Connecting Global Priorities: Biodiversity and Human Health
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Cone Snail Case
Cone Snail case Cone snail molecular phylogeny Cone snail video Snail Venom Yields Potent Painkiller, But Delivering The Drug Is Tricky Updated August 4, 201510:52 AM ETPublished August 3, 20153:30 PM ET http://www.npr.org/sections/health-shots/2015/08/03/428990755/snail-venom- yields-potent-painkiller-but-delivering-the-drug-is-tricky Magician’s cone (Conus magus) The magician’s cone, Conus magus, is a fish-hunting, or piscivorous cone snail found in the Western Pacific. It is so common in some of small Pacific islands, especially in the Philippines, that it is routinely sold in the market as food. The magician’s cone attacks its fish prey by sticking out its light yellowish proboscis, from which venom is pushed through a harpoon-like tooth. It hunts by the hook-and-line method and so will engulf its prey after it has been paralyzed. To learn more about hook-and-line hunters, click here. Scientists have analyzed the venom of the magician’s cone and one of its venom components was discovered to have a unique pharmacological activity by blocking a specific calcium channel (N-type). After this venom component was isolated and characterized in a laboratory, researchers realized that it had potential medical application. By blocking N-type calcium channels, the venom blocks channels that when open convey pain from nerve cells. If this is blocked, the brain cannot perceive these pain signals. It was developed as a pain management drug, and is now chemically synthesized and sold under the trade name Prialt. This drug is given to patients who have very severe pain that is not alliviated by morphine. -
National Monitoring Program for Biodiversity and Non-Indigenous Species in Egypt
UNITED NATIONS ENVIRONMENT PROGRAM MEDITERRANEAN ACTION PLAN REGIONAL ACTIVITY CENTRE FOR SPECIALLY PROTECTED AREAS National monitoring program for biodiversity and non-indigenous species in Egypt PROF. MOUSTAFA M. FOUDA April 2017 1 Study required and financed by: Regional Activity Centre for Specially Protected Areas Boulevard du Leader Yasser Arafat BP 337 1080 Tunis Cedex – Tunisie Responsible of the study: Mehdi Aissi, EcApMEDII Programme officer In charge of the study: Prof. Moustafa M. Fouda Mr. Mohamed Said Abdelwarith Mr. Mahmoud Fawzy Kamel Ministry of Environment, Egyptian Environmental Affairs Agency (EEAA) With the participation of: Name, qualification and original institution of all the participants in the study (field mission or participation of national institutions) 2 TABLE OF CONTENTS page Acknowledgements 4 Preamble 5 Chapter 1: Introduction 9 Chapter 2: Institutional and regulatory aspects 40 Chapter 3: Scientific Aspects 49 Chapter 4: Development of monitoring program 59 Chapter 5: Existing Monitoring Program in Egypt 91 1. Monitoring program for habitat mapping 103 2. Marine MAMMALS monitoring program 109 3. Marine Turtles Monitoring Program 115 4. Monitoring Program for Seabirds 118 5. Non-Indigenous Species Monitoring Program 123 Chapter 6: Implementation / Operational Plan 131 Selected References 133 Annexes 143 3 AKNOWLEGEMENTS We would like to thank RAC/ SPA and EU for providing financial and technical assistances to prepare this monitoring programme. The preparation of this programme was the result of several contacts and interviews with many stakeholders from Government, research institutions, NGOs and fishermen. The author would like to express thanks to all for their support. In addition; we would like to acknowledge all participants who attended the workshop and represented the following institutions: 1. -
Ecological Economics and Sustainable Forest Management: Developing a Transdisciplinary Approach for the Carpathian Mountains
ECOLOGICAL ECONOMICS AND SUSTAINABLE FOREST MANAGEMENT: DEVELOPING A TRANSDISCIPLINARY APPROACH FOR THE CARPATHIAN MOUNTAINS Edited by I.P. Soloviy and W.S. Keeton Ukrainian National Forestry University Press, Lviv © Ihor P. Soloviy and William S. Keeton © Ukrainian National Forestry University Press All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, mechanical or photocopying, recording, or otherwise without the prior permission of the publisher. Published by Ukrainian National Forestry University Press Gen. Chuprynky 103 Lviv 79057 Ukraine E-mail: [email protected] Ecological economics and sustainable forest management: developing a transdisciplinary approach for the Carpathian Mountains. Edited by I.P. Soloviy, W.S. Keeton. – Lviv : Ukrainian National Forestry University Press, Liga-Pres, 2009. − 432 p. – Statistics: fig. 28, tables 67 , bibliography 686 . The modern scientific conceptions and approaches of ecological economics and sustainable forestry are presented in the book. The attention is given especially to the possibility of the integration of these concepts towards solving the real ecological and economic problems of mountain territories and its sustainable development. The ways of sustainability of forest sector approaching have been proposed using the Ukrainian Carpathian Mountains as a case study. The book will be a useful source for scientists and experts in the field of forest and environmental policies, forest economics and management, as well as for the broad nature conservation publicity. Printed and bound in Ukraine by Omelchenko V. G. LTD Kozelnytska 4, Lviv, Ukraine, phone + 38 0322 98 0380 ISBN 978-966-397-109-0 ЕКОЛОГІЧНА ЕКОНОМІКА ТА МЕНЕДЖМЕНТ СТАЛОГО ЛІСОВОГО ГОСПОДАРСТВА: РОЗВИТОК ТРАНСДИСЦИПЛІНАРНОГО ПІДХОДУ ДО КАРПАТСЬКИХ ГІР За науковою редакцією І. -
Land-Use, Land-Cover Changes and Biodiversity Loss - Helena Freitas
LAND USE, LAND COVER AND SOIL SCIENCES – Vol. I - Land-Use, Land-Cover Changes and Biodiversity Loss - Helena Freitas LAND-USE, LAND-COVER CHANGES AND BIODIVERSITY LOSS Helena Freitas University of Coimbra, Portugal Keywords: land use; habitat fragmentation; biodiversity loss Contents 1. Introduction 2. Primary Causes of Biodiversity Loss 2.1. Habitat Degradation and Destruction 2.2. Habitat Fragmentation 2.3. Global Climate Change 3. Strategies for Biodiversity Conservation 3.1. General 3.2. The European Biodiversity Conservation Strategy 4. Conclusions Glossary Bibliography Biographical Sketch Summary During Earth's history, species extinction has probably been caused by modifications of the physical environment after impacts such as meteorites or volcanic activity. On the contrary, the actual extinction of species is mainly a result of human activities, namely any form of land use that causes the conversion of vast areas to settlement, agriculture, and forestry, resulting in habitat destruction, degradation, and fragmentation, which are among the most important causes of species decline and extinction. The loss of biodiversity is unique among the major anthropogenic changes because it is irreversible. The importance of preserving biodiversity has increased in recent times. The global recognition of the alarming loss of biodiversity and the acceptance of its value resultedUNESCO in the Convention on Biologi – calEOLSS Diversity. In addition, in Europe, the challenge is also the implementation of the European strategy for biodiversity conservation and agricultural policies, though it is increasingly recognized that the strategy is limitedSAMPLE by a lack of basic ecological CHAPTERS information and indicators available to decision makers and end users. We have reached a point where we can save biodiversity only by saving the biosphere. -
Ecography ECOG-01937 Hattab, T., Leprieur, F., Ben Rais Lasram, F., Gravel, D., Le Loc’H, F
Ecography ECOG-01937 Hattab, T., Leprieur, F., Ben Rais Lasram, F., Gravel, D., Le Loc’h, F. and Albouy, C. 2016. Forecasting fine- scale changes in the food-web structure of coastal marine communities under climate change. – Ecography doi: 10.1111/ecog.01937 Supplementary material Forecasting fine-scale changes in the food-web structure of coastal marine communities under climate change by Hattab et al. Appendix 1 List of coastal exploited marine species considered in this study Species Genus Order Family Class Trophic guild Auxis rochei rochei (Risso, 1810) Auxis Perciformes Scombridae Actinopterygii Top predators Balistes capriscus Gmelin, 1789 Balistes Tetraodontiformes Balistidae Actinopterygii Macro-carnivorous Boops boops (Linnaeus, 1758) Boops Perciformes Sparidae Actinopterygii Basal species Carcharhinus plumbeus (Nardo, 1827) Carcharhinus Carcharhiniformes Carcharhinidae Elasmobranchii Top predators Dasyatis pastinaca (Linnaeus, 1758) Dasyatis Rajiformes Dasyatidae Elasmobranchii Top predators Dentex dentex (Linnaeus, 1758) Dentex Perciformes Sparidae Actinopterygii Macro-carnivorous Dentex maroccanus Valenciennes, 1830 Dentex Perciformes Sparidae Actinopterygii Macro-carnivorous Diplodus annularis (Linnaeus, 1758) Diplodus Perciformes Sparidae Actinopterygii Forage species Diplodus sargus sargus (Linnaeus, 1758) Diplodus Perciformes Sparidae Actinopterygii Macro-carnivorous (Geoffroy Saint- Diplodus vulgaris Hilaire, 1817) Diplodus Perciformes Sparidae Actinopterygii Basal species Engraulis encrasicolus (Linnaeus, 1758) Engraulis -
Migrants & City-Making
MIGRANTS & CITY-MAKING This page intentionally left blank MIGRANTS & CITY-MAKING Dispossession, Displacement, and Urban Regeneration Ayşe Çağlar and Nina Glick Schiller Duke University Press • Durham and London • 2018 © 2018 Duke University Press All rights reserved Printed in the United States of America on acid-free paper ∞ Typeset in Minion and Trade Gothic type by BW&A Books, Inc. Library of Congress Cataloging-in-Publication Data Names: Çaglar, Ayse, author. | Schiller, Nina Glick, author. Title: Migrants and city-making : multiscalar perspectives on dispossession / Ayse Çaglar and Nina Glick Schiller. Description: Durham : Duke University Press, 2018. | Includes bibliographical references and index. Identifiers: lccn 2018004045 (print) | lccn 2018008084 (ebook) | isbn 9780822372011 (ebook) | isbn 9780822370444 (hardcover : alk. paper) | isbn 9780822370567 (pbk. : alk. paper) Subjects: lcsh : Emigration and immigration—Social aspects. | Immigrants—Turkey—Mardin. | Immigrants— New Hampshire—Manchester. | Immigrants—Germany— Halle an der Saale. | City planning—Turkey—Mardin. | City planning—New Hampshire—Manchester. | City planning—Germany—Halle an der Saale. Classification: lcc jv6225 (ebook) | lcc jv6225 .S564 2018 (print) | ddc 305.9/06912091732—dc23 lc record available at https://lccn.loc.gov/2018004045 Cover art: Multimedia Center, Halle Saale. Photo: Alexander Schieberle, www.alexschieberle.de To our mothers and fathers, Sitare and Adnan Şimşek and Evelyn and Morris Barnett, who understood the importance of having daughters who -
Sustainable Agriculture Whitepaper
Sustainable Agriculture Whitepaper Jason Bradford and Craig Wichner Local ● Organic ● Sustainable ● Profitable Sustainable Farmland LP April 8, 2009 Jason Bradford, Ph.D. and Craig Wichner May 2009 FarmlandLP.com Sustainable Agriculture Whitepaper Contents 1. Framing the Discussion 2. The Impetus for Change 3. Defining Sustainable Agriculture 4. Benefits of Sustainable Agriculture 5. What A Sustainable Agriculture System Will Look Like Framing the Discussion: Sustainable Agriculture = Sustainable Society Developing a sustainable agriculture is a necessary part of creating a sustainable society. The root of the word sustainable is the verb, to sustain, which means to nourish and prolong. In social and environmental contexts we say something is sustainable when we believe it can persist indefinitely without exhausting resources or causing lasting damage. The actions we take as individuals are at the core of both the problems and the solutions. Just by purchasing conventional goods at your local supermarket, you cause 4 lbs of pesticides to be put into the environment each year. The food supply chain averages of 4200 miles to reach your plate, when it could come from local farms and use a fraction of the transportation fuels. And the 2.6 acres of U.S. farmland (your pro-rata share) have lost 50% of the carbon in the soil since 1907, the equivalent CO2 of burning 90 barrels of oil – on top of your normal carbon emissions. Cumulatively, agriculture impacts our society at a scope and scale that few appreciate, far beyond the initial realms of our food safety, quality, and the local environment. Due to the scale of natural resources required to provide food, fiber and fuel to 6.7 billion people, agriculture requires continued global-scale supplies of fertile land, clean water, fossil fuels, fertilizers, pesticides, and transportation infrastructure. -
Secure Communities FY 2011 Budget in Brief
FY 2011 Budget in Brief ICE FOIA 10-2674.000473 Budget-in-Brief Fiscal Year 2011 Homeland Security www.dhs.gov ICE FOIA 10-2674.000474 ICE FOIA 10-2674.000475 “As a nation, we will do everything in our power to protect our country. As Americans, we will never give in to fear or division. We will be guided by our hopes, our unity, and our deeply held values. That's who we are as Americans … And we will continue to do everything that we can to keep America safe in the new year and beyond.” President Barack Obama December 28, 2009 ICE FOIA 10-2674.000476 ICE FOIA 10-2674.000477 Table of Contents I. Department of Homeland Security (DHS) Vision and Mission.......................................................... 1 II. Fiscal Year 2011 Overview................................................................................................................. 3 DHS Total Budget Authority by Funding: Fiscal Years 2009–2011............................................... 13 FY 2011 Percent of Total Budget Authority by Organization .......................................................... 15 Total Budget Authority by Organization: Fiscal Years 2009–2011................................................. 17 III. Efficiency Review & Progress ……………………………………………………………………. 19 IV. Accomplishments …………………………………………………………………………………..21 V. Summary Information by Organization ............................................................................................ 29 Departmental Management and Operations .................................................................................... -
Libro ING CAC1-36:Maquetación 1.Qxd
© Enrique Montesinos, 2013 © Sobre la presente edición: Organización Deportiva Centroamericana y del Caribe (Odecabe) Edición y diseño general: Enrique Montesinos Diseño de cubierta: Jorge Reyes Reyes Composición y diseño computadorizado: Gerardo Daumont y Yoel A. Tejeda Pérez Textos en inglés: Servicios Especializados de Traducción e Interpretación del Deporte (Setidep), INDER, Cuba Fotos: Reproducidas de las fuentes bibliográficas, Periódico Granma, Fernando Neris. Los elementos que componen este volumen pueden ser reproducidos de forma parcial siem- pre que se haga mención de su fuente de origen. Se agradece cualquier contribución encaminada a completar los datos aquí recogidos, o a la rectificación de alguno de ellos. Diríjala al correo [email protected] ÍNDICE / INDEX PRESENTACIÓN/ 1978: Medellín, Colombia / 77 FEATURING/ VII 1982: La Habana, Cuba / 83 1986: Santiago de los Caballeros, A MANERA DE PRÓLOGO / República Dominicana / 89 AS A PROLOGUE / IX 1990: Ciudad México, México / 95 1993: Ponce, Puerto Rico / 101 INTRODUCCIÓN / 1998: Maracaibo, Venezuela / 107 INTRODUCTION / XI 2002: San Salvador, El Salvador / 113 2006: Cartagena de Indias, I PARTE: ANTECEDENTES Colombia / 119 Y DESARROLLO / 2010: Mayagüez, Puerto Rico / 125 I PART: BACKGROUNG AND DEVELOPMENT / 1 II PARTE: LOS GANADORES DE MEDALLAS / Pasos iniciales / Initial steps / 1 II PART: THE MEDALS WINNERS 1926: La primera cita / / 131 1926: The first rendezvous / 5 1930: La Habana, Cuba / 11 Por deportes y pruebas / 132 1935: San Salvador, Atletismo / Athletics -
Conus Geographus, 70% Fatality Rate
VENOMOUS CONE SNAILS (FISH - HUNTING SPECIES) Some kill people: Conus geographus, 70% fatality rate. 3 F2 4 different clades of fish-hunting cone snails harpoon tooth proboscis tip Lightning-strike cabal -Conotoxin - INCREASES Na channel conductance k-Conotoxin - Blocks K channels Others - ? k-PVIIA CRIONQKCFQHLDDCCSRKCNRFNKCV -PVIA EACYAOGTFCGIKOGLCCSEFCLPGVCFG Prey Capture Excitotoxic Neuromuscular 1 Shock 2 Block Very rapid, fish stunned Irreversible paralysis Lightning-strike cabal Lightning strike constellation -Conotoxin - INCREASES Na channel conductance k-Conotoxin - Blocks K channels -Conotoxin - Activates Na Channels Con-ikot-ikot - Inhibits Glu receptor desensitization Motor cabal Motor constellation w-Conotoxin - Blocks Ca channels a-Conotoxin - Competitive nicotinic receptor inhibitor y-Conotoxin - Nicotinic receptor channel blocker? m-Conotoxin - BLOCKS Na channel conductance Conus geographus • The Deadliest Snail in the Ocean Net Strategy Sensory Deadening Neuromuscular Block (Nirvana Cabal) (Motor Cabal) Nirvana Cabal Sedated, quiescent state Motor Cabal Neuromuscular transmission block Nirvana cabal Targeted to sensory circuitry: s-Conotoxin - 5HT3 receptor blocker * Conantokin - NMDA receptor blocker * “Sluggish” peptide “Sleeper” peptides “Weaponized” insulin Mature venom insulin is post-translationally modified Con-Ins G1 Highly expressed in venom gland Highly abundant in C. geographus venom Helena Hemami-Safavi Activity testing Adam Douglass SafaviSantosh-Hemami Karanth et al. 2015, Amnon PNAS Schlegel Venom insulin: proposed mechanism of action Adminstration of insulin causes glucose uptake from the blood into liver and muscle tissue Insulin overdose: rapid depletion of blood glucose leads to insufficient glucose supply for the brain: dizziness, nausea, coma and death Insulin shock, hypoglycemic shock Insulin as a murder weapon, the Sunny von Bülow case: American heiress and socialite. Her husband, Claus von Bülow, was convicted of attempting her murder by insulin overdose C. -
Mitochondrial Genome of Bulinus Truncatus (Gastropoda: Lymnaeoidea): Implications for Snail Systematics and Schistosome Epidemiology
Journal Pre-proof Mitochondrial genome of Bulinus truncatus (Gastropoda: Lymnaeoidea): implications for snail systematics and schistosome epidemiology Neil D. Young, Liina Kinkar, Andreas J. Stroehlein, Pasi K. Korhonen, J. Russell Stothard, David Rollinson, Robin B. Gasser PII: S2667-114X(21)00011-X DOI: https://doi.org/10.1016/j.crpvbd.2021.100017 Reference: CRPVBD 100017 To appear in: Current Research in Parasitology and Vector-Borne Diseases Received Date: 21 January 2021 Revised Date: 10 February 2021 Accepted Date: 11 February 2021 Please cite this article as: Young ND, Kinkar L, Stroehlein AJ, Korhonen PK, Stothard JR, Rollinson D, Gasser RB, Mitochondrial genome of Bulinus truncatus (Gastropoda: Lymnaeoidea): implications for snail systematics and schistosome epidemiology, CORTEX, https://doi.org/10.1016/ j.crpvbd.2021.100017. This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2021 The Author(s). Published by Elsevier B.V. Journal Pre-proof Mitochondrial genome of Bulinus truncatus (Gastropoda: Lymnaeoidea): implications for snail systematics and schistosome epidemiology Neil D. Young a,* , Liina Kinkar a, Andreas J. Stroehlein a, Pasi K. Korhonen a, J. -
DEEP SEA LEBANON RESULTS of the 2016 EXPEDITION EXPLORING SUBMARINE CANYONS Towards Deep-Sea Conservation in Lebanon Project
DEEP SEA LEBANON RESULTS OF THE 2016 EXPEDITION EXPLORING SUBMARINE CANYONS Towards Deep-Sea Conservation in Lebanon Project March 2018 DEEP SEA LEBANON RESULTS OF THE 2016 EXPEDITION EXPLORING SUBMARINE CANYONS Towards Deep-Sea Conservation in Lebanon Project Citation: Aguilar, R., García, S., Perry, A.L., Alvarez, H., Blanco, J., Bitar, G. 2018. 2016 Deep-sea Lebanon Expedition: Exploring Submarine Canyons. Oceana, Madrid. 94 p. DOI: 10.31230/osf.io/34cb9 Based on an official request from Lebanon’s Ministry of Environment back in 2013, Oceana has planned and carried out an expedition to survey Lebanese deep-sea canyons and escarpments. Cover: Cerianthus membranaceus © OCEANA All photos are © OCEANA Index 06 Introduction 11 Methods 16 Results 44 Areas 12 Rov surveys 16 Habitat types 44 Tarablus/Batroun 14 Infaunal surveys 16 Coralligenous habitat 44 Jounieh 14 Oceanographic and rhodolith/maërl 45 St. George beds measurements 46 Beirut 19 Sandy bottoms 15 Data analyses 46 Sayniq 15 Collaborations 20 Sandy-muddy bottoms 20 Rocky bottoms 22 Canyon heads 22 Bathyal muds 24 Species 27 Fishes 29 Crustaceans 30 Echinoderms 31 Cnidarians 36 Sponges 38 Molluscs 40 Bryozoans 40 Brachiopods 42 Tunicates 42 Annelids 42 Foraminifera 42 Algae | Deep sea Lebanon OCEANA 47 Human 50 Discussion and 68 Annex 1 85 Annex 2 impacts conclusions 68 Table A1. List of 85 Methodology for 47 Marine litter 51 Main expedition species identified assesing relative 49 Fisheries findings 84 Table A2. List conservation interest of 49 Other observations 52 Key community of threatened types and their species identified survey areas ecological importanc 84 Figure A1.