Fall 2012

SightThe Wilmer EyeLine Institute at Johns Hopkins

A Boost for Rising Stars The Next Generation Fund will help Wilmer recruit promising junior faculty members by reducing their medical school debt. ontents s see it cImpact a 3 Women’s Board Gift Makes Critical Tool Possible

P HOTO Wilmer’s Eric Singman tells why a high- Dear Wilmer Friends and Family, tech new machine is a “win-win-win” BY KEITH WELLER for diagnosing and treating glaucoma. Not long ago, age-related macular degeneration, or AMD, was untreatable—a major cause of blindness and the leading Impact cause of new cases of blindness in people In the Neighborhood over age 65. When there was no FDA- 4 Wilmer’s network of satellite locations approved therapy for AMD and clinical will soon expand to 10 locations research was needed to evaluate potential across Maryland. treatments, Rick and Sandy Forsythe were there for Wilmer. They supported important work here that helped lead to Cover some of today’s effective therapies. A Boost for Rising Stars When Wilmer’s research space was full 6 The Next Generation Fund will help and potentially promising new therapies Wilmer recruit promising junior could not be explored because of the lack faculty members by reducing their of additional labs, Rick and Sandy were medical school debt. there with a lead gift that allowed construction of the 60,000-square-foot Forsythe Pavilion for AMD Research. This gift made possible the addition of new faculty who have built programs in nanotechnology, regenerative Eye to Eye medicine, and genetics, and allowed Wilmer to assemble the largest group of Compassion That Knows academicians devoted to bringing to light the cause(s) of—and plotting an 10 No Borders end to—the epidemic of AMD. Faced with a grim diagnosis, Andrew And when the Wilmer faculty identified the critical need for funding to Marriott didn’t give up. His search recruit the best and brightest young minds in ophthalmology to academic brought him to the lab of Wilmer’s medicine, Rick and Sandy stepped up once again. Their generous lead gift has Peter Campochiaro. established the Next Generation Fund at Wilmer. Why are funds to support young academicians so important? As recently reported in The New York Times, the average graduate from an American medical Insight school finishes with a student loan debt in the neighborhood of $200,000. The Taking South Carolina Times also projects a shortage of some 90,000 physicians by 2020 in the U.S.—a 12 by Storm shortage that will be exacerbated by the new health care law. Meanwhile, the Lucian V. Del Priore, new director federal budget deficit has resulted in reduced funding for research, salary cuts for of the Storm Eye Institute, is one of medical scientists, less funding for training young physicians, and projections more than 100 Wilmer alumni now of reduced payments to physicians. After many years of training, a number of leading prestigious medical facilities talented young people fear that they cannot afford the reduced compensation around the world. that comes with an academic career; and they worry that grant funding needed to explore their best ideas will not be available. Events & Honors The future of academic ophthalmology requires a pipeline of men and 14 Grand Rounds at KKESH, tribute to women who are excellent doctors and great teachers—and who are excited Allan Jensen and Verdura Show at about discovering the therapies of tomorrow. Our ability to maintain the Neiman Marcus. scientific momentum in the fight against eye disease demands that we make academic careers viable and attractive to young physician-scientists who share this vision. The Next Generation Fund is one more reason I have confidence Annual Review that Wilmer will continue to be the hotbed of eye care and vision research Faculty feats for FY12, plus a thank you for generations to come. Thank you to our donors for supporting the work of 16 to our generous donors. Wilmer’s future stars.

COVER PHOTO OF WILMER’S NICK MAHONEY BY MIKE CIESIELSKI Peter J. McDonnell, MD William Holland Wilmer Professor and Director 2 SightLine FALL 2012 impact

Women’s Board Gift Makes Critical Tool Possible

Eric Singman with the valuable new SD-OCT, which allows ne of the newest tools at Wilmer’s General earlier diagnosis of glaucoma and is more sensitive to Eye Service comes with a long name—and a disease progression than traditional testing methods. big price tag. The Zeiss Cirrus Spectral Do- main Ocular Coherence Tomograph (SD- OCT for short) was purchased for just shy Oof $60,000. Much to the delight of Eric Singman, director valuable training opportunities for the residents who staff of the General Eye Services clinic at Wilmer, the Women’s the clinic. “We want to teach our residents best clinical Board of Johns Hopkins picked up the tab. practices, and we want them—and our patients—to As part of the Women’s Board annual grant process, have access to equipment that reflects cutting-edge departments across Hopkins submit applications based on ophthalmologic care,” Singman says. their most pressing needs. The board approved Singman’s Prior to acquiring the SD-OCT, residents at the clinic request for the SD-OCT, a state-of-the-art machine that had to direct patients to another location in Wilmer for is critical in the effective diagnosis and management of testing. Because the clinic is open to all patients, regardless glaucoma and optic nerve disorders. On an annual basis, the of ability to pay, a large proportion of patients are indigent, clinic sees approximately 5,000 patients who either have or uninsured, and underinsured—many because of pre-existing are being evaluated for glaucoma and related conditions. physical disabilities that limit their mobility. Sending With its high-tech capabilities, the SD-OCT enables patients elsewhere for testing was not only stressful and earlier diagnosis than traditional testing methods and is difficult for patients, but it also interrupted the flow of the more sensitive to disease progression. The machine uses clinic and greatly extended patient wait times. lasers to scan the retina and optic nerves and creates two- “Having the SD-OCT in the clinic enhances our and three-dimensional images at a microscopic level, with a ability to provide a full spectrum of services, address resolution measured in nanometers, not millimeters. these humanitarian and efficiency concerns, and train our Not only will the SD-OCT greatly benefit patients residents,” Singman says. “Getting this machine is a triple in terms of more accurate testing, but it will also provide hit for us—a win, win, win.” ■

Development 410-955-2020 Appointments 410-955-5080 3 impact

In the Neighborhood

ilmer is experiencing tremendous By the end of this year, Wilmer’s network of satellite growth—and that, of course, is a good offices—which already reaches as far west as Frederick and thing, says Wilmer Director Peter J. as far south as Odenton—will expand to 10 locations. The McDonnell. The increased demand for newest satellite location is Bethesda, just minutes away services comes from both the demo- from the nation’s capital. The need and opportunity for Wgraphic tidal wave of aging adults and the greater avail- this office arose when the trustees of Sibley and Suburban ability of new treatments for eye diseases that were, until hospitals decided to join the fold of the Johns Hopkins recently, considered untreatable. Health System. With more and more patients turning to Wilmer for routine and specialized care, the need to expand facilities and staffing could not be ignored. “Having patients wait weeks, even months, for an appointment was not acceptable,” McDonnell says. “We aspire to treat our patients the way we would like to be treated—and that means providing them with prompt appointments and world-class care.” Knowing the physical limitations of the East Baltimore campus, and understanding that many patients are not within easy driving distance of Wilmer, McDonnell looked to expand satellite locations in the greater Baltimore-Washington metropolitan community. “To be able to serve our referring ophthalmologists from around the country and all the patients who want to see us, we need more locations to provide our patients with better Drs. Yassine Daoud (far left), Ingrid Zimmer-Galler (middle convenience, flexibility, and access,” McDonnell right), and Mahsa Salehi (far right) welcome guests at explains. “We have to be where our patients are.” Wilmer's Columbia location expansion.

4 SightLine FALL 2012 Wilmer Director Peter J. McDonnell; Ronald R. Peterson, president, the Johns Hopkins Hospital; Adrienne Scott, medical director, Wilmer Parris-Castoro; and staff celebrate the grand opening of Wilmer Parris-Castoro. Scheduled to open in January, the 8,000-square- Arundel Health Systems, allowing both entities to better foot Bethesda facility will be in the same center as the meet the needs of the growing population in that area. satellite offices for Johns Hopkins Community Physicians. Nowhere has the need for expansion been as evident as Wilmer will staff a full-service center for optometry and in Columbia, the location of Wilmer’s first satellite office ophthalmology with specialists in cornea, retina, and south of Baltimore. It didn’t take long for the 3,000-square- oculoplastics, according to the site’s medical director foot facility, which opened in 2004, to reach maximum Shameema Sikder. “We’re trying to create a mini Wilmer capacity. Early this year, it was replaced by a clinic twice as that’s more accessible,” she explains. “We’ve always had large, with nearly three times as many physicians. patients from this area referred to us for our expertise, and For Yassine Daoud, assistant professor of ophthalmology now we’re bringing that expertise a little closer to our patients’ and a cornea specialist, the new space was a much- neighborhood. They’re excited about having us here.” needed improvement, offering the opportunity to hire Another addition to Wilmer’s satellite network resulted more staff and expand the practice from comprehensive from a new partnership with the Parris-Castoro Eye & Laser ophthalmology to multiple specialties. “It has led to a Center in Bel Air, Maryland. The two physicians who own more seamless transition in care,” he says. “Now I don’t the practice, Wayne Parris and Charles Castoro, approached need to send everyone who needs a retina evaluation to Wilmer more than a year ago about having Wilmer acquire Wilmer in Baltimore—because I have a colleague right next the practice, which includes clinical care facilities, a door who can care for my patients.” And when a patient’s refractive laser center, full-service optical shop, and licensed condition requires the expertise of two different specialty ambulatory surgery center, among other services. “This Bel surgeons, he notes, the patient can now have one combined Air location, plus a second location in Havre de Grace, gives surgery rather than two separate procedures, which means Wilmer and Johns Hopkins a major new presence in the potentially less risk and better outcomes for the patient. Harford County area,” McDonnell says. “It’s a really wonderful thing to be able to provide this Some 20 miles south of downtown Baltimore, the coordination of care, and our patients and referring doctors Odenton-Meade satellite office will move to a larger really appreciate that,” Daoud says. “We’re bringing world- practice site by year-end in order to accommodate increased class care to their backyard.” ■ patient demand and reduce undesirably long waits for —Marlene England appointments. The location in a new medical office building is a partnership between Johns Hopkins Hospital and Anne

Development 410-955-2020 Appointments 410-955-5080 5 A Boost for Rising Stars The Next Generation Fund will help Wilmer recruit promising junior faculty members by reducing their medical school debt. By Marlene England Photo by Mike Ciesielski

6 SightLine FALL 2012 Wilmer’s Nick Mahoney, first beneficiary of the Next Generation Fund, was happy to put down roots in Baltimore with wife, Olga, and new daughter, Penelope.

Development 410-955-2020 Appointments 410-955-5080 7 We want to attract and retain the finest core of new ophthalmologists who can help Wilmer achieve its goal of improving treatments and finding cures for eye disease. And we’ve got to reduce their financial burden. — Rick Forsythe

Wilmer Director Peter graduates are older with families and McDonnell will never forget outstanding loans, and they have to the one that got away. make ends meet,” Rick Forsythe says, “He was a brilliant young man— referencing College Board reports two fellowships in two different fields, that show the median amount of the most impressive candidate you educational debt for medical school could imagine,” McDonnell recalls. graduates in 2008 to be $155,000, caption “He told me it would be a dream with 25 percent carrying a debt come true to join the Wilmer faculty.” burden in excess of $200,000. “We But instead, the promising recruit want to attract and retain the finest accepted a position with another core of new ophthalmologists who institution—and McDonnell knows can help Wilmer achieve its goal of why. “He had several young children, improving treatments and finding more than $250,000 in student loans, cures for eye disease. And we’ve got to and wanted to buy a home for his reduce their financial burden.” family. The other institution offered The combined forces of increased Sandy and Rick Forsythe provided the him a modestly larger base salary, and graduate school debt, decreased seed money needed to launch the Next he was so anxious about paying down clinical reimbursements, and length of Generation Fund, which they hope will his debt that he went elsewhere for the grant funding cycles make it difficult put Wilmer at a significant advantage extra dollars.” to say yes to careers in academic when recruiting top talent. Losing faculty members of this medicine when the compensation is caliber to another institution or substantially higher in private practice, many consider it to be, he says. private practice is exasperating for Forsythe says. With its sole purpose William May, a California McDonnell. “There’s no better place of helping up-and-coming faculty pay ophthalmologist who serves with the for future academic stars than Wilmer, down their debt, the Next Generation Forsythes on the Board of Governors, and it’s a travesty to lose even one.” Fund gives Wilmer a significant agrees. “Those of us in private With the support of Richard advantage when recruiting top talent. practice have a hard time making new (Rick) and Sandy Forsythe, former Patients from all over the world discoveries because we don’t have the co-chairs of Wilmer’s Board of come to Wilmer for the finest laboratories and the infrastructure Governors, McDonnell is hopeful that ophthalmic care, Forsythe points and the time to do that,” he says. “We more of these “stars” will find it easier out—but they may not grasp how want to have these hugely promising to accept positions at Wilmer. the institution’s commitment to individuals at Wilmer and encourage The Forsythes have committed breakthrough research and innovative them to make important contributions $250,000 to the Next Generation teaching directly influences the quality to science.” The best way to do Fund, a new program to help reduce of care they receive. The clinician that, May says, “is by reducing the the debt of Wilmer’s most promising scientists at Wilmer focus on the overwhelming debt burden that often junior faculty recruits. The Forsythes’ care and cure of eye disease, as well pushes aspiring recruits away from gift is “seed” money for an endowment as training the next generation of the academic medicine and into private fund to be built by contributions, world’s leading ophthalmologists. practice. When I heard about Rick over time, from Wilmer’s Board of Without the trifold mission of patient and Sandy’s brilliant initiative, I Governors and other donors. care, research, and education, Wilmer insisted on having the honor of being “Nowadays, most medical school would not be the model eye institute the second contributor to this fund.”

8 SightLine FALL 2012 Endowing the Future

When Dr. William Holland Wilmer accepted the position of ophthalmologist in chief at Johns Hopkins in 1924, he did so under the condition that “sufficient endowment to The significance of lessening the debt During his fellowship at Wilmer, provide for an The LaChappelles of Wilmer recruits isn’t lost on Nicholas Mahoney worked closely with ocular extensive and Mahoney. At 30 years of age, he recently surgeon Shannath Merbs and the intensive program, clinically, scientifically and completed an American Society of oculoplastics staff. He performed pedagogically, be assured.” From its founding, Wilmer had been focused on building its Ophthalmic Plastic and Reconstructive eyelid, eye socket, and tear duct endowment to support its brilliant faculty. Surgery (ASOPRS) accredited fellowship surgery, among other specialized A recent survey conducted of current at Wilmer and joins the faculty this procedures, and became proficient faculty members identified the financial fall as the first beneficiary of the Next with technology in the operating support of junior faculty as a key priority. Generation Fund. room. Merbs and Michael Grant, chief This year, several donors directed their “Receiving help toward my student of the Oculoplastics Division, trained charitable gifts to support endowed loans impacts me greatly,” Mahoney Mahoney in the use of Wilmer’s scholarships and research funding for new faculty members who are establishing says. “I've accrued a significant computer-assisted CT scan-guided their careers in ophthalmology. While amount of debt, both from tuition navigation system, even sending the not earmarked for paying down debt, and also from living life and having a young doctor to train with surgeons in these contributions help fund living costs, family on a trainee salary.” Mahoney Germany. scholarships, and start-up research, making it and his wife, Olga, who works in The fellowship also gave Mahoney possible for up-and-coming faculty to afford a international public health, welcomed an opportunity to explore his passion career in academic medicine. their first child—“a perfect baby for teaching, and he was honored to Longtime Wilmer supporter Helen J. Iliff, a retired pediatric cardiologist and alumna girl”—earlier this year. Putting down receive Wilmer’s 2011 Fellow Resident of the School of Medicine, established a gift roots in the Baltimore-D.C. area Teaching Award. “I’m lucky to have annuity to create the Iliff Scholar at Wilmer. makes sense, Mahoney says, since it’s been offered some responsibility in The purpose of this fund is to support one of the few cities in the U.S. where the teaching of residents from the young investigators at the early stage of his wife can work internationally from Oculoplastics Division,” he says. their faculty career at Wilmer. The faculty a domestic base. “But the other major “The challenge is only more exciting member benefiting from these funds will factor in the decision, of course, was when the people you are teaching are bear the name of the Helen J. Iliff Scholar for the term of the fund’s support. Several financial,” he says, acknowledging that as capable and willing as the Wilmer years ago, Iliff helped establish the Charles it will still be several years before he is residents.” E. Iliff III, MD, Professorship in Surgical able to start saving to buy a home. McDonnell is thrilled with Ophthalmology, named for her late husband In the first few years, when trainees Mahoney’s decision to continue at whose groundbreaking career at Wilmer finish their formal education and start Wilmer. “He’s joining our faculty spanned five decades. careers, the challenges of building because he’s a star—he’s a gifted Darlene LaChappelle also funded a gift a practice, developing an academic teacher, his patients love him, and annuity to establish an endowment fund in her and her late husband Vernon’s name. The niche, and finding the right role can be even senior faculty outside the fund, in honor of Walter Stark for the expert overwhelming, Mahoney explains. “The Oculoplastics Division tell me what an care he provided to Vernon, ensures support added—and sometimes outweighing— impressive person he is,” McDonnell for new generations of Wilmer faculty. financial burden can really turn people says. “He’s exactly the type of person “I hope this gift makes it easier for away from academia.” He notes that who should and will benefit from beginning doctors to pursue their interests,” the majority of ASOPRS fellows will the Next Generation Fund—and, for LaChappelle says. “It’s a lot of hard work to accept positions in private practice, Wilmer to be successful in the future, begin with. They work for nothing for several years, not earning anything while they’re even though at the start of their we have to be able to continue to studying and plus they’re paying out. If this fellowships most had indicated a desire recruit the Nicholas Mahoneys of the can make it easier for them to do good, then ■ to stay in academia. world.” that’s what I want to do.” ■ —ME Development 410-955-2020 Appointments 410-955-5080 9 eye to eye Compassion That Knows NO BORDERS

ver the last seven years, to seek unique medical treatment for my Andrew Marriott has disease.” logged more than 90,000 Marriott was thrilled with the people miles between his home and the care he encountered at Wilmer. in Canada and the “The compassion level there knows no OWilmer Eye Institute. His first trip was a borders,” he says. “As a patient with hopeful quest for answers, which led to a disease that was taking my vision, I many more appointments, a remarkable hung on doctors’ every word.” Marriott Andrew is the type recovery of vision, and a passion to fund still remembers the encouraging promising new research. comments of Sharon Solomon, the first of person who never Marriott was in his mid-30s ophthalmologist he met at Wilmer, and takes no for an answer. when diagnosed with choroidal the above-and-beyond efforts of Peter neovascularization and subretinal Campochiaro and his colleague Quan He received a serious bleeding due to pathological myopia. Nguyen. He credits Betsy Campochiaro, A degenerative condition of the retina, in Wilmer’s Macular Degeneration diagnosis, but he this form of myopia is complicated by Center, for connecting the dots that didn’t stop searching abnormal blood vessel growth behind eventually led to his inclusion in clinical the retina, similar to what happens trials being conducted by her husband, for the best care. He in patients with age-related macular Peter. degeneration (AMD). “Andrew is the type of person who did his research and At the time, the standard treatment never takes no for an answer,” says Peter got himself into the for his condition was photodynamic Campochiaro. “He received a serious (laser) therapy, which had only transient diagnosis, but he didn’t stop searching position so he could effects for Marriott. It reduced the for the best care. He did his research leaking and bleeding but caused retinal and got himself into the position so he get into a clinical trial. damage and some blank spots in his could get into a clinical trial.” vision. Doctors predicted he would be It wasn’t easy to find a clinical trial blind before he reached retirement age. with criteria that matched Marriott’s —Peter Campochiaro This dire diagnosis didn’t sit well with condition. Most drug companies testing Marriott, a restaurant franchisee of Tim drugs for abnormal blood vessel growth Hortons and Cold Stone Creamery in beneath the retina were recruiting elderly Alberta, Canada. He immediately began patients with AMD. There was, however, researching online to learn about any a promising new opportunity. Research alternative treatments and clinical drug in several labs, including Campochiaro’s, trials that might save his vision. had shown that vascular endothelial “The Internet is a powerful resource,” growth factor (VEGF) is an important To view Andrew Marriott says, “but the information stimulus for abnormal blood vessel Marriott's patient available was hard to differentiate. What growth under the retina. VEGF is a testimonial please go to appeared to be progressive and hopeful naturally occurring protein in the body treatments were unfortunately not the that is released by tissues when oxygen http://youtu.be/RgE1dBluzDg right options for me. It was this research levels drop. This process results in the that brought me to understand that growth of new blood vessels around Wilmer was going to be the best option the oxygen-deprived tissue. VEGF is to

10 SightLine FALL 2012 The results from my first trial were instantaneous. I still remember watching a basketball game the night before the drug was administered and not being able to read the score from my hotel bed. The next morning, I was… able to see the score quite clearly.

—Andrew Marriott Wilmer’s Peter Campochiaro with a visiting Andrew Marriott, whose vision is now 20/20. blame for abnormal blood growth that testing at Wilmer and now takes developments that come along.” results in bleeding and ultimately loss supplements recommended by The clinical drug trial in which of vision. While Lucentis, an antibody Campochiaro to maintain eye health. Marriott participated has since shaped fragment that blocks VEGF, was being With no current signs of the disease the standard course of care for patients tested in clinical trials in patients with that once threatened his ability to with subretinal bleeding. Identifying AMD, it had not yet been approved. see, Marriott has 20/20 vision—and VEGF as a molecular target—and But Avastin, a full-length antibody that tremendous gratitude to the doctors at being able to successfully use anti- blocks VEGF, had just been approved Wilmer. He has been a generous donor VEGF agents in treatment—has to treat colon cancer. Immediately, a to retinal research in Campochiaro’s resulted in what Campochiaro calls “a clinical trial was started at Wilmer to lab. sea change for our patients.” Success test intravascular infusions of Avastin “I have been extremely fortunate, breeds success, he says, and researchers in young patients like Andrew Marriott choosing the right place and the right have already identified a second who had abnormal blood vessel growth time,” he says. molecular target with the promise of under the retina. “The basis and foundation of Johns multiple new approaches for treating “Andrew was thrilled to find out Hopkins Hospital and the Wilmer diseases of the retina. that we were trying new things and Eye Institute’s research departments is Marriott closely follows that he was eligible for these trials,” their true desire for patient care and Campochiaro’s work and is eager to Campochiaro says. Both doctor and sustainable health.” Realizing that celebrate the next major breakthrough patient were equally overwhelmed by much of their work goes unfunded by in eye research. “There have been more the results. the major drug companies and other advances in treatments for those with “The results from my first trial were agencies, Marriott decided to support vision loss in the last five years than in instantaneous,” Marriott recalls. “I the same type of cutting-edge research the 50 years prior,” Marriott says. “I still remember watching a basketball that led to his restored sight. tell people never to decline treatment, game the night before the drug was His generosity has provided to be an advocate for clinical trials. The administered and not being able to read critical resources for early-phase trials only way that medical professionals the score from my hotel bed. The next considered too risky by traditional can determine the effectiveness of morning, I was watching the previous funders. “With gifts like Andrew’s, treatments is to have patients put their night’s highlights. I was able to see the we’re able to test new approaches trust in the truly gifted doctors and in score quite clearly.” and novel ideas,” Campochiaro says. medical research.” ■ Marriott participated in additional “That’s part of what fuels the new —ME

Development 410-955-2020 Appointments 410-955-5080 11 insight

Taking South Carolina by Storm

Wilmer’s long-standing pattern of University College of Physicians training leaders in ophthalmology and Surgeons in New York City. continues with the appointment of He completed his residency and Lucian V. Del Priore as director of the fellowship in vitreoretinal surgery Lucian V. Del Priore is the new director of the Storm Eye Institute Storm Eye Institute at the Medical and glaucoma research at Wilmer in in South Carolina, one of the University of South Carolina. Del 1989. He holds five patents and has nation’s top 20 eye institutes. Priore is one of more than 100 developed surgical techniques for Wilmer alumni who have gone on the wet form of age-related macular to lead prestigious medical facilities degeneration. Del Priore is also one around the world. of five ophthalmic specialists in the A respected retinal physician, country who are testing a retinal surgeon, teacher, and researcher, Del implant to restore limited sight to Priore now oversees South Carolina's patients with retinitis pigmentosa. largest research and clinical faculty in His former colleagues at Wilmer ophthalmology, and the leading Level commend his success—perhaps none 1 eye trauma service in the state. The more proudly than Peter McDonnell, Storm Eye Institute has been South who trained Del Priore as a resident. Carolina’s center for the management “He is a great example of the kind of complex and serious eye diseases of people we strive to train at for 30 years and is recognized as one Wilmer…a scientist who works in the of the nation’s top 20 eye institutes. lab, a very gifted doctor, an excellent Before joining the Storm Eye teacher. It’s great to see people we Institute last fall, Del Priore served train go on to assume leadership as professor of ophthalmology and roles,” McDonnell says. ■ the first Robert L. Burch III Scholar —ME in Retinal Research at Columbia 12 SightLine FALL 2012 Wilmer Leaders Around the World

Mexico Australia Canada Japan

Since 1925, the Wilmer Eye Institute has advanced the field of ophthalmology by treating patients, training doctors, and conducting research. This tradition of excellence has a serendipitous benefit—it creates world leaders in ophthalmology.

Some 105 ophthalmologist leaders, working at locations represented here, were either trained at Wilmer or served on Wilmer's faculty. There are department chairs and deans of medicine at some of the top institutions in the world. Consequently, Wilmer leadership guides the top Europe minds in the field each day.

Development 410-955-2020 Appointments 410-955-5080 13 events

Grand Rounds at KKESH June 7, 2012 On Thursday, June 7, Wilmer history was made when faculty from the Wilmer Eye Institute and King Khaled Eye Specialist Hospital (KKESH) in Riyadh, Saudi Arabia, held a virtual Grand Rounds. Led by Wilmer Director Dr. Peter McDonnell, KKESH General Executive Director Dr. Abdul Elah Al-Towerki, and KKESH Medical Director Dr. Ashley Behrens, the event offered faculty and residents from two institutions on opposite sides of the world the opportunity to learn from each other via videoconferencing. Dr. Peter J. McDonnell, director, Wilmer Eye Institute, discusses a case with KKESH faculty.

Dr. Allan Jensen Tribute June 7, 2012

On June 7, the Wilmer Eye Institute hosted a tribute for Dr. Allan Jensen. Dr. Jensen and his wife, Claire, have been incredibly generous philanthropists to Johns Hopkins University through their gifts to the School of Medicine, the Peabody Institute, Sheridan Libraries, and the Wilmer Eye Institute.

L to r: Mrs. Claire Jensen, Dr. Allan Jensen, and Dr. Peter J. McDonnell.

Verdura Trunk Show May 12, 2012 On May 12, a Verdura fine jewelry trunk show was held at Neiman Marcus, Chevy Chase, to benefit the Wilmer Eye Institute. Mrs. Beth Glassman, the event chairperson, gave a testimonial to express her gratitude to Wilmer and the event’s honorary hostess, Dr. Susan Bressler. L to r: Dr. Susan Bressler, Neiman Marcus General Manager Martha Slagle, and Mrs. Beth Glassman.

14 SightLine FALL 2012 honors

Dr. Morton F. Goldberg accepts the foundation's The Foundation Fighting Blindness presented Builders of Sight Clinical its Builders of Sight Clinical Research Award to Dr. Morton F. Research Award. Goldberg. This is a new honor that was given to Dr. Goldberg to recognize his extraordinary efforts that are making clinical advances possible. Dr. Goldberg has greatly contributed to the growth of the Wilmer Eye Institute’s clinical research program, and has nurtured the best sight-saving science as a member of the foundation’s Scientific Advisory Board since the early 1970s, and as chairman of the newly named Foundation Fighting Blindness Clinical Research Institute.

The International Council of Ophthalmology is honoring Dr. Mark O. M. Tso for his effort in international ophthalmic education by naming the ICO Mark Tso Golden Apple Award in his honor. Golden Apple Awards have been given since 2002 for outstanding educators of clinical ophthalmology in four continents represented by the Pan American Ophthalmic Association (PAOA), the Asia Pacific Academy of Ophthalmology (APAO), the European Society of Ophthalmology (SOE), the Middle East Africa Council of Ophthalmology (MEACO). Dr. Tso has been the Vice President of the International Council of Ophthalmology Dr. Mark O.M. Tso in charge of Ophthalmic Education for eight years (2000-2008) and served additionally as the Director for Education for four years (2008-2012). Development 410-955-2020 Appointments 410-955-5080 15 annual review Faculty Feats Diana V. Do, MD ■ A sampling of FY12 honors for Wilmer physicians Invited faculty member at the Macula 2012 Congress, NY ■ Delivered the 2012 Albert D. Frost Esen Karamursel Akpek, MD Memorial Lecture at the 55th Annual Post-graduate Symposium, Havener ■ Awarded Jerome L. Greene Foundation Eye Institute, Ohio State University Discovery Fund to study dry eye in ■ Served as program chair, the 2012 Maryland patients with Sjogren’s Syndrome Society of Eye Physicians and Surgeons 5th ■ Appointed Cornea Society representa- Annual Ophthalmology Convention tive to the Cornea External Disease Pre- ferred Practice Patterns Panel supported by American Academy of Ophthalmol- Elia Duh, MD ogy ■ Awarded R01 grant from the National ■ Delivered the 2011 Kayes Professorship Lecture, Eye Institute to study the “Regulation Washington University, St. Louis, MO of Diabetic Retinopathy by Nrf2” ■ Attended the Lasker/International Retinal Neil Bressler, MD Research Foundation Initiative in Dia- betic Retinopathy conferences in Woods ■ Elected President-elect of the Macula Hole, MA, and the Howard Hughes Society, one of the leading societies of Medical Institute’s Janelia Farm Research Campus retina specialists in the world ■ Appointed an editorial board member of Cell & Bioscience ■ Received a patent for a system and method for automated detection of age-related macular degeneration and Charles Eberhart, MD, PhD other retinal abnormalities—nominated as one of the ■ Inventions of the Year by the Johns Hopkins University Promoted to Professor of Pathology, Applied Physics Laboratory Ophthalmology, and Oncology ■ Invited speaker at 2012 ARVO Ocular ■ Chaired the National Institutes of Health-sponsored Oncology Course, Ft. Lauderdale, FL, Diabetic Retinopathy Clinical Research Network delivering lecture: “Targeting Notch in Uveal Melanoma” ■ Recognized, among other accomplishments in 2012, as having the most cited article since 2007 in Ophthalmology, ■ Served as visiting professor, Uniformed Services Univer- the journal of the American Academy of Ophthalmology sity of Health Sciences, Department of Ophthalmology, “Pathology and genetics of optic nerve lesions” Susan Bressler, MD ■ Completed several-year responsibility David S. Friedman, MD, MPH, PhD serving on the NIH-sponsored Data ■ Recipient of Alcon Research Institute and Safety Monitoring Committee Award ($100,000), given to six eye of the CATT study, the critical trial health researchers worldwide comparing Lucentis and Avastin for individuals with neovascular AMD ■ Awarded funding by the Centers for

■ Disease Control to continue research Concluded service to the NIH-spon- into public health approaches to sored Diabetes Clinical Research Network (CRCR.net) blindness prevention in underserved populations in the as a vice chair, but continued in manuscript develop- United States ment role for the network ■ ■ As the newly appointed director of the Dana Center Served as Retina Section Chair for the International he was invited to speak at major meetings in Canada, Controversies in Ophthalmology Meeting in Istanbul, Germany, England, India, China, and Turkey attended by 800 participants and continuing this year in Budapest

16 SightLine FALL 2012 Morton F. Goldberg, MD Barbara S. Hawkins, PhD, FSCT ■ Received the Inaugural Builders of Sight ■ Invited speaker at the 2012 ARVO tribute Clinical Research Award from The Foun- to Carl Kupfer, MD, who directed the dation Fighting Blindness, Inc. National Eye Institute of the NIH for ■ Served as Honorary Chairman, Annual 30 years as the first director Visionary Awards, The Foundation ■ Writing a book with Mandi Conway, Fighting Blindness, Baltimore Chapter MD, with a working title of Clinical Trials in Ophthalmology: A Historical Perspective on Current Clinical Practice Judith E. Goldstein, OD, FAAO ■ Lead author of two chapters of the 5th edition of ■ Awarded a Karl Kahane Foundation Retina (known as Ryan’s Retina) and a co-author of a grant to dedicate resources and third chapter, with publication expected in Fall 2012 equipment for pediatric low vision services at the Wilmer Eye Institute ■ Invited speaker, American Academy Henry D. Jampel, MD, MHS of Optometry, Monroe J. Hirsch ■ Promoted to Deputy Editor-in-Chief of Research Symposium, 2012 the journal Ophthalmology, the highest rated clinical journal in ophthalmology Michael P. Grant, MD, PhD, FACS ■ Invited guest lecturer celebrating 50th Anniversary of the German Society of Albert Jun, MD, PhD Plastic Surgery, Hannover, Germany ■ Named to the editorial board of Cornea, ■ Delivered keynote lecture, Chinese The Journal of the Castroviejo Cornea Society National Eye Meeting, Nanjing, China ■ Developed and published the world’s first ■ International Faculty Member, mouse model of Fuchs Corneal Dystrophy Principles of Mid-Face Reconstruction, AO ■ Awarded a three-year grant from the J. Foundation, Sydney, Australia Willard and Alice S. Marriott Founda- tion for the study of Fuchs Corneal Dystrophy David L. Guyton, MD Richard J. Kolker, MD ■ Delivered the Transamerica Lecture at UCSF Residents Day, March 2012 ■ Authored book on refraction published ■ Delivered the Dan Boyaner Lecture by the American Academy of at McGill University, June 2012 Ophthalmology on the Resident Hub of the ONE Network ■ Delivered the Professor Samuel B. ■ Johnson Memorial Lecture at Invited speaker for the Johns Hopkins University of Mississippi, June 2012 Nurse Practitioner diagnosis course, 2011-2012, and for the JCAHPO 2012 Annual Meeting in Chicago, IL James T. Handa, MD ■ Received RPB Senior Scientist Award Peter J. McDonnell, MD ■ Renewed R01 EY14005 grant ■ Keynote speaker, Yale University Eye ■ Invited speaker at International Society of Center, 2012 Eye Research, Berlin, Germany, July 2012 ■ Delivered the Helen Keller Lecture at the University of Alabama, Birmingham, 2012 ■ Received the Robert L. Murphy Visionary Award, Eye Foundation of America, 2012 more > Development 410-955-2020 Appointments 410-955-5080 17 annual review

Shannath Merbs, MD Josephine O. Owoeye, OD, MPH ■ Invited speaker, FASEB Summer ■ Became a Fellow of the American Conference, “Biology and Chemistry of Academy of Optometry Vision,” Carefree, AZ ■ Received an American Health Assistance Foundation National Glaucoma Research Grant of $100,000 ■ Served as executive secretary, American Society of Ophthalmic Plastic and Reconstructive Surgery Harry Quigley, MD Neil R. Miller, MD ■ Awarded the Neil Miller Medical ■ Delivered the 25th Angelina M. Parks Student Teaching Award, voted on Lecture, Children’s National Medical by Johns Hopkins medical students Center, Washington, DC ■ Delivered the John Lynn Lecture and ■ Delivered the 40th F. Bruce the Royal College of Physicians and Fralick Lecture, Kellogg Eye Center, Surgeons of Canada Lecture University of Michigan Medical Center, ■ Earned five-star reviews on Amazon.com for his book Ann Arbor, MI Glaucoma: What Every Patient Should Know ■ Delivered the third Singapore College of Ophthalmologists Lecture at the 19th International Neuro-Ophthalmology Society Meeting, Singapore

Pradeep Ramulu, MD, PhD Elliott H. Myrowitz, OD, MPH ■ Voted Most Promising Assistant ■ Invited to chair two sessions and give Professor, Wilmer Eye Institute two talks at The World Ophthalmology ■ Visiting Professor, LV Prasad Eye Congress, Abu Dhabi, UAE Institute, India ■ Made three consulting trips to Sarasota, FL, working with the major and minor league teams of the Baltimore Orioles ■ Joined only four other optometrists to be awarded a Diplomate in Refractive Technologies by the American Academy of Optometry’s Cornea, Contact Lenses and Refractive Technologies section Michael X. Repka, MD, MBA ■ Delivered the Frank D. Costenbader Quan Dong Nguyen, MD, MSc Lecture at the annual meeting of the ■ Delivered the William H. Havener American Association for Pediatric Memorial Lecture at the 55th Annual Ophthalmology on Strabismus, entitled Post-graduate Symposium, Havener “Strabismus among Aged Medicare Eye Institute, Ohio State University Beneficiaries” ■ ■ Guest of Honor and Invited Speaker at Completed a three-year term as the 2012 7th Retina-Macula-Vitreous chairman of the Dermatologic and Ophthalmic Hippocratic Meeting, Thessaloniki, Drugs Advisory Committee, FDA Greece; the 2012 Meeting of the Cleveland ■ Appointed Medical Director for Governmental Affairs, Ophthalmological Society; and the 2012 IV American Academy of Ophthalmology Jornadas Oftalmologicas, Caracas, Venezuela ■ Chair of the Multi-Center iDEAL Study for Diabetic Macular Edema sponsored by the Juvenile Diabetes Research Foundation

18 SightLine FALL 2012 Oliver Douglas Schein, MD, MPH Prem S. Subramanian, MD, PhD

■ Appointed Chair, Budget and Finance ■ Appointed Section Editor of the British Committee, Johns Hopkins Medicine Journal of Ophthalmology Clinical Practice Association ■ Elected to Board of Directors, North ■ Delivered the Irving Leopold American Neuro-Ophthalmology Lecture at the Mount Sinai School Society of Medicine; guest speaker, French ■ Visiting professor, Great Lakes Neuro- Ophthalmologic Society, Paris; visiting professor, Ophthalmology Congress Storm Eye Institute, Medical University of South Carolina; and keynote speaker, New York Laser and Surgical Society ■ “Top Doctor” recognition nationally and locally in Jennifer E. Thorne, MD, PhD Baltimore Magazine ■ Invited to sabbatical at the University of Paris IV, summer 2012 Hendrik P. N. Scholl, MD, MA ■ Elected Vice Chair, Fellowship Review Committee, AUPO Fellowship Com- ■ Testified at the House of Representa- pliance Committee, Board of Managers tives Hearing representing the National ■ Invited teacher/lecturer to Cambodia Alliance for Eye and Vision Research on behalf of the International Ocular ■ Assumed coordination and position Inflammation Society of Principal Investigator of the multi- center natural history study of the progression of atrophy secondary to Stargardt’s Disease (ProgSTAR study) funded by the National Neurovision Mark O. M. Tso, MD, DSc Research Institute (NNRI) at Foundation Fighting ■ Honored with an award in his name: Blindness (FFB) “International Council of Ophthalmol- ■ Appointed by the Food and Drug Administration to ogy Mark Tso Golden Apple Awards serve as consultant on the Ophthalmic Devices Panel of for the Best Clinical Educator of the Medical Devices Advisory Committee Ophthalmology in Four Continents”

Richard D. Semba, MD, MPH ■ Authored a new book, The Vitamin A David Zee, MD Story (Karger, August 2012) ■ Published in Roberts et al. Current ■ Co-authored another book, A Perfect Biology, 2011 Vision, to be published by Ascensius ■ Dicovered a new technique to study Press, Fall 2012 how the brain processes information ■ Awarded two new investigator-initiated when the eyes are jerking involuntarily grants from the National Institutes of Health and to try to develop ways to stop them ■ Delivered the Lord Adrian Lecture at Cambridge University, England; the Michael Sanders Lecture in Walter J. Stark, MD London; and the Irwin Levy lecture at the University of Washington, St. Louis ■ Guest of honor, Mount Sinai School of Medicine ■ Principal investigator at Wilmer for the Corneal Preservation Time Study ■ Served as course director of the Wilmer Current Concepts meeting in Baltimore, MD, and Vail, CO Development 410-955-2020 Appointments 410-955-5080 19 annual review

Our Work to Cure Blindness: Our Donors The scientists and staff of the Wilmer Eye Institute at Johns Hopkins gratefully acknowledge our partners in philanthropy listed here. The generosity of these friends supports a tradition of collaboration and far-reaching investigation as, together, we pursue the complex challenges of eye diseases. While our space here is limited, our thankfulness is not. Although gifts of any amount are gratefully received, only gifts, pledges, and pledge payments totaling more than $250 in the fiscal year ending June 30, 2012, could be listed in this report. If any donor was accidentally missed, or if you prefer to remain anonymous, please contact the Development Office at 410-955-2020.

Mr. Robert J. Abernethy Baltimore Host Lions Club Mrs. Rebecca A. Buzzard Ms. Rusconi Vincenzina Contini Mr. David S. Abrams The Bank of America Foundation Ms. Betsy F. Cadden Ms. Laura A. Corazza Abraham Krasne Foundation Mr. Melvin Barmat* The Anne D. and Charles A. Dr. Gabriel Coscas Acell Incorporated Mr. Peter A. Barna Camalier Jr. Family Foundation Ms. Theresa A. Coscia Dr. Jan P. Acton Mrs. Priscilla F. Barrett Brig. Gen. and Mrs. Thomas Claude L. Cowan Jr., MD Olivia Demetriou Adamstein, Theodore H. Barth Foundation, Inc. J. Camp Jr. Crisfield Lioness Club FAIA Mr. and Mrs. R. Bruce Bass Mr. Arthur A. Campbell William E. Cross Foundation, Inc. Ms. Marilyn Adelson Ms. Catherine Beal The Capital Group Charitable Ms. Hallie D. Crowell* Akebia Therapeutics John D. Beal, DDS Foundation Cure for Blindness Inc.G Alcon Laboratories, Inc.W The Beaufort Foundation Caplan Family Foundation, Inc. Mr. Alan J. Dabbiere Alcon Research InstituteG Arnold and Mabel Beckman Mrs. Carol J. Carlson Gislin Dagnelie, PhD Mr. Benjamin Alexander Foundation Mr. Leland V. Carlson Darlington Lions Club, Inc David B. Allison, PhD Miss Constance D. Bendann*B Mr. and Mrs. J. Thomas Mrs. Lynn R. Davidov Altsheler-Durell Foundation Bender Foundation, Inc. Carruthers Jr. John and Cora Davis Foundation American Geriatrics SocietyG Mr. James J. Bergera Mr. John J. Cassidy Ms. Montserrat Simo De Vilar American Glaucoma SocietyG Ms. Lori C. Berhent Mr. Michael Cataneo Dealy Foundation, Inc. American Health Assistance The Berner Charitable and Caterpillar Foundation Mr. John J. Delaney FoundationG Scholarship Foundation Cecilton Lions Charities, Inc. Mr. and Mrs. Robert G. Depew Mr. and Mrs. Peter C. Andrews The Honorable Stuart A. Mr. and Mrs. Philip B. Cerveny Mr. Conrad J. Derdeyn Anonymous (6) Bernstein Ms. Yvonne B. Chanatry Mr. and Mrs. John C. Detweiler Arizona Odd Fellow-Rebekah Mr. Denny Bertolla and Mr. Paul Cheshire Mr. and Mrs. William O. DeWitt Jr. Visual Research Foundation Ms. Mary E. Blackman Mr. and Mrs. Clement Chen III Diabetes Research and Wellness Arthritis FoundationG Ms. Donna W. Blake and The Francis and Miranda FoundationG Mr. Roland S. Arthur Mr. Bruce E. Eckstein Childress Foundation Ms. Mary Jane Dimartino Mr. and Mrs. Conrad Aschenbach Paul S. Bomberger Jr. Timothy Y. Chou, MD Doheny Eye InstituteG Ms. Lila Oliver Asher Foundation, Inc. Judith F. Chused, MD, PC Mr. and Mrs. Steven Dola Mr. and Mrs. Norman J. Asher Anna Borun and Harry Cinkala Family Fund The Honorable Elizabeth H. Dole Mr. and Mrs. Alan Astrove Borun Foundation Mrs. Rose Cipriano Mr. William A. Donlon Mrs. Virginia C. Atkinson Mrs. Ann A. Bosworth The Honorable Richard C. Clark Mr. William J. Dorman Jr. The Phyllis L. and Leonard J. Mr. and Mrs. Michel M. Mr. A. James ClarkW Mr. and Mrs. Kevin Dorsey Attman Foundation, Inc. Boxberger Clark Charitable Foundation George and Grace Dragas Mr. Martin Auerbach Mr. and Mrs. John Brennan Jr. Mr. Harris Clay Foundation Dr. and Mrs. Alex Azar Drs. Neil M. and Susan B. Bressler Mr. Harold E. Clendenin Mr. and Mrs. John A. Driggs BAE Systems Employee Ms. Paula J. Brooks Mr. Carl C. Coe Jr. Elizabeth and Richard Dubin Community Fund, Inc. Mr. and Mrs. Fitzhugh L. Brown Ms. Bettye F. Coil Foundation Mr. Goutam Bagchi Mr. and Mrs. Howard Mr. William K. Colbath Mrs. Jean H. Durfee Mr. Robert R. Bair N. Brownstein Mr. Edward Colburn Mr. Matt E. Egger William A. Baker, MD Ms. Elizabeth J. Bruen George E. Coleman Jr. John E. Eisenlohr, MD Mr. and Mrs. Richard P. Baks Burlingame Foundation Foundation El Sawy Family Foundation Ms. Jamie L. Baldinger Edward N. Burney, MD Mr. and Mrs. Ronald E. Collins Dr. and Mrs. Haskell S. Ellison Edmund F. and Virginia B. Ball Ms. Betty J. Burr Community Family Care IPA Geri Emalfarb, LTD FoundationW Mr. and Mrs. Arthur Buslik Mrs. Jo Ann Condry Mr. Norio B. Endo Mr. Glen H. Ballowe Mr. Michael F. Butler Ms. Nancy A. Conte Ms. Maria Teresa Escalante

20 SightLine FALL 2012 Mr. and Mrs. David Esses Mr. Wilbert Graybeal* Mr. Roger Irvine Mr. and Mrs. Scott Lederman ExxonMobil Foundation Mrs. Janet J. Green Adam Jacobowitz, MD Mr. and Mrs. Jung Lee Eye Bank Association of AmericaG Mr. Milton D. Greenbaum Mr. and Mrs. Benjamin R. Jacobs Mr. and Mrs. L. Douglas Lee Eye Foundation of America Mrs. Monica L. Greenberg Mr. David A. James Mrs. Elise G. Lefkowitz The Eye Research Fund Mrs. Shirley K. Griffin Ms. Nancee James Mr. Richard Lehmann and Rear Adm. John N. Faigle Ms. Lia Grigoras Dr. Tariq Jamil Ms. Kathleen Anne Feely Dr. Charles Farquhar Mrs. Leith S. Griswold Jampel Family Foundation Mr. David T. LeightonB Mr. and Mrs. David E. Feldman The Grodzins Fund Mrs. Ellenor B. Jarrett George A. Lentz Jr., MD Mr. Robert P. Feldman Louis H. Gross Foundation, Inc. William H. Jarrett II, MD Mr. Matthew Lerzak Mrs. Barbara F. Fenton Emanuel Gruss and Riane Gruss Jarrettsville Lions Club Ruth Baldauf Levi and Richard Mr. and Mrs. William A. Charitable Foundation Mrs Beverly B. Jennings A. Levi Charitable Foundation Ferguson Guerrieri Family Foundation, The Jenny Fund Against Cancer Mr. Ronald Levin Daniel Finkelstein, MD Inc.B Ms. Nancy Johns Mr. and Mrs. Robert M. Levy Mr. Thomas A. Fitzgerald Mr. George M. Guill Jr.* Johns Hopkins Federal Mr. Holmes Liao and Ms. Adrienne A. Flanders and Mr. and Mrs. Alvin Gutterman Credit Union Ms. Hue-Hsiung Cheng Mr. Gerald M. Friedman Mr. Lawrence Habera Johnson & Johnson Services, Inc.G Lifelong Vision Foundation Dr. William F. Flanigan Jr. Mr. and Mrs. Willard HackermanW Mr. and Mrs. James W. Jones Lions Club of Olney, Inc. Ms. Mary D. Flournoy Mr. Jacques G. Hager Mr. and Mrs. Palmer S. Jones Lions Vision Research Mr. George R. Floyd Amin M. Hanafy, DSc Ms. Virginia M. Jordan Foundation, Inc.B Mr. Dennis J. Flynn Dr. Ingeborg Hanbauer-Costa Dr. and Mrs. Jau-Shi Jun Lord Baltimore Lions Charities Mr. and Mrs. Jack Flynn Dr. James Handa Mr. and Mrs. Joshua I. Justin Mrs. Katherine M. Loughlin Mr. William T. ForresterW Michael J. Harris, MD Juvenile Diabetes FoundationG Mr. Leonard Loventhal and Mr. and Mrs. Richard A. Mrs. Rebecca D. Harris Karl Kahane Foundation Celerina Mrs. Renee V. Loventhal ForsytheB Mr. Stuart M. Harrison Mr. and Mrs. Wolf Kahn Mr. Peter Luchsinger The Foundation Fighting Mr. and Mrs. Robert L. Mr. Martin L. Kamerow Mr. Robert G. Luedke BlindnessG Harteveldt Kane Lodge Foundation, Inc. Mr. Theodore C. Lutz Robert N. Frank, MD Hartwell FoundationG Mr. Marshall V. Kaplan Drs. Mary G. Lynch and Reay Mr. Edward Franz Ms. Kristie Hassett Mr. and Mrs. Randall Kappesser H. Brown Mr. Morris Freedman Howard and Martha Head Fund, Inc. Mr. and Mrs. Allen Kayne Ms. Hazel M. Lyon Ms. Barbara W. Freeman Health Resources in ActionG W. M. Keck Foundation Mrs. Josephine B. Lyons Mr. Ernest Freudman Roberta W. Heath, BSN, MSN, MBA Ms. Diane L. Kemker Ms. Alice Ma Russell I. Fries, PhD Ms. Alison Heilman Ms. Joan F. Kennedy and Mr. and Mrs. Patrick Madden William F. Fritz, MD Mr. Franz A. Heinsen and Mrs. Frances E. G. Kennedy Mr. and Mrs. Preston Madden Mr. Victor Gallo Alycia J. Bartley-Heinsen, MD Mr. and Mrs. John B. Kentch Mr. Thomas Mammarella and Bill and Melinda Gates Helen Keller InternationalG Drs. Jeong H. and Cynthia Mrs. Barbara A. Marsh FoundationG Leona and Harry Helmsley H. KimW Ms. Linda Manglass Ms. Anna M. Geary Charitable TrustG Ronald M. Kingsley, MD Mr. Andrew Marriott Mrs. Janet C. GehrleinW Mr. and Mrs. Avi Hershkovitz Clarence W. and Ida W. Klassen The J. Willard and Alice S. Genentech, IncorporatedG Mrs. Joan M. Hewitt Charitable Foundation Marriott Foundation Mrs. Esther A. Gerber Ms. Elaine K. Hill* Ms. Susan A. Kline Ms. Kelsey Marshall Carl and Nancy Gewirz Fund The Hills Family Fund Malcolm R. Knapp, PhD Bennett and Dobra Marshall Bernard and Sarah Gewirz Hobbs Family Charitable Trust Knights Templar Eye Family Fund Foundation Dr. and Mrs. Joseph G. Hoeg FoundationG Mr. and Mrs. M. Lee Marston Mrs. Laura S. Gibian Mr. and Mrs. F. William Mrs. Marlene Koeppel Maryland Society Southern Dr. and Mrs. James P. Gills Jr.B Hoffman Fred S. and Celia Kogod Dames of America Ms. Martha Gil-Montero Mr. David L. Holman, CPA Foundation, Inc. Ms. Jean Mattison Mr. James H. GipsonB Mr. and Mrs. Alan R. Hopkins Mr. Shameek Konar Mr. and Mrs. L. Stanley Mauger Gitter and Yelen Foundation Mr. Lawrence A. Horn Saranne and Livingston Kosberg William May, MD Ms. Beth Glassman Mr. Antoni Horodowicz Ms. Sharon A. Kress Mr. Bernard D. Mayer Jr. Glaucoma Research FoundationG Mr. James A. Hourihan Mr. and Mrs. Robert D. Kunisch Sr. Mrs. Beatrice C. Mayer GlaxoSmithKline FoundationG Mr. Steve Hronec Mr. and Mrs. Raymond P. L. Ms. Camilla McCaslin Mr. and Mrs. Jeffrey Goldberg Drs. Suber S. and Cynthia P. KwokW Mr. Hugh P. McCormick Jr. Dr. and Mrs. Morton F. Goldberg Huang Dr. and Mrs. Chul S. Kwon Goldman Sachs & Co. Mr. Harvey L. Hudson Jr.* Mrs. Darlene V. LaChappelleW * Deceased Mr. and Mrs. Jack Golin The Hultquist Foundation Dr. Adewale A. O. Laditan G Grants Mrs. Virginia F. Gomprecht Mrs. Mary S. Humelsine Dr. and Mrs. William H. Lake B Breckenridge Lifetime Giving Mr. and Mrs. C. Michael Gooden Mr. Craig B. Huston*B The Oliver and Elizabeth Laster Society Gordon Foundation Mr. Christopher Ihde Foundation W William Holland Wilmer Mr. and Mrs. Nicholas Gounaris Dr. Helen J. IliffW Lavery Foundation Lifetime Giving Society Mrs. Florence Hill Graff ImClone Systems IncorporatedG Mrs. Kathleen M. Lawrence Development 410-955-2020 Appointments 410-955-5080 21 Mr. James C. McCrery The Ort Family H. Rubenstein Family Charitable Dr. and Mrs. John T. Thompson Mrs. Cheryl McCullen Philanthropic FundW Foundation Mr. W. Reid Thompson Mr. and Mrs. James Mr. Gregory Otto Ms. Ann H. Ruppe Mr. Stephen M. Thorpe P. McDonagh Mr. Florenz R. Ourisman Mr. John J. Ryan III Mr. and Mrs. William R. TiefelW Capt. and Mrs. William M. Ms. Kathryn L. Oursler Ms. Mary Lou Ryce Mrs. R. Carmichael Tilghman* McDonald, USN, Ret William and Ella Owens Medical Ms. Susan A. Safer Ms. Mary D. Tillery Drs. Peter J. and Jan M. Research Foundation Dr. and Mrs. Surajit Saha Mr. Philip Trainer McDonnell Dr. and Mrs. Ray T. Oyakawa Mr. Alfonso Saia Mr. Danh Tran Ms. Jeannette J. McGann Dr. and Mrs. Lawrence C. Pakula Salisbury Wicomico Lions Club Mr. and Mrs. Norman Tunkel Mr. John J. McGann Mr. and Mrs. Peter Parapiglia Mrs. Poonam Salona Mr. Albert W. TurnerB Mr. Daniel E. McLain Ms. Rose Parapiglia Mrs. Elaine L. Sargent Mr. Adam Turoff Mr. and Mrs. Bart A. McLean Saurabh N. Patel, MD, MsC R & Z Sass Family Foundation Mr. and Mrs. Thomas E. Utz Mr. David S. McLean David Paton, MD Milton Schamach Mr. and Mrs. Steve X. Vagnerini Mr. John K. McNulty Jr. Ellen L. Patz Philanthropic Fund Foundation, Inc. Veterans of Foreign Wars Mr. and Mrs. John K. McNulty Sr. Mr. Michael L. Peck Ms. Robin E. Scheiderman Post 219 Mr. and Mrs. William McSweeny Mr. Paul L. Peck Jr. Mrs. Carolyn S. Schlenger Mr. David W. Wallace Mr. and Mrs. Robert T. Dr. and Mrs. George L. Perry Mr. and Mrs. Gabriel Schmergel Mr. and Mrs. Stratford McWhinney Jr. Dr. Gholam Peyman Mrs. Tamara T. Schnydman C. Wallace The Merck Company Foundation Dr. and Mrs. Paul Peyser Mr. Arnold R. Schunick Mr. Mark E. Wallen Kenneth A. and Jo A. Merlau James R. Phippard Foundation Daniel M. Schwartz, MD Mr. and Mrs. James H. Wallwork Fund Plave Koch PLC Miss Dorothy M. Scott* Clarence D. Ward Trust Mr. W. Mark Meyers Mr. Rubin Plushner Ms. Jean P. Sehlhorst Mr. and Mrs. Peter A. Warner Dr. and Mrs. Albert T. Milauskas Ms. Roberta M. Polk Dr. Hollis Seunarine Mr. Frank Was Ms. Judith A. Miller Dr. and Mrs. Irvin P. Pollack Jacob S. Shapiro Foundation The Washington Post Company Mrs. Anne Miller Ms. Naomi L. Pollard Mr. and Mrs. David F. Sheaffer Mr. Edward H. Welbourn III Mr. and Mrs. Rodney E. Milnes Mr. and Mrs. Charles R. Poppe Mr. James D. Shockey Dr. and Mrs. Robert B. WelchW Mr. Arthur R. Minner Promedior, Inc. Dr. and Mrs. Richard Mr. John B. Wheeler Miriam Lodge K.S.B., Inc. Ms. Jennifer B. Quartner G. Shugarman Wiley, Rein, LLP John Mitchell Jr. Trust Dr. and Mrs. Harry A. Quigley Rose L. Shure Drs. Shelby R. Wilkes and Surya Mohapatra, MD Norman Raab Foundation Mr. and Mrs. Milton L. Shurr*W Jettie M. Burnett Mr. Daniel Molerio Mr. M. Robert Rappaport Mr. Lee M. Silverman Charles P. Wilkinson, MD Mr. Allan S. Moller Ms. Barbara Raso Mr. Jerrald K. Simmers Ms. Barbara J. Williams and Richard J. Moriarty Mrs. Mary Jane B. Read Mr. Jon B. Singer Mr. Cliff Madrack Charitable Fund Mrs. Marilyn S. Reiner Capt. and Mrs. Frank L. Smith Mrs. Gertrude J. Williams Mr. John S. Morton Jr.* Michael X. Repka, MD USN Ret. Ms. Gertrude S. Williams Samuel and Margaret Mr. John P. Requa Robert H. Smith Family Mr. and Mrs. Franklin K. Wills Mosher FoundationW Research to Prevent BlindnessG FoundationB Mr. Lon P. Wilson Ms. Dorothy M. Mudd Mr. and Mrs. Timothy N. Resler Society for Clinical Trials, Inc. Mr. Arthur S. Wolcott Mr. Ed Nachazel Retinal Vascular Foundation Alfred Sommer, MD, MHS Mr. Donald R. Wolfe National Neurovision Dr. and Mrs. Charles B. Reuland Dr. Valery N. Soyfer Ms. Molly P. Wolfe Research InstituteG Ms. Diana Rezaee The Girardeau A. Spann Ms. Marcella E. Woll* Ms. Francine Neall Mr. Peter Riddleberger Charitable Fund Mr. and Mrs. James R. Wood Ms. Cathy A. Nelson Mr. Eric C. Riedinger Mr. Kenneth D. Spell William J. Wood, MD Mrs. Jane R. Nelson Mr. Maxcy C. Rivkin Mr. Jerry I. Speyer and Ms. Aleda C. Wright Mr. Philip Niarchos Mr. Kenneth Roberts Ms. Katherine G. Farley Mr. and Mrs. Bernard J. Young Mr. Richard A. Nielsen Mr. Carl Roberts Dr. Charles H. Spragg Mr. and Mrs. A. Thomas Young Mrs. Agnes E. NixonW Mrs. Mary Jane Roberts Mr. Laurence A. Stappler Ms. Florence M. Young Mr. James P. Nolan Jr. Mr. Brooks C. Robinson Mrs. Lina A. Steele Mr. William T. Young Jr. Dr. and Mrs. Michael A. Novak Mrs. Maureen A. Robinson Mr. and Mrs. William R. Stewart Mr. John F. Younkman Mr. and Mrs. Lawrence C. Mr. Jean M. Rogers Ms. Dorothy L. Stineman* David S. Zee, MD Nussdorf Ms. Shelly Rogers Mrs. Betsy B. Stires Mr. and Mrs. Stephen Zilliacus Mr. Ralph S. O'Connor David A. Rosen, MD Rebecca A. and Bradley A. Ingrid E. Zimmer-Galler, MD Odd Fellows and Rebekahs Visual Henry and Ruth Blaustein Stirn Fund Mr. and Mrs. Joseph C. Zuray Research FoundationW Rosenberg Foundation Ms. Nanette L. Stoffan Mr. David Oestreicher Mr. Eugene T. Rossides Leon Strauss, MD, PhD * Deceased Mrs. Shirley Offit Rothkopf Charitable Fund Strouse Family Fund G Grants Dorothea McAnulty Olsen Louise Sloan Rowland Charitable Subramanian Family Fund B Breckenridge Lifetime Giving Foundation Fund Suburban Lions Club, Inc. Society Ms. Maria Orellano Ms. Mona Rubenfeld-Sarid Ms. Joan B. Sullivan W William Holland Wilmer Dr. and Mrs. Richard J. Thomas Lifetime Giving Society 22 SightLine FALL 2012 Development 410-955-2020 Appointments 410-955-5080 23 Non-profit Org. SightLine U.S. Postage Paid Baltimore, MD SightLine is published twice a year by the Wilmer Eye Institute at Johns Hopkins. Permit No. 2589 Managing Editor: Mary Anne Davis Editor: Sue De Pasquale Contributing Writer: Marlene England Designer: Abby Ferretti © 2012 The Johns Hopkins University and The Johns Hopkins Health System Corporation To add/remove/update your name from the mailing list, please send your name and address to: The Wilmer Eye Institute Sightline Subscription 600 N. Wolfe Street, Wilmer 112 Baltimore, MD 21287-9015 [email protected] 410-955-2020 410-955-0866 (fax)

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