Authors: Pallavi Subhraveti Ron Caspi Peter Midford Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_003718175Cyc: Salmonella enterica enterica servovar Typhi str. 311189_255186 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari

cefoperazone cefoperazone cefoperazone D-methionine glucosyl-oleandomycin glucosyl-oleandomycin glucosyl-oleandomycin met

RS01265 RS11510 RS24335 RS05735

cefoperazone cefoperazone cefoperazone D-methionine glucosyl-oleandomycin glucosyl-oleandomycin glucosyl-oleandomycin met

Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis Aminoacyl-tRNA Charging Macromolecule Modification queuosine biosynthesis γ 2604 32 cob(II)alamin- a peptidoglycan ditrans,octacis- a (2R)-2-hydroxy ditrans,octacis- ditrans,octacis- a peptidoglycan L-alanyl- -D- a 23S rRNA 3-(all-trans- a uridine a uridine 3-oxo-2-(cis- (S)-1-pyrroline- an oxidized a protein Aromatic Compound Biosynthesis Carbohydrate Degradation (S)-mandelate (R)-glycerate cob(II)yrinate a,c- tRNA charging Entner-Doudoroff pathway I methylmalonyl- with (L-alanyl- undecaprenyldiphospho- even numbered cob(II)yrinate undecaprenyldiphospho- undecaprenyldiphospho- UDP-N-acetyl- glutamyl-meso-2,6- uridine 1911/1915/1917 nonaprenyl) in 23S rRNA in tRNA 2'-pentenyl)- 5-carboxylate nitroaromatic with incorrect [2Fe-2S] iron-sulfur superpathway of demethylmenaquinol-8 biosynthesis I superpathway of tetrahydrofolate biosynthesis ubiquinol-8 biosynthesis guanylyl molybdenum flavin biosynthesis I (bacteria and plants) siroheme biosynthesis superpathway of pyridoxal 5'-phosphate biosynthesis and salvage adenosylcobalamin 5-methoxybenzimidazolyl L-rhamnose degradation II 2-deoxy-D-ribose ATP [CblC-CblD ATP dimer with biotin ATP diamide biosynthesis I benzimidazolyl adenosylcobamide preQ D-galactose degradation I (Leloir pathway) Aldehyde Degradation CoA mutase γ β straight chain a,c-diamide α-D-muramate benzene-1,2-diol cyclopentane-1- mandelate racemase/ glyoxylate/ trifunctional compound disulfide bonds cluster biosynthesis (prokaryotic) 0 degradation I complex] -D-glutamyl-L- N-acetyl-(N-acetyl- -D- N-acetyl-(N- N-acetyl-(N- pentapeptide diaminopimeloyl- bifunctional tRNA bifunctional 3- bifunctional tRNA bifunctional tRNA oxygen-insensitive thiol:disulfide cofactor biosynthesis salvage from cobalamin adenosylcobamide biosynthesis biosynthesis from NADPH-dependent 7- D-glucopyranose UDP-N- hydroxypyruvate (early cobalt insertion) D-erythrose enterobactin biosynthesis cob(I)yrinic acid lysyl-D-alanyl- glucosaminyl)muramoyl- 2,3,4-saturatedlong-chain-fatty- cob(I)yrinic acid acetylglucosaminyl) acetylglucosaminyl) stems (meso- D-alanine pseudouridine(32) demethylubiquinone 3- pseudouridine(32) pseudouridine(32) (3-oxohexanoyl) muconate lactonizing transcriptional NAD(P)H interchange bifunctional all-trans- MoO - uroporphyrinogen-III from adenosylcobinamide-GDP adenosylcobinamide-GDP arg 4-hydroxyphenylpyruvate cyano-7-deazaguanine 6-phosphate β L-rhamnopyranose peptidoglycan acetylmuramate:L- acetyl-CoA C- chorismate 2 -D-galactopyranose 2-deoxy-D-ribose methylglyoxal degradation I a,c-diamide D-alanine) L-alanyl-γ-D-glutamyl-L- fatty acid a,c-diamide muramoyl-L-alanyl-γ- muramoyl-L-alanyl- N-acetylmuramoyl- synthase/ribosomal synthase/ribosomal synthase/ribosomal -CoA enzyme family protein: reductase A: regulator/proline biotin-- uroporphyrinogen-III L-cysteine desulfurase GTP 4-hydroxybenzoate octaprenyl GTP 4-phosphate cob(I)alamin arginine--tRNA ligase: L-lactaldehyde acid--CoA ligase: diaminopimelate O-methyltransferase/2- acyltransferase nitroreductase: protein molybdopterin siroheme 5-methoxybenzimidazole biosynthesis reductase QueF: queF adenosyltransferase: glycosyltransferase adenosyltransferase: β γ L-alanine alanyl-gamma-D- SM255186_RS19485 SM255186_RS05625 dehydrogenase/L- siroheme benzimidazole SM255186_RS10000 pentapeptide lysyl-D-alanyl-D-alanine SM255186_RS09530 D-isoglutaminyl-N-( - -D-isoglutaminyl- containing) large subunit octaprenyl-6-hydroxy large subunit large subunit SM255186_RS02970 DsbG: dsbG [acetyl-CoA- isochorismate 4-hydroxybenzoatediphosphate cofactor molybdenum cofactor synthase: cobA D-erythrose- nicotinate-nucleotide-- an L-arginyl- chorismate preQ galactose-1- degradation (anaerobic) FtsI: ftsI glutamyl- meso- FadI: fadI nicotinate-nucleotide-- 1 cobO SM255186_RS10790 D-asparaginyl)-L-lysyl- N-(β-D-asparaginyl) amidase pseudouridine pseudouridine pseudouridine glutamate gamma- carboxylase] synthase: cysteine desulfurase: GTP octaprenyltransferase: 4-phosphate [tRNA Arg ] epimerase: methylglyoxal acyl-CoA peptidoglycan peptidoglycan phenol methylase: mandelate racemase/ bifunctional NAD(P)H bifunctional synthase guanylyltransferase: uroporphyrinogen-III dimethylbenzimidazole dimethylbenzimidazole tyr L-rhamnofuranose 2-deoxy-D-ribose peptidoglycan AmiB:a peptidoglycan amiB diaminopimelate synthase RluA: rluA synthase RluA: rluA synthase RluA: rluA acetyl-CoA C- semialdehyde cobA SM255186_RS08585 GTP cyclohydrolase a tRNA Arg isochorismate tRNA guanosine(34) 6-phospho galM (S)-lactaldehyde cob(I)yrinic acid synthetase cob(I)yrinic acid D-alanyl-D-alanineglycosyltransferase -L-lysyl-D-alanineglycosyltransferase 2-methoxy- SM255186_RS12005 muconate lactonizing glyoxylate/ protein-disulfide ligase/biotin EntC: entC cyclohydrolase SM255186_RS22050 mobA C-methyltransferase: dehydrogenase: cob(II)alamin phosphoribosyltransferase: aromatic amino 5-phosphate lactoylglutathione lyase: a peptidoglycan a (R)-2-hydroxy L-alanyl-γ-D- dimer with UDP-N-acetylmuramoyl-ligase: mpl acyltransferase dehydrogenase: nitroreductase: 3-octaprenyl-4- II: ribA phosphoribosyltransferase: synthase transglycosylase Tgt: D-glucono- a,c-diamide glycosyltransferase a,c-diamide FtsI: ftsI FtsI: ftsI [+ 3 isozymes] ribosomal large ribosomal large ribosomal large 3-oxo-2-(cis- enzyme family protein: hydroxypyruvate operon uroporphyrinogen-III cysteine isochorismate I FolE: folE SM255186_RS15755 cobT α SM255186_RS08265 lactaldehyde with (L-alanyl- FdrA:even fdrA numbered glutamyl-meso-2,6- pentapeptide L-alanyl-γ-D- 6-(all-trans- FadA: fadA a reducedSM255186_RS08935 isomerase/ hydroxybenzoate molybdopterin- SM255186_RS17730 cobT EntC: entC acid transaminase: 1,5-lactone -D-galactopyranose deoxyribose- adenosyltransferase: di-trans,octa-cisFtsI: ftsI adenosyltransferase: subunit pseudouridine 2'-pentenyl)- SM255186_RS11990 reductase B: ghrB SM255186_RS05555 repressor C-methyltransferase: desulfurase 7,8- 2,5-diamino-6-(5-phospho-D- 4-phospho- cob(I)yrinic acid 5-methoxybenzimidazole 3-(4- SM255186_RS02095 (R)-S- reductase: fucO γ-D-glutamyl-L- diphosphate straight chain peptidoglycan peptidoglycan diaminopimeloyl- stem (meso- glutamyl-meso-2,6- subunit pseudouridine nonaprenyl)phenol subunit pseudouridine acetyl-CoA nitroaromatic oxidoreductase synthase UbiD family guanine dinucleotide precorrin-1 benzimidazole ribotide phosphate SM255186_RS22120 phosphate aldolase: a [cobalamin SM255186_RS10790adenosylcobalamin- AMP cobO BirA: birA SM255186_RS17730 CsdA: csdA dihydroneopterin ribosylamino)pyrimidin-4(3H)-one a,c-diamide ribotide phosphate isochorismate a 7-aminomethyl-7- 6-phosphogluconolactonase: lactoylglutathione lactaldehyde reductase: -undecaprenyl di-trans,octa-cis glycosyltransferase di-trans,octa-cis a glycosyltransferasepeptidoglycan synthase D: synthase D: synthase D: cyclopentane- (R)-mandelate hydroxypyruvate DsbC: dsbC MenF: menF biosynthesis protein B: D-erythronate hydroxyphenyl) galactokinase: L-rhamnono- SM255186_RS24550 a [cyanocobalamin lysyl-D-alanyl- 2,3,4-saturated adenosyl-cob(III) a peptidoglycan D-alanyl-D-alanine diaminopimelate diaminopimeloyl- glu compound a protein biotinyl-5'- decarboxylase: synthase 34 trafficking triphosphate [methylmalonyl- diphosphate triphosphate -undecaprenyl -undecaprenyl dimer (E. faecium SM255186_RS13825 1-butanoyl-CoA precorrin-1 3'-triphosphate bifunctional uroporphyrinogen-III adenosyltransferase: cysteine- pyruvate deazaguanosine in tRNA SM255186_RS03940 glycogen degradation II hydroxyacylglutathione SM255186_RS15155 reductase CblC] D-alanine) fatty acyl CoA yrinate a,c-diamide dimerFtsI: (E. ftsI faeciums) FtsI: ftsI containing) D-alanine SM255186_RS13825 SM255186_RS13825 adenylate an S-sulfanyl-[L- SM255186_RS14830 guanylyl SM255186_RS19155 erythronate- adenosylcobinamide- adenosylcobinamide- SM255186_RS03885 1,4-lactone (S)-propane- protein CblD] CoA mutase] a pseudouridine 1911/ a pseudouridine 2604 a pseudouridine 32 with correct isochorismate dihydroneopterin diaminohydroxyphosphoribosylaminopyrimidine C-methyltransferase: cobO -tRNA MenF: menF acetaldehyde hydrolase: diphosphate diphosphate , tetrapeptide) cysteine desulfurase] molybdenum 4-phosphate GDP GDP ribazoletransferase: cys tRNA preQ1(34) S- D-gluconate 1,2-diol pentapeptide disulfide bonds uroporphyrinogen-III triphosphate 4-hydroxy-3- α SM255186_RS01340 1915/1917 in 23S rRNA in 23S rRNA in tRNA cofactor deaminase/5-amino-6-(5-phosphoribosylamino) SM255186_RS17730 dehydrogenase: cob(I)yrinic acid ribazoletransferase: ligase: adenosylmethionine 6-phosphate -D-galactose C-methyltransferase: 2-succinyl-6-hydroxy- diphosphatase: polyprenylbenzoate SM255186_RS10625 isochorismate UDP-α-D-glucose a glycogen uracil reductase RibD: ribD SM255186_RS12500 a,c-diamide SM255186_RS10625 cysS an L-cysteinyl- ribosyltransferase- 1-phosphate SM255186_RS17730 2, 4-cyclohexadiene-1- SM255186_RS09955 decarboxylase: precorrin-2 Coα-[α-(benzimidazolyl)]-Coβ- phosphogluconate ribose phosphorylation (R)-lactate α α Cys glycogen a 2-methyl 3-[(3aS,4S,5R,7aS)-5- 2605 3-oxo-2-(cis- 5-amino-6-(5-phospho- adenosyltransferase: Co -[ -(5- [tRNA ] isochorismatase: isomerase QueA: queA cob(II)alamin- an apo-["base- peptidoglycan D- ditrans,octacis- decaprenyl- 7-carboxy-4-methyl-3,5- uridine 3-oxo-2-(cis- a supercoiled carboxylate synthase: 7,8- SM255186_RS17510 (3R)-3-hydroxy-2-oxo- adenosylcobamide 5'-phosphate Cys dehydratase: edd L-rhamnonate a purine sn-glycerol palmitoyl-CoA H O an L-asparaginyl- (R)-glycerate sn-glycerol precorrin-2 SM255186_RS10790 methoxybenzimidazolyl) a tRNA phosphorylase: branched 2,3,4- a stearoyl-[acp] undecaprenyldiphospho- pyrophosphoryl-(N hydroxy-7a-methyl-1-oxo- 2 2'-pentenyl)- 2'-pentenyl)- an S-sulfanyl-[cysteine dihydroneopterin D-ribosylamino)uracil siroheme 4 phosphooxybutanoate SM255186_RS03065 S-adenosylmethionine:tRNA ATP [CblC-CblD off/His-on" alanyl-DAP crosslink 3-phosphate dioxoheptanoyl-CoA in 23S rRNA [tRNA Asn ] 3-phosphate ITP IMP duplex DNA SM255186_RS12170 β adenosylcobalamin/alpha- SM255186_RS21245 acetyl-CoA β-D-ribopyranose ribonucleoside adenosylcobinamide saturated fatty acid murein DD- octahydro-1H-inden-4- putative acyl-CoA acetyl-CoA C- cyclopentane-1- bifunctional replicative desulfurase]-[disordered- 2-octaprenylphenol bifunctional cob(II)alamin- ]-Co -adenosylcobamide ribosyltransferase-isomerase: Chlorinated complex] B12-enzyme] long-chain-fatty- glycerol-3- N-acetyl-(N- -acetylglucosamine) bifunctional tRNA cyclopentane-1- aminoacyl-tRNA glycerol-3- siroheme 3'-phosphate synthase: cobA 3-phosphoserine/ (2S,3S)-2,3-dihydroxy- KDGP D-ribose pyranase: cob(I)yrinic acid 5'-triphosphate acetyl-CoA C- thioester hydrolase: acyltransferase XTP/dITP diphosphatase: bifunctional UDP- form scaffold 2-succinyl-5- [corrinoid 5'-phosphate ribazole phosphatase: maltodextrin Compound Degradation bifunctional acid--CoA ligase: endopeptidase phosphate acetylglucosaminyl) -N-acetylmuramyl- yl]-3-oxopropanoyl-CoA pseudouridine(32) (3-oxooctanoyl) (3-oxobutanoyl) hydrolase: glyoxylate/ phosphate DNA diaminohydroxyphosphoribosylaminopyrimidine phosphohydroxythreonine 2,3-dihydrobenzoate SM255186_RS07415 acetyl-CoA C- SM255186_RS15905 synthase: enolpyruvyl-6-hydroxy- adenosyltranferase] adenosylcobalamin/ SM255186_RS03315 phosphorylase: SM255186_RS19225 pyruvate a,c-diamide adenosylcobinamide MepM: mepM muramoyl-L-alanyl-γ-D- (pentapeptide)peptidoglycan acyltransferase SM255186_RS03945 FadI: fadI synthase/ribosomal -CoA -CoA acetyl-CoA C- hydroxypyruvate sugar hydrolase/ helicase: protein] complex deaminase/5-amino-6-(5-phosphoribosylamino) sirohydrochlorin 2-dehydro- chitin degradation III (Serratia) SM255186_RS09530 acyltransferase: acyltransferase SM255186_RS01225 acyltransferase: cobA aminotransferase: 2,3-dihydro-2,3- 34 β adenosyltransferase: glycosyltransferase FadI: fadI nucleoside triphosphate 5'-nucleotidase 3- cyclohexene-1- alpha-ribazole Coα-[α-(benzimidazolyl) an epoxyqueuosine in tRNA 2-dehydro-3-deoxy- SM255186_RS21275 -D-ribofuranose 3-chlorobenzoate kinase/ bifunctional murein DD- plsY isoglutaminyl-L-lysyl- multifunctional acyl-CoA acetyl-CoA C- large subunit acyltransferase reductase B: ghrB plsY dnaB uracil reductase RibD: ribD SM255186_RS04685 glutamine- 3-deoxy-L- acyl-CoA peptidoglycan FadI: fadI aminoacyl-tRNA periplasmic precursor: carboxylate synthase: 7,8- phosphatase: ]-Coβ-adenosylcobamide gln dihydroxybenzoate degradation III cobO adenosylcobinamide- (glycyl) -D-alanyl-D-alanine FtsI: ftsI acetyl-CoA C- thioesterase I/protease acyltransferase pseudouridine FadI: fadI pyrophosphohydrolase: 3-(all-trans siroheme -tRNA phosphogluconate endopeptidase/murein 5 glycosyltransferase hydrolase: glyoxylate/ glycerol-3-phosphate replicative sirohydrochlorin 5-amino-6-(5-phospho- 4-phosphooxy- dehydrogenase: dhbA an α-limit dextrin rhamnonate chitin synthetase glycerol-3-phosphate acetyl-CoA C- SM255186_RS15005 SM255186_RS02585 SM255186_RS12175 dihydroneopterin -octaprenyl) superpathway of adenosylcobalamin salvage from cobinamide I synthase: cobA SM255186_RS03315 ligase: glnS aldolase: 2-keto-3-deoxy-L- (via gentisate) cob(I)yrinic acid phosphate LD-carboxypeptidase: peptidoglycan acyltransferase I/lysophospholipase L1: FadA: fadA synthase RluA: rluA acetyl-CoA C- hydroxypyruvate DNA a [cysteine desulfurase]- D-ribulose 5-phosphate D-ribitylamino)uracil cob(I)alamin- Coα-[α-(5- an L-glutaminyl- FdrA: afdrA 2-methyl 1-O-acyltransferase: FtsI: ftsI 3-[(3aS,4S,5R,7aS)- acyltransferase SM255186_RS09355 1-O-acyltransferase: sirohydrochlorin 2-succinyl-5- chorismate L-threonine a,c-diamide guanylyltransferase: glycosyltransferase FadA: fadA SM255186_RS02650 5-carboxy-2-methyl- IMP [+ 3 isozymes] bifunctional benzene-1,2-diol [corrinoid Gln [EntB aryl- SM255186_RS20030 4-alpha- rhamnonate aldolase: SM255186_RS11730 acetyl-CoA ribosomal large 3-oxo-2-(cis- acyltransferase Asn reductase A: SM255186_RS22055 helicase: S-sulfanyl-[disordered- 5-amino-6-(5- methoxybenzimidazolyl) [tRNA ] 2,3-dihydroxybenzoate 3-chlorobenzoate branched peptidoglycan peptidoglycan SM255186_RS220551-stearoyl- peptidoglycan mono-trans,octa- a peptidoglycan 5-hydroxy-7a-methyl- 3-oxopentanoyl-CoA FadA: fadA tRNA asn 1-palmitoyl- cobaltochelatase: enolpyruvoyl-6- siroheme 4-hydroxythreonine- Gln adenosyltransferase: SM255186_RS10630 AMP diphosphate FtsI: ftsI acetyl-CoA inosine dihydroneopterin bifunctional 3- adenosyltranferase] a tRNA carrier protein] 34 glucanotransferase: SM255186_RS12075 D-ribofuranose a purine adenosyl- palmitate subunit pseudouridine 2'-pentenyl)- (+)-7-FadA:epi fadA- SM255186_RS05625 dnaB form scaffold aminodeoxychorismate cob(II)inamide 3,4-dihydroxy- phospho-D- ]-Coβ-adenosylcobamide a queuosine in tRNA 2,3,4-saturated tetrapeptide, tetrapeptide, acyl-carrier protein sn-glycerol di-trans,octa-cisglycosyltransferase cis-decaprenyl dimer 1-oxo-octahydro-1H- acetyl-CoA acetyl-CoA sn-glycerol SM255186_RS10665 hydroxy-3-cyclohexene- aldolase/7,8- demethylubiquinone 3- 4-phosphate cob(I)yrinic acid enterobactin synthase D-glyceraldehyde a [cobalamin SM255186_RS10790 a holo-["base- ribonucleoside cobinamide a peptidoglycan synthase D: cyclopentane-1- jasmonoyl-CoA a single protein] complex 2-butanone- ribitylamino)uracil acyl carrier protein metabolism holo-ACP synthase: pyruvate SM255186_RS21280 β a [cyanocobalamin fatty acyl-CoA glycan chain 2 glycan chain 1 3-phosphate -undecaprenylFtsI: ftsI diphosphate (mycobacteria) indene-4-carboxyl-CoA hydroxypyruvate 3-phosphate cysteine desulfurase: 1-carboxylate synthase component 2: dehydrogenase 1: component D: ser [EntF L-seryl- 3-phosphate (S)-lactaldehyde [(1->4)- -N-acetyl-D- ribokinase: trafficking triphosphate off/His-on" 5'-diphosphate phosphate dimer (S. aureus) hexanoyl-CoA stranded DNA cobalt- dihydroneopterin O-methyltransferase/2- cob(I)yrinic acid a,c-diamide 4-phosphate a,c-diamide SM255186_RS13640 a debranched reductase CblC] SM255186_RS13825 2-succinyl-6-hydroxy- SM255186_RS21510 phosphatase SM255186_RS00465 D-glyceraldehyde SM255186_RS03000 carrier protein] glucosaminyl] -(1->4)-2- SM255186_RS19205 3-hydroxybenzoate diphosphate a pseudouridine 2605 sirohydrochlorin SM255186_RS08585 epimerase: octaprenyl-6-hydroxy adenosyltransferase: cobO synthase: ribB pyruvate adenosyltransferase: α-limit dextrin n protein CblD] B12-enzyme] aminodeoxychorismate YigB: yigB 3-phosphate a holo acyl- 4'-phosphopantetheinyl enterobactin synthase (acetylamino)-2-deoxy- ribokinase: in 23S rRNA cobalt-factor II C(20) cysteine 2, 4-cyclohexadiene-1- SM255186_RS16485 phenol methylase: cob(I)yrinic acid a,c-diamide 4-hydroxythreonine- cobO (2,3-dihydroxybenzoyl) chitin 3-hydroxybenzoate 1-deoxy-L-glycero- carrier protein transferase: component D: holo-ACP synthase: UDP-glucose D-glucono-1,5-lactone desulfurase carboxylate synthase: synthase component 1: SM255186_RS12005 adenosyltransferase: 4-phosphate 1-deoxy-D-xylulose-5- glu adenylate synthase: tRNA processing glycogen rbsK -methyltransferase: 6-(hydroxymethyl) ARP cob(I)yrinic acid SM255186_RS21005 SM255186_RS13640 4-epimerase: 6-monooxygenase: SM255186_RS12170 SM255186_RS09560 2-methoxy- tetrulose 4-phosphate phosphate synthase: SM255186_RS03060 SM255186_RS03000 phosphorylase: D-ribofuranose SM255186_RS10660 CsdA: csdA (1R,6R)-6-hydroxy-2- -7,8-dihydropterin SM255186_RS10790 dehydrogenase 2: a,c-diamide 13-DPG (S)-lactate SM255186_RS11525 undecaprenyl- an odd numbered a 3-methyl- sn-glycero-3- a long-linear an S-sulfanyl-[cysteine 6-(all-trans- an L-glutamyl- a holo-[EntF L- SM255186_RS03895 chitinase: 5-phosphate phosphoenol an [HPr]- sn-glycerol a (4Z)-hexadec- 9-carboxy-6-methyl-3,7- (S)-4- an L-cysteinyl- 3-oxopentanoyl- (R)-glycerate sn-glycerol D-mannitol acetyl-CoA 4-amino-4- SM255186_RS00855 SM255186_RS02185 adenosyltransferase: 4'-phosphopantetheinyl (2,3-dihydroxybenzoyl) a holo-[EntB aryl- (L-seryl)adenylate a polycistronic SM255186_RS21245 diphospho-N- straight chain branched 2,3,4- a myristoyl-[acp] a malonyl-[acp] phospho-N- α-D-glucan glycerophosphoglycerol adenosylcobinamide 3'-AMP cobalt-factor III desulfurase]-S- succinylcyclohexa-2,4- 2-amino-4-hydroxy-6- octaprenyl)phenol [corrinoid adenosyltranferase]-cob(II)inamide 6,7-dimethyl-8- [tRNA Glu ] α D-glucopyranose SM255186_RS00090 gentisate pyruvate L-histidine dioxononanoyl-CoA hydroxymandelate [tRNA Cys ] CoA 3-phosphate 1-phosphate deoxychorismate 3-amino-1- 1-deoxy-D- transferase: carrier protein] seryl-carrier protein] phosphoglycerate -D-glucopyranose maltodextrin [(1->4)-β-N-acetyl-D- 3-phosphate 4-enoyl-[acp] glycogen diene-1-carboxylate hydroxymethyldihydropteridine SM255186_RS10790 ACP glu adenylate tRNA precursor UDP-α-D-galactose acetylmuramoyl- UDP-N-acetyl- 2,3,4-saturated saturated fattylong-chain-fatty- acid phosphoenolpyruvate- glycerol-3- (arachidonoyl) glycerophosphodiester acetyl-CoA C- bifunctional mandelate racemase/ aminoacyl-tRNA acetyl-CoA C- glyoxylate/ glycerol-3- sugar/pyridoxal bifunctional 2',3'- acetyl-CoA sulfanyl-[disordered- 2-octaprenyl-6- ribityllumazine synthase: hydroxyacetone a tRNA 1-phosphate glucosaminyl] -(1->4) beta-ketoacyl- aminodeoxychorismate xylulose 5- adenosylcob(III) SM255186_RS21005 kinase: phosphorylase: n γ α long-chain-fatty- phosphorylase: acyltransferase adenosylcobinamide acyltransferase form scaffold o-succinylbenzoate diphosphokinase: phosphodiesterase: L-alanyl- -D- -D-glucosamine fatty acid acid--CoA ligase: -protein phosphate ACP synthase I: ethanolamineglycerophosphodiester phosphodiesterase: muconate lactonizing hydrolase: hydroxypyruvate phosphate phosphate cyclic-nucleotide 2'- carboxylase lyase: methoxyphenyl SM255186_RS02160 1-phosphate phosphate alamin-[corrinoid SM255186_RS15750 a chitodextrin -N-acetyl-2-deoxy- undecaprenyldiphospho- acid--CoA ligase: SM255186_RS21245 synthase: SM255186_RS00970 holo-ACP synthase: SM255186_RS02085 enterobactin synthase enterobactin synthase ribonuclease E: ribonuclease E: SM255186_RS21275 glutamyl-L-lysyl- SM255186_RS09530 phosphotransferase: acyltransferase: SM255186_RS12540 phosphodiesterase: SM255186_RS12035 FadI: fadI kinase/ enzyme family protein: SM255186_RS01225 FadA: fadA reductase A: acyltransferase: phosphatase phosphodiesterase/ carboxyl protein] complex SM255186_RS05980 hydroxylase: pyridoxine alpha-D-glucose 2-amino-D-gluconate SM255186_RS12160 (7,8-dihydropterin- adenosyltranferase] SM255186_RS13640 component D: component D: SM255186_RS05920 3-phospho- D-alanyl-D-alanine muramoylpentapeptide beta-N- SM255186_RS09530 SM255186_RS15315 SM255186_RS12035 maltodextrin acetyl-CoA C- adenosylcobinamide- SM255186_RS19485 acetyl-CoA C- SM255186_RS05625 YigL: yigL 3'-nucleotidase: transferase SM255186_RS15665 superpathway of thiamine diphosphate biosynthesis I pyridoxine 5'- SM255186_RS05920 phosphate-specific α glucokinase: ditrans,octacis- acyl-CoA plsY beta-ketoacyl- glycerophosphodiester aminoacyl-tRNA plsY 6-yl)methyl 6,7-dimethyl-8-(1-D-ribityl)lumazine pyridoxamine cob(I)yrinic acid SM255186_RS03000 SM255186_RS03000 D-glycerate -D- chitinase: acetylglucosaminyltransferase: acyl-CoA phosphorylase: phosphate SM255186_RS23715 subunit cobalt-precorrin-3 4-aminobenzoate 2-methoxy-6-all [corrinoid adenosyltranferase]-cob(I)inamide phosphoglucomutase: SM255186_RS12725 undecaprenyldiphospho- synthetase phosphoenolpyruvate- glycerol-3-phosphate ACP synthase II: glycerophosphodiester phosphodiesterase: acyltransferase mandelate racemase/ hydrolase: acyltransferase bifunctional glycerol-3-phosphate sugar phosphatase: 2-succinylbenzoate phosphate synthase: a,c-diamide glucopyranose SM255186_RS00090 murG guanylyltransferase: diphosphate trans-octaprenyl- pyridoxine kinase: ile a tRNA precursor a tRNA precursor with β synthetase -protein 1-O-acyltransferase: phosphodiesterase: SM255186_RS21275 SM255186_RS21150 FadA: fadA muconate lactonizing SM255186_RS09355 FadI: fadI glyoxylate/ 1-O-acyltransferase: SM255186_RS12305 alpha: accA a [cysteine riboflavin synthase: SM255186_RS13645 pyridoxine kinase: isoleucine--tRNA ligase: a 2,3-dihydroxybenzoyl- SM255186_RS03555 1-phosphate N-acetyl-(N-acetyl- -D- an odd numbered FdrA:a fdrA 3-methyl- SM255186_RS05975a (6Z)-3- α-D- 7-carboxy-4-methyl- 1,4-benzoquinol cob(I)yrinic acid a,c-diamide cys SM255186_RS12905 adenosyltransferase: an apo acyl- a seryl-[EntF L- with a 5' extension a 5' extension and UDP FdrA: fdrA phosphotransferase: ptsI SM255186_RS21150 a long-linear sn-glycerol SM255186_RS10630 enzyme family protein: hydroxypyruvate adenosine [+ 3 isozymes] o-succinylbenzoate- SM255186_RS12905 D-galactosamine and N-acetyl- glucosaminyl)muramoyl- SM255186_RS22055 acyl-carrier protein oxooctadec- glycerol acetyl-CoA a tRNA Cys cys propanoyl-CoA acetyl-CoA SM255186_RS22055 D-mannitol desulfurase]-(S- adenosyltransferase: cobO SM255186_RS08320 cobO carrier protein SM255186_RS00235 an L-isoleucyl- [EntB aryl- and a long 3' trailer a short 3' extension D-glucopyranose D-arabinose degradation I N,N'-diacetylchitobiose straight chain branched an [HPr protein]- 1-myristoyl- sn-glycerol glucopyranose α 3-phosphate 5-oxoheptanoyl-CoA adenosyl-cobinamide 1-oleoyl-sn -CoA ligase: seryl-carrier protein] γ diphosphate AMP diphosphate AMP π anandamide -D-glucan SM255186_RS11990 reductase B: ghrB malonyl-CoA sulfanyl) -[disordered- [tRNA Ile ] carrier protein] 2-phospho- 6-phosphate alpha-D-glucose D-galactosamine degradation L-alanyl- -D-glutamyl-L- 2,3,4-saturated 2,3,4-saturated N -phospho- pyruvate acyl-carrier protein sn-glycerol 6-enoyl-[acp] 3-phosphate 1-phosphate -glycerol 3- 2 cob(I)yrinic acid a,c-diamide cysteine desulfurase: ribonuclease D: ribonuclease P phosphate (R)-4- pyridoxine pyridoxamine cob(I)yrinic acid 10 Ile hydroxypyruvate form scaffold SM255186_RS12155 riboflavin N -formyl-tetrahydrofolate biosynthesis a tRNA ribonuclease PH: D-glycerate phosphate-specific L-rhamnose degradation I beta-hexosaminidase: N-acetyl-D- lysyl-D-alanyl-D-alanine fatty acyl CoA fatty acyl-CoA L-histidine 3-phosphate phosphate cobalt-precorrin-4 7,8- adenosyltransferase: SM255186_RS08585 5'-phosphate 5'-phosphate a,c-diamide SM255186_RS09525 protein component: D-arabinopyranose hydroxymandelate protein] complex 4-(2'-carboxyphenyl) 6-methoxy-3- enterobactin synthase ribonuclease D: SM255186_RS20200 phosphoglucomutase: SM255186_RS06035 galactosamine dihydropteroate SM255186_RS10790 bifunctional riboflavin cysteine adenosyltransferase: SM255186_RS19450 enolase: cobalt-precorrin-4 C(11) -4-oxobutyryl-CoA methyl-2-all- component D: SM255186_RS09525 L-fucose SM255186_RS03555 α kinase/FAD synthetase: desulfurase pyridoxal SM255186_RS10790 a tetrahydrofolate SM255186_RS14995 -L-rhamnopyranose 6-phosphateN-acetylglucosamine- -methyltransferase: bifunctional trans-octaprenyl- adenosylcobinamide pyridoxine/ pyridoxine/ lipoate biosynthesis SM255186_RS03000 a tRNA precursor with isomerase: fucI N-acetyl-D-glucosamine an E. coli a long-chain galactosyl-(1->3)-L-fucosyl- 3-(4- uridine 955/2504/ 2-methylacetoacetyl- 4-trans-3-oxo- uridine 2457 D-gluconate D-sorbitol 1,4-dihydroxy- SM255186_RS00230 CsdA: csdA chitin degradation II (Vibrio) L-rhamnose 6-phosphate 18-hydroxystearate a cis,cis-delta9,27- sn-glycerol a (3Z)-dec- glycerophosphoserine (S)-2- SM255186_RS10685 tetrahydrofolate 1,4-benzoquinol pyridoxamine 5'- pyridoxamine 5'- a short 3' extension phosphoenol osmoregulated an L-1- 2,3,4-saturated a malonyl-[acp] a palmitoyl-[acp] a malonyl-[acp] an oleoyl-[acp] a malonyl-[acp] glu (1->4)-O-acetyl-L-fucosyl- hydroxyphenyl) 2580 in 23S rRNA undecenoyl-CoA 6-phosphate 6-phosphate 3'-GMP a protein 2-naphthoyl- an [L-cysteine adenosylcobalamin and incorporation I leucine- mutarotase: rhaM deacetylase: C46:2-[acp] 3-phosphate 3-enoyl-[acp] aminobutanoate CoA in 23S rRNA a [cysteine desulfurase]- synthase/dihydrofolate 2-octaprenyl-3- bifunctional phosphate oxidase: phosphate oxidase: pyridoxine kinase: leu an N-(2,3- pyruvate D-ribulose periplasmic phosphatidylethanolamine long-chain-fatty- fatty acid beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- glycerophosphodiester (1->3)-β-D-glucopyranosyl- -3-oxo- bifunctional tRNA acetyl-CoA C- acetyl-CoA C- bifunctional tRNA 6-phosphogluconate sugar/pyridoxal bifunctional 2',3'- serine cobalt- CoA FMN desulfurase]-S- -tRNA a tRNA precursor β-L-rhamnopyranose SM255186_RS03480 long-chain-fatty- glycerol-3- glutamate-- [scaffold protein- synthase: methyl-6-methoxy- adenosylcobinamide SM255186_RS08200 SM255186_RS08200 SM255186_RS12905 dihydroxybenzoyl)- chitin D-glucopyranose D-galactosamine glucan (OPG) phosphoethanolamine acid--CoA ligase: phosphodiesterase: diphosphoundecaprenolcolanic acid propanoyl-CoA pseudouridine(32) acyltransferase acyltransferase pseudouridine(32) phosphate cyclic-nucleotide 2'- precorrin-5A synthase: sulfanyl-L-cysteine an octanoyl-[acp] with a 5' extension ribonuclease PH: ribonuclease D: pyruvate kinase I: acid--CoA ligase: ACP synthase I: phosphate ACP synthase II: ACP synthase II: cysteine ligase: acetyl-CoA C- phosphatase: endoprotease (2Fe-2S)] complex SM255186_RS12475 ligase: leuS an L-leucyl- seryl-[EntF L-seryl- L-fuculokinase: 6-phosphate 6-phosphate transferase: SM255186_RS09530 SM255186_RS21150 biosynthesis FadI: fadI FadI: fadI menB 1,4-benzoquinol kinase/adenosylcobinamide- bifunctional riboflavin cysteine desulfurase: methionine synthase: SM255186_RS08560 L-rhamnose isomerase: SM255186_RS09530 SM255186_RS12540 acyltransferase: SM255186_RS05975 SM255186_RS05975 SM255186_RS02995 acyltransferase synthase/ribosomal synthase/ribosomal SM255186_RS19405 phosphatase phosphodiesterase/ DegP: degP cobalt- a ThiS sulfur- [tRNA Leu ] SM255186_RS20200 SM255186_RS09525 chitinase: SM255186_RS15175 7,8-dihydrofolate hydroxylase: phosphate kinase/FAD synthetase: octanoyltransferase: carrier protein] SM255186_RS18860 SM255186_RS04200 acyl-CoA glycerophosphodiester acetyltransferase large subunit acetyl-CoA C- acetyl-CoA C- large subunit YigL: yigL 3'-nucleotidase: precorrin 5A carrier protein SM255186_RS08585 SM255186_RS21925 Leu pyruvate SM255186_RS00090 acyl-CoA beta-ketoacyl- plsY beta-ketoacyl- beta-ketoacyl- FadI: fadI fructose-1-phosphate/ serine 1,4-dihydroxy-2- PLP SM255186_RS03275 a tRNA enterobactin synthase glutamate- 2-O-acetyl-galactosyl-(1->3)-L-WcaB: wcaB (2E,6E)-farnesyl monoglutamate SM255186_RS03425 guanylyltransferase: SM255186_RS00230 a [lipoyl-carrier protein] kinase: pyk phosphoethanolamine synthetase ACP synthase II: ACP synthase I: ACP synthase I: phosphodiesterase: pseudouridine acyltransferase acyltransferase pseudouridine 6-phosphogluconate sugar phosphatase: SM255186_RS23715 endoprotease hydrolase: naphthoyl-CoA cysteine component D: D-ribulose 1-phosphate keto-L-rhamnulose an E. coli osmoregulated synthetase glycerol-3-phosphate -cysteine fucosyl-(1->4)-O-acetyl-L-fucosyl- acetyl-CoA C- a [co-chaperone]- diphosphate SM255186_RS10630 N 6 -octanoyl-L-lysine a chitodextrin D-tagatofuranose transferase CptA: cptA FdrA: fdrA SM255186_RS05975 SM255186_RS12540 SM255186_RS12540 SM255186_RS12035 synthase RluA: rluA FadA: fadA FadA: fadA synthase RluA: rluA phosphatase: SM255186_RS12305 DegQ: degQ cbiG 1,4-dihydroxy- 3-demethylubiquinol-8 FAD desulfurase SM255186_RS03000 pyruvate a 1,2-diacyl- periplasmic glucan with FdrA: fdrA a cis,cis- 1-O-acyltransferase: a (5Z)-3- an (11Z)-3- ligase: gshA (1->3)-β-D-glucopyranosyl- acyltransferase 2-trans- guanosine [scaffold protein- octaprenyl CsdA: csdA lipoprotein posttranslational modification 6-phosphate 18-hydroxystearoyl- a long-chain SM255186_RS22055 sn-glycerol γ-L-glutamyl-(S)- FadA: fadA [+ 2 isozymes] acetyl-CoA propanoyl-CoA acetyl-CoA [+ 2 isozymes] SM255186_RS14320 D-sorbitol cobalt- 2-naphthoyl- adenosyl-cobinamide phosphate lipoyl L-fuculose- sn-glycerol phosphotidylethanolamine AMP diphosphate acyl-carrier protein delta11,29-3- 1-palmitoyl- acyl-carrier protein oxododec- acyl-carrier protein oxo-icos-11- ser diphosphoundecaprenol 4-hydroxybenzoyl- a pseudouridine 955/ nonenoyl-CoA a pseudouridine 2457 a peptide (2Fe-2S)] complex a carboxy- a [ThiI sulfur- enterobactin Chemoautotrophic CoA AMP diphosphate 2,3,4-saturated 3-phosphate 2-aminobutanoate acetyl-CoA precorrin-5B CoA hydrolase: diphosphate synthase: synthase: lipA phosphate substituent oxo-C48:2-[acp] acyl-carrier protein sn-glycerol 5-enoyl-[acp] enoyl-[acp] CoA 2504/2580 in 23S rRNA in 23S rRNA D-gluconate a 7,8-dihydrofolate adenylated- carrier protein]- Energy Metabolism a [prolipoprotein]- fatty acyl CoA SM255186_RS08620 SM255186_RS16980 bifunctional molybdenum cofactor biosynthesis a [lipoyl-carrier val an uncharged tRNA aldolase: fucA 3-phosphate cobalt-precorrin- 5,6-dimethylbenzimidazole [ThiS sulfur- S-sulfanyl- D-glyceraldehyde valine--tRNA ligase: L-cysteine L-rhamnulofuranose all-trans-octaprenyl adenosylcobinamide tyr protein]-N 6 -[(R)- hydrogen oxidation a chitodextrin 5B (C(1))- 1,4-dihydroxy- carrier protein] L-cysteine 3-phosphate SM255186_RS24020 an L-valyl- D-tagatofuranose a [chaperone-ATP]- diphosphate polyisoprenoid biosynthesis (E. coli) ubiquinol-8 nicotinate-nucleotide-- dihydrolipoyl]-L-lysine I (aerobic) prolipoprotein rhamnulokinase: methyltransferase: 2-naphthoate kinase/adenosylcobinamide- Val 1,6-bisphosphate an inactive α ω lipid II (meso a 3-(all-trans 3-(all-trans N-acetyl-α- 1-palmitoyl- [co-chaperone]- dimethylbenzimidazole AIR 1-deoxy-D-xylulose-5- serine [tRNA ] diacylglyceryl DHAP glycolaldehyde (2E)- , -9Z- salicin 6- 3-(all-trans-heptaprenyl) 7,8- 3,22-dioxochol- SM255186_RS10700 phosphate 2-iminoacetate GTP Val SM255186_RS18855 a cis,cis-delta5,23- a (7Z)-hexadec- L(or D)-O- phosphate synthase: a tRNA tagatose-1,6- ribonucleoside a reduced hexadecenoate octadecenedioate a malonyl-[acp] DL-allothreonine a malonyl-[acp] diaminopimelate phosphate benzene-1,2-diol sn-glycerol 3-phosphate -polyprenyl) -decaprenyl) dihydroneopterin D-muramoyl- a malonyl-[acp] sn-glycerol 4-en-24-oyl-CoA a protein [scaffold protein- phosphoribosyltransferase: guanylyltransferase: synthase ATP hydroxymethyltransferase: H transferase: SAM C42:2-[acp] 7-enoyl-[acp] phosphoserine cobalt- 1,4-dihydroxy- a tetrahydrofolate IPP phosphomethylpyrimidine SM255186_RS02185 glycine cleavage 2 bisphosphate aldolase: triphosphate flavodoxin acyl-CoA acyl-CoA beta-ketoacyl- serine beta-ketoacyl- containing)peptidoglycan 6-phospho-beta- bifunctional 3- glycerol-3-phosphate benzene-1,2-diol benzene-1,2-diol bifunctional L-alanine(1-) beta-ketoacyl- phosphoserine 3-phosphate1-acyl-sn-glycerol- acetyl-CoA C- (2Fe-2S)] complex cobT ThiH: thiH cys SM255186_RS13530 Ni/Fe-hydrogenase, SM255186_RS15310 L-rhamnulose 1-phosphate bifunctional 3- bifunctional 3- N-acetylmuramoyl- HslU--HslV precorrin-6A 2-naphthoate SM255186_RS10630 synthase: a 7,8-dihydrofolate system proteina 5-methyltetrahydrofolate glucose and glucose-1-phosphate degradation SM255186_RS16730 reductase anaerobic synthetase synthetase ACP synthase II: glucosidase: demethylubiquinone 3- acyltransferase: plsY dihydroneopterin ACP synthase II: acyltransferase 1-deoxy-D- serine b-type cytochrome a [prolipoprotein]- beta-hexosaminidase: ACP synthase I: hydroxymethyltransferase: glycosyltransferase demethylubiquinone 3- demethylubiquinone 3- L-alanine phosphatase: 3-phosphate peptidase cobalt-precorrin- polyprenyltransferase: tetrapyrrole biosynthesis SM255186_RS18285 a thiocarboxy- molybdopterin- H: gcvH ribonucleoside- FdrA: fdrA FdrA: fdrA SM255186_RS08830 O-methyltransferase/2- aldolase/7,8- FadI: fadI isopentenyl- α-ribazole 5'-phosphate xylulose 5- 2-iminoacetate cysteine desulfurase: S-1,2-diacyl-sn- SM255186_RS06035 D-glyceraldehyde SM255186_RS12540 SM255186_RS13530 SM255186_RS05975 FtsI: ftsI glycerol-3-phosphate O-methyltransferase/2- O-methyltransferase/2- amidase SM255186_RS05975 SM255186_RS24585 acyltransferase: ATPase SM255186_RS18635 adenosylcobinamide-GDP [ThiS-Protein] synthase hydroxymethyltransferase: subunit: cybH N,N'- N,N',N''- glycolate α-D- DHAP triphosphate reductase 6A reductase: I (from glutamate) diphosphate phosphate (8S)-3',8-cyclo-7,8- glyceryl-L-cysteine 3-phosphate long-chain-fatty- long-chain-fatty- beta-ketoacyl- serine beta-ketoacyl- peptidoglycan 6-phospho-beta- octaprenyl-6-hydroxy 1-O-acyltransferase: octaprenyl-6-hydroxy octaprenyl-6-hydroxy dihydroneopterin AmiB: amiB beta-ketoacyl- phosphoserine 1-palmitoyl-2-SM255186_RS16320 acetyl-CoA C- subunit: HMP-P adenylyltransferase SM255186_RS08585 SM255186_RS18560 ala Ni/Fe-hydrogenase diacetylchitobiose triacetylchitotriose glucopyranose activating protein: SM255186_RS10670 Delta-isomerase: dihydroguanosine Metabolic Regulator Biosynthesis acid--CoA ligase: acid--CoA ligase: hydroxymethyltransferase: glucosidase: phenol methylase: SM255186_RS22055 phenol methylase: phenol methylase: epimerase: acyltransferase hslU a [chaperone- MoeB: moeB cysteine alanine--tRNA ligase: (S)-lactaldehyde DHAP 1-phosphate SM255186_RS23880an active ACP synthase II: ACP synthase I: glycosyltransferase [+ 3 isozymes] ACP synthase I: phosphatase palmitoleoyl- an [2Fe-2S] SM255186_RS15560 adenosylcobinamide- thiazole synthase: 5'-triphosphate b-type cytochrome lipoprotein beta-hexosaminidase: fucose degradation SM255186_RS09530 SM255186_RS09530 SM255186_RS15630 SM255186_RS12005 1-(18-hydroxyoleoyl)- SM255186_RS16485 N-acetyl-D- FadA: fadA cobalt- ADP]-[disordered- demethylmenaquinol-8 glu thiamine salvage II bifunctional a carboxy- desulfurase thymidylate synthase: SM255186_RS14345 an L-alanyl- a flavodoxin ribonucleoside SM255186_RS05975a cis,cis- SM255186_RS18560 SM255186_RS12540a (9Z)-3-oxo- lipid II (meso di-trans,octa-cisFtsI: ftsI a 2-methoxy-SM255186_RS12005 6-(all-trans- SM255186_RS12005 ala a 3- SM255186_RS12540 SerB: serB sn-glycerol a peptide cluster protein GDP ribazoletransferase: SM255186_RS18305 subunit: signal peptidase: SM255186_RS06035 met 5'-deoxyadenosine ω-carboxy- β-D-glucose 2-methoxy-6-(all-trans sn-glycrol 3-phosphate 7,8- muramate 3-oxo-4-pregnene- precorrin-6B form scaffold hydroxymethylpyrimidine adenylated CsdA: csdA cyclic pyranopterin SM255186_RS15305 [tRNA Ala ] ppGpp biosynthesis semiquinone triphosphate (2E)- gly acetaldehyde diaminopimelate -undecaprenyl salicyl alcohol 6-(all-trans- decaprenyl)-2- oxodocosanoyl- serine 3-phosphate DMAPP SM255186_RS10625 mannosylglycerate SM255186_RS09380 N-acetyl-D- glucose-1-phosphatase: AMP diphosphate AMP diphosphate (9Z)-octadec- acyl-carrier protein delta7,25-3- acyl-carrier protein octadec-9- 6-phosphate -heptaprenyl)phenol dihydromonapterin 20-carboxyl-CoA cobalt-precorrin- protein] complex 4-amino-2-methyl-5- kinase/ [small subunit of an [L-cysteine monophosphate a tRNA Ala SM255186_RS00240 β-L-fucopyranose reductase polyprenyl)phenol methoxy-phenol 2-[(2R,5Z)- A(H2) glucosamine trehalose degradation II (cytosolic) alpha-D-glucose SM255186_RS18975 L-arabinose degradation I hexadecenoyl-CoA 9-enoyl-CoA oxo-C44:2-[acp] enoyl-[acp] containing) diphosphate [acp] an L-glutamyl- pyrimidinemethanol phosphomethylpyrimidine molybdopterin desulfurase]-S- synthase: biosynthesis I L-fucose mutarotase: 6B (C(15))- (2E,6E)-farnesyl 2-carboxy-4- pppGpp an (S-diacyl-sn- phosphate-specific [+ 3 isozymes] methyltransferase [tRNA Glu ] bifunctional kinase: thiD synthase] sulfanyl-L-cysteine SM255186_RS04030 GDP-α-D- a lipoprotein SM255186_RS15180 diphosphate synthase: adenosylcobalamin 5'-phosphate methylthiazol-5(2H guanosine-5'- glyceryl)-L-cysteinyl- α,α-trehalose phosphoglucomutase: L-arabinopyranose (decarboxylating): hydroxymethylpyrimidine mannose signal peptide α-L-fucopyranose an [Fe-S cluster NAD de novo biosynthesis glutamyl-tRNA SM255186_RS02190 )-ylidene]ethyl cyclic pyranopterin triphosphate,3'-diphosphate [apolipoprotein] SM255186_RS03555 glucokinase: D-glucopyranose L-arabinose isomerase: (15Z)- arbutin-6- methyl β-D-glucoside 6-cis, 3-oxo- β-L-galactose an organic a 1-acyl-sn an L-1- SM255186_RS10690 kinase/ HMP-PP GTP diphosphokinase: 16-hydroxypalmitate a glutaryl-[acp] a cis,cis-delta7,25- a (7Z)-hexacos- an N-modified an unsulfurated [DNA] biosynthesis I (from aspartate) reductase: adenosylcobalamin/alpha- phosphate monophosphate a (6S)-5- asparagine-- guanosine-3',5'- pyrophosphatase: apolipoprotein N- tetracosenoate a malonyl-[acp] a malonyl-[acp] a peptidyl-[tRNA] a charged tRNA a malonyl-[acp] phosphate cys sn-glycerol 3-phosphate 6-phosphate tridecenoyl-CoA 1-phosphate hydroperoxide thr -glycerol 3- a protein phosphatidyl- geranyl asn 2-O-(α-D- chitobiose degradation alpha,alpha- L-fucose SM255186_RS12725 SM255186_RS00535 methyl ester C44:2-[acp] 7-enoyl-[acp] aminoacyl-[tRNA] [sulfur carrier] chaperone]-ATP SM255186_RS09325 ribazole phosphatase: phosphomethylpyrimidine synthase SM255186_RS15060 bis(diphosphate) SM255186_RS17845 acyltransferase: long-chain-fatty- acyl-CoA 6-phospho-beta- glycerol-3-phosphate 6-phospho-beta- acetyl-CoA C- thiol peroxidase: DNA polymerase phosphate sn-glycerol cobalt-precorrin-7 diphosphate bifunctional formyltetrahydrofolate tRNA ligase: trehalase TreF: treF isomerase: fucI L-ribulose beta-ketoacyl- beta-ketoacyl- bifunctional glycosyl beta-ketoacyl- aminoacyl-tRNA cysteine sugar/pyridoxal serine/threonine 1-acyl-sn-glycerol- D-alanyl-D-alanine- lipid SM255186_RS03315 kinase: thiD thiamine phosphate a thiocarboxylated MoaC: moaC mannosyl)- acid--CoA ligase: synthetase glucosidase: glucosidase: acyltransferase SM255186_RS06745 III subunit epsilon: asp (S)-4-amino-5- methylenetetrahydrofolate 5-formyltetrahydrofolate SM255186_RS04800 an L-asparaginyl- 3'-diphosphatase: SM255186_RS03400 N,N'-diacetylchitobiose D-glucopyranose ACP synthase I: ACP synthase I: transferase/ ACP synthase I: hydrolase: desulfurase acyltransferase: plsY phosphate dehydratase: 3-phosphate carboxypeptidase/ kinase (2E,6E)-farnesyl synthase: [small subunit of cyclic 3-phospho- an N-acyl-(S-diacyl- SM255186_RS09530 FdrA: fdrA SM255186_RS08830 SM255186_RS08830 FadI: fadI SM255186_RS01355 cobalt-precorrin-7 (C(5) oxopentanoate dehydrogenase/ cyclo-ligase: [tRNA Asn ] SM255186_RS20160 a peptide 6'-phosphate L-fuculose 6-phosphate D-glucono- SM255186_RS12540 SM255186_RS12540 transpeptidase: SM255186_RS12540 SM255186_RS01225 CsdA: csdA glycerol-3-phosphate phosphatase thioredoxin-dependent SM255186_RS16680 acyltransferase: endopeptidase YegS: L-aspartate oxidase: diphosphate synthase: adenosylcobalamin HMP-P molybdopterin pyranopterin D-glycerate sn-glyceryl)-L- chitin disaccharide α-D-glucopyranose β-D-glucopyranose ribulokinase: araB )-methyltransferase: SM255186_RS22130 methenyltetrahydrofolate tRNA Asn acyl-CoA synthetase long-chain-fatty- 6-phospho-beta- 1-O-acyltransferase: 6-phospho-beta- acetyl-CoA C- YigL: yigL thiol peroxidase: DNA polymerase SM255186_RS16320 AmpH: ampH yegS SM255186_RS13710 glutamate-1- SM255186_RS02190 5-(2-hydroxyethyl) phosphopantothenate biosynthesis I synthase] phosphate SM255186_RS15690 mannosyl-3- deacetylase: L-fuculokinase: 1,5-lactone beta-ketoacyl- beta-ketoacyl- SM255186_RS01005 beta-ketoacyl- aminoacyl-tRNA cysteine desulfurase: threonine a 1-acyl-2- 1-(3-sn- SM255186_RS10695 thiamine phosphate cyclohydrolase FolD: folD cysteinyl-[lipoprotein] FdrA: fdrA acid--CoA ligase: glucosidase: SM255186_RS22055 glucosidase: acyltransferase SM255186_RS13195 V subunit UmuD: citrate lyase activation 2-iminosuccinate semialdehyde bifunctional -4-methylthiazole a 5,10- a 5,10- phosphoglycerate SM255186_RS08825 SM255186_RS15175 SMP-30/ L-ribulose 5-phosphate ACP synthase II: ACP synthase II: transpeptidase: ACP synthase II: hydrolase: SM255186_RS08585 sugar phosphatase: ammonia-lyase, palmitoyl-sn [+ 2 isozymes] phosphatidyl) (2E,6E)-farnesyl GTP ppGpp N-monoacetylchitobiose SM255186_RS09530 1-arachidinoyl-sn- SM255186_RS10440 2,1-aminomutase: hydroxymethylpyrimidine synthase: 3-methyl-2- molybdopterin synthase methylenetetrahydrofolate methenyltetrahydrofolate SM255186_RS05975 SM255186_RS05975 SM255186_RS01680 SM255186_RS05975 SM255186_RS09355 SM255186_RS15630 a sulfurated SM255186_RS15630 FadA: fadA SM255186_RS12305 an alcohol -glycerol 3- -sn-glycerol cobalt-precorrin-8 diphosphate hydroxyethylthiazole phosphatase- gluconolactonase/ diphosphate 16-hydroxypalmitoyl-CoA a cis,cis- a (9Z)-3- β-D-glucose ala β-D-glucose 4-cis- biosynthetic: ilvA a peptide quinolinate kinase/ SM255186_RS18290 oxobutanoate 6'-phosphate D-mannose degradation L-ribulose-5-phosphate AMP a 3-oxopimeloyl- an uncharged a peptidyl- an N-modified an uncharged [sulfur carrier] glycerol 3-phosphate acetyl-CoA a nucleoside 5'- SM255186_RS01030 kinase: catalytic subunit: bifunctional related protein: L-fuculose 1-phosphate LRE family protein: (15Z)- acyl-carrier protein acyl-carrier protein delta9,27-3- acyl-carrier protein oxooctacos- hydroquinone MeOH undecenoyl-CoA L-galactopyranose 2-oxobutanoate phosphate 3-phosphate 3'-dephospho-CoA synthase: phosphomethylpyrimidine 6-phospho-beta- AMP diphosphate [acp] methyl ester tRNA aminoacyl-[tRNA] amino acid tRNA 6-phosphate 6-phosphate monophosphate superpathway of heme b biosynthesis SM255186_RS11380 3-methyl-2-oxobutanoate SM255186_RS04050 methylenetetrahydrofolate aspartate- SM255186_RS10370 5-oxo-L-proline metabolism D-glucopyranose SM255186_RS13850 4-epimerase: araD tetracosenoyl-CoA oxo-C46:2-[acp] 9-enoyl-[acp] nadA 5-aminolevulinate octaprenyl adeninyl adenosylcobamide 2-methyladeninyl L-fuculose- D-mannopyranose triphosphoribosyl- from uroporphyrinogen-III kinase: thiD thiamine hydroxymethyltransferase: dehydrogenase/ -tRNA 2-O-(α-D- glucosidase: [+ 2 isozymes] diphosphate synthase: 4-methyl-5-(2- biosynthesis from adenosylcobamide biosynthesis asp GTP diphosphokinase: phosphate 6-phosphate dephospho- phosphate panB methenyltetrahydrofolate ligase: guanosine-3',5'- mannosyl)- a [protein] with a [protein] with SM255186_RS08830 glucokinase: mannose-6- D-gluconate quinolinate porphobilinogen di-trans,octa-cis SM255186_RS16980 HMP-PP phosphooxyethyl) adenosylcobinamide-GDP molybdopterin from adenosylcobinamide-GDP 5-methoxy-6-methylbenzimidazolyl SM255186_RS15060 aldolase: fucA D-xylulose 5-phosphate cobyrinate CoA synthase: uroporphyrinogen-III thiamine- aspS an L-aspartyl- D-glycerate an N-terminal an N-terminal 6-phospho-beta- SM255186_RS12725 phosphate isomerase: an [amino group carrier synthase: -undecaprenyl thiazole adenosylcobamide biosynthesis cyclohydrolase FolD: folD nucleoside- bis(diphosphate) a UDP-sugar 3-oxo-(9Z)- 6-trans-3-oxo- a [protein]-L- 3-oxopalmitoyl- 2-dehydropantoate 2-methyladenine asp L-glutamate glucosidase: 18-hydroxyoleate pentadecanoate a malonyl-[acp] a cis,cis-delta3,21- a maltodextrin a (5Z)-tetracos- a peptidoglycan a lipid II a [protein] (L-serine/L- a ribonucleoside an ADP-sugar SM255186_RS00320 SM255186_RS01915 all-trans- phosphate kinase: molybdopterin [tRNA ] diphosphate kinase: 3'-diphosphatase: L-glutamine (S)-lactaldehyde DHAP SM255186_RS08100 a malonyl-[acp] a malonyl-[acp] a malonyl-[acp] sn-glycerol 3-phosphate ω protein]-C-terminal-γ- diphosphate uroporphyrinogen adenine from adenosylcobinamide-GDP asp hexadecenoyl-CoA tridecenoyl-CoA proline ( = 180) CoA IMP cobyrinate a,c- thiamine phosphate nicotinate-nucleotide-- a 10-formyltetrahydrofolate tRNA SM255186_RS15630 D-glucopyranose 6-phosphate long-chain-fatty- methyl ester C40:2-[acp] glycogen 5-enoyl-[acp] bifunctional UDP- threonine) phosphate 5'-monophosphate dITP ADP 2-(5''-triphosphoribosyl)- octaprenyl decarboxylase: SM255186_RS02170 2-dehydropantoate nicotinate-nucleotide-- adenylyltransferase: 5-methoxy-6- SM255186_RS13380 SM255186_RS20160 mannose-1-phosphate long-chain-fatty- beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- peptidoglycan glycerol-3-phosphate acetyl-CoA C- acetyl-CoA C- bifunctional FKBP-type acetyl-CoA C- (L-glutamyl)-L-glutamate diamide synthase: undecaprenyl- dimethylbenzimidazole sugar hydrolase/ protein phosphatase XTP/dITP diphosphatase: porphobilinogen synthase: 2-reductase: SM255186_RS00040 GDP Respiration N-acetyl-D-glucosamine guanylyltransferase/ trehalose degradation I (low osmolarity) acid--CoA ligase: acid--CoA ligase: phosphorylase: glycosyltransferase acyltransferase acyltransferase peptidyl-prolyl cis- acyltransferase guanosine compounds SM255186_RS10715 3'-dephosphocoenzyme- diphosphate diphosphate SM255186_RS18270 thiamine dimethylbenzimidazole phosphoribosyltransferase: methylbenzimidazole ACP synthase I: ACP synthase I: ACP synthase I: 5'-nucleotidase CheZ: cheZ acyltransferase: plsY metallophosphatase/ acetylglutamate NaMN glutathione-peroxide SM255186_RS22130 molybdopterin nicotinate-nucleotide-- NAD salvage pathway I (PNC VI cycle) 6-phosphate D-xylose degradation I SM255186_RS09530 SM255186_RS09530 SM255186_RS21245 FtsI: ftsI FadA: fadA FadI: fadI trans isomerase: FadA: fadA SM255186_RS15905 monophosphate hydrolase A synthase: hydroxymethylbilane phosphatase: diphosphate SM255186_RS02245 phosphoribosyltransferase: mannose-6- SM255186_RS12540 SM255186_RS12540 SM255186_RS12540 periplasmic precursor: protein-serine/ glycerol-3-phosphate 5'-nucleotidase: kinase: argB cob(II)yrinate coproporphyrinogen III redox reactions adenine cobT dimethylbenzimidazole 2-oxoglutarate decarboxylation to succinyl-CoA a [protein] with α,α-trehalose maltodextrin nucleoside triphosphate reductase: NudE: nudE SM255186_RS03190 SM255186_RS04315 thiamine phosphate β cobT γ-L-glutamyl phosphate isomerase: acyl-CoA synthetase acyl-CoA synthetase peptidoglycan 1-O-acyltransferase: acetyl-CoA C- acetyl-CoA C- SM255186_RS00170 SM255186_RS00245 acetyl-CoA C- an [amino group carrier a,c-diamide nicotinate-nucleotide synthase: -alanine (R)-pantoate dinucleotide phosphoribosyltransferase: an N-terminal 5- trehalose degradation beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- SM255186_RS02585 threonine phosphatase: SM255186_RS00745 synthase: adenine ribotide 2-methyladenine + glutathione 6-phosphate phosphorylase: [+ 7 isozymes] pyrophosphohydrolase: 2'-(5''-triphospho-α-D- adenylyltransferase: SM255186_RS17720 NAD tyr 5-phosphate fructose degradation melibiose degradation SM255186_RS10985 D-xylose FdrA: fdrA FdrA: fdrA ACP synthase II: ACP synthase II: ACP synthase II: glycosyltransferase SM255186_RS14750 SM255186_RS22055 acyltransferase acyltransferase [+ 3 isozymes] acyltransferase protein]-C-terminal- an α-D-aldose undecaprenyl- GSSG molybdopterin ribotide phosphate 5-methoxy-6- cobT a [2-oxoglutarate oxo-L-proline VI (periplasmic) SM255186_RS21275 an α-D-aldose a [protein]-L- SM255186_RS15005 AMP ribosyl)-3'-dephospho-CoA SM255186_RS18290 phosphate tyrosine--tRNA ligase: F6P xylose FtsI: ftsI UMP 1-C16:0-α,ω-dicarboxyl- FadI: fadI FadA: fadA FadI: fadI γ-(5-phospho-L- GMP 1-phosphate SM255186_RS03325 diphosphatase: molybdotransferase: methylbenzimidazole dehydrogenase SM255186_RS05975 SM255186_RS05975a cis,cis- α SM255186_RS05975a (7Z)-3- di-trans,octa-cis 1-phosphate a [protein] Ser/Thr a ribonucleoside proline (ω = 0) preuroporphyrinogen pantoate--beta- SM255186_RS08195 α α β alpha,alpha- isomerase: AMP diphosphate 18-hydroxyoleoyl-CoA AMP diphosphate pentadecanoyl-CoA a 3-oxoglutaryl- -D-glucopyranose 2-lysophosphatidate (7Z)- 4-trans- dIMP citrate lyase holo- SM255186_RS16480 an L-tyrosyl- 6 , -trehalose -D-fructofuranose melibiose a maltodextrin acetyl-CoA acetyl-CoA myristoyl-CoA acetyl-CoA glutamyl)-L-glutamate nicotinate adenine NAD salvage pathway II (PNC IV cycle) adenosylcobinamide- SM255186_RS04255 adenosylcobinamide- ribotide phosphate NADH E2 protein] N phosphotrehalase: acyl-carrier protein acyl-carrier protein delta5,23-3- 1-phosphate acyl-carrier protein oxohexacos- -undecaprenyl a peptidoglycan tetradecenoyl-CoA undecenoyl-CoA di-trans,octa-cis thiamine alanine ligase: [tRNA Tyr ] 1-phosphate xylA [acp] methyl ester [acyl-carrier protein] dinucleotide uroporphyrinogen- GDP MoO - GDP adenosylcobinamide- -lipoyl-L-lysine 1-phosphofructokinase: alpha-glucosidase/ oxo-C42:2-[acp] 7-enoyl-[acp] diphosphate -undecaprenyl protoporphyrinogen IX protoporphyrinogen IX glutathione- phosphate SM255186_RS00925 2 pyrophosphatase: a tRNA Tyr treC D-xylulose synthase: citX III synthase: ribazoletransferase: molybdopterin ribazoletransferase: GDP 2-oxoglutarate alpha,alpha- SM255186_RS11680 alpha-galactosidase: NAD(+) synthetase: disulfide reductase: + SM255186_RS18275 phosphate thiamine- NAD cofactor dehydrogenase 2-oxoglutarate 5-oxo-L-proline SM255186_RS22395 citrate lyase holo- SM255186_RS08865 SM255186_RS17725 SM255186_RS10625 α α SM255186_RS10625 ribazoletransferase: trehalase TreF: treF 1-phosphofructokinase: xylulokinase: SM255186_RS20905 Coα-[α-(adenin- Co -[ -(2- glucokinase: a cis,cis- a peptidoglycan 3-oxo-(11Z)- sn-glycerol [acyl-carrier protein] NAD salvage protoporphyrinogen phosphate kinase: (R)-pantothenate SM255186_RS10625 nicotinate adenine E1 component: dehydrogenase D-galactopyranose D-glucopyranose SM255186_RS20590 7-hydroxylaurate α-linolenate an acyl-[acyl- maltoheptaose a (3Z)-docos- maltotetraose a supercoiled duplex DNA maltose a 3-oxoacyl-CoA 3',5'-ADP 9-yl)]-Coβ- methyladenin-9-yl)]-Co NMN Secondary Metabolite Biosynthesis 5-oxoprolinase β-D-fructose 1,6-pfkB a malonyl-[acp] delta17,29- a malonyl-[acp] a malonyl-[acp] dimer (S. aureus) a type IV prepilin glu ala octadecenoyl-CoA an arachidoyl-[acp] + uroporphyrinogen-III pathway IV (from SM255186_RS02170 Coα-[α-(5-methoxy-6- dinucleotide sucA E1 component: D-glucopyranose SM255186_RS12725 carrier protein] 3-enoyl-[acp] XTP 3-phosphate dIDP synthase: citX NAD oxidase: β subunit galactose-1-epimerase: galM D-glucopyranose D-xylulose long-chain-fatty- acyl-CoA synthetase C48:2-[acp] maltodextrin maltodextrin serine-type D-Ala-D- ATP-dependent DNA acetyl-CoA C- alpha-glucosidase: acetyl-CoA C- adenosylcobamide -adenosylcobamide methylbenzimidazolyl)]- tryptophan- α β bisphosphate beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- prepilin peptidase: glutamate-- anaerobic glycerol- 3'(2'),5'- nicotinamide riboside) SM255186_RS17465 thiamine dihydrolipoyl sucA PxpB: pxpB -D-glucopyranose -D-glucopyranose 6-phosphate 5-phosphate FdrA: fdrA phosphorylase: phosphorylase: Ala carboxypeptidase: helicase RecQ: recQ acyltransferase beta-ketoacyl- SM255186_RS19010 acyltransferase XTP/dITP diphosphatase: a holo [citrate lyase 1-(β-D 5'-phosphate 5'-phosphate β nicotinate-nucleotide -tRNA autoinducer AI-2 biosynthesis I acid--CoA ligase: ACP synthase II: ACP synthase I: ACP synthase I: SM255186_RS21650 3-phosphate nucleoside- bisphosphate glutathione diphosphate Co -adenosylcobamide preQ biosynthesis myo-inositol biosynthesis dehydrogenase: SM255186_RS21275 SM255186_RS21275 SM255186_RS03285 cysteine ligase: ACP synthase I: SM255186_RS15905 adenosylcobalamin/ 0 SM255186_RS09530 long-chain-fatty- ATP-dependent FadA: fadA alpha-glucosidase/ FadA: fadA acyl-carrier protein] ribofuranosyl) NADH adenosylcobalamin/ 5'-phosphate adenylyltransferase: ligase: trpS a [2-oxoglutarate a [2-oxoglutarate SM255186_RS05975 SM255186_RS12540 SM255186_RS12540 prepilin peptidase: SM255186_RS02995 dehydrogenase: diphosphate kinase: nucleotidase lpdA glu glycogen [+ 2 isozymes] SM255186_RS12540 alpha-galactosidase: nucleoside triphosphate nicotinamide protoporphyrin IX pyrophosphatase: (R)-4'- alpha-ribazole alpha-ribazole adenosylcobalamin/ SM255186_RS03325 dehydrogenase dehydrogenase acyl-CoA synthetase acid--CoA ligase: glycogen SM255186_RS22640 DNA helicase Rep: acetyl-CoA C- acetyl-CoA C- SM255186_RS12045 SM255186_RS13380 CysQ: cysQ [citrate (pro-3S)- trifunctional Trp tryptophan- D-glucopyranose beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- a peptidoglycan glutamate--cysteine a 3- 5-hydroxybenzimidazolyl phosphopantothenate phosphatase: a tRNA SAM 6 6 SM255186_RS09530 phosphorylase: phosphorylase: a cleaved type SM255186_RS17850 SM255186_RS22395 pyrophosphohydrolase: nicotinamide-nucleotide SM255186_RS18275 phosphatase: alpha-ribazole -tRNA E2 protein] N E2 protein] N -S- FdrA: fdrA ACP synthase I: ACP synthase II: ACP synthase II: D-ala with D,D cross- a peptide acyltransferase oxodocosanoyl- acyltransferase glpB glpC lyase] ligase: citC NAD salvage GTP 6-phosphate SM255186_RS21245 SM255186_RS21245 ligase: gshA SM255186_RS15005 AMP adenosylcobamide biosynthesis ferrochelatase: SM255186_RS03315 SM255186_RS03315 phosphatase: -dihydrolipoyl- succinyldihydrolipoyl- SM255186_RS05975 IV prepilin a single stranded DNA FadI: fadI D-glucopyranose FadI: fadI DHAP dITP pathway III (to adenylyltransferase/ α α Coα-[α-(2- NaMN nicotinamide ligase: trpS an L-tryptophanyl- GTP α SM255186_RS12540 SM255186_RS05975a cis,cis- α-D-glucopyranose a (5Z)-3- α-D-glucopyranose link (S. aureus) γ-L-glutamyl-D-alanine [acp] [citrate (pro-3S)- from adenosylcobinamide-GDP SM255186_RS02560 Co -[ -(adenin- folate polyglutamylation bifunctional L-lysine L-lysine AMP diphosphate 7-hydroxylauroyl-CoA AMP diphosphate -linolenoyl-CoA XMP nicotinamide riboside) ribosylnicotinamide SM255186_RS03315 [tRNA Trp ] acyl-carrier protein a 3-oxoacyl-[acp] acyl-carrier protein delta19,31-3- maltohexaose acyl-carrier protein oxotetracos- maltotriose palmitoleoyl-CoA acetyl-CoA acetyl-CoA an acyl-CoA lyase] ligase: citC nicotinate adenine dinucleotide NMN 7-yl)]-Coβ- methyladenin-7-yl)]-Co Coα-[α-(5-methoxy-6- nicotinamidase/ cyclohydrolase Fatty Acid and Lipid Degradation 1-phosphate 1-phosphate 5-hydroxybenzimidazole NaMN kinase/transcriptional nicotinamide trp SAH 7,8- Ins(3)P oxo-C50:2-[acp] 5-enoyl-[acp] NADP + protoheme adenosylcobamide β-adenosylcobamide methyl-benzimidazolyl)]- pyrazinamidase: I FolE: folE 5-(methoxycarbonylmethoxy) an acetyl-holo [citrate nicotinate-nucleotide-- regulator NadR: 5-methylbenzimidazolyl dihydroneopterin mononucleotide a tetrahydrofolate Coβ-adenosylcobamide SM255186_RS08950 uridine biosynthesis oleate β-oxidation lyase acyl-carrier protein] dimethylbenzimidazole SM255186_RS24595 adenosylcobamide biosynthesis nicotinate 5'-methylthioadenosine/ 3'-triphosphate bifunctional glucose- deamidase-related fatty acid β-oxidation I 6 γ from adenosylcobinamide-GDP phosphoribosyltransferase: S-adenosylhomocysteine 2-oxoglutarate Aromatic Compound Degradation core an O - a cis,cis- (6Z,9Z,12Z,15Z,18Z)-3- L-alanyl- -D- cis-vaccenyl 3-oxo-(7Z)- a guanine 1835 cytidine 2',3'-cyclic 3-oxomyristoyl- (5E)-3-oxo- (1S,2R)-1- a protein-L- phosphoribosyltransferase: NMN protein YfaY: cinA 6-carboxytetrahydropterin 1-phosphatase/ a [protein]- maltopentaose a (5Z)-tetradec- an acetyl ester NAD + folate transformations I bifunctional serine pncB nucleosidase: mtnN dehydrogenase prephenate SAM an L-1- oligosaccharide- methylguanine a palmitoleoyl-[acp] a malonyl-[acp] delta15,27- a malonyl-[acp] a malonyl-[acp] oxotetracosapentaenoyl-CoA glutamyl-L-lysyl- acetate tetradecenoyl-CoA in 23S rRNA monophosphate CoA dodec-5- C-(indol-3- methionine- cobT 5-methylbenzimidazole NaMN inositol phosphatase: oleate a (3Z)-alk-3- L-cysteine maltodextrin 5-enoyl-[acp] ATP a ribonucleic acid ser IDP 5-hydroxybenzimidazole nicotinamide- tetrahydrofolate hydroxymethyltransferase: threonine- synthase QueD: queD E1 component: carboxy-S- lipid A (E. coli in DNA beta-ketoacyl- C46:2-[acp] beta-ketoacyl- acetyl-CoA C- D-alanyl-D-alanine acetylesterase: acetylesterase: acetyl-CoA C- ribosomal RNA bifunctional 2',3'- acetyl-CoA C- enoyl-CoA yl)glycerol (R)-S-oxide trifunctional nicotinate thr SM255186_RS05525 enoyl-CoA parathion degradation phosphatidylethanolamine bifunctional DNA- beta-ketoacyl- serine-type D-Ala-D- acetyl-CoA C- peptide- ribotide phosphate NADH nucleotide amidase: nicotinate-nucleotide-- SM255186_RS13530 -tRNA S-ribosyl-L-homocysteine sucA adenosyl-L- long-chain-fatty- chlorpyrifos degradation methyl parathion degradation phosphoethanolamine phosphorylase: acyltransferase polynucleotide SM255186_RS02565 SM255186_RS02565 acyltransferase large subunit cyclic-nucleotide 2'- acyltransferase 3-phosphate tryptophan nicotinamide-nucleotide a tetrahydrofolate nicotinate-nucleotide a 10- synthase/dihydrofolate glutathione biosynthesis bis(guanylyl molybdenum 6-carboxy-5,6,7,8- K-12 core type) binding transcriptional ACP synthase I: ACP synthase I: ACP synthase II: Ala carboxypeptidase: acyltransferase nucleoside- methionine lipoate biosynthesis and pyrophosphatase: SM255186_RS14365 dimethylbenzimidazole ligase: thrS an L-threonyl- inositol-1- methionine acid--CoA ligase: acyl-CoA transferase: SM255186_RS21275 FadA: fadA adenylyltransferase FadA: fadA methyltransferase G: phosphodiesterase/ FadA: fadA synthase thiamine diphosphate adenosylcobinamide- adenylyltransferase/ adenylyltransferase: formyltetrahydrofolate synthase: serine cofactor) biosynthesis tetrahydropterin regulator/O6- SM255186_RS12540 SM255186_RS12540 SM255186_RS05975 SM255186_RS03285 carboxylesterase/ carboxylesterase/ FadI: fadI diphosphate kinase: (R)-S-oxide incorporation III (Bacillus) phosphoribosyltransferase: Thr monophosphatase: parathion 3'-nucleotidase: SM255186_RS18275 [tRNA ] S-ribosylhomocysteine synthase SM255186_RS09530 synthetase SM255186_RS04200 glycogen PcnB: 2 SM255186_RS16560 subunit biosynthesis II (Bacillus) GDP ribazoletransferase: ribosylnicotinamide SM255186_RS03325 SM255186_RS12475 hydroxymethyltransferase: aminopropanol MoO - 7-carboxy-7- chlorpyrifos methyl parathion methylguanine-DNA beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- acetyl-CoA C- [+ 2 γisozymes] lipase family protein: lipase family protein: acetyl-CoA C- an N - acetyl-CoA C- SM255186_RS13380 reductase: cobT bifunctional 2 a tRNA Thr SM255186_RS13485 FdrA: fdrA L-alanyl- -D- SM255186_RS23715 acetyl-CoA C- cys glu lyase: a 5- CmoA:S-adenosyl- cmoA S- phosphotriesterase: phosphorylase: acyltransferase SM255186_RS00975 SM255186_RS07050 SM255186_RS07050 acyltransferase 1835 acyltransferase beta: trpB SM255186_RS10625 NMN kinase/transcriptional glycine tetrahydrofolate SM255186_RS18560 phosphate biosynthesis I molybdopterin deazaguanine acyl-CoA a trans-2- phosphotriesterase: phosphoethanolamine methyltransferase Ada: ACP synthase II: ACP synthase II: ACP synthase I: D-ala glutamyl-L- methylguanine D-glyceraldehyde msrB HMP-PP NaMN 5-methylbenzimidazole ribotide phosphate glutamate-- SM255186_RS14305 NADH repair hydroxyuridine 34 carboxymethyl- a 2,3,4-saturated SM255186_RS21245 a ribonucleic acid cis-vaccenyl 3'-cmp acyltransferase trp a [protein]-L- an octanoyl-[acp] α α regulator NadR: cleavage a 10- glutathione-glutaredoxin cofactor synthase myo-inositol synthetase coenzyme A long-chain-fatty- enoyl-CoA phosphotriesterase: SM255186_RS21165 SM255186_RS21165 lipid A-core- transferase CptA: cptA SM255186_RS11940 SM255186_RS05975 SM255186_RS05975 SM255186_RS12540 FadI: fadI acetate acetate an alcohol FadI: fadI in 23S rRNA FadI: fadI 3-phosphate ITP thiamine phosphate Co -[ -(5-hydroxybenzimidazolyl)]- synthase/dihydrofolate a tetrahydrofolate cysteine ligase: in tRNA L-homocysteine fatty acid a 1,2-diacyl- an (11Z)-3- a cis,cis- α-D-glucopyranose a (7Z)-3-oxo- (4Z,7Z,10Z,13Z,16Z)- lysyl-D-alanine alcohol (5Z)- FadA: fadA octanoyltransferase: β bifunctional SM255186_RS24595 system formyltetrahydrofolate a 5,10- redox reactions QueE: queE FdrA: fdrA acid--CoA ligase: SM255186_RS21165 4-nitrophenol dimethylthiophosphate phosphoethanolamine a [protein]-S- maltotetraose acetyl-CoA acetyl-CoA acetyl-CoA lauroyl-CoA (3E)-dec-3- methionine synthase: Co -adenosylcobamide 5'-phosphate adenosylcobinamide- synthase: SM255186_RS02995 thr AI-2 diethylthiophosphate sn-glycerol a guanine in DNA acyl-carrier protein oxooctadec- acyl-carrier protein delta17,29-3- 1-phosphate acyl-carrier protein hexadec-7- docosapentaenoyl-CoA dodecenoyl-CoA acetyl-CoA SM255186_RS03275 metallophosphatase/ protein a (6S)-5- methylenetetrahydrofolate bis(molybdenum NADH SM255186_RS09530 acyl-CoA (hep I) methyl-L-cysteine enoyl-CoA a [glycine-cleavage + GDP ribazoletransferase: SM255186_RS12475 7-carboxy-7- 11-enoyl-[acp] oxo-C48:2-[acp] enoyl-[acp] SM255186_RS22130 adenosylcobalamin/ NAD bifunctional formyltetrahydrofolate glutamate- L-threonine kinase: cofactor) oleoyl-CoA dehydrogenase: a (3R)-3- complex H protein] 5'-nucleotidase: H: gcvH SM255186_RS10625 bifunctional glutathione deazaguanine 4-nitrophenol paraoxon degradation alpha-ribazole methylenetetrahydrofolate a 10- SM255186_RS10830 ser a 5-(carboxymethoxy) hydroxyacyl-CoA diethylthiophosphate 6 thiamine phosphate SM255186_RS00170 formyltetrahydrofolate -cysteine molybdenum cofactor serine--tRNA ligase: SM255186_RS01665 a 2,3,4-saturated N -octanoyl-L-lysine methionine synthase: Coα-[α-(5-methylbenzimidazolyl)]- formyltetrahydrofolate tetrahydrofolate 7-cyano-7- 34 acyl-CoA a 2,3,4-saturated synthase: phosphatase: dehydrogenase/ 5-formyltetrahydrofolate ligase: gshA L-threonine 3- uridine in tRNA (3S)-3- a cis,cis- RNase G 1-arachidinoyl- D-glucopyranose 3-oxo-(5Z)- [+ 3 isozymes] SM255186_RS21925 deformylase: purU β synthase/dihydrofolate γ-L-glutamyl- guanylyltransferase: SM255186_RS04620 an L-seryl- dehydrogenase: quinoxaline-2- a cis,cis-delta19- a glycogen a (3Z)-dodec- a [ThiI sulfur-carrier a pimeloyl-[acp] trimethylamine a reduced c- 1-(18-hydroxyoleoyl)- 5-cis, 7-trans-3-oxo- (2R,3S)-2- a [protein]- (4Z)-2-oxohept- SM255186_RS03315 methenyltetrahydrofolate Co -adenosylcobamide 5'-phosphate O-phosphate (2R,4S)-2-methyl-2,4- deazaguanine fatty acyl CoA paraoxon a malonyl-[acp] delta13,25- a malonyl-[acp] a malonyl-[acp] cys a tripeptide degradation sn-glycerol FAD SM255186_RS18290 1-(β-D serine bifunctional cyclo-ligase: a reduced mobA ser hydroxyacyl-CoA ATP aryl-carrier protein tetradecadienoyl-CoA 6-phosphate dodecenoyl-CoA methylisocitrate L-threonine 4-enedioate thiamine synthase: L-cysteine [tRNA ] dihydroxydihydrofuran-3-one synthase SM255186_RS01665 acetyl-CoA C- diethylphosphate cob(II)inamide carboxyl adenylate 37-C56:2-[acp] glycogen 3-enoyl-[acp] protein]-L-cysteine methyl ester N-oxide type cytochrome sn-glycrol 3-phosphate α α cyclohydrolase FolD: folD ser phosphotriesterase: C44:2-[acp] peptidase acetyl-CoA C- substrate mRNA 3-phosphate sugar/pyridoxal acetyl-CoA C- bifunctional FAD:protein 2-oxo-hepta- Co -[ -(5-hydroxybenzimidazolyl) ribofuranosyl) hydroxymethyltransferase: methylenetetrahydrofolate SM255186_RS15690 adenosylcobalamin/alpha- glutaredoxin bis(guanylyl a tRNA acyl carrier protein: beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- cysteine pimeloyl-[acyl-carrier trimethylamine- 1-acyl-sn-glycerol- ribonuclease E: 1-acyl-sn-glycerol- phosphate thioredoxin pathway SM255186_RS12475 threonine-phosphate QueC: queC (R)-NADHX (2E,9Z)- acyltransferase SM255186_RS21165 cob(I)yrinic acid a,c-diamide phosphorylase: acyltransferase acyltransferase a [lipoyl-carrier protein] ]-Coβ-adenosylcobamide SM255186_RS13530 dehydrogenase/ ribazole phosphatase: glutathione synthetase: molybdopterin) ACP synthase I: ACP synthase I: ACP synthase II: desulfurase T: pepT protein] methyl N-oxide 3-phosphate 3-phosphate phosphate aconitate FMN 3-ene-1,7- nicotinamide a 5,10- decarboxylase: glutaredoxin 3: bifunctional ADP- a 5-(methoxycarbonylmethoxy) FadA: fadA SM255186_RS05970 SM255186_RS21245 SM255186_RS05920 N 6 -octanoyl-L-lysine thiamine- methenyltetrahydrofolate a 5,10- SM255186_RS03315 menaquinol-7 biosynthesis SM255186_RS15865 cofactor octadecenoyl-CoA diethylphosphate diethylphosphate 4-nitrophenol adenosyltransferase: peptidase B: acyltransferase: FadI: fadI phosphatase FadA: fadA hydratase 2/2- transferase dioic acid serine thiamine salvage I SM255186_RS03320 preQ uridine 34 in tRNA acyl carrier protein: SM255186_RS12540 SM255186_RS12540 SM255186_RS05975 CsdA: csdA ester esterase: reductase acyltransferase: an oxidized methylenetetrahydrofolate SM255186_RS20365 0 dependent NAD(P)H- SM255186_RS10790 maltodextrin ribonuclease G: phosphate kinase: cyclohydrolase FolD: folD methenyltetrahydrofolate α α (R)-1-amino- a 2,3,4-saturatedacetyl-CoA C-a 2,3,4-saturated SM255186_RS13435 SM255186_RS21300 TorA: torA SM255186_RS16320 acetyl-CoA C- SM255186_RS16320 YigL: yigL acetyl-CoA C- methylisocitrate ApbE: apbE hydratase: lipoyl hydroxymethyltransferase: Co -[ -(5-methylbenzimidazolyl) glutathione [+ 2 isozymes] (2R,4S)-2-methyl-2,3,3,4- hydrate dehydratase/ SM255186_RS14630 beta-ketoacyl- beta-ketoacyl- beta-ketoacyl- cysteine desulfurase: 1-[18-hydroxyoeoyl]-2- SM255186_RS17305 a 1-arachidonoyl- SM255186_RS02170 thioredoxin β 1,4-dihydroxy- fatty acyl CoA acyltransferase3-oxoacyl-CoA cob(I)yrinic acid a,c-diamide a quinoxaline-2- phosphorylase: a proteinogenic an oxidized c- acyltransferase acyltransferase dehydratase: acnB hpaH synthase: lipA SM255186_RS18560 ]-Co -adenosylcobamide 2-propanol O a protein with proline- tetrahydroxytetrahydrofuran ACP synthase II: ACP synthase II: ACP synthase I: a [ThiI sulfur- SM255186_RS08585 a dipeptide MeOH a pimeloyl-[acp] trimethylamine [18-hydroxy-lioleoyl]-sn an mRNA fragment 2-acyl-sn-glycerol sugar phosphatase: a [protein]-FMN- demethylmenaquinol- 2-naphthoate thiamine NAD(P)H-hydrate FadI: fadI adenosyltransferase: cobO AMP carboxyl-[aryl- SM255186_RS21275 amino acid type cytochrome FadA: fadA cis-2- AMP (4S)-4-hydroxy-2- thiamine acyl carrier 1,4-dihydroxy- -2-phosphate reduced L- -tRNA (S)-3-hydroxy-(9Z) SM255186_RS05975 SM255186_RS05975 SM255186_RS12540 -glycerol 3-phosphate 3-phosphate SM255186_RS12305 FadI: fadI L-threonine a [lipoyl-carrier demethylmenaquinol- 9 biosynthesis thiamine kinase: pro epimerase: a cis,cis- a cis,cis- α-D-glucopyranose a (5Z)-3-oxo- carrier protein]-S- ala (3Z,5E)-dodec- (3Z)-dec-3- methylaconitate oxoheptanedioate 6 protein activation triphosphate adenosylcobinamide carrier protein] protein]-N -[(R)- diphosphate a 5,10- 2-naphthoate cysteine residues ligase: 6 37 -octadecenoyl-CoA maltotetraose acetyl-CoA D-glucopyranose acetyl-CoA 6 biosynthesis I thioredoxin- a 5-methyltetrahydrofolate all-trans- SM255186_RS06030 glutathionylspermidine (S)-NADHX SM255186_RS23465 N -L-threonylcarbamoyladenosine acyl-carrier protein delta21,39-3- acyl-carrier protein delta15,27-3- 1-phosphate acyl-carrier protein tetradec-5- sulfanyl-L-cysteine 3,5-dienoyl-CoA enoyl-CoA dihydrolipoyl]-L-lysine methylenetetrahydrofolate 1,4-dihydroxy- polyprenyltransferase: proS an L-prolyl- an apo acyl- all-trans- disulfide reductase: geranyl diphosphate nonaprenyl thiamine biosynthesis -modified tRNA biosynthesis oxo-C58:2-[acp] oxo-C46:2-[acp] enoyl-[acp] 1,4-dihydroxy- 2-naphthoate SM255186_RS18635 [tRNA Pro ] carrier protein hexaprenyl SM255186_RS04595 biosynthesis diphosphate 1,4-dihydroxy- phosphate 4'-phosphopantetheinyl 2-naphthoate demethylmenaquinol-7 a tRNA Pro acetyl-CoA diphosphate 1,4-dihydroxy- 2-naphthoate thiamine- glutathione spermidine thr (R)-4'- a cis,cis- a cis,cis- a carboxy- an [L-cysteine phenyl-Coβ- 527 a ribonucleoside transferase: 3-oxo-(9Z)- 7,8- Nα,Nε-diacetyl-lysyl- a cytosine 32 a guanine IPP Activation/Inactivation/ thiosulfate dithioerythritol carbamoyl MEP CTP (R)-NADPHX Ap4A wound RNA 2-naphthoate polyprenyltransferase: phosphate kinase: bifunctional L-threonylcarbamoyladenylate octadecenoyl-CoA phosphopantothenoyl- delta17,35- a malonyl-[acp] delta11,23- a malonyl-[acp] dihydromonapterin cys adenylated-[ThiS D-alanyl-D-alanine desulfurase]-S- asp adenosylcobamide in 16S rRNA 2',3'-cyclic L-ornithine SM255186_RS21005 (2E,6E)-farnesyl NADH Interconversion ATP cob(II)alamin in tRNA phosphate dAMP polyprenyltransferase: a reduced SM255186_RS18635 SM255186_RS02170 glutathionylspermidine synthase type 1 TsaC: tsaC Amine and Polyamine Degradation L-cysteine C54:2-[acp] beta-ketoacyl- C42:2-[acp] beta-ketoacyl- bifunctional sulfur-carriercysteine protein] thiosulfate reductase serine-type D-Ala-D- sulfanyl-L-cysteine 2-C-methyl-D- 5'-phosphate ribosomal RNA phosphate bifunctional ADP- ATP- holo-ACP synthase: diphosphate synthase: acetyl-CoA C- bifunctional tRNA 2- aspartate adenosylcobalamin/ bifunctional 2',3'- alanine/ornithine bis(5'-nucleosyl)- SM255186_RS18635 thioredoxin demethylmenaquinol-9 thiamine amidase/synthase: threonylcarbamoyl- cob(I)yrinic acid a,c-diamide dihydroneopterin cytochrome B subunit: Ala carboxypeptidase: erythritol 4-phosphate small subunit dependent NAD(P)H- dependent SM255186_RS13640 phenylalanine- oleandomycin acyltransferase phosphopantothenoylcysteine ACP synthase I: ACP synthase I: desulfurase thiocytidine(32) carbamoyltransferase: alpha-ribazole cyclic-nucleotide 2'- racemase family PLP- tetraphosphatase demethylmenaquinol-6 SM255186_RS02190 menaquinol-7 SM255186_RS16145 adenosyltransferase: cobO aldolase/7,8- SM255186_RS10855 SM255186_RS03285 5'-deoxynucleotidase: methyltransferase G: hydrate dehydratase/ RNA a holo acyl- geranyl diphosphate activation/inactivation AMP synthase: FadA: fadA allantoin degradation IV (anaerobic) SM255186_RS12540 SM255186_RS12540 CsdA: csdA synthetase SM255186_RS23930 cytidylyltransferase: phosphatase: phosphodiesterase/ dependent enzyme: (symmetrical): apaH glutathionylspermidine -tRNA ligase: L-carnitine degradation I putrescine degradation I decarboxylase/ SM255186_RS12290 carrier protein diphosphate phe SM255186_RS06470 superpathway of N-acetylglucosamine, ethanolamine utilization cob(I)yrinic acid a,c-diamide dihydroneopterin thiosulfate reductase [+ 2 isozymes] SM255186_RS14870 7 SM255186_RS19270 NAD(P)H-hydrate helicase SM255186_RS08700 (L-threonylcarbamoyl) phosphopantothenate-- beta-ketoacyl- beta-ketoacyl- cysteine desulfurase: TtcA:an [L-cysteinettcA SM255186_RS23935 4-(cytidine 5'- SM255186_RS03315 an N - 3'-nucleotidase: SM255186_RS12440 acetyl-CoA C- α ε a 2-thiocytosine 32 β oleandomycin N-acetylmannosamine and N- adenosyltransferase: epimerase: PhsA: phsA N ,N -diacetyl- N-carbamoyl- phenyl-Co - 527 epimerase: RhlB: rhlB SM255186_RS08705 an L-phenylalanyl- adenylate acyltransferase (S)-(+)-allantoin cysteine ligase CoaBC: coaBC ACP synthase II: ACP synthase II: SM255186_RS08585 4,5-cis-dihydroxy- D-ala desulfurase]- diphospho)-2-C- methylguanine SM255186_RS23715 D-ornithine ADP acetylneuraminate degradation L-carnitine putrescine SM255186_RS10790 SM255186_RS16485 sulfite lysyl-D-alanine in tRNA L-aspartate 2'-deoxyadenosine adenosylcobamide a ribonucleoside SM255186_RS23465 an unwound RNA Phe ethanolamine 4'-phosphopantetheine SM255186_RS05975a cis,cis- SM255186_RS05975a cis,cis- L-cysteine methyl-D-erythritol in 16S rRNA [tRNA ] FadI: fadI triphosphate adenosylcobalamin 6-(hydroxymethyl) AMP ala a thiocarboxy- 1,2-dithiacyclohexane Phe N-acetylneuraminate putrescine glycolaldehyde 3'-phosphate (S)-NADPHX a tRNA acyl-carrier protein delta19,37-3- acyl-carrier protein delta13,25-3- -7,8-dihydropterin [ThiS-Protein] glucosyl- (7Z)-hexadecenoyl-CoA N-acetylneuraminate ethanolamine aminotransferase: ygjG an N 6 -L- oxo-C56:2-[acp] oxo-C44:2-[acp] oleandomycin lyase: nanA ammonia-lyase: 4-aminobutanal threonylcarbamoyladenine 37 acyl-CoA N-acetyl-D- multidrug resistance allantoate SM255186_RS13010 in tRNA mannosamine Amino Acid Biosynthesis protein MdtM: dehydrogenase: eutB L-carnitinyl-CoA aminobutyraldehyde a cis,cis- an apo-[LYS2 L- core 1915 4-(cytidine 5'- adenosine 1-myristoyl- a [lipoyl-carrier superpathway of L- adenosylcobinamide- phenyl ribotide a cis,cis-delta9,21- sn-glycero-3- M-antigen a pseudouridine a ribonucleoside superpathway of aromatic amino acid biosynthesis L-histidine biosynthesis superpathway of L-lysine, L-threonine and L-methionine biosynthesis I superpathway of L-methionine biosynthesis (transsulfuration) superpathway of branched chain amino acid biosynthesis L-arginine biosynthesis I (via L-ornithine) L-methionine biosynthesis II (plants) methionine-- SM255186_RS01665 allantoate N-acetylmannosamine carnitinyl-CoA a cis-vaccenoyl-[acp] sn-glycerol 3-phosphate delta15,33- a malonyl-[acp] a malonyl-[acp] 2-aminoadipyl- coenzyme A a purine diphospho)-2-C- (S)-dihydroorotate 2',3'-cyclic sn-glycerol MEP protein]-N 6 -[(R) isoleucine biosynthesis I met SM255186_RS24335 dehydrogenase: patD GDP phosphate phosphoethanolamine oligosaccharide- in 23S rRNA arsenate diphosphate dGMP a stearoyl-[acp] GTP kinase: acetaldehyde dehydratase: C40:2-[acp] (variant) monomer 23S rRNA ribonucleoside -dihydrolipoyl]- tRNA ligase: [+ 2 isozymes] (2E,7Z)- amidohydrolase: L-carnitine CoA- glycerol-3-phosphate adenosylcobinamide- C52:2-[acp] beta-ketoacyl- beta-ketoacyl- carrier-protein] holo-ACP synthase: glycerophosphodiester lipid A (E. coli ribonucleoside- methyl-D-erythritol4-diphosphocytidyl- monophosphatebifunctional 2',3'- 3-phosphate1-acyl-sn-glycerol- 1-deoxy-D-xylulose- D-erythrose an L-methionyl- SM255186_RS17140 SM255186_RS00355 undecaprenyl (pseudouridine(1915)- purine-nucleoside dihydroorotase: beta-ketoacyl- L-lysine oxaloacetate oxaloacetate pyruvate SM255186_RS11420 hexadecenoyl-CoA SM255186_RS02750 transferase: 4-aminobutanoate acyltransferase: plsY GDP ACP synthase I: ACP synthase I: SM255186_RS13640 phosphodiesterase: K-12 core type) diphosphate reductase: 2C-methyl-D- cyclic-nucleotide 2'- 3-phosphate 5-phosphate diguanylate 4-phosphate PRPP oxaloacetate thr glu L-homoserine [elongator glucosyl- N-end rule pathway I (prokaryotic) N-acetyl-D- diphosphate phosphorylase: 5'-deoxynucleotidase: SM255186_RS05785 ACP synthase I: dihydrolipoyl aspartate ribazoletransferase: SM255186_RS12540 SM255186_RS12540 SM255186_RS21150 O-antigen(no GlcNAc) N(3))-methyltransferase SM255186_RS12010 reductoisomerase: cyclase elongator Met oleandomycin N-acetylglucosamine SM255186_RS00365 glycerol-3-phosphate 4'-phosphopantetheinyl erythritol kinase: phosphodiesterase/ acyltransferase: dehydrogenase: aspartate acetolactate synthase tRNA ] (S)-ureidoglycine mannosamine ligase deoD SM255186_RS12290 SM255186_RS12540 aminotransferase: 3-deoxy-7- ATP Met SM255186_RS10625 glycerophosphodiester 3 RlmH: rlmH SM255186_RS12015 SM255186_RS01120 AdrA: adrA aspartate aminotransferase: serine/threonine N-acetylglutamate tRNA leucyl/phenylalanyl- degradation II 1-O-acyltransferase: beta-ketoacyl- beta-ketoacyl- transferase: di-trans,octa-cis an N - a 2'- 2-phospho-4-(cytidineSM255186_RS09335 N-carbamoyl- 3'-nucleotidase: 1-myristoyl-2-SM255186_RS16320 1-deoxy-D- lpdA phosphoheptulonate phosphoribosyltransferase: aminotransferase: large subunit: homoserine kinase: 6-phosphate γ-butyrobetainyl- crotonobetainyl- phenyl-Coβ- RfaL: rfaL ribose-1-arsenate a purine base a 3-oxoicosanoyl- a [lipoyl-carrier SM255186_RS04790 SM255186_RS04790 tRNA--protein (S)-ureidoglycine SM255186_RS22055 ACP synthase II: ACP synthase II: SM255186_RS21005 phosphodiesterase: methylpseudouridine 1915 deoxyribonucleoside SM255186_RS23715 [+ 5 isozymes] dehydratase: synthase: SM255186_RS00015 (S)-3-hydroxy-(7Z) N-acetylmannosamine- N-acetyl-D- a holo-[LYS2 L- -undecaprenyl E. coli M 5'-diphospho)-2-C- L-aspartate palmitoleoyl- xylulose 5- protein]-N 6 - synthase AroG: SM255186_RS10915 SM255186_RS04790 SM255186_RS19880 acetyl-CoA ethanol CoA CoA 1-cis-vaccenoyl-sn- GMP adenosylcobamide SM255186_RS12035 LPS 2'-deoxyguanosine [acp] c-di-GMP asp SM255186_RS16680 SM255186_RS15250 transferase: aminohydrolase: acyl-carrier protein SM255186_RS05975a cis,cis- SM255186_RS05975a cis,cis- 2-aminoadipyl- 3',5'-ADP diphosphate in 23S rRNA 5'-diphosphate methyl-D-erythritol 3'-AMP sn-glycerol phosphate SM255186_RS03860 [+ 2 isozymes] a [protein] -hexadecenoyl-CoA 6-phosphate glucosamine 5'-phosphate sn-glycerol lipoyl-L-lysine 1-(5-phospho- asp SM255186_RS04580 SM255186_RS02745 N-acetyl-D- glycerol-3-phosphate 3-phosphate asp threonine N-acetyl-L- O-phospho-L-homoserine oleandomycin an N-terminal N-terminal L- 2-epimerase: phosphate acyl-carrier protein delta17,35-3- acyl-carrier protein delta11,23-3- carrier-protein] ethanolamine bifunctional aspartate [+ 2 isozymes] β-D-ribosyl)-ATP lysine- glucosamine kinase: 3-phosphate (S)-2-acetolactate ammonia- glutamate Lys arginyl-[protein] SM255186_RS05585 acetyltransferase: oxo-C54:2-[acp] oxo-C42:2-[acp] 3-deoxy-D-arabino- a tRNA -tRNA leucyl-L-arginine (S)-ureidoglycolate SM255186_RS06090 kinase/homoserine bifunctional aspartate bifunctional aspartate lyase, cystathionine N-acetyl-D- SM255186_RS12330 N-acetyl-D- heptulosonate ligase: lysS crotonobetainyl-CoA dehydrogenase I: kinase/homoserine kinase/homoserine ketol-acid biosynthetic: acetylglutamate gamma-synthase: an L-lysyl- 3-oxo-(7Z)- ureidoglycolate ureidoglycolate glucosamine glucosamine 7-phosphate leucyl/phenylalanyl- phosphate a mature peptidoglycan 4-methylphenyl a cis,cis- 1-stearoyl- an [amino group carrier protein]- a 1-palmitoyl-2- DNA with adenine:7,8- 18 guanosine a 1-acyl-sn 2552 SM255186_RS00010 dehydrogenase I: reductoisomerase: kinase: argB [tRNA Lys ] hexadecenoyl-CoA 6-phosphate 6-phosphate dehydrogenase: adenosylcobinamide- a cis,cis-delta7,19- an apo-[aryl- 4-hydroxy- a [glutamine- trimethylamine a reduced a guanosine uridine 3-dehydroquinate 1-(5-phospho-β- dehydrogenase I: ilvA SM255186_RS18585 dehydrogenase: dehydrogenase: acetyltransferase: pta ribotide delta13,31- a malonyl-[acp] a malonyl-[acp] coenzyme A C-terminal-γ-(L-glutamate 5- acyl-sn-glycero-3- lipid II dihydro-8- glutathione 2,2-dichloroacetate 2',3'-cyclic -glycerol 3- cyclic-AMP Pentose Phosphate Pathways tRNA--protein SM255186_RS00370 (meso-diaminopimelate a palmitoyl-[acp] sn-glycerol A 2-nonenal in tRNA in 23S rRNA acyl-carrier protein [+ 2 isozymes] SM255186_RS00010 SM255186_RS00010 SM255186_RS17875 lys acetyl-CoA C- SM255186_RS02755 SM255186_RS02755 N-acetylglucosamine- N-acetylglucosamine- GDP C38:2-[acp] carrier protein] synthetase]- ATP N-oxide TorY protein synthase: D-ribosyl)-AMP (2R)-2,3- (2Z)-2-aminobut- N-acetylglutamyl- transferase: containing) phosphate C50:2-[acp] beta-ketoacyl- beta-ketoacyl- holo-ACP synthase: 3-phosphate semialdehyde-2-yl)-L-glutamate phosphocholine oxoguanine mismatchadenine DNA glutathione S- glutathione S- tRNA monophosphate phosphate 23S rRNA 3',5'-cyclic-AMP malonyl [+ 2 isozymes] L-cystathionine acyltransferase 6-phosphate acetyl phosphate 6-phosphate lytic transglycosylase: adenosylcobinamide- 1-acyl-sn-glycerol- N-acetyl-gamma- lipid IV(A) L-tyrosine glutamine-synthetase trimethylamine- bifunctional 2',3'- 1-acyl-sn-glycerol- L-aspartyl- SM255186_RS21420 [+ 2 isozymes] dihydroxy-3- 2-enoate phosphate SM255186_RS04580 a [protein] N-carbamoyl- SM255186_RS13640 transferase: transferase: (guanosine(18)-2'-O) (uridine(2552)-2'-O) bifunctional pentose phosphate pathway (non-oxidative branch) an N-terminal FadA: fadA deacetylase: deacetylase: SM255186_RS22635 GDP ACP synthase I: ACP synthase I: 3-phosphate glutamyl-phosphate palmitoyltransferase glycosylase: adenylyltransferase: N-oxide cyclic-nucleotide 2'- 3-phosphate phosphodiesterase: CoA-ACP 4-phosphate methylbutanoate N-terminal L- 2-oxoglycine SM255186_RS20465 SM255186_RS20465 -methyltransferase -methyltransferase: phosphoribosyl- L-aspartyl-4-phosphate N-acetyl-gamma- L-lysyl-[protein] SM255186_RS03480 acetate/propionate SM255186_RS03480 [+ 4 isozymes] ribazoletransferase: SM255186_RS12540 SM255186_RS12540 4'-phosphopantetheinyl acyltransferase: reductase: PagP: SM255186_RS15955 a [glutamine reductase phosphodiesterase/ acyltransferase: SM255186_RS16370 transacylase: 3-dehydroquinate L-aspartyl-4-phosphate leucyl-L-lysine acetyl-CoA C- a mature peptidoglycan SM255186_RS16460 AMP cyclohydrolase/ cystathionine beta-lyase: D-ribulose 4-aminobutanoate SM255186_RS10625 transferase: SM255186_RS16320 an [amino group carrierSM255186_RS18495 protein]- an apurinic site [+ 3 isozymes] synthetase]-O TorA: torA [+ 3 isozymes] TrmH: trmH 3'-nucleotidase: SM255186_RS16320 a 2'-O- rlmE fabD aspartate- glutamyl-phosphate acyltransferase D-glucosamine family kinase: D-glucosamine with (L-alanyl-γ-D- a mature peptidoglycan beta-ketoacyl- beta-ketoacyl- 1-stearoyl- SM255186_RS03240 adenine (glutathion-S- a 2'-O- a 1-acyl-2- 4-methylphenyl-Co a 2-acyl-sn-glycero- 4 an oxidized 18 2552 semialdehyde 3-dehydroquinase: phosphoribosyl-ATP reductase: SM255186_RS16250 his 5-phosphate SM255186_RS10825 degradation II ACP synthase II: ACP synthase II: SM255186_RS21005 C-terminal-γ-(5-phospho- lipid II within DNA yl)-4-hydroxy- -(5'-adenylyl) trimethylamine glyoxylate methylguanosine SM255186_RS23715 arachidonoyl- methyluridine AMP a malonyl-[acp] aspartate-semialdehyde FadI: fadI 6-phosphate 6-phosphate glutamyl-meso-2,6- strand (non- β 2-palmitoyl- B diphosphatase HisIE: aspartate-semialdehyde histidine--tRNA ligase: GMP -adenosylcobamide a holo-[aryl- acyl-carrier protein 3-phosphocholine TorY protein dehydrogenase: SM255186_RS08640 dehydrogenase: asd 2-iminobutanoate SM255186_RS18495 diaminopimeloyl-D- reducing terminus) SM255186_RS05975a cis,cis- SM255186_RS05975a cis,cis- 3',5'-ADP sn-glycerol L-glutamyl)-L-glutamate 2-nonenal -L-tyrosine in tRNA 3'-GMP sn-glycerol in 23S rRNA dehydrogenase: asd 3-methyl-2- SM255186_RS13360 an L-histidyl- [+ 2 isozymes] 5'-phosphate carrier protein] asd SM255186_RS10950 N-acetyl-L- ribose-5- ribulose-phosphate (5Z)-tetradecenoyl-CoA carbamoyl 4-aminobutanoate 3-phosphate aspartate-semialdehyde oxobutanoate 2-aminoprop-2-enoate His oxamate 4-aminobutanoate alanine) tetrapeptide acyl-carrier protein delta15,33-3- acyl-carrier protein delta9,21-3- 3-phosphate 3-dehydroshikimate 1-(5-phospho-β-D-ribosyl)- aspartate-semialdehyde superpathway of L-homoserine and L-methionine biosynthesis glutamate 5- L-homocysteine [tRNA ] phosphate 3-epimerase: acetate 4-aminobutyrate- aspartate-semialdehyde dehydrogenase: His phosphate degradation III oxo-C52:2-[acp] oxo-C40:2-[acp] 5-[(5-phosphoribosylamino) dehydrogenase: semialdehyde a tRNA isomerase SM255186_RS21435 acyl-CoA α-D-glucosamine α-D-glucosamine -2-oxoglutarate dehydrogenase: shikimate 5- SM255186_RS12495 2-isopropylmalate branched chain amino 5-methyltetrahydropteroyltriglutamate- carbamoyl- methylideneamino]imidazole- SM255186_RS12495 succinylornithine RpiA: rpiA ribulose-phosphate dehydrogenase: 6-phosphate 6-phosphate transaminase: SM255186_RS12495 synthase: acid aminotransferase: phosphate synthase: 4-aminobutanoate dehydrogenase: 4-carboxamide asp 2-oxobutanoate aminotransferase: - homocysteine methyltransferase: SM255186_RS01665 SM255186_RS14155 a nascent a 1-acyl-2-lyso- a cis,cis- DNA combined with dehydro(indole- a 3,5,7,9,11,13,15- a 6,7- a cytidine 1402 guanosine 2251 L-aspartate 4-semialdehyde 3-epimerase: glucosamine-6- glucosamine-6- succinate 4-aminobutyrate- a cis,cis-delta5,17- AsbD acyl- 5-hydroxybenzimidazole glutathione trimethylamine a reduced a ribonucleoside a holo [PedD acyl- L-aspartate 4- SM255186_RS19370 L-aspartate 4-semialdehyde SM255186_RS00595 SM255186_RS17905 SM255186_RS17575 SM255186_RS00335 peptidoglycan (meso delta11,29- a malonyl-[acp] a malonyl-[acp] coenzyme A exogenous DNA to form 1-methyl-dAMP 2-oxoglutarate hepta-oxo- a myristoyl-[acp] asp a protein 1-(5-phosphoribosyl) SM255186_RS08900 2-iminopropanoate D-ribose 5- SM255186_RS18690 (2E,5Z)- phosphate deaminase: phosphate deaminase: phosphatidylethanolamine ribotide phosphate 3-yl)acetonitrile dihydropteridine in 16S rRNA 3'-phosphate in 23S rRNA bifunctional aspartate acetolactate synthase SM255186_RS00340 semialdehyde -2-oxoglutarate C36:2-[acp] carrier protein glutathione S- DNA oxidative N-oxide TorC protein carrier protein] semialdehyde -5-((5- hydrogencarbonate methionine synthase: glycine--tRNA phosphate tetradecenoyl-CoA SM255186_RS03485 SM255186_RS03485 -DAP containing)lytic transglycosylase: multifunctional acyl- C48:2-[acp] beta-ketoacyl- beta-ketoacyl- holo-ACP synthase: a recombinational junctioncrossover junction adenosylcobalamin/ hexadecanoyl-[PKS-acp] trimethylamine- oxygen-insensitive 16S rRNA bifunctional 2',3'- 23S rRNA ATP-dependent malonyl shikimate bifunctional aspartate (2S)-2- large subunit: N-acetyl-L- gly transaminase: aldo/keto reductase: beta-ketoacyl- aspartate/glutamate kinase/homoserine SM255186_RS21925 [+ 2 isozymes] NADP-dependent CoA thioesterase ACP synthase I: ACP synthase I: alpha-ribazole transferase: demethylase NAD(P)H (cytidine(1402)-2'-O) (guanosine(2251) bifunctional aspartate phosphoribosylamino) val SM255186_RS19880 ornithine ligase: glyQ D-xylulose SM255186_RS14155 SM255186_RS22635 SM255186_RS13640 endodeoxyribonuclease N-oxide cyclic-nucleotide 2'- Clp protease CoA-ACP 4-hydroxy- bifunctional aspartate kinase/homoserine dehydrogenase I: isopropylmalate carbamoyl- F6P F6P succinate-semialdehyde I/protease I/ SM255186_RS20465 AlkB: alkB SM255186_RS00720 ACP synthase I: nitroreductase: -methyltransferase: -2'-O)- racemase: kinase/homoserine shikimate kinase: methylideneamino) SM255186_RS20620 5-phosphate succinate [+ 4 isozymes] SM255186_RS12540 SM255186_RS12540 4'-phosphopantetheinyl RuvC: ruvC phosphatase: reductase phosphodiesterase/ proteolytic subunit: transacylase: tetrahydrodipicolinate dehydrogenase I: SM255186_RS00010 3-isopropylmalate [+ 2 isozymes] acetylornithine Gly glyoxylate cycle carbamate dehydrogenase I: a mature peptidoglycan [+ 3 isozymes] SM255186_RS12540 SM255186_RS15395 imidazole-4- kinase/homoserine phosphate synthase: met a glycyl-[tRNA ] semialdehyde a nascent lysophospholipase L1: transferase: SM255186_RS03315 [+ 3 isozymes] TorA: torA SM255186_RS02970 SM255186_RS16780 3'-nucleotidase: methyltransferase fabD dehydrogenase I: SM255186_RS21415 SM255186_RS00010 with (L-alanyl-γ-D- beta-ketoacyl- beta-ketoacyl- Holliday junction (2S,3R,4S,5R)-2-(5-hydroxy- (glutathion-S-yl)(1H- 9-hydroxy-3,5,7,11,13,15- a 5,6,7,8- a 2'-O- SM255186_RS02340 a malonyl- synthase: dehydrogenase I: [+ 2 isozymes] dehydratase: (S)-2-aceto-2- SM255186_RS00335 deacetylase: Gly transketolase: SM255186_RS14150 peptidoglycan (meso SM255186_RS02650 succinate formaldehyde dAMP a 3-oxohexadecanoyl- an oxidized RlmB: rlmB SM255186_RS00010 shikimate kinase: carboxamide isomerase: pyruvate a tRNA ACP synthase II: ACP synthase II: SM255186_RS21005 resolvase RuvX: ruvX 1,3-benzodiazol-1-yl)-5- hexaoxohexadecanoyl- trimethylamine methylcytidine 1402 SM255186_RS23715 2-O- D-aspartate a peptide [PedD acyl- SM255186_RS13185 SM255186_RS00010 bifunctional aspartate leuD leuC hydroxybutanoate SM255186_RS00340 SM255186_RS18500 SM255186_RS12345 (3E,5Z)-tetradeca- (S)-3-hydroxy-(5Z) glutamyl-meso-2,6- -DAP containing) sn-glycero-3- resolution of recombinational indol-3-yl)acetonitrile [acp] TorC protein tetrahydropteridine SM255186_RS02000 SM255186_RS10940 succinate succinate a carboxylate SM255186_RS05975 SM255186_RS05975 a holo-[AsbD acyl- (hydroxymethyl)oxolane-3,4-diol [PKS-acp] in 16S rRNA a ribonucleoside methylguanosine 2251 carrier protein] bifunctional aspartate kinase/homoserine [+ 2 isozymes] acetyl-CoA glyoxylate 3,5-dienoyl-CoA -tetradecenoyl-CoA diaminopimeloyl-D- phosphoethanolamine a cis,cis- a cis,cis- 3',5'-ADP junction formation bifunctional aspartate L-aspartyl-4-phosphate ketol-acid carbamoyl with GlcNAc terminus carrier protein] in 23S rRNA kinase/homoserine phosphoribulosylformimino- dehydrogenase II: 2-isopropylmaleate L-ornithine alanine) tetrapeptide acyl-carrier protein delta13,31-3- acyl-carrier protein delta7,19-3- of two intact strands shikimate 3-phosphate (2S,4S)-4-hydroxy-2,3,4,5- kinase/homoserine reductoisomerase: phosphate D-sedoheptulose D-glyceraldehyde malate synthase A: CO succinate dehydrogenase II: AICAR-phosphate SM255186_RS18580 2 oxo-C50:2-[acp] oxo-C38:2-[acp] tetrahydrodipicolinate dehydrogenase II: aspartate-semialdehyde 3-isopropylmalate SM255186_RS17875 isocitrate lyase: aceA SM255186_RS18580 methionine-- 7-phosphate 3-phosphate SM255186_RS21905 3-phosphoshikimate 1- 4-hydroxy- SM255186_RS18580 dehydrogenase: asd dehydratase: (R)-2,3-dihydroxy- met (3E,5Z)- 3-oxo-(5Z)- imidazole glycerol L-homoserine tRNA ligase: α carboxyvinyltransferase: tetrahydrodipicolinate aspartate-semialdehyde leuD leuC 3-methylpentanoate transaldolase: tal tetradecadienoate tetradecenoyl-CoA 4-amino-4-deoxy- - an sn-glycero-3- 1-myristoyl- 1-stearoyl- all-trans- 1-chloro-2,4- a guanine 34 adenine 1518 / (3R,5S)-3- L-homoserine SM255186_RS11420 an L-methionyl- a cis,cis-delta3,15- 1,4-dihydroxy- glutathione queuine an isocitrate roseoflavin NaMN a holo [PedN acyl- aroA phosphate reductase: an acetyl-[acp] a malonyl-[acp] L-arabinopyranosyl phospho-N-(acyl) a malonyl-[acp] a palmitoleoyl-[acp] sn-glycerol a stearoyl-[acp] sn-glycerol tridecaprenyl dinitrobenzene 1519 a dodecanoyl-[acp] an octanoyl-[acp] hydroxy-1- met a protein dehydrogenase: (2R,3S)-3- Met transaldolase: tal acetyl-CoA C- lipid IV (E. coli) in tRNA adenine in 16S rRNA [initiator tRNA ] A C34:2-[acp] 2-naphthoate dehydrogenase carrier protein] synthase: hisH SM255186_RS00325 L-homoserine beta-ketoacyl-ACP synthase ditrans,octacis- ethanolamine beta-ketoacyl- 3-phosphate 3-phosphate diphosphate glutathione S- tRNA guanosine(34) ribosomal RNA bifunctional riboflavin bifunctional pyrroline-5- 5-enolpyruvoyl- homoserine O- SM255186_RS12495 isopropylmalate asp L-citrulline Met acyltransferase Nucleoside and Nucleotide Degradation glycerophosphodiester 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1,4-dihydroxy- bifunctional isocitrate malonyl homoserine kinase: SM255186_RS10945 initiator tRNA undecaprenyl4-amino-4-deoxy- phosphate transferase: transglycosylase Tgt: small subunit beta-ketoacyl- beta-ketoacyl- metallophosphatase/ carboxylate N-acetylglutamate shikimate 3-phosphate succinyltransferase: 3-isopropylmalate D-erythrose D-threo-isocitrate (S)-malate FadA: fadA I: SM255186_RS12540 phosphodiesterase: ACP synthase I: 3-phosphate 3-phosphate 2-naphthoate dehydrogenase kinase/FAD synthetase: tail-specific protease: CoA-ACP SM255186_RS00015 (S)-2,3,4,5-tetrahydrodipicolinate F6P SM255186_RS20465 methyltransferase A: ACP synthase I: ACP synthase I: 5'-nucleotidase: pyrroline-5- synthase: L-aspartate 4-semialdehyde (S)-3-methyl-2- 4-phosphate beta-ketoacyl-ACP synthase L-arabinose lipid SM255186_RS21150 SM255186_RS12540 acyltransferase: acyltransferase: polyprenyltransferase: SM255186_RS02095 kinase/phosphatase: SM255186_RS00230 SM255186_RS09660 transacylase: D-erythro-1- homoserine O- homoserine kinase: SM255186_RS21900 dehydrogenase: acetyl-CoA C- purine nucleotides degradation II (aerobic) SM255186_RS12540 SM255186_RS12540 carboxylate reductase: SM255186_RS15250 chorismate synthase: oxopentanoate bifunctional superpathway of purine deoxyribonucleosides degradation A transferase: [+ 3 isozymes] 34 6 SM255186_RS004601518 SM255186_RS00170 O-phospho- AICAR 2,3,4,5- cys leuB argininosuccinate transketolase: superpathway of pyrimidine II: SM255186_RS05975 glycerophosphodiester beta-ketoacyl- SM255186_RS163201-myristoyl-2- SM255186_RS163201-stearoyl-2- SM255186_RS18635 a queuosine N -dimethyladenine a phosphorylatedSM255186_RS21915 roseoflavin SM255186_RS01990 a malonyl[PedNfabD SM255186_RS12570 (imidazol-4- succinyltransferase: SM255186_RS00015 acyltransferase 2,4-dinitrophenyl- guanine a 3-oxotetradecanoyl- a 3-oxodecanoyl- N-acetyl-L- bifunctional aspartate branched chain amino aconitate hydratase SM255186_RS12135 6 1519 [+ 3 isozymes] a peptide L-homoserine yl)-glycerol tetrahydropyridine- (2S)-2-isopropyl- synthase: SM255186_RS12345 FadI: fadI deoxyribonucleosides degradation an acetoacetyl-[acp] acyl-carrier protein di-trans,octa-cis- phosphodiesterase: ACP synthase II: palmitoleoyl- stearoyl-sn DMKH2-13 S-glutathione in tRNA /N -dimethyladenine isocitrate 5'-phosphate β acyl-carrier SM255186_RS21900 kinase/homoserine acid aminotransferase: Fatty Acid and Lipid Biosynthesis 2/2-methylisocitrate lipid II acyl-carrier protein acyl-carrier protein [acp] [acp] -D- Hyp methionine 3-phosphate 2,6-dicarboxylate N- O-succinyl-L-homoserine 3-oxosuccinate SM255186_RS16910 [+ 2 isozymes] undecaprenyl phosphate A SM255186_RS12035 SM255186_RS05975a cis,cis- sn-glycerol -glycerol 3- in 16S rRNA dehydrogenase protein] threonine synthase: chorismate cys dehydrogenase I: SM255186_RS17905 (3Z)-dodec- AMP 2'-deoxycytidine ribosylnicotinate succinyltransferase: dapD dehydratase: acnB 2'-deoxyguanosine sn-glycerol an N- 3-phosphate phosphate bifunctional O-phospho-L-homoserine L-arginine biosynthesis II (acetyl cycle) D-glyceraldehyde 3-enoyl-CoA IMP acyl-carrier protein delta5,17-3- SM255186_RS00020 SM255186_RS00010 L-arginino- palmitate biosynthesis II (bacteria and plant cytoplasm) [+ 2 isozymes] 3-phosphate acylethanolamine histidinol- O-succinyl-L-homoserine superpathway of lipopolysaccharide biosynthesis stearate biosynthesis 3-phosphate bifunctional UDP- cytidine deaminase: 2'-deoxyadenosine oxo-C36:2-[acp] chorismate mutase: N-succinyl-2-amino-6-ketopimelate cystathionine bifunctional aspartate ile succinate phosphatidylserine and phosphatase/ threonine synthase: N-acetylglutamyl- II (bacteria and plants) cis-aconitate acetyl-CoA oxaloacetate sugar hydrolase/ SM255186_RS11565 thr SM255186_RS09110 gamma-synthase: kinase/homoserine 4-methyl-2- a (3R)-3- phosphatidylethanolamine IMP imidazoleglycerol- SM255186_RS00020 argininosuccinate lyase: phosphate N-acetyl-gamma- purine-nucleoside SM255186_RS18585 an acetoacetyl-[acp] biosynthesis I 5'-nucleotidase dehydrogenase: thymidine 1-palmitoyl- all-trans- a cis-delta19- a phosphorylated a [pyruvate dehydrogenase 966 an [RNA]-3'- an oxidized [+ 2 isozymes] cystathionine dehydrogenase II: oxopentanoate UDP-N-acetyl- hydroxytetradecanoyl- bifunctional (2E)-dodec- a lipid II a cis-delta19- adenosylcobinamide- 1,4-dihydroxy- a guanine a [release factor]- phosphate SM255186_RS18485 glutamyl-phosphate 2'-deoxyuridine adenosine deaminase: phosphorylase: an acyl-[acyl- a 2-acyl-1-lyso- pristanate α-ribazole glutathione methylmercury 1-methyl-dATP 2-oxoglutarate E2 protein] N 6 - nitroaromatic a holo [BryP acyl- serine/threonine anthranilate SM255186_RS18580 α a palmitoyl-[acp] aconitate hydratase periplasmic precursor: guaB a malonyl-[acp] a palmitoleoyl-[acp] sn-glycerol GDP decaprenyl 37-methoxy-38- a lignoceroyl-[acp] isocitrate in 16S rRNA ribunucleoside- L-glutamine a protein dehydratase gamma-synthase: branched chain amino -D-glucosamine [acp] a CDP-diacylglycerol 2-enoyl-CoA thymidine deoD carrier protein] phosphatidylethanolamine serine-type D-Ala-D- C38:1-[acp] 2-naphthoate carrier protein] thr reductase: beta-ketoacyl- SM255186_RS02585 GMP SM255186_RS08120 long-chain-fatty- beta-ketoacyl- 3-phosphate adenosylcobinamide- diphosphate glutathione S- DNA oxidative methyl-C57:1-[acp] dehydrogenase dihydrolipoyl-L-lysine 16S rRNA 2',3'- peptide chain compound dehydratase: SM255186_RS18585 acid aminotransferase: CDP-diacylglycerol--serine 2/2-methylisocitrate phosphorylase: purine-nucleoside bifunctional 2- 1-acyl-sn-glycerol- 1,4-dihydroxy- bifunctional isocitrate malonyl bifunctional anthranilate prephenate HisB: hisB N-succinyl-L,L-2,6-diaminopimelate L-cystathionine arg SM255186_RS18495 ACP synthase I: Ala carboxypeptidase: acid--CoA ligase: GDP transferase: demethylase cyclopropane fatty acyl beta-ketoacyl- dihydrolipoyl (guanine(966)-N(2)) cyclophosphate release factor NAD(P)H beta-barrel assembly- SM255186_RS16680 L-homoserine L-cysteine biosynthesis O-phosphatidyltransferase: dehydratase: acnB [+ 3 isozymes] XMP acylglycerophosphoethanolamine ACP synthase I: 3-phosphate 2-naphthoate dehydrogenase RNA 2',3'-cyclic CoA-ACP synthase glutamate 3-(imidazol-4- SM255186_RS17905 citrate synthase: deoA phosphorylase: SM255186_RS03285 SM255186_RS09530 SM255186_RS20465 AlkB: alkB phospholipid synthase: ACP synthase I: dehydrogenase: nitroreductase: enhancing protease: VI (from L-methionine) a (3R)-3- SM255186_RS12540 SM255186_RS13765 [+ 2 isozymes] bifunctional UDP- uridine phosphorylase: purine-nucleoside acyltransferase/acyl-ACP SM255186_RS12540 acyltransferase: ribazoletransferase: polyprenyltransferase: kinase/phosphatase: -methyltransferase: N(5)-glutamine transacylase: threonine amidotransferase component yl)-2-oxopropyl succinyl-diaminopimelate N-acetylglutamate UDP-3-O-[(3R)-3- a 3-oxooctadecanoyl- SM255186_RS03725 deoD [+ 2 isozymes] SM255186_RS08315 SM255186_RS12540 lpdA phosphodiesterase: SM255186_RS08935 SM255186_RS13220 adenosine sugar hydrolase/ SM255186_RS17560 thymine 2'-deoxyinosine phosphorylase: acyl-CoA synthetase SM255186_RS10625 [+ 3 isozymes] 2 SM255186_RS21060 methyltransferase: ammonia- bifunctional chorismate bifunctional chorismate phosphate desuccinylase: L-cystathionine homoserine O- leu synthase: acetylglutamate hydroxybutanoyl- [acp] a 3-sn-phosphatidyl-L-serine (S)-3- bifunctional UDP- synthetase: SM255186_RS15350 a N-acetylglucosamine--N- beta-ketoacyl- SM255186_RS163201-palmitoyl-2- SM255186_RS18635 SM255186_RS21915 a [pyruvate dehydrogenase an N - SM255186_RS00995 a reduced a malonyl-fabD TrpG/anthranilate cystathionine beta-lyase: hydroxymyristoyl]-N- deoD methylmercury- succinate formaldehyde dATP a cis-methoxy- a 3-oxohexacosanoyl- an [RNA]-3'- prmC succinyltransferase: kinase: argB N-acetyl-L- 5'-nucleotidase sugar hydrolase/ an L-1- FdrA: fdrA an isocitrate 6 966 lyase, mutase/prephenate mutase/prephenate SM255186_RS13155 met SM255186_RS15250 [acp] hydroxydodecanoyl-CoA acyl-carrier protein D-ala acetylmuramyl-(tetrapeptide) ACP synthase II: DMKH2-10 methylguanine 5 nitroaromatic a peptide [BryP acyl- phosphoribosyltransferase histidinol-phosphate SM255186_RS16250 N-acetyl-L- acetyl-α-D-glucosamine phosphatidylserine citrate palmitoleoyl- GMP adenosylcobalamin S-glutatione C59-meroacyl-[acp] [acp] E2 protein] N -lipoyl-L-lysine ribunucleoside- a [release factor]-N dehydratase: dehydrogenase: SM255186_RS21900 S-adenosylmethionine glu glutamate 5- periplasmic precursor: 5'-nucleotidase phosphatidylethanolamine SM255186_RS05975 acyl-carrier protein dehydrogenase in 16S rRNA compound biosynthetic: TrpD: trpD transaminase: glutamate UDP-3-O-acyl-N- adenosine deaminase: pyrophosphoryl-undecaprenol sn-glycerol 2'-phosphate -methyl-L-glutamine carrier protein] cystathionine beta-lyase: semialdehyde decarboxylase proenzyme: SM255186_RS02585 periplasmic precursor: α 2-deoxy-α-D- AMP diphosphate pristanoyl-CoA a cis-delta21-3- ilvA SM255186_RS13845 SM255186_RS13855 SM255186_RS10925 L,L-diaminopimelate synthase: superpathway of L-serine uracil 2-deoxy- - acyl-carrier protein 3-phosphate N-(5-phosphoribosyl) SM255186_RS16250 acetylglucosamine SM255186_RS23430 SM255186_RS08120 ribose 1-phosphate L-homocysteine 2-aminoprop-2-enoate cys O-succinyl-L-homoserine SM255186_RS15840 and glycine biosynthesis I D-ribulose 5-phosphate a (3R)-3- [+ 3 isozymes] SM255186_RS02585 D-ribose 1- oxo-C40:1-[acp] (2Z)-2-aminobut- -anthranilate L-histidinol deacetylase: 3-phenyl-2- 3-(4-hydroxyphenyl) diaminopimelate SAM a (2E)-but- hydroxyoctadecanoyl- 3-oxododecanoyl-CoA [+ 3 isozymes] phosphate phosphopentomutase: 2-enoate phosphate succinylornithine arabinose 5-phosphate SM255186_RS00700 an L-1-phosphatidylethanolamine oxopropanoate pyruvate epimerase: cystathionine 3-phospho-D-glycerate 2-enoyl-[acp] [acp] inosine guanosine 2-aminoprop-2-enoate 5-methyltetrahydropteroyltriglutamate- N-acetylglutamate aminotransferase: UDP-3-O-(3- superpathway of glycolysis and the Entner-Doudoroff pathway phosphopentomutase: deoB L-homocysteine gamma-synthase: phosphoglycerate isomerase GutQ: acetyl-CoA C- UDP-N-acetyl-α-D-muramoyl-L- an L-1- a cis-delta21-39- 745 1-palmitoyl- a 5,6- aspartate aromatic amino bifunctional SM255186_RS17670 methionine synthase: gln hydroxymyristoyl) xanthosine deoB an osmoregulated a nucleoside 1 1,4-dihydroxy- 1-cis-vaccenoyl-sn- pyridoxine a guanine - homocysteine methyltransferase: synthase: SM255186_RS08900 2-deoxy-D-ribose a 2,3,4-saturated phytenate a cis-delta17- N -methyladenine 2-oxoglutarate glutathionylspermidine a RNA-DNA hybrid 20 a holo [BryU acyl- SM255186_RS18585 dehydrogenase: SM255186_RS14410 acyltransferase purine-nucleoside acyl-carrier protein alanyl-γ-D-glutamyl-meso-2,6- a malonyl-[acp] phosphatidyl- a ribonucleic acid GGPP oxo-40-methyl- in 23S rRNA a protein sn-glycerol dihydrouracil a protein 1-(2- aminotransferase: acid transaminase: histidinol- SM255186_RS17575 SM255186_RS21925 SM255186_RS15250 -α-D-glucosamine D-glucopyranose purine-nucleoside 5-phosphate fatty acid C36:1-[acp] periplasmic glucan triphosphate 2-naphthoate glycerol-3-phosphate 5'-phosphate carrier protein] meso-diaminopimelate 5-methyltetrahydropteroyltriglutamate- 2-iminopropanoate SM255186_RS15695 arabinose 5-phosphate FadA: fadA 2-deoxy-D-ribose diaminopimeloyl-D-alanyl-D-alanine acyl-CoA synthetase sn-glycerol DNA oxidative bifunctional ribonuclease HII: C59:1-[acp] 1-acyl-sn-glycerol- 23S rRNA 3-phosphate in tRNA carboxyphenylamino) SM255186_RS04790 SM255186_RS22120 phosphatase/ carbamoyl- N-acetyl-L- UDP-3-O-(3- phosphorylase: phosphorylase: bifunctional 2- serine-type D-Ala-D- beta-ketoacyl- phosphoglycerol DNA-directed 1,4-dihydroxy- multifunctional acyl-CoA 1-acyl-sn-glycerol- tRNA malonyl 2-iminobutanoate - homocysteine methyltransferase: methionine synthase: methionine synthase: isomerase KdsD: a (2E)-octadec- 6-phosphate 5-phosphate FdrA: fdrA demethylase glutathionylspermidine SM255186_RS01170 cyclopropane fatty acyl pyridoxal phosphatase: (guanine(745)-N(1)) -1-deoxy-D-ribulose imidazoleglycerol- L-cystathionine SAH 3-phosphooxypyruvate phosphate synthase: hydroxymyristoyl) acetyl-CoA C- deoD deoD acylglycerophosphoethanolamine Ala carboxypeptidase: ACP synthase I: transferase I: RNA polymerase 2-naphthoate 3-phosphate thioesterase I/protease 3-phosphate dihydrouridine(20/ endopeptidase La: CoA-ACP aromatic amino SM255186_RS17575 SM255186_RS21925 SM255186_RS21925 ornithine long-chain fatty purine-nucleoside deoxyribose- AlkB: alkB phospholipid synthase: phosphate diaminopimelate 2-iminopropanoate a butanoyl-[acp] SM255186_RS17030 2-enoyl-[acp] acyltransferase SM255186_RS03285 long-chain-fatty- SM255186_RS12540 SM255186_RS24420 subunit omega: amidase/synthase: polyprenyltransferase: ribonuclease HI: acyltransferase: SM255186_RS03935 -methyltransferase: I/lysophospholipase L1: acyltransferase: SM255186_RS02350 transacylase: 5-phosphate acid transaminase: tyr 3-phosphoserine/ SM255186_RS00335 glucosamine N- acid activation phosphorylase: deoxyribose- phosphate aldolase: acyltransferase/acyl-ACP an osmoregulated SM255186_RS08315 20a) synthase decarboxylase:methionine synthase: acid--CoA ligase: SM255186_RS16145 SM255186_RS16320 1 SM255186_RS09610 dehydratase 5'-methylthioadenosine/ SM255186_RS00340 superpathway of L-aspartate aldehydo-D-arabinose acyltransferase: FadI: fadI hypoxanthine guanine synthetase: SM255186_RS15350 UDP-N-acetylmuramoyl-L-[+ 2 isozymes] beta-ketoacyl- periplasmic SM255186_RS20165 SM255186_RS18635 SM255186_RS01350 1-cis-vaccenoyl- an N - SM255186_RS02650 a 1-palmitoyl-2-SM255186_RS16320 DusA: dusA a malonyl-fabD SM255186_RS22120 met cystathionine beta-lyase: phosphohydroxythreonine deoD phosphate aldolase: SM255186_RS24550 UTP and CTP dephosphorylation I succinate formaldehyde adenine a nucleoside 5'- a cis-keto-C60- pyridoxine HisB: hisB SM255186_RS12450SM255186_RS21925 beta-ketoacyl- 5-phosphate a long-chain a 2,3,4-saturated SM255186_RS09530 a 1,2-diacyl- spermidine glutathione demethylmenaquinol-4 745 20 pyruvate S-adenosylhomocysteine aminotransferase: and L-asparagine biosynthesis lpxD xanthosine SM255186_RS24550 D-ala alanyl-γ-D-glutamyl-meso-2,6- ACP synthase II: glucan with [+ 2 isozymes] DNA 2-palmitoleoyl-sn- methylguanine a peptide acyl-sn-glycerol a uracil in tRNA a peptide [BryU acyl- diaminopimelate SM255186_RS16250 carbamoyl L-ornithine ACP synthase I: UDP-2-N,3-O-bis[(3R)- fatty acid decanoyl-CoA fatty acyl-[acp] sn-glycerol monophosphate meroacyl-[acp] 2-oxobutanoate phe nucleosidase: mtnN SM255186_RS04685 acyl-CoA phosphorylase: D-glyceraldehyde UTP diaminopimeloyl-D-alanine SM255186_RS05975 phosphoglycerol a ribonucleic acid glycerol-3-phosphate in 23S rRNA 3-phosphate carrier protein] (1S,2R)-1-C-(indol-3- histidinol decarboxylase: met phosphate SM255186_RS12540 3-hydroxytetradecanoyl]- glucose-6-phosphate acetaldehyde diphosphate AMP phytenoyl-CoA a cis-delta19-3- S-ribosyl-L- glu synthetase acyl-CoA xapA D-glyceraldehyde 3-phosphate acyl-carrier protein substituent yl)glycerol 3-phosphate SM255186_RS15385 pyruvate fumarate beta-ketoacyl- α-D-glucosamine a stearoyl-[acp] isomerase: acetaldehyde oxo-C38:1-[acp] acetolactate synthase L-proline biosynthesis histidinol L-homocysteine 2-aminoprop-2-enoate homocysteine O-phospho-L-serine FdrA: fdrA 6-phospho dehydrogenase: 3-phosphate nucleoside CTP synthetase: ACP synthase II: D-arabinofuranose UDP-2,3- SM255186_RS21985 large subunit: tryptophan synthase: I (from L-glutamate) dehydrogenase: S-adenosyl-L-methionine cycle I D-glucono- SM255186_RS01665 triphosphatase: nudI SM255186_RS15000 lys S-ribosylhomocysteine SM255186_RS05975 5-phosphate diacylglucosamine long-chain-fatty- xanthine SM255186_RS19880 SM255186_RS06435 hisD 5-methyltetrahydropteroyltriglutamate- phosphoserine aspartate aspartate 1,5-lactone lyase: 2-dehydro-3- diphosphatase: lpxH acid--CoA ligase: a [2-oxoglutarate- a peptidoglycan dimer (meso 6-O-trans-methoxy- GDP-α-D- uridine 2'3'-cyclic 1-myristoyl- [+ 2 isozymes] trpB - homocysteine methyltransferase: methionine synthase: phosphatase: aminotransferase: ammonia- a 3-oxohexanoyl- 6-phosphogluconolactonase: (2E)-dec-2-enoyl-CoA UDP CTP linoleate a cis-delta13- a (6S)-5- maltoheptaose c-di-GMP a double stranded DNA pyridoxamine 3'-UMP glu SM255186_RS14305 deoxyphosphooctonate SM255186_RS09530 pyrimidine acetyl-CoA dehydrogenase a sulfurated -diaminopimelate containing) a malonyl-[acp] glu mycolyl-trehalose a purine a behenoyl-[acp] mannose a butanoyl-[acp] monophosphate sn-glycerol a protein a protein (S)-2-aceto-2- histidinal L-serine biosynthesis I SAM SM255186_RS21925 SM255186_RS24585 SM255186_RS04790 lyase: aspA [acp] a long-chain purine ribonucleosides degradation SAM C32:1-[acp] formyltetrahydrofolate 5'-phosphate tryptophan SM255186_RS17575 lipid X stearate SM255186_RS03940 nucleoside 6 serine-type D-Ala-D- alpha-glucosidase: 6-phosphate ribonucleoside GDP-mannose bifunctional 2',3'- bifunctional 2',3'- glutamate 5-kinase: 2-iminopropanoate aldolase: acyl-CoA ribonucleosides acetyl-CoA E2 protein] N - [sulfur carrier] long-chain-fatty- beta-ketoacyl- bifunctional cyclic-guanylate-specific DNA/RNA 3-phosphate1-acyl-sn-glycerol- hydroxybutanoate synthase methionine synthase: L-homocysteine phosphoserine triphosphatase: nudI lipoyl Ala carboxypeptidase: SM255186_RS19010 purine-nucleoside beta-ketoacyl- mannosyl hydrolase: beta-ketoacyl- cyclic-nucleotide 2'- cyclic-nucleotide 2'- metalloprotease SM255186_RS01725 histidinol SM255186_RS09300 D-gluconate degradation octanoyl-L-lysine acid--CoA ligase: ACP synthase I: tetrahydrofolate phosphodiesterase: trehalose-phosphatase: nuclease SfsA: sfsA pyridoxal phosphatase: 3-phosphate protease 3: ketol-acid γ-L-glutamyl phosphatase SerB: serB lipid-A-disaccharide long-chain-fatty- synthase: SM255186_RS03285 phosphorylase: ACP synthase I: SM255186_RS11105 ACP synthase I: phosphodiesterase/ PmbA: pmbA subunit dehydrogenase: 3-phospho-D-glycerate SM255186_RS21925 L-citrulline 6-phosphate F6P cytidine urate UMP CDP SM255186_RS09530 SM255186_RS12540 alpha-glucosidase/ SM255186_RS20845 SM255186_RS10100 deoxyribonuclease I: SM255186_RS03935 phosphodiesterase/ S-adenosylmethionine asp synthase: acid--CoA ligase: (S)-3- pyrimidine deoxyribonucleotides a [2-oxoglutarate synthase/dihydrofolate deoD acyltransferase: SM255186_RS15265 reductoisomerase: beta: trpB alanine racemization 5-phosphate hisD phosphoglycerate KDO-8P acyl-CoA hydrolysis cytidine deaminase: adenosine lipA [+ 2 isozymes] alpha-galactosidase: [+ 2 isozymes] SM255186_RS15855 SM255186_RS12540 SM255186_RS12540 3'-nucleotidase: 3'-nucleotidase: [+ 2 isozymes] synthase: ser a (3R)-3- phosphogluconate dephosphorylation an unsulfurated dehydrogenase acyl-CoA synthetase beta-ketoacyl- synthase: α-D-ribose- 1,2-dimyristoyl-SM255186_RS16320 SM255186_RS17875 dehydrogenase: met argininosuccinate SM255186_RS01165 SM255186_RS09530 fructose 1,6- hydroxydecanoyl-CoA bifunctional UDP- 5'-deoxyadenosine met a peptidoglycan with SM255186_RS22395 5'-phosphoguanylyl(3'->5') trehalose-trans- a purine base GDP D-mannose SM255186_RS23715 SM255186_RS23715 gamma-glutamyl- SM255186_RS11565 6 a 5'-phosphooligonucleotide a 3-oxotetracosanoyl- pyridoxamine a 3-oxohexanoyl- SM255186_RS15840 aspartate-- hydroxyhexanoyl- dehydratase: edd 6-phosphofructokinase nucleoside triphosphate sugar hydrolase/ [sulfur carrier] E2 protein] N D-ala D,D cross-links (meso- FdrA: fdrA ACP synthase II: SM255186_RS12475 methoxy-mono-mycolate 1-phosphate sn-glycerol a peptide a peptide (R)-2,3-dihydroxy- ser indole phosphate reductase: his SM255186_RS15695 pyruvate synthase: 3-deoxy-D-manno- lipid A disaccharide acyl-CoA a 2,3,4-saturated bisphosphatase: uridine a (6S)-5- guanosine [acp] [acp] 3'-UMP uridine serine ammonia ligase: [acp] II: SM255186_RS08770 pyrophosphohydrolase: adenosine deaminase: -lipoyl-L-lysine SM255186_RS05975 D-glucopyranose maltohexaose 3-phosphate 3-methylpentanoate ala 3-phosphooxypyruvate SM255186_RS16910 (E. coli) synthetase fatty acyl CoA SM255186_RS23795 xanthosine 5'-nucleotidase CMP diaminopimelate containing) diphosphate linoleoyl-CoA SM255186_RS01730 L-cystathionine SM255186_RS19245 octulosonate multifunctional acyl- KDGP uridine phosphorylase: SM255186_RS15005 SM255186_RS08120 AMP a cis-delta15-3- formyltetrahydrofolate alanine racemase met SAH hydroxymethyltransferase: tetraacyldisaccharide FdrA: fdrA periplasmic precursor: acyl-carrier protein tryptophan L-arginino- 8-phosphate CoA thioesterase β-D-fructose 1,6- SM255186_RS17560 dCTP dCMP oxo-C34:1-[acp] biosynthetic: L-glutamate-5- 3-phosphoserine/ SM255186_RS13530 asparagine synthase 4'-kinase: DHAP 3-oxodecanoyl-CoA SM255186_RS02585 bifunctional UDP- synthase L-glutamate cystathionine succinate phosphatase KdsC: I/protease I/ SM255186_RS22115 semialdehyde phosphohydroxythreonine serine B: SM255186_RS03460 stearoyl-CoA bisphosphate uracil sugar hydrolase/ subunit superpathway of L-alanine biosynthesis gamma-synthase: SM255186_RS17035 SM255186_RS04725 2-dehydro-3-deoxy- purine-nucleoside adenosine inosine guanosine [+ 3 isozymes] biosynthesis III aminotransferase: 5-methyltetrahydropteroyltriglutamate- 5'-methylthioadenosine/ hydroxymethyltransferase: argininosuccinate lyase: a (2E)-hex- lysophospholipase L1: class II fructose- acetyl-CoA C- deoxyuridine 5'-nucleotidase (S)-3-methyl-2- [+ 3 isozymes] phosphorylase: 6-O-cis-methoxy- 4-methylphenyl-Co an [apo BCAA 1-cis-vaccenoyl- 1-palmitoyl- beta: trpB - homocysteine methyltransferase: S-adenosylhomocysteine SM255186_RS18585 asn 2-enoyl-[acp] lipid IV (E. coli) SM255186_RS02650 phosphogluconate bisphosphate aldolase: triose-phosphate acyltransferase 5'-triphosphate uridine periplasmic precursor: a [pyruvate (5Z,8Z,11Z,14Z,17Z) a double 1-carboxyvinyl an N-terminal- α oxopentanoate L-cysteine biosynthesis I SM255186_RS04685 SM255186_RS18560 SM255186_RS18485 α-Kdo A 1-cis-vaccenoyl-sn- a cis-delta15- maltopentaose long chain -ribazole D-ala 2-oxoglutarate 3-methyl-2- superpathway of L-asparagine biosynthesis a 2,3,4-saturated aldolase: deoD dehydrogenase a sulfurated decanoate a malonyl-[acp] coenzyme A a sugar phosphate mycolyl-trehalose β-adenosylcobamide L-methionyl-L- dehydrogenase E2 protein] sn-glycerol- sn-glycerol SM255186_RS17575 nucleosidase: mtnN SM255186_RS15745 isomerase: FadA: fadA nucleotidohydrolase: SM255186_RS02585 a palmitoleoyl-[acp] -icosapentaenoate stranded DNA carboxyphosphonate 5'-phosphate L-ornithine repressor LexA branched chain amino oxobutanoate cys fatty acid SAM 6 glycerol-3-phosphate C34:1-[acp] alpha-glucosidase: polyphosphate 6 trp NADP-specific L-asparaginase 1: 3-deoxy-D-manno- SM255186_RS20030 SM255186_RS18685 xanthosine purine-nucleoside purine-nucleoside purine-nucleoside E2 protein] N - [sulfur carrier] long-chain-fatty- acyl-CoA synthetase exodeoxyribonuclease sugar phosphatase: carboxyvinyl- 6-phosphate 5'-phosphate seryl-[protein] N -dihydrolipoyl-L-lysine 3-phosphate 3-phosphate (S)-1-pyrroline- O-phospho-L-serine methionine synthase: gly arg 3-deoxy-manno- acetyl-CoA C- SM255186_RS20215 [+ 3 isozymes] 1-acyl-sn-glycerol- beta-ketoacyl- adenosylcobalamin/ methionine 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- adenosylcobalamin/ acid aminotransferase: glutamate branched chain amino SM255186_RS08945 adenosine nucleotides phosphorylase: phosphorylase: phosphorylase: phosphorylase: octanoyl-L-lysinelipoyl acid--CoA ligase: FdrA: fdrA SM255186_RS19010 dihydrolipoyl spermidine N1- LexA 5-carboxylate ser octulosonate octulosonic acid 3-phosphate ACP synthase I: V: SM255186_RS15255 SM255186_RS12305 carboxyphosphonate trehalose-phosphatase: alpha-ribazole aminopeptidase: 3-phosphate 3-phosphate alpha-ribazole SM255186_RS17905 SM255186_RS21925 L-homocysteine S-ribosyl-L-homocysteine acid aminotransferase: asp cyclopropane fatty acid acyltransferase degradation III nucleoside triphosphate synthase: exopolyphosphatase: ppx dehydrogenase: acetyltransferase: repressor: serine dehydrogenase: L-asparaginase 2: transferase: D-glyceraldehyde xapA deoD deoD deoD cytidine acyltransferase: SM255186_RS09530 SM255186_RS12540 long-chain-fatty- alpha-glucosidase/ SM255186_RS15260 sugar/pyridoxal phosphate phosphorylmutase: SM255186_RS10100 map acyltransferase: acyltransferase: phosphatase: pyrroline-5- phosphoserine cytidylyltransferase: (CFA) biosynthesis FadI: fadI pyrophosphohydrolase: S-methyl-5'-thioadenosine lipA a [pyruvate phosphatase: lpdA speG lexA acetyltransferase: SM255186_RS08920 cys SM255186_RS17905 SM255186_RS15920 SM255186_RS20250 3-phosphate acid--CoA ligase: alpha-galactosidase: SM255186_RS15270 SM255186_RS01895 an N-terminal carboxylate reductase: phosphatase: a hexanoyl-[acp] SM255186_RS04740 SM255186_RS15005 degradation IV an unsulfurated dehydrogenase SM255186_RS163201-cis-vaccenoyl- acyl-CoA synthetase beta-ketoacyl- phosphatase YigL: yigL trehalose- SM255186_RS03315 met an [apo BCAA 1,2-dicis-SM255186_RS16320 1-palmitoyl-SM255186_RS16320 SM255186_RS03315 ile glycine a [phospholipid] α-D-ribose- 5'-deoxyadenosine met SM255186_RS22395 long chain N 5 -acetyl- cleaved SM255186_RS20380 glu α dUTP 6 FdrA: fdrA SM255186_RS09530 a 5'-phosphooligonucleotide a sugar carboxyphosphinopyruvate cis-methoxy- 4-methylphenyl-Co L-seryl-[protein] α-ribazole SM255186_RS01990 SM255186_RS24585 asparagine synthase aspartate--ammonia ligase: -Kdo-(2->6)- octanoyl-CoA AMP dUMP S-methyl-5'- [sulfur carrier] E2 protein] N acyl-carrier protein 2-palmitoleoyl-sn- ACP synthase II: polyphosphate dehydrogenase E2 vaccenoyl- 2-myristoyl biosynthesis IV O-acetyl-L-serine val asp CMP-Kdo olefinic fatty acid 1-phosphate (5Z,8Z,11Z,14Z,17Z) β-adenosylcobamide 6 L-ornithine repressor LexA L-glutamine B: SM255186_RS03460 SM255186_RS19245 beta-ketoacyl- lipid IV (E. coli) cyclopropane fatty acyl -lipoyl-L-lysine SM255186_RS05975 D-glucopyranose maltotetraose mono-mycolate protein] N -lipoyl-L-lysine phosphatidate phosphatidate phosphoserine cysteine desulfurase: A thioadenosine glycerol-3-phosphate S-ribosylhomocysteine ACP synthase I: acyl-CoA AMP nucleosidase: 5'-methylthioadenosine/ diphosphate AMP decanoyl-CoA -icosapentaenoyl-CoA biosynthesis I pro phosphatase SerB: serB SM255186_RS08585 pyruvate asparagine synthase phospholipid synthase: phosphopentomutase: a cis-delta17-3- cysteine lyase: SM255186_RS14305 SM255186_RS12540 dehydrogenase: SM255186_RS10580 acyl-carrier protein thr glycine biosynthesis II B: SM255186_RS03460 a [phospholipid]SM255186_RS08315 13-DPG 5-hydroxy-CTP 5-hydroxy-CMP deoB S-adenosylhomocysteine oxo-C36:1-[acp] low-specificity L- synthase A: cysK cysteine valine--pyruvate asn SM255186_RS01665 nucleosidase: mtnN glu ser beta-ketoacyl- cyclopropane adenine D-ribose 5- threonine aldolase: cysteine synthase desulfurase alanine transaminase: transaminase: MTR glutamate-- a [glycine-cleavage complex ACP synthase II: fatty acid phosphoglycerate phosphate CysM: cysM CsdA: csdA SM255186_RS12720 SM255186_RS20560 (2E)-oct-2-enoyl-CoA α-L-fucosyl-(1->3)- 1-palmitoyl- SM255186_RS04480 gly 6 asn SM255186_RS05975 kinase: undecaprenyl-diphospho-N 1-(oleoyl)-sn-glycero-3- 5'-deoxy-5'- a [protein]- ammonia ligase: H protein] N -lipoyl-L-lysine a 2,3,4-saturated a 2,3,4-saturated 2- a 1,4-α-D-glucan a cis-delta11- a ribonucleoside a protein with carboxyphosphinopyruvate glutathione RX a [protein] Ser/Thr palmitoyl-CoA β a nucleoside gly glycine cleavage -acetylmuramoyl-L-alanyl-γ- UDP-N-acetyl-α-D-glucosamine a malonyl-[acp] phosphoethanolamine formate glutathione fluoroadenosine β-alanine -D-glucopyranosyl- sn-glycerol ser L-histidine SM255186_RS19070 a 3-oxooctanoyl- SM255186_RS15750 fatty acyl-[acp] lysophosphatidate C30:1-[acp] triphosphate a disulfide bond 4'-phosphopantetheine ATP diphosphate cys system protein H: gcvH D-glutamyl-L-lysyl- D-alanine glycogen multifunctional acyl- carboxyvinyl- glutathione S- stress response purine-nucleoside diphosphoundecaprenol 3-phosphate sensor gln a [glycine-cleavage complex H protein] ala 3-phospho- undecaprenyldiphospho- 1-acyl-sn-glycerol- beta-ketoacyl- anaerobic glutaredoxin 3: acyl-CoA 4-aminobutyrate- colanic acid 1-acyl-sn-glycerol- L-serine [acp] phosphorylase: phosphopantetheine transferase: kinase A: phosphorylase: nucleoside- 6 α-Kdo-(2->4)-α-Kdo- muramoylpentapeptide beta-N- 3-phosphate ACP synthase I: CoA thioesterase ribonucleoside- SM255186_RS20365 carboxyphosphonate dehydrogenase: biosynthesis 3-phosphate histidine N -aminomethyldihydrolipoyl-L-lysine D-glycerate SM255186_RS21245 -2-oxoglutarate diphosphate kinase: ammonia-lyase: (2->6)-lipid IV (E. coli) (S)-3- Polymeric Compound acetylglucosaminyltransferase: SM255186_RS12540 I/protease I/ triphosphate reductase: [+ 2 isozymes] adenylyltransferase: phosphorylmutase: SM255186_RS20465 SM255186_RS19140 deoD SM255186_RS01665 acetyltransferase acyltransferase: kinase A Carboxylate Degradation acyltransferase: a protein with transaminase: SM255186_RS13380 SM255186_RS09570 2,3-bisphosphoglycerate- hydroxyoctanoyl-CoA Degradation maltodextrin lysophospholipase L1: SM255186_RS20245 SM255186_RS01895 [+ 3 isozymes] [+ 2 isozymes] 5-fluoro-5- DpiB: dpiB ditrans,octacis-undecaprenyldiphospho-murG SM255186_RS16320a 2,3,4-saturated beta-ketoacyl- SM255186_RS23885 reduced L- GSSG 3'-dephospho- (2E)- SM255186_RS14155 acetyl-L-fucosyl-(1->3)WcaF: wcaF 1-palmitoyl-2-SM255186_RS16320 a [protein]- 2+ 2+ independent phosphorylase: a 2'-deoxyribonucleoside 3-(hydroxyphosphinoyl) a glutathione- a [protein] (L-serine/L- deoxy-D-ribose adenine a nucleoside [+ 4 isozymes] Mg RS23915 Mg UDP N-acetyl-(N-acetylglucosaminyl)muramoyl- ACP synthase II: SM255186_RS02650 cysteine residues CoA HX hexadecenoyl-CoA 3-oxopropanoate -β-D-glucopyranosyl- cis-vaccenoyl N-phospho- a (3R)-3- phosphoglycerate L-ascorbate degradation muropeptide degradation acyl-carrier protein 1,2-diacyl-sn- sn-glycero-3- pyruvate S-conjugate 1-phosphate triphosphate pyruvate L-ascorbate degradation D-glucosaminate degradation D-threonate degradation γ SM255186_RS21275 oleate 5'-triphosphate threonine) phosphate hydroxyoctanoyl- α-Kdo-(2->4)-α- mutase: II (bacterial, aerobic) glycolate and L-alanyl- -D-glutamyl-L-lysyl-D-alanine glycerol 3-phosphate α SM255186_RS05975 diphosphoundecaprenol phosphatidate L-histidine γ -D-glucopyranose phosphoethanolamine [acp] Kdo-(2->6)-(lauroyl) I (bacterial, anaerobic) glyoxylate degradation I L-alanyl- -D- a 1,4-α-D-glucan acyl-carrier protein a cis-delta13-3- SM255186_RS20355 3-oxooctanoyl-CoA 2-amino-2-deoxy- 1-phosphate -lipid IV (E. coli) glutamyl-meso-2,6- oxo-C32:1-[acp] 2+ 2+ A L-ascorbate L-ascorbate D-threonate Mg RS20050 Mg superpathway of (Kdo) -lipid A biosynthesis Cell Structure Biosynthesis lauroyl-Kdo(2) 2-phospho- glycolate D-gluconate diaminopimeloyl- 2 acetyl-CoA C- 6-phosphate D-threonate kinase: peptidoglycan biosynthesis I (meso-diaminopimelate containing) enterobacterial common antigen biosynthesis peptidoglycan maturation (meso-diaminopimelate containing) D-glycerate L-ascorbate-6- D-alaninemuramoyltetrapeptide -lipid IV(A) acyltransferase SM255186_RS00850 a (3R)-3- phosphate lactonase: 4-phospho- carboxypeptidase: decaprenyl-diphospho-N- UDP-N-acetyl- a linear malto- all-trans- (E)-1-(L-cystein-S- a 1-alkyl-sn 1498 α a (2E)-oct- myristoyltransferase: enolase: L-dehydro- 2-amino-2-deoxy-D- L-alanyl-γ-D- a cis-delta9- a 1-acyl-sn-glycero- 1,4-dihydroxy- a 5-L-glutamyl- ADP-D-ribose 5'-chloro-5'- a uracil a [protein]- - 3'-cmp a cytidine 34 UDP-N-acetyl-α-D-glucosamine α-D-glucopyranose lipid II (meso FadA: fadA SM255186_RS23595 SM255186_RS09440 α 2-methylbutanoate oligosaccharide a malonyl-[acp] undecaprenyl stearoyl-CoA H O glutathione fenclorim enterobactin palmitoleoyl-CoA -glycerol 3- lys UDP-N-acetyl- hydroxytetradecanoyl- D-threonate acetylmuramoyl-pentapeptide -D-glucosamine 3-phosphocholine an amino acid yl)-N-hydroxy-2-(4- 2 deoxyadenosine in 16S rRNA L-glutamate Ile2 2-enoyl-[acp] msbB palmitoleate SM255186_RS14995 ascorbate 3-keto-L-gulonate glyoxylate gluconate 6-phosphate glutamyl-meso- C28:1-[acp] 2-naphthoate [peptide] in tRNA α 1-phosphate diaminopimelate containing) α acetyl-CoA C- undecaprenyldiphospho- acetyl-coenzyme glycogen multifunctional acyl- diphosphate hydroxyphenyl)ethan-1-imine multifunctional acyl-CoA glutathione S- ADP-ribose purine-nucleoside phosphate 16S rRNA bifunctional 2',3'- -D-glucosamine [acp] UDP-N-acetylglucosamine -D-Kdo-(2->4) biosynthesis I (from diaminopimelate beta-ketoacyl- 1,4-dihydroxy- gamma- cystathionine acyl-CoA 1-acyl-sn-glycerol- protein-glutamate O- tRNA(Ile) peptidoglycan phosphoenol acyltransferase 6-phosphate D-glucosaminate- muramoylpentapeptide beta-N- A synthetase: phosphorylase: CoA thioesterase thioesterase I/protease diphosphatase: enterochelin esterase: phosphorylase: (uracil(1498)-N(3))- cyclic-nucleotide 2'- 1-carboxyvinyltransferase: glucose-1-phosphate -α-D-Kdo-(2->6) (5Z)-dodec-5-enoate) glyoxylate ACP synthase I: 2-naphthoate glutamyltransferase: beta-lyase: transferase: dehydrogenase: 3-phosphate methyltransferase -lysidine glycosyltransferase pyruvate FadI: fadI 6-phosphate murein acetylglucosaminyltransferase: SM255186_RS21245 SM255186_RS16380 SM255186_RS03010 phosphodiesterase/ murA thymidylyltransferase -lipid A (E. coli) 3-keto-L- carboligase: SM255186_RS22270 SM255186_RS12540 I/protease I/ polyprenyltransferase: SM255186_RS21160α SM255186_RS16250 I/lysophospholipase L1: SM255186_RS20465 SM255186_RS01665 deoD acyltransferase: methyltransferase: CheR: cheR synthetase: a (5Z)-dodec- ammonia lyase: 3-dehydro-4- tripeptide an -(5-L- (Z)-N-hydroxy-2- 5-chloro-5- FtsI: ftsI pyruvate kinase I: dehydroascorbate murG maltodextrin lysophospholipase L1: SM255186_RS02650 [+ 3 isozymes] N-(2,3- 3 SM255186_RS15860 a [protein]-L- 3'-nucleotidase: UDP-N-acetyl-α-D- RfbA: rfbA gulonate-6- gcl phospho-L- decaprenyl-pyrophosphoryl- 2-methylbutanoyl- beta-ketoacyl- SM255186_RS18635 a peptide glutamyl)- pyruvate (4-hydroxyphenyl) D-ribofuranose (2E,9Z)- a 2-acyl-1-alkyl-SM255186_RS16320 an N - tilS 5-enoyl-[acp] phosphoenolpyruvate hexanoyl-CoA SM255186_RS20025 amidase AMP diphosphate 4-(glutathion- AMP adenine deoxyribose 5 SM255186_RS23715 34 UDP-3-O-[(3R)-3- [+ 2 isozymes] beta-ketoacyl- SM255186_RS08560 (bicyclic form) phosphorylase: SM255186_RS02650 stearate dihydroxybenzoyl) 1498 glutamate-O a lysidine D-ribulose glucosamine-enolpyruvate polymyxin resistance UDP-N-acetyl- glucose-1-phosphate an octanoyl-[acp] synthase: phosphate tartronate erythronate UDP (N-acetylglucosamine)-N- CoA ACP synthase II: DMKH2-11 amino acid acetimidothioate 5-phosphate hexadecenoyl-CoA sn-glycerol methyluracil MpaA: SM255186_RS21275 sn-glycero-3- S-yl)-fenclorim 1-phosphate Ile2 5-phosphate hydroxymyristoyl]- α a nascent peptidoglycan ACP synthase II: pyruvate acyl-CoA decarboxylase SM255186_RS05975 a carboxylate -L-serine 3-phosphate in 16S rRNA -methyl-ester cytidine in tRNA UDP-N- -D-glucosamine thymidylyltransferase: SM255186_RS08645 semialdehyde KDGP mpaA acetylmuramyl-(pentapeptide) α phosphocholine N-acetyl-α-D- UDP-α-D- with (L-alanyl-γ-D-glutamyl- beta-ketoacyl- heptosyl-Kdo -lipid A SM255186_RS05975 kinase: pyk dehydrogenase: UlaD: ulaD -D-glucopyranose a linear malto- a cis-delta11-3- arabinose 5-phosphate UDP-N- rfbA 2 2-hydroxy-3- acyl-carrier protein glucosamine acetylenolpyruvoylglucosamine glu glucuronate meso-2,6-diaminopimeloyl-D- ACP synthase I: beta-ketoacyl- SM255186_RS01665 L-alanyl-D- 1-phosphate oligosaccharide oxo-C30:1-[acp] isomerase GutQ: acetylglucosamine α ADP-heptose--LPS 3-keto-L-gulonate- 2-dehydro-3-deoxy- UDP-3-O-acyl-N- reductase: SM255186_RS18410 dTDP- -D-glucose alanyl-D-alanine) pentapeptide SM255186_RS12540 ACP synthase I: pyruvate 2,3-dioxo- oxopropionate glutamate SM255186_RS14410 ala 2-epimerase (non- 6-phosphate phosphogluconate DHAP acetylglucosamine α aspartate/glutamate heptosyltransferase trans-hex-2-enoyl-CoA L-gulonate reductase: L-Ala-D/L-Glu UDP-N-acetyl- -D-muramate di-trans,octa-cis- dTDP-glucose 4,6- beta-ketoacyl- a (7Z)-3-SM255186_RS12540 decarboxylase UlaD: aldolase: arabinose 5-phosphate racemase: hydrolyzing): UDP-N-acetyl- RfaF: rfaF 2,3-diketo-L- SM255186_RS16705 deacetylase: undecaprenyl phosphate serine-type D-Ala-D- serine-type D-Ala-D- ACP synthase II: oxotetradec- SM255186_RS20030 epimerase: an L-1- α-D-Kdo-(2->4)-α-D- 2,5-dichloro-trans D-cellobiose 4-amino-4- all-trans- a 1-acyl-2- an N-terminal- a [protein]- isomerase KdsD: SM255186_RS15395 UDP-β-L-threo- SM255186_RS17810 α-D-glucosamine dehydratase: rfbB (heptosyl) - SM255186_RS23615 maltohexaose 1,4-dihydroxy- a proteinogenic oleoyl-CoA H O an adenine in DNA D-alanyl-D-alanine selenide SM255186_RS00700 UDP-N-acetylmuramate- Ala carboxypeptidase: Ala carboxypeptidase: 2 7-enoyl-[acp] gulonate reductase: 2-hydroxy-3- SM255186_RS06750 Kdo-(2->6)-lipid A (E. coli) 6'-phosphate deoxy-α-L- dodecaprenyl glutathione L-djenkolate arachidonoyl- 2 a purine 2'- L-methionyl-L- a decanoyl-[acp] SM255186_RS17030 pentapyranos- UDP-N-acetyl-α- undecaprenyl- dTDP-glucose SM255186_RS05975 L-xylulose D-glyceraldehyde phosphatidylethanolamine -dienelactone α-Kdo-(2->4)- 2-naphthoate amino acid CTP ATP H O L-tyrosine ATP UDP-3-O-(3- glutamate racemase: SM255186_RS03285 SM255186_RS03285 a mature peptidoglycan with Kdo -lipid A SM255186_RS20545 oxopropionate 6-phospho-beta- alpha-glucosidase: deoxyribonucleoside DNA adenine 2 selenide, -L-alanine ligase: 2 pyruvate L-alanyl-L- kdo(2)-lipid A arabinopyranosyl diphosphate gamma- cystathionine sn-glycerol multifunctional acyl-CoA alanyl-[protein]methionine D-alanyl-D-alanine tyrosine-protein aldehydo-D- hydroxymyristoyl) 4-ulose D-mannosamine phosphate alpha-N- 4,6-dehydratase: γ a 3-oxodecanoyl- 5-phosphate 3-phosphate carboxymethylenebutenolidase: α-Kdo-(2->6)- SM255186_RS19010 1,4-dihydroxy- purine-nucleoside beta-ketoacyl- ATPase SM255186_RS00675 SM255186_RS18440 [+ 2 isozymes] [+ 2 isozymes] (L-alanyl- -D-glutamyl-meso- (S)-3- reductase: glutamate phosphoethanolamine glucosidase: ditrans,octacis 3-phosphatephosphatidate thioesterase I/protease methylase: dipeptidase: water arabinose 5- α UDP-4-amino-4- acetylglucosaminyl 1- SM255186_RS17800 3-keto-L-gulonate lipid IV (E. coli) 2-naphthoate glutamyltransferase: beta-lyase: phosphorylase: aminopeptidase: kinase wzc: - -D-glucosamine UDP-N-acetyl-D- [acp] L-ribulose-5-phosphate SM255186_RS02715 SM255186_RS17565 A ACP synthase I: RavA: ravA adenylate cyclase: 2,6-diaminopimeloyl-D-alanyl- hydroxyhexanoyl-CoA 7''-transferase: SM255186_RS08830 -undecaprenyl alpha-glucosidase/ SM255186_RS21160 SM255186_RS16250 cytidylyltransferase: I/lysophospholipase L1: SM255186_RS21430 SM255186_RS07170 SM255186_RS11150 dikinase phosphate UDP-3-O-(3- α deoxy-L-arabinose phosphate transferase: dTDP-4-dehydro-6- a (3R,7Z)-3- cytosol nonspecific 4-amino-4-deoxy- polyprenyltransferase: an α-(γ-L- α deoD map SM255186_RS12540 [+ 5 isozymes] UDP-N-acetyl- -D- D-glt mannosamine a nascent peptidoglycan a nascent peptidoglycan D-alanine) pentapeptide glucosyl-(heptosyl) 3-epimerase: SM255186_RS20705 6-phospho-beta- phosphate alpha-galactosidase: S-(sulfanylmethyl) a CDP-1-acyl-SM255186_RS01130 SM255186_RS02650 2-deoxy- - [+ 2 isozymes] an N-terminal L- a [protein]- SM255186_RS17715 SelD: selD aminotransferase: dipeptidase: L-arabinose lipid SM255186_RS18635 6 a 3- hydroxymyristoyl) dehydrogenase: SM255186_RS17820 deoxy-α-D-glucopyranose γ hydroxytetradec- SM255186_RS20505 (R)-glycerate 7-O-[2-aminoethoxy(hydroxy) L-cysteinylglycine glutamyl)-L- pyruvate an N -methyladenine met + muramoyl-L-alanine with (L-alanyl- -D-glutamyl- with D,D cross-links (meso- -Kdo -lipid A 2,5-dichloromaleylacetate glucosidase: SM255186_RS22395 -L-cysteine 2-arachidonoyl- oleate D-ribose 1- a purine base alanyl-[protein] D-ala H phosphate ADP L-tyrosine SM255186_RS12115 α 2 2 7-enoyl-[acp] SM255186_RS01700 phosphoryl]-α-D-Kdo-(2->4) a 1,2-diacyl-sn-glycerol A4'- transferase:α-L-Ara4N DMK-12 amino acid oxododecanoyl- cyclic-AMP selenophosphate glucosamine N- SM255186_RS17805 N-acetyl- -D- dTDP-4-amino-4,6- meso-2,6-diaminopimeloyl- diaminopimelate containing) L-ribulose-5-phosphate glycerol phosphate in DNA phosphate UDP-4-amino- lipopolysaccharide glycerate -α-D-Kdo-(2->6)-lipid A SM255186_RS15630 di-trans,octa-cis SM255186_RS12135-α-Kdo-(2-> D-glucopyranose maltopentaose [acp] acyltransferase: UDP-N-acetylmuramoyl- UDP-N-acetyl-α-D- glucosaminyldiphospho- dideoxygalactose D-alanine) tetrapeptide a (3R)-3- 3-epimerase UlaE: D-glucopyranose D-arabinofuranose 4-deoxy-β-L- core heptose(I) 3-keto-L-gulonate 2-kinase: superpathway of acetate utilization and formation ala glu -undecaprenyl lpxD L-alanine--D- mannosaminuronate ditrans,octacis-undecaprenol transaminase: hydroxydecanoyl- 3-oxohexanoyl-CoA pyruvate fermentation D-glucopyranose 4)-α-KDO-(2- 5-phosphate arabinopyranose kinase RfaP: rfaP 6-phosphate SM255186_RS23620 garK 6-phosphate phosphate UDP-2-N,3-O-bis[(3R)- glutamate ligase: SM255186_RS17785 L,D-transpeptidase: muramoyltetrapeptide L,D-transpeptidase: [acp] to acetate IV >6)-lipid IV a mature peptidoglycan a (2E,7Z)- acetyl-CoA C- L-ribulose 5- A 2-dehydro-3- 3-hydroxytetradecanoyl]- bifunctional UDP- lipopolysaccharide N- glucosyl-(heptosyl) - 3-keto-L- 2-phospho- acetate SM255186_RS00660 SM255186_RS04220 carboxypeptidase: SM255186_RS04220 2 tetradeca-2,7- acyltransferase deoxyphosphooctonate glucuronic acid dTDP-4-amino-4,6- with D,D cross-links (meso- phosphate acetyl-coenzyme α-D-glucosamine acetylmannosaminouronosyltransferase: Kdo -lipid A-phosphate gulonate-6- D-glycerate pyruvate ω [+ 2 isozymes] SM255186_RS09440 [+ 2 isozymes] a mature peptidoglycan 2 dienoyl-[acp] FadA: fadA a peptide with N-acetyl-muramoyl-(L- an all-trans- 1407 an N-terminal- 2498 an N -(1- aldolase: meso-diaminopimelate α oxidase/UDP-4- dideoxy-α-D-galactose diaminopimelate containing) L-ribulose-5- acetate/propionate A synthetase: an L-1- α-Kdo-(2->4)-α-Kdo- 5-chloro-trans 1-carboxyvinyl a cytosine a myo-inositol a cytidine UDP-2,3- UDP-N-acetyl- -D-muramoyl- SM255186_RS17765 with (L-alanyl-γ-D-glutamyl- lipopolysaccharide phosphate octanoate γ 1,4-dihydroxy- 2,3- lauroyl-CoA H O NADH DHAP citrate amino-4-deoxy- fatty acid elongation -- saturated acetyl-CoA C- family kinase: SM255186_RS22270 phosphatidylethanolamine (2->6)-lipid IV (E. coli) -dienelactone an N-terminal alanyl- -D-glutamyl-L- polyisoprenyl ser a pimeloyl-[acp] ala 2 carboxyphosphonate in 16S rRNA L-methionyl-L- in 23S rRNA hydroxy-2- D-serine SM255186_RS09300 diacylglucosamine L-alanyl-D-glutamate D-ala dTDP-4-amino-4,6- a nascent peptidoglycan a nascent peptidoglycan with a nascent peptidoglycan a (2E)-dec- decarboxylase phosphate 4- A 2-naphthoate dihydroxybenzoate monophosphate meso-2,6-diaminopimeloyl- core kdo(2)-lipid A Xaa-L-proline long-chain-fatty- lysyl-D-alanyl-D-alanine) diphosphate multifunctional acyl-CoA carboxyvinyl- NADH 16S rRNA valyl-[protein]methionine 23S rRNA glycerol-3-phosphate citrate (pro-3S) oxopropyl) L-arabinose N-acetyl-β-D- dideoxy-D-galactose γ with (L-alanyl-γ-D-glutamyl- acyltransferase UlaD: ulaD epimerase: formate C- SM255186_RS10825 cytosol aminopeptidase: serine-type D-Ala-D- 1,4-dihydroxy- enterobactin synthase 8-amino-7- bifunctional glucose- D-serine diphosphatase: lpxH with L,D cross links (meso- (L-alanyl- -D-glutamyl-meso- D-alanine) tetrapeptide 2-enoyl-[acp] heptosyltransferase carboxymethylenebutenolidase: acid--CoA ligase: thioesterase I/protease carboxyphosphonate pyrophosphatase: (cytosine(1407)-C(5) (cytidine(2498)-2'-O) dehydrogenase -lyase: citF citE KDO-8P formyltransferase: FadI: fadI acetyltransferase: phosphoethanolamine SM255186_RS24030 Ala carboxypeptidase: 2-naphthoate component D: oxononanoate aminopeptidase: 1-phosphatase/ -[protein]- ammonia- UDP-N-acetylmuramoyl- D-alanine--D- mannosaminuronyl- acyltransferase: diaminopimelate containing) 2,6-diaminopimelate) tripeptide meso-2,6-diaminopimeloyl- a (7Z)-tetradec- 3-keto-L-gulonate- araD [+ 2 isozymes] SM255186_RS17565 RfaQ: rfaQ an acetoacetyl-[acp] pflB 7''-transferase: SM255186_RS09530 SM255186_RS03285 synthase: bioF I/lysophospholipase L1: phosphorylmutase: SM255186_RS18275 )-methyltransferase map inositol phosphatase: -methyltransferase (NAD(P)(+)): citrate (pro-3S) L-arginineprotein lipid X L-alanyl-D-glutamate-- alanine ligase B: arnA (1->4)-N-acetyl-α-D- SM255186_RS17790 glycine) tetrapeptide [+ 2 isozymes] acetyl phosphate acetyl-CoA Xaa-Pro polyprenyltransferase: SM255186_RS03000 β lyase: glucosyl-(heptosyl) - 7-enoyl-[acp] butanoyl-CoA 6-phosphate SM255186_RS20705 acyl-CoA synthetase 8-amino-7- SM255186_RS02650 SM255186_RS01895 reduced - RsmF: rsmF an N-terminal RlmM: rlmM SM255186_RS20375 -lyase: citE citF deglycase 3-deoxy-D-manno- UDP-4-deoxy-4- 3 7-O-[2-aminoethoxy(hydroxy) aminopeptidase: [+ 2 isozymes] SM255186_RS18635 enterobactin 1407 met SM255186_RS05525 a 2-O- dsdA 2, 6-diaminopimelate SM255186_RS00680 glucosaminyl-diphospho- dTDP-4-acetamido-4,6- decarboxylase UlaD: D-xylulose formate C- 5-chloromaleylacetate N-acetyl-muramoyl-(L- acyl-carrier protein 3-(hydroxyphosphinoyl) nicotinamide D- AMP a 5-methylcytosine lipid-A-disaccharide β Kdo -lipid A-phosphate oxononanoate L-valyl-[protein] 2498 sn-glycerol aYajL: [protein]- yajL octulosonate ligase: formamido- -L- α 2 beta-ketoacyl- acetyltransferase: phosphoryl]-α-D-Kdo-(2->4) a 1,2-diacyl-sn-glycerol SM255186_RS15670 FdrA: fdrA γ DMKH laurate myo-inositol methylcytidine oxaloacetate acetate (R)-lactate pyruvate ditrans,octacis-undecaprenol dideoxy- -D-galactose acyl-CoA 5-phosphate a peptide with D-ala alanyl- -D-glutamyl- 2 in 16S rRNA synthase: D-alanine--D- a mature peptidoglycan a mature peptidoglycan with lipopolysaccharide ACP synthase I: SM255186_RS23615 a proteinogenic pyruvate ribonucleotide 3-phosphate L-arginine 8-phosphate SM255186_RS00645 arabinopyranose a decanoyl-[acp] dehydrogenase: pflB -α-D-Kdo-(2->6)-lipid IV an N-terminal L-lysyl-D-alanine) in 23S rRNA SM255186_RS01165 alanine ligase A: undecaprenyl- with L,D cross-links (meso- (L-alanyl-γ-D-glutamyl-meso- a mature peptidoglycan core heptose(II) SM255186_RS12540 L-xylulose A amino acid diphosphate AMP octanoyl-CoA phosphatase KdsC: TDP-N-acetylfucosamine:lipid II SM255186_RS01665 citrate degradation L-proline lipid A α SM255186_RS01960 phosphate 4-deoxy- lipid IV biosynthesis (P. putida) diaminopimelate containing) 2,6-diaminopimelate) tripeptide with (L-alanyl-γ-D-glutamyl- kinase RfaY: rfaY 5-phosphate SM255186_RS17035 UDP-N-acetyl- -D-muramoyl- N-acetylfucosaminyltransferase: A beta-ketoacyl- beta-ketoacyl- a 3-oxoacyl-[acp] phosphate disaccharide γ meso-2,6-diaminopimeloyl- acetyl-CoA formate L-alanyl- -D-glutamyl- D-alanyl-D-alanine 4-formamido-L- SM255186_RS17775 ACP synthase I: glucosyl-(heptosyl) ACP synthase II: crotonyl-CoA L-ribulose-5-phosphate acetyltransferase: α-Kdo (E. coli) arabinose transferase: glycine) tetrapeptide -Kdo -lipid A- an acetyl-holo [citrate meso-2,6-diaminopimelate a (3R)-3- UDP-N-acetyl- SM255186_RS12540 3 2 SM255186_RS05975 3-epimerase: citrate SM255186_RS12330 lyase acyl-carrier protein] phosphate 2-amino-6-[1-hydroxyethyl]- 2-chloro-cis- α di-trans,octa-cis 1-palmitoyl- an [amino group carrier protein]-C- (4S)-4-hydroxy-2- 6-O-cis-keto- a cytosine 1962 adenosyl-cob(III) uridine 746 a cytidine 1402 tetraacyldisaccharide SM255186_RS12120 (enterobacterial hydroxydecanoyl-[acp] α-D-glucosamine bisphosphate a (9Z)-3- beta-ketoacyl- SM255186_RS20505 citrate (pro-3S) UDP- -D- maltohexaose a cis- S-fenclorimyl- O-succinyl-L- formate a uridine in tRNA 3-deoxy-manno- Nucleoside and Nucleotide Biosynthesis beta-ketoacyl- acetyltransferase: phosphate -undecaprenyl sn-glycerol γ mycolyl-trehalose PLP phosphoenol 4'-kinase: UDP-N-acetylmuramoyl- 4-deoxy-4- common antigen)- lipopolysaccharide 1,6- oxohexadec- -lyase: citE citF 7-methyl-7,8-dihydropterin dienelactone galactose vaccenoyl-[acp] terminal- -(L-ornithyl)-L-glutamate L-cysteine homoserine oxoheptanedioate in 23S rRNA yrinate a,c-diamide in 23S rRNA in 16S rRNA GTP H O dADP UDP-3-O-[(3R)-3- ACP synthase II: ACP synthase II: L-ribulose-5-phosphate SM255186_RS12330 acetyltransferase: pta 2-amino-4-hydroxy-6- phosphate maltodextrin 4-hydroxy-2-oxo- 6-phosphate 23S rRNA 23S rRNA 16S rRNA 2 formate tRNA pyruvate octulosonate SM255186_RS04725 α galactosyltransferase: undecaprenyl- 1-acyl-sn-glycerol-3-phosphate succinylornithine cystathionine cystathionine pyridoxal phosphatase: cobyric acid tripeptide--D-alanyl- formamido- -L- undecaprenyl diphosphate 9-enoyl-[acp] SM255186_RS05975 3-epimerase UlaE: citrate (pro-3S) carboxymethylenebutenolidase: phosphorylase: GTPase cytidylyltransferase: hydroxydecanoyl]-N- SM255186_RS05975 (S)-3- phosphate hydroxymethyldihydropteridine heptane-1,7- trehalose-phosphatase: SM255186_RS03935 (cytosine(1962)-C(5) pseudouridine (cytosine(1402)-N(4) dehydrogenase- dihydrouridine pyruvate D- alanine ligase: arabinopyranosyl superpathway of purine nucleotides de novo biosynthesis II SM255186_RS20280 phosphate galactose 3-phosphate aminotransferase: beta-lyase: gamma-synthase: synthase CobQ: HflX: hflX SM255186_RS04740 lipid IV (E. coli) acetyl-α-D-glucosamine superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) adenine and a 3- beta-ketoacyl- hydroxybutanoyl-CoA SM255186_RS23620 -lyase: citF citE diphosphokinase: SM255186_RS17565 SM255186_RS21275 dioate aldolase: )-methyltransferase synthase F: )-methyltransferase: N subunit synthase kinase: pyk A CMP phosphorylation a citryl-holo [citrate acetyltransferase: pta phosphotransferase acyltransferase: SM255186_RS08900 SM255186_RS16250 SM255186_RS18585 SM255186_RS10100 sugar/pyridoxal phosphate SM255186_RS10635 SM255186_RS00650 ditrans,octacis UDP-3-O-acyl-N- oxododecanoyl- lipopolysaccharide a (3R)-3- L-ribulose 5- [+ 4 isozymes] adenosine salvage I a 2,3,4-saturatedACP synthase I: lyase acyl-carrier protein] SM255186_RS00970 glycogen an [amino group carrier protein]- 6-chloro-2-phenyl- SM255186_RS05460 RlmI: rlmI SM255186_RS21950 4 rsmH alpha: fdnG DusB: dusB -undecaprenyl [1-(2-amino-7-methyl-4-oxo- WbaP: SM255186_RS16320 pyruvate succinate L-homocysteine phosphatase YigL: yigL 1962 746 an N - CMP-Kdo (enterobacterial acetylglucosamine PRPP CTP [acp] 3-alpha- a (3R,9Z)-3- hydroxyacyl-[acyl- phosphate D-gluconate degradation 2-chloromaleylacetate 1-palmitoyl-2- γ succinate trehalose-cis-keto- a 5-methylcytosine adenosylcobyrate a pseudouridine + an electron- a 5,6-dihydrouridine dATP pyruvate α CMP fatty acyl-[acp]SM255186_RS12540 acetyl phosphate phosphorylase: C-terminal- -(L-glutamate 5- 4-sulfanylpyrimidine pyruvate 1402 phosphate GDP H CO UDP-N-acetyl- -D-muramoyl-L- 7,8-dihydro-3H-pteridin- SM255186_RS10975 pyridoxal methylcytidine 2 phosphate deacetylase: galactosyltransferase: hydroxyhexadec- carrier protein] citrate (pro-3S) α acyl-carrier protein cis-vaccenoyl semialdehyde mono-mycolate in 23S rRNA in 23S rRNA transfer quinol in tRNA alanyl-γ-D-glutamyl-meso-2,6- di-trans,octa-cis- common antigen)- cytidylate kinase: L-ribulose-5- -D-galactosyl- SM255186_RS21245 semialdehyde-2-yl)-L-glutamate 3-deoxy-D-manno- amidophosphoribosyltransferase: nucleoside SM255186_RS20285 6-yl)]ethyl diphosphate UMP α phosphatidate in 16S rRNA undecaprenyl phosphate undecaprenyl diphosphate SM255186_RS00700 adenosine SM255186_RS04700 9-enoyl-[acp] acetoacetyl-CoA phosphate 4- -lyase: citE citF acetate/propionate D-gluconate diphosphoundecaprenol -D-glucopyranose octulosonic acid diaminopimeloyl-D-alanyl-D-alanine UDP-3-O-(3- SM255186_RS12460 triphosphatase: nudI galactosyl-glucosyl- maltopentaose purine-nucleoside CDP epimerase: citrate (pro-3S) family kinase: gluconokinase: 1-phosphate transferase: hydroxydecanoyl) a (3R)-3- (heptosyl) -Kdo - 4-amino-4- CDP phosphorylase: 3 2 acetyl-CoA C- -lyase: citF citE SM255186_RS10825 α β gly nucleoside- hydroxydodecanoyl- araD SM255186_RS21205 SM255186_RS20250 α - -D-glucosamine 5-phospho- -D-ribosylamine deoD lipid A-bisphosphate acyltransferase D-gluconate deoxy- -L- diphosphate kinase: [acp] a (2E,9Z)- [+ 2 isozymes] [+ 2 isozymes] α α UDP-3-O-(3- ribonucleoside- ribonucleoside- adenine oxaloacetate 2,5-diamino-6-(5- 2-chloro-trans a peptidoglycan a plant soluble S-(4-hydroxy- 3-heptaprenyl-4- GDP- -D- -Kdo-(2->6)- arabinopyranosyl FadI: fadI 6-phosphate a peptide with a glutathione O-succinyl-L- 6-O-trans-keto-mycolyl- a nucleoside + undecaprenyldiphospho- diphosphate reductase diphosphate reductase: SM255186_RS13380 hexadeca-2,9- D-xylulose phospho-D-ribitylamino) dimer (E. faeciums) heteroglycan monochlorobimane 2-methylpentan- methanethiol roseoflavin cis-vaccenoyl-CoA NAD NADPH a hexanoyl-[acp] mannose pyrazinamide ala phosphoenol lipid IV (E. coli) hydroxymyristoyl) a trans-2- acetate -dienelactone trehalose 6-phosphate ATP triphosphate hydroxybenzoate dGDP A N-acetylmuramoyl-L-alanyl- ditrans,octacis α-D-Kdo-(2->4) phosphoribosylamine- dienoyl-[acp] a 2,3,4-saturated [+ 2 isozymes] serine-type D-Ala-D- glycogen penultimate glycine homoserine GDP-mannose glucosamine N- subunit alpha: SM255186_RS12010 adenine CTP enoyl-[acyl- 5-phosphate pyrimidin-4(3H)-one bifunctional glutathione S- 2-yl)-L-cysteine cystathionine 5'-phosphate 4-hydroxy-3- acyl-CoA soluble pyridine bifunctional pyruvate γ -undecaprenyl α -glycine ligase: purD galactosyl-(glucosyl) fatty acyl-[acp] carboxymethylenebutenolidase: carboxypeptidase/ cystathionine nucleoside triphosphate beta-ketoacyl- -D-glutamyl-meso-2,6- - -D-Kdo-(2->6) acyltransferase: SM255186_RS12010 SM255186_RS12015 acetyl-CoA Ala carboxypeptidase: phosphorylase: transferase: trehalose-phosphatase: bifunctional riboflavin polyprenylbenzoate nucleotide pyrophosphatase nicotinamidase/ pyruvate phosphate phosphoribosyltransferase: -(heptosyl) -Kdo - carrier protein] diaminohydroxyphosphoribosylaminopyrimidine penicillin-binding beta-lyase: gamma-synthase: pyrophosphohydrolase: dehydrogenase: alanine transaminase: diaminopimeloyl-D-alanyl-D-alanine -lipid A (E. coli) a (2E)-dodec- 2 3 2 SM255186_RS17565 SM255186_RS03285 SM255186_RS21245 kinase/FAD synthetase: decarboxylase: transhydrogenase: ACP synthase I: NudK: nudK lpxD UDP SM255186_RS02530 lipid A-bisphosphate deaminase/5-amino-6-(5-phosphoribosylamino) protein 1A: SM255186_RS20465 SM255186_RS16250 SM255186_RS18585 SM255186_RS10100 SM255186_RS01665 pyrazinamidase: SM255186_RS12720 kinase: pyk α-Kdo-(2->4)- dCDP formate 2-enoyl-[acp] [+ 2 isozymes] 4-methyl-4- SM255186_RS15005 SM255186_RS18470 SM255186_RS12540 undecaprenyldiphospho- UDP-2-N-[(3R)-3- GAR UTP Inorganic Nutrient Metabolism uracil reductase RibD: ribD maltodextrin SM255186_RS21380 [+ 3 isozymes] pyruvate roseoflavin adenineSM255186_RS00230 SM255186_RS17510 (2E,11Z)- α-D-mannose SM255186_RS08950 α 4-amino-4-deoxy- 2-chloromaleylacetate a peptidoglycan tetramer (glutathion- succinate met trehalose-trans- a nucleoside 5'- GMP pyrazine-2- dGTP pyruvate -Kdo-(2->6)- muramoylpentapeptide beta-N- hydroxydodecanoyl]-3-O- ribonucleoside- ribonucleoside- a palmitoleoyl-[acp] 5-amino-6-(5-phospho- phosphorylase: a peptide with a sulfanylpentan-2-ol 2-heptaprenylphenol NADP + NADH a 3-oxooctanoyl- pyruvate anaerobic AMP D-ala with a D,D cross-link an amino acid keto-mono-mycolate dinucleotide octadecenoyl-CoA 1-phosphate lipid IV (E. coli) acetylglucosaminyltransferase: L-arabinose lipid [(3R)-3-hydroxydecanoyl]- phosphoribosylglycinamide nucleoside- diphosphate reductase diphosphate reductase: D-ribitylamino)uracil SM255186_RS21275 S-yl)-bimane monophosphate [acp] carboxylate A ribonucleoside- anaerobic (aminomethyl)phosphonate degradation C-terminal glycine A transferase: α formyltransferase 2: diphosphate kinase: galactosyl-(glucosyl) urea cycle (Enterococcus faecium) α-D-glucopyranose a plant soluble murG -D-glucosamine triphosphate reductase: ribonucleoside- subunit alpha: SM255186_RS12010 superpathway of sulfate assimilation and cysteine biosynthesis LpxL/LpxP lipid II (meso SM255186_RS12135 UDP-2,3- SM255186_RS09865 SM255186_RS13380 SM255186_RS12010 SM255186_RS12015 -(heptosyl) -Kdo - 1-phosphate heteroglycan SM255186_RS23885 triphosphate reductase: 3 3 2 (aminomethyl) family Kdo(2)- a dodecanoyl-[acp] lipid A-bisphosphate diaminopimelate containing) 4'-α-L-Ara4N-α- diacylglucosamine FGAR SM255186_RS23885 phosphonate 3-phospho-D-glycerate α-Kdo-(2->4) lipid IV(A) lauroyl/ dCTP dUDP aminoalkylphosphonate arg α diphosphatase: lpxH palmitoleate sulfate dissimilatory sulfate α Kdo-(2->4)- - 1-stearoyl- 2,3,6- [(R)-1- an intrastrand non- a dimer of non- (3-aminopropyl) an insertion sequence 3-nonaprenyl-4- (7Z)- a guanine 1207 1-oleoyl-sn - -Kdo-(2->6) palmitoleoyl N-acetyltransferase: phosphoglycerate reduction I (to a peptidoglycan an apo [peptidyl- glutathione N,N'-diacetylchitobiose histidinol Kdo-(2->6)-[P4'- lipid X (P. putida) phosphoribosylformylglycinamidine nucleoside- an oleoyl-[acp] sn-glycerol coenzyme A trichlorohydroquinone adjacent cyclobutane hν adjacent 2'- D-threo-isocitrate -glycerol 3- L-tartrate D-cysteine -(lauroyl)-lipid acyltransferase: deoxycytidine beta-ketoacyl- SM255186_RS22335 sulfate hydrogen sufide)) dGTP carrier protein] aminoethyl]phosphonate hν phosphonate element IS30 hydroxybenzoate tetradecenoyl-CoA in 16S rRNA α-L-ara4N]-lipid A synthase: SM255186_RS13580 guanine and core oligosaccharide- (acetamidomethyl) dehydrogenase: lysozyme: glutathione S- thymidine dimer in DNA chitin disaccharide 4-hydroxy-3- NADP-dependent 16S rRNA phosphate L(+)-tartrate IV (E. coli) lpxL triphosphate deaminase: diphosphate kinase: ACP synthase I: adenylyltransferase: argininosuccinate lyase: ammonium 1-acyl-sn-glycerol-3-phosphate holo-ACP synthase: aminoalkylphosphonate deoxyribodipyrimidine deoxycytidines aminoalkylphosphonate transposase: acyl-CoA 1-acyl-sn-glycerol- histidinol A guanosine salvage II lipid A (E. coli K-12 phosphonate SM255186_RS15695 deoxyguanosinetriphosphate SM255186_RS20875 deacetylase: D-cysteine lipid-A-disaccharide SM255186_RS11175 SM255186_RS13380 SM255186_RS12540 sulfate SM255186_RS18485 SM255186_RS13640 transferase: N-acetyltransferase: in DNA deoxyribodipyrimidine N-acetyltransferase: SM255186_RS19525 polyprenylbenzoate dehydrogenase: isocitrate (guanine(1207)-N(2) dehydratase: dehydrogenase: lauroyl-Kdo(2) kdo(2)-lipid IV(A) FGAM core type) (no GlcNAc) cysN triphosphohydrolase: 3-phosphate photo-lyase: SM255186_RS08825 3-phosphate desulfhydrase: synthase: laurate sulfate carbamoyl- [+ 2 isozymes] SM255186_RS20465 SM255186_RS22335 β photo-lyase: SM255186_RS22335 decarboxylase: SM255186_RS01665 dehydrogenase: )-methyltransferase SM255186_RS17225 hisD -lipid IV(A) palmitoleoyltransferase: beta-ketoacyl- lipopolysaccharide N- SM255186_RS14895 3-phosphooxypyruvate SM255186_RS01060 a N-acetylmuramoyl- acyltransferase: 4'-phosphopantetheinyl SM255186_RS03615 N-acetyl- -D- [+ 7 isozymes] acyltransferase: SM255186_RS10215 SM255186_RS01165 biotin-carboxyl carrier adenylyltransferase: phosphate synthase: N-acetyl-D- [+ 3 isozymes] a DNA with SM255186_RS03615 an insertion SM255186_RS17510 SM255186_RS06180 2 RsmC: rsmC SM255186_RS17230 myristoyltransferase: dUTP guanosine ACP synthase II: acetylglucosaminyltransferase: pentapeptide- SM255186_RS163201-stearoyl-2- transferase: 2,6-dichloro-3- [(1R)-1- acetate glucosaminyl-(1->4) a 2'-deoxycytidine (2-acetamidopropyl) (2E,7Z)- an N - SM255186_RS16320 SM255186_RS12700 phosphoribosylformylglycinamidine long-chain-fatty- cysN L-arginino-succinate L-ornithine 2'-deoxyguanosine triphosphate glucosamine nonadjacent thymidines sequence IS30 with dioleoyl his SM255186_RS05975 protein assembly α-D-ribose 1- APS 3-phosphoserine/ SM255186_RS00335 (glutathion-S-yl) acetamidoethyl]phosphonate phosphonate 2-nonaprenylphenol tetradecenoyl-CoA 2-oxoglutarate methylguanine 1207 oxaloacetate pyruvate msbB lipid A disaccharide (P. putida) cyclo-ligase: SM255186_RS13245 deoxyuridine acid--CoA ligase: SM255186_RS20305 selenate reduction diphosphoundecaprenol acyl-carrier protein oleoyl-sn-glycerol SM255186_RS21005 -D-glucosamine in DNA α superpathway of guanosine superpathway of adenine and (acetamidomethylphosphonate) phosphohydroxythreonine SM255186_RS14895 SM255186_RS00340 a holo [peptidyl- integrated transposon phosphatidate -D-Kdo-(2->4) Kdo - SM255186_RS09530 core oligosaccharide- a [biotin 3-phosphate 3',5'-ADP -hydroquinone in 16S rRNA 2 5'-triphosphate UDP adenylyl-sulfate APS -α-D-Kdo-(2->6) tetraacyldisaccharide AIR nucleotides de novo biosynthesis I adenosine nucleotides adenosine salvage III carboxyl-carrier 5-triphosphate aminotransferase: carrier protein] (palmitoleoyl) nucleotidohydrolase: a 3-oxotetradecanoyl- acyl-CoA lipid A (E. coli kinase: cysC -lipid A (E. coli) 4'-kinase: de novo biosynthesis I guanine protein]-L-lysine SM255186_RS04685 selenate carbamoyl phosphate -lipid IV SM255186_RS20215 [acp] synthetase K-12 core type) A SM255186_RS04725 5-(carboxyamino) sulfate lauroyl-Kdo(2) bifunctional IMP adenine FdrA: fdrA PAPS argininosuccinate synthase: N-acetyl-D-glucosaminyl-N- a dimer of adjacent S-(6-hydroxy- 37 38- a [protein]- imidazole ribonucleotide nucleoside triphosphate IMP asp hypoxanthine α-D-ribose-1-(2-N- O-phospho-L-serine adenylyltransferase: (6Z,9Z,12Z,15Z,18Z,21Z)-3- 1-stearoyl- 1-myristoyl- a Chi-site containing [(S)-1- 3-decaprenyl-4- propane-1,2,3- adenine a uridine -lipid IV(A) lipid IV (P. putida) biotin-- an acyl-[acyl- N-methyl-L- a dipeptide π long chain A purine-nucleoside SM255186_RS16910 acetylmuramoyl-L-alanyl-D-glutamyl- thymidine and 2'- hν 4-methylhexan- (S)-5-hydroxyisourate a cytosine in DNA val N -phospho- synthase: pyrophosphohydrolase: phosphoribosyltransferase: acetamidomethylphosphonate) cysN oxotetracosahexaenoyl-CoA sn-glycerol a myristoyl-[acp] sn-glycerol double stranded RecA aminoethyl]phosphonate a peptide hydroxybenzoate tricarboxylate in tRNA 40 in tRNA myristoyltransferase: adenylosuccinate phosphorylase: lauroyl-CoA [acetyl-CoA- phosphoadenosine sulfite L-citrulline carrier protein] tryptophan 1 polyphosphate SM255186_RS02780 IMP SM255186_RS15005 SM255186_RS00890 phosphoserine SM255186_RS14895 acetyl-CoA C- 6-carboxy-L-lysyl-D-alanine 3-phosphate 3-phosphate DNA with a blunt end deoxycytidine in DNA 4-yl)-L-cysteine 4-hydroxy-3- FAD-dependent tRNA(1)(Val) cytosol nonspecific tRNA L-histidine synthetase: purA a (3R)-3- carboxylase] 5-phosphate phosphosulfate adenosine 5'- muramoyltetrapeptide 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- exodeoxyribonuclease aminoalkylphosphonate deoxyribodipyrimidine cystathionine Xaa-Pro N-methyl-L- 5-hydroxyisourate DNA cytosine msbB dehydrogenase: deoD phosphatase: acyltransferase FadA: fadA polyprenylbenzoate tricarballylate (adenine(37)-N(6))- pseudouridine(38- phosphohistidine polyphosphate dUMP adenylo-succinate xanthine ligase/biotin anaerobic sulfite carboxypeptidase: 3-phosphate 3-phosphate V: SM255186_RS15255 N-acetyltransferase: photo-lyase: beta-lyase: aminopeptidase: tryptophan oxidase: hydrolase: methyltransferase: dipeptidase: (Kdo) -lipid N5-CAIR guaB adenosine hydroxytetradecanoyl- reductase: phosphoselenate phosphatase 2 SM255186_RS24585 acetyl-CoA C- decarboxylase: dehydrogenase TcuA: methyltransferase: SM255186_RS01700 40) synthase kinase: ppk1 phosphoribosyltransferase: [acp] operon SM255186_RS22800 reductase: asrA asrB N-acetyl-D-glucosaminyl-SM255186_RS09440N- acyltransferase: acyltransferase: SM255186_RS15260 SM255186_RS22335 SM255186_RS03615 SM255186_RS16250 SM255186_RS15670 SM255186_RS05770 SM255186_RS05410 SM255186_RS10400 A, cold adapted thymidylate synthase: adenylosuccinate lyase: phosphatidylglycerol adjacent thymidine-2'- 3-methyl-3- a proteinogenic (S)-2-oxo-4- SM255186_RS17510 SM255186_RS03520 SM255186_RS13715 TruA: truA SixA: sixA SM255186_RS01705 phosphoserine SM255186_RS13505 acyltransferase FadI: fadI SM255186_RS16320 SM255186_RS16320 a double strandedSM255186_RS15270 DNA [(1S)-1- pyruvate a 5-methylcytosine an N 6 - 5-(carboxyamino) SM255186_RS15305 biosynthesis II (non-plastidic) repressor [+ 2 isozymes] (4Z,7Z,10Z,13Z,16Z,19Z) D-ala acetylmuramoyl-L-alanyl-D- a 1-stearoyl 2- 1,2-dimyristoyl- a peptide trp formaldehyde a proteinogenic a pseudouridine 38- a [protein]- long chain XMP SM255186_RS06150 α deoxycytidine in DNA sulfanylhexan-1-ol amino acid hydroxy-4-carboxy- 2-decaprenylphenol cis-aconitate 37 imidazole ribonucleotide adenosine deaminase: BirA: birA 5-phospho- -D-ribose phosphatase SerB: serB acetyl-CoA glutamyl-6-carboxy-L-lysine acyl-carrier protein acyl-sn-glycerol acyl-carrier protein sn-glycerol with a RecA protein acetamidoethyl]phosphonate in DNA methyladenine amino acid L-histidine phosphatidylglycerol a [DsrC]-trisulfide -docosahexaenoyl-CoA 5-ureidoimidazoline 40 in tRNA polyphosphate mutase: purE dTMP SM255186_RS08120 GMP a [biotin carboxyl- 1,2-cyclic phosphate sulfite 3-phosphate 3-phosphate loaded 3' overhang in tRNA val biosynthesis I (plastidic) DHAP ser selenite 1 GMP synthase: thymidylate kinase: AMP a (2E)-tetradec- glycerol-3-phosphate carrier protein]-N gluconeogenesis I Carbohydrate Biosynthesis CAIR 6 assimilatory β SM255186_RS12915 SM255186_RS05990 2-enoyl-[acp] dehydrogenase -biotinyl-L-lysine O-antigen building blocks biosynthesis (E. coli) ADP-L-glycero- -D-manno PRPP biosynthesis inosine DHAP sulfite reductase 2-phospho-4-(cytidine 5'- a mature a dimer of adjacent S-(4-hydroxy- a holo-[EntF (3Z)-hex- a double-stranded 1516 747 a [protein]- serine acetyltransferase: a 10- an L-methionyl- a 4-hydroxy-3- a guanine a uracil τ xanthine and (NAD(P)(+)): succinate an alkylated DNA ν L-threo-3- glutathione a [histone]-L-lysine Ins(6)P N -phospho- 3-methylgentisate -heptose biosynthesis dTDP glycerol-3-phosphate α 2-aminoethylphosphonate Met diphospho)-2-C-methyl-D-erythritol peptidoglycan 2'-deoxycytidine and h 3-methylbutan- ser L-seryl-carrier α phosphoribosylaminoimidazolesuccinocarboxamide adenylate kinase: -D-ribose 1,5- (NADPH): cysI SM255186_RS20380 ammonium hydrogencarbonate ATP (n) 3-en-1-ol polyprenylbenzoate oligonucleotide in 16S rRNA in 23S rRNA (S)-malate UDP- -D- α-D- D-glucopyranose xanthosine salvage SM255186_RS20375 formyltetrahydrofolate [initiator tRNA ] phenylserine L-histidine D-ribose 5- synthase: SM255186_RS13175 GMP SM255186_RS02555 purine-nucleoside dehydrogenase bisphosphate SM255186_RS14965 hydrogen sulfide degradation I methionyl-tRNA 2-C-methyl-D-erythritol (meso-DAP succinyl-CoA DNA-3-methyladenine thymidine in DNA 2-yl)-L-cysteinecystathionine protein]enterobactin synthase low-specificity L- glutathione S- 4-hydroxy-3- 16S rRNA 23S rRNA galactose D-sedoheptulose nucleoside- sn-glycerol selenodiglutathione deoxyribodipyrimidine protein lysine oligoribonuclease: bifunctional glucose- gentisate 1,2- glucopyranose 6-phosphate phosphate phosphorylase: (NAD(P)(+)): a [biotin carboxyl- carbamate kinase: arcC 2,4-cyclodiphosphate containing) lytic transglycosylase: ligase subunit beta: glycosylase 2: transferase: polyprenylbenzoate (guanine(1516)-N(2) (uracil(747)-C(5))- phosphohistidine glucose-6-phosphate 7-phosphate ribose-phosphate 3-phosphate O-acetyl-L-serine formyltransferase: photo-lyase: beta-lyase: component D: threonine aldolase: acetyltransferase: 1-phosphatase/ dioxygenase: 1-phosphate phosphoheptose diphosphate kinase: carrier-protein hydrogen sulfide (2-aminoethyl)phosphonate carbamate kinase: synthase: SM255186_RS22635 SM255186_RS03760 SM255186_RS11190 SM255186_RS20465 SM255186_RS23440 methyltransferase phosphatase glucose-1-phosphate isomerase: SAICAR deoD xanthosine SM255186_RS20375 an N-formyl- SM255186_RS21825 a DNA containing SM255186_RS03615 SM255186_RS16250 SM255186_RS03000 SM255186_RS04480 decarboxylase: SM255186_RS13760 )-methyltransferase inositol phosphatase: gtdA pyrophosphokinase: guanylate kinase: SM255186_RS13380 ADP a myristoyl-[acp] sn-glycerol glycerol-3-phosphate 6 GlcNAc-1,6- a mature a seryl-[EntF SixA: sixA UDP-Galf thymidylyltransferase isomerase: dimer]-N - 2-aminoethylphosphonate-- SM255186_RS02775 SM255186_RS14865 [+ 4 isozymes] an alkylated adjacent 2'-deoxycytidine- 2-methyl-3- [+ 3 isozymes] SM255186_RS17510 6 2 RsmJ: rsmJ RlmC: rlmC (2E)-2-methyl- SM255186_RS21985 SM255186_RS09340 L-methionyl- a tetrahydrofolate anhMurNAc- peptidoglycan an apurinic/ pyruvate L-seryl-carrier gly benzaldehyde a [histone]-N - a nucleoside 5'- an N - SM255186_RS05525 747 a [protein]- SM255186_RS01670 adenylosuccinate lyase: SM255186_RS20170 purine-nucleoside 3-phosphate 1-O-acyltransferase: biotinyl-L-lysine pyruvate aminotransferase: carbamoyl phosphate 2-C-methyl-D-erythritol- (n) phosphate ADP succinyl-CoA nucleobase thymidine in DNA sulfanylbutan-1-ol 3-(glutathion-S a 2-(all-trans- a 5-methyluracil RfbA: rfbA F6P D-glycero-D- dTTP hypoxanthine met 1516 myo-inositol 4,6-dioxohept- PRPP beta-ketoacyl- cysteine [initiator tRNA ] CMP L-Ala-γ-D-Glu- (meso-DAP apyrimidinic site protein] -yl)-hexan-1-ol polyprenyl)phenol acetyl-L-lysine monophosphate methylguanine in 23S rRNA L-histidine oxaloacetate pyruvate SM255186_RS06150 ribonucleoside- phosphorylase: deoD glycerol-3-phosphate SM255186_RS22055 acetyl-CoA PRPP thiosulfate SM255186_RS02230 2,4-cyclodiphosphate 2-enedioate glucose-1-phosphate manno-heptose ACP synthase I: synthase A: cysK glutathioselenol DAP-D-Ala containing) in 16S rRNA colanic acid building blocks biosynthesis glutamine--fructose- 7-phosphate diphosphate reductase: hypoxanthine xanthosine 1-O-acyltransferase: glycerol-3- carboxylase disproportionation phosphonoacetaldehyde thymidylyltransferase: GDP SM255186_RS12540 adenine cysteine synthase 6-phosphate bifunctional heptose AICAR SM255186_RS12010 phosphoribosyltransferase: phosphorylase: xapA SM255186_RS22055 phosphate carboxyl IV (rhodanese) A(H2) thiosulfate phosphoenolpyruvate phosphoenolpyruvate rfbA xanthine beta-ketoacyl- phosphoribosyltransferase: CysM: cysM phosphonoacetaldehyde dTDP-α-D-glucose aminotransferase: SM255186_RS12015 6-O-α-mycolyl- 2030 an S-(1-hydroxy- tetrathionate D-glucopyranose 7-phosphate kinase/ SM255186_RS00890 glycerol-3- acyltransferase: transferase SM255186_RS02530 core a ring-opened 7- 1-palmitoyl- (2-aminoethyl) (R)-propane- adenine carboxykinase synthase: bifunctional ACP synthase II: acetyl-CoA thiosulfate hydrolase: isobutanoate 3'-dephospho- propanoate L-talarate Ins(2)P 4-methylgentisate reductase 6-phosphate SM255186_RS19335 heptose 1-phosphate xanthine phosphate plsY subunit an L-1- oligosaccharide- methylguanine in DNA a palmitoyl-[acp] sn-glycerol O-acetyl-L-serine hydrogen selenide felinine L-cystathionine phosphonate 1,2-diol trehalose 6- L-dopa in 23S rRNA asp 2-oxopropyl) (ATP): pckA SM255186_RS08645 dTDP- CDP-paratose biosynthesis phosphoribosylaminoimidazolecarboxamide nucleoside- ribonucleoside- xanthine SM255186_RS05975 carboxylase thiosulfate SM255186_RS02235 ATP A tetrathionate D-glucosamine adenyltransferase: dADP phosphoribosyltransferase: a 1-acyl-sn alpha: accA hydrogen selenide phosphatidylethanolamine lipid A (E. coli formamidopyrimidine- acetyl-coenzyme 3-phosphate CoA propionate-- aminoalkylphosphonate lactaldehyde phosphate L-talarate/galactarate 23S rRNA bifunctional glucose- -[protein]- gentisate 1,2- glucose 4,6- formyltransferase/IMP cyclohydrolase: purH phosphoribosyltransferase: acyltransferase: biotin diphosphate cys sulfurtransferase: 1-acyl-sn-glycerol- cysteine synthase cystathionine cystathionine diphosphate kinase: diphosphate reductase: -glycerol 3- K-12 core type) DNA glycosylase: A synthetase: dephospho-CoA kinase: CoA ligase: prpE reductase: fucO 4,5-DOPA (adenine(2030)-N(6) aspartate L-cysteine alpha-D-glucose glucose-6-phosphate dehydratase: 6-phosphate SM255186_RS16455 CDP-4-dehydro-3,6- SM255186_RS01705 SM255186_RS01705 a 3-oxohexadecanoyl- plsY acetyl-CoA acetaldehyde phosphoethanolamine 3-phosphate beta-lyase: beta-lyase: N-acetyltransferase: trehalose-phosphatase: dehydratase: 1-phosphatase/ protein dioxygenase: phosphoenol D-glycero-β-D- SM255186_RS13380 SM255186_RS12010 nucleoside- carboxylase hydrogen sulfide SM255186_RS21255 SM255186_RS20240 SM255186_RS22270 CysM: cysM dioxygenase extradiol: aminotransferase: phosphate-specific isomerase: phosphoglucosamine dideoxy-α-D-glucose FAICAR [acp] a 1-acyl-sn phosphate inorganic transferase EptA: eptA 2,6-diamino-4- acyltransferase: SM255186_RS00740 SM255186_RS16250 SM255186_RS16250 SM255186_RS22335 lactaldehyde reductase: SM255186_RS10100 SM255186_RS20390 )-methyltransferase inositol phosphatase: deglycase gtdA pyruvate rfbB CDP-paratose SM255186_RS12015 diphosphate kinase: carboxylase subunit: accC thiosulfate an apurinic site SM255186_RS16400 SM255186_RS04790 phosphoglucomutase: SM255186_RS21985 manno-heptose 1-acyl-sn-glycerol- pyrophosphatase: biosynthesis I AMP diphosphate propanoyl-CoA acetate L-selenocysteine 3-methyl-3- SM255186_RS15155 6 RlmJ: rlmJ YajL: yajL (2E)-3-methyl- mutase: IMP XMP -glycerol 3- carboxyl lipid A-core- [+ 2 isozymes] hydroxy-5-(N-methyl) SM255186_RS16320 + pyruvate pyruvate L-homocysteine (2-acetamidoethyl) α α 5-dehydro-4- an N - SM255186_RS05525 a [protein]- dTDP-glucose 1,7-bisphosphate synthase: bifunctional SM255186_RS13380 3-phosphate sulfurtransferase phosphate acquisition a 1,2-diacyl- within DNA isobutanoyl-CoA AMP diphosphate ADP coenzyme A H sulfanylbutan-1-ol , '-trehalose (R)-lactate enolase: SM255186_RS03555 SM255186_RS23790 dipalmitoyl (R)-lactaldehyde 4,5-seco-dopa 2030 oxaloacetate 4,6-dioxohept- 4,6-dehydratase: SM255186_RS16925 phosphate transferase pyrophosphoethanolamine sn-glycerol formamidopyrimidine acyl-carrier protein phosphonate 6-α-mycolate deoxy-D-glucarate methyladenine myo-inositol L-cysteine SM255186_RS14995 D-glycero-beta-D- SM255186_RS11015 phosphoribosylaminoimidazolecarboxamide GTP 1-acyl-sn-glycerol- acyltransferase: PspE: pspE phosphatidate 2-enedioate F6P α-D-glucosamine α subunit cys in 23S rRNA α-D- SM255186_RS17800 manno-heptose CDP- -D-paratose formyltransferase/IMP cyclohydrolase: purH dGDP dATP a (3R)-3- SM255186_RS16320 phosphate sulfite thiocyanate acetyl-CoA a phosphate 2-phospho- pyrimidine 3-phosphate beta: accD 1-phosphate 1,7-bisphosphate a 1,2-diacyl- monoester glucopyranose mannose-6- dTDP-4-dehydro- ribonucleosides salvage I hydroxyhexadecanoyl- acyltransferase: a [carboxyl-carrier acid phosphatase AphA: D-glycerate α bifunctional UDP-N- sn-glycerol 1-phosphate 6-deoxy- -D- 7-phosphatase: nucleoside- [acp] 6 a dimer of non-adjacent 1-palmitoyl- (E)-1-(L-cystein-S-yl)-N- S-(5- S-(4-oxo-2- a peptidyl- 7,8- glycyl-L- phosphate isomerase: IMP SM255186_RS16320 protein dimer]-N 3-mercaptopyruvate SM255186_RS22125 phosphatidylglycerolphosphate a sulfurated orotidine 5'- sn-glycerol an oligopeptide an aromatic a nucleoside 2,3-bisphosphoglycerate- glucopyranose acetylglucosamine SM255186_RS01275 cytidine a 1,2-diacyl- 3-phosphate 2'-deoxycytidine and hν isovalerate sn-glycerol a myristoyl-[acp] hydrogen cyanide hydroxy-ω-(methylsulfanyl) hydroxypentan- methylpentan- dipeptidase diaminopelargonate methionine an acyl phosphate Ins(1)P spermidine UTP--glucose- SM255186_RS08100 diphosphate kinase: -carboxybiotinyl- non-specific acid (1-oleoyl, 2-palmitoyl) [sulfur carrier] phosphate 3-phosphate amino acid triphosphate independent diphosphorylase/ D-glycero-β-D- phosphatidate thymidine in DNA hexan-1-imine 3-yl)-L-cysteine cytosol nonspecific 1-phosphate dTDP-4- SM255186_RS13380 sn-glycerol L-lysine 3-mercaptopyruvate deoxyribodipyrimidine acetyl-coenzyme 3-phosphate 1-acyl-sn-glycerol- thiosulfate cystathionine orotate cystathionine 2-yl)-L-cysteinecystathionine Dcp substratepeptidyl- dethiobiotin synthase: bifunctional glucose- spermidine N1- phosphoglycerate mannose-1-phosphate glucosamine-1- manno-heptose cytidine deaminase: cytidylyltransferase: phosphatase: phosphatidylglycerophosphatase L-glyceraldehyde 3- dipeptidase: oligopeptidase B: aromatic amino nucleoside uridylyltransferase dehydrorhamnose 3-phosphate sulfurtransferase: A synthetase: sulfurtransferase: phosphoribosyltransferase: beta-lyase: dipeptidase Dcp: SM255186_RS04000 acylphosphatase: 1-phosphatase/ acetyltransferase: guanylyltransferase/ SM255186_RS22500 C: yfhb photo-lyase: 3-phosphate beta-lyase: beta-lyase: phosphate reductase: triphosphatase: mutase: 3,5-epimerase: rfbC phosphate N- 1-phosphate SM255186_RS11565 phosphatidate SM255186_RS01130 SM255186_RS22270 SM255186_RS20205 dethiobiotin synthase: SM255186_RS01700 SM255186_RS05330 SM255186_RS09845 acid transaminase: GalU: galU IMP dehydrogenase: dGTP superpathway of pyrimidine deoxyribonucleoside salvage a (2E)-hexadec- cardiolipin biosynthesis I SM255186_RS13415 phosphate [+ 2 isozymes] SM255186_RS03615 acyltransferase: SM255186_RS21255 SM255186_RS16250 SM255186_RS16250 4-methyl-4-SM255186_RS16250 SM255186_RS07600 SM255186_RS12745 inositol phosphatase: speG nudI SM255186_RS20355 mannose-6- acetyltransferase bifunctional heptose cytidylyltransferase: a CDP- a 2'-deoxycytidine an unsulfurated (E)-ω-(methylsulfanyl) 3-sulfanylpentan- SM255186_RS22120 dTDP-4-dehydro- CMP 2-enoyl-[acp] SM255186_RS16320 pyruvate orotate pyruvate SM255186_RS07715 L-glyceraldehyde met gly SM255186_RS05525 N 1 - UTP--glucose- phosphate isomerase: GlmU: glmU guaB uridine 1-oleoyl-2-palmitoyl- a thymidine in DNA isovaleryl-CoA AMP diphosphate 1-palmitoyl- thiocyanate PRPP pyruvate sulfanylpentan- a dipeptide a peptide an aromatic a nucleoside 3-phospho- β-L-rhamnose 7-phosphate kinase/ 2'-deoxycytidine SM255186_RS01130 diacylglycerol a CDP- hydrogen sulfide in DNA [sulfur carrier] hexyl-thiohydroximate 1-ol dethiobiotin a carboxylate a peptide 1-phosphate SM255186_RS10985 phosphatidylglycerol acyl-carrier protein 2-myristoyl 2-one 3-phosphate myo-inositol 2-oxo-acid acetylspermidine diphosphate D-glycerate dTDP-4- N-acetyl-α-D- heptose 1-phosphate uridine kinase: a CDP- CDP-diacylglycerol-- diacylglycerol uridylyltransferase: CDP-diacylglycerol-- phosphatidate phosphoglycerate D-mannopyranose dehydrorhamnose glucosamine adenyltransferase: cytidine deaminase: SM255186_RS11180 diacylglycerol glycerol-3-phosphate 3- Secondary Metabolite Degradation SM255186_RS11060 6-phosphate glycerol-3-phosphate 3- kinase: reductase: 1-phosphate SM255186_RS16455 SM255186_RS11565 CDP-diacylglycerol-- phosphatidyltransferase: Detoxification β XMP UMP phosphatidyltransferase: α a dimer of non-adjacent a 1-palmitoyl-2- 1-cis-vaccenoyl- a reduced (Z)-1-(L-cystein-S a dimer of adjacent an N-terminal- 3-[(4'- SM255186_RS15750 UDP-α-D-glucose phosphomannomutase SM255186_RS11050 bifunctional UDP-N- ADP-D-glycero- - dCMP a palmitoyl-[acp] glycerol-3-phosphate 3- SM255186_RS10175 anhydromuropeptides recycling I UDP-N-acetyl- -D-muramoyl- MoO - glycyl-L- asp SM255186_RS10175 superpathway of D-glucarate D-alanyl-D-alanine a cis- + + 2-succinylbenzoate coenzyme A 3-phenyl-2- 2 uroporphyrinogen-I an oligopeptide spermidine citrate CpsG: β D-manno-heptose 2'-deoxyuridine 1-(3-sn- L-alanyl-γ-D-glutamyl-L-lysine thymidine and 2'- hν acyl-sn-glycero-3- lipid IV (E. coli) sn-glycerol- ferredoxin [iron- NADP H -yl)-N-hydroxy-2- pyrimidine hν tyr L-allo-threonine asparagine L-methionyl- Ins(5)P methylsulfanyl) dTDP- -L- acetylglucosamine phosphatidyltransferase: 1-(3-sn- A vaccenoyl-[acp] oxopropanoate molybdopterin ATP cytidylate kinase: phosphatidyl) and D-galactarate degradation reactive oxygen species degradation UDP-N-acetylmuramoyl- deoxycytidine in DNA phosphocholine 3-phosphate sulfur] cluster phenylethan-1-imine o-succinylbenzoate- nucleosides in DNA cytosol nonspecific glycyl-[protein] butyl]malate aconitate 13-DPG SM255186_RS10980 rhamnose diphosphorylase/ ADP-L-glycero-D- GMP synthase: SM255186_RS10175 phosphatidyl) GlcNAc-1,6- superoxide 8-oxo-(d)GTP detoxification I deoxyribodipyrimidine lipid IV(A) 1-acyl-sn-glycerol- ferredoxin--NADP(+) cystathionine deoxyribodipyrimidine aromatic amino low-specificity L- cofactor uroporphyrinogen methionine bifunctional glucose- spermidine N1- UDP-glucose UDP-glucose 6- SM255186_RS04700 -sn-glycerol sulfoquinovose degradation I -CoA ligase: molybdenum cofactor dipeptidase: oligopeptidase A: 3-isopropylmalate hydratase phosphomannomutase glucosamine-1- mannoheptose- SM255186_RS12915 adenylosuccinate thymidine kinase: 1-(3-sn- -sn-glycerol anhMurNAc- radicals degradation tripeptide--D-alanyl- photo-lyase: palmitoyltransferase 3-phosphate reductase: beta-lyase: photo-lyase: acid transaminase: threonine aldolase: decarboxylase: aminopeptidase: 1-phosphatase/ acetyltransferase: 4-epimerase: dehydrogenase: 3-phosphate γ D-glucarate D-galactarate SM255186_RS12155 guanylyltransferase: SM255186_RS01700 SM255186_RS20925 dehydrogenase: AcnA: acnA triose-phosphate CpsG: phosphate N- 6-epimerase: synthetase: purA SM255186_RS06315 dCDP phosphatidyl) 3-phosphate L-Ala- -D-Glu- superoxide D- alanine ligase: SM255186_RS03615 PagP: acyltransferase: an oxidizedSM255186_RS18670 SM255186_RS16250 SM255186_RS03615 3-(4-SM255186_RS22120 SM255186_RS04480 SM255186_RS18270 map inositol phosphatase: speG SM255186_RS03895 SM255186_RS10960 phosphatidylglycerophosphatase a 2'-deoxycytidine (Z)-2-phenyl-1- 4-(2'-carboxyphenyl) two adjacent pyrimidine adenylyl mobA leuB palmitate phosphatidylglycerophosphatase DAP-D-Ala α superoxide phenylmercury acetate degradation dGTP GTP SM255186_RS00650 SM255186_RS16320 asn gly an N-terminal SM255186_RS05525 N 8 - [+ 2 isozymes] isomerase: SM255186_RS11090 acetyltransferase SM255186_RS20325 thymidine nucleoside- -sn-glycerol 1-(6-sulfo- -D-quinovosyl)glycerol UDP-N-acetyl-α-D-muramoyl-L-alanyl- a thymidine in DNA SM255186_RS03240 1,2-dicis- NADPH ferredoxin [iron- pyruvate -4-oxobutyryl-CoA phe hydroxyphenyl) acetaldehyde gly molybdenum met 7-(methylsulfanyl) α GMP dUMP A: SM255186_RS02175 A: SM255186_RS02175 superoxide in DNA a 2-acyl-sn-glycero- thioacetohydroximate nucleosides in DNA coproporphyrinogen I glycyl-[protein] a peptide SM255186_RS18685 D-glyceraldehyde UDP-α-D- UDP- -D- α GlmU: glmU ADP-L-glycero-β- adenylo-succinate 3-phosphate glucarate L-talarate/galactarate superoxide γ lipid IV acyl-carrier protein vaccenoyl- sulfur] cluster pyruvate myo-inositol acetylspermidine D-threo-isocitrate -D-mannose diphosphate kinase: dismutase [Mn]: -D-glutamyl-L-lysyl-D-alanyl-D-alanine B cofactor -2-oxoheptanoate DHAP long-chain-fatty- [+ 2 isozymes] [+ 2 isozymes] N-acetylmuramoyl- mercuriphenyl 3-phosphocholine 3-phosphate galactose glucuronate 1-phosphate trehalose UDP-N-acetyl- D-manno-heptose thymidine kinase: superpathway of guanine and guanosine salvage phosphatidylglycerophosphatase dehydratase: gudD dehydratase: dismutase [Mn]: phosphatidate thymidylate synthase: SM255186_RS13380 acid--CoA ligase: an L-1- an L-1- L-alanine SM255186_RS18815 acetate biosynthesis V α-D-glucosamine guanylate kinase: adenylosuccinate lyase: SM255186_RS06315 A: SM255186_RS02175 glucarate dehydratase: SM255186_RS20390 SM255186_RS18815 8-oxo-dGTP 8-oxo-GTP SM255186_RS15305 dCTP SM255186_RS09530 phosphatidyl- phosphatidyl- amidase [+ 2 isozymes] SM255186_RS20170 SM255186_RS06150 [+ 2 isozymes] 6-sulfo-α-D-quinovose SM255186_RS15085 [+ 2 isozymes] [+ 2 isozymes] sn-glycerol sn-glycerol hydrogen a [formate C a methylated (E)-1-(L-cystein-S- (E)-1-(L-cystein-S-yl)-N- a dimer of non- a 2'- a [protein]-L- 3-[(6'- a peptide with a glycogen acyl-CoA an L-1- AmiB: amiB hydrogen 8-oxo-dGTP a reduced glutathione 2-bromo-3-(4- an L-phenylalanyl- an N-terminal a 7,8-dihydro-8- L-selenocystathionine L-cysteinylglycine DNA with lesion guanosine cardiolipin synthase A: peroxide SAM acetyltransferase]- nucleobase 2-oxoglutarate yl)-N-hydroxy-2-(1H- hydroxy-ω-(methylsulfanyl) adjacent pyrimidine hν triphosphate deoxyribonucleoside 5-aminopentanal reduced riboflavin Ins(4)P methylsulfanyl) an N-terminal class II fructose- GDP-α-D- synthetase phosphatidyl- [+ 3 isozymes] peroxide diphosphatase nitrophenyl)propanoate [tRNA Phe ] oxoguanine in DNA β-isoaspartate flavodoxin glutathione S- arginyl-[protein] cystathionine 5'-monophosphate cytosol nonspecific hexyl]malate excinuclease bisphosphate aldolase: CDP-4-dehydro-3,6-dideoxy- mannose GDP AMP FdrA: fdrA sn-glycerol SM255186_RS06370 5-dehydro-4-deoxy-D-glucarate catalase- glycine pyruvate formate lyase within DNA DNA oxidative leucyl/phenylalanyl- indol-3-yl)ethan-1-iminecystathionine octan-1-iminecystathionine formamidopyrimidine- nucleosides in DNA deoxyribodipyrimidine inorganic NAD(P)H-flavin protein-L-isoaspartate bifunctional glucose- L-methioninemethionine trehalose biosynthesis I 2+ MutT: mutT 3-isopropylmalate SM255186_RS15745 D-glucose biosynthesis dTMP N-acetyl-β-D- L-alanyl-γ-D- peroxidase: Hg benzene acetate transferase: DNA glycosylase: triphosphatase: beta-lyase: aminobutyraldehyde dipeptidase: ABC subunit GDP- a maltodextrin 6-sulfo-D-quinovose autoinducer AI-2 degradation catalase- 8-oxo-GMP 1-activating protein: demethylase tRNA--protein beta-lyase: beta-lyase: photo-lyase: 5'-deoxynucleotidase: reductase: O-methyltransferase: 1-phosphatase/ dehydrogenase: aminopeptidase: adenine and purine-nucleoside palmitoyl-CoA Ptd Gro katG 8-oxo-dGMP SM255186_RS20465 SM255186_RS20240 SM255186_RS16250 dehydrogenase: patD SM255186_RS01700 A: uvrA α-D-glucopyranose mannose 4,6- D-glucopyranose thymidylate kinase: superpathway of pyrimidine 2 glucosamine-1,6- glutamyl-meso-2,6- peroxidase: SM255186_RS04650a [formate C AlkB: alkB transferase: SM255186_RS16250 SM255186_RS16250 SM255186_RS03615 SM255186_RS16465 SM255186_RS12290 SM255186_RS17505 SM255186_RS14850 inositol phosphatase: map α ribonucleoside- adenylate kinase: sulfoquinovose mercury(II) reductase: a nucleobase (E)-ω-(methylsulfanyl) an apurinic site 7,8-dihydro- seleno-L- β leuB 1-phosphate malto- UDP- -D-glucose adenosine salvage V nucleobases salvage phosphorylase: anhydro-N-acetyl- diaminopimeloyl- katG a flavodoxin [+ 3 isozymes] SM255186_RS04580 (E)-2-(1H-indol-3-yl)- a pyrimidine phosphate pyruvate gly cys a protein L- - SM255186_RS05525 [+ 3 isozymes] dehydratase: 6-phosphate diphosphate reductase: SM255186_RS02555 SM255186_RS05990 O met 5'-deoxyadenosine acetyltransferase]- succinate formaldehyde 2-(glutathion-S-yl)-3-(4- pyruvate pyruvate within DNA 8-oxoguanine diphosphate a 2'- 9-(methylsulfanyl) a peptide met DNA without glucose-1-phosphate CDP-tyvelose trehalose-6- deoD β isomerase: AI-2 H O hydroxyl radical 2 SM255186_RS19665 semiquinone within DNA L-phenylalanyl-L- 1-thioacetohydroximate octyl-thiohydroximate nucleoside in DNA homocysteine 5-aminopentanoate riboflavin isoaspartate β oligosyltrehalose -D-muramate D-alanine 2 bromide Phe myo-inositol -D-fructose 1,6- gmd SM255186_RS12010 uracil tartronate semialdehyde glycin -2-yl radical nitrophenyl)propanoate a tRNA deoxyribonucleoside -2-oxononanoate lesion cytidylyltransferase: synthase: treY biosynthesis phosphate synthase: dTDP muramoyltetrapeptide SM255186_RS19000 autoinducer-2 kinase: arginyl-[protein] α-methyl ester bisphosphate GDP-4-dehydro- nucleoside- SM255186_RS12015 inosine/ beta-hexosaminidase: 0 SM255186_RS10095 adenine uracil SM255186_RS18730 O Hg rfbF CDP-4-dehydro- α,α-trehalose diphosphate kinase: ADP nucleoside- guanosine kinase: carboxypeptidase: (4S)-4-hydroxy-5- 2 fructose 1,6- CDP-α-D-glucose α-D-rhamnose a maltooligosyl- purine-nucleoside phosphoribosyltransferase: SM255186_RS06035 2-hydroxy-3- SM255186_RS13380 diphosphate kinase: guanine SM255186_RS09440 6-deoxy-6-sulfo-D-fructose phosphooxypentane- bisphosphatase: trehalose 3,6-dideoxy- 6-phosphate SM255186_RS13240 SM255186_RS02570 oxopropionate GDP-L-fucose synthase: ribonucleoside- phosphorylase: 1,6-anhydro-N- L-alanyl-γ-D- an (S-diacyl-sn- cyclic a thiocarboxylated 2,3,5,6- 3-benzyl-3,6-dihydroxy- (E)-1-(L-cystein-S-yl)-N- a dimer of S-(1- a CDP- a [glycerolipid]- 3-hydroxy-5- an N-acyl-D- a [protein]-L- 3-[(5'- an adenosine 34 CDP-glucose 4,6- α-D-glucoseCDP-paratose ribonucleoside- ribonucleoside- SM255186_RS13380 2,3-dione an L-1- glutathione glycyl-L-proline SM255186_RS23795 malto- trehalose-phosphatase: deoD UMP hypoxanthine β reductase: glyceryl)-L-cysteinyl- 6-(hydroxymethyl) glutathione ω F6P ν uroporphyrinogen-III methylsulfanyl) (S)-malate Arg2 dehydratase: rfbG SM255186_RS11110 diphosphate reductase acetyl- -muramate glutamyl-meso- pyranopterin [SAMP] C- tetrachlorohydroquinone hydroxy- -(methylsulfanyl) glutathione hypoglycin A non-adjacent h hydroxyhexan- diacylglycerol oleate methyl-benzoate mannosamine methionine in [tRNA ] synthase: diphosphate reductase diphosphate reductase: SM255186_RS02715 (4S)-4-hydroxy-5- phosphatidylethanolamine cytosol nonspecific GDP-4-dehydro- oligosyltrehalose SM255186_RS10100 subunit alpha: dTTP adenosine UMP kinase: phosphoribosyltransferase: anhydro-N- diaminopimelate [apolipoprotein] apolipoprotein N- phosphate terminal glycine glutathione S- -diketopiperazine glutathione S- pentan-1-imine fructose-6- thymidines in DNA 3-yl)-L-cysteine CDP-diacylglycerol cyclopropane fatty acyl uroporphyrinogen-III 3-hydroxybenzoate N-acetylmannosamine peptide-methionine pentyl]malate fumarate hydratase: tRNA F6P CDP-4-dehydro-6- α SM255186_RS11015 subunit alpha: SM255186_RS12010 phosphonooxypentane- molybdopterin synthase cystathionine gamma- deoxyribodipyrimidine cystathionine 3-isopropylmalate 6-deoxy-β- trehalohydrolase: CDP- -D- SM255186_RS12010 SM255186_RS01110 SM255186_RS00890 2-hydroxy-3- acyltransferase: transferase: transferase: phosphate pyrophosphatase: dipeptidase: kinase: adenosine(34) deoxy-α-D-glucose α,α-trehalose SM255186_RS12010 SM255186_RS12015 acetylmuramic 2,3-dione isomerase: catalytic subunit: beta-lyase: glutamyltransferase: photo-lyase: beta-lyase: phospholipid synthase: C-methyltransferase: 6-monooxygenase: (S)-S-oxide reductase: dehydrogenase: SM255186_RS22405 treZ paratose Amine and Polyamine Biosynthesis 6-deoxy-6-sulfo-D-fructose 1-phosphate oxopropionate SM255186_RS20465 aldolase: fsa SM255186_RS18770 SM255186_RS01700 SM255186_RS17140 deaminase glucose-6-phosphate CDP-6-deoxy-delta-3,4- L-galactose adenosine deaminase: cytidylate kinase: xanthine acid kinase: SM255186_RS18695 SM255186_RS03400an N-acyl-(S-diacyl- SM255186_RS04050 SM255186_RS20465 SM255186_RS16250 SM255186_RS21160 SM255186_RS03615 SM255186_RS16250 a 1,2-diacyl- SM255186_RS08315 SM255186_RS17730 SM255186_RS11525 SM255186_RS23760 [+ 2 isozymes] CDP-paratose GTP ATP a 2-acyl-1-lyso- a [SAMP] C- (E)-ω-(methylsulfanyl) D-glyceraldehyde 3-sulfanylhexan- an N-acyl-α-D- leuB isomerase: GDP-L-fucose synthase: α α SM255186_RS04700 phosphoribosyltransferase: pyrimidine SM255186_RS08210 reductase: 3-hydroxy-5- sn-glyceryl)-L- [+ 3 isozymes] [+ 3 isozymes] dihydroxyacetone CMP sn-glycerol a [glycerolipid]- pro gly a protein-L- TadA: tadA glucoseen reductase: , -trehalose dGDP dADP SM255186_RS08120 molybdopterin 3-benzyl-3,6 -bis(glutathione) pyruvate L-cysteinylglycine hypoglycin B 3-phosphate a thymidine in DNA pyruvate 8-(methylsulfanyl) an inosine 34 2-epimerase: GMP SM255186_RS01705 spermidine biosynthesis III N-acetyl-D- SM255186_RS16705 phosphooxypentane- phosphatidylethanolamine terminal glycine 2,3,5-trichloro-6-(glutathion- pentyl-thiohydroximate 1-ol precorrin-2 3-methylgentisate mannosamine methionine- fumarate SM255186_RS21985 SM255186_RS11035 SM255186_RS11110 nucleobases salvage II spermidine biosynthesis I sulfofructosephosphate cysteinyl-[lipoprotein] 3-phosphate dihydrosterculate Arg2 UDP putrescine S-yl)-hydroquinone - 6-(hydroxymethyl) 6-phosphate -2-oxooctanoate in [tRNA ] SM255186_RS11010 muramate 6- aldolase: 2,4-dione C1 Compound Utilization and Assimilation (S)-S-oxide D-glucopyranose CDP-4-dehydro-3,6- cytosine biosynthesis I (R)-glycerate -diketopiperazine GDP-β-L-fucose α anaerobic anaerobic inosine nucleoside- phosphate 6-phosphate dideoxy-α-D-glucose CDP- -tyvelose cytosine deaminase: SM255186_RS18995 3-hydroxy-5- ribonucleoside- nucleoside- nucleoside- ribonucleoside- diphosphate kinase: arg SAM SAM N-acetylmuramic SM255186_RS17130 arg glycerate 2- phosphonooxypentane- formaldehyde oxidation triphosphate reductase: diphosphate kinase: diphosphate kinase: triphosphate reductase: acid 6- formate assimilation into 5,10- formaldehyde oxidation a single (E)-1-(L-cystein-S-yl)-N- a 2,3,4-saturated a dimer of adjacent 2'- a [peptide] a cytosine 967 3-hydroxy-4- 3-[(3'- a [protein]- inosine/ SM255186_RS13380 uracil S-adenosylmethionine 2,4-dione thiolase LsrF: VII (THF pathway) 5-amino-4- an (R)-2- an L-phenylalanyl- an N-terminal ν (2E,6E)-farnesyl an S-alkyl- N-acetyl- L-alanyl-L-leucine maltose an organic SM255186_RS23885 SM255186_RS13380 SM255186_RS13380 SM255186_RS23885 S-adenosylmethionine 3-sulfolactaldehyde DHAP kinase: garK methylenetetrahydrofolate II (glutathione-dependent) PRPP hydroxy-ω-(methylsulfanyl) CTP 1,2-diacyl-sn- h protoheme with N-terminal methylsulfanyl) thiosulfate N-phospho- guanosine kinase: decarboxylase phosphate SM255186_RS18700 stranded DNA imidazolecarboxyamide halocarboxylate [tRNA Phe ] deoxycytidines in DNA diphosphate in 16S rRNA methyl-benzoate hydroperoxide UTP decarboxylase exodeoxyribonuclease L-lysyl-[protein] L-cysteine L-citrulline cytosol nonspecific SM255186_RS02570 uracil etherase: murQ adenine HAD family hydrolase: leucyl/phenylalanyl- heptan-1-imine glycerol 3-phosphate deoxyribodipyrimidine protoheme IX β aspartate acetylornithine 16S rRNA m5C967 3-hydroxybenzoate maltose O- alkyl hydroperoxide propyl]malate thiosulfate L-histidine proenzyme: sulfolactaldehyde 2-phospho-D-glycerate formaldehyde cystathionine phosphatidate beta-aspartyl-peptidase: cystathionine 3-isopropylmalate phosphohistidine CTP synthetase: phosphoribosyltransferase: proenzyme: N-acetyl-D- DHAP formate formaldehyde VII large subunit: phosphoribosyltransferase: SM255186_RS04235 photo-lyase: farnesyltransferase: dipeptidase: acetyltransferase: reductase: SM255186_RS00865 agmatine tRNA--protein beta-lyase: cytidylyltransferase: SM255186_RS24305 beta-lyase: deacetylase: methyltransferase: 6-monooxygenase: sulfurtransferase: agmatine SM255186_RS00865 cadaverine biosynthesis 3-reductase: SM255186_RS13305 SM255186_RS02530 SM255186_RS03615 SM255186_RS01700 dehydrogenase: phosphatase dGTP dATP IMP SM255186_RS15000 SM255186_RS13240 putrescine dAdoMet glucosamine HAD family hydrolase: transferase: SM255186_RS16250 SM255186_RS01130 SM255186_RS02285 SM255186_RS16250 SM255186_RS18500 SM255186_RS21820 SM255186_RS11525 SM255186_RS02475 SM255186_RS03125 SM255186_RS21255 SM255186_RS18990 a single-stranded a ribonucleoside ω two adjacent 2'- α leuB SixA: sixA agmatinase: 6-phosphate AICAR SM255186_RS04325 SM255186_RS04580 (E)- -(methylsulfanyl) a CDP-2,3,4-saturated- a peptide asp 967 6-O-acetyl- -D- ahpF CTP UMP dAdoMet a 5,10- pyruvate deoxycytidines in DNA ferroheme o pyruvate an alkyl-thiol acetate L-citrulline a 5-methylcytosine leu ala 6-(methylsulfanyl) a [protein]- speB a 10- S-(hydroxymethyl) oligodeoxyribonucleotide 5'-monophosphate an (S)-2- L-phenylalanyl- heptyl-thiohydroximate diacylglycerol 4-methylgentisate glucopyranosyl- sulfite lys N-acetylglucosamine- 3-sulfopropanediol methylenetetrahydrofolate a halide anion a tRNA Phe in 16S rRNA an alcohol formyltetrahydrofolate glutathione hydroxyarboxylate (1->4)-D-glucose -2-oxohexanoate L-histidine polyamine 6-phosphate bifunctional L-lysyl-[protein] putrescine lysine decarboxylase LdcC: bifunctional glutathione-dependent aminopropyltransferase: spermidine deacetylase: D-glucarate degradation II methylenetetrahydrofolate SM255186_RS01195 4-deoxy-L-threo-hex-4- methylenetetrahydrofolate formaldehyde SM255186_RS00870 SM255186_RS03480 dehydrogenase/ lysine decarboxylase CadA: enopyranuronate degradation dehydrogenase/ dehydrogenase: (2-hydroxyphenyl)methyl 1-hydroxy- an (S)-2- a [DNA]-3'- a 5'-phospho- (E)-1-(L-cystein-S-yl)-N- (E)-1-(L-cystein-S-yl)-N-hydroxy- S-(2-hydroxyacyl) a 5' triphospho- a double (5Z)- a uracil 1939 (2R,3S)-3- D-glucosamine methenyltetrahydrofolate a peptidoglycan NAD + S-benzyl- glycyl-L-glutamate cobalt-precorrin-2 a D-hexose DHAP S-methyl-5'- N 1 -(3-aminopropyl) SM255186_RS13550 D-glucarate methenyltetrahydrofolate SM255186_RS03170 [DNA] hydroxy-ω-(methylsulfanyl) ω glutathione VibB coenzyme A a tRNA precursor stranded DNA dodecenoyl-CoA isopropylmalate 6-phosphate 4-deoxy-L-threo-hex- cyclohydrolase FolD: folD 6-oxocyclohex-2-ene-1-carboxylate halocarboxylate hydroxyl -(methylsulfanyl)butan-1-imine L-cysteine [mRNA] in 23S rRNA cadaverine glucarate N-acetylmuramoyl-L- carboxylesterase/ HAD family hydrolase: DNA ligase nonan-1-imine cystathionine hydroxyacylglutathione cytosol nonspecific 23S rRNA thioadenosine agmatine 4-enopyranuronate cyclohydrolase FolD: folD cystathionine holo-ACP synthase: ribonuclease D: cystathionine RNA cobalt-factor II C(20) acyl-CoA glucokinase: 3-isopropylmalate phosphoglucosamine dehydratase: a 5,10- S-formylglutathione alanine amidase AmiB: amiB lipase family protein: SM255186_RS04235 (NAD(+)) LigA: beta-lyase: hydrolase: DNA gyrase subunit B: dipeptidase: methylglyoxal beta-lyase: SM255186_RS09525 beta-lyase: pyrophosphohydrolase: -methyltransferase: dehydrogenase: (uracil(1939)-C(5)) SM255186_RS12725 dehydrogenase: mutase: a 5,10- SM255186_RS13640 SM255186_RS19475 synthase: mgsA gudD methenyltetrahydrofolate [+ 3 isozymes] SM255186_RS07050 HAD family hydrolase: SM255186_RS12865 SM255186_RS16250 SM255186_RS01340 SM255186_RS15320 SM255186_RS01700 SM255186_RS10660 SM255186_RS01665 -methyltransferase leuB SM255186_RS16925 5-dehydro-4-deoxy- methenyltetrahydrofolate 1-hydroxy-6-oxocyclohex- SM255186_RS16250 (E)-ω-(methylsulfanyl) a 2-hydroxy a holo-[VibB aryl- a nucleoside 5'- SM255186_RS16250 glucarate dehydratase: bifunctional S-formylglutathione ditrans,octacis-undecaprenyldiphospho- salicyl alcohol SM255186_RS04325 (E)-ω-(methylsulfanyl) pyruvate glutathione 3',5'-ADP a tRNA RlmD: rlmD D-glucuronate a peptidoglycan pentapeptide pyruvate carrier protein] monophosphate pyruvate benzyl thiol a 5'-phospho- a negatively glu gly (2E,5Z)- 1939 D-hexose 6- 4-methyl-2- α-D-glucosamine bifunctional hydrolase: fghA formate oxidation to CO N-acetyl-(N-acetylglucosaminyl)muramate 2-ene-1-carboxylate an (S)-2- NMN AMP [DNA] nonyl-thiohydroximate butyl-thiohydroximate carboxylate cobalt-precorrin-3 a 5-methyluracil methylglyoxal SM255186_RS15085 methylenetetrahydrofolate 2 a halide anion phosphate spermidine 5-keto-4-deoxyuronate 5-dehydro-4- methylenetetrahydrofolate [mRNA] supercoiled DNA dodecenoyl-CoA oxopentanoate 1-phosphate galactitol degradation dehydrogenase/ hydroxyarboxylate in 23S rRNA isomerase: deoxy-D-glucarate dehydrogenase/ formate bifunctional UDP-N- methenyltetrahydrofolate formate SM255186_RS15415 methenyltetrahydrofolate acetylglucosamine galactitol cyclohydrolase FolD: folD formate dehydrogenase 3-deoxy-D-glycero- cyclohydrolase FolD: folD a [glycine-cleavage 13-sophorosyloxydocosanoate an (S)-2- (3,4-dihydroxyphenyl) an N-formyl-L- an [RNA] all-trans- L-alanyl-L- an N-hydroxy- L-gulono- (2R,3S)-3- diphosphorylase/ N subunit alpha, methyl red [DNA] 4-nitrocatecholsulfate 3-mercaptopyruvate hydroxypyruvate gentisate a 10- SAM complex H protein] a sulfurated [sulfur carrier] 6',6''-diacetate halocarboxylate methionylaminoacyl- containing retinyl palmitate S-ethyl-L-cysteine glutamine arylamine thr 1,4-lactone isopropylmalate glucosamine-1- 2,5-hexodiulosonate 2,5- a 5,10- acetate formyltetrahydrofolate selenocysteine-containing: N 6 -octanoyl-L-lysine acetylesterase: HAD family hydrolase: tRNA FMN-dependent exodeoxyribonuclease cytidine carboxylesterase/ cytosol nonspecific SMP-30/ 2-dehydro- galactitol 1- methylenetetrahydrofolate peptide deformylase: ribonuclease I: cystathionine sulfatase: 3-mercaptopyruvate N-hydroxyarylamine hydroxypyruvate 3-isopropylmalate gentisate 1,2- phosphate N- dioxopentanoate SM255186_RS22320 lipoyl SM255186_RS02565 SM255186_RS04235 3,4-dihydroxyphenylacetate NADH-azoreductase: I: SM255186_RS10885 lipase family protein: dipeptidase: L-threonine 3- gluconolactonase/ phosphate formyltetrahydrofolate β β beta-lyase: SM255186_RS00165 sulfurtransferase: O-acetyltransferase: isomerase: dehydratase: dioxygenase: acetyltransferase 3-deoxy-D- CO synthase: lipA 13-[O(2')- -D-glucopyranosyl- -D- 2,3-dioxygenase: hpaD SM255186_RS21830 a 2'- SM255186_RS03180 SM255186_RS01700 dehydrogenase: superpathway of β-D- 2 a [glycine-cleavage HAD family hydrolase: SM255186_RS06985 a 5'-hydroxy- an [RNA]-3'- SM255186_RS07050 SM255186_RS13415 SM255186_RS07265 SM255186_RS02710 LRE family protein: leuD leuC gtdA GlmU: glmU gluconate 5- galactitol-1-phosphate deformylase: purU an unsulfurated acetate glucopyranosyloxy]docosanoate a L-methionylaminoacyl- N,N-dimethyl-1,4- deoxyribonucleoside [DNA] SM255186_RS16250 [+ 2 isozymes] SM255186_RS20335 5'-deoxyadenosine met complex H protein] SM255186_RS04325 2-hydroxy-5- formate ribonucleotide- cytidine-3'- palmitate all-trans-retinol SM255186_RS13850 glucuronosides degradation dehydrogenase 5-dehydrogenase: [sulfur carrier] O(6'')-acetate tRNA anthranilate 5'-monophosphate pyruvate ethanethiol gln ala an N- tartronate (2S)-2- N-acetyl-α-D- N 6 -lipoyl-L-lysine a (2R)-2- carboxymethylmuconate phenylenediamine 4-nitrocatechol pyruvate 3-maleylpyruvate SM255186_RS16770 formate a halide anion 3'-[RNA] phosphate acetoxyarylamine semialdehyde aminoacetone L-gulonate isopropylmalate glucosamine a β-D-glucuronoside KduD: kduD 2-oxoglutarate hydroxy fatty acid semialdehyde 1-phosphate 2-dehydro-3- keto-D-tagatose bifunctional UDP-N- deoxy-D-gluconate 6-phosphate an (R)-2- di-trans,octa-cis crotonobetainyl- β-aspartyl an all-trans RNase E degradation L-alanyl- a negatively D-ribulose a uridine 65 a uridine 516 an aliphatic acetylglucosamine D-glucopyranuronate a sulfurated fenamiphos α L-carnitine glutathione glycyl-glycine 2-oxoglutarate a 2'-deoxyribonucleoside 2-phosphoglycolate ethanol SAM dethiobiotin halocarboxylate UDP- -D-glucose -undecaprenyl CoA -retinyl ester [DNA] substrate mRNA L-histidine supercoiled DNA 5-phosphate in tRNA in 16S rRNA α,ω-diamine diphosphorylase/ [sulfur carrier] dipeptide 5'-triphosphate phosphotriesterase: HAD family hydrolase: phosphate L-carnitine CoA- gamma- beta-aspartyl-peptidase: carboxylesterase/ 2-oxoglutarate cytosol nonspecific biotin synthase: undecaprenyl- DNA polymerase phosphoglycolate DNA topoisomerase: tRNA 16S rRNA spermidine N1- catalase- glucosamine-1- D-tagatofuranose SM255186_RS04235 transferase: glutamyltransferase: lipase family protein: dehydrogenase E1 ribonuclease E: dipeptidase: phosphoribulokinase: SM255186_RS21165 phosphate glucose SM255186_RS24305 I: polA phosphatase: SM255186_RS21845 pseudouridine(65) pseudouridine(516) acetyltransferase: peroxidase: phosphate N- 6-phosphate SM255186_RS03985 3-methyl-4- SM255186_RS01700 SM255186_RS21535 KDGP ethoxy(isopropylamino) HAD family hydrolase: SM255186_RS00365 SM255186_RS21160 a proteinogenic SM255186_RS07050 component: sucA SM255186_RS05920 SM255186_RS21440 synthase TruC: truC synthase: rsuA speG katG acetyltransferase an unsulfurated (methylsulfanyl) phosphotransferase: γ-L-glutamyl- asp [+ 11 isozymes] [+ 4 isozymes] aldehydo-D-glucuronate met 5'-deoxyadenosine biotin phosphinate SM255186_RS04325 L-carnitinyl-CoA crotono-betaine L-cysteinylglycine amino acid a fatty acid all-trans-retinol NADH CO succinyl-CoA 65 [sulfur carrier] SM255186_RS11085 2 [DNA] his ala D-ribulose-1,5- a pseudouridine a 16S rRNA an aliphatic N- GlmU: glmU 2-dehydro-3-deoxy- Alcohol Degradation phenol a (2R)-2- α-D-glucopyranosyl- glycylglycine an mRNA fragment glycolate a relaxed DNA acetaldehyde a halide anion bisphosphate in tRNA pseudouridine 516 acetyl-diamine UDP-N-acetyl- glucuronate isomerase: phosphogluconate hydroxy fatty acid diphosphoundecaprenol UMP D-tagatofuranose α-D-glucosamine SM255186_RS16135 aldolase: (S)-propane-1,2-diol degradation SM255186_RS20030 1,6-bisphosphate glycerol and glycerophosphodiester degradation glycerol degradation II UDP-N-acetylglucosamine a peptidoglycan 2''-O-acetyl- 13 D-fructuronate tagatose-1,6- a [disulfide-bond a single- a 1-palmitoyl-2-acyl-sn- a dimer of adjacent an N-terminal-L-methionyl- an N-terminal-L-methionyl- (S)-2- a uridine D-glyceraldehyde (S)-propane- a protein with reduced trans-dienelactone [DNA] melibionate ν FMN + glycyl-L-aspartate β-D-allopyranose oxaloacetate 3-ethylmalate 1-carboxyvinyltransferase: carrier protein] carrying stranded RNA lipid A dimer (generic) h NAD(P)H H ADP-ribose L-cysteinyl-[protein] MeOH pyruvate bisphosphate aldolase: glycerol L-cysteine residues glycero-3-phosphocholine thymidines in DNA L-threonyl-[protein] hydroxyglutarate in tRNA murA fructuronate reductase: 3-phosphate 1,2-diol a glycerophosphodiester polyribonucleotide lipid IV(A) exodeoxyribonuclease lytic transglycosylase: alpha-glucosidase/ deoxyribodipyrimidine NAD(P)H-flavin O-acetyl-ADP- methionine methionine cytosol nonspecific SM255186_RS16730 a disulfide bond L-2-hydroxyglutarate tRNA 2-methylcitrate 3-isopropylmalate catalase- UDP-N-acetyl-α- glycerol DSBA oxidoreductase: carboxymethylenebutenolidase: SM255186_RS22635 alpha-galactosidase: ribose deacetylase: aminopeptidase: aminopeptidase: dipeptidase: D-ribose pyranase: SM255186_RS16130 propanediol nucleotidyltransferase: pnp palmitoyltransferase III: SM255186_RS08905 photo-lyase: reductase: oxidase: pseudouridine(13) synthase: dehydrogenase: peroxidase: D-glucosamine- D-glyceraldehyde dehydrogenase: SM255186_RS05515 SM255186_RS17565 a 2'- [+ 5 isozymes] SM255186_RS22395 SM255186_RS05695 SM255186_RS19225 DHAP D-galactarate dehydratase: a [disulfide-bond carrier a nucleoside a single- PagP: SM255186_RS03615 SM255186_RS17505 map map SM255186_RS01700 SM255186_RS01900 leuB D-mannonate 3-phosphate glycerophosphodiester SM255186_RS18530 a protein with deoxyribonucleoside [DNA] GlcNAc-1,6-anhydro- α-D- two adjacent SM255186_RS14145 synthase TruD: truD katG enolpyruvate degradation II SM255186_RS10740 protein] with reduced diphosphate stranded RNA SM255186_RS03240 + an N-terminal L- an N-terminal L- dihydroxyacetone a lipid II D-gluconate NAD(P) FMNH acetate ADP-D-ribose met met asp gly β a pseudouridine 13 (2S,3S)-2- glycerol phosphodiesterase: a disulfide bond a 2-acyl-sn-glycero- 5'-monophosphate MurNAc-pentapeptide galactopyranose thymidines in DNA 2 -D-allofuranose formaldehyde UDP-N- mannonate SM255186_RS10745 L-cysteine residues 2-maleylacetate lipid B (E. coli) cysteinyl-[protein] threonyl-[protein] 2-oxoglutarate 2-oxovalerate D-sorbitol degradation II SM255186_RS21150 in tRNA methylcitrate acetylenolpyruvoylglucosamine dehydratase: D-galactarate pduE 3-phosphocholine L-talarate/galactarate glycerol glycerophosphodiester reductase: SM255186_RS18410 uxuA D-sorbitol UDP-N-acetyl- mannitol degradation I dehydratase: 1-propanal kinase: phosphodiesterase: 2-dehydro-3- 6-phosphate an N-arachidonoyl- an α-D- a long-linear a 2'- methyl (indol- 3''-O-acetyl- L-alanyl-L- phosphoenol sorbitol-6-phosphate SM255186_RS12035 α a maltodextrin α-D- a 1,4-α-D-glucan a 1,4-α-D-glucan + α-D-muramate SM255186_RS20390 glpK DHAP indolylmethylisothiocyanate glutathione cis-dienelactone α-D-glucan -D-glucopyranose D-glucopyranose deoxyribonucleoside [DNA] a carboxylic ester ADP-ribose isovaleryl-CoA L-cysteate putrescine NAD deoxy-D-gluconate dehydrogenase: D-mannitol phosphatidylethanolamine galactoside 3-yl)acetate glucopyranose ATP aspartate pyruvate [+ 2 isozymes] 1-propanol glutathione S-transferase: alpha-glucosidase/ 4-alpha- 4-alpha- 5'-triphosphate carboxylesterase/ carboxylesterase/ O-acetyl-ADP- cytosol nonspecific UDP-N- SM255186_RS14395 1-phosphate 5-dehydro-4- phospholipase A(1): reverse transcriptase: 1-phosphate glycogen- isovaleryl-CoA glycogen- aspartate spermidine N1- keto-D-fructose mannitol-1-phosphate dehydrogenase PduQ: sn-glycerol SM255186_RS20465 alpha-galactosidase: carboxymethylenebutenolidase: glucanotransferase: glucanotransferase: lipase family protein: lipase family protein: ribose deacetylase: dipeptidase: NAD(+) kinase: pyruvate acetylmuramate:L- deoxy-D-glucarate SM255186_RS17615 SM255186_RS13980 glucose-1-phosphate branching enzyme: dehydrogenase: branching enzyme: aminotransferase: acetyltransferase: 6-phosphate 5-dehydrogenase: SM255186_RS10800 3-phosphate [+ 3 isozymes] an N-arachidonoyl-2-acyl-1- SM255186_RS22395 SM255186_RS17565 SM255186_RS21280 SM255186_RS21280 SM255186_RS07050 SM255186_RS07050 SM255186_RS05695 SM255186_RS01700 SM255186_RS13925 kinase: pyk alanyl-gamma-D- a fatty acid a short 1,4- adenylyltransferase: SM255186_RS21225 SM255186_RS23570 SM255186_RS21225 SM255186_RS04790 speG SM255186_RS20455 propanoyl-CoA a non α [DNA] α ethylene glycol degradation indol-3-ylmethylisothiocyanate-glutathione lysophosphatidylethanolamine -D- α maltose a maltodextrin MeOH (indol-3-yl)acetate a carboxylate an alcohol acetate ADP-D-ribose glgC a (1,6)- -D-glucosyl- glutamyl- meso- KDGP anaerobic glycerol- galactosylated -D-glucan asp ala 3-methylcrotonyl- a GlgE-glycogen + F6P galactopyranose 2-maleylacetate ADP-α-D-glucose (1,4)-α-glucan 3-sulfopyruvate N-acetylputrescine NADP pyruvate diaminopimelate phosphate 3-phosphate glycerol degradation V CoA 2,5- propan-1-ol galactose acceptor ligase: mpl 2-dehydro-3-deoxy- propanoyltransferase: dehydrogenase: ethylene glycol dioxopentanoate phosphogluconate pduL SM255186_RS12045 lactaldehyde glycerol UDP-N-acetyl- 5,10-methylene- 3-methyl-2- RNase III mRNA an [RNA] aldehydo-D- 2-keto-D- α aldolase: glpB glpC reductase: fucO glycerol isoprimeverose a proteinogenic maltopentaose D-glucopyranose maltotetraose D-glucopyranose hydrogencarbonate H + a phenol an aryl sulfate 2-oxoadipate O-ureido-L- glycyl-L-glutamine a 1,4-α-D-glucan myristoyl-CoA spermine AIRs (R)-glycerate -D-muramoyl- propanoyl tetrahydromethanopterin oxobutanoate processing substrate leukotriene-C4 containing uridine asp galacturonate gluconate SM255186_RS20030 lactaldehyde reductase: dehydrogenase: amino acid 4-alpha- 4-alpha- homoserine L-alanyl-γ-D- phosphate DHAP 3-methyl-2-oxobutanoate ribonuclease 3: carbonate dehydratase: ribonuclease I: aryl-sulfate 2-oxoglutarate cytosol nonspecific glycogen- alpha-xylosidase: gamma- argininosuccinate glucuronate isomerase: 2,5- acyl-CoA spermidine N1- aminoimidazole glycerate glutamyl-meso-2,6- D-glyceraldehyde SM255186_RS15155 SM255186_RS18530 hydroxymethyltransferase: SM255186_RS13660 glucanotransferase: glucanotransferase: SM255186_RS00895 SM255186_RS03180 sulfotransferase: dehydrogenase E1 dipeptidase: branching enzyme: pyruvate 2-oxoglutarate acetate/propionate glycolaldehyde dihydroxyacetone SM255186_RS20130 glutamyltransferase: a 5'-hydroxy- an [RNA]-3'- synthase: SM255186_RS16135 didehydrogluconate dehydrogenase: acetyltransferase: riboside kinase: 3-kinase: diaminopimelate 3-phosphate panB RNase III processing SM255186_RS21280 SM255186_RS21280 SM255186_RS16410 component: sucA SM255186_RS01700 SM255186_RS21225 family kinase: an mRNA fragment SM255186_RS21160 H O CO ribonucleotide- uridine-3'- SM255186_RS16910 reductase DkgB: dkgB SM255186_RS01665 speG SM255186_RS18760 glxK THMPT 2-dehydropantoate product mRNA an α-(γ-L-glutamyl) maltose maltotetraose maltose maltotriose 2 2 a phenol an aryl sulfate glutaryl-CoA NADH CO SM255186_RS10825 α-D-xylopyranose D-glucopyranose leukotriene-D4 phosphate 2 canavaninosuccinate D-tagaturonate gln gly 2,5-didehydro- a glycogen (2E)-tetradec- 1 3-phospho- -L-amino acid 3'-[RNA] N -acetylspermine AIR [+ 2 isozymes] D-gluconate 2-enoyl-CoA D-glycerate

propanoate glycolate DHAP α a 1-O-(alk-1-enyl)-sn-glycero- 3-[(3aS,4S,7aS)-7a-methyl- p-nitrophenyl- -D- a plant soluble a sophorosyloxyfatty a peptide with L-alanyl-L- 3-[(7'-methylsulfanyl) propane- γ + β D-sedoheptulose α ribulose Reactive Blue 5 1,5-dioxo-octahydro-1H coenzyme A galactopyranoside heteroglycan D-glucopyranose gly -L-glutamyl-(S)- stachyose FMNH NADP GSSH sulfite GDP- -L-fucose a 1,4- -D-glucan precorrin-8x Amino Acid Degradation 3-phosphoethanolamine acid O(6'')-acetate 2 an N-terminal threonine heptyl]malate 1,3-diamine alpha-glucosidase/ 4-alpha- 2-aminobutanoate alpha-glucosidase/ cytosol nonspecific Dyp-type peroxidase: lysoplasmalogenase: -inden-4-yl]propanoate acetylesterase: NAD(P)H-flavin thiosulfate L-alanine glycogen- 3-isopropylmalate spermidine N1- precorrin-8X acyl-CoA synthetase alpha-galactosidase: glucanotransferase: glutathione synthetase: alpha-galactosidase: GDP-L-fucose synthase: aminopeptidase N: dipeptidase: fructokinase: ribulokinase: SM255186_RS12955 SM255186_RS21045 SM255186_RS02565 reductase: sulfurtransferase: branching enzyme: dehydrogenase: acetyltransferase: methylmutase: L-threonine degradation I 3-[(4-amino-6-chloro- 3-[(3aS,4S,7aS)-7a-methyl-FdrA: fdrA SM255186_RS22395 SM255186_RS21280 SM255186_RS15865 SM255186_RS22395 SM255186_RS11110 SM255186_RS05180 SM255186_RS02025 araB L-histidine degradation I L-phenylalanine glycine cleavage 2,2'-disulfonyl sn-glycero-3- a sophorosyloxyfatty SM255186_RS17505 SM255186_RS21255 SM255186_RS01700 SM255186_RS21225 L-proline degradation L-arginine degradation 1,3,5-triazin-2-yl) phthalate a fatty aldehyde a plant soluble ophthalmate acetate α-D- leuB speG cbiC phosphoethanolamine 1,5-dioxo-octahydro-1H- maltose acid + GDP-4-dehydro- a peptide ala L(or D)-ribulose II (AST pathway) degradation II (anaerobic) azobenzene 4-nitrophenol D-galactopyranose heteroglycan raffinose H NADPH FMN thiosulfate glutathione thr ala D-sedoheptulose starch 10-(methylsulfanyl) N-(3-aminopropyl) amino]benzenesulfonate inden-4-yl]propanoyl-CoA galactopyranose α-D-rhamnose hydrogenobyrinate thr a [glycine-cleavage complex 1-phosphate -2-oxodecanoate acetamide 5-phosphate pro his H protein] N 6 -lipoyl-L-lysine serine/threonine arg phe histidine glycine cleavage dehydratase: trifunctional L-tyrosine degradation I aspartate glycine cleavage ammonia- system protein RNase E mRNA an N 3 -methyladenine a sophorosyloxyfatty acibenzolar- (25S)-3- transcriptional 1 maltotriose + α SM255186_RS16680 aminotransferase: system protein an N -methyladenine in DNA 2-oxoglutarate diazinon maltohexaose D-glucopyranose a ribonucleic acid raffinose FMN NADH H an -limit dextrin L-alanyl-glycine an L-cysteine- 5-methylcytosine an aryl sulfate oxocholest- coenzyme A putrescine D-ribulose 2 lyase: hutH H: gcvH processing substrate in DNA acid 6',6''-diacetate S-methyl F0F1 ATP regulator/proline N -succinyl- SM255186_RS04790 S-conjugate + + threonine urocanate H: gcvH DNA oxidative ribonuclease E: phosphotriesterase: DNA-3-methyladenine 4-alpha- ribonuclease PH: acetylesterase: alpha-glucosidase/ alpha-glucosidase: NAD(P)H-flavin carboxylesterase/ 4-alpha- cytosol nonspecific 4-en-26-oate acyl-CoA H H dehydrogenase/L- L-arginine tyr cystathionine sulfatase: putrescine ribulokinase: synthase ammonia- aromatic amino dihydrolipoyl demethylase AlkB: alkB SM255186_RS05920 SM255186_RS21165 glycosylase I: glucanotransferase: SM255186_RS20200 SM255186_RS02565 alpha-galactosidase: SM255186_RS19010 reductase: lipase family protein: glucanotransferase: dipeptidase: cytosine deaminase: synthetase glutamate gamma- aromatic amino urocanate 2-isopropyl-6- beta-lyase: SM255186_RS00165 aminotransferase: araB lyase, acid transaminase: dehydrogenase: RNase E processing SM255186_RS20695 SM255186_RS21280 a nucleoside a sophorosyloxyfatty SM255186_RS22395 [+ 2 isozymes] SM255186_RS17505 SM255186_RS07050 SM255186_RS21280 SM255186_RS01700 SM255186_RS17130 FdrA: fdrA semialdehyde acid transaminase: hydratase: succinate formaldehyde an adenine in DNA an mRNA fragment diethylthiophosphate methylpyrimidin- an apurinic site a ribonucleic acid acetate α-D- SM255186_RS16250 [+ 2 isozymes] (25S)-3- ygjG biosynthetic: SM255186_RS22120 product mRNA maltose maltopentaose diphosphate acid O(6'')-acetate + a α-limit dextrin dehydrogenase: 3-phenyl-2- lpdA a [glycine-cleavage 3-methyladenine sucrose D-glucopyranose maltose NAD FMNH MeOH acibenzolar gly ala pyruvate a thiol thymine oxocholest-4- D-ribulose SM255186_RS22120 hutU a [glycine-cleavage 4-ol within DNA galactopyranose 2 a phenol 1-pyrroline H + RS10305 H + ilvA 2 3-(4-hydroxyphenyl) 6 with short branches 5-phosphate N -succinyl- oxopropanoate 6 complex H protein] N - en-26-oyl-CoA (2Z)-2-aminobut- SM255186_RS05555 4-imidazolone- complex H protein] N (S)-1-pyrroline- L-ornithine pyruvate aminomethyldihydrolipoyl- 2-enoate 5-propanoate -dihydrolipoyl-L-lysine 5-carboxylate L-lysine succinylornithine a DNA containing α imidazolonepropionase: an L-1- a single a ribonucleoside a dipeptide with a (-)-methyl all-trans- L-methionyl-L- a glucosylated N-acetyl- - CTP aminotransferase: an N 1 -ethyladenine in DNA 2-oxoglutarate amino-parathion a 1,4-α-D-glucan canavaninosuccinate methylsalicylate 5-fluorocytosine D-glucopyranose an apurinic/ asp fumarate alanine dipeptide pimeloyl-CoA ala glycogenin neuraminate SM255186_RS08900 SM255186_RS03950 phenylacetaldehyde phosphatidylethanolamine stranded DNA triphosphate C-terminal L-proline jasmonate retinyl palmitate deoxycytidine DNA oxidative phospholipase A(1): phosphotriesterase: alpha-glucosidase: apyrimidinic site argininosuccinate lyase: Xaa-Pro dipeptidase: carboxylesterase/ carboxylesterase/ carboxylesterase/ cytosol nonspecific glycogen- N-acetylneuraminate xylose N 2 -succinyl- homogentisate endonuclease III: DNA primase: L-aspartate oxidase: 8-amino-7- triphosphate 2-iminobutanoate L-glutamate-5- N-formimino- demethylase AlkB: alkB SM255186_RS17615 SM255186_RS21165 SM255186_RS19010 SM255186_RS18485 SM255186_RS17480 lipase family protein: lipase family protein: lipase family protein: dipeptidase: cytosine deaminase: branching enzyme: epimerase: isomerase: L-glutamate 5- NAD-dependent D-serine SM255186_RS08175 SM255186_RS16510 SM255186_RS13710 oxononanoate deaminase: semialdehyde L-glutamate a 2-acyl-1-lyso- [+ 2 isozymes] ssDNA/pppN(pN) a proteinogenic SM255186_RS07050 SM255186_RS07050 SM255186_RS07050 SM255186_RS01700 SM255186_RS17130 SM255186_RS21225 SM255186_RS05590 xylA semialdehyde phenylacetaldehyde glycine cleavage degradation succinate acetaldehyde an adenine in DNA a fatty acid 4-aminophenol diethylthiophosphate a 5'-phospho- a 3'-terminal fumarate L-canavanine succinate 2-iminosuccinate pro synthase: bioF SM255186_RS11175 phosphatidylethanolamine D-glucopyranose a 1,4-α-D-glucan hybrid amino acid 8-amino-7- N-acetyl-β- dehydrogenase: system protein [DNA] unsaturated sugar n -1 MeOH (-)-jasmonate palmitate a retinol MeOH salicylate ala met coenzyme A 5-fluorouracil a glycogen keto-D-fructose trifunctional formimidoylglutamase: oxononanoate neuraminate UTP transcriptional SM255186_RS03955 SM255186_RS16090 H: gcvH 4-maleyl-acetoacetate D-serine 2-oxobutanoate regulator/proline aminomethyltransferase: N 2 - phenylacetate D-serine dehydrogenase/L- SM255186_RS15655 β β succinylglutamate maleylacetoacetate glu ammonia- a 2-acyl-1-lyso- 13-[O(2')- -D-glucopyranosyl- -D- RNase R degradation dUMP a dipetide with an N- an N 3 -methylcytosine in DNA 2-oxoglutarate coumaphos a phosphatidylcholine a 9S rRNA γ-L-glutamyl- a glucan maltotriose cadusafos an aryl dialkyl precorrin-2 Co 2+ β-D-fructofuranose xylan cellulose α-amylose D-altropyranose glutamate gamma- isomerase: maiA lyase: phosphatidylethanolamine glucopyranosyloxy]docosanoate substrate RNA gly terminal L-aspartate succinylglutamate L-serine degradation D-alanine 4-alpha- phosphate semialdehyde dsdA DNA oxidative lysophospholipase L2: O(6'')-acetate ribonuclease R: phosphotriesterase: phospholipase A(1): ribonuclease E: phosphotriesterase: phosphotriesterase: sirohydrochlorin 5'-deoxynucleotidase: glycogen- peptidase L-fucose desuccinylase: astE 2-aminoprop- acetylesterase: glutathione synthetase: fructokinase: alpha-xylosidase: dehydrogenase: 4-fumaryl-acetoacetate demethylase AlkB: alkB SM255186_RS17595 SM255186_RS23530 SM255186_RS21165 SM255186_RS17615 SM255186_RS05920 glucanotransferase: SM255186_RS21165 cobaltochelatase: SM255186_RS12290 cellulase: branching enzyme: E: pepE isomerase: propanoyl-CoA 2-enoate SM255186_RS02565 SM255186_RS15865 bis(sec- SM255186_RS21165 SM255186_RS02025 SM255186_RS05555 sn-glycero-3- a nucleoside 5'- a 2-acyl-sn-glycero- SM255186_RS21280 a dialkyl SM255186_RS10665 SM255186_RS20130 SM255186_RS20810 SM255186_RS21225 a proteinogenic fucI ser succinate formaldehyde a cytosine in DNA a carboxylate sophorosyloxydocosanoate a diribonucleotide diethylthiophosphate chlorferone a fatty acid an rRNA fragment a 5S rRNA ethanol butylsulfanyl) a phenol asp glu phosphoethanolamine acetate monophosphate 3-phosphocholine norophthalmate D-glucopyranose a glucan phosphate 2'-deoxyuridine amino acid phosphate L-serine cobalt-precorrin-2 α-D-xylopyranose a cellodextrin amylopectin keto-D-psicose glu L-arginine phosphinate F6P propanoyltransferase: degradation ammonia-lyase: pduL fumarate acetoacetate III (arginine L-threonine SM255186_RS09570 2-iminopropanoate propanoyl decarboxylase/ degradation II [+ 4 isozymes] a 1-(1-alkenyl) β 6 β 2-aminoprop- a 3-(acyloxy)acyl 1-palmitoyl-2-linoleoyl- a [protein] N-terminal- an N-acetyl- - an N -(1-hydroxy-2- N-acetyl- - chitin dCMP UTP orotidine 5'- dTMP uridine hydrogen phosphate an N-acylphosphatidylethanolamine ethoprophos a uracil in DNA carbonic acid sec A(H2) agmatinase pathway) 2-enoate group of bacterial toxin -sn-glycero-3- phosphatidylcholine formyl-L-methionine D-hexosaminide oxopropyl)-[protein]-L-lysine neuraminate a tRNA ser peroxide L-glutamine arg beta-hexosaminidase: nucleoside triphosphate phosphate thr phospholipase A(1): acyloxyacyl hydrolase: phosphotriesterase: phosphocholine phospholipase A(1): uracil-DNA glycosylase: peptide deformylase: beta-hexosaminidase: protein deglycase N-acetylneuraminate carbonate dehydratase: 5'-deoxynucleotidase: 5'-deoxynucleotidase: uridine kinase: catalase- acetate/propionate degradation I lysoplasmalogenase: SM255186_RS06035 serine--tRNA ligase: pyrophosphohydrolase: orotidine-5'-phosphate SM255186_RS17615 SM255186_RS11835 SM255186_RS21165 SM255186_RS17615 SM255186_RS21830 SM255186_RS06035 YajL: yajL lyase: nanA SM255186_RS00895 SM255186_RS12290 SM255186_RS12290 SM255186_RS11180 peroxidase: family kinase: L-aspartate L-threonine 3- L-asparagine SM255186_RS21045 SM255186_RS13740 N-acetyl-D- SM255186_RS04620 SM255186_RS15005 decarboxylase: pyruvate an N-acyl-2-acyl-1- a 3-hydroxyacyl group 1-linoleoyl-sn-glycero- an apyrimidinic an N-terminal L- an N-acetyl-β- N-acetyl-β-D- katG SM255186_RS10825 dehydrogenase: degradation I a fatty acid a fatty acid ethanol dipropylsulfanylphosphinate sn-glycero-3- palmitate uracil formate an alcohol (R)-lactate a [protein]-L-lysine pyruvate chitin CO H O an L-seryl- degradation I a fatty aldehyde D-hexosamine mannosamine glucosamine 2 2 2'-deoxycytidine UMP SM255186_RS06545 thymidine UMP gln agmatine SM255186_RS20335 lysophosphatidylethanolamine of bacterial toxin phosphocholine 3-phosphocholine site in DNA methionyl-[protein] sec H O A 2-iminopropanoate [tRNA ] UMP 2 [+ 2 isozymes] carbamoyl- L-2-amino-3- phosphate synthase: asp agmatinase: oxobutanoate asn propanoate L-asparaginase 1: SM255186_RS00335 aspartate speB glycine C- SM255186_RS08945 SM255186_RS00340 aminotransferase: acetyltransferase: kbl L-asparaginase 2: [+ 5 isozymes] SM255186_RS04790 putrescine pyruvate SM255186_RS15920 glu oxaloacetate gly asp

a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA ammonium an oligomycin an oligomycin an oligomycin cis-vaccenoyl-CoA cis-vaccenoyl-CoA a xenobiotic a xenobiotic a xenobiotic

RS11510 RS24335 RS05735 RS02430 RS02760 RS09530

a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid ammonium an oligomycin an oligomycin an oligomycin cis-vaccenate cis-vaccenate a xenobiotic a xenobiotic a xenobiotic

This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.