Plenary lecture Keynote speaker at “Developmental Origins of Neural Circuits" symposium at University of Oregon in Eugene Stanford University Neurobiology Departmental Seminar

NIH – FUNDED RESEARCH PROJECTS: Ongoing: "Function of neural activity in developing retina" Principal Investigator: Marla B. Feller, Ph.D. Agency: National Eye Institute, National Institutes of Health R01 (EY 013528) Period: April 2002 - March 2022 The long-term objective of this project is to understand the cellular basis of spontaneous activity in the developing mammalian retina and to study the role of this activity in the development of retinogeniculate projections.

“Development of direction selectivity in the retina” Principal Investigator: Marla B. Feller, Ph.D. Agency: National Eye Institute, National Institutes of Health R01 (EY019498) Period: July 2009 -- June 2021 The objective of this grant to is to determine the cellular mechanisms underlying the development of retinal circuits that mediate direction selectivity

“Novel Optical Probe for Dopamine Release in Neural Circuits ”(BRAIN award) Principal Investigator: Marla B. Feller, Ph.D. and Markita Landry, Ph. SD Agency: National Eye Institute, National Institutes of Health R21 (R21EY029405) Period: Sept 2018 – August 2020 The goal of this proposal is to use new near-infrared optical nanosensor technology to image dopamine in the retina. This work will advance our understanding of neuromodulation, allowing us to elucidate its many impacts on normal and pathological circuits.

CORE Grant for Vision Research, U. C. Berkeley Principle Investigator: Richard H. Kramer, PI NEI ( P30EY003176) Funding dates: 8/01/2008 -7/31/2018 Total Direct Costs: $2,000,000 ($400,000 per year) Marla Feller, Director, Imaging Module

PUBLICATIONS: Original Articles (peer-reviewed):

M. El-Quessny, K. Maanum and M. B. Feller. Visual experience instructs dendrite orientation but is not required for asymmetric wiring of the retinal direction selective circuit, submitted

C. Webster, J. Tworig, F. Caval-Holme, C. Morgans, M. B. Feller. (2020) Steroid activation of TRPM3 channels modulates spontaneous synaptic activity but not retinal waves in the developing retina, eNeuro, 7(2):ENEURO.0175-19.2020

F. Caval-Holme,Y. Zou and M. B. Feller (2019). Gap junction coupling shapes the encoding of light in the developing retina, Current Biology, 2;29(23):4024-4035

A. Tiriac, B. Smith, M. B. Feller (2018). Light prior to eye-opening promotes retinal waves and eye- specific segregation, Neuron, 100(5):1059-1065.

T. Marques, M. T. Summers, G. Fioreze, M. Fridman, R. F. Dias, M. B. Feller and L. Petreanu (2018). A role for mouse primary visual cortex in motion perception, Current Biology, 28(11): 1703-1713.

R. D. Morrie and M. B. Feller (2018). A dense starburst plexus is critical for generating direction selectivity, Current Biology, 28(8):1204-1212.

J. M. Rosa, R. D. Morrie, H. C. Baertsch and M. B. Feller (2016). The contributions of rod and cone pathways to retinal direction selectivity across light intensities and through development, Journal of Neuroscience, 36(37): 9683.

D. A. Arroyo, L. W. Kirkby and M. B. Feller (2016), Retinal waves modulate an intra-retinal circuit of intrinsically photosensitive retinal ganglion cells, Journal of Neuroscience, 36 (26): 6892.

R. Bos, C. Gainer, M. B. Feller (2016). Role for visual experience in the development of the direction- selective circuits, Current Biology, 26(10):1367.

A. L. Vlasits, R. D. Morrie*, A. Bleckert*, A. Tran-Van-Minh*, C. F. Gainer, D. A. DiGregorio*, M. B.

Feller* (2016). A role for synaptic input distribution in a dendritic computation of motion direction, Neuron 16;89(6):1317-30. (*equal contributions).

J. M. Rosa*, R. Bos*, C. Fortuny, A. Agarwal, D. E. Bergles, J. G. Flannery, G. S. Sack, M. B. Feller (2015), Neuron-glia signaling in developing retina mediated by neurotransmitter spillover, Elife, 4. doi: 10.7554/eLife.09590. (*equal contributions)

R. D. Morrie and M. B. Feller (2015), An asymmetric increase in inhibitory synapse number underlies the development of a direction selective circuit in the retina, Journal of Neuroscience 35(25):9281-6.

A. M. Hamby, J. M. Rosa, C-H Hsu and M. B. Feller (2015), CaV3.2 KO mice have altered retinal waves but normal direction selectivity, Visual Neuroscience, 32:E003.

A. Firl, J. Ke, L. Zhang, J. H. Singer, and M. B. Feller (2015), Elucidating the role of AII amacrine cells in glutamatergic retinal waves, Journal of Neuroscience, 35(4): 1675-86.

S.C. Dodani*, A.Firl*, J. Chan, C. I. Nam, C. S. Onak, M. B. Feller, and C. J. Chang (2014), Copper is an endogenous modulator of spontaneous activity of neural circuits, Proceedings of the National Academy of Sciences 111(46):16280-5. (*equal contributions)

A. L. Vlasits, R. D. Morrie, C. Fortuny, J. G. Flannery, M. B. Feller, and M. Rivlin-Etzion (2014), Retinal adaptation alters excitatory input to starburst amacrine cells and switches their polarity, Neuron, 83(5):1172-84.

H. Lee, B. Brott, L. A. Kirkby, J. D. Adelson, S. Cheng, M. B. Feller, A. Datwani, C.J. Shatz (2014), “Coregulation of synaptic learning rules and synapse elimination by MHC Class I H2-Db”, Nature, 509(7499):195-200.

J. W. Triplett, W. Wei, C. Gonzalez, N. T. Sweeney, A. D. Huberman, M. B. Feller and D. A. Feldheim (2014) Dendritic and Axonal Targeting Patterns of a Genetically-Specified Class of Retinal Ganglion Cells that Participate in Image-Forming Circuits” Neural Development, 9(1):2.

L. O. Sun, Z. Jiang, M. Rivlin-Etzion, R. Hand, C. Brady, R. L. Matsuoka, K-W Yau, M. B. Feller, A. L. Kolodkin (2013), “ON and OFF direction-selective retinal circuits require different molecular mechanisms for functional assembly”, Science, 342:1241974. L. A. Kirkby and M. B. Feller (2013), “Intrinsically photosensitive ganglion cells contribute to plasticity in retinal wave circuits.”, Proceedings of the National Academy of Sciences, 110(29):12090-5.

K. J. Ford, D Arroyo, J. Kay, E. E. Lloyd, R. M Bryan Jr., J, Sanes, M. B. Feller (2013), “A role for TREK1 in generating the slow afterhyperpolarization in developing starburst amacrine cells”, Journal of Neurophysiology, 109(9) :2250-9.

A. Firl, G. S. Sack,, Z. L. Newman, H. Tani, and Marla B. Feller (2013), “Role for extrasynaptic glutamate and inhibitory neurotransmission in modulating ganglion cell participation during glutamatergic retinal waves”, Journal of Neurophysiology, 109(7):1969-78.

M. Rivlin-Etzion, W. Wei and M. B. Feller (2012), Visual stimulation reverses the directional preference of direction selective retinal ganglion cells, Neuron, 76(3):518-25.

Ford, K.J., A. F. Felix, M. B. Feller (2012), “Cellular mechanisms underlying spatiotemporal features of cholinergic retinal waves”, Journal of Neuroscience, 18;32:850-63.

O. S. Dhande, S. Bhatt, A. Anishchenko, J. Elstrott, T. Iwasato, E. Swindell, H. P. Xu, M. Jamrich, S. Itohara, M. B. Feller and M. C. Crair (2011), “Role of Adenylate Cyclase 1 in retinofugal map formation”, Journal of Comparative Neurology. 34(12):638-45.

Blankenship A.G., A. H. Hamby, A. Firl, S. Vyas, S. Maxeiner, K. Willecke, M. B. Feller (2011), “The role of neuronal connexins 36 and 45 in shaping spontaneous firing patterns in the developing retina, Journal of Neuroscience, 31(27):9998-10008. PMC314287

Rivlin-Etzion, M., K. Zhou, W. Wei, J. Elstrott, P. Nguyen, B. Barres, A. Huberman and M. B. Feller (2011). Transgenic mice reveal unexpected diversity of On-Off direction selective retinal ganglion cell subtypes and brain structures involved in motion processing, Journal of Neuroscience, 31(24):8760-9.

Blank, M., P. Fuerst, B. Stevens, N. Nouri, L. Kirkby, D. Warrier, B. Barres, M. B. Feller, A. Huberman, R. Burgess, C. Garner (2011), “The Down Syndrome critical region regulates retinogeniculate refinement, Journal of Neuroscience, 31 (15): 5764

Dhande O. S., E. W. Hua, J. Hua, E. Guh, J. Yeh, S. Bhatt, Y. Zhang, E. S. Ruthazer, M. B. Feller and M. C. Crair, (2011) Development of single retinofugal axon arbors in normal and beta-2 knockout mice, Journal of Neuroscience, 31(9):3384-99.

Wei W, A. M. Hamby, K. Zhou, M. B. Feller (2011), “Development of asymmetric inhibition underlying direction selectivity in the retina,” Nature, 469 :402-6.

Barkis, W., K. Ford, and M. B. Feller, (2010). “A target-derived, activity-independent signal induces the transition from excitatory to inhibitory GABA signaling in the mouse retina,” Proceedings of the National Academy of Sciences ;107(51):22302-7.

Elstrott J. and M. B. Feller (2010), “Direction selective ganglion cells show symmetric participation in retinal waves during development, Journal of Neuroscience, 30(33): 11197-201.

Wei W., J. Elstrott, M. B. Feller (2010) Two-photon targeted recording of GFP-expressing neurons for light responses and live cell imaging in the mouse retina, Nature Protocols, 5(7):1347-52

Anishchenko, A., J. Elstrott, A. M. Greschner, A. Sher, A. M. Litke, M. B. Feller,* E.J. Chichilnisky*, (2010). “Receptive field mosaics of retinal ganglion cells are established without visual experience”, Journal of Neurophysiology, 103(4):1856-64 (co-senior authors).

Fuerst, P. G., F. Bruce; M. Tian, W. Wei, . J. E. Elstrott, M. B. Feller, L. Erskine, J. H Singer, R. W. Burgess (2009). DSCAM and DSCAML1 function in self-avoidance in multiple cell types in the developing mouse retina, Neuron, 64: 484-97.

Dunn, T. A., D. R. Storm, M. B. Feller (2009). Calcium-dependent increases in protein kinase-A activity in mouse retinal ganglion cells are mediated by multiple adenylate cyclases, PloS One 4(11), e7877.

Huberman AD*, W. Wei*, J. Elstrott*, B. K. Stafford, M. B. Feller#, B. A. Barres# (2009). “Genetic identification of an On-Off direction selective retinal ganglion cells subtype reveals a layer specific subcortical map of posterior motion,” Neuron, 62(3):327-34 (*co-first authors; #co-senior authors).

Blankenship, A.G., K. Ford, J. Johnson, R. Seal, R. H. Edwards, D. R. Copenhagen, and M. B Feller (2009). “Synaptic and extrasynaptic factors governing glutamatergic retinal waves,” Neuron, 62, 230- 241.

Elstrott, J., A. Anishchenko,M. Greschner, A. Sher, A. M. Litke, E.J. Chichilnisky, M. B. Feller, (2008). “Direction selectivity in the retina is established independent of visual experience and early patterned activity,” Neuron, 58, 499-506.

Wang, C-T, A. Blankenship*, A. Anishchenko*, J. Elstrott, M. Fikhman, S. Nakanishi and M. B. Feller, (2007). “GABA-A receptor-mediated signaling alters the structure of spontaneous activity in the developing retina”, Journal of Neuroscience, 27:9130-40. (*co-second authors).

Dunn, T *, C-T Wang*, M. A. Colicos, M. Zaccolo, L. M. Dipilato, J. Zhang, R. Y. Tsien, M B. Feller, (2006). “Imaging of cAMP levels and PKA activity reveals that retinal waves drive oscillations in second messenger cascades”, Journal of Neuroscience, 26:12807–12815. (*co-first authors) Firth, S.I. and M.B. Feller, (2006). “Dissociated GABAergic retinal interneurons exhibit spontaneous increases in intracellular calcium concentration”, Visual Neuroscience, 23(5):807-14.

Torborg C. L., K. A. Hansen, M. B. Feller, (2005). “High frequency synchronized bursting drives eye- specific segregation of retinogeniculate projections" Nature Neuroscience, 8 (1), 72-8.

Hansen, K. A., C. L. Torborg, J. Elstrott,, M. B. Feller, (2005). “The expression and function of Connexin 36 in the developing mouse retina" Journal of Comparative Neurology,12;493,309-20.

Torborg C. L., C-T. Wang, G. Muir-Robinson, M. B. Feller, (2004). "L-type calcium channel agonist induces correlated depolarizations in mice lacking theeta subunit of nAChRs", Vision Research, 44:3347-55.

Colicos, M.C., S. I. Firth, J. Bosze, J. Goldstein, M. B. Feller (2004). “Emergence of realistic retinal networks in culture promoted by the superior colliculus,” Developmental Neuroscience, 26:406-16.

Torborg C. L and M. B. Feller (2004). “Unbiased analysis of bulk axonal segregation patterns”, Journal of Neuroscience Methods, 135: 17-26.

McLaughlin, T*. , C. L. Torborg*, M. B. Feller#, D. D. O'Leary# (2003). “Retinotopic map refinement requires spontaneous retinal waves during a brief critical period of development”, Neuron 40, 1147–1160. (*co –first authors, #co-senior authors)

Muir-Robinson G., B. Hwang, and M. B. Feller (2002). “Retinogeniculate axons undergo local segregation in the absence of eye-specific layers”, Journal of Neuroscience 22(13), 5259-64.

Harris R. E., M. G. Coulombe, M. B. Feller (2002). “Dissociated retinal neurons form periodically active synaptic circuits”. Journal of Neurophysiology 88(1), 188-95.

Singer. J. H., R. R. Mirotznik, and M. B. Feller (2001). “Potentiation of L-type calcium channels reveals non-synaptic mechanisms that corelate spontaneous activity in the developing mammalian retina”, Journal of Neuroscience 21(21), 8514-8522.

Bansal A., J. H. Singer, B. J. Hwang, W. Xu, A. Beaudet, and M. B. Feller (2000), “Mice lacking specific nAChR subunits exhibit dramatically altered spontaneous activity patterns and reveal a limited role for retinal waves in forming ON/OFF circuits in the inner retina”, Journal of Neuroscience 20(20), 7672-7681.

Stellwagen, D., C. J. Shatz, M. B. Feller (1999). “Dynamics of retinal waves are controlled by cyclic- AMP”, Neuron, 24,673-685.

Butts, D. A., M. B. Feller, C. J. Shatz, and D. Rokhsar (1999). Retinal Waves are governed by collective network properties”, Journal of Neuroscience 19 (9),3580-3593.

Penn, A. A., P. A. Riquelme, M. B. Feller, and C. J. Shatz (1998). “Spontaneous activity drives competition in retinogeniculate patterning, Science, 279, 2108-2112.

Messersmith, E. M., M. B. Feller, and C. J. Shatz, (1997). “Migration of neocortical neurons in the absence of functional NMDA receptors”, Molecular and Cell Biology 9, 347-357.

Feller, M. B., D. A. Butts, H. Aaron , D. Stellwagen, D. Rokhsar, and C. J. Shatz (1997). “Dynamic processes shape spatiotemporal properties of spontaneous retinal waves”, Neuron 19, 293-306.

Feller, M. B., D. P. Wellis, D. Stellwagen, F. S. Werblin, and C. J. Shatz (1996). “Cholinergic synaptic transmission is required for wave propagation in developing retina”, Science 272,1182-1187.

Feller, M.B., K. R. Delaney, and D. W. Tank (1996). Presynaptic calcium dynamics at the retino-tectal synapse in frog optic tectum”, Journal of Neurophysiology 76 (1), 381-400.

REVIEWS: (peer reviewed)

A. S. Mauss*, A.L. Vlasits** A. Borst#, M. B. Feller# (2017), “Visual Circuits for Direction Selectivity”, Annual Review Neuroscience, 40:211-230. (*,equal contributions)

D. A. Arroyo and M. B. Feller (2016), “Spatiotemporal features of retinal waves instruct the wiring of the visual circuitry”, Frontiers in Neural Circuits, 10:54.

R. D. Morrie and M. B. Feller (2016), “Development of synaptic connectivity in the retinal direction selective circuit”, Current Opinion in Neurobiology 40, 45-52.

L. A. Kirkby, G. S, Sack, A. Firl and M. B. Feller (2013), “A role for correlated spontaneous activity in the assembly of neural circuits”, Neuron 80(5): 1129-44.

Wei, W and M. B. Feller (2011), Organization and development of direction selective circuits in the retina. Trends in Neuroscience, 34:638-45.

Ford, K., A. F. Felix, M. B. Feller (2011), “Assembly and disassembly of a retinal cholinergic network”, Visual Neuroscience, 29(1):61-71.

Blankenship and M. B. Feller (2010), Mechanisms underlying spontaneous patterned activity in developing neural circuits, Nature Reviews Neuroscience 11 (1): 18-29.

J. Elstrott and M. B. Feller (2009), Development of direction selectivity: a tale of two circuits, Current Opinion in Neurobiology, 19(3), 293-7.

Huberman, M. B. Feller and B. Chapman (2008), Mechanisms Underlying Development of Visual Maps and Receptive Fields, Annual Review of Neuroscience, 31, 479-509.

T. A. Dunn and M. B. Feller (2008). Imaging second messenger dynamics in developing neural circuits, Developmental Neurobiology 68(6), 835-44.

Torborg C. L. and M. B. Feller (2005). Spontaneous patterned retinal activity and the refinement of retinal projections, Progress in Neurobiology 76(4):213-235.

Feller, M. B. and M. Scanziani (2005). A precritical period for plasticity in visual cortex, Current Opinion in Neurobiology 15(1), 94-100.

Firth S. I., C-T Wang, M. B. Feller (2005). Retinal Waves: Mechanisms and function in visual system development. Cell Calcium 37 (5), 425-32.

Feller, M. B. (2002). The role of nAChR-mediated spontaneous retinal activity in visual system development, Journal of Neurobiology, 53 556-567

Roerig B. and M. B. Feller (2000). Neurotransmitters and Gap Junctions in Developing Neural Circuits, Brain Research Reviews, 32,86-114.

Feller, M. B. (1999). Spontaneous Correlated Activity in Developing Neural Circuits, Neuron 22, 653- 656.

INVITED REVIEWS:

A. Tiriac AD M. B. Feller (2019). “Embryonic neural activity wires the brain”. Science 364 (6444), 3-4.

M. B. Feller (2018). “The value of undergraduate teaching for research scientists”, Neuron, 19 (6):1113-1115.

R. D. Morrie and M. B. Feller (2017). “Motion Vision: Cortical Preferences Influenced by Retinal Direction Selectivity”, Current Biology, 27:R710-11

J. M. Rosa and M. B. Feller (2014). “Neurodevelopment: A novel role for activity in shaping retinal circuits (Dispatch)”, Current Biology, 24(19):R964-6

K. Ford and M. B. Feller (2012). “Formation of Early Retinal Circuits in the Inner-plexiform Layer”, in Webvision: The organization of the vertebrate retina, H. Kolb, E. Fernandez, R. Nelson, http://www.insight.med.utah.edu/Webvision/index.html.

M. Feller (2012), Cortical development: the sources of spontaneous correlated activity (Dispatch), Current Biology 22, R91-3

M. B. Feller and Y. H. Sun (2011), Introduction to special issue on retinal development. Developmental Neurobiology 71(12):1131-2.

P. Dayan, M. Feller, D. Feldman (2011), Networks, circuits and computation, Overview of special issue on Networks, Circuits and Computation, Current Opinion in Neurobiology, 21 (5): 661-3.

Anishchenko, M. B. Feller (2009). Go with the Flow – but Only in One Direction, Neuron (preview), 64, 152-154. J. B. Demb and M. B. Feller (2009). Neuroscience: Activity Acts Locally, Nature, 460, 961-3.

M. B. Feller (2009). Retinal waves are likely to instruct the formation of eye-specific retinogeniculate projections (Debate), Neural Development, 4:24.

T. del Rio and M. B. Feller (2006). Early retinal activity and visual circuit development, Neuron (preview), 52, 221-2.

Feller M. B. (2004). Retinal waves drive calcium transients in undifferentiated retinal cells, Journal of Neurophysiology (Editorial Focus), 91(5):1940.

Feller, M. B. (2003). Visual system plasticity begins in the retina (Preview), Neuron, 38. 3-4.

Feller, M. B. (1999). “Formation of Early Retinal Circuits in the Inner-plexiform Layer”, in Webvision: The organization of the vertebrate retina, H. Kolb, E. Fernandez, R. Nelson, http://www.insight.med.utah.edu/Webvision/index.html.

BOOK CHAPTERS: A. Hamby and M. B. Feller (2012). The development of retinal direction selectivity in The New Visual Neurosciences, MIT Press M. B. Feller and Daniel Kerschensteiner (2012). Retinal waves and their role in visual system development in Comprehensive Developmental Neuroscience, Yehezkel Ben-Ari, ed., Elsevier Press.

M. B. Feller and E S. Ruthazer (2009). Activity in visual system development in Developmental Neurbiology, G. Lemke, ed., Academic Press: Oxford.

P. Wenner and M. B. Feller (2008). Spontaneous patterned activity in developing neural circuits, in Encyclopedia of Neuroscience, Larry R. Squire, ed., Academic Press, Oxford.

M. B. Feller and E S. Ruthazer (2008). Activity in visual system development. in Encyclopedia of Neuroscience, Larry R. Squire, ed., Academic Press, Oxford.

T. del Rio and M. B. Feller, (2007). Neural activity and visual system development, Handbook of Behavior and Comparative Neuroscience.

M. B. Feller and Aaron G. Blankenship (2007). The function of the retina prior to vision – the phenomenon of retinal waves and retinotopic refinement, The Mouse Visual System, MIT Press

ORIGINAL ARTICLES – Physics:

Mullin, C. S., D. Kim, M. B. Feller, Y. R. Shen (1995) Picosecond Studies of Optical Second Harmonic Generation in Atomic Vapor, Physical Review Letters 74, 2678-2682.

Ouchi, Y., M. B. Feller, T. Moses and Y. R. Shen, (1992). Surface Memory Effect at the Liquid-Crystal- Polymer Interface, Physical Review Letters 68 (20), 3040-3043.

Y. R. Shen, W. Chen, M. B. Feller, J. Y. Huang, and R. Superfine. (1991). Probing the Mechanisms for Surface-Induced Alignment of Liquid Crystals, Molecular Crystal Liquid Crystal 207, 77-85.

Chen, W., M. B. Feller, and Y. R. Shen, (1991). Investigation of Anisotropic Molecular Orientational Distributions of Liquid Crystal Monolayers by Optical Second Harmonic Generation, Physical Review Letters 63, 2665-2668.

Feller, M. B., W. Chen, and Y. R. Shen , (1991). Investigation of Surface-Induced Alignment of Liquid Crystal Molecules by Optical Second Harmonic Generation, Physical Review A 43, 6778- 6792.

Stehlin, T., M. B. Feller, P. Guyot-Sionnest, and Y. R. Shen (1989). Optical Second Harmonic Generation as a Surface Probe for Non-Centrosymmetric Media, Optics Letters 13, 389-391.

Chen, W., M. B. Feller, P. Guyot-Sionnest, C. S. Mullin, H. Hsiung, T. Rasing, andY. R. Shen, (1989). Second Harmonic Generation Studies of Liquid Crystal Monolayers and Films, SPIE 1056, 104-108.