JMIR RESEARCH PROTOCOLS Biondi et al Protocol Remote and Long-Term Self-Monitoring of Electroencephalographic and Noninvasive Measurable Variables at Home in Patients With Epilepsy (EEG@HOME): Protocol for an Observational Study Andrea Biondi1, MSc; Petroula Laiou1, PhD; Elisa Bruno1, MD, PhD; Pedro F Viana1,2, MSc, MD; Martijn Schreuder3, PhD; William Hart4, PhD; Ewan Nurse4,5, PhD; Deb K Pal1, PhD; Mark P Richardson1, BMBCh, PhD 1Institute of Psychiatry, Psychology & Neuroscience, King©s College London, London, United Kingdom 2Faculty of Medicine, University of Lisbon, Hospital de Santa Maria, Lisbon, Portugal 3ANT Neuro UK, Ltd, Stevenage, United Kingdom 4Seer Medical Inc, Melbourne, Australia 5Department of Medicine, St. Vincent's Hospital Melbourne, The University of Melbourne, Melbourne, Australia Corresponding Author: Andrea Biondi, MSc Institute of Psychiatry, Psychology & Neuroscience King©s College London 5 Cutcombe Rd London, SE5 9RT United Kingdom Phone: 44 7753986485 Email:
[email protected] Abstract Background: Epileptic seizures are spontaneous events that severely affect the lives of patients due to their recurrence and unpredictability. The integration of new wearable and mobile technologies to collect electroencephalographic (EEG) and extracerebral signals in a portable system might be the solution to prospectively identify times of seizure occurrence or propensity. The performances of several seizure detection devices have been assessed by validated studies, and patient perspectives on wearables have been explored to better match their needs. Despite this, there is a major gap in the literature on long-term, real-life acceptability and performance of mobile technology essential to managing chronic disorders such as epilepsy. Objective: EEG@HOME is an observational, nonrandomized, noninterventional study that aims to develop a new feasible procedure that allows people with epilepsy to independently, continuously, and safely acquire noninvasive variables at home.