bioRxiv preprint doi: https://doi.org/10.1101/2021.04.14.439064; this version posted April 14, 2021. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. All rights reserved. No reuse allowed without permission. Iron-rich cortical pathology in FTLD 1 Joint ex vivo MRI and histology detect iron-rich cortical gliosis in Tau and TDP-43 proteinopathies M. Dylan Tisdall1, Daniel T. Ohm2, Rebecca Lobrovich2, Sandhitsu R. Das2, Gabor Mizsei1, Karthik Prabhakaran2, Ranjit Ittyerah1, Sydney Lim1, Corey T. McMillan2, David A. Wolk2, James Gee1, John Q. Trojanowski3, Edward B. Lee3, John A. Detre1,2, Paul Yushkevich1, Murray Grossman2, David J. Irwin2,3 1Radiology, Perelman School of Medicine, University of Pennsylvania 2Neurology, Perelman School of Medicine, University of Pennsylvania 3Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania Corresponding authors: David J. Irwin Frontotemporal Degeneration Center (FTDC) University of Pennsylvania Perelman School of Medicine Hospital of the University of Pennsylvania 3600 Spruce Street, Philadelphia, PA 19104 (215)-662-7682
[email protected] M. Dylan Tisdall Department of Radiology University of Pennsylvania Perelman School of Medicine D406 Richards Building 3700 Hamilton Walk, Philadelphia, PA 19104 bioRxiv preprint doi: https://doi.org/10.1101/2021.04.14.439064; this version posted April 14, 2021. The copyright holder for this preprint (which was not certified by peer review) is the author/funder. All rights reserved. No reuse allowed without permission. Iron-rich cortical pathology in FTLD 2 (215)- 573-4003
[email protected] bioRxiv preprint doi: https://doi.org/10.1101/2021.04.14.439064; this version posted April 14, 2021.