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Curriculum Vitae of Wei Guo Title CURRICULUM VITAE OF WEI GUO TITLE: ASSISTANT PROFESSOR Address: Department of Animal Science University of Wyoming 1000 E. University Ave. (Dept. 3684) Laramie, WY 82071 Office: (307) 766-3429; Mobile: 608-239-4375 Email: [email protected] or [email protected] PERSONAL STATEMENT I have tenure-track appointment as Assistant Professor in the Department of Animal Science with 67.5% research, 27.5% teaching, and 5% service. A major focus of Guo lab (Muscle Biology Laboratory, MBL) is to understand the molecular basis and cell signaling pathways underlying cardiomyopathies, heart failure and skeletal muscle myopathy. Another major focus of MBL is to study the life course impact of fetal programming on cardiac and skeletal muscle development and function. Understanding of these mechanisms may help to develop novel therapeutic strategies for treatment of cardiac and skeletal muscle diseases, and also help to improve meat quality and quantity in livestock. My three ongoing projects are to 1) decipher the molecular mechanisms of RNA binding motif 20 (RBM20)-mediated myocardial stiffness in heart failure with preserved ejection fraction (HFpEF); 2) understand the molecular mechanisms regulating skeletal muscle function and metabolism; and 3) determine the impact of maternal obesity on striated muscle function of offspring during life course. My teaching philosophy is to provide a classroom environment where students are encouraged to express their own ideas and participate in their education experience. Although I stress individual responsibility for learning in the class, I also provide explanation and guidance regarding the course materials and subject matter. I want students to enjoy their interaction in my classroom and to be challenged by the intellectual discussion of course materials. EDUCATION 2009 Postdoctoral Fellow in Animal Science/Nutritional Science, University of Wisconsin-Madison, WI. 2004 Ph.D. in Molecular/Cellular Biology China Agricultural University, Beijing, China. 1999 B.S. in Biotechnology, China Agricultural University, Beijing, China. PROFESSIONAL EXPERIENCE 2013-Present Assistant professor, Animal Science, University of Wyoming, Laramie, WY 2013-present Faculty member of Molecular Cellular Life Science Program, University of Wyoming, Laramie, WY 2013-present Faculty member of Biomedical Science Program, University of Wyoming, Laramie, WY 2013-present Faculty member of the Center for Fetal Programming, University of Wyoming, Laramie, WY 2013-present Faculty member of the Center for Cardiovascular Research and Alternative Medicine, University of Wyoming, Laramie, WY 2013 Research Scientist, Cell and Regenerative Biology at School of Medicine and Public Health, University of Wisconsin-Madison, WI 2011-2013 Research Scientist, Minitube of America, Inc., Verona, WI 2009-2011 Research Scientist, Animal Science, University of Wisconsin-Madison, Madison, WI 2005-2009 Research Associate, Animal Science and Nutritional Science, University of Wisconsin-Madison, WI 2004-2005 Research Assistant Professor, National Institute of Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China HONORS AND AWARDS 2018 Wyoming AES 2018 Outstanding Young Scientist Award 2017 Session chair in the NIH IDeA Western Regional Conference 2016 Wyoming INBRE Bioinformatics Program Award 2015 Outstanding Poster Presentation Award at American Heart Association in the China-USA Cardiovascular Symposium, Orlando, FL 2014 Young Investigator Outstanding Presentation Award at the 9th Annual ACRE/CNAHA Cardiovascular Research Symposium of American Heart Association, Chicago, IL. 2014 Session Chair at Xi’an International Cardiovascular Forum and the 19th Xijing- Mayo Clinic Cardiovascular Symposium, Xi’an, China. 2011-2013 Honorary fellow, Animal Science, University of Wisconsin, Madison, WI 2012 Abstract and Oral presentation Award for Excellence at International Meeting of Myofilament Protein Function, Madison, WI 2005 Second Place Award for Science and Technology Award from Beijing Municipality, Beijing, China 2004 First Place Award for Scientific and Technological Achievements from Chinese Academy of Agricultural Sciences (CAAS), Beijing, China 2003 Award for Technology Excellence at Annual meeting of State Key Lab, Beijing, China 1996-1999 First-class Scholarship at College of Biological Sciences of China Agriculture University, Beijing, China PROFESSIONAL SERVICE 2018-oresent Ad hoc reviewer for Michigan Diabetes Research Center Regional Grant program 2018-present Ad-Hoc grant reviewer for National Natural Science Foundation of China 2018-present Grant reviewer for the American University of Beirut (AUB) grant review, Lebanon 2018-present Ad-Hoc reviewer for the Scientific Peer Advisory and Review Services division of the American Institute of Biological Science 2016-present Ad-Hoc reviewer for the Mountain West Clinical and Translational Research Infrastructure Network (CTR-IN) Pilot Grant 2016-present Abstract reviewer for the American Society of Cell Biology (ASCB) 2016-present Abstract reviewer for the American Heart Association (AHA) 2015-present Study section member for the American Heart Association (AHA) Funding Program 2010-present Journal reviewer for over 15 peer-reviewed journals including Gene, Proteomics-Clinical Applications, BBA-Molecular Cell Research, BBA-Molecular Basis of Disease, Cellular Physiology and Biochemistry, Cardiovascular Toxicology, Nutrition, Metabolism and Cardiovascular Diseases, Applied Cell Biology, Cell Cycle, International Journal of Biological Science, Journal of Cellular Biochemistry, PlosOne, Physiological Genomics, Molecular and Cellular Biochemistry, Meat Science and FEBS Letters etc. PRESENTATIONS 2018 Presentation in ECI, 2018 Myofilament meeting, Madison, WI, May 19th 2018 2018 Invited presentation in 2nd International Caparica Conference in Splicing, Lisbon, Portugal, July 18th 2018 2018 Invited presentation titled “A molecular bungee cord and its regulator in muscle tissues”, Department of Animal Science, Northwest Agriculture and Forestry University, Yangling, China. 2017 Invited presentation titled “Titin, a giant protein in Cardiomyopathies”, National Center for Cardiovascular disease, Beijing, China. 2016 Invited presentation titled “Titin and Cardiomyopathies”, National Center for Cardiovascular disease, Beijing, China. 2015 Invited presentation titled “Protein isoform transition in cardiovascular disease, fetal programming and meat quality”, China Agricultural University, Beijing, China. 2015 Presentation at Early Career Scientific Symposium in the International Society for Heart Research (ISHR), Seattle, WA. 2014 Presentation at Early Career Investigator Symposium in the Myofilament Meeting, Madison, WI. 2014 Invited presentation in the 15th Tokyo RNA Club at Noncoding RNA Regulation at RIKEN in Japan. 2014 Invited presentation at Xi’an International Cardiovascular Forum and The 19th Xijing-Mayo Clinic Cardiovascular Symposium in Xi’an China. Title: “Effect of isoform transition of sarcomeric protein- Titin on cardiomyopathies”. 2014 Invited presentation at Department of cardiology at Xijing Hospital, Fourth Military Medical University, Xi’an, China. Title: “Gene Alternative Splicing and Heart Failure”. 2014 Invited Presentation from Biomedical Science Program for the Chinese delegation. Title: “Sarcomeric protein isoform and heart muscle disease”. 2013 Invited presentation titled “Alternative splicing and heart disease- titin as an example”, China Agricultural University, Beijing, China. PROFESSIONAL MEMBERSHIPS 2018-present Member, American Society for Biochemistry and Molecular Biology (ASBMB) 2015-present Member, International Society for Heart Research (ISHR) 2013-present Member, International Society for Animal Genetics (ISAG) 2012-present Member, The American Society for Cell Biology (ASCB) 2010-present Member, American Heart Association (AHA) 2007-present Member, American Biophysical Society (ABS) 2004-present Member, Animal Gene Mapping Discussion Group (ANGENMAP) SERVICE ON CAMPUS 2014-present Member for Department Academic Affairs Committee 2014-present Member for Department Search Committee 2014-present Member for Graduate Admission Committee of MCLS Ph.D. Program 2014-present Member for Graduate Committee (for ten graduate students) 2014-present Chair for Graduate Committee (for three graduate students) TEACHING 2014-present ANSC4050/5050, Animal Growth and Development, 3 credits 2014-present ANSC4061/5061, Cell Signaling, 3 credits FUNDING SUPORT ONGOING SUPPORT Multi-state Hatch Grant, USDA/NIFA, Guo (PI) 10/25/2015 – 10/24/2020 Title: Molecular Mechanisms Regulating Skeletal Muscle Function and Metabolism AES Competitive Grant, Agriculture Experiment Station (AES) of University of Wyoming, USDA-NIFA, Guo (PI) 1/1/2016-12/31/2018 Title: Molecular Mechanisms Mediating the Effects of Maternal Obesity on Cardiac Function and Development in Fetuses and Offspring of Obese Mothers National Science Foundation (NSF), Guo (co-PI) 7/1/2016-6/30/2019 Title: Removal of time and fidelity constraints in MALDI-MS imaging of proteins in tissue UW-College Collaborative Grant, NIH-Wyoming INBRE; NIH P20 NIGMS 103432, Guo (co-PI) 9/10/2018 – 5/1/2020 Title: Restoring Cardiac Function in Failing RBM20-/- Rats Neogen GeneSeek Corp. Donation Funds for Research Support, Guo (PI) 2/28/2018-3/1/2020 Title: Optimal Genomic Selection in Cattle PENDING SUPPORT NIH R01HL141453 (score 33 for first submission), Guo (PI) 12/1/2018-11/30/2023 Title:
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