Conference Sponsor Chemical and Biological Microsystems Society (CBMS) cbmsociety.org The Chemical and Biological Microsystems Society (CBMS) is a non profit organization without membership, aiming at the promotion and advancement of science and engineering in the field of chemical and biological microsystems, and to stimulate the exchange of ideas and information between academic, industrial, and government researchers.

MiliLitre Benefactor Emulseo Chemlnnov - 14 avenue Pey Berland Pessac, 33600 FRANCE phone: +33-53-554-1006 [email protected] www.emulseo.com Based in the south west of France, Emulseo has been founded in 2018 by Jean-Christophe Baret, Valérie Taly and Florine Maes. Emulseo develops formulations for microfluidic technology such as the surfactant for droplet-based microfluidics named FluoSurf. Emulseo comes from Jean-Christophe Baret Lab at the Centre de Recherche Paul Pascal in Pessac. Emulseo has thus a strong expertise in microfluidics and aims to help and collaborate with customers in improving and developing new products.

Fluigent 67 Avenue de Fontainebleau Le Kremlin Bicetre, 94270 FRANCE phone: +33-177-01-8268 [email protected] www.fluigent.com Fluigent's broad range of solutions for use in microfluidic technologies and nanofluidics applications offer greater control, automation, precision, and ease of use. If you're seeking to replace high-precision syringe pumps or other conventional instruments, discover the LineUp series, which offer an excellent solution that minimize contamination and ensure full control of flow rates without the need of a computer.

MicroLitre Benefactor Nanoscribe GmbH Hermann-von-Helmholtz-Platz 6 Eggenstein-Leopoldshafen, 76344 GERMANY phone: +49-721-981-980-0 [email protected] www.nanoscribe.com Nanoscribe GmbH develops and provides 3D printers and maskless lithography systems for microfabrication as well as photoresins and process solutions. Today´s market and technology leader for additive microfabrication was founded in 2007 as a spin-off of the Karlsruhe Institute of Technology (KIT, Germany) and has evolved to a medium-sized company with more than 70 employees and subsidiaries in China and the United States. Worldwide, more than 1,500 scientists at top universities and pioneer companies benefit from Nanoscribe´s groundbreaking technology and award-winning solutions for 3D microfabrication. Rapid and dedicated customer support, as well as a worldwide service, are a matter of course for us.

MicroLitre Benefactor, continued RAN Biotechnologies, Inc. 100 Cummings Center, Suite 434J Beverly, MA 01915 USA phone: 1-833-726-2661 [email protected] www.ranbiotechnologies.com RAN Biotechnologies provides reagents and kits for microfluidics, including: Gold standard FluoroSurfactants for water-in- oil emulsions; Customizable Hydrogel Beads: Chip-Free Engineered Droplet Generation kits. All our products combine: w High purity w Reproducibility w Material Customization w Custom Packaging w Experienced Technical and Scientific Support.

Zurich Instruments AG Technoparkstrasse 1 Zurich, 8049 SWITZERLAND phone: +41-44-515-0410 [email protected] www.zhinst.com Zurich Instruments is a manufacturer of test & measurement equipment for advanced research & development applications. The instruments use LabOne® control software that sets a benchmark for efficient instrumentation control and a good user experience. This progressive approach reduces the complexity of laboratory setups, removes sources of problems and supports new measurement strategies that accelerate the progress of research. Zurich Instruments' portfolio comprises lock-in amplifiers, arbitrary waveform generators, impedance analyzers, quantum computing control systems, phase-locked loops and boxcar averagers.

NanoLitre Benefactor NanoLitre Benefactor BEOnChip Ceminem. C/Mariano Esquillor S/N Zaragoza, 50018 SPAIN phone: +34-65-516-1691 [email protected] www.beonchip.com

Biond Solutions B.V. Mekelweg 4 Delft, 2628CD THE NETHERLANDS phone: +31-62-831-3367 [email protected] www.gobiond.com Empowering biological innovation by engineering microchips through nourishing, stimulating and monitoring cells. Bi/ond platform is versatile, as it is qualified for culturing complex 3D tissues (organoids, ex vivo tissue, spheroids, microtissues) as well as for tissue-tissue interface models. Our system consists of six microfluidic chips (inCHIPit) inserted on a six-well plate (comPLATE), designed for a seamless fit. Get in touch with us for a demo.

NanoLitre Benefactor, continued Dolomite Microfluidics 1 Anglian Business Park Royston, SG8 5TW UK phone: +44-1763-252-149 [email protected] www.dolomite-microfluidics.com Dolomite Microfluidics is the industry leader in the design and manufacture of high quality innovative microfluidic products. The company offers a range of microfluidic systems, modules and components - including pumps, chips, connectors, temperature controllers, sensors, accessories and custom-made components - as well as software for analysis or automation. Modularity, ease of use, innovation and scalability are common to all Dolomite products, which are used across a broad range of applications in biology, drug discovery, chemistry, food, cosmetics and academia. Dolomite is a part of the Blacktrace group of companies, a world leader in Productizing Science®, and has offices in the UK, USA, Japan, Hanoi as well as a worldwide network of distributors.

Heidelberg Instruments, Inc. 2539 W. 237th Street, Suite A Torrance, CA 90505 USA phone: 1-310-212-5071 [email protected] www.himt.de Heidelberg Instruments is a world leader in the production of high-precision direct write lithography systems and maskless aligners. Due to their flexibility, these systems are used in research, development and industrial applications for direct writing and photomask production by some of the most prestigious universities and industry leaders in the areas of MEMS, BioMEMS, nano technology, ASICS, TFT, plasma displays, micro optics, and many other related applications.

HiComp Microtech (Suzhou) Co., Ltd. F4, NW-17, Nanopolis Suzhou 99 Jinji Lake Avenue, Suzhou Industrial Park Suzhou, 215000 CHINA phone: +86-512-8781-6000 [email protected] www.hicomp.com The HICOMP MicroTech(Suzhou) Company Limited is an original design manufacturer of high quality components based on cutting-edge micro/nano technologies founded in 2014. We have developed exclusive technologies to produce components with the smallest feature of several micrometers in polymer, glass, ceramic and metal substrates. The target markets include microfluidic and biochips, MEMS and advanced packaging, with a focus on the microfluidics enabled products. Since 2017, we have transformed from a parts supplier to a comprehensive lab-on-a-chip product development and manufacturing partner, providing custom solutions for applications in immunology, clinical chemistry, DNA sequencing and cell manipulation. microfluidic ChipShop GmbH Stockholmer Strasse 20 Jena, THURINGIA 07747 GERMANY phone: +49-36-4134-7050 [email protected] www.microfluidic-chipshop.com microfluidic ChipShop is one of the leading microfluidic service providers and is an established OEM partner in microfluidic cartridge/system development and manufacturing for the diagnostic, pharma and the life science industry. A unique feature of the company is its catalogue with off-the-shelf microfluidic components and systems, allowing a low-cost rapid access to lab- on-a-chip technologies. microfluidic ChipShop offers complete system (cartridge, instrument and assay) development and manufacturing in an ISO 13485 environment.

Micronit Microtechnologies BV Colosseum 15 Enschede, 7521 PV THE NETHERLANDS phone: +31-53-850-6850 [email protected] www.micronit.com NanoLitre Benefactor, continued Newormics 6101 Highland Campus Drive Building 4000, Room 4 2250 Austin, TX 78752 USA [email protected] www.newormics.com Newormics develops high-throughput, high-content, microfluidics-based imaging systems for toxicology screens and disease modeling, using small model organisms such as C. elegans, and tissue organoids. Our flagship product, the vivoChip®, is a microfluidics platform for immobilizing up to ~4,000 C. elegans from 96 individually treated populations within 3 minutes, for high-resolution imaging of cellular and sub-cellular features. vivoScreen® is a fully integrated fluorescence microscopy system for automated high-speed imaging of whole animals in the chip. It provides software to streamline data analysis with a user- friendly GUI for phenotypic scoring, and records dose-dependent effects for toxicity assessment with high statistical power.

OAI 464 South Hillview Drive Milpitas, CA 95035 USA phone: 1-408-232-0600 [email protected] www.oainet.com With over 45 years of experience in the engineering and manufacturing of precision, reliable, and cost-effective lithography solutions, OAI offers a complete series of Mask Aligners, UV Light Sources, and UV Measurement Instrumentation for the Microfluidics, BioTech, MEMS, and Semiconductor Industries. OAI's UV LED Light Source features the same uniformity, intensity and collimation as a standard UV Light Source. This year, OAI introduces for Biotechnology, a Production Mask Aligner with Auto Mask Changer which allows for multiple exposures on the same level and holds up to 100 masks. OAI maintains sales and service worldwide.

Sensific GmbH Kurze Lemppen 1 Ulm, 89075 GERMANY phone: +49-160-9627-0362 [email protected] www.sensific.de Sensific develops innovative measurement technology for research and development. Our first product ODIN is a user-friendly imaging based high-throughput analysis and control system for microfluidics. It analyzes objects fully automatic and controls manipulation devices like sorting gates based on predefined criteria or a machine learning process. It measures more than 30 parameters like size, brightness, granularity, circumference and speed of any passing object like droplets, particles, cells or even complex structures and distinguishes different populations like droplets with certain numbers of encapsulated objects. ODIN works with any optical contrast like bright-field, phase-contrast or fluorescence and integration in most experiments is easy.

Zeon Specialty Materials Inc. 25 Metro Drive, #238 San Jose, CA 95110 USA phone: 1-408-641-7889 www.zeonsmi.com ZEON SPECIALTY MATERIALS (ZSM) is a wholly owned subsidiary of ZEON CORPORATION, a global world leader in the production of specialty elastomers, polymers, and chemicals. ZEON manufactures ZEONEX and ZEONOR Cyclo Olefin Polymer; an ultra-pure, inert, low-fluorescence polymer with glass-like transparency making them ideal choices for optical, diagnostic and life science devices. With a headquarters in San Jose, CA ZSM has positioned itself to not only provide distribution and technical support for COP but also provide microfluidic prototyping services to further aid companies in their development process.

PicoLitre Benefactor AcouSort AB Medicon Village, Building 406 Lund, 22381 SWEDEN phone: +46-707-877-061 [email protected] www.acousort.com AcouSort provides innovative products and solutions for automated preparation of biological samples for researchers and life- science companies. The core technology is acoustofluidics where a combination of microfluidics and sound waves is used to separate blood into its components, to isolate and purify cells and extracellular vesicles and to perform rapid biochemical reactions. With our adaptable technology, sample preparation is tailored to address a wide range of applications - from early biomarker discovery to point of care diagnostics. AcouSort offers stand-alone products for automated sample handling, custom solutions through joint development and off-the-shelf OEM modules for integration in analytical instrument.

BioMedical Microdevices: BioMEMS and Biomedical Nanotechnology 1 New York Plaza New York, NY 10004 USA phone: +31-7865-76100 [email protected] https://www.springer.com/journal/10544

Biomedical Microdevices: BioMEMS and Biomedical Nanotechnology is an interdisciplinary periodical devoted to all aspects of research in the medical diagnostic and therapeutic applications of Micro-Electro-Mechanical Systems (BioMEMS) and nanotechnology for medicine and biology. Subjects of interest include the design, characterization, testing, modeling and clinical validation of microfabricated systems, and their integration on-chip and in larger functional units. The specific interests include systems for neural stimulation and recording, bioseparation technologies, biosensors, and micro/nanotechnologies for cell and tissue research, tissue engineering, cell transplantation, and the controlled release of drugs and biological molecules.

Biophysical Tools GmbH Deutscher Platz 5b Leipzig, 04103 GERMANY phone: +49-341-3929-8131 [email protected] www.biophysical-tools.de Biophysical Tools supports you all around the topic of ultra-precise and fast flow control of fluids in microfluidics / mesofluidics and offers further innovative devices for various biophysical applications. Benefit from our expertise in ultra- precise and -fast flow control of fluids in Microfluidics and Mesofluidics, which is the focus of our leading product groups - a pressure-driven flow control system and multi-channel perfusion system. Our novel products such as tissue stretcher, mobile microscope module and diverse accessories will enhance the usability of your microfluidic setups. Furthermore, we offer numerical simulations of flows, design of microfluidic chips, rapid prototyping and experiment support.

CADworks3D 27 Queen Street, East Suite 1401 Toronto, ON M5C 2M6 CANADA phone: 1-416-368-7266 www.cadworks3d.com CADworks3D was established in 2018 with the intention of providing exceptional user support, cost effective and microfluidic specific 3D printing solutions. By combining groundbreaking 3D printer technology with an in house 3D materials development team, CADworks3D are able to provide 3D solutions to the unique needs of microfluidic researchers, startups and established bio-tech firms. The team at CADworks3D brings together over 20 years of experience in CAD, 3D printing and 3D materials development to empower institutions and research labs with the best technical support.

PicoLitre Benefactor, continued Center of BioModular MultiScale Systems for Precision Medicine (CBM2) University of Kansas Integrated Science Building 1567 Irving Hill Road Lawrence, KS 66045 USA phone: 1-785-864-4160 [email protected] www.cbmm.ku.edu The Center of BioModular Multi-Scale Systems for Precision Medicine (CBM2) is an NIH-funded national Biotechnology Resource Center with expertise in designing, fabricating, and delivering to the biomedical community plastic-based microfluidic and nanofluidic devices that utilize liquid biopsies for disease detection and management. The Center seeks opportunities to disseminate its Core Technologies through Collaborative and Service Projects with clinicians and researchers. CBM2 invites researchers at all levels to participate in its Visiting Scholar Program, to learn more about plastic-based microfluidics/nanofluidics for a variety of applications. With a strong infrastructure of equipment, expertise, and training programs, we are ready to help you.

Elsevier Radarweg 29 Amsterdam, 1043 NX THE NETHERLANDS www.elsevier.com Elsevier, a global leader in information and analytics, helps researchers and healthcare professionals advance science and improve health outcomes for the benefit of society. Growing from our roots in publishing, we have supported the work of our research and health partners for more than 140 years. Elsevier offers knowledge and valuable analytics that help our users make breakthroughs and drive societal progress. Digital solutions such as ScienceDirect, Scopus, SciVal, ClinicalKey and Sherpath support strategic research management, R&D performance, clinical decision support, and health education. Elsevier publishes over 2,500 digitized journals, including The Lancet and Cell; our 39,000 eBook titles; and our iconic reference works, such as Gray's Anatomy. Elsevier is part of RELX, a global provider of information-based analytics and decision tools for professional and business customers.

Elvesys 172 Rue de Charonne Paris, 75011 FRANCE phone: +1-33-188-334-368 [email protected] www.elveflow.com ELVEFLOW is an innovative company with expertise in flow management and microfluidic instrumentation. ELVEFLOW proposes the world's widest brand of microfluidic flow control products. The main mission of the company is to provide state- of-the-art instruments to scientists to help them achieve major advances in their research field. The second mission is to facilitate the access of non-specialists (chemists, biologists) to microfluidics through the development of "plug and play" all- inclusive packs dedicated to specific applications. ELVEFLOW is actively involved in international research projects and the management team has created 9 innovative companies related to microfluidics in the last 8 years.

Hahn-Schickard Georges-Köhler-Allee 103 Freiburg, 79110 GERMANY phone: +49 761 203-73200 [email protected] www.Hahn-Schickard.de Lab-on-a-chip - from the initial idea to the final product: Hahn-Schickard is your one-stop-shop, offering the whole R+D workflow for development, test and pilot production. At its site in Freiburg (Germany), the focus is on customized solutions for research and molecular point-of-need diagnostics. The R+D service provider solves your challenges in miniaturized liquid handling, assay development and instrumentation. With a pilot line, Hahn-Schickard can deliver Lab-on-a-chip cartridges for validation and market entry supporting the product visions of its customers even more effectively.

PicoLitre Benefactor, continued Hexano PO Box 29029, Moncton North Moncton, E1G1A0 CANADA phone: 1-800-695-0021 [email protected] www.hexano.net Hexano brings your microfluidic chips out of the lab and commercializes it. We focus on mass manufacturing through plastic injection. We also offer prototyping services so you can migrate from your PDMS chips to thermoplastics. Choose Hexano as your manufacturing partner and we'll handle the rest.

IamFluidics BV Enschede, 7522 THE NETHERLANDS phone: +31-53-234-0044 [email protected] www.iamfluidics.com

Icomes Lab Co., Ltd. 2-4-23, Kitaiioka Morioka, 020-0857 JAPAN phone: +81-19-601-8157 [email protected] www.icomes.co.jp/en Micro Actuator × Liquid Handling. Unique liquid handling device and Made in Japan

Jobst Technologies GmbH Engesserstrasse 4b Freiburg, 79108 GERMANY phone: +49-761-6129-5473 [email protected] www.jobst-technologies.com Jobst Technologies GmbH is offering its core competencies in the overlap between microsystems technology, (bio)electrochemical analytics and microfluidics to its customers. The company is unrivaled competence leader in bioanalytical applications with OEM products in clinical routine continuous monitoring and biotechnology as well as micro/nano fluidic systems. B2B contract development together with EU research projects provides permanent extension of the company's technology and product portfolio. "Rational technology integration aiming at bio-micro convergence" is a slogan created by Gerhard. Jobst, CEO of Jobst Technologies. Adding a strong dedication to customer satisfaction this leads to real world systems of outstanding reliability and stability.

LabSmith 5981 Graham Court Livermore, CA 94550 USA phone: 1-925-292-5164 [email protected] www.labsmith.com LabSmith, designs and manufactures laboratory tools for microfluidics and microbiology. LabSmith products control all aspects of experimentation, including microfluidic fluid routing and automation components, high voltage supplies for electrophoresis and gel electrophoresis, and inverted fluorescence video microscopes for capturing and quantifying key events. For research and OEM applications, LabSmith products and software work together to take the headaches out of experimental setup, so you can focus on science.

µFluidic - Nehir Biyoteknoloji Ltd. ODTU-OSTIM Teknokent, 1308 Cd, No-6-2B8 Yenimahalle, 06374 TURKEY phone: +90-312-386-0423 [email protected] www.uFluidic.com PicoLitre Benefactor, continued PreciGenome 2176 Ringwood Avenue San Jose, CA 95131 USA phone: 1-408-708-4602 [email protected] www.precigenome.com

PreciGenome's innovative microfluidic pressure/flow controller and high speed imaging system are the most convenient tools for a variety of applications and system integration. Combining them with valves, tubing and fitting, reservoir kits, and microfluidic chips, we successfully demonstrated perfusion systems (multiple reagent dispensing or media recirculating perfusion), droplet generation systems, single cell encapsulation systems, nanoparticle synthesis systems, and organ-on-a-chip systems, etc. PreciGenome also offers custom design and OEM solutions for customers who need microfluidic instrument development and production.

Research, a Science Partner Journal 1200 New York Avenue, NW Washington, DC 20005 USA phone: 202-326-6417 spj.sciencemag.org/journals/research/ The Science Partner Journal Research is and online Open Access journal distributed by the American Association for the Advancement of Science (AAAS) in association with Science and Technology Review Publishing House, the publishing house under the leadership of China Association for Science and Technology (CAST). Research provides an international platform for academic exchange, collaboration and technological advancements. The journal publishes fundamental research in the life and physical sciences as well as important findings or issues in engineering and applied science.

Science Advances/AAAS 1200 New York Avenue, NW Washington, DC 20005 USA phone: 1-202-326-6417 [email protected] advances.sciencemag.org Science Advances is the American Association for the Advancement of Science's (AAAS) gold open access journal, publishing research papers and reviews in all areas of science. Its mission is to provide fair, fast, and expert peer review and a vetted selection of research, freely available to all readers. Science Advances extends the capacity of Science magazine to identify and promote significant advances and developments across a wide range of areas. The journal plays a critical role in building and sustaining AAAS's mission as a global participant and advocate for the communication and use of science to benefit humankind.

Springer Nature 1 New York Plaza, Suite 4600 New York, NY 10004 USA phone: 1-212-460-1500 [email protected] www.springer.com

STRATEC Consumables GmbH Sonystrasse 20 Anif, Salzburg, 5081 AUSTRIA phone: +43-6246-21250 [email protected] www.stratec.com/solutions/consumables STRATEC Consumables GmbH is a leading OEM supplier of smart polymer-based consumables to the in-vitro diagnostics, life sciences and medical technology industries. The company has an unique combination of skills and technologies including nano- and microstructuring, coating technologies, polymer sciences, and automated assembly. With its certified production facility and a global logistics network, STRATEC Consumables covers the entire value chain, from development via production and quality assurance through to logistics. The company meets all regulatory requirements in the relevant target markets. Its customers include global players in highly regulated markets as well as innovative start-ups. PicoLitre Benefactor, continued Vision Research 100 Dey Road Wayne, NJ 07470 USA phone: 1-973-696-4500 [email protected] www.phantomhighspeed.com

Media Benefactor Microtech Ventures, Inc. 550 Merrill Street, Suite 240 Birmingham, MI 48009 USA [email protected] microtechventures.com Microtech Ventures is focused on strategic venture capital, angel investing, and M&A advisory services. Our mission is to accelerate the development of MEMS, sensors, and microtechnologies for the advancement of human civilization and the improvement of quality of life. Our deep industry knowledge and extensive network, combined with practical hands-on strategy experience, enables us to quickly identify the connections that result in multiple opportunities to maximize ownership value, and ensure successful outcomes. separations MDPI Academic Open Access Publishing Since 1996 St. Alban-Anlage 66 Basel, 4052 SWITZERLAND phone: +41-61-683-7734 [email protected] www.mdpi.com/journal/separations

Awards Analytical Chemistry Young Innovator Award This award, sponsored by the Journal of Analytical Chemistry and Chemical and Biological Microsystems Society (CBMS), recognizes the contributions of an individual who has demonstrated exceptional technical advancement and innovation in the field of micro- or nanofluidics in his or her early career.

Lab on a Chip and Dolomite Pioneers in Miniaturization Prize An award given for young-to-mid-career scientists, the prize recognizes outstanding contributions to the understanding and development of miniaturized systems. Sponsored by Lab on a Chip, Dolomite, and Chemical and Biological Microsystems Society (CBMS).

Awards, continued NIST and Lab on a Chip Art in Science Award To draw attention to the aesthetic value in scientific illustrations while still conveying scientific merit, the MicroTAS Conference features an award titled, “Under the Looking Glass: Art from the World of Small Science” sponsored by NIST and Lab on a Chip. Applications are encouraged from any person attending the MicroTAS Conference and the winner will be selected by a panel of senior scientists in the field of MicroTAS.

Lab on a Chip Widmer Poster Award The Widmer Poster Award Competition sponsored by the Lab on a Chip is an award given to recognize excellence amongst the annual MicroTAS Conference poster presenters. A review committee will select the overall best-presented poster from the poster session and all presented posters will be reviewed for this honor.

CHEMINAS Young Researcher Poster Awards The Young Researcher Poster Award Competition sponsored by The Society for Chemistry and Micro-Nano Systems (CHEMINAS) to recognize excellence among its participants. A select group of poster judges will select, on a daily basis, the best presented posters from the poster session.

IMT Masken und Teilungen AG Microfluidics on Glass Poster Award To be relevant to the spirit and intent of this Microfluidics on Glass Award, the advancement considered must address at least one of the following: • Use glass as a substrate material for a nano/microfluidic device where the unique optical, electrical, or surface properties of glass provide a profound advantage; • Demonstrate novel biosensing capabilities; • Exhibit hybridisation of glass with other materials (composites); • Establish design for manufacturability with materials and processes that have the potential to be scaled up through transfer to industry

MDPI Micromachines & the Chemical Biological Microsystems Society (CBMS) Flash Presentation Award Sponsors The Flash Presentation Award sponsored by MDPI Micromachines & the Chemical Biological Microsystems Society (CBMS) to recognize excellent poster presenters with flash presentations to advertise their posters in a dynamic and creative manner. Attributes of excellence include being original and highly informative; other attributes including being visually appealing and using humor may be appreciated as well.

Awards, continued Sensors (MDPI) Outstanding Sensors and Actuators, Detection Technologies Poster Award The Outstanding Sensors and Actuators, Detection Technologies Poster Award Competition sponsored by Sensors (MDPI), is to recognize excellence among its participants.

Biomicrofluidics - Best Paper Award The Best Paper Award sponsored by Biomicrofluidics to recognize the three best papers submitted to the MicroTAS Conference.

Workshops - Saturday, October 3

Workshop 1 09:00 - 10:00 PLUG AND PLAY: FLUIDS DELIVERY AND SYSTEM INTEGRATION Nicolas Verplanck1, Leanna Levine2, Masumi Yamada3, and Edmond Young4, 1Atomic Energy and Alternative Energies Commission - CEA, FRANCE, 2ALine, Inc, USA, 3Chiba University, JAPAN, and 4University of Toronto, CANADA

Workshop 4 10:00 - 11:00 ADVANCED MICROSCOPY TECHNIQUES FOR CELL IMAGING IN 3D Petra Paiè1, Billy Huang2, and Vincent Haguet3 1Istituto di Fotonica e Nanotecnologie, CNR, ITALY, 2Nebulum Technologies, TAIWAN and 3CEA, Grenoble, FRANCE

Workshop 6 08:00 - 09:00 SURFACE FUNCTIONALIZATION IN MICROFLUIDICS Sung Gap Im1 and Ying-Chih Chang2,3 1Korea Advanced Institute of Science and Technology (KAIST), KOREA, 2Academia Sinica, TAIWAN, and 3Stanford University, USA

Workshop 7 08:00 - 09:00 SMALL-SCALE BIOREACTORS Krist V. Gernaey1, Wim De Malsche2, Pei-Chen Chiang3, and Katrin Rosenthal4 1Technical University of Denmark, DENMARK, 2Vrije Universiteit Brussel, BELGIUM, 3Corning Research Center, TAIWAN, and 4Technical University Dortmund, GERMANY

Workshop 8 09:00 - 10:00 BIO/3D-PRINTING Shrike Zhang1, Mei He2, Oni Basu3, and Hongkai Wu4 1Harvard Medical School, USA, 2University of Florida, USA, 3University of Chicago, USA, and 4Hong Kong University of Science and Technology, HONG KONG

Workshop 9 10:00 - 11:00 LIQUID BIOPSY - LATEST DEVELOPMENT IN THE CTC, EXOSOME AND FREE-FLOATING DNA FOR DIAGNOSIS Sunitha Nagrath1, Valérie Taly2, Chih-Chen Chen3, Leon Terstappen4, Fikri Abali4, and Afroditi Nanou4 1University of Michigan, USA, 2Université de Paris, FRANCE, 3National Tsing Hua University, TAIWAN, and 4University of Twente, THE NETHERLANDS

Workshop 12 11:00 - 12:00 POINT OF CARE FOR GLOBAL HEALTH Fernando Benito Lopez1, Yuksel Temiz2, Jacqueline Linnes3, and Konstantinos Mitsakakis4 1Universidad del País Vasco, SPAIN, 2IBM, SWITZERLAND, 3Purdue University, USA, 4University of Freiburg - IMTEK, GERMANY

Workshops - Sunday, October 4

Workshop 2 08:00 – 09:00 SENSOR INTEGRATION IN MICROFLUIDICS Federico Paratore1, Federica Caselli2 and Chii-Wann Lin3 1IBM, SWITZERLAND, 2University of Rome Tor Vergata, ITALY, and 3National Taiwan University, TAIWAN

Workshop 3 09:00 – 10:00 OPEN SPACE MICROFLUIDIC Jean Berthier1, Thomas Gervais2, and Mohammad Qasaimeh3 1University of Washington, USA, 2Polytechnique Montréal, Canada, and 3New York University Abu Dhabi, UAE

Workshop 5 11:00 – 12:00 FLOW MODELING AND VISUALIZATION IN MICROFLUIDICS Henrik Bruus1, Wei-Hsin Tien2, Rune Barnkob3, and Yuki Minamoto4 1Technical University of Denmark, DENMARK, 2National Taiwan University of Science and Technology, TAIWAN, 3Technical University of Munich, GERMANY, and 4Flowsquare+/Tokyo Institute of Technology, JAPAN

Workshop 10 10:30 – 11:30 ORGAN ON CHIP AND MICROFLUIDIC-BASED TISSUE ENGINEERING Stephanie Descroix1, Deok-Ho Kim2, Rebecca Rose Pompano3, and Anna Herland4 1Institut Curie - CNRS, FRANCE, 2Johns Hopkins University School of Medicine, USA, 3University of Virginia, USA, and 4KTH Royal Institute of Technology, SWEDEN

Workshop 11 10:00 – 11:00 DROPLET MICROFLUIDICS Yegan Erdem1, Håkan Jönsson2, and Charles Baroud3 1Bilkent University, TURKEY, 2KTH Royal Institute of Technology, SWEDEN, and 3Institut Pasteur, FRANCE

Day 1 - Monday, October 5

Opening Remarks – Welcome Address 08:00 CBMS President Nicole Pamme, University of Hull, UK

College of Engineering - Georgia Institute of Technology, USA Steve McLaughlin, Provost and Executive Vice President for Academic Affairs

University of Twente, THE NETHERLANDS Victor van der Chijs, President Executive Board (CVB)

MicroTAS 2020 Conference Chairs Séverine Le Gac, University of Twente, THE NETHERLANDS Hang Lu, Georgia Institute of Technology, USA

Plenary Speaker Presentation I Session Chairs Je-Kyun Park, Korea Advanced Institute of Science and Technology (KAIST), KOREA Manabu Tokeshi, Hokkaido University, JAPAN 08:25 - 09:25 MP-01 ON-CHIP ROBOTICS: EMERGING FUNCTIONS IN MICROFLUIDIC ENVIRONMENT WITH INTEGRATION OF SENSORS & ACTUATORS Fumihito Arai University of Tokyo, JAPAN

09:25 - 09:30 Transition Break

Poster Session M1 09:30 - 10:30 Presentations are listed by topic category with their assigned number starting on page 16.

Coffee Break (offline) or join the Daily Quiz Featuring Fluigent 10:30 - 10:45 Join us for a quick quiz hosted by Fluigent. We will use Kahoot! for this quiz, so please install Kahoot! on your smartphone or head over to www.kahoot.it in your web browser. Further instructions available upon joining. Winner will be selected to participate in “Who Wants to be a Millionthaire?” on Friday.

Panel Discussion I Moderators: Audrey Bowden, Vanderbilt University, USA Wouter van der Wijngaart, KTH Royal Institute of Technology, SWEDEN 10:45 - 11:35 WOMEN IN ACADEMIA Sabeth Verpoorte1, Karen Cheung2, and Lingling Shui3 1University of Groningen, THE NETHERLANDS, 2University of British Columbia, CANADA, and 3South China Normal University, CHINA

Panel Discussion II Moderators: Abraham P. Lee, University of California, Irvine, USA Bastien Venzac, University of Twente, THE NETHERLANDS 10:45 - 11:35 ETHICS IN SCIENCE Claire Ribrault1, Adam Marcus2, Philippa Ross3, and Jun Fudano4 1Ateliers des Jours à Venir, FRANCE, 2Retraction Watch, USA, 3Royal Society of Chemistry, UK, and 4Waseda University, JAPAN

Industrial Stage 1 Session Chairs Sally Peyman, University of Leeds, UK Shoji Takeuchi, University of Tokyo, JAPAN 10:45 - 11:10 1a - Zurich Instruments AG FAST IMPEDANCE SPECTROSCOPY FOR CHARACTERIZATION AND COUNTING

11:10 - 11:35 1b - microfluidic ChipShop GmbH WHY ISN’T ELON MUSK DOING MICROFLUIDICS?

Industrial Stage 2 Session Chairs Daniel Citterio, Keio University, JAPAN Mei He, University of Florida, USA 10:45 - 11:10 2a – Newormics LLC VIVOCHIP: HIGH-CONTENT ANALYSIS OF DISEASE MODELS AND TOXICOLOGY STUDIES USING C. ELEGANS

11:10 - 11:35 2b – Biond Solutions B.V. NOURISHING, STIMULATING AND MONITORING CELLS WITH MICROELECTRONICS

11:35 - 11:40 Transition Break

Poster Session M2 11:40 - 12:40 Presentations are listed by topic category with their assigned number starting on page 16.

12:40 Adjourn for the Day

Day 2 - Tuesday, October 6

Plenary Speaker Presentation II Session Chairs Nicole Pamme, University of Hull, UK Wouter van der Wijngaart, KTH Royal Institute of Technology, SWEDEN 08:00 - 09:00 TP-02 COVID-19: CHANGING DIRECTIONS OF A PERFECT STORM Herman Goossens University of Antwerp, BELGIUM

09:00 - 09:05 Transition Break

09:05 - 09:35 Speaker Corner with Herman Goossens

Poster Session T3 09:05 - 10:05 Presentations are listed by topic category with their assigned number starting on page 16.

Coffee Break (offline) or join one of the Daily Quizzes featuring RAN Biotechnologies and Zurich Instruments 10:05 - 10:20 Join us for a quick quiz hosted by RAN Biotechnologies and Zurich Instruments. We will use Kahoot! for this quiz, so please install Kahoot! on your smartphone or head over to www.kahoot.it in your web browser. Further instructions available upon joining. Winner will be selected to participate in “Who Wants to be a Millionthaire?” on Friday.

Plenary Speaker Presentation III Session Chairs Don DeVoe, University of Maryland, College Park, USA Joel Voldman, Massachusetts Institute of Technology (MIT), USA 10:20 - 11:20 TP-03 CHEMICAL SYNTHESIS ENABLED BY MICROFLUIDICS, AUTOMATION, AND MACHINE LEARNING Klavs F. Jensen Massachusetts Institute of Technology, USA

11:20 - 11:25 Transition Break

11:25 - 11:55 Speaker Corner with Klavs F. Jensen

Poster Session T4 11:25 - 12:25 Presentations are listed by topic category with their assigned number starting on page 16.

12:25 - 12:30 Transition Break Shark Tank Moderators Luc Bousse, Kryptos Biotechnologies, USA Michelle Khine, University of California, Irvine, USA Sumita Pennathur, University of California, Santa Barbara, USA 12:30 - 13:30 Panel of Judges Don Arnold, Veristad, USA Holger Becker, microfluidic ChipShop, GERMANY David Cohen, Marker AG, USA Yolanda Fintschenko, FounderTraction, USA JD Harriman, Foundation Law Group, USA Dirk Heckel, DH Diagnostics LLC, a Danaher Company, USA Carl Meinhart, University of California, Santa Barbara, USA Tomoko Minagawa, Global Brain Corporation, JAPAN Josh Molho, Milo at ProteinSample, USA Akhil Saklecha, Cleveland Clinic Ventures, USA Erez Podoly, MightyGate, USA

13:30 Adjourn for the Day

Day 3 - Wednesday, October 7

Keynote Presentation I Session Chairs Kazuma Mawatari, University of Tokyo, JAPAN Fan-Gang Tseng, National Tsing Hua University, TAIWAN 08:00 - 08:30 WK-01 LIQUID MARBLE BASED DIGITAL MICROFLUIDICS: FUNDAMENTAL PHYSICS AND APPLICATIONS Nam-Trung Nguyen, Chin Hong Ooi, Raja Vadivelu, Kamalalayam Rajan Sreejith, Jing Jin, Nhat-Khuong Nguyen, and Pradip Singha Griffith University, AUSTRALIA

Keynote Presentation II Session Chairs Stephanie Descroix, Institut Curie CNRS, FRANCE Jacqueline Linnes, Purdue University, USA 08:00 - 08:30 WK-02 ENGINEERING AND MEASURING SYSTEMIC MULTI-ORGAN INTERACTIONS FOR TRANSLATIONAL APPLICATIONS Lor Huai Chong2, Hsih Yin Tan2, Louis Ong1,2, Christopher Tostado2, and Yi-Chin Toh1 1Queensland University of Technology, AUSTRALIA and 2National University of Singapore, SINGAPORE

Keynote Presentation III Session Chairs Ian Papautsky, University of Illinois, Chicago, USA Hongkai Wu, Hong Kong University of Science and Technology, HONG KONG 08:00 - 08:30 WK-03 INKJET-BASED HIGH THROUGHPUT SINGLE CELL DISPENSING Karen C. Cheung University of British Columbia, CANADA

Keynote Presentation IV Session Chairs Hugh Fan, University of Florida, USA Chang-Soo Lee, Chungnam National University, KOREA 08:00 - 08:30 WK-04 MICROFLUIDICS FOR LIQUID BIOPSY Chao Liu, Fei Tian, and Jiashu Sun National Center for Nanoscience and Technology, CHINA

08:30 - 08:35 Transition Break

Speaker Corners 08:35 – 09:05 Nam-Trung Nguyen, Yi-Chin Toh, Karen C. Cheung, and Jiashu Sun

Poster Session W5 08:35 - 09:35 Presentations are listed by topic category with their assigned number starting on page 16.

09:35 - 09:40 Transition Break

Panel Discussion III Moderators: Yi Chin Toh, Queensland University of Technology, AUSTRALIA Wouter van der Wijngaart, KTH Royal Institute of Technology, SWEDEN 09:40 - 10:30 ADVICE FOR EARLY CAREERS IN ACADEMIA Albert van den Berg1, Maria Tenje2, Joel Voldman3, Jacqueline Linnes4, Yoon-Kyoung Cho5, and Ya-Yu Chiang6 1University of Twente, THE NETHERLANDS, 2Uppsala University, SWEDEN, 3Massachusetts Institute of Technology, USA, 4Purdue University, USA, 5Ulsan National Institute of Science and Technology (UNIST), KOREA, and 6National Chung-Hsing University, TAIWAN

Panel Discussion IV Moderators: Aaron Wheeler, University of Toronto, CANADA Monica Brivio, Micronit Microtechnologies, THE NETHERLANDS 09:40 - 10:30 WOMEN IN INDUSTRY Leanna Levine1, Alissa Fitzgerald2, Claudia Gaertner3, France Hamber4, Mika Mizunuma5, and Hong Ya Ying6 1A-Line, USA, 2A.M. Fitzgerald & Associates, USA, 3microfluidic ChipShop, GERMANY, 4Fluigent, FRANCE, 5CRAIF, JAPAN, and 6Shenzhen Shineway Technology Corp., HONG KONG

Industrial Stage 3 Session Chairs Joan Bienvenue, University of Virginia, USA Kevin Nichols, Global Health Labs, USA 09:40 - 10:05 3a – Springer Nature BOOK PUBLISHING @ SPRINGER NATURE

10:05 - 10:30 3b – Fluigent in Partnership with BEOnChip Fluigent/ BEOnChip: A STRATEGIC PARTNERSHIP TO BETTER ADDRESS THE NEEDS OF THE MULTIDISCIPLINARY FIELD OF ORGAN ON CHIP

Industrial Stage 4 Session Chairs Cullen Buie, Massachusetts Institute of Technology, USA Rebecca Pompano, University of Virginia, USA 09:40 - 10:05 4a – HiComp Microtech (Suzhou) Co., Ltd. CHALLENGES AND SOLUTIONS FOR NEW DIAGNOSTIC CONSUMABLE MANUFACTURING

10:05 - 10:30 4b – Heidelberg Instruments CHALLENGES AND SOLUTIONS FOR NEW DIAGNOSTIC CONSUMABLE MANUFACTURING

Coffee Break (offline) or join the Daily Quiz featuring Emulseo 10:30 - 10:45 Join us for a quick quiz hosted by Emulseo. We will use Kahoot! for this quiz, so please install Kahoot! on your smartphone or head over to www.kahoot.it in your web browser. Further instructions available upon joining. Winner will be selected to participate in “Who Wants to be a Millionthaire?” on Friday.

Poster Session W6 10:45 - 11:45 Presentations are listed by topic category with their assigned number starting on page 16.

11:45 - 11:50 Transition Break

Plenary Speaker Presentation IV Session Chairs Hang Lu, Georgia Institute of Technology, USA Jonas Tegenfeldt, Lund University, SWEDEN 11:50 - 12:50 WP-04 SKIN-INSPIRED MATERIALS, SENSORS AND APPLICATIONS Zhenan Bao Stanford University, USA

12:50 - 12:55 Transition Break

12:55 - 13:25 Speaker Corner with Zhenan Bao

13:25 Adjourn for the Day

Day 4 - Thursday, October 8

Plenary Speaker Presentation V Session Chairs Yoon-Kyoung Cho, Ulsan National Institute of Science and Technology (UNIST), KOREA Amy Herr, University of California, Berkeley, USA 08:00 - 09:00 ThP-05 BIOCOMPATIBLE INTERFACES OF NANOSTRUCTURED POLYMER FOR ADVANCED MEDICAL AND HEALTHCARE DEVICES Madoka Takai University of Tokyo, JAPAN

09:00 - 09:05 Transition Break

09:05 – 09:35 Speaker Corner with Madoka Takai

Poster Session Th7 09:05 - 10:05 Presentations are listed by topic category with their assigned number starting on page 16.

Coffee Break (offline) or join the Daily Quiz featuring Nanoscribe GmbH 10:05 - 10:20 Join us for a quick quiz hosted by Nanoscribe GmbH. We will use Kahoot! for this quiz, so please install Kahoot! on your smartphone or head over to www.kahoot.it in your web browser. Further instructions available upon joining. Winner will be selected to participate in “Who Wants to be a Millionthaire?” on Friday.

Panel Discussion V Moderators: Michinao Hashimoto, Singapore University of Technology and Design, SINGAPORE Agnieszka Zuchowska, University of Twente, THE NETHERLANDS 10:20 - 11:10 PARENTING IN SCIENCE AND WORK-LIFE BALANCE Agnes Tixier-Mita1, Yoshio Mita1, Yong Zeng2, Mei He2, Jonas Tegenfeldt3, and Christelle Prinz3 1University of Tokyo, JAPAN, 2University of Florida, USA, and 3Lund University, SWEDEN

Panel Discussion VI Moderators: Yi Chin Toh, Queensland University of Technology, AUSTRALIA Daniel Citterio, Keio University, JAPAN 10:20 - 11:10 STUDENTS AND POSTDOCS STUDYING ABROAD Petra Dittrich1, Gaspard Pardon2, Dino Di Carlo3, Darius Rackus1 Anderson Shum4, and Christopher Tostado5 1ETH Zürich, Basel, SWITZERLAND, 2Stanford University, USA, 3University of California, Los Angeles, USA, 4Hong Kong University, HONG KONG, and 5Genome Institute of Singapore, SINGAPORE

Industrial Stage 5 Session Chairs Ya-Yu Chiang, National Chung Hsing University, TAIWAN John Oakey, University of Wyoming, USA 10:20 - 10:45 5a – Jobst Technologies GmbH NANO/ MICRO FLOW SYSTEMS, AND BIOSENSORS

10:45 – 11:10 5b – PreciGenome LLC A TOOL BOX FOR MICROFLUIDIC SYSTEM INTEGRATION AND ITS APPLICATIONS

Industrial Stage 6 Session Chairs Axel Guenther, University of Toronto, CANADA Tiina Sikanen, University of Helsinki, FINLAND 10:20 - 10:45 6a – Vision Research, AMETEK HIGH-SPEED IMAGING SOLUTIONS FOR IMAGE CYTOMETRY

10:45 - 11:10 6b – STRATEC Consumables GmbH COLLABORATION BY DESIGN – HOW TO INTEGRATE PARTNERS IN THE DEVELOPMENT AND MANUAFCTURING OF NEXT GENERATION DIAGNOSTICS

11:10 - 11:15 Transition Break

Poster Session Th8 11:15 - 12:15 Presentations are listed by topic category with their assigned number starting on page 16.

12:15 - 12:20 Transition Break

Keynote Presentation V Session Chairs Stephen Jacobson, Indiana University, USA Marcel Utz, University of Southampton, UK 12:20 - 12:50 ThK-05 EMERGING WATER TREATMENT TECHNOLOGIES Matthew E. Suss, Shada Abu Khalla, Imri Atlas, Eric Guyes, and Amit Shocron Technion - Israel Institute of Technology, ISRAEL

Keynote Presentation VI Session Chairs Katherine Elvira, University of Victoria, CANADA Han Wei Hou, Nanyang Technological University, SINGAPORE 12:20 - 12:50 ThK-06 NANOSTRUCTURES FOR PROBING AND TRANSFECTING LIVING CELLS Christelle N. Prinz Lund University, SWEDEN

Keynote Presentation VII Session Chairs Lourdes Basabe, University of the Basque Country and IKERBASQUE, SPAIN Charles Henry, Colorado State University, USA 12:20 - 12:50 ThK-07 EXPANDING THE (i)SIMPLE MICROFLUIDIC TOOLBOX TOWARDS ADVANCED DIAGNOSTICS AND THERAPEUTICS Dries Vloemans, Lorenz Van Hileghem, Henry Ordutowski, Dragana Spasic, Francesco Dal Dosso, and Jeroen Lammertyn KU Leuven, BELGIUM

Keynote Presentation VIII Session Chairs Govind Kaigala, IBM Research, Zurich, SWITZERLAND Darwin Reyes, National Institute of Standards and Technology (NIST), USA 12:20 - 12:50 ThK-08 SQUEEZING DNA IN NANOCHANNELS Kevin D. Dorfman University of Minnesota, USA

12:50 - 12:55 Transition Break

Speaker Corners 12:55 – 13:25 Matthew E. Suss, Christelle N. Prinz, Jeroen Lammertyn, and Kevin D. Dorfman

13:25 Adjourn for the Day

Day 5 - Friday, October 9

Plenary Speaker Presentation VI Session Chairs Petra Dittrich, ETH Zürich, Basel, SWITZERLAND Séverine Le Gac, University of Twente, THE NETHERLANDS 08:00 - 09:00 FP-06 WATER-REPELLENT MATERIALS: A FEW TRICKS WE LEARNT FROM NATURE, AND BEYOND David Quéré ESPCI-Paris, PSL Research University, FRANCE

09:00 - 09:05 Transition

09:05 – 09:35 Speaker Corner with David Quéré

Analytical Chemistry Young Innovator Award and Presentation 09:05 - 09:25 BUILDING SYNTHETIC HUMAN EMBRYO-LIKE STRUCTURES Jianping Fu University of Michigan, Ann Arbor, USA

Lab on a Chip and Dolomite Pioneers of Miniaturization Lectureship Award and Presentation 09:25 - 09:45 CLINICAL TRANSLATION OF MICROFLUIDIC SYSTEMS AND LESSONS LEARNED FROM THE COVID-19 PANDEMIC Wilbur A. Lam1,2 1Emory University, USA and 2Georgia Technical University, USA

09:45 - 09:50 Transition

Who Wants to be a Millionthaire? Moderator Darius Rackus, ETH Zürich, Basel, SWITZERLAND 09:50 - 10:50

Join us for “Who Wants to be a Millionthaire?”, the very first MicroTAS gameshow! Twelve contestants will compete in rounds of trivia, games of skill, and silly activities all for a chance to win one free registration to MicroTAS 2021 in Palm Springs. Contestants will be selected through participation in the daily quizzes. Two lucky attendees will also have the chance to enter. There will be lots of audience participation, so join in for a little bit of fun at the end of this week!

10:50 - 11:05 Coffee Break (offline)

Award Ceremony Session Chairs Stephanie Descroix, Institut Curie CNRS, FRANCE Thomas Gervais, Polytechnique Montréal, CANADA Je-Kyun Park, Korea Advanced Institute of Science and Technology (KAIST), KOREA 11:05 – 12:15 CHEMINAS - Young Researcher Poster Awards Lab on a Chip - Widmer Poster Award IMT Masken und Teilungen AG - Microfluidics on Glass Poster Award Sensors (MDPI) - Outstanding Sensors and Actuators, Detection Technologies Poster Award National Institute of Standards and Technology (NIST) and Lab on a Chip - Art in Science Award Micromachines (MDPI) and CBMS - Flash Poster Presentation Awards Biomicrofluidics (AIP) - Best Paper Awards

Closing Remarks 12:15 MicroTAS 2020 Conference Chairs Séverine Le Gac, University of Twente, THE NETHERLANDS Hang Lu, Georgia Institute of Technology, USA

12:35 Conference Adjourns POSTER PRESENTATIONS

M1 – Monday, October 5 09:30 - 10:30 M2 – Monday, October 5 11:40 - 12:40 T3 – Tuesday, October 6 09:05 - 10:05 T4 – Tuesday, October 6 11:25 - 12:25 W5 – Wednesday, October 7 08:35 - 09:35 W6 – Wednesday, October 7 10:45 - 11:45 Th7 – Thursday, October 8 09:05 - 10:05 Th8 – Thursday, October 8 11:15 - 12:15

Classification Chart (last character of poster number)

a Fundamentals in Microfluidics and Nanofluidics b Micro- and Nanoengineering c Sensors and Detection Technologies d Integrated Microfluidic Platforms e Cells, Organisms and Organs on a Chip f Diagnostics, Drug Testing & Personalized Medicine g Other Applications of Microfluidics

a - Fundamentals in Microfluidics and Nanofluidics Electrokinetic Phenomena M2-201.a AN ELECTROKINETIC-BASED LARGE VOLUME CONCENTRATOR FOR ULTRA-LOW ABUNDANT TARGET DETECTION Hyukjin J. Kwon, Bryan Lenneman, Timothy Lu, Kyungyong Choi, and Jongyoon Han Massachusetts Institute of Technology, USA

T3-301.a CHARACTERIZING SINGLE SINONASAL SQUAMOUS CELL CARCINOMA USING DI- ELECTROPHORESIS AND ELECTROROTATION Thao N.P. Mai1, Sakina Bensalem1, Bénédicte Thiebot2, Philippe Manivet3, Juan Pelta2, and Bruno Le Pioufle1 1Ecole Normale Superieure de Paris-Saclay, FRANCE, 2Université Paris-Saclay, Université Evry, FRANCE, and 3University of Paris 10, FRANCE

T4-401.a CONTROLLING AC-ELECTROOSMOTIC VORTEX FLOWS BY SHAPING THE CHANNEL CROSS SECTION Christina Tiflidis1,2, Eiko Westerbeek1,2, Koen F.A. Jorissen2, Wouter Olthuis2, Jan Eijkel2, and Wim De Malsche1 1Vrije Universiteit Brussel, BELGIUM and 2University of Twente, THE NETHERLANDS

W5-501.a DIELECTROPHORETIC EQUILIBRIUM OF COMPLEX PARTICLES Tom Elkeles1, Pablo Garcia-Sanchez2, Wu Yue1, Antonio Ramos2, and Gilad Yossifon1 1Technion – Israel Institute of Technology, ISRAEL and 2Universidad de Sevilla, SPAIN

W6-601.a ELECTROKINETIC WALL EFFECT MECHANISMS AND APPLICATIONS Jason P. Beech, Bao Dang Ho, Oskar Ström, and Jonas O. Tegenfeldt Lund University, SWEDEN

Th7-701.a N-DEP ENHANCED LATERAL DISPLACEMENT IN DLD DEVICE TO FOR HIGH EFFICIENT CELL SORTING Chia-Hsin Chang1 and Fan-Gang Tseng1,2 1National Tsing Hua University, TAIWAN and 2Academia Sinica, TAIWAN

a - Fundamentals in Microfluidics and Nanofluidics Droplet Microfluidics M1-102.a A NOVEL PARTITIONING PLATFORM TOWARDS THE LOW-COST, RAPIDLY DEPLOYABLE, DIGITAL DETECTION OF SARS-COV-2 Maria Alvarez Amador, Yuhe Jiang, Ling Li, and Eric Brouzes Stony Brook University, USA

M1-103.a DEFORMABILITY-BASED MICROFLUIDIC MICRODROPLET SORTING AS A SCREENING METHOD FOR SINGLE AGAROLYTIC BACTERIAL CELLS Mikihisa Muta1, Kai Saito1, Ryo Iizuka1, Wataru Kawakubo2, Dong Hyun Yoon2, Mei Ito3, Yuji Hatada3, Tetsushi Sekiguchi2, Shuichi Shoji2, and Takashi Funatsu1 1University of Tokyo, JAPAN, 2Waseda University, JAPAN, and 3Saitama Institute of Technology, JAPAN

M1-104.a ENDOTHELIAL-CELL SPROUTING ASSAY WITH MULTIPLE INTERACTING SEEDS AS A PLATFORM TO STUDY ANGIOGENESIS Katarzyna Rojek and Jan Guzowski Polish Academy of Sciences, POLAND

M1-105.a IMAGE ANALYSIS EXPLORATION: CASE FOR DROPLET MICROFLUIDICS Immanuel Sanka, Simona Bartkova, Pille Pata, Olli-Pekka Smolander, and Ott Scheler Tallinn University of Technology, ESTONIA

M1-106.a PARALLEL DROPLET GENERATION OF LINEAR CONCENTRATION GRADIENT FOR ANTIMICROBIAL SUSCEPTIBILITY TESTING OF ESCHERICHIA COLI O157:H7 Jae Seong Kim1, Byungjin Lee1, Heon-Ho Jeong2, Dong-Ho Kim1, Kyoung Han Kim1, and Chang-Soo Lee1 1Chungnam National University, KOREA and 2Chonnam National University, KOREA

M1-107.a TOWARDS HIGH-THROUGHPUT SCREENING FOR DRUG DISCOVERY IN MULTI SPLITTING AND MERGING SYSTEM USING MICROVALVES Sagar N. Agnihotri1,2, Mohammad Reza Raveshi1, Rajneesh Bhardwaj2, and Adrian Neild1 1Monash University, AUSTRALIA and 2Indian Institute of Technology, Bombay (IIT), INDIA

M2-202.a A SAMPLE INJECTION INTERFACE OF MASS SPECTROMETRY UTILIZING FEMTOLITER- DROPLET SHOOTER BY MICROFLUIDICS Yuto Takagi1, Yutaka Kazoe2, and Takehiko Kitamori1,3 1University of Tokyo, JAPAN, 2Keio University, JAPAN, and 3National Tsing Hua University, TAIWAN

M2-203.a DROPLET GENERATOR IN A SINGLE TUBE FOR DNA AMPLIFICATION Shaw-Hwa Parng, Ping-Jung Wu, Yu-Yin Tsai, Ruey-Shyan Hong, and Su-Jan Lee Industrial Technology Research Institute, TAIWAN

M2-204.a FACILE EVAPORATION INDUCED ON SURFACE MANIPULATION OF AQUEOUS DROPLETS AND ITS APPLICATION IN BIOLOGICAL CARGO TRANSPORT Butunath Majhy and Ashis K. Sen Indian Institute of Technology, Madras, INDIA

M2-205.a MANIPULATION OF DROPLETS IN NON-NEWTONIAN FLUID Shamik Hazra1, Sushanta K. Mitra2, and Ashis Kumar Sen1 1Indian Institute of Technology, Madras, INDIA and 2University of Waterloo, CANADA

M2-206.a PERIODIC CONCENTRATION-POLARIZATION BASED FORMATION OF BIOMOLECULE PRECONCENTRATION Sinwook Park, Ramadan Abu-Rjal, Keren Buchnik, Yechezkel Kashi, and Gilad Yossifon Technion – Israel Institute of Technology, ISRAEL

T3-302.a ACTIVE GENERATION OF FEMTOLITER DROPLET IN MICROFLUIDICS USING INKJET NOZZLE Dege Li1, Yi Cao1, Bingfang Huang1, Chao Zheng1, Yonghong Liu1, and Yanzhen Zhang1,2 1China University of Petroleum (East China), CHINA and 2Swinburne University of Technology, AUSTRALIA

T3-303.a DROPLET GENERATORS COMMUNICATION FOR A HIGH THROUGHPUT PRODUCTION Ilyesse Bihi, Pierre Gelin, and Wim De Malsche Vrije Universiteit Brussel, BELGIUM

T3-304.a FAST DROPLET ENRICHMENT USING SPONTANEOUS EMULSIFICATION Piangrawee Santivongskul1, Mao Fukuyama1,2, and Akihide Hibara1 1Tohoku University, JAPAN and 2Japan Science and Technology Agency (JST), JAPAN

T3-305.a MICRO-MAGNETIC-TWEEZERS: A TOOL FOR BIOSEPARATION IN SUB-NANOLITER DROPLETS Simon Dumas, Mathilde Richerd, Marco Serra, and Stéphanie Descroix Institut Curie, FRANCE

T3-306.a PRODUCTION OF MONODISPERSE CAPSULES FOR CONTROLLED SPORE RELEASE Iwona Ziemecka1, Ilyesse Bihi1, Pierre Gelin1, Guy Van Assche2, Suzy Vaupre1, Roberto Teixeira1, Dominique Maes1, and Wim De Malsche1 1Vrije Universiteit Brussel, BELGIUM and 2Devan Chemicals NV, BELGIUM

T4-402.a AUTOMATED MICROFLUIDIC DROPLET GENERATION AND MERGING TO RESOLVE DYNAMICS OF UPTAKE AND SECRETION IN WHITE ADIPOSE TISSUE (WAT) Nan Shi, Md Moniruzzaman, Yvette Kayirangwa, and Christopher J. Easley Auburn University, USA

T4-403.a DROPLET MICROFLUIDIC BASED METHOD FOR IN-SITU CALIBRATION AND DETERMINATION OF RECOVERY RATE OF MICRODIALYSIS Gareth W.H. Evans1, Jameelah Salahuddin1, Wahida T. Bhuiyan1, Brett Warren2, and Xize Niu1,2 1University of Southampton, UK and 2SouthWestSensor Ltd., UK

T4-404.a GENERATION OF AQUEOUS-DROPLET-FILLED HYDROGEL FIBERS AS ORGANOIDS CARRIES USING ALL-IN-WATER MICROFLUIDIC SYSTEM Hui Wang, Hai-Tao Liu, Ya-Qing Wang, Meng-Qian Zhao, Wen-Wen Chen, and Jian-Hua Qin Chinese Academy of Sciences, CHINA

T4-405.a MICROFLUIDIC GENERATION OF WATER-IN-WATER-IN-WATER(-IN-WATER) DOUBLE AND TRIPLE EMULSIONS Morteza Jeyhani1,2, Risavarshni Thevakumaran1,2, Niki Abbasi1,2, Dae Kun Hwang1,2, and Scott S. H. Tsai1,2 1Ryerson University, CANADA and 2St. Michael’s Hospital, CANADA

T4-406.a REAL-TIME IMAGE-BASED DROPLET MEASUREMENT Sepehr Elahi1, Ali Kalantarifard1, Fatemeh Kalantarifard2, and Caglar Elbuken1,3 1Bilkent University, TURKEY, 2Bogazici University, TURKEY, and 3University of Oulu, FINLAND

W5-502.a BINARY CONSTRICTIONS, TIP ELONGATION AND DUTY CYCLE: SHAPE BASED MECHANISMS FOR LABEL-FREE DETECTION IN DROPLETS Afreen Fatima and Amar S. Basu Wayne State University, USA

W5-503.a DROPLET MICROFLUIDIC PLATFORM FOR INTRACELLULAR PHASE SEPARATION EXPERIMENTS Katherine Chan1,2, Maryam Navi1,2, Jennifer Kieda1,2, and Scott S.H. Tsai1,2 1Ryerson University, CANADA and 2St. Michael’s Hospital, CANADA

W5-504.a GENERATION OF COMPLEX EMULSIONS USING MONOLITHIC, DUAL- MATERIAL 3D- PRINTED MICROFLUIDIC DEVICES Jin Li, Pantelitsa Dimitriou, Oliver Castell, and David Barrow Cardiff University, UK

W5-505.a MOLECULAR REORIENTATION OF CHOLESTERIC DROPLET INDUCED BY STRAIN FOR FLEXIBLE SENSING APPLICATION Shuting Xie, Mingliang Jin, Ruizhi Yang, Guofu Zhou, and Lingling Shui South China Normal University, CHINA

W5-506.a SELF-EMULSIFICATION IN LIQUID CRYSTAL DROPLETS Ruizhi Yang, Yueming Deng, Shuting Xie, Qi An, and Lingling Shui South China Normal University, CHINA

W6-602.a COMPUTER VISION APPLIED TO MEMBRANE DISPLACEMENT TRAP ARRAYS FOR AUTOMATED DROPLET CONTROL AND MANIPULATION Michael Yeh1,2, Jason Harriot1, Supriya Padmanabhan1, and Don L. DeVoe1 1University of Maryland, College Park, USA and 2National Cancer Institute, USA

W6-603.a DROPLET SQUEEZING FOR HIGHLY EFFECTIVE GENE DELIVERY INTO HUMAN T LYMPHOCYTES Byeongju Joo, Hasung Lee, Seung Gyu Yun, and Aram Chung Korea University, KOREA

W6-604.a GENERATION OF SPHEROIDS USING AN AQUEOUS TWO-PHASE SYSTEM DROPLET MICROFLUIDIC PLATFORM Jennifer Kieda1,2, Morteza Jeyhani1,2, Maryam Navi1,2, Katherine Chan1,2, and Scott S.H. Tsai1,2 1Ryerson University, CANADA and 2St. Michael’s Hospital, CANADA

W6-605.a MONITORING OF AMMONIA IN NATURAL WATERS USING A VERSATILE, PROGRAMMABLE DROPLET MICROFLUIDIC PLATFORM Wahida Bhuiyan1, Evanthia Papadoupoulou2, Sharon Coleman2, Matthew Pearson2, Adrian Nightingale1, Gareth Evans1, and Xize Niu1,2 1University of Southampton, UK and 2SouthWestSensor Ltd., UK

W6-606.a SIMULTANEOUS DROPLET FORMATION VIA GRAVITY-INDUCED FLOW WITH IN-SERIES DROPLET GENERATING JUNCTIONS Khashayar R. Bajgiran, Riad Elkhanoufi, James A. Dorman, and Adam T. Melvin Louisiana State University, USA

Th7-702.a CONTINUOUS GENERATION OF CELL-LADEN MICROGELS THROUGH DETERMINISTIC LATERAL DISPLACEMENT ARRAYS Naotomo Tottori and Takasi Nisisako 1Kyushu University, JAPAN and 2Tokyo Institute of Technology, JAPAN

Th7-703.a DROPLET-ASSISTED PHASE SEPARATION BY INTEGRATED SILICON ELECTROSPRAY NANO-EMITTER FOR NEUROCHEMICAL SENSING Yan Zhang, Weihua Shi, Insu Park, Sungho Kim, Christopher Brenden, Hrishikesh Iyer, Prasoon Jha, Rashid Bashir, and Yurii Vlasov University of Illinois, Urbana-Champaign, USA

Th7-704.a HIGH-THROUGHPUT SORTING OF NANOLITER DROPLETS USING AN ELECTRODE ARRAY WITH A SLANTED MICROCHANNEL Mun Hong Loo1, Yuta Nakagawa1, Akihiro Isozaki1,2, and Keisuke Goda1,3,4 1University of Tokyo, JAPAN, 2Kanagawa Institute of Industrial Science and Technology, JAPAN, 3University of California, Los Angeles, USA, and 4Wuhan University, China

Th7-705.a MONITORING OF REACTION KINETICS THROUGH THE SYNCHRONIZED RELEASE OF LIPOSOMAL CARGO IN DOUBLE EMULSIONS Ariane Stucki, Petra Jusková, Nicola Nuti, and Petra S. Dittrich ETH Zürich, Basel, SWITZERLAND

Th7-706.a SPACE-FILLING OPEN MICROFLUIDICS FOR DROPLET COLLECTION: GENERALIZED DESIGN OF FRACTAL HYPERBRANCHED CHANNELS Hiroyuki Kai Tohoku University, JAPAN

Th8-801.a A MICROFLUIDIC MAGNETIC EXTRACTOR FOR MAGNETIC BEAD SEPARATION IN DROPLETS Junyue Chen1,2, Weiliang Shu1, Ying Tan2, Hongtao Feng1, Yimo Yan2, and Yan Chen1 1Chinese Academy of Sciences, CHINA and 2Tsinghua University, CHINA

Th8-802.a CONTROLLED ACTUATION OF SELF-PROPELLED DROPLETS Loïc Coudron, Clément Lemenu, Kevin Lemaine, Daniel McCluskey, Christabel Tan, Ian Munro, Arne Erik Holdo, Mark Tracey, and Ian Johnston University of Hertfordshire, UK

Th8-803.a ELECTROCOALESCENCE OF MICRODROPLETS WITH ACTIVE PAIRING Kaijian Zhu1,2, Wen Yue1, and Dahai Ren2 1China University of Geosciences, CHINA and 2Tsinghua University, CHINA

Th8-804.a HYBRID MICROGELS PRODUCED VIA DROPLET MICROFLUIDICS FOR NANOPARTICLE ENCAPSULATION AND DRUG DELIVERY Bruna G. Carvalho1, Thiago B. Taketa1, Bianca B.M. Garcia2, Sang W. Han2, and Lucimara G. de la Torre1 1University of Campinas, BRAZIL and 2São Paulo Federal University, BRAZIL

Th8-805.a OPTICAL ACCESSIBILITY IMPROVEMENTS FOR THE CHARACTERIZATION OF THE NANOPEDE Edo A.G. de Kruiff1, Chris L. Kennedy2, Corentin B.M. Tregouet3, Alfons van Blaaderen2, Jan C.T. Eijkel1, and Mathieu Odijk1 1University of Twente, THE NETHERLANDS, 2Utrecht University, THE NETHERLANDS, and 3University of Rennes 1, FRANCE

Th8-806.a SPRING-POWERED PORTABLE SYRINGE PUMP THAT PROVIDES CONSTANT FLOW RATE Won Han and Joong Ho Shin Pukyong National University, KOREA

a - Fundamentals in Microfluidics and Nanofluidics Digital Microfluidics M2-207.a ALL-IN-ONE DIGITAL MICROFLUIDIC SYSTEM FOR MOLECULAR DIAGNOSIS BASED ON THE LOOP-MEDIATED ISOTHERMAL AMPLIFICATION Siyi Hu1, Chao Yang2, Yuhan Jie2, Haifei Yang2, Yang Su1,2, and Hanbin Ma1,2 1Chinese Academy of Sciences, CHINA and 2ACXEL TECH LTD, UK

T3-307.a OPEN SURFACE DROPLET MANIPULATION AND MIXING BY FERROFLUID INSTABILITIES Vahid Nasirimarekani1, Fernando Benito-Lopez1, and Lourdes Basabe-Desmonts1,2 1University of the Basque Country, SPAIN and 2Basque Foundation of Science, IKERBASQUE, SPAINSPAIN

a - Fundamentals in Microfluidics and Nanofluidics Centrifugal Microfluidics M1-108.a RELIABLE LIQUID REAGENT HANDLING AND ROTATIONAL RELEASE FOR CENTRIFUGAL SAMPLE-TO-ANSWER AUTOMATION Yao Lu, Darren McAuley, Rohit Mishra, David Boyle, and Jens Ducrée Dublin City University, IRELAND

M2-208.a VISCOSITY INDEPENDENT FLOW FOR PLANAR CHROMATOGRAPHIC IMMUNOASSAYS BY CENTRIFUGAL MICROFLUIDICS Daniel M. Kainz1,2, Susanna M. Früh1,2, Tobias Hutzenlaub1,2, Roland Zengerle1,2, and Nils Paust1,2 1University of Freiburg, GERMANY and 2Hahn-Schickard, GERMANY

T4-407.a AUTOMATED CELL CULTURE AND ACTIVATION ASSAY USING CENTRIFUGAL MICROFLUIDIC PLATFORM Lidija Malic1, Liviu Clime1, Jamal Daoud1, Abdelrahman Elmanzalawy1, Ljuboje Lukic1, Huailo Lee2, Yuh-Tyng Tsai2, Pei-Shin Jiang2, and Teodor Veres1 1National Research Council, CANADA and 2Industrial Technology Research Institute, TAIWAN

W5-507.a AUTOMATED LIBRARY PREPARATION FOR NEXT GENERATION SEQUENCING OF IMMUNOGLOBULIN GENE REARRANGEMENTS BY CENTRIFUGAL MICROFLUIDICS Jacob F. Hess1, Michaela Kotrová2, Silvia Calabrese1, Tobias Hutzenlaub1,3, Roland Zengerle1,3, Monika Brüggemann2, and Nils Paust1,3 1Hahn-Schickard, GERMANY, 2University Medical Center Schleswig Holstein, GERMANY, and 3University of Freiburg, GERMANY

W6-607.a FULLY INTEGRATED LTA ASSAY ON CENTRIFUGAL MICROFLUIDIC DEVICE Jungmin Kim1,2, Chi-Ju Kim1, Jonathan Sabaté del Río1, and Yoon-Kyoung Cho1,2 1Ulsan National Institute of Science & Technology (UNIST), KOREA and 2Institute for Basic Science (IBS)< KOREA

Th7-707.a PNEUMATICALLY CONTROLLED DROPLET GENERATION ON A CENTRIFUGAL MICROFLUIDIC PLATFORM Liviu Clime, Lidija Malic, Luke Lukic, Matthias Geissler, and Teodor Veres National Research Council, CANADA

Th8-807.a PURIFICATION OF DNA FRAGMENTS USING PNEUMATIC CONTROL COUPLED TO CENTRIFUGAL MICROFLUIDICS Daniel Brassard, Jimin Guo, Maxence Mounier, Jason Ferreira, Mojra Janta-Polczynski, and Teodor Veres National Research Council, CANADA

a - Fundamentals in Microfluidics and Nanofluidics Acousto- and Magnetofluidics M1-109.a RAPID MUTINODAL ACOUSTIC TRAPPING OF EXTRACELLULAR VESICLES FOR DOWNSTREAM MASS SPECTROMETRY ANALYSIS Axel Broman, Lotta Happonen, Frida Palm, Oonagh Shannon, Johan Malmström, and Thomas Laurell Lund University, SWEDEN

M2-209.a REDUCING TAYLOR DISPERSION WITH ACOUSTIC STREAMING Pierre Gelin, Dominique Maes, and Wim De Malsche Vrije Universiteit Brussel, BELGIUM

T3-308.a A SINGLE CELL MANIPULATION TOOL BASED ON GIGAHERTZ ACOUSTIC-STREAMING TWEEZERS Ke Jin, Yang Yang, Yang Bai, Wei Wei, and Xuexin Duan State Key Laboratory of Precision Measuring Technology & Instruments, CHINA

W5-508.a BINARY PARTICLE ACOUSTOPHORESIS SEPARATION BASED ON NODAL POSITION ADJUSTMENT THROUGH PDMS WALL Sinan Yigit1, Song-I Han2, Younghak Cho3, and Arum Han2 1Necmettin Erbakan University, TURKEY, 2Texas A&M University, USA, and 3Seoul National University of Science & Technology, KOREA

W6-608.a FREQUENCY TUNABLE LABEL-FREE SURFACE ACOUSTIC WAVE-BASED FLOW SENSOR Aurore Quelennec, Jason J. Gorman, and Darwin R. Reyes National Institute of Standards and Technology (NIST), USA

Th7-708.a MOTILITY-BASED SPERM SELECTION USING ACOUSTOFLUIDICS Junyang Gai, Reza Nosrati, and Adrian Neild Monash University, AUSTRALIA

Th8-808.a QUANTIFYING THE ACOUSTIC FIELD IN A MICROCHANNEL USING MICROSWIMMERS AS MEASUREMENT PROBES Minji Kim1, Rune Barnkob2, and J. Mark Meacham1 1Washington University, St. Louis, USA and 2Technical University of Munich, GERMANY

a - Fundamentals in Microfluidics and Nanofluidics Capillary Microfluidics M1-110.a MULTILEVEL PASSIVE MICROFLUIDICS FOR ELECTROCHEMICAL BIOSENSORS Pooya Azizian1,2, Adrián Ortega1, Jordi Ricart1, Jasmina Casals-Terré2, and Joan M. Cabot1 1Leitat Technological Center, SPAIN and 2Technical University of Catalonia, SPAIN

M2-210.a MULTISCALE MODELLING AND COMPUTATIONAL DESIGN OF FLUID FLOW AND MASS TRANSPORT IN 3D PRINTED LAB-ON-CHIPS Agnese Piovesan, Bart Dequeker, Ruben Dochy, Cesar Parra Cabrera, Clement Achille, Rob Ameloot, Pieter Verboven, and Bart Nicolai KU Leuven, BELGIUM

T3-309.a 3D PRINTED AXISYMMETRIC FLOW-FOCUSING DEVICE USING FUSED SILICA CAPILLARY TUBES Keisuke Sugahara and Shoji Takeuchi University of Tokyo, JAPAN

T3-310.a OPEN-CHANNEL CAPILLARY TREES AND CAPILLARY PUMPING Jing J. Lee, Jean Berthier, Kathleen E. Kearney, Erwin Berthier, and Ashleigh B. Theberge University of Washington, USA T4-409.a 3D-PRINTING AND COMPUTATIONAL FLUID DYNAMICS 'MEET' PAPER-BASED MICROFLUIDICS FOR ENHANCED FLOW CONTROL IN DIFFUSIVE SENSORS Joan Antoni López, Pau Fernández, Pouya Mehdrel, and Jasmina Casals-Terré Technical University of Catalonia, SPAIN

T4-410.a POLY(N-ISOPROPYL ACRYLAMIDE) COATING OF MICROCHANNELS AND BACTERIAL SAMPLE LOADING VIA CAPILLARY-DRIVEN FLOW Sammer-ul Hassan1, Steve Carter2, Sehaj Singh2, Edward Dyson2, Stephen Rimmer2, and Xunli Zhang1 University of Southampton, UK and 2University of Bradford, UK

W5-509.a CAPILLARY-DRIVEN LOADING OF HriCFP EXPRESSING ESCHERICHIA COLI INTO MICROCHANNELS Ahmed Donia1, Salma Saeed1, Aamira Tariq1, Zobia Noreen1, Habib Bokhari1, Xunli Zhang2, and Sammer-ul Hassan2 1Comsats University Islamabad, PAKISTAN and 2University of Southampton, UK

W5-510.a PASSIVE FLOW CONTROL IN A LAMINATION-BASED CAPILLARY-DRIVEN MICROFLUIDIC DEVICE Ilhoon Jang1,2 and Charles S. Henry2 1Hanyang University, KOREA and 2Colorado State University, USA

W6-609.a DIGITAL MANUFACTURING OF FUNCTIONAL AUTONOMOUS CAPILLARIC CIRCUITS USING HYDROPHILIC RESINS AND A 3D PRINTER Ahmad Sohrabi Kashani, Vahid Karamzadeh, Oriol Ymbern Llorens, Andy Ng, and David Juncker McGill University, CANADA

W6-610.a SIGNAL AMPLIFICATION IN A LATERAL FLOW ASSAY ENABLED BY A CAPILLARY VALVE AND SELF-ACTUATING ELEVATOR VALVE Caitlin E. Anderson, Joshua D. Bishop, Andrew K. Miller, Benjamin D. Grant, Toan Huynh, David M. Cate, Bernhard H. Weigl, and Kevin P. Nichols Intellectual Ventures Laboratory, USA

Th7-709.a INCORPORATING FLOW CONTROL FUNCTIONALITY IN MICROFLUIDIC PAPER-BASED ANALYTICAL DEVICES USING PLASMA PROCESSES Nikhil Raj, Victor Breedveld, and Dennis W. Hess Georgia Institute of Technology, USA

Th7-710.a THREAD AS A PRECISE SAMPLING AND DELIVERY PLATFORM FOR IMPLANTABLE OR INGESTIBLE APPLICATIONS H. Rezaei Nejad, Aydin Sadeqi, and Sameer Sonkusale Tufts University, USA

Th8-809.a LIQUID ATOMIZATION IN PERIODIC ELECTRO-PULSATING MODE. INDIRECT MEASUREMENT OF THE ELECTRIC FIELD ON THE OSCILLATING MENISCUS Antonio J. Hijano1, Ignacio G. Loscertales1, and Francisco J. Higuera2 1Universidad de Málaga, SPAIN and 2Universidad Politecnica de Madrid, SPAIN

a - Fundamentals in Microfluidics and Nanofluidics Nanofluidics/Nanofluidic Phenomena M1-111.a GENERATION OF NANOMETER-SCALE GEOMETRICAL GAS-LIQUID INTERFACES IN HYDROPHILIC/HYDROPHOBIC PATTERNED NANOCHANNELS Hiroto Kawagishi1, Shuichi Kawamata1, and Yan Xu1,2 1Osaka Prefecture University, JAPAN and 2Japan Science and Technology Agency (JST), JAPAN

M2-211.a INTEGRATED IONIC ELECTRONICS BASED ON HORIZONTALLY-ALIGNED CARBON NANOTUBES Ran Peng1, Yueyue Pan1, Zhi Li2, Shuailong Zhang1, Aaron R. Wheeler1, Shirley Tang2, and Xinyu Liu1 1University of Toronto, CANADA and 2University of Waterloo, CANADA

T3-311.a INTEGRATED MICRO- AND NANOFLUIDIC DEVICES FOR REAL-TIME MONITORING OF HEPATITIS B VIRUS CAPSID ASSEMBLY Michael P. Kappler, Panagiotis Kondylis, Caleb Starr, Adam Zlotnick, and Stephen C. Jacobson Indiana University, USA

T4-411.a LATERAL MIGRATION OF DOUBLETS IN UNTREATED WHOLE BLOOD Jian Zhou and Ian Papautsky University of Illinois, Chicago, USA

W5-511.a NANOFLUIDIC DEVICE FOR SURFACE CHARGE MEASUREMENT OF NANOPARTICLES USING TUNABLE ELECTROSTATIC LANDSCAPE Imman I. Hosseini, Zezhou Liu, Walter Reisner, and Sara Mahshid McGill University, CANADA

W6-611.a TRANSPORT OF VISCOUS FLUID THROUGH MICRO- AND NANO-POROUS MEDIA Md Minhajul Islam and D. Jed Harrison University of Alberta, CANADA

Th8-810.a A SENSE-REACT-SENSE NANOFLUIDIC SYSTEM FOR PERFORMING REACTIONS ON SINGLE VIRUS CAPSIDS Mi Zhang, Caleb Starr, Zhongchao Zhao, Adam Zlotnick, and Stephen C. Jacobson Indiana University, USA

a - Fundamentals in Microfluidics and Nanofluidics Modeling/Numerical Simulation M1-112.a COMPUTATIONAL FLUID DYNAMIC SIMULATION FOR THE STENOSIS MICROFLUIDIC THROMBOSIS MODEL CHARACTERIZATION Yunduo Charles Zhao1, Parham Vatankhah1, Tiffany Goh1,2, and Lining Arnold Ju1,2 1University of Sydney, AUSTRALIA and 2Heart Research Institute, AUSTRALIA

M1-113.a SHAPE DEPENDENT MODEL-BASED APPROACH FOR ELASTIC MODULI ESTIMATION OF BIOLOGICAL CELLS IN FLOW Gangadhar Eluru, Ramya Shekhar, and Sai Siva Gorthi Indian Institute of Science, INDIA

M2-212.a COMPUTATIONAL MODELLING OF FLOW AND DRUG TRANSPORT IN A MICROFLUIDIC DEVICE FOR SPHEROID CULTURES Sina Kheiri, Eugenia Kumacheva, and Edmond W.K. Young University of Toronto, CANADA

M2-213.a SURFACE TEXTURE MODULATES WALL SLIP IN MICROFLUIDIC FLOWS Siyu Chen and Joe Fujiou Lo University of Michigan, Dearborn, USA

T3-312.a CONCENTRATION GRADIENTS INSIDE MICRODROPLETS Christian F. Chamberlayne, Juan Santiago, and Richard N. Zare Stanford University, USA

T3-313.a TOWARD THE CHARACTERIZATION OF COMPLEX MICROVESSEL NETWORKS VIA IN-LINE FLOW RATE SENSING Michael A. Daniele1,2, Vladimir A. Pozdin3, Patrick Erb1,2, and McKenna Downey1 1North Carolina State University, USA, 2University of North Carolina, Chapel Hill, USA, and 3Florida International University, USA

T4-412.a CREATIVE SHAPING OF 2D FLOW AND CONCENTRATION PROFILES IN MICROFLUIDIC CHAMBERS Etienne Boulais and Thomas Gervais Polytechnique Montréal, CANADA

W5-512.a ENHANCING MICROMIXING CAPABILITIES OF FLEXIBLE FLUOROPOLYMER MICROCAPILLARY FILMS WITH 3D PRINTED TEMPLATES: A COMPUTATIONAL FLUID DYNAMICS ANALYSIS Kirandeep K. Gill1, Patrick Hester2, Pedro Estrela1, and Nuno M. Reis1 1University of Bath, UK and 2Lamina Dielectrics Ltd., UK

W6-612.a NUMERICAL SIMULATION AND EXPERIMENTAL ANALYSIS OF INERTIAL CELL FOCUSING IN A CONTRACTION-EXPANSION ARRAY (CEA) MICROCHANNEL Ali C. Atik, Ender Yıldırım, and Haluk Külah Middle East Technical University, TURKEY

Th7-711.a 2D PHASE-FIELD SIMULATION AND EXPERIMENTAL VALIDATION OF DROPLET FORMATION IN A FLOW-FOCUSING JUNCTION Ali C. Atik, Ender Yıldırım, and Haluk Külah Middle East Technical University, TURKEY

Th7-712.a NUMERICAL MODELING OF SEQUENTIAL SEGMENTATION FOR ENHANCEMENT OF MICROMIXING Ibragim Abu Dagga1,2 and Mohamed Abdelgawad1 1American University of Sharjah, UAE and 2Khalifa University of Science and Technology, UAE

Th8-811.a BEHAVIOR OF PHASE CHANGE SLURRY IN A MICROCHANNEL Vikram Soni, Hannah McPhee, Sepehr Saber, Jason Riordon, and David Sinton University of Toronto, CANADA

Th8-812.a RESIDENCE TIME DISTRIBUTION IN MICROMIXERS: SCALE-UP EFFECTS Harrson S. Santana1 and João L. Silva Jr.2 1University of Campinas, BRAZIL and 2Federal University of ABC, BRAZIL

a - Fundamentals in Microfluidics and Nanofluidics Others M1-114.a HIGH-THROUGHPUT SPERM SORTING BY A FLAT RHEOTAXIS MICROFLUID DEVICE Suei-Shen Wang1 and Fan-Gang Tseng1,2 1National Tsing Hua University, TAIWAN and 2Academia Sinica, TAIWAN

M2-214.a TO STICK OR NOT TO STICK: PREDICTING PARTICLE CAPTURE ON A SURFACE IN A MICROCHANNEL Donatien Mottin1,2, Florence Razan2, Frédéric Kanoufi3, and Marie-Caroline Jullien1 1University of Rennes, FRANCE, 2École Normale Supérieure de Rennes, FRANCE, and 3Université de Paris, FRANCE

T3-314.a IMPROVED UNDERSTANDING OF PARTICLE MIGRATION IN SHEAR THINNING VISCOELASTIC FLUID Shamik Hazra1, Sushanta K. Mitra2, and Ashis Kumar Sen1 1Indian Institute of Technology, Madras, INDIA and 2University of Waterloo, CANADA

T4-413.a CONCENTRATION-DEPENDENT LOSS OF CHARGED ANALYTES IN PAPERFLUIDIC DEVICES Siddhant Jaitpal1, Priyanka Naik1, Shashwat Banerjee2, and Debjani Paul1 1Indian Institute of Technology, Bombay, INDIA and 2Maharashtra Institute of Medical Education and Research Medical College, INDIA

W5-513.a DIFFERENTIAL 3D-VISCOELASTIC FOCUSING OF PARTICLES IN A RECTANGULAR MICROFLUIDIC CHANNEL Ludovica Barilla, Jian Zhou, Zhangli Peng, and Ian Papautsky University Illinois, Chicago, USA

W6-613.a DNA CONCENTRATION WAVE FORMATION IN PILLAR ARRAYS Oskar E. Ström, Jason P. Beech, and Jonas O. Tegenfeldt Lund University, SWEDEN

Th7-713.a EFFECT OF DEAN FLOWS ON SUB-MICRON PARTICLES IN LOW ASPECT RATIO MICROCHANNELS – ANALYSIS OF DFF Suhanya Duraiswamy1 and Lin Yue Lanry Yung2 1Indian Institute of Technology, Hyderabad, INDIA and 2National University of Singapore, SINGAPORE

Th8-813.a EFFECTS OF PARTICLE SIZE AND FLUID ELASTICITY ON ELASTO-INERTIAL MIGRATION IN SPIRAL CHANNEL Hua Gao, Jian Zhou, and Ian Papautsky University of Illinois, Chicago, USA

a - Fundamentals in Microfluidics and Nanofluidics Industrial Benefactor M2-215.a LITHOGRAPHY SOLUTIONS FOR MICROFLUIDICS AND BIOTECH Charles Turk OAI, USA

T3-383.a FROM SURFACTANTS TO HYDROGEL BEADS TO EMULSION TEMPLATING KITS Robert Lintner, Brian O’Day, Anne-Milda Pu and Roger Nassar RAN Biotechnologies Inc.

a - Fundamentals in Microfluidics and Nanofluidics Late News M1-172.a ARRESTED COALESCENCE OF LIQUID MARBLES TRIGGERED BY ELECTROSTATICS Yage Zhang1, Chentianyi Yang1, Shuai Yuan1, Xiaoxue Yao2, and Ho Cheung Shum1 1University of Hong Kong, HONG KONG and 2Shenzhen University, CHINA

M1-173.a RECTIFIED AC ELECTROOSMOSIS INDUCED BY SURFACE CONDUCTANCE AROUND INSULATING MICROPOSTS Victor Calero1, Raul Fernández-Mateo1, Pablo García-Sánchez2, Antonio Ramos2, and Hywel Morgan1 1University of Southampton, UK and 2Universidad de Sevilla, SPAIN

M2-272.a A NOVEL MICROFLUIDIC DEVICE TO FLEXIBLY GENERATE GROOVED MICROFIBERS AS ANISOTROPIC SCAFFOLDS Meng-Qian Zhao, Hai-Tao Liu, Hui Wang, Ting-Ting Tao, and Jian-Hua Qin Chinese Academy of Sciences, CHINA

M2-273.a DIGITAL-WGS: AUTOMATED, HIGHLY EFFICIENT WHOLE-GENOME SEQUENCING OF SINGLE CELLS BY DIGITAL MICROFLUIDICS Qingyu Ruan1, Weidong Ruan1, Xiaoye Lin1, Zhi Zhu1, and Chaoyong Yang1,2 1Xiamen University, CHINA and 2Shanghai Jiao Tong University, CHINA

T3-373.a CELL MANIPULATION VIA ACOUSTIC FORCES IN A SPHERICAL MICROCHAMBER Bettina Sailer, Rune Barnkob, and Oliver Hayden Technical University of Munich, GERMANY

T3-374.a DOUBLE MONOCLONAL DISPLAY FOR HIGHLY EFFICIENT PEPTIDE SCREENING Junxia Wang, Yuyu Tan, Jiajun Ling, Mingxia Zhang, Wenli Liu, Mengjiao Huang, Jia Song, Ao Li, Yanling Song, Zhi Zhu, and Chaoyong Yang Xiamen University, CHINA

T4-473.a HIGH RESOLUTION EXOSOME TYPING METHOD FOR CANCER DIAGNOSIS Bingqian Lin1, Lingling Wu2, Zhi Zhu1, Yanling Song1, and Chaoyong Yang1,2 1Xiamen University, CHINA and 2Shanghai Jiao Tong University, CHINA

T4-474.a HIGHLY EFFICIENT ACOUSTOPHORETIC SINGLE CELL-SUPERNATANT SEPARATION INSIDE NANOLITER DROPLETS Michael Gerlt1, Dominik Haidas2, Alexandre Ratschat1, Philipp Suter1, Petra Dittrich2, and Jürg Dual1 1ETH Zürich, SWITZERLAND and 2ETH Zürich, Basel, SWITZERLAND

W5-572.a DYNAMIC FORMATION OF MULTIPLE PRECONCENTRATED MOLECULE PLUGS Barak Sabbagh1, Elad Stolovicki2, Sinwook Park1, and Gilad Yossion1 1Technion - Israel Institute of Technology, ISRAEL and 2Harvard University, USA

W5-573.a HIGH THROUGHPUT, MOBILE DIGITAL FLUORESCENCE DROPLET ASSAYS USING TIME DOMAIN EXCITATION MODULATION Zijian Yang, Yasemin Atiyas, and David Issadore University of Pennsylvania, USA

W6-674.a MAPPING THE PHASE DIAGRAM OF DNA HYDROGELS WITH DROPLET MICROFLUIDICS Guilhem Mariette1,2, Nicolas Lobato-Dauzier2, Robin Deteix2, Mia Zhang2, Shu Okumura2, Yusuke Sato3, Masahiro Takinoue4, Teruo Fujii2, and Anthony J. Genot2 1Ecole Normale Supérieure, FRANCE, 2University of Tokyo, JAPAN and 3Tohoku University, JAPAN, and 4Tokyo Institute of Technology, JAPAN

Th7-772.a ACCELERATING THE FINITE-ELEMENT METHOD FOR REACTION-DIFFUSION SIMULATIONS ON GPUs WITH CUDA Hedi Sellami, Leo Cazenille, Teruo Fujii, Masami Hagiya, Nathanael Aubert-Kato, and Anthony J. Genot University of Tokyo, JAPAN

Th7-773.a NOVEL APPROACH FOR ADVANCED PERSONALIZED CANCER TREATMENT Anna Luise Grab1, Ramesh Utharala1, Thorsten Cramer2,3, Julio Saez-Rodrigue4, Nicolas Peschke1, Denes Türei1,4, Wenwei Ma1, Vida Vafaizdah1, Federica Eduati5, and Christoph Merten1,6 1European Molecular Biology Laboratory, GERMANY, 2RWTH Aachen, Germany, 3Maastricht University, THE NETHERLANDS, 4Faculty of Medicine of Heidelberg, GERMANY, 5Eindhoven University of Technology, THE NETHERLANDS, and 6Swiss Federal Institute of Technology Lausanne, SWITZERLAND

Th8-871.a VACUUM POUCH MICROFLUIDIC SYSTEM FOR THE APPLICATION OF DIGITAL PCR Cheng-Je Lee and Yu-Hsiang Hsu National Taiwan University, TAIWAN

b - Micro- and Nanoengineering Microscale Fabrication, Patterning, and Integration M1-115.b A VACUUM-DRIVEN MICROFLUIDIC ARRAY FOR MULTI-STEP SAMPLE DIGITALIZATION Jiumei Hu, Liben Chen, Hui Li, Kuangwen Hsieh, Pengfei Zhang, and Tza-Huei Wang Johns Hopkins University, USA

M1-116.b ENGINEERING MULTIPLY ENCAPSULATED MICROGELS FOR CONTROLLED LONG-TERM DRUG DELIVERY Jing Liu, Cassidy Marie Enloe, Ralph McBride, John S. Oakey, and Katie Li-Oakey University of Wyoming, USA

M1-117.b FULLY PRINTED PIEZOELECTRIC DEVICES Marc Alique1, Marcos Duque2, Claudia Delgado1, Paul Lacharmoise1, Gonzalo Murillo2, and Ana Moya1 1Fundació Eurecat, SPAIN and 2IMB-CNM (CSIC), SPAIN

M1-118.b NANOPARTICLE DETECTION BY SOLID-STATE NANOPORE INTEGRATED INTO A REUSABLE MICROFLUIDIC DEVICE Izadora Mayumi Fujinami Tanimoto1,2, Benjamin Cressiot3, Jean Roman1, Nathalie Jarroux1,2, Gilles Patriarche1, Bruno Le Pioufle1, Juan Pelta1,2,3, and Laurent Bacri1,1 1Université Paris-Saclay, FRANCE, 2Université d'Evry, FRANCE, and 3CY Cergy Paris Université, FRANCE

M1-119.b WHY ARE 3D-PRINTED MOLDS INHIBITING PDMS CURING? Bastien Venzac1, Shanliang Deng1, Ziad Mahmoud2, Aufried Lenferink1, Fabrice Bray2, Cees Otto1, Christian Rolando2, and Séverine Le Gac1 1University of Twente, THE NETHERLANDS and 2Université de Lille, FRANCE

M2-216.b AN INTEGRATED FLEXIBLE PLATFORM WITH PRINTED ORGANIC ELECTROCHEMICAL AND FIELD-EFFECT TRANSISTORS FOR BIOCHEMICAL SENSING Silvia Demuru1, Khalil Chennit2, Vincent Noël2, Benoit Piro2, Giorgio Mattana2, and Danick Briand1 1École Polytechnique Fédérale de Lausanne (EPFL), SWITZERLAND and 2Paris Diderot University, FRANCE

M2-217.b ETCHED SILICON µDICER FOR UNIFORM SECTIONING OF TISSUE SAMPLES Seth C. Cordts, Saisneha Koppaka, Nicolas Castaño, and Sindy K.Y. Tang Stanford University, USA

M2-218.b IN-SITU 3D WRITING OF MICROELECTRODES BASED ON PLASMA-ASSISTED MICROPLATING Shinya Sakuma, Natsumi Basaki, Keita Ichikawa, and Yoko Yamanishi Kyushu University, JAPAN

M2-219.b OPTICAL GROWTH AND PATTERNING OF HIGHLY CONDUCTIVE SILVER ON ULTRASMOOTH NANOCELLULOSE PAPER Yueyue Pan, Sina Kheiri, Zhen Qin, Binbin Ying, Peng Pan, Ran Peng, and Xinyu Liu University of Toronto, CANADA

T3-315.b ANALYSIS OF INSERTION FORCE OF POLYMER MICRONEEDLES WITH HIGH ASPECT RATIO Yukihiro Kanda1, Hiroaki Takehara1,2, and Takanori Ichiki1,2 1University of Tokyo, JAPAN and 2Kawasaki Institute of Industry Promotion, JAPAN

T3-316.b FABRICATION AND CHARACTERIZATION OF 3D MICROFLUIDICS BLADES TO IMPROVE THE CUTTING OF BIOLOGICAL MATERIALS Saisneha Koppaka, Lucas R. Blauch, Kevin S. Zhang, Seth C. Cordts, and Sindy K.Y. Tang Stanford University, USA

T3-317.b MECHANICALLY DIRECTING THE DIFFERENTION AND ORGANISATION OF STEM CELL TO RECAPITULATE KEY LIVER FUNCTION Mary Okesola, Tamir S. Rashid, and Ciro Chiappini King's College London, UK

T3-318.b PIXELATED CHEMICAL DISPLAYS FOR DRY SURFACE PATTERNING IN INDUSTRIAL ROLL-TO-ROLL PROCESSES Pierre-Alexandre Goyette1 and Thomas Gervais1,2 1École Polytechnique de Montréal, CANADA and 2Université de Montréal, CANADA

T4-414.b 2D TO 3D TRANSFORMATION OF PEN-DRAWING Sumin Lee1, Seo Woo Song1, Jun Kyu Choe2, Na-Hyang Kim2, Junwon Kang1, Ju-Young Kim2, Jiyun Kim2, and Sunghoon Kwon1 1Seoul National University, KOREA and 2Ulsan National Institute of Science & Technology (UNIST), KOREA

T4-415.b BIOMIMETIC MICROFLUIDIC SYSTEM FOR EVALUATION OF SPERM NAVIGATION BEHAVIOR Yimo Yan, Qiqi Fu, Boxuan Zhang, and Ran Liu Tsinghua University, CHINA

T4-416.b FABRICATION AND CHARACTERIZATION OF LITHIUM DOPED NAFION MEMBRANE AND HOLLOW GLASSY CARBON MICRONEEDLE FOR MICROPUMP BASED DRUG DELIVERY Arkaprava Datta, Richa Mishra, Shatavisha Biswas, Jhimli Sarkar Manna, Riddhiman Dhar, and Tarun Kanti Bhattacharyya Indian Institute of Technology, Kharagpur, INDIA

T4-417.b METAMOLDING: A MODULAR APPROACH TOWARD LARGE SCALE MICROPATTERNING AND MICROFLUIDICS Jung Y. Han, Pranav Menon, and Don L. DeVoe University of Maryland, College Park, USA

T4-418.b QUANTITATIVE DESIGN STRATEGY OF THE RESOLUTION AND SCREEN AREA OF MICROFLUIDIC REFLECTIVE DISPLAY WITH SUB-PIXELS Jumpei Muramatsu and Hiroaki Onoe Keio University, JAPAN

W5-514.b 360° LIGHT HARVESTING REFLECTOR FULLY INTEGRATED ON MICRLFUIDIC PLATFORM Filippo Storti1,2, Silvio Bonfadini1, and Luigino Criante1 1Istituto Italiano di Tecnologia, ITALY and 2Politecnico di Milano, ITALY

W5-515.b CELL TRANSPORT WITH ADDRESSABLE MICROCHANNEL FORMED BY GEL ACTUATORS Hiroki Wada1, Yuha Koike1, Yoshiyuki Yokoyama2, and Takeshi Hayakawa1 1Chuo University, JAPAN and 2Toyama Industrial Technology Research and Development Center, JAPAN

W5-516.b FABRICATION OF ACTIVE MICROFLUIDICS ON GLASS WITH SEMICONDUCTOR GRADE MATERIAL Boshen Liang1,2, Grim Keulemans1, Brice Eychenne1, Shruti Jambaldinni1, David Cheyns1, Tim Stakenborg1, Veronique Rochus1, Paul Heremans1,2, and Lei Zhang1 1IMEC, BELGIUM and 2KU Leuven, BELGIUM

W5-517.b MICRO-PATTERNED PAPER FOR DRUG TESTING OF 3D TUMOR MODELS Bisan Samara1, Pavithra Sukumar1, and Mohammad A. Qasaimeh1,2 1New York University Abu Dhabi, UAE and 2New York University, USA

W5-518.b RADIOPAQUE HYDROGEL MICROFIBER FOR ARTERIAL EMBOLIZATION Naoki Takakura1, Hiroki Ohta2, Teppei Komatsu2, Yuta Kurashina3, Hirotaka J. Okano2, and Hiroaki Onoe1 1Keio University, JAPAN, 2Jikei University School of Medicine, JAPAN, and 3Tokyo Institute of Technology, JAPAN

W6-614.b 3D PRINTED MULTIPURPOSE ATOMIC FORCE MICROSCOPY PROBES Ayoub Glia, Muhammedin Deliorman, and Mohammad A. Qasaimeh 1New York University Abu Dhabi, UAE and 2New York University, USA

W6-615.b DIGITAL LIGHT PROCESSING-BASED 3D PRINTED HYDROGEL SCAFFOLDS FOR ARTICULAR CARTILAGE TISSUE ENGINEERING Chuan-Yung Wu1, Yun-Jie Hao1, Yu-Chuan Su1, and Fan-Gang Tseng1,2 1National Tsing Hua University, TAIWAN and 2Academia Sinica, TAIWAN

W6-616.b FABRICATION OF HIGHLY ORDERED POLYCAPROLACTONE MICROSPHERES FOR IN VITRO DRUG DELIVERY USING MICROFLUIDIC TECHNOLOGIES Alejandro Forigua, Laila Abelseth, Stephanie M. Willerth, and Katherine S. Elvira University of Victoria, CANADA

W6-617.b MICROFLUIDIC DEVICES FOR PLASMA SEPARATION FABRICATED WITH A HIGH RESOLUTION CUSTOM MADE 3D PRINTER Sandra Garcia-Rey1,2, Gregory P. Nordin1, Lourdes Basabe-Desmonts1,3, Fernando Benito-Lopez1, and Adam T. Woolley2 1University of the Basque Country, SPAIN, 2Brigham Young University, USA, and 3IKERBASQUE, Basque Foundation for Science

W6-618.b STRETCHABLE INERTIAL MICROFLUIDICS Hedieh Fallahi, Jun Zhang, Hoang-Phuong Phan, and Nam-Trung Nguyen Griffith University, AUSTRALIA

Th7-714.b 3D SKIN MICROFLUIDIC PHANTOM FOR IN VITRO WEARABLE TESTING Genís Rabost-Garcia1,2, Oscar Carreras-Gallo1, Valeria Colmena2, Javier Aguilar2, Jaime Punter-Villagrasa2, Francesc X. Muñoz2,3, Josep Farré-Lladós1, and Jasmina Casals-Terré1 1Universitat Politècnica de Catalunya, SPAIN, 2Onalabs Inno-hub S.L., SPAIN, and 3Centro Nacional de Microelectrónica, SPAIN

Th7-715.b DNA MICRO-DISK FOR THE EFFICIENT MANAGEMENT OF DNA-BASED DATA STORAGE Hansol Choi1, Yeongjae Choi1, Amos Chungwon Lee1, Wook Park2, and Sunghoon Kwon1 1Seoul National University, KOREA and 2Kyung Hee University, KOREA

Th7-716.b FOCUSING OF MICROPARTICLES AT LOW REYNOLDS NUMBERS Tianlong Zhang1,2, Yaxiaer Yalikun1, Misuzu Namoto1, Kazunori Okano1, Yo Tanaka3, Ming Li2, and Yoichiroh Hosokawa1 1Nara Institute of Science and Technology, JAPAN, 2Macquarie University, AUSTRALIA, and 3RIKEN, JAPAN

Th7-717.b MULTIPLEXED CONVECTION-ENHANCED KINETICS IN MICROTITER PLATES Iago Pereiro, Anna Fomitcheva Khartchenko, Robert D. Lovchik, and Govind V. Kaigala IBM Research - Europe, SWITZERLAND

Th7-718.b TUNING FIELD NON-UNIFORMITY ACROSS MICROCHANNELS FOR FLOW-THROUGH DIELECTROPHORETIC SEPARATIONS XuHai Huang, Karina Torres-Castro, Walter Varhue, and Nathan S. Swami University of Virginia, USA

Th8-814.b A GENERALIZED SEMI-AUTOMATED RATIONAL DESIGN OF MICROPILLAR ARRAYS FOR MECHANOBIOLOGICAL STUDIES Christopher J. Stubbs1, Samuel O. Sofela2,3, Navajit S. Baban2,3, and Yong-Ak Song2,3 1University of Idaho, USA, 2New York University Abu Dhabi, UAE, and 3New York University, USA

Th8-815.b EASILY-FABRICATED FLUOROPOLYMER CHIPS FOR SENSITIVE LONG-TERM ABSORBANCE MEASUREMENT IN DROPLET MICROFLUIDICS Adrian M. Nightingale1, Sammer-ul Hassan1, Kyriacos Makris2, Wahida T. Bhuiyan1, Terry J. Harvey1, and Xize Niu1,2 1University of Southampton, UK and 2SouthWestSensor Ltd., UK

Th8-816.b FOUR-DIMENSIONAL PHOTONIC MICRO-ACTUATORS FOR MICROFLUIDICS APPLICATIONS Marc del Pozo1, Colm Delaney2, Cees W.M. Bastiaansen1,3, Dermot Diamond4, Albert P.H.J. Schenning1, and Larisa Florea2 1Eindhoven University of Technology, THE NETHERLANDS, 2Trinity College Dublin, IRELAND, 3Queen Mary University of London, UK and 4Dublin City University, IRELAND

Th8-817.b NanoFACEs: AN OPTICALLY TRANSPARENT NANOPAPER-BASED DEVICE FOR CELL CULTURE Siwan Park1, Binbin Ying1,2, Edmond W.K. Young1, and Xinyu Liu1 1University of Toronto, CANADA and 2McGill University, CANADA

Th8-818.b VISCOELASTIC FOCUSING OF PARTICLES IN TRIANGULAR MICROCHANNEL Prithviraj Mukherjee, Jian Zhou, and Ian Papautsky University of Illinois, Chicago, USA

b - Micro- and Nanoengineering Nanoscale Fabrication, Patterning, and Integration M1-120.b POLYMER-BASED NANOFLUIDIC DEVICES FOR RESISTIVE-PULSE SENSING OF HEPATITIS B VIRUS CAPSIDS Sheng-Yuan Huang, Mi Zhang, Zhongchao Zhao, Adam Zlotnick, and Stephen C. Jacobson Indiana University, USA

M2-220.b APTAMER-BASED NANOFLUIDICS FOR THE MOLECULAR DETECTION IN ULTRA-SMALL VOLUME Jinbin Yang1, Hiroki Kamai1, Yong Wang2, and Yan Xu1,3 1Osaka Prefecture University, JAPAN, 2Pennsylvania State University, USA, and 3Japan Science and Technology Agency (JST), JAPAN

M2-221.b SURFACE PATTERNING OF NANOFLUIDIC CHANNELS AND ITS EVALUATION USING STREAMING CURRENT Kyojiro Morikawa1, Haruki Kazumi1, Ryoichi Ohta1, and Takehiko Kitamori1,2 University of Tokyo, JAPAN and 2National Tsing Hua University, TAIWAN

T3-319.b COATING MOFs ON MAMMALIAN CELL FOR BIOMEDICAL APPLICATIONS Laura Ha and Dong-Pyo Kim Pohang University of Science and Technology (POSTECH), KOREA

T3-320.b SELECTIVE ELECTRICAL SWITCHING OF MOLECULAR MOTORS BY DYNAMIC VIRTUAL CATHODE Kenta Hatazawa1, Ryuzo Kawamura2, and Takayuki Hoshino1 1Hirosaki University, JAPAN and 2Saitama University, JAPAN

T4-419.b DEVELOPMENT OF FABRICATION METHOD FOR CONCENTRIC CONNECTION OF MICROCHANNEL AND NANOCHANNEL Kyojiro Morikawa1, Erina Takeuchi1, and Takehiko Kitamori1,2 1University of Tokyo, JAPAN and 2National Tsing Hua University, TAIWAN

T4-420.b TECHNOLOGICAL ASPECTS OF DEVICES FOR EFFICIENT ION CONCENTRATION POLARIZATION AND ELECTRODRIVENSEPARATION WITH ULTRA-SHALLOW NANOCHANNELS Elizaveta Vereshchagina1, Yuliya Shakalisava2, Aina Suphellen1, Sigurd Moe1, and Thomas Hankemeier2 1SINTEF, NORWAY and 2Leiden University, THE NETHERLANDS

W5-519.b FABRICATION OF SUB-40-NANOMETER NANO-IN-NANO STRUCTURES IN NANOCHANNELS Hiroki Kamai1 and Yan Xu1,2 1Osaka Prefecture University, JAPAN and 2Japan Science and Technology Agency (JST), JAPAN

W5-520.b TWO-PHOTON POLYMERIZATION OF MASTERS FOR POLYMERIC NANOPILLAR REPLICATION Niamh Geoghegan1,2, Colm Delaney1, Larisa Florea3, Mark O' Loughlin1, and Susan M. Kelleher1,2 1University College Dublin, IRELAND, 2National University of Ireland, Galway, IRELAND, and 3Trinity College Dublin, IRELAND

W6-619.b INTEGRATION OF GLASS DEFORMATION NANOCHANNEL OPEN/CLOSE VALVES INTO A NANOFLUIDIC DEVICE AND FEMTO-LITER FLUID OPERATIONS Hiroki Sano1, Yutaka Kazoe2, Kyojiro Morikawa1, and Takehiko Kitamori1,3 1University of Tokyo, JAPAN, 2Keio University, JAPAN, and 3National Tsing Hua University, TAIWAN

Th7-719.b NANOFLUIDIC DEVICE WITH fL-pL DROPLET HANDLING FOR SINGLE MOLECULE CHEMICAL REACTION Naoya Sawahata1, Kyojiro Morikawa1, and Takehiko Kitamori1,2 1University of Tokyo, JAPAN and 2National Tsing Hua University, TAIWAN

Th8-819.b NANOSURFACE MICROFLUIDIC DEVICE EMBEDDED WITH NANO-TRIANGLES FOR SURFACE-ENHANCED RAMAN SPECTROSCOPY AND SURFACE-ENHANCED FLUORESCENT MICROSCOPY Mahsa Jalali, Sayed Imman Issac Hosseini, Tamer Abdelfattah, Lara Montermini, Sebastian Wachsmann Hugo, Janusz Rak, and Sara Mahshid McGill University, CANADA

b - Micro- and Nanoengineering Micropumps, Valves, and Dispensers M1-121.b A MODULAR MICROFLUIDIC PARALLEL DISPENSING SYSTEM Dean de Boer, Anke R. Vollertsen, Albert van den Berg, Andries D. van der Meer, and Mathieu Odijk University of Twente, THE NETHERLANDS

M2-222.b AUTOMATED BLOOD PLASMA SEPARATION AND METERING FOR CLINICAL SETTINGS AND CENTRIFUGAL MICROFLUIDICS DEVICES Noa Lapins, Amin Kazemzadeh, and Aman Russom KTH Royal Institute of Technology, SWEDEN

T3-321.b AUTONOMOUS CAPILLARY MICROFLUIDIC DEVICES WITH CONSTANT FLOW RATE AND TEMPERATURE-CONTROLLED VALVING Lanhui Li1,2, Eiko Westerbeek1, Jeroen Vollenbroek1,3, Lingling Shui2, Mathieu Odijk1, and Jan Eijkel1 1University of Twente, THE NETHERLANDS, 2South China Normal University, CHINA, and 3University Medical Center, THE NETHERLANDS

T4-421.b BARRIER-FILM BASED REAGENT STORAGE AND RELEASE ON MICROFLUIDIC PLATFORMS FOR SAMPLE-TO-ANSWER AUTOMATION OF BIOASSAYS Rohit Mishra, Darren McAuley, Natalia Rolinska, David Boyle, and Jens Ducrée Dublin City University, IRELAND

W5-521.b DEVELOPMENT OF A MIST-BASED HYDROGEL CROSSLINKING PRINTHEAD FOR DROPLET-BASED BIOPRINTING Ben MacCallum, Sara Badr, Emad Naseri, Armin Bodaghkhani, and Ali Ahmadi University of Prince Edward Island, CANADA

W6-620.b 3D-PRINTED PERISTALTIC PUMP KIT Terry Ching1,2, Yi-Chin Toh2,3, and Michinao Hashimoto1 1Singapore University of Technology and Design, SINGAPORE, 2National University of Singapore, SINGAPORE, and 3Queensland University of Technology, AUSTRALIA

W6-621.b METACHRONAL ACTUATION OF MAGNETIC ARTIFICIAL CILIA GENERATES STRONG MICROFLUIDIC PUMPING Shuaizhong Zhang, Zhiwei Cui, Ye Wang, and Jaap den Toonder Eindhoven University of Technology, THE NETHERLANDS

Th7-720.b A MICRO-MACHINED HYDRAULIC FLOW AND COMPLIANCE TUNER Cornelia Nef1, Peter Heeb2, Sabrina Frey3, Dominic Obrist4, and André Bernard5 1OST University of Applied Science, SWITZERLAND, 2FISBA AG, SWITZERLAND, 3CorFlow Therapeutics AG, SWITZERLAND, 4University of Bern, SWITZERLAND, 5matriq AG, SWITZERLAND

Th7-721.b RECIPROCATING FLOW-ASSISTED FINGER-ACTUATED DNA EXTRACTION DEVICE Dong Hyun Han, Juhwan Park, and Je-Kyun Park Korea Advanced Institute of Science and Technology (KAIST), KOREA

Th8-820.b A MICROFLUIDIC VALVING ARRAY FOR WEARABLE BIOFLUID MANAGEMENT Jiawei Tan, Haisong Lin, Shuyu Lin, Wenzhuo Yu, Jialun Zhu, Yichao Zhao, Xuanbing Cheng, Siyang Yang, Eric Tang, and Sam Emaminejad University of California, Los Angeles, USA

Th8-821.b ROTARY ACTUATION SYSTEM FOR MAGNETIC BEADS Fujio Tsumori and Kazuki Tokumaru Kyushu University, JAPAN

b - Micro- and Nanoengineering Bonding, Sealing & Interfacing Technologies M1-122.b DIRECT LASER WRITING IN THERMOPLASTIC MICROCHANNELS BY IN SITU PHOTOINITIATION Jung Y. Han, Sarah Warshawsky, and Don L. DeVoe University of Maryland, College Park, USA

M2-223.b SIMULATION OF TUMOR CELL EXTRAVASATION ON A PHOTOLITHOGRAPHY-FREE MICROFLUIDIC DEVICE Yuichiro Asaumi1 and Naoki Sasaki1,2 1Toyo University, JAPAN and 2Rikkyo University, JAPAN

b - Micro- and Nanoengineering New Materials and Surface Modification M1-123.b MECHANISTIC STUDY OF OXYGEN-SCAVENGING PROPERTIES OF OFF-STOICHIOMETRIC THIOL-ENES Iiro Kiiski1, Päivi Järvinen1, Ville Jokinen2, and Tiina Sikanen1 1University of Helsinki, FINLAND and 2Aalto University, FINLAND

M2-224.b MULTI-MODAL ANALYSIS OF TUMOR-DERIVED EXTRACELLULAR VESICLES IMMUNOCAPTURED FROM PLASMA Pepijn Beekman1, Agustin Enciso-Martinez2, Melissa Piontek3, Leon Terstappen2, Wouter Roos3, Cees Otto2, and Séverine Le Gac1 1University of Twente, THE NETHERLANDS and 2Rijksuniversiteit Groningen, THE NETHERLANDS

T3-322.b DEVELOPMENT OF A FLOW-FREE GRADIENT GENERATOR USING A SELF-ADHESIVE THIOL-ACRYLATE MICROFLUIDIC RESIN/HYDROGEL (TAMR/H) HYBRID SYSTEM Anowar H. Khan1, Noah M. Smith1, Michael P. Tullier1, B. Seth Roberts1, Derek Englert2, John A. Pojman1, and Adam T. Melvin1 1Louisiana State University, USA and 2University of Kentucky, USA

T3-323.b NANOCATALYSTS FOR MAGNETIC FILED ASSISTED BIOFILM ERADICATION Mamata Karmacharya1,2, Sumit Kumar1,2, and Yoon-Kyoung Cho1,2 1Ulsan National Institute of Science & Technology (UNIST), KOREA and 2Institute for Basic Science (IBS), KOREA

T4-422.b ELECTROACTIVE POLYMER MEMBRANES AS SUBSTRATES FOR POINT-OF-CARE DEVICES Ricardo Brito-Pereira1, André S. Macedo1, Senentxu Lanceros-Méndez1,2,3, and Vanessa F. Cardoso1 1University of Minho, PORTUGAL, 2BCMaterials, SPAIN, and 3IKERBASQUE, Basque Foundation for Science, SPAIN

W5-522.b EVALUATION OF MINERAL AND BACTERIA ADHESION ON MICROCHANNEL COATED WITH DIAMOND LIKE CARBON AND MPC BASED COPOLYMER Tomomi Sato, Shun Murooka, Toshihiro Kasama, Zhou Lu, Madoka Takai, and Ryo Miyake University of Tokyo, JAPAN

W6-622.b FABRICATION OF GOLD-NANORINGS FOR MASSIVELY PARALLEL INTRACELLULAR DELIVERY Loganathan Mohan1, Ren Hattori1, Miho Ishii-Teshima1, Sathish Sundar Dhilip Kumar2, Srabani Kar3, Tuhin Subhra Santra4, Takayuki Shibata1, and Moeto Nagai1 1Toyohashi University of Technology, JAPAN, 2University of Johannesburg, SOUTH AFRICA, 3University of Cambridge, UK, and 4Indian Institute of Technology Madras, INDIA

Th7-722.b HOLIFAB: PRECISE FLOW CONTROL USING PHOTO ACTUATED HYDROGEL VALVES AND PI CONTROLLED LED ACTUATION FOR MICROFLUIDIC MEMS. Ruairí Barrett, Komala Pandurangan, Akshay Shinde, Dermot Diamond, and Margaret McCaul Dublin City University, IRELAND

Th8-822.b MECHANICAL CHARACTERIZATION OF SPIDER SILK NANOMEMBRANES Linnea Gustafsson, Christos Panagiotis Tasiopoulos, Thijs Duursma, Ronnie Jansson, Thomas Christian Gasser, My Hedhammar, and Wouter van der Wijngaart KTH Royal Institute of Technology, SWEDEN

b - Micro- and Nanoengineering Others T4-423.b RECONSTITUTION OF HUMAN PRIMORDIAL GERM CELL DEVELOPMENT FROM PLURIPOTENT STEM CELLS IN A SYNTHETIC EMBRYONIC ENVIRONMENT Sajedeh Nasr Esfahani1, Yi Zheng1, Agnes M. Resto Irizarry1, Yue Shao2, Sicong Wang1, Xufeng Xue1, and Jianping Fu1 1University of Michigan, Ann Arbor, USA and 2Tsinghua University, CHINA

b - Micro- and Nanoengineering Industrial Benefactor M1-124.b FROM LAB TO FAB: CONSIDERATIONS FOR DEVICE DESIGN AND MANUFACTURING OPTIONS FOR UPSCALING MICROFLUIDIC DEVICE PRODUCTION Holger Becker, Nadine Hlawatsch, Richard Klemm, and Claudia Gärtner microfluidic ChipShop GmbH, GERMANY

M2-282.b Hicomp - YOUR TRUSTED TECHNOLOGY AND SOLUTION PROVIDER FOR MICROFLUIDICS Yexiam Wu HiComp Microtech (Suzhou) Co., Ltd., CHINA

Th7-783.b MASKLESS ALIGNER TECHNOLOGY FOR THICK PHOTORESIST APPLICATIONS Gregg Moore and Niels Wijnaendts van Resandt Heidelberg Instruments, Inc., USA

b - Micro- and Nanoengineering Late News M1-174.b CELLOPHANE-BASED ANALYTICAL DEVICES FOR PUMP-FREE LIQUID TRANSPORT AND BACKGROUND-TINTED COLORIMETRIC ASSAYS Hiroki Shigemori, Kento Maejima, Hiroyuki Shibata, Yuki Hiruta, and Daniel Citterio Keio University, JAPAN

M1-175.b ON-CHIP BIDIRECTIONAL MICROFLUIDIC PUMPING ACTUATED REMOTELY BY ACOUSTIC WAVES Tao Luo and Mingming Wu Cornell University, USAch

M1-176.b REVERSIBLE UNDERWATER-ADHESIVE HYDROGEL MICROSTRUCTURE BASED ON PHOTOCROSSLINKING GRADIENT Jinsik Yoon and Wook Park Kyung Hee University, KOREA

M2-274.b DEMOCRATISED MICROFLUIDIC PROTOTYPING USING A 3D-PRINTED CLICK-AND- CONNECT SCAFFOLD LIBRARY Robert R. Hughes, Harry Felton, and Andrea Diaz Gaxiola University of Bristol, UK

M2-275.b OPTICAL METHOD FOR THE MEASUREMENT OF TRANSIENT FLOW RATES OF A TPU- MEMBRANE-BASED MICROPUMP Hannah Bott1, Ronny Leonhardt1, Franz Laermer1, Roland Zengerle2, and Jochen Hoffmann1 1Robert Bosch GmbH, GERMANY and 2University of Freiburg, GERMANY

M2-276.b SIMPLE METHOD FOR MICRO-PATTERNED CONDUCTIVE HYDROGEL FABRICATION Hyeli Kim, Goomin Kwon, Jungmok You, and Wook Park Kyung Hee University, KOREA

T3-375.b DESIGN AND MICROFABRICATION OF MICROREACTOR ARRAY FOR PLATE READER FOR E. Coli RESEARCH Gaozhe Cai1,2, Shilun Feng1, Yang Liu1, Wenshuai Wu1, Jingbo Zhang1, Jianhan Lin2, and Ai-Qun Liu1 1Nanyang Technological University, SINGAPORE and 2China Agricultural University, CHINA

T3-376.b STUDY OF THE FABRICATION OF MODULAR FLUIDIC/MICROFLUIDIC PLATFORM USING A LOW-CLASS 3D PRINTER Isa Anshori1, Vincent Lukito1, Angelica Irene1, Brian Yuliarto1, and Briliant Adhi Prabowo2 1Institut Teknologi Bandung, INDONESIA and 2International Iberian Nanotechnology Laboratory, PORTUGAL

T4-475.b DEVELOPMENT OF A MICRO-MICROBIAL DOMESTICATION POD FOR IN-SITU MARINE BACTERIAL CULTIVATION Sydney K. Wheatley1, Christopher Cartmell1, Bradley A. Haltli1,2, Russell G. Kerr1,2, and Ali Ahmadi1 1University of Prince Edward Island, CANADA and 2Nautilus Biosciences, CANADA

T4-476.b THROMBOGENIC POLYMER SURFACE MANIPULATION OF MICROFLUIDIC CHIPS VIA ULTRAVIOLET LASER Yi Xu1, Guang Yu1, Ruqiong Nie2, and Zhigang Wu1 1Huazhong University of Science and Technology, CHINA and 2Sun Yat-Sen University, CHINA

W5-574.b DUAL-SCALE PERMANENT MAGNET FOR ENHANCED MAGNETIC SORTING EFFICIENCY IN A MICROFLUIDIC SYSTEM Lucie Descamps1, Samir Mekkaoui1, Marie-Charlotte Audry1, Emmanuelle Laurenceau1, Jessica Garcia1, Léa Payen2, Anne-Laure Deman1, and Damien Le Roy2 1Université Lyon 1, FRANCE and 2Hospices Civils de Lyon, FRANCE W5-575.b TRAFFIC-LIGHT-TYPE MICROFLUIDIC PAPER-BASED ANALITICAL DEVICE FOR HYDROGEN PEROXIDE DETECTION Sera Ohta, Ryuya Hiraoka, Yuki Hiruta, and Daniel Citterio Keio University, JAPAN

W6-675.b ACTIVE AND PASSIVE FLOW CONTROL BY PNEUMATIC ACTUATED FLEXIBLE VALVE ON SINGLE LAYER Yoshiharu Bessho, Yingzhe Wang, and Keisuke Morishima Osaka University, JAPAN

W6-676.b FABRICATION OF A MICROPARTICLE COATED WITH A GOLD NANO THIN FILM Kibeom Kim and Wook Park Kyung Hee University, KOREA

Th7-774.b BATTERY-FREE BUILT-IN MICROPUMP DRIVEN BY A SELF-PROPELLED DROPLET Taiji Okano1, Kazuki Otsubo2, Junya Wada2, and Hiroaki Suzuki2 1Tokyo University of Agriculture and Technology, JAPAN and 2Chuo University, JAPAN

Th7-775.b HYDROGEL-BASED Microswimmer MOVING TOWARDS THE TARGET POSITION WITH RECOGNITION OF ENVIRONMENTAL CHANGES Cheolheon Park1, Youngjae Choi2, Sunghoon Kwon2, and Wook Park1 1Kyung Hee University, KOREA and 2Seoul National University, KOREA

Th8-872.b FULLY AUTOMATED IMMUNOASSAY IN A LAB-ON-A-FOIL DEVICE WITH LED-ACTUATED VALVES Mireia Burdó-Masferrer1, María Díaz-González1, Ana Sanchis2,3, M.-Pilar Marco2,3, César Fernández-Sánchez1,3, and Antonio Baldi1 1Institut de Microelectrònica de Barcelona, SPAIN, 2Institut de Química Avançada de Catalunya, SPAIN, and 3CIBER-BBN, SPAIN

Th8-873.b INK-JET PRINTED MICROFLUIDIC PAPER-BASED ANALYTICAL DEVICES RELYING ON QR CODE DETECTION Aya Katoh, Kento Maejima, Yuki Hiruta, and Daniel Citterio Keio University, JAPAN

c - Sensors and Detection Technologies Physical Sensors M1-125.c HARDNESS MEASUREMENT BY MICROMANIPULATOR WITH EMBEDED SEMICONDUDTOR STRAIN GAUGE Mitsuhiro Horade National Defense Academy of Japan, JAPAN

M2-225.c LOVE WAVE SENSOR FOR DETECTION OF VISCOSITY CHANGES ON A CELL MONOLAYER Pedro A. Segura Chavez1,2, Frederic Sarry1,2, Mohamed Lamine Fayçal Bellaredj2, Jérémy Bonhomme1,2, Lucile Olive2, Denis Beyssen2, Mourad Oudich2, and Paul G. Charette1 1Universite de Sherbrooke, CANADA and 2Universite de Lorraine, FRANCE

T3-324.c DEVELOPMENT OF A QCM-P SENSING SYSTEM FOR BIOLOGICAL DETECTION Siqi Ji1, Berk Akinci2, Tory A. Farnping3, Thomas A. Radzik3, and Hongwei Sun1 1University of Massachusetts, Lowell, USA, 2Invitrometrix, USA, and 3Lowell High School, USA

T4-424.c WEARABLE MICROFLUIDIC SENSOR TO MONITOR SWEAT FLOW RATE AND ELECTROLYTE CONCENTRATION Yuki Hashimoto1, Yuki Sakurai1,2, Takako Ishihara1, Kei Kuwabara1, and Hiroyoshi Togo1 1NTT Device Innovation Center, NTT Corporation, JAPAN and 2Nagaoka University of Technology, JAPAN W5-523.c A FLEXIBLE AND STABLE STRAIN SENSOR BASED ON POLYIMIDE INCORPORATED WITH CARBON BLACK Jie Wang, Yunfei Liu, Wenhan Chang, Shoule Sun, Chengchen Gao, Zhenchuan Yang, and Yilong Hao Peking University, CHINA

W6-623.c CARBON NANOTUBE-PAPER COMPOSITE-CAPACITIVE SENSOR FOR RESPIRATORY MONITORING Tianyi Li, Vigneshwar Sakthivelpathi, Seong-Joong Kahng, Zhongjie Qian, Sheila Goodman, Heather Wise, Anthony B. Dichiara, Younghoon Kwon, and Jae-Hyun Chung University of Washington, USA

Th7-723.c A COMPACT MICROCALORIMETER FOR THE RAPID CHARACTERIZATION OF LIQUID THERMAL PROPERTIES Sheng Ni1, Hanliang Zhu2, Pavel Neuzil2,3, and Levent Yobas1 1Hong Kong University of Science and Technology, HONG KONG, 2Northwestern Polytechnical University, CHINA, and 3Brno University of Technology, CZECH REPUBLIC

Th8-823.c DESIGN AND CONSTRUCTION OF A CONTINUOUS QUANTITATIVE FORCE MEASUREMENT MICRODEVICE FOR ARTIFICIAL SKELETAL MUSCLE Masaki Harada, Tomohiro Nakamura, and Sho Yokoyama Osaka Institute of Technology, JAPAN

c - Sensors and Detection Technologies Chemical & Electrochemical Sensors M1-126.c A PAPER-BASED DEVICE FOR INTEGRATED HIGH-THROUGHPUT COVID-19 DETECTION Hao Sun1,2, Jianping Zheng3, Hui Dong1,2, and Yuan Jia4 1Fuzhou University, CHINA, 2Fujian Provincial Collaborative Innovation Center of High-End Equipment Manufacturing, CHINA, 3Fujian Provincial Hospital, CHINA, and 4Southeast University, CHINA

M1-127.c ELECTROCHEMICAL OLIGONUCLEOTIDE TEMPLATED REACTIONS Robert B. Channon1, Philip Gillespie1, Md Nazmul Islam2, Xiaotong Meng1, Yu-Chih Chen1, Danny O'Hare1, and Sylvain Ladame1 1Imperial College London, UK and 2Teeside University, UK

M1-128.c MULTISTEP REACTIONS BY ALIGNED TABLET REAGENTS FOR LONG TERM MONITORING OF PLANT CULTURE SOLUTION Yoko Azuma1,4, Toshihiro Kasama1,4, Yoshishige Endo1,4, Tetsushi Koide2,4, Chiharu Sone3,4, Masashi Komine3,4, Atsushi Ogawa3,4, and Ryo Miyake1,4 1University of Tokyo, JAPAN, 2Hiroshima University, JAPAN, 3Akita Prefectural University, JAPAN, and 4Japan Science and Technology Agency (JST), JAPAN

M1-129.c PRINTED MULTISENSING PATCH WITH INTEGRATED MICROFLUDICS FOR WEARABLE SWEAT ANALYSIS APPLICATIONS Brince Paul1, Silvia Demuru1, Rubaiyet Iftekharul Haque1, Peter van der Wal1, Céline Lafaye2, Mathieu Saubade2, and Danick Briand1 1École Polytechnique Fédérale de Lausanne (EPFL), SWITZERLAND and 2Centre Hospitalier Universitaire Vaudois (CHUV), SWITZERLAND

M2-226.c A THREAD-BASED ELECTROCHEMICAL SENSOR FOR SPATIAL MONITORING OF WOUND OXYGENATION Junfei Xia, Wenxin Zeng, Wei Wang, Rachel Owyeung, Victor Arsenescu, and Sameer Sonkusale Tufts University, USA

M2-227.c ELECTROCHEMICAL SENSOR FOR Mn DETECTION IN DRINKING WATER Elena Boselli1, Zhizhen Wu1, Alexa Friedman2, Birgit Claus Henn2, and Ian Papautsky1 1University of Illinois, Chicago, USA and 2Boston University School of Public Health, USA

M2-228.c NANOPORE DECODING FOR DNA COMPUTATION WITH PARALLEL SELF-ASSEMBLY Sotaro Takiguchi and Ryuji Kawano Tokyo University of Agriculture and Technology, JAPAN

M2-229.c TiO2 NANOTUBES-HYDROGEL BIOSENSOR SCAFFOLD FOR SWEAT MONITORING Udara B. Gunatilake1, Edilberto Ojeda1, Sandra Garcia-Rey1, Lourdes Basabe-Desmonts1,2, and Fernando Benito-Lopez1 1University of the Basque Country, SPAIN and 2Basque Foundation of Science, IKERBASQUE, SPAIN

T3-325.c ANALYSIS OF ION COMPONENTS DERIVED FROM PARTICULATE MATTER USING ION SELECTIVE ELECTRODES Haruka Yamauchi1, Taisuke Shimada1, Takao Yasui1,2, Tatsuro Goda3, Noritada Kaji4, Yuji Miyahara3, and Yoshinobu Baba1,5 1Nagoya University, JAPAN, 2Japan Science and Technology Agency (JST), JAPAN, 3Tokyo Medical and Dental University, JAPAN, 4Kyushu University, JAPAN, 5National Institutes for Quantum and Radiological Science and Technology, JAPAN

T3-326.c EMBEDDED SENSOR BASED ON TANDEM SMARTPHONE-MICROFLUIDIC DEVICE FOR THE DETECTION OF TNT IN SURFACE AND SEA WATERS Jérémy Bell, Mustafa Biyikal, and Knut Rurack Bundesanstalt für Materialforschung & -prüfung (BAM), GERMANY

T3-327.c NOVEL FORMAT OF A PAPER-BASED DEVICE FOR COMPETITIVE IMMUNOASSAYS Takeshi Komatsu, Masatoshi Maeki, Akihiko Ishida, Hirofumi Tani, and Manabu Tokeshi Hokkaido University, JAPAN

T3-328.c TOWARDS ON-SITE MONITORING OF SOIL NUTRIENTS VIA CAFETIERE-BASED EXTRACTION AND PAPER-BASED ANALYSIS Samantha Richardson1, Samira AlHinai1, Jesse Gitaka2, Will M. Mayes1, Mark Lorch1, and Nicole Pamme1 1University of Hull, UK and 2Mount Kenya University, KENYA

T4-425.c ANALYSIS OF PARTICULATE MATTERS VIA SURFACTANT-ASSISTED IONIC CURRENT SENSING Keiko Fujino1, Taisuke Shimada1, Takao Yasui1,2, Kazuki Nagashima3, Takashi Yanagida3, Noritada Kaji3, and Yoshinobu Baba1,4 1Nagoya University, JAPAN, 2Japan Science and Technology Agency (JST), JAPAN, 3Kyushu University, JAPAN, and 4National Institutes for Quantum and Radiological Science and Technology, JAPAN

T4-426.c HIGH-RESOLUTION BIOCHEMICAL ACTIVITY MEASUREMENTS WITH COMMERCIAL TRANSISTORS Seulki Cho, Son T. Le, Curt A. Richter, and Arvind Balijepalli National Institute of Standards and Technology (NIST), USA

T4-427.c ON-CHIP MONITORING OF PHOSPHATE VIA A DROPLET MICROFLUIDIC SENSOR Bingyuan Lu1, Sharon Coleman1, Evanthia Papadopoulou2, Kyriacos Makris2, Brett M. Warren2, Adrian M. Nightingale1, and Xize Niu1 1University of Southampton, UK and 2SouthWestSensor Ltd., UK

T4-428.c WEARABLE PATCH-TYPE DEVICE FOR BIO-INFORMATION MONITORING WITH POROUS MICRONEEDLE AND FLEXIBLE AG/AGCL REFERENCE ELECTRODE Ryohei Takizawa, Yuina Abe, Bibek Raut, Hajime Konno, Natsumi Kimura, Shotaro Yoshida, Hiroya Abe, and Matsuhiko Nishizawa Tohoku University, JAPAN W5-524.c A BIOCHIP INTEGRATED WITH MICROELECTRODES FOR MONITORING OF PYOCYANIN IN THE FORMATION PROCESS OF BIOFILMS Lulu Liu, Ling Li, Chuang Ge, and Yi Xu Chongqing University, CHINA

W5-525.c CARBON DOT-CONJUGATED-NAPHTHALIMIDE BASED RATIOMETRIC FLUORESCENCE PROBE FOR HYALURONIDASE DETECTION Pushap Raj and Tae Yoon Lee Chungnam National University, KOREA

W5-526.c HYBRID WEARABLE TECHNOLOGY FOR SWEAT BIOMONITORING Meritxell Rovira1, César Fernández-Sánchez1, Silvia Demuru2, Rubaiyet Haque2, Danick Briand2, and Cecilia Jimenez-Jorquera1 1Instituto de Microelectrónica de Barcelona (IMB-CNM), SPAIN and 2École Polytechnique Fédérale de Lausanne (EPFL), SWITZERLAND

W5-527.c OPEN CHANNEL SWEAT VIA FOR LONG-TERM MONITORING OF SWEAT RATE AND CONCENTRATION Jina Choi1, Sangha Kim1, Sunho Kim2, Hyunjung Yi2, and Rhokyun Kwak1 1Hanyang University, KOREA and 2Korea Institute of Science and Technology (KIST), KOREA

W6-624.c A DIFFERENTIAL MODE EXTENDED GATE FIELD EFFECT TRANSISTOR PH SENSOR BASED ON AL2O3 THICKNESS DEPENDENT SENSITIVITY Qi Cheng, Qiancheng Zhao, Chengchen Gao, Yilong Hao, and Zhenchuan Yang Peking University, CHINA

W6-625.c DIFFERENTIAL PHOTOELECTROCHEMICAL DNA SENSING BY MODULATING THE PLASMONIC PROPERTIES OF METAL NANOPARTICLES Sudip Saha, Amanda Victorious, and Leyla Soleymani McMaster University, CANADA

W6-626.c HYDROGEL-BASED TRANSPARENT SUBDURAL ELECTRODE WITH IONIC CONNECTION Ayaka Nishimura, Ryota Suwabe, Yuka Ogihara, Yuina Abe, Hiroya Abe, Shotaro Yoshida, and Matsuhiko Nishizawa Tohoku University, JAPAN

W6-627.c OXYGEN METABOLISM ANALYSIS OF A VASCULARIZED SPHEROID USING A SCANNING ELECTROCHEMICAL MICROSCOPY Yuji Nashimoto1, Rei Mukomoto1, Takato Terai1, Kosuke Ino1, Koichi Nishiyama2, Ryuji Yokokawa3, Takahsi Miura4, and Hitoshi Shiku1 1Tohoku University, JAPAN, 2Kumamoto University, JAPAN, 3Kyoto University, JAPAN, and 4Kyushu University, JAPAN

Th7-724.c A DUAL-READOUT PAPER-BASED SENSOR FOR ON-SITE DETECTION OF PENICILLINASE WITH A SMARTPHONE Jia Xu and Li Yang Northeast Normal University, CHINA

Th7-725.c EFFECT OF MEMBRANE ELECTRODE VIBRATION ON MASS TRANSFER FOR ELECTROCHEMICAL MICRO SENSORS Tianyi Zhang, Peng Zhou, Terrence Simon, and Tianhong Cui University of Minnesota, USA

Th7-726.c LABEL-FREE IMPEDIMETRIC SENSING OF CORTISOL IN HUMAN SERUM BASED ON NANOWELL ARRAY ELECTRODES Seyed Reza Mahmoodi1, Pengfei Xie1, Daniel P. Zachs2, Erik J. Peterson2, Hubert H. Lim2, Mark Allen3, and Mehdi Javanmard1 1Rutgers University, USA, 2University of Minnesota, USA, and 3University of Pennsylvania, USA

Th7-727.c POINT-OF-CARE MICROANALYZER FOR POTENTIOMETRIC DETERMINATION OF AMMONIUM IN PLASMA Beatriz Rebollo-Calderon1, Antonio Calvo-Lopez1, Aida Ormazabal2, Mar Puyol1, Rafael Artuch2, and Julian Alonso-Chamarro1 1Autonomous University of Barcelona, SPAIN and 2Sant Joan de Déu Hospital, SPAIN

Th8-824.c A NON-ENZYMATIC ELECTROCHEMICAL SENSOR USING WRINKLED GOLD FILM ON SHRINK POLYMER Xiaomeng Bian1 and Tianhong Cui2 1Tsinghua University, CHINA and 2University of Minnesota, USA

Th8-825.c ELECTROCHEMICAL DETERMINATION OF MANGANESE IN WHOLE BLOOD Zhizhen Wu and Ian Papautsky University of Illinois, Chicago, USA

Th8-826.c MULTIPLEX SENSOR FOR ION SENSING BASED ON PRINTED CIRCUIT BOARD Zhehao Zhang and Ian Papautsky University of Illinois, Chicago, USA

Th8-827.c POWER-FREE AUTOMATED CAPILLARY FLOW ASSAY FOR SARS-COV-2 DETECTION Jeremy Link1, Cody Carrell1, Ilhoon Jang1,2, Yosita Panraksa1,3, Ana Sánchez-Cano1,4, Zachary Call1, Eka Noviana1, David S. Dandy1, Brian J. Geiss1, and Charles S. Henry1 1Colorado State University, USA, 2Hanyang University, KOREA, 3Chulalongkorn University, THAILAND, and 4Universitat Autònoma de Barcelona (UAB), SPAIN

c - Sensors and Detection Technologies Optical Sensors & Imaging M1-130.c DNA SEQENCING USING RGB SENSOR OF COMSUMER DIGITAL CAMERA Takashi Anazawa1, Motohiro Yamazaki2, Shuhei Yamamoto2, and Ryoji Inaba2 1Hitachi, Ltd., JAPAN and 2Hitachi High-Tech Corporation, JAPAN

M1-131.c REAL-TIME STRAIN MEASUREMENT OF PIEZOELECTRICALLY ACTUATED POLYDIMETHYLSILOXANE (PDMS) BAR USING FIBRE BRAGG GRATING SENSOR FOR BIOMEDICAL APPLICATIONS Rahul Kumar1, Bruno Rente1, Souvik Ghosh1, Christabel Tan2, Tong Sun1, and Kenneth Grattan1 1City University of London, UK and 2University of Hertfordshire, UK

M2-230.c REAL-TIME TRACKING OF PARTICLES AT >1,200 EVENTS PER SECOND USING GPU- ACCELERATED IMAGE PROCESSING Arpith Vedhanayagam and Amar S. Basu Wayne State University, USA

T3-329.c FABRICATION AND CHARACTERIZATION OF AXIAL VIEW LIQUID ELECTRODE PLASMA Yueh-Han Huang1, Daisuke Hirose2, Meng-Jiy Wang1, and Yuzuru Takamura2 1National Taiwan University of Science and Technology, TAIWAN and 2Japan Advanced Institute of Science and Technology, JAPAN

T3-330.c REFERENCE PH MICROSENSR FOR FLUORESCENCE MEASUREMENT IN CELL CULTURE ENVIRONMENT WITHOUT INITIAL PH INFORMATION Hisataka Maruyama1 and Fumihito Arai2 1Nagoya University, JAPAN and 2University of Tokyo, JAPAN

T4-429.c HIGH RESOLUTION PATTERNING OF HYDROGEL SENSING MOTIFS WITHIN FIBROUS SUBSTRATES FOR HIGHLY SENSITIVE AND MULTIPLEXED DETECTION OF NUCLEIC ACID BIOMARKERS Dana Al Sulaiman, Sarah J. Shapiro, Jose Gomez-Marquez, and Patrick S. Doyle Massachusetts Institute of Technology, USA

T4-430.c SOLVENT-ENHANCED PHOTOTHERMAL MOLECULE DETECTION METHOD FOR NANOFLUIDICS AND ITS APPLICATION TO FEMTOLITER NORMAL-PHASE CHROMATOGRAPHY Yoshiyuki Tsuyama, Kyojiro Morikawa, and Kazuma Mawatari University of Tokyo, JAPAN

W5-528.c A MODULAR SMARTPHONE-ENABLED PLATFORM TO DETECT NUCLEIC ACID TARGETS BASED ON QUANTIFICATION OF COALESCED LAMP PRECIPITATE Manaswini Masetty, Joseph Sepate, Sanghyun Do, and Aashish Priye Univeristy of Cincinnati, USA

W5-529.c INTEGRATED MICROFLUIDIC SERS CHIP FOR THE CAPTURE AND DETECTION OF PATHOGENIC BACTERIA IN THE AIR Xi Su, Rui Ren, Shifang Li, Li Chen, and Yi Xu Chongqing University, CHINA

W5-530.c SPATIOTEMPORAL MAPPING OF A HYPOXIA-FFA SYNERGY ON BETA CELL CALCIUM OSCILLATIONS Kai Duan and Joe Fujiou Lo University of Michigan, Dearborn, USA

W6-628.c ACHIEVING SUB-MICROMETER IMAGING RESOLUTION IN PDMS SOFT LITHOGRAPHY DEVICES USING MODIFIED INVERTED SELECTIVE PLANE ILLUMINATION MICROSCOPY Tienan Xu1, Yean Jin Lim1, Yujie Zheng1, Moon Sun Jung2, Katharina Gaus2, Elizabeth E. Gardiner1, and Woei Ming Lee1 1Australian National University, AUSTRALIA and 2University of New South Wales, AUSTRALIA

W6-629.c LOW-COST AND PORTABLE PHOTONIC IMMUNO-SENSOR BASED ON GUIDED MODE RESONANCE Alexander Drayton, Kezheng Li, Matthew Simmons, Christopher Reardon, and Thomas F. Krauss University of York, UK

W6-630.c ULTRASENSITIVE PLASMONIC SENSORS ON OPTICAL FIBERS END-FACE Alba Calatayud-Sanchez1, Angel Ortega-Gomez1, Javier Barroso1, Joseba Zubia1, Fernando Benito-Lopez1, Joel Villatoro1,2, and Lourdes Basabe-Desmonts1,2 1University of the Basque Country, SPAIN and 2Basque Foundation of Science, IKERBASQUE, SPAIN

Th7-728.c DETECTION OF HYDROGEN SULPHIDE IN HUMAN BLOOD PLASMA ON A MICROFLUIDIC PLATFORM Ravindra Gaikwad, Karunya Ramsamy, and Ashis K. Sen Indian Institute of Technology, Madras, INDIA

Th7-729.c METAL ION ENRICHMENT USING ORGANIC NANOCRYSTAL COATED-MICROFLUIDIC PAPER ANALYTICAL DEVICES TO ACHIEVE HIGHLY SENSITIVE COLORIMETRIC DETECTION Grasianto, Mao Fukuyama, Derrick Mott, Yoshitaka Koseki, Hitoshi Kasai, and Akihide Hibara Tohoku University, JAPAN

Th8-828.c DEVELOPMENT OF A SCANNING PIV TECHNIQUE FOR 3D CHARACTERIZATION OF FLOWS IN MICROCHANNELS Quentin Galand, Pierre Gelin, Ketki Srivastava, David Blinder, Peter Schelkens, and Wim De Malsche Vrije Universiteit Brussel, BELGIUM

Th8-829.c RAPID IDENTIFICATION OF HCC SERUM BASED ON MICROFLUIDIC SERS CHIP Xinyu He, Chuang Ge, Li Chen, and Yi Xu Chongqing University, CHINA

c - Sensors and Detection Technologies Others M1-132.c FLEXIBLE POLYOLEFIN-BASED DOPAMINE SENSOR WITH HIGH SELECTIVITY Wenzheng He1, Ruitao Liu1, Peng Zhou2, Qingyuan Liu1, Tianhong Cui2 1Tsinhua University, CHINA and 2University of Minnesota, USA

M1-133.c WIRELESS AND BATTERY-FREE DIGESTIBLE SENSOR FOR INTESTINAL BACTERIA MONITORING Ayaka Inami, Erika Iyama, Shun Itai, and Hiroaki Onoe Keio University, JAPAN

M2-231.c GRADIENT ELUTION MOVING BOUNDARY ELECTROPHORESIS OF HOMEMADE FUEL- OXIDIZER EXPLOSIVES Shannon T. Krauss1, Dillon Jobes2, and Thomas P. Forbes1 1National Institute of Standards and Technology (NIST), USA and 2Tulane University, USA

T3-331.c LOW-COST LOW-MOTION ARTIFACT ON-SKIN SENSOR-SYSTEM FOR PHYSIOLOGICAL SIGNAL RECORDING Anan Zhang, Thalia Hua, Damian Redfearn, and S.K. Ameri Queen's University, CANADA

T4-431.c PAPER MICROFLUIDICS DEVICE FOR LABEL-FREE DETECTION OF MESENCHYMAL STEM CELLS SECRETED VASCULAR ENDOTHELIAL GROWTH FACTOR Enrique Azuaje Hualde1, Marian Martínez de Pancorbo1, Fernando Benito Lopez1, and Lourdes Basabe-Desmonts1,2 1University of the Basque Country, SPAIN and 2Basque Foundation of Science, IKERBASQUE, SPAIN

W5-531.c PLGA POROUS MICRONEEDLES FOR INTERSTITIAL FLUID COLLECTION AIMED FOR CONTINUOUS GLUCOSE SENSING Gwenaël Bonfante, Hakjae Lee, Leilei Bao, Nobuyuki Takama, and Beomjoon Kim University of Tokyo, JAPAN

W6-631.c RAPID LABEL-FREE DNA QUANTIFICATION BY MULTI-FREQUENCY IMPEDANCE SENSING ON A CHIP Jianye Sui1, Neeru Gandotra2, Curt Scharfe2, and Mehdi Javanmard1 1Rutgers University, USA and 2Yale University, USA

Th7-730.c AN ULTRASENSITIVE SURFACE ACOUSTIC WAVE SENSOR BASED ON TI3C2Tx/Au NPS COMPOSITE FOR THE DETECTION OF ENDOTOXIN Xiao Li Wang, Chuang Ge, Li Chen, and Yi Xu Chongqing University, CHINA

Th7-731.c SHAKE IT OR SHRINK IT: MASS TRANSPORT AND KINETICS IN SURFACE BIOASSAYS USING AGITATION AND MICROFLUIDICS Anna Fomitcheva Khartchenko, Iago Pereiro, and Govind V. Kaigala IBM Research - Europe, SWITZERLAND

Th8-830.c DETECTION OF PROTEOFORMS FROM SINGLE CELLS BY MULTIPLEXED ION BEAM IMAGING Gabriela Lomeli1, Marc Bosse2, Sean Bendall2, Michael Angelo2, and Amy E. Herr3 1UC Berkeley – UCSF Graduate Program in Bioengineering, USA, 2University of California, Berkeley, USA, and 3Stanford University, USA

Th8-831.c STIMULI-RESPONSIVE HYDROGELS EMBEDDING MECHANICHAL METAMATERIALS FOR HIGH SENSITIVE BIOCHEMICAL SENSORS Shota Yamawaki, Mio Tsuchiya, and Hiroaki Onoe Keio University, JAPAN

c - Sensors and Detection Technologies Industrial Benefactor T3-332.c NOVEL IMAGING BASED HIGH-SPEED, HIGH-THROUGHPUT ANALYSIS AND CONTROL SYSTEM FOR MICROFLUIDICS Daniel Geiger1, Jonas Pfeil1, Tobias Neckernuss1, Lisa Kwapich2, Patricia Schwilling2, and Othmar Marti2 1Sensific GmbH, GERMANY and 2University of Ulm, GERMANY

T4-432.c FAST ELECTRICAL IMPEDANCE SPECTROSCOPY FOR CELL CHARACTERIZATION AND COUNTING Meng Li Zurich Instruments AG, SWITZERLAND

c - Sensors and Detection Technologies Late News M1-177.c PARALLELIZED FLOW CYTOMETRY REALIZED BY ARRAY OF TIME-GATED SINGLE PHOTON AVALANCHE DIODES Camille Trzeciakowski1, Daiki Sato2, Takahiro Shindo2, Takeshi Mitsunaka2, Yoshihisa Fujimoto2, Kunihiko Iizuka2, Saori Tago1, Teruo Fujii1, and Soo Hyeon Kim1,3 1University of Tokyo, JAPAN, 2Sharp Corporation, JAPAN, and 3Japan Science and Technology Agency (JST), JAPAN

M2-277.c PHOTONIC SENSOR TO DETECT OF SARS-COV-2 Binh T.T. Nguyen1, Zhenyu Li1, Yuzhi Shi1, Patricia Y. Liu1, Hongwei Zhao2, Xiaohong Zhou1, Eric P.H. Yap1, and Ai Qun Liu1 1Nanyang Technological University, SINGAPORE, 2Hainan University, CHINA, and 3Tsinghua University, CHINA

T3-377.c ELECTROCHEMICAL DNA SENSING ENHANCED BY ELECTRIC FIELD USING CRISPR- CAS12A Ziyue Li1,2, Xiong Ding1, Kun Yin1, and Changchun Liu1 1University of Connecticut Health Center, USA and 2University of Connecticut, USA

T3-378.c RAPID ANTIFUNGAL SUSCEPTIBILITY TESTING ON SILICON MICROWELLS Christopher Heuer1,2, Heidi Leonard1, Nadav Nitzan1, Ariella Lavy-Alperovitch1, Naama Massad-Ivanir1, Janina Bahnemann2, Thomas Scheper2, and Ester Segal1 1Technion - Israel Institute of Technology, ISRAEL and 2Leibniz University Hannover, GERMANY

T4-477.c AN IMPROVED ACETYLCHOLINESTERASE INHIBITION ASSAY UTILIZING ORGANIC SOLVENT EXTRACTION FOR FOOD ANALYSIS Lili Jin1, Zhenxia Hao1,2, Qingin Zheng1, Hongping Chen1,2, and Chengyin Lu1,2 1Chinese Academy of Agricultural Sciences, CHINA and 2Ministry of Agriculture and Rural Affairs, CHINA

T4-478.c FLEXIBLE DOPAMINE SENSOR WITH ELECTROPHORETIC DEPOSITED GRAPHENE OXIDE/PEDOT:PSS COMPOSITE FOR BRAIN DISORDER MONITORING Seung Hyeon Ko1,2, Seung Wook Kim2, and Yi Jae Lee1 1Korea Institute of Science and Technology (KIST), KOREA and 2Korea University, KOREA

W5-576.c ANALYSIS OF ELECTRICAL PROPERTIES OF THE CELLS USING ELECTROROTATION AND LENS-FREE IMAGE DETECTION Camila D.M. Campos1,2, Yuqian Li1, Ziduo Lin1, Geert Vanmeerbeeck1, Pawel Barmuta2,3, Tomislav Markovic1,2, Rahul Yadav1,2, Giovanni Mangraviti1, Willem Van Roy1, Ilja Ocket1, Yao Hong Liu1, Tim Stakenborg1, Richard Stahl1, Liesbet Lagae1,2, Jan Genoe1,2, and Chengxun Liu1 1Imec, BELGIUM, 2KU Leuven, BELGIUM, and 3Warsaw University of Technology, POLAND

W5-577.c MICROFLUIDIC CHIP FOR THE ELECTROCHEMICAL DETECTION OF MICRORNAs: STUDY OF THE SPECIFICITY Claire Poujouly1, Pedro Gonzalez Losada1, Sébastien Banzet2, and Jean Gamby1 1Université Paris-Saclay, FRANCE and 2Institut de Recherche Biomédicale des Armées, FRANCE

W6-677.c A MINIATURE ON-CHIP MICROSCOPE Ekta Prajapati and Shishir Kumar Indian Institute of Technology, Hyderabad, INDIA

Th7-776.c CAN WE MAKE POROUS SILICON BIOSENSORS MORE SENSITIVE? MODELING AND LIMITATIONS Sofia Arshavsky-Graham1,2, Evgeniy Boyko1, Rachel Salama1, and Ester Segal1 Technion-Israel Institute of Technology, ISRAEL

Th8-874.c INTEGRATION OF PLASMONICS AND ELECTRONICS FOR DYNAMIC TRAPPING AND SENSING OF BIOMOLECULES Daehan Yoo1, Avijit Barik1, Fernando de Léon-Pérez2,3, Daniel A. Mohr1, Matthew Pelton4, Luis Martín-Moreno3, and Sang-Hyun Oh1 1University of Minnesota, Minneapolis, USA, 2Centro Universitario de la Defensa de Zaragoza, SPAIN, 3Universidad de Zaragoza, SPAIN, and 4University of Maryland, Baltimore County, USA

d - Integrated Microfluidic Platforms Electrophoretic & Chromatographic Separation M1-134.d MIXED-SCALE FLUIDIC SYSTEM FOR POINT-OF-CARE TESTING Steven A. Soper1, Michael C. Murphy2, and Sunggook Park2 1University of Kansas, USA and 2Louisiana State University, USA

M2-232.d 3D PRINTING FOR ENHANCED FABRICATION OF MICROFLUIDIC FREE-FLOW ELECTROPHORESIS John-Alexander Preuss and Janina Bahnemann Leibniz Universität, Hannover, GERMANY

M2-233.d OVERCOMING MASS TRANSFER LIMITATIONS BY INTRODUCING VORTEX CHROMATOGAPHY Eiko Y. Westerbeek1,2, Guillermo Gonzalez Amaya1, Wouter Olthuis2, Jan C.T. Eijkel2, and Wim de Malsche1 1Vrije Universiteit Brussel, BELGIUM and 2University of Twente, THE NETHERLANDS

T3-333.d A MEDIUM THROUGHPUT SYSTEM FOR MEASUREMENT OF ISLET SECRETIONS Yao Wang, Weijia Leng, and Michael G. Roper Florida State University, USA

T3-334.d SUMMIT: A SEMI-AUTOMATED PROTEIN PEAK QUANTIFICATION ALGORITHM FOR HIGH- THROUGHPUT SINGLE-CELL ELECTROPHORESIS Julea Vlassakis1, Kevin A. Yamauchi1,2, and Amy E. Herr1 1University of California, Berkeley, USA and 2Friedrich Miescher Institute for Biomedical Research, SWITZERLAND

T4-433.d A MICROFLUIDIC IN-SITU SAMPLING PROBE INTEGRATED WITH LIQUID CHROMATOGRAPHIC SEPARATION CAPACITY FOR MASS SPECTROMETRY ANALYSIS Di-Qiong Jin, Shao-Wen Shi, Yan Ma, and Qun Fang Zhejiang University, CHINA

W5-532.d A MONOLITHIC 3D PRINTED µFFE DEVICE WITH INTEGRATED SWAB RECEPTACLE FOR ENRICHMENT OF MULTIDRUG-RESISTANT PATHOGENS Christian Neubert1, Ole Behrmann1, Denny Maaz2, Frank T. Hufert1, and Gregory Dame1 1Brandenburg Medical School Theodor Fontane, GERMANY and 2German Federal Institute for Risk Assessment, GERMANY

W6-632.d DETECTING CELL DEATH BY ELECTROPHORETIC CYTOMETRY Ana E. Gomez Martinez and Amy E. Herr University of California, Berkeley, USA

Th7-732.d DEVELOPMENT OF A NOVEL MICROFLUIDIC APPROACH FOR RAPID AND CONTINUOUS DETECTION OF PATHOGENS IN FOOD AND WATER SAMPLES Gurpreet Klar, Crystal M. Han, and Liat Rosenfeld San Jose State University, USA

Th8-832.d INTEGRATED SAMPLE PREPARATION FOR HIV MOLECULAR TESTING IN A PAPER-BASED DEVICE Andrew T. Bender1, Benjamin P. Sullivan1, Jane Y. Zhang1, Lorraine Lillis2, David S. Boyle2, and Jonathan D. Posner1 1University of Washington, USA and 2PATH, USA

d - Integrated Microfluidic Platforms Particle Separation M1-135.d HIGH THROUGHPUT EXTRACELLULAR VESICLE SORTING USING ELECTROKINETIC DETERMINISTIC LATERAL DISPLACEMENT Bao D. Ho, Jason P. Beech, and Jonas O. Tegenfeldt Lund University, SWEDEN

M1-136.d PARTICLE MANIPULATION USING PROGRAMMABLE HYDRODYNAMIC FORCES Ankur Kislaya, Daniel S.W. Tam, and Jerry Westerweel Delft University of Technology, THE NETHERLANDS

M2-234.d HIGH THROUGHPUT ISOLATION OF SMALL EXTRACELLULAR VESICLES FROM WHOLE BLOOD USING MULTIPLEXED SPIRAL MICROFLUIDICS (ExoDFFHT) Sheng Yuan Leong1, Hui Min Tay1, Megha Upadya1, Fang Kong1, Rinkoo Dalan2, Dao Ming1,3, and Han Wei Hou1 1Nanyang Technological University, SINGAPORE, 2Tan Tock Seng Hospital, SINGAPORE, and 3Massachusetts Institute of Technology, USA

M2-235.d POROUS PDMS SUBSTRATE-ASSISTED PARTICLE SORTING BASED ON HYDRODYNAMIC CROSS-FLOW MICROFLUIDIC FILTRATION Yurika Sakurai, Takeru Sato, Masumi Yamada, and Minoru Seki Chiba University, JAPAN

T3-335.d HIGH-THROUGHPUT CONTINUOUS INERTIAL FOCUSING OF MICROALGAE IN ASYMMETRIC SERPENTINE CHANNELS Mohammad Al-Hurani, Rodney Forster, Nicole Pamme, and Alex Iles University of Hull, UK

T3-336.d SCALING OF DLD DEVICES FOR CELL FRACTIONATION DOWN TO A SINGLE COLUMN FOR ULTRAHIGH THROUGHPUT PER AREA Weibin Liang, Robert H. Austin, and James C. Sturm Princeton University, USA

T4-434.d DETERMINISTIC LATERAL DISPLACEMENT OCCURS WITHOUT CONTACT AT INERTIAL FLOW RATES William J. Monck1, Calum P. Mallorie2, Rohan R. Vernekar2, Timm Krüger2, and David W. Inglis1 1Macquarie University, AUSTRALIA and 2University of Edinburgh, UK

T4-435.d MANIPULATION OF BIOMOLECULES USING A 3D-PRINTED INSULATOR-BASED DIELECTROPHORESIS DEVICE Mohammad Towshif Rabbani, Mukul Sonker, Jorvani Cruz Villarreal, and Alexandra Ros Arizona State University, USA

T4-436.d SHAPE BASED CHROMOSOME SEPARATION IN THE INERTIAL FOCUSING DEVICE Haidong Feng, Bruce Gale, Himanshu Sant University of Utah, USA

W5-533.d DETERMINISTIC LATERAL DISPLACEMENT SYSTEMS WITH ARRAYED THREE- DIMENSIONAL ELECTRODES FOR TUNABLE PARTICLE SORTING Gloria Porro1, Kevin Keim1, Giovanni Cappai1, Jason P. Beech2, Jonas O. Tegenfeldt2, and Carlotta Guiducci1 1École Polytechnique Fédérale de Lausanne (EPFL), SWITZERLAND and 2Lund University, SWEDEN

W5-534.d OPERATING SPIRAL INERTIAL MICROFLUIDICS AT CONCENTRATIONS UP TO 3.4X109 CELLS/ML FOR HIGH-CONCENTRATION DEWATERING OF CHLORELLA VULGARIS Catherine Hill, Nik Willoughby, and Helen Bridle Heriot-Watt University, UK

W5-535.d STREAM BIFURCATION INDUCED BLOOD CELL SEPARATION IN SEMI-DILUTED VISCOELASTIC FLOW Haidong Feng, Jules Magda, and Bruce K. Gale University of Utah, USA

W6-633.d DEVELOPING MICROFLUIDIC DEVICES AND TECHNIQUES FOR ISOLATION AND DETECTION OF EXTRACELLULAR VESICLES (EVS) Himayasri Rao Lekkala1, Ian Johnston1, Nikolay Dimov1, and Jameel Inal2,3 1University of Hertfordshire, UK, 2School of Life and Medical Sciences, UK, and 3London Metropolitan University, UK

W6-634.d PAPER-BASED PUMP-FREE MAGNETOPHORESIS Zachary D. Call, Cody S. Carrell, Ilhoon Jang, Brian J. Geiss, David S. Dandy, and Charles S. Henry Colorado State University, USA

W6-635.d UPSCALING OF DIELECTROPHORETIC CONTINUOUS-FLOW DNA SEPARATION IN A MICROFLUIDIC SYSTEM Jakob Derksen, Dario Anselmetti, and Martina Viefhues Bielefeld University, GERMANY

Th7-733.d FLOW FIELD-ASSISTED MICROFLUIDIC CHIP FOR THE SHEATHLESS SEPARATION OF MICROPARTICLES AND CELLS Shitao Shen1, Mingliang Jin1, Zichuan Yi2, Xing Li1, Zhibin Yan1, Guofu Zhou1, and Lingling Shui1,2 1South China Normal University, CHINA and 2University of Electronic Science and Technology of China, CHINA

Th7-734.d PARTICLE AND PATHOGEN FOCUSING AND PRE-ENRICHMENT IN ASYMMETRICALLY CURVED WINDING CHANNELS VIA INERTIAL MICROFLUIDICS Pablo Rodriguez-Mateos, Charlotte E. Dyer, Alexander Iles, and Nicole Pamme University of Hull, UK

Th8-833.d HIGH THROUGHPUT CLOGGING-FREE MICROFLUIDIC PARTICLE FILTER BY FEMTOSECOND LASER MICROMACHINING Filippo Storti1,2, Silvio Bonfadini1, and Luigino Criante1 1Istituto Italiano di Tecnologia, ITALY and 2Politecnico di Milano, ITALY

Th8-834.d PARTICLE MIGRATION IN SHEAR THINNING VISCOELASTIC FLUID Shamik Hazra1, Sushanta K. Mitra2, and Ashis Kumar Sen1 1Indian Institute of Technology, Madras, INDIA and 2University of Waterloo, CANADA

d - Integrated Microfluidic Platforms Micromixers & Microreactors M1-137.d HIGH-THROUGHPUT 3D GLASS MICROMIXER WITH AN IMPELLER MONOLITHICALLY FABRICATED USING SELECTIVE LASER-INDUCED ETCHING (SLE) Sungil Kim1,2, Jeongtae Kim1, Yeun-Ho Joung1, Sanghoon Ahn2, Jiyeon Choi2, and Chiwan Koo1 1Hanbat National University, KOREA and 2Korea Institute of Machinery and Materials (KIMM), KOREA

M2-236.d STUDY OF LIQUID PHASE OXIDATIVE DEGRADATION OF LIGNIN IN MICROFLUIDIC AND BATCH REACTOR Niloofar Manafi and Neda Nazemifard University of Alberta, CANADA

T3-337.d THE INFLUENCE OF SHEAR ON THE POLYMORPHISM OF ROY UNDER CONSTANT SHEAR CONDITIONS Sander Stroobants, Marzena Krezk, Pierre Gelin, Iwona Ziemecka, Yousef Pourvais, Heidi Ottevaere, Wim De Malsche, and Dominique Maes Vrije Universiteit Brussel, BELGIUM

T4-437.d THERMAL MANIPULATION FOR A SINGLE CELL UTILIZING AREA COOLING Yigang Shen1,2, Yaxiaer Yalikun1,3, Yusufu Aishan1,2, and Yo Tanaka1,2 1RIKEN, JAPAN, 2Osaka University, JAPAN, and 3Nava Institute of Science and Technology, JAPAN

Th7-735.d DEVELOPMENT OF A PILLAR ARRAY MIXER FOR POST-COLUMN DERIVATIZATION ON A CHIP Makoto Tsunoda, Muneki Isokawa, and Takashi Funatsu University of Tokyo, JAPAN Th8-835.d ENHANCEMENT OF PHOTOCATALYTIC REACTION ASSISTED BY NANOELECTROKINETICS Cong Wang and Jungyul Park Sogang University, KOREA

d - Integrated Microfluidic Platforms Chemical & Particle Synthesis M1-138.d PHOTOCHEMISTRY IN AN ASSEMBLY OF 108 MICROMETRIC CAPILARIES (id 3.65µm) GRAFTED WITH A PHOTOSENSITIZER Christian Rolando, Fabien Gelat, Christophe Penverne, Maël Penhoat, Géraud Bouwmans, and Laëtitia Chausset-Boissarie Université de Lille, FRANCE

W5-536.d A BOLT-NUT MICROREACTOR FOR THE SYNTHESIS OF CuInS2/ZnS QUANTUM DOTS Hyunbin Kim and Do Hyun Kim Korea Advanced Institute of Science and Technology (KAIST), KOREA

W6-636.d A CONTINUOUS PLATFORM FOR EMBEDDED DROPLET PRINTING OF PHARMACEUTICAL PARTICLES Arif Z. Nelson1, Jiaxun Xie2, Saif A. Khan2, and Patrick S. Doyle3 1Singapore-MIT Alliance for Research and Technology (SMART) Centre, SINGAPORE, 2National University of Singapore, SINGAPORE, and 3Massachusetts Institute of Technology, USA

Th7-736.d CHEMOENZYMATIC MICROFLUIDIC CASCADE REACTION: COUPLING OF A DIELS-ALDER REACTION WITH A TRANSKETOLASE-CATALYZED REACTION Mariana Santos1, Brian O'Sullivan1, Sarah Müller2, Alina Bunescu2, Frank Baganz1, Marco P.C. Marques1, Helen Hailes1, Nicolas Szita1, and Roland Wohlgemuth3 1University College London, UK, 2Sigma-Aldrich, GERMANY, and 3Technical University, Lodz, GERMANY

Th8-836.d DEVELOPMENT OF SYNTHESIS ROUTES TO HUMAN DRUG METABOLITES USING IMMOBILISED ENZYMATIC REACTIONS WITHIN MICROFLUIDIC REACTORS Bradley Doyle1, Leigh A. Madden1, Nicole Pamme1, and Huw S. Jones2 1University of Hull, UK and 2University of Bradford, UK

d - Integrated Microfluidic Platforms Other Applications in Chemistry M1-139.d DEVELOPMENT OF AN OPTIC MICRO-RHEOMETER USING MULTILAYER PMMA CARTRIDGES AND MODULAR POLYMERIC MICROPUMPS Yara Alvarez-Braña1, Josep Ferre-Torres2, Andreu Benavent-Claro2, Francisco Palacio-Bonet2, Fernando Benito-Lopez1, Mauricio Moreno-Sereno2, Aurora Hernandez-Machado2, and Lourdes Basabe-Desmonts1,3 1University of the Basque Country, SPAIN, 2University of Barcelona, SPAIN, and 3Basque Foundation of Science, IKERBASQUE, SPAIN

M2-237.d A DEVICE FOR URINE CELL CONCENTRATION, LYSIS AND NUCLEIC ACID AMPLIFICATION FOR CHLAMYDIA DETECTION AT THE POINT OF CARE Steven Bennett, Sujatha Kumar, Erin Heiniger, and Paul Yager University of Washington, USA

M2-238.d HYBRID MONOLITHS SUPPORTED ON FDM-BASED 3D-PRINTED SCAFFOLDS Marcella E.P. Schmidt, Lucas P. Bressan, José A.F. da Silva, and Carla B.G. Bottoli State University of Campinas, BRAZIL

T3-338.d A DISPOSABLE INTEGRATED DIAGNOSTIC DEVICE FOR BLOOD ACQUISITION, SAMPLE PROCESSING, LYSIS, AND DETECTION OF EBOLA VIRUS MARKERS Sujatha Kumar, Steven Bennett, Shichu Huang, Joshua Buser, and Paul Yager University of Washington, USA

T3-339.d PRE-CONCENTRATION WITH ELECTROSPUN MEMBRANES COUPLED WITH PAPER-BASED ASSAYS TOWARDS ONSITE MONITORING OF HEAVY METALS IN WATER Bongkot Ngamsom, Samantha Richardson, Mila Sari, Alexander Iles, Mark Lorch, Will M. Mayes, and Nicole Pamme University of Hull, UK

T4-438.d A MONOLITHIC WEARABLE SYSTEM DESIGN METHODOLOGY FOR PHYSIOLOGICAL ACTUATION AND ELECTROCHEMICAL SENSING Hannaneh Hojaiji, Yichao Zhao, Max C. Gong, Mudith Mallajosyula, Amir M. Hojaiji, Asad M. Madni, and Sam Emaminejad University of California, Los Angeles, USA

W5-537.d ACCELERATED MICROFLUIDIC STUDIES OF SWITCHABLE HYDROPHILICITY SOLVENTS Suyong Han, Mahdi Ramezani, and Milad Abolhasani North Carolina State University, USA

W6-637.d AMYLOID ß ANALYSIS FROM MICRODISSECTED BRAIN CELLS USING MICROFLUIDICS AND MALDI MASS SPECTROMETRY Jorvani Cruz Villarreal, Ana Egatz-Gomez, Jiawei Liu, Robert Ros, Paul D. Coleman, and Alexandra Ros Arizona State University, USA

Th7-737.d AN INTEGRATED CENTRIFUGAL DEGASSED PDMS-BASED MICROFLUIDIC DEVICE FOR SERIAL DILUTION Anyang Wang, Samaneh Moghadasi Boroujeni, Stelios T. Andreadis, and Kwang W. Oh University at Buffalo, USA

Th8-837.d DEVELOPING THE FUTURE OF CLINICAL RADIOPHARMACY: OPTIMISING ON-CHIP GALLIUM-68 RADIOLABELLING FOR PET IMAGING Vincent Nail, Mark D. Tarn, Ping He, Nicole Pamme, and Stephen J. Archibald University of Hull, UK

d - Integrated Microfluidic Platforms Industrial Benefactor W5-538.d HOLIFAB: MICROFLUIDIC INTEGRATION PILOT LINE AND CAD SOFTWARE FOR COMMERCIALIZATION OF YOUR MICROFLUIDIC SET-UP Nicolas Lafitte, Mikael Trellet, Ygor Oliveira, Benjamin Rouffet, Serge Renouard, and Jean-Louis Viovy Holifab/Fluigent, FRANCE

d - Integrated Microfluidic Platforms Late News M1-178.d MULTI-LAYERED CLASSIFICATION BY DNA BASED COMPUTING WITH DROPLET PLATFORM Shu Okumura1, Guillaume Gines2, Nicolas Lobato-Dauzier1, Robin Deteix1, Alexandre Baccouche1, Teruo Fujii1, Yannick Rondelez2, and Anthony J. Genot1 1University of Tokyo, JAPAN and 2ESPCI Paris, FRANCE

W6-678.d HIGHLY EFFICIENT EXOSOME PURIFICATION FROM HUMAN PLASMA BY TANGENTIAL FLOW FILTRATION BASED MICROFLUIDIC CHIP Zhenzhen Han1, Cheng Peng2, Jia Yi1, Dongxue Zhang1, Bin Su3, Baohong Liu1, Yuhui Shen2, and Liang Qiao1 1Fudan University, CHINA, 2Shanghai Jiao Tong University School of Medicine, CHINA, and 3Zhejiang University, CHINA

Th7-777.d DROPLET MICROFLUIDICS TO ENGINEER SMART BUILDING BLOCKS FOR MODULAR TISSUE ENGINEERING Niels Willemen, Tom Kamperman, Cindy Kelder, Michelle Koerselman, João Crispim, Jan Hendriks, Sieger Henke, Xandra De Peuter, Piet Dijkstra, Marcel Karperien, and Jeroen Leijten University of Twente, NETHERLANDS

Th8-875.d INTEGRATED IMPEDANCE SENSORS IN A MICROFLUIDIC SYSTEM: TOWARD A FULLY AUTOMATED HIGH THROUGHPUT NMR SPECTROSCOPY Omar Nassar, Mazin Jouda, Jan Korvink, Dario Mager, and Neil Mackinnon Karlsruhe Institute of Technology, GERMANY

e - Cells, Organisms and Organs on a Chip Cell Capture, Counting, & Sorting M1-140.e FULLY-AUTOMATED AND FIELD-DEPLOYABLE BLOOD SEPARATION PLATFORM USING MULTI-DIMENSIONAL DOUBLE SPIRAL (MDDS) INERTIAL MICROFLUIDICS Hyungkook Jeon1,2 and Jongyoon Han1 1Massachusetts Institute of Technology, USA and 2Pohang University of Science and Technology, KOREA

M1-141.e PORTABLE PLATELET APHERESIS SYSTEM Lap Man Lee, Ketan H. Bhatt, Dustin W. Haithcock, Balabhaskar Prabhakarpandian, and Kapil Pant CFD Research Corporation, USA

M1-142.e ULTRASENSITIVE DETECTION AND DEPLETION OF RARE LEUKEMIC B CELLS IN T CELL POPULATIONS VIA MICROFLUIDICS-MEDIATED IMMUNOMAGNETIC CELL RANKING Zongjie Wang and Shana O. Kelley University of Toronto, CANADA

M2-239.e GENTLE TRAP-AND-RELEASE MECHANISM FOR MULTISTEP CELL PROCESSING USING PDMS SPONGE-INTEGRATING MICROFLUIDIC DEVICES Natsumi Miura, Masumi Yamada, and Minoru Seki Chiba University, JAPAN

M2-240.e RARE CELLS ISOLATION ON SACA CHIP FOR AUTOMATIC CELLS ANALYSIS Yi-Wen Hu1, Ping-Hao Yeh1, Hsin-Yao Wu1, and Fan-Gang Tseng1,2 1National Tsing Hua University, TAIWAN and 2Academia Sinica, TAIWAN

T3-340.e HIGH-THROUGHPUT LIVE CELL PRINTING SYSTEM USING NEAR INFRA-RED PULSE LASER Amos Chungwon Lee, Wooseok Lee, Yongju Lee, Ahyoun Choi, Sudeok Kim, Kyoung Seob Shin, and Sunghoon Kwon Seoul National University, KOREA

T3-341.e SAFELY SORTING AND ISOLATING RARE SPERM USING DIELECTROPHORESIS BY TRAPPING THE TAIL AND SIMULTANEOUSLY DISTANCING THE HEAD FROM STRONG ELECTRIC FIELDS Sholom Shuchat1, Ofer Fainaru2, Shahar Kol3, and Gilad Yossifon1 1Technion – Israel Institute of Technology, ISRAEL, 2Rappaport Faculty of Medicine, ISRAEL, and 3Elisha Hospital, Haifa Israel, ISRAEL

T4-439.e A DROPLET-BASED DETECTION AND SORTING OF CELLS UTILIZING OPTOFLUIDICS AND ELECTRO- COALESCENCE TECHNIQUE Ravindra Gaikwad and Ashis K. Sen Indian Institute of Technology, Madras, INDIA

T4-440.e HIGH-THROUGHPUT SINGLE-CELL QUANTIFICATION OF ELASTIC MODULUS Ryan Dubay1,2, Jason Fiering2, and Eric M. Darling1 1Brown University, USA and 2Draper, USA

T4-441.e SELECTIVE RETRIEVAL OF INDIVIDUAL CELLS FROM MICROFLUIDIC ARRAYS COMBINING DIELECTROPHORETIC FORCE AND DIRECTED HYDRODYNAMIC FLOW Pierre-Emmanuel Thiriet, Joern Pezoldt, Gabriele Gambardella, Kevin Keim, Bart Deplancke, and Carlotta Guiducci École Polytechnique Fédérale de Lausanne (EPFL), SWITZERLAND

W5-539.e CELL SORTING ACROSS LAMINAR INTERFACE USING STIFFNESS CONTRAST Shamik Hazra1, Sushanta K. Mitra2, and Ashis Kumar Sen1 1Indian Institute of Technology, Madras, INDIA and 2University of Waterloo, CANADA

W5-540.e LABEL-FREE SINGLE-CELL CAPTURE AND RELEASE VIA A FIRST-IN FIRST-OUT MICROFLUIDIC CELL ROUTER Nathaniel Liu, Kristina Chan, and Lydia L. Sohn University of California, Berkeley, USA

W5-541.e SINGLE CELL PER WELL TRAPPING AND ANALYSIS OF CHLAMYDOMONAS REINHARDTII USING SURFACE ACOUSTIC WAVES Mingyang Cui, Philip V. Bayly, Susan K. Dutcher, and J. Mark Meacham Washington University, St. Louis, USA

W6-638.e DEFORMABILITY BASED CELL SORTING AS A BIOMARKER FOR THE QUALITY OF STORED RED BLOOD CELLS Emel Islamzada1, Kerryn Matthews1, Erik Lamoureux1, Quan Guo1, Aline T. Santoso1, Mark D. Scott1,2, and Hongshen Ma1,3 1University of British Columbia, CANADA, 2Canadian Blood Services, CANADA, and 3Vancouver General Hospital, CANADA

W6-639.e MICROFLUIDIC MEDIUM EXCHANGER WITH MICROPORED FLUID DRAINAGE FOR CELL CULTURE APPLICATIONS Takeru Sato, Yurika Sakurai, Masumi Yamada, and Minoru Seki Chiba University, JAPAN

W6-640.e SPIRAL MICROFLUIDICS ENHANCED ISOLATION OF EPITHELIAL CELLS FROM INFECTED MICE URINE Suhanya Duraiswamy1, Lin Yue Lanry Yung2, and Swaine L. Chen2 1Indian Institute of Technology, Hyderabad, INDIA, 2National University of Singapore, SINGAPORE, and 3Genome Institute of Singapore, SINGAPORE

Th7-738.e FABRICATION OF CMOS-COMPATIBLE GRAPHENE MICROHALL SENSORS FOR MAGNETIC CYTOMETRY Nishal Shah, Vasant Iyer, and David Issadore University of Pennsylvania, USA

Th7-739.e MICROFLUIDIC TRAP ARRAYS FOR PROBING STOCHASTIC IMMUNE-TUMOR DYNAMICS Michael C. Yeh1,2, Emanuel Salazar Cavazos2, Supriya Padmanabhan1, Grégoire Altan-Bonnet2, and Don L. DeVoe1 1University of Maryland, College Park, USA and 2National Cancer Institute, USA

Th7-740.e TECHNIQUE FOR PASSIVE DROPLET SORTING AFTER PHOTO-TAGGING Chandler Dobson, Claudia Zielke, Ching Pan, Cameron Feit, and Paul Abbyad Santa Clara University, USA *poster will be presented during the M2 poster session on Monday

Th8-838.e FERTDISH: MICROFLUIDIC SPERM SELECTION-IN-A-DISH FOR ICSI Sa Xiao1, Jason Riordon1, Alexander Lagunov2, Tom Hannam2, Reza Nosrati3, and David Sinton1 1University of Toronto, CANADA, 2Hannam Fertility Centre, CANADA, and 3Monash University, AUSTRALIA

Th8-839.e PAIRING CELLS WITH DIFFERENT DIMENSIONS IN A MICROFLUIDIC DEVICE USING A UNIDIRECTIONAL FLOW Faruk A. Shaik1, Clara Lewuillon1,2, Yasmine Touil1,2, Aurélie Guillemette1,2, Bruno Quesnel1,2, Carine Brinster1,2, Loic Lemonnier2, Dominique Collard3, and Mehmet C. Tarhan1,4 1University of Lille, FRANCE, 2INSERM, FRANCE, 3University of Tokyo, FRANCE, and 4University Valenciennes, FRANCE

Th8-840.e THE EFFECT OF ELEVATED HEMATOCRIT ON HUMAN BLOOD FLOW IN A MICROCHANNEL Md Ehtashamul Haque1,2, Krystian Wlodarczyk1, Duncan P. Hand1, Miguel O. Bernabeu2, and Maïwenn Kersaudy-Kerhoas1,2 1Heriot Watt University, UK and 2Edinburgh University, UK

e - Cells, Organisms and Organs on a Chip Single-Cell Analysis M1-143.e LABEL-FREE ASSESSMENT OF CELL CYCLE SYNCHRONIZATION IN NEURAL PROGENITOR CELLS BY IMPEDANCE CYTOMETRY Carlos Honrado, Nadine Michel, John H. Moore, Armita Salahi, Veronica Porterfield, Michael J. McConnell, and Nathan S. Swami University of Virginia, USA

M1-144.e ELECTROROTATION FOR SINGLE CELL ANALYSIS OF MEMBRANE DAMAGE INDUCED BY TOXINS MIMICKING THE NEURODEGENERATIVE EFFECT OF AMYLOID BETA IN THE ALZHEIMER'S DISEASE Till Ryser, Kevin Keim, Anne-Laure Mahul-Mellier, Hilal Lashuel, and Carlotta Guiducci École Polytechnique Fédérale de Lausanne (EPFL), SWITZERLAND

M1-145.e MICROFLUIDIC HANGING PILLARS ARRAYS FOR SINGLE-CELL ANALYSIS OF OSMOTIC SWELLING DYNAMICS AS PHYSICAL BIOMARKERS Apresio K. Fajrial, Kun Liu, Yu Gao, and Xiaoyun Ding University of Colorado, Boulder, USA

M1-146.e SPATIALLY RESOLVED GENOMICS FROM SINGLE CELLS WITH DISTINCT FLUORESCENT SIGNALS USING TRANSPOSASE-BASED DIRECT LIBRARY PREPARATION Ahyoun Choi1, Amos Chungwon Lee1, Yongju Lee1, Jinhyun Kim1, Kyoung Seob Shin1, Dajeong Jeong2, Myoung Hee Ham2, Sung-Min Kim3, Okju Kim4, Yushin Jung4, Changhoe Kim4, Taehoon Ryu4, Dongsoon Lee2,3, and Sunghoon Kwon1 1Seoul National University, KOREA, 2Seoul National University Hospital, KOREA, 3Seoul National University College of Medicine, KOREA, and 4Celemics, Inc., KOREA

M2-241.e 3D PROJECTION ELECTROPHORESIS FOR HIGH-DENSITY SINGLE-CELL IMMUNOBLOTTING Samantha M. Grist, Andoni P. Mourdoukoutas, and Amy E. Herr University of California, Berkeley, USA

M2-242.e BIOMECHANICAL MARKERS FOR MONITORING HETEROGENEITY IN ISLET REORGANIZATION DYNAMICS WITH ADIPOSE STEM CELLS Karina Torres-Castro, Mohammad S. Azimi, Walter B. Varhue, Carlos Honrado, Shayn M. Pierce-Cottler, and Nathan S. Swami University of Virginia, USA

M2-243.e HIGH-THROUGHPUT QUANTIFICATION OF SINGLE-CELL CORTICAL TENSION USING MUTIPLE CONSTRCTION CHANNELS Ke Wang1, Yan Liu2,3, Xiaohao Sun4, Deyong Chen2,3, Junbo Wang2,3, and Jian Chen2,3 1Beijing University of Posts and Telecommunications, CHINA, 2Chinese Academy of Sciences, CHINA, 3University of Chinese Academy of Sciences, CHINA, and 4University of Colorado Boulder, USA

M2-244.e MONITORING THE GROWTH PHASES OF MICROALGAE USING STRAIGHTFORWARD DIELECTROPHORESIS MEASUREMENTS Yu-Sheng Lin1,2, Bruno Le Pioufle2, and Hsiang-Yu Wang1 1National Tsing Hua University, TAIWAN and 2Université Paris Saclay, FRANCE

M2-245.e SPATIALLY TARGETED WHOLE TRANSCRIPTOME ACCESSIBLE IN SITU SEQUENCING Kyoungseob Shin2, Hower Lee1, Yongju Lee1, Ahyoun Choi2, Amos Chungwon Lee2, Narayanan Madaboosi1, Mats Nilsson1, and Sunghoon Kwon2 1Stockholm University, SWEDEN and 2Seoul National University, KOREA

T3-342.e A DUAL IMAGING SYSTEM FOR UNDERSTANDING MICROSWIMMER LOCOMOTION Farzan Akbaridoust1,2, Ivan Marusic2, and Reza Nosrati1 1Monash University, AUSTRALIA and 2University of Melbroune, AUSTRALIA

T3-343.e CONSTRICTION CHANNEL BASED MICROFLUIDIC SYSTEM OF QUANTIFYING SINGLE- CELL CYTOPLASMIC VISCOSITY, CYTOPLASMIC CONDUCTIVITY AND SPECIFIC MEMBRANE CAPACITANCE Yan Liu1, Ke Wang2, Xiaohao Sun3, Deyong Chen1, Junbo Wang1, and Jian Chen1 1Chinese Academy of Sciences, CHINA, 2Beijing University of Posts and Telecommunications, CHINA, and 3University of Colorado Boulder, USA

T3-344.e IMPEDANCE CYTOMETRY OF APOPTOTIC BODIES TO QUANTIFY DRUG SENSITIVITY OF PANCREATIC TUMOR XENOGRAFTS Carlos Honrado, John H. Moore, Sara J. Adair, Armita Salahi, Todd W. Bauer, and Nathan S. Swami University of Virginia, USA

T3-345.e MULTIPLEXED RESISTIVE–PULSE SENSING THROUGH CODED NODE–PORE CHANNEL GEOMETRY Kristen L. Cotner1 and Lydia L. Sohn1,2 1UC Berkeley – UCSF Graduate Program in Bioengineering, USA and 2University of California, Berkeley, USA

T3-346.e VIBRATIONAL FLOW CYTOMETRY ON A CHIP: A LABEL-FREE TOOL FOR METABOLIC PHENOTYPING Julia Gala de Pablo1, Matthew Lindley1, Kotaro Hiramatsu1,2, Akihiro Isozaki1,2, and Keisuke Goda1,3,4 1University of Tokyo, JAPAN, 2Kanagawa Institute of Industrial Science and Technology, JAPAN, 3University of California, Los Angeles, USA, and 4Wuhan University, JAPAN

T4-442.e A GENETIC NETWORK FOR THE COMMUNICATION AND SYNCHRONIZATION OF NEUROSPORA CRASSA Xiao Qiu, Jia Hwei Cheong, Heinz-Bernd Schüttler, Jonathan Arnold, and Leidong Mao University of Georgia, USA

T4-443.e DETECTING MULTIPLEX MUTATION IN SINGLE MELANOMA CELLS USING MOLECULAR BEACONS IN LOOP-MEDIATED ISOTHERMAL AMPLIFICATION (MB-LAMP) Darshna Pagariya, Marcelino Varona, Jared L. Anderson, and Robbyn K. Anand Iowa State University, USA

T4-444.e MACHINE LEARNING-ENABLED HIGH-SPEED IMPEDANCE CYTOMETRY Federica Caselli1, Adele De Ninno1,2, Riccardo Reale1, Luca Businaro2, and Paolo Bisegna1 1University of Rome Tor Vergata, ITALY and 2Italian National Research Council, ITALY

T4-445.e OCEAN CARBON CYCLE STUDIED BY SINGLE-CELL IMPEDANCE CYTOMETRY ON CALCIFYING ALGAE Douwe S. de Bruijn1, Paul M. ter Braak1, Dedmer B. Van de Waal2, Wouter Olthuis1, and Albert van den Berg1 1University of Twente, THE NETHERLANDS and 2Netherlands Institute of Ecology (NIOO-KNAW), THE NETHERLANDS

W5-542.e A HIGH-THROUGHPUT MEMS DEVICE FOR MECHANICAL DETECTION OF CANCER CELLS Quentin Rezard1,2, Grégoire Perret1,3, Jean Claude Gerbedoen1,3, Deniz Pekin3,4, Dominique Collard1,3, Chann Lagadec1,4, and Mehmet C. Tarhan1,2 1University of Lille, FRANCE, 2University of Valenciennes, FRANCE, 3University of Tokyo, JAPAN, and 4INSERM, FRANCE

W5-543.e DETERMINISTIC CELL-BEAD AND CELL-CELL PAIRING AND ENCAPSULATION Rafal Krzysztoń, Martin Sauzade, and Eric Brouzes Stony Brook University, USA

W5-544.e LIGHT-SHEET IN A µTAS FOR SINGLE CELL IMAGING Erick Vargas-Ordaz1, Sergey Gorelick1, Adrian Neild1, Alex de Marco1,2, and Victor J. Cadarso1,3 Monash University, AUSTRALIA, 2University of Warwick, UK, and 3Melbourne Centre for Nanofabrication, AUSTRALIA

W5-545.e OPTIMIZATION OF MARINE BACTERIA MICROENCAPSULATION FOR THE DISCOVERY OF NOVEL MARINE NATURAL PRODUCTS Emily Pope, Tartela Alkayyali, Sydney Wheatley, Christopher Cartmell, Jultwahnique MacDonald, Bradley Haltli, Russell G. Kerr, and Ali Ahmadi University of Prince Edward Island, CANADA

W6-641.e A HYPERBOLIC MICROFLUIDIC IMPEDANCE CHIP FOR DEFORMABILITY CYTOMETRY Riccardo Reale1, Adele De Ninno1,2, Luca Businaro2, Paolo Bisegna1, and Federica Caselli1 1University of Rome Tor Vergata, ITALY and 2Italian National Research Council, ITALY

W6-642.e DIRECT QUANTIFICATION OF SINGLE CELL DRUG UPTAKE Erika J. Fong1, Nick. R. Hum1,2, Kelly A. Martin1, Melinda Simon3, Gaby G. Loots1,2, and Ted J. Ognibene1 1Lawrence Livermore National Laboratory, USA, 2University of California, Merced, USA and 3San Jose State University, USA

W6-643.e MACROMOLECULE DELIVERY INTO HARD-TO-TRANSFECT PRIMARY CELLS VIA HYDRODYNAMIC CELL DEFORMATION Jeongsoo Hur and Aram Chung Korea University, KOREA

W6-644.e PHENOTYPE BASED SELECTIVE SINGLE CELL ISOLATION USING NEAR-INFRARED PULSE LASER FOR SPATIALLY RESOLVED OMICS ANALYSIS Yongju Lee1, Amos Chungwon Lee1, Ahyoun Choi1, Kyoungseob Shin1, Okju Kim2, Yushin Jung2, Changhoe Kim2, Taehoon Ryu2, and Sunghoon Kwon1 1Seoul National University, KOREA and 2Celemics, Inc., KOREA

Th7-741.e A MICROFLUIDIC DEVICE TO MEASURE THE SHEAR ELASTIC MODULUS OF SINGLE RED BLOOD CELLS Ninad Mehendale1, Savita Kumari1, Priyanka Naik1, Dhrubaditya Mitra2,3, and Debjani Paul1 1Indian Institute of Technology, Bombay, INDIA, 2KTH Royal Institute of Technology, SWEDEN, and 3Stockholm University, SWEDEN

Th7-742.e DROPLET MICROFLUIDICS FOR STUDIES OF BACTERIAL GENETIC TRANSFORMATION IN STREPTOCOCCUS PNEUMONIAE Trinh Lam, Mark Maienschein-Cline, David T. Eddington, and Donald A. Morrison University of Illinois, Chicago, USA

Th7-743.e MARKERS FOR ASTROGENESIS IN HETEROGENEOUS NEURAL STEM CELL SAMPLES BY SINGLE-CELL IMPEDANCE CYTOMETRY John Moore1, Carlos Honrado1, Armita Salahi1, Alan Jiang2, Andrew Yale2, Lisa Flannagan2, and Nathan S. Swami1 1University of Virginia, USA and 2University of California, Irvine, USA

Th7-744.e RED BLOOD CELLS AS MODEL PARTICLES WITH MODULATED SUBCELLULAR ELECTROPHYSIOLOGY FOR IMPEDANCE CYTOMETRY Armita Salahi, Carlos Honrado, and Nathan S. Swami University of Virginia, USA

Th8-841.e ACTIVE PARTICLE BASED SELECTIVE TRANSPORT AND RELEASE OF CELL ORGANELLES AND MECHANICAL PROBING OF A SINGLE NUCLEUS Yue Wu, Afu Fu, and Gilad Yossifon Technion – Israel Institute of Technology, ISRAEL

Th8-842.e ELECTRICAL SENSING OF SICKLED RED BLOOD CELLS SUBPOPULATIONS IN MICROFLUIDIC DEVICE Tieying Xu1, Maria A. Lizarralde-Iragorri2, Jean Roman1, Emile Martincic3, Valentine Brousse2, Olivier Français4, Wassim El Nemer2, and Bruno Le Pioufle1 1Université Paris-Saclay, FRANCE, 2Université de Paris, FRANCE, 3Université Paris-Sud, FRANCE, and 4University Gustave Eiffel, FRANCE

Th8-843.e MATCHING AND COMPARING OBJECTS IN A SERIAL CYTOMETER Nikita Podobedov1,2, Matthew DiSalvo2,3, Jason Hsu2,4, Paul Patrone2, and Gregory A. Cooksey2 1Columbia University, USA, 2National Institute of Standards and Technology (NIST), USA, 3Johns Hopkins University, USA, and 4Montgomery Blair High School, USA

Th8-844.e SERIAL MICROFLUIDIC CYTOMETRY WITH INERTIAL AND HYDRODYNAMIC FLOW FOCUSING Matthew DiSalvo1,2, Paul N. Patrone2, and Gregory A. Cooksey2 1Johns Hopkins University, USA and 2National Institute of Standards and Technology (NIST), USA

e - Cells, Organisms and Organs on a Chip Cell-Culturing & Perfusion (2D & 3D) M1-147.e AN ENZYME-FREE AND ULTRAFAST CELL-DISSOCIATION TECHNIQUE FOR CELL CULTURE APPLICATIONS USING ACOUSTOFLUIDICS Alinaghi Salari1,2, Sila Appak-Baskoy1,2, Imogen R. Coe1, Scott S.H. Tsai1,2, and Michael C. Kolios1,2 1Institute for Biomedical Engineering, Science and Technology (iBEST), CANADA and 2Ryerson University, CANADA

M1-148.e MODULAR TISSUE ASSEMBLY FOR FABRICATION OF COMPLEX AND SCALED UP TISSUE Byeongwook Jo, Yuya Morimoto, and Shoji Takeuchi University of Tokyo, JAPAN

M1-149.e TUNABLE 3D IN VITRO ARTERY-MIMICKING MULTICHANNEL SYSTEM FOR DISEASE MODELING Minkyung Cho and Je-Kyun Park Korea Advanced Institute of Science and Technology (KAIST), KOREA

M2-246.e DIRECTING SELF-ORGANIZATION AND DIFFERENTIATION OF STEM CELLS USING A MICROMESH SUSPENSION CULTURE Kennedy O. Okeyo, Yuta Ando, and Taiji Adachi Kyoto University, JAPAN

M2-247.e NEW MICROFLUIDIC DESIGNS FOR HIGH-THROUGHPUT ANALYSIS OF ANGIOGENESIS, BLOOD VESSEL PERMEABILITY AND ENDOTHELIAL ACTIVATION Elise Delannoy1,2, Anthony Treizebre2, and Fabrice Soncin1 1Lille University, FRANCE and 2University Polytechnique Hauts-de-France, FRANCE

M2-248.e Z-WIRE – A MICRO-SCAFFOLD THAT SUPPORTS GUIDED TISSUE ASSEMBLY AND INTRAMYOCARDIUM DELIVERY FOR CARDIAC REPAIR Luis E. Portillo-Esquivel, Vibudha Nanduri, Feng Zhang, Wenbin Liang, and Boyang Zhang McMaster University, CANADA

T3-347.e FLOW-THROUGH CELL CULTURE SYSTEM USING MICROCAVITIES EMBEDDED IN SPONGELIKE PDMS MATRIX Mai Takagi, Masumi Yamada, and Minoru Seki Chiba University, JAPAN

T3-348.e RAPID PROTOTYPING OF CONCAVE MICROWELLS FOR SPHEROID CULTURE BY COMBINING MICROMILLING AND CARAMEL REPLICA MOULDING Zhiyuan Dong, Bangyong Sun, and Gang Li Chongqing University, CHINA

T4-446.e 3D CO-CULTURED MULTICELLULAR SPHEROIDS ON MICROFLUIDIC CHIP FOR STUDYING ECM-MEDIATED DRUG RESISTANCE Venkanagouda S. Goudar1, Long Sheng Lu2, Manohar Prasad Koduri1, and Fan-Gang Tseng1,3 1National Tsing Hua University, TAIWAN, 2Taipei Medical University Hospital, TAIWAN, and 3Academia Sinica, TAIWAN

T4-447.e FORMATION OF CONTRACTILE SKELETAL MUSCLE TISSUE WITH TENDON TISSUE AT BOTH ENDS Yuya Morimoto, Shigenori Miura, and Shoji Takeuchi University of Tokyo, JAPAN

T4-448.e REPLICA MOLDING OF THIOL-ENE MICROWELL ARRAYS FOR MICROFLUIDIC 3D CELL SPHEROID CULTURING Päivi Järvinen1, Sari Tähkä1, Ashkan Bonabi1, Ville Jokinen2, and Tiina Sikanen1 1University of Helsinki, FINLAND and 2Aalto University, FINLAND

W5-546.e 3D PRINTED DEVICE FOR 96-WELL HYDROSTATIC PRESSURE CONTROL Adam Szmelter and David Eddington University of Illinois, Chicago, USA

W5-547.e HIGHLY PARALLELIZED HUMAN EMBRYONIC STEM CELL DIFFERENTIATION IN NANOLITER CHAMBERS Anke R. Vollertsen, Simone A. ten Den, Verena Schwach, Albert van den Berg, Robert Passier, Andries D. van der Meer, and Mathieu Odijk University of Twente, THE NETHERLANDS

W5-548.e SEQUESTERING EXTRACELLULAR VESICLE PROFILES IN NEUROFLUIDICS Zeynep Malkoc, Stephanie E. McCalla, and Anja Kunze Montana State University, USA

W6-645.e A DROPLET MICROFLUIDIC PLATFORM FOR GENERATING STEM CELL-DERIVED AND LONG-LASTING HUMAN LIVER MICROTISSUES Regeant Panday1, David A. Kukla1, Alexandra L. Crampton2, David K. Wood2, and Salman R. Khetani1 1University of Illinois, Chicago, USA and 2University of Minnesota, USA

W6-646.e INTEGRATED HEPATOCYTE SPHEROID FORMATION AND ENCAPSULATION FOR SYSTEMATIC STUDY OF EXTRACELLULAR MATRIX EFFECT Shuai Deng, Yanlun Zhu, Xiaoyu Zhao, and Hon Fai Chan Chinese University of Hong Kong, CHINA

W6-647.e SIMPLE CHEMICAL GRADIENT GENERATION FOR A SPHEROID CULTURE ARRAY Panhui Yang, Lei Wu, and Hongju Mao Chinese Academy of Sciences, CHINA

Th7-745.e A MICROFLUIDIC ORGANOID TRAPPING DEVICE TO FORM TUBE-LIKE INTESTINAL ORGANOIDS Miki Matsumoto1, Yuya Morimoto1, Toshiro Sato2, and Shoji Takeuchi1 1University of Tokyo, JAPAN and 2Keio University School of Medicine, JAPAN

Th7-746.e INTERPENETRATING HYDROGEL NETWORK BASED ON 3D-PRINTABLE ENDOTHELIAL CELLS COCULTURED WITH FIBROBLASTS Soo Jee Kim, Gihyun Lee, and Je-Kyun Park Korea Advanced Institute of Science and Technology (KAIST), KOREA

Th7-747.e SKIN-EQUIVALENT CULTURE DEVICE FOR APPLYING VERTICAL COMPRESSION Satoshi Inagaki, Keigo Nishimura, Yuya Morimoto, and Shoji Takeuchi University of Tokyo, JAPAN

Th8-845.e A SIMPLE METHOD TO ANALYZE NATURAL HYPOXIA EXPRESSION IN JUMBO SPHEROIDS ON-CHIP Elena Refet-Mollof1,2, Ouafa Najyb2, Rodin Chermat1,2, Julie Lafontaine2, Philip Wong2, and Thomas Gervais1,2 1Polytechnique Montréal, CANADA and 2Centre Hospitalier de l’Université de Montréal, CANADA

Th8-846.e MODELING CTC CLUSTERS USING 3D-PRINTED AGAROSE MICROWELLS Qiyue Luan, Jian Zhou, Celine Macaraniag, and Ian Papautsky University of Illinois, Chicago, USA

Th8-847.e TIME-LAPSE IMAGING OF MOUSE EMBRYONIC STEM CELLS USING AN AUTOMATED MICROFLUIDIC DEVICE Adam F. Laing1, Venkat Tirumala1, Evan Hegarty1, Sudip Mondal1, Peisen Zhao1, William B. Hamilton2, Joshua M. Brickman2, and Adela Ben-Yakar1 1University of Texas, Austin, USA and 2University of Copenhagen, DENMARK

e - Cells, Organisms and Organs on a Chip Inter-& Intracellular Signaling, Cell Migration T3-349.e A CIRCULATING CO-CULTURE MICROFLUIDIC DEVICE FOR THE DYNAMIC SAMPLING OF PARACRINE FACTORS Emmaline F. Miller1, Jacy Busboom2, Joshua J. Clavin1, Elizabeth C. Martin1, and Adam T. Melvin1 1Louisiana State University, USA and 2University of Wyoming, Laramie, USA

T4-449.e A MODULAR GRANULOMA MODEL FOR MICROENVIRONMENT SIGNALING STUDIES IN VITRO Maia S. Gower, Samuel B. Berry, Xiaojing Su, Chetan Seshadri, and Ashleigh B. Theberge University of Washington, USA

W5-549.e DENDRITIC CELL MIGRATION IN 2D CONFINED ENVIRONMENT Yongjun Choi1,2 and Yoon-Kyoung Cho1,2 1Ulsan National Institute of Science & Technology (UNIST), KOREA and 2Institute for Basic Science (IBS), KOREA

W6-648.e HIGH THROUGHPUT INTRACELLULAR DELIVERY FACILITATED BY ACOUSTOFLUIDICS Alinaghi Salari1,2, Sila Appak-Baskoy1,2, Imogen R. Coe2, John Abousawan2, Costin N. Antonescu2, Scott S.H. Tsai1,2, and Michael C. Kolios1,2 1Institute for Biomedical Engineering, Science and Technology (iBEST), CANADA and 2Ryerson University, CANADA

Th7-748.e MICROFLUIDIC CHAMBER DEVICE TO TEST QUORUM SENSING THEORY Jia Hwei Cheong, Xiao Qiu, Yang Liu, James Griffith, Heinzr Bernd Schüttler, Jonathan Arnold, and Leidong Mao University of Georgia, USA

Th8-848.e MULTIPLEXED END-POINT MICROFLUIDIC CHEMOTAXIS ASSAY USING CENTRIFUGAL ALIGNMENT Pan Deng1, Sampath Satti1, Kerryn Matthews1, Simon P. Duffy1,2, and Hongshen Ma1,3 1University of British Columbia, CANADA, 2British Columbia Institute of Technology, CANADA, and 3Vancouver General Hospital, CANADA

e - Cells, Organisms and Organs on a Chip Organisms on Chip (C. elegans, Zebrafish, Arabidopsis, etc.) M1-150.e AN ULTRA-HIGH-DENSITY MICROFLUIDIC PLATFORM TO IMAGE C. ELEGANS FOR HIGH- CONTENT PHENOTYPIC SCREENS Sudip Mondal, Evan Hegarty, Chris Martin, Sertan K. Gökçe, and Adela Ben-Yakar University of Texas, Austin, USA

M1-151.e MICROFLUIDIC DEVICE TO SCREEN THE ELECTRIC INDUCED BEHAVIORAL RESPONSE OF MULTIPLE ZEBRAFISH LARVAE Arezoo Khalili, Ellen van Wijngaarden, Khaled Youssef, Georg Zoidl, and Pouya Rezai York University, CANADA

M2-249.e CONTROLLABLE MICROFLUIDIC ROTATION OF CAENORHABDITIS ELEGANS Peng Pan1,2, John D. Laver1, Zhen Qin1, Yuxiao Zhou1, Ran Peng1, Lijun Zhao3, Hui Xie3, John A. Calarco1, and Xinyu Liu1 1University of Toronto, CANADA, 2McGill University, CANADA, and 3Harbin Institute of Technology, CANADA

M2-250.e ON-DEMAND DIRECT CURRENT ELECTRIC FIELD IMMOBILIZATION ENABLES HIGH- RESOLUTION IMAGING OF C. ELEGANS Khaled Youssef1, Daphne Archonta1, Terrance J. Kubiseski1, Anurag Tandon2, and Pouya Rezai1 1York University, CANADA and 2University of Toronto, CANADA

T3-350.e CONTROLLING THE BODY ORIENTATION OF C. ELEGANS BY EXPLOITING ITS PROPRIOCEPTION IN A MICROFLUIDIC CONFINEMENT FOR BODY WALL MUSCLE IMAGING Samuel Sofela1,2, Sarah Sahloul1, Sukanta Bhattacharjee1, and Yong-Ak Song1,2 1New York University Abu Dhabi, UAE and 2New York University, USA

T3-351.e ON-DEMAND SAMPLE SELECTION AND BEHAVIORAL SCREENING OF ACTIVE MICROSWIMMERS ENABLED BY AN OPEN-ACCESSIBLE DEVICE Gongchen Sun, Cassidy-Arielle Manning, Ga Hyun Lee, and Hang Lu Georgia Institute of Technology, USA

T4-450.e EFFECT OF MICROFLUIDIC PROCESSING ON THE VIABILITY OF BOAR AND BULL SPERMATOZOA Tanja Hamacher1, Johanna T.W. Berendsen1, Stella A. Kruit1, Marleen L.W.J. Broekhuijse2,3, and Loes I. Segerink1 1University of Twente, THE NETHERLANDS, 2CRV, THE NETHERLANDS, and 3Topigs Norsvin, THE NETHERLANDS

T4-451.e PARALLEL SCREENING OF SINGLE ZOOSPORE GERMINATION AND GERM TUBE PROTRUSIVE FORCES Yiling Sun, Ayelen Tayagui, Ashley Garrill, and Volker Nock University of Canterbury, NEW ZEALAND

W5-550.e EGG LAYING NEURON MEDIATES ELECTROSENSATION IN CAENORHABDITIS ELEGANS Khaled Youssef1, Daphne Archonta1, Terrance J. Kubiseski1, Anurag Tandon2, and Pouya Rezai1 1York University, CANADA and 2University of Toronto, CANADA

W5-551.e STRAIGHTFORWARD MICROFLUIDIC SYSTEM FOR BEHAVIORAL RESPONSES ANALYSIS OF C. ELEGANS TO PHYSICAL CUES Sunhee Yoon, Tae-Joon Jeon, and Sun Min Kim Inha University, KOREA

W6-649.e HABITUATION OF ZEBRAFISH LARVAE TO ELECTRICAL STIMULUS Arezoo Khalili, Ellen van Wijngaarden, Georg Zoidl, and Pouya Rezai York University, CANADA

Th7-749.e ELECTRIC FIELD INDUCED C. ELEGANS EGG LAYING IS NEURON-MEDIATED AND DEPENDENT ON FIELD POLARITY Khaled Youssef1, Daphne Archonta1, Terrance J. Kubiseski1, Anurag Tandon2, and Pouya Rezai1 1York University, CANADA and 2University of Toronto, CANADA

Th8-849.e IN-VIVO QUANTIFICATION OF DROSOPHILA LARVA HEART FUNCTIONS Alireza Zabihihesari, Arthur J. Hilliker, and Pouya Rezai York University, CANADA

e - Cells, Organisms and Organs on a Chip Organs on Chip M1-152.e A MICROFLUIDIC MODEL OF THE HUMAN PLACENTA Taisei Amanokura, Takeshi Hori, Norio Kobayashi, Hiroaki Okae, Takahiro Arima, and Hirokazu Kaji Tohoku University, JAPAN

M1-153.e FABRICATION AND FLUIDIC INTEGRATION OF SELF-ASSEMBLED CELLULAR MICROTUBULES FOR NEPHRON-ON-CHIP APPLICATIONS Kevin Tröndle1, Ahmad Itani1, Fritz Koch1, Roland Zengerle1,2, Stefan Zimmermann1, and Peter Koltay1,2 1University of Freiburg, GERMANY and 2Hahn-Schickard, GERMANY

M1-154.e LAB-ON-A-CHIP SYSTEM INTEGRATED WITH NANOFIBER MATS FOR BIOCHEMICAL SIMULATION OF HYPOXIA OF CARDIAC CELLS Anna Kobuszewska, Dominik Kolodziejek, Michal Wojasiński, Tomasz Ciach, Zbigniew Brzózka, and Elżbieta Jastrzębska Warsaw University of Technology, POLAND

M1-155.e MODELLING SKIN PRO-INFLAMMATORY RESPONSE IN AN ENGINEERED INFECTED EPIDERMIS MODEL Maryam Jahanshai, Zhina Hadisi, and Mohsen Akbari University of Victoria, CANADA

M1-156.e WOUND-ON-A-CHIP DEVICE FOR HUMAN SKIN HEALING ASSAYS Kamil Talar1, Holly N. Wilkinson2, Alexander Iles1, Matthew J. Hardman2, and Nicole Pamme1 1University of Hull, UK and 2Hull York Medical School, UK

M2-251.e A MULTI-CULTURE ARRAY FOR MODELLING NUMEROUS MECHANISMS OF CUTANEOUS DRUG REACTIONS Lor Huai Chong1, Terry Ching1,2, Gianluca Grenci3, and Yi-Chin Toh1,4 1National University of Singapore, SINGAPORE, 2Singapore University of Technology and Design, SINGAPORE, 3Mechanobiology Institute, SINGAPORE, and 4Queensland University of Technology, AUSTRALIA

M2-252.e FROM MODEL SYSTEM TO THERAPY – SCALABLE PRODUCTION OF PERFUSABLE VASCULARIZED LIVER SPHEROIDS IN ''OPEN-TOP'' 384- WELL PLATE Dawn S.Y. Lin, Shravanthi Rajasekar, Mandeep Kaur Marway, and Boyang Zhang McMaster University, CANADA

M2-253.e LOW-COST OPEN MICROFLUIDIC DEVICE FOR VASCULARIZED SPHEROID-ON-A-CHIP Qinyu Li, Kai Niu, and Xiaolin Wang Shanghai Jiao Tong University, CHINA

M2-254.e MODELLING THE TUMOR MICRO-ENVIRONMENT IN HEPATOCELLULAR CARCINOMA USING MULTI-CELLULAR SPHEROIDS Ana Ortiz-Perez, Agnieszka Zuchowska, Jean-Baptiste Blondé, Ruchi Bansal, and Séverine Le Gac University of Twente, THE NETHERLANDS

T3-352.e A VASCULARIZED MICRO LIVER MODEL SUPPORTS ROBUST ALBUMIN AND CYP450 EXPRESSION BY HUMAN HEPATOCYTES Satomi Matsumoto, Jennifer S. Fang, Yu-Hsi Chen, Da Zhao, Abraham P. Lee, and Christopher C.W. Hughes University of California, Irvine, USA

T3-353.e HEART-LIVER ON A CHIP INTEGRATED WITH A MICROELECTRODE ARRAY TO MONITOR EXTRACELLULAR FIELD POTENTIALS OF CARDIOMYOCYTES Dongxiao Zhang1, Yoshikazu Hirai1, Ken-ichiro Kamei1, Osamu Tabata1,2, and Toshiyuki Tsuchiya1 1Kyoto University, JAPAN and 2Kyoto University of Advanced Science, JAPAN T3-354.e MEASURING BARRIER FUNCTION IN A GUT-ON-CHIP Elsbeth G.B.M. Bossink, Mariia Zakharova, Mathieu Odijk, and Loes Segerink University of Twente, THE NETHERLANDS

T3-355.e ON-CHIP MODELLING OF THE BIOPHYSICS OF PANCREATIC DUCTAL ADENOCARCINOMA FOR ASSESSMENT WITH NEW THERAPEUTICS Delanyo Kpeglo1, Margaret Knowles1, Malcolm Haddrick2, Stephen D. Evans1, and Sally A. Peyman1 1University of Leeds, UK and 2Medicines Discovery Catapult (MDC), UK

T4-452.e AN ELASTIC PROTEIN MEMBRANE FOR PERFUSABLE MICROFLUIDIC CELL BARRIER MODELLING IN A POLYDIMETHYLSILOXANE-FREE FLEXIBLE CHIP Lisa D. Muiznieks, Jessica Ayache, Emma Thomée, and Noémi Thomazo Elvesys - Microfluidics Innovation Center, FRANCE

T4-453.e HEMOSTASIS-ON-A-CHIP: EVALUATING THE EFFICACY OF THROMBIN-CONJUGATED IRON OXIDE NANOPARTICLES FOR PLATELET ACTIVATION IN ORGANOTYPIC BLOOD VESSELS Alexander F. Pessell, Kennedy R. Baugh, Anthony Geraci, Kayle Riley, Max M. Gong, and Melanie G. Watson Trine University, USA

T4-454.e MECHANICAL STIMULATION INCREASES ECM PRODUCTION BY CHONDROCYTES IN A CARTILAGE-ON-A-CHIP PLATFORM Carlo Alberto Paggi1, Jan Hendriks1, Liliana Moreira Teixeira1,2, Marcel Karperien1, and Séverine Le Gac1 1University of Twente, THE NETHERLANDS and 2Utrecht University, THE NETHERLANDS

T4-455.e ORAL MUCOSA-CHIP AS AN ALTERNATIVE PLATFORM TO EVALUATE THE IMPACTS OF DENTAL MONOMERS Khanh Ly1, Seyed Rooholghodos1, Christopher Rahimi1, Benjamin Rahimi1, Diane R. Bienek2, Gili Kaufman2, Christopher Raub1, and Xiaolong Luo1 1Catholic University of America, USA and 2ADA Science and Research Institute, USA

W5-552.e CANCER METASTASIS RECAPITULATED IN THREE-DIMENSIONAL HUMAN LIVER-CHIP Jooyoung Ro1,2, Junyoung Kim1,2, Chaeeun Lee1,2, and Yoon-Kyoung Cho1,2 1Ulsan National Institute of Science & Technology (UNIST), KOREA and 2Institute for Basic Science (IBS), KOREA

W5-553.e MEMS ACTUATION PROMOTES IN VITRO BRAIN-ON-CHIP MATURATION Alex Bastiaens1, Gulden Akcay1, Maaike Fransen1, Sijia Xie2, and Regina Luttge1 1Eindhoven University of Technology, THE NETHERLANDS and 2Paul Scherrer Institute, SWITZERLAND

W5-554.e RECONSTITUTING THE ARTERIAL INTIMA-MEDIA INTERFACE USING A DUAL-LANE EXTRACELLULAR MATRIX PATTERNED MICROFLUIDIC 3D CO-CULTURE PLATFORM FOR STUDY OF ATHEROSCLEROSIS Chengxun Su1, Nishanth Venugopal Menon1, Xiaohan Xu1, Yu Rong Teo1, Huan Cao1, Rinkoo Dalan1,2, Chor Yong Tay1, and Han Wei Hou1 1Nanyang Technological University, SINGAPORE and 2Tan Tock Seng Hospital, SINGAPORE

W6-650.e A 3D MICROPATTERNED NEURONAL CULTURE PLATFORM USING EXTRACELLULAR MATRIX-BASED HYDROGEL ON A MICROELECTRODE ARRAY Dongjo Yoon, Jaejung Son, Je-Kyun Park, and Yoonkey Nam Korea Advanced Institute of Science and Technology (KAIST), KOREA

W6-651.e CONTINUOUS MONITORING OF ISOGENIC BLOOD-BRAIN BARRIER INTEGRITY IN A PDMS-FREE MICROPHYSIOLOGICAL SYSTEM Thomas E. Winkler1, Isabelle Matthiesen1, Dimitrios Voulgaris1, Polyxeni Nikolakopoulou2, and Anna Herland1,2 1KTH Royal Institute of Technology, SWEDEN and 2Karolinska Institute, SWEDEN W6-652.e INTEGRATED ANISOTROPIC TUBULAR CARDIAC TISSUE AND CIRCULATING MICROCHANNEL SYSTEM FOR DRUG TESTING Bo-Heng (Henry) Liu and Fan-Gang Tseng National Tsing Hua University, TAIWAN

W6-653.e WITHDRAWN

W6-654.e SECRETOME ANALYSIS WITH SIMULTANEOUS ON-CHIP ANGIOGENESIS AND ANASTOMOSIS BETWEEN HUMAN ARTERIAL AND VENOUS CELLS Elisabeth Hirth1, Claudius Dietsche1, Todd Duncombe1, Danilo Ritz2, Maria Filippova2,3, and Petra S. Dittrich1 1ETH Zürich, Basel, SWITZERLAND, 2University of Basel, SWITZERLAND, and 3University Hospital, SWITZERLAND

Th7-750.e A 3D-PRINTED MODULAR MICROCHIP WITH AN INTEGRATED IMPELLER PUMP TO MODEL INTER-ORGAN COMMUNICATION Sophie R. Cook and Rebecca R. Pompano University of Virginia, USA

Th7-751.e DEVELOPMENT OF CLOSED AND PUMPLESS PLATFORM FOR CO-CULTURE IN MINIMALIZED SPACE Hidetaka Ueno1,2, Yuri Aoki3, Kenji Hanamura3, Mai Yamamura3, Tomoaki Shirao3, and Takaaki Suzuki3 1National Institute of Advanced Industrial Science and Technology (AIST), JAPAN, 2JSPS Research Fellow, JAPAN, and 3Gunma University, JAPAN

Th7-752.e INTEGRATING PANCREAS TISSUE SLICES WITH ADVANCED ANALYTICAL APPROACHES FOR MEASUREMENT OF INSULIN RELEASE I-An Wei and Michael G. Roper Florida State University, USA

Th7-753.e MICROFLUIDICS AND IMMUNOTHERAPY: MODELLING SOLID TUMORS Jose M. Ayuso, Maria Virumbrales-Munoz, Patrick H. McMinn, Shujah Rehman, Cate M. Fitzgerald, Melissa C. Skala, and David J. Beebe University of Wisconsin, USA

Th7-754.e SOFT STRETCHABLE BIOLOGICAL MEMBRANES FOR ORGANS-ON-CHIP Pauline Zamprogno1, Giuditta Thoma1, Veronika Cencen2, Dario Ferrari1, Barbara Putz3, Johann Michler3, Georg E. Fantner2, and Olivier T. Guenat1,4 1University of Bern, SWITZERLAND, 2Ecole Polytechnique Fédérale de Lausanne (EPFL), SWITZERLAND, 3EMPA Swiss Federal Laboratories for Materials Science and Technology, SWITZERLAND, and 4University Hospital of Bern, SWITZERLAND

Th8-850.e A LIVER-IN-CHIP PLATFORM FOR PRESERVING EX VIVO TISSUE VIABILITY Foivos Chatzidimitriou, Soon Seng Ng, S. Tamir Rashid, Joseph M. Sherwood, and Darryl R. Overby Imperial College London, UK

Th8-851.e EFFECT OF SHEAR STRESS ON THE EXPRESSION OF FUNCTIONAL PROTEINS IN A BILAYER PROXIMAL TUBULE-ON-A-CHIP Ramin Banan Sadeghian1, Ryohei Ueno1, Toshikazu Araoka1, Jun Yamashita1, Tatsuji Enoki2, Minoru Takasato3, and Ryuji Yokokawa1 1Kyoto University, JAPAN, 2Takara Bio, Inc., JAPAN, and 3RIKEN, JAPAN

Th8-852.e INVESTIGATING DRUG-INDUCED AUTOPHAGY IN A MICROFLUIDIC MODEL OF GLIOBLASTOMA Ehsan Samiei1, Saeid Ghavami2, and Mohsen Akbari1 1University of Victoria, CANADA and 2University of Manitoba, CANADA

Th8-853.e MICROPILLAR-BASED MICROFLUIDIC SYSTEM FOR STUDIES OF 3D PANCREATIC ISLET STRUCTURES Patrycja Sokolowska1,2, Anna Grabowska1, Kamil Żukowski1, Elzbieta Jastrzebska1, Zbigniew Brzozka1, and Agnieszka Dobrzyn2 1Warsaw University of Technology, POLAND and 2Nencki Institute of Experimental Biology, POLAND

Th8-854.e SYNOVIAL MEMBRANE ON CHIP: A NEW TOOL TO STUDY CO-CULTURE RESPONSE TO MECHANICAL STIMULATION Carlo Alberto Paggi1, Mariia Zakharova1, Loes Segerink1, Séverine Le Gac1, Liliana Moreira-Teixeira1,2, and Marcel Karperien1 1University of Twente, THE NETHERLANDS and 2Utrecht University, THE NETHERLANDS

e - Cells, Organisms and Organs on a Chip Bioinspired, Biomimetic & Biohybrid Devices M1-157.e FORMATION OF A NEURON-MUSCLE CONSTRUCT USING NEURAL CELL FIBERS AND SKELETAL MUSCLE TISSUE FOR BIOHYBRID ACTUATORS Akihiro Sunagawa1, Midori Negishi1,2, Minghao Nie1, Yuya Morimoto1, and Shoji Takeuchi1 1University of Tokyo, JAPAN and 2Musashino University, JAPAN

M2-255.e A NEW PLATFORM FOR CULTURE AND ELECTROPORATION OF 3D CELL CONSTRUCTS BASED ON A POROUS SCAFFOLD Marie Frénéa-Robin, Julien Marchalot, Laure Franqueville, and Charlotte Rivière University of Lyon, FRANCE

M2-256.e RECAPITULATING CYCLIC STRETCH IN MICROVASCULATURE BY FLOW-INDUCED CUES IN HYDROGEL MICROCHANNELS Walter Varhue, Aditya Rane, Shayn Peirce-Cottler, George Christ, and Nathan S. Swami University of Virginia, USA

T3-356.e ACTOMYOSIN-COLLAGEN HYBRID SOFT ACTUATOR Kenjiro Kohno1, Shusei Kawara1, Yuichi Hiratsuka2, and Hiroaki Onoe1 1Keio University, JAPAN and 2Japan Advanced Institute of Science and Technology (JAIST), JAPAN

T3-357.e THE INFLUENCE OF SHEAR STRESS GENERATED BY OSMOTIC DRIVEN FLOW ON THE ALIGNMENT OF ENDOTHELIIAL CELL Zong-Han Sie1, Lu-Wei Wu1, Yen-Yu Chang1, Yi-Chin Toh2, and Ya-Yu Chiang1 1National Chung-Hsing University, TAIWAN and 2Queensland University of Technology, AUSTRALIA

T4-456.e ANTI-BIOFOULING SURFACES FEATURED WITH MAGNETIC ARTIFICIAL CILIA Shuaizhong Zhang1, Pan Zuo1, Ye Wang1, Patrick R. Onck2, and Jaap M.J. den Toonder1 1Eindhoven University of Technology, THE NETHERLANDS and 2University of Groningen, THE NETHERLANDS

W5-555.e ZINC OXIDE NANOPILLARS INHIBIT BACTERIAL ATTACHMENT Nicholas Lin, Amin Valiei, Nathalie Tufenkji, and Christopher Moraes McGill University, CANADA

W6-655.e CELL-BASED SENSOR INTEGRATED IN OPTICAL FIBER TOWARD MONITORING OF NEUROTRANSMITTERS Hisashi Shimizu1, Yuichi Morohashi2, Yoko Yazaki-Sugiyama1,2, and Shoji Takeuchi1 1University of Tokyo, JAPAN and 2Okinawa Institute of Science and Technology Graduate University, JAPAN

Th7-755.e CROSSLINKING AEROSOL-BASED MULTI-BIOINK PRINTING SYSTEM TO CONSTRUCT HETEROGENEOUS AND MULTILAYERED HYDROGELS Gihyun Lee, Soo Jee Kim, and Je-Kyun Park Korea Advanced Institute of Science and Technology (KAIST), KOREA

Th8-855.e EXOSKELETAL BIOHYBRID ROBOT USING ANTAGONISTIC XENOPUS MUSCLE Jinhwa Lee1, Yuya Morimoto1, Masahiro Shimizu2, and Shoji Takeuchi1 1University of Tokyo, JAPAN and 2Osaka University, JAPAN

e - Cells, Organisms and Organs on a Chip Synthetic Biology T4-457.e CELL-FREE LOW-COST DE NOVO BACTERIOPHAGE GENOME SYNTHESIS FROM SEQUENCE-VERIFIED MICROARRAY-SYNTHESIZED DNA OLIGONUCLEOTIDES Huiran Yeom1v, Taehoon Ryu2, Namphil Kim1, and Sunghoon Kwon1 1Seoul National University, KOREA and 2Celemics, Inc, KOREA

W5-556.e DNA NANOBALL RETRIEVAL MICROCHIP DESIGN FOR HIGH-THROUGHPUT ERROR-FREE DNA PURIFICATION PLATFORM Namphil Kim, Huiran Yeom, Yonghee Lee, and Sunghoon Kwon Seoul National University, KOREA

W6-656.e DROPLET MICROFLUIDIC MICROCOLONY SORTING BY FLUORESCENCE AREA FOR HIGH THROUGHPUT, YIELD-BASED SCREENING OF TRIACYL GLYCERIDES IN S. CEREVISIAE Sara M. Björk, Martin Schappert, and Haakan N. Joensson KTH Royal Institute of Technology, SWEDEN

Th7-756.e INTRACELLULAR SENSING OF EXPRESSED FACTORS BY REDOX AMPLIFICATION USING BIO-CAPACITOR ON NANOPOROUS GOLD Yi Liu, John H. Moore, and Nathan S. Swami University of Virginia, USA

Th8-856.e RT-OGENE: A REAL-TIME OPTOGENETICS SYSTEM FOR CONTROLLING GENE EXPRESSION USING MODEL-BASED DESIGN James M. Perry, Guy Soffer, and Steve C.C. Shih Concordia University, CANADA

e - Cells, Organisms and Organs on a Chip Liposomes/Membranes M1-158.e AN APROTIC POLAR SOLVENT ASSISTED SIZE-TUNING METHOD FOR MICROFLUIDIC PRODUCTION OF LIPID-BASED DRUG NANOCARRIERS WITH VARIOUS SIZES Niko Kimura, Masatoshi Maeki, Akihiko Ishida, Hirofumi Tani, and Manabu Tokeshi Hokkaido University, JAPAN

M2-257.e MICROFLUIDIC FORMATION OF LIPID-OUT ASYMMETRIC DROPLET INTERFACE BILAYERS FOR ON-CHIP PHARMACOKINETICS MODELLING Elanna B. Stephenson and Katherine S. Elvira University of Victoria, CANADA

T3-358.e PLASMONIC STRUCTURES FOR CLINICAL-SCALE EXOSOME ANALYSIS Felix Kurth, Luc Driencourt, Fabian Lütolf, Rolando Ferrini, and Silvia Generelli CSEM, SWITZERLAND

T4-458.e THE BOTTOM-UP SYNTHESIS OF BESPOKE PROTOTISSUES USING A MICROFLUIDIC PLATFORM Kaitlyn E. Ramsay1, Jae F. Levy1, Pierangelo Gobbo2, and Katherine Elvira1 1University of Victoria, CANADA and 2University of Bristol, UK

e - Cells, Organisms and Organs on a Chip Other Applications in Biology W5-557.e AN ACOUSTIC-ELECTRICAL SHEAR OPENING PORATION (AESOP) PLATFORM FOR INTRACELLULAR DELIVERY Yu-Hsi Chen, Mohammad Aghaamoo, and Abraham P. Lee University of California, Irvine, USA

W6-657.e DEVELOPMENT OF NOVEL SCREENING PLATFORM AND ORGANOID CULTURE MODEL FOR QUANTIFIABLE HIGH THROUGHPUT SCREENING OF TUMOR ORGANOID Yong Hun Jung1, Donghee Choi1, Kyungwon Park1, Satbyol Lee3, Hyunwoo Chung1, Jihun Yang1, Jinah Kim1, Byungsoh Min3, and Seok Chung1,2 1Korea University, KOREA, 2Korea Institute of Science and Technology (KIST), KOREA, and 3Yonsei University College of Medicine, KOREA

Th7-757.e MICROFLUIDIC INTRACELLULAR DELIVERY VIA FLUID CELL SHEARING GeoumYoung Kang, Chan Kwon, and Aram Chung Korea University, KOREA

Th8-857.e ORGANOSILICON INTERACTION WITH BIOLOGICAL MEMBRANES Pepijn Beekman1, Agustin Enciso-Martinez1, Sidharam Pujari2, Han Zuilhof2, Leon Terstappen1, Cees Otto1, and Séverine Le Gac1 1University of Twente, THE NETHERLANDS and 2Wageningen University, THE NETHERLANDS

e - Cells, Organisms and Organs on a Chip Industrial Benefactor W6-658.e CUSTOMIZABLE MICROFLUIDIC DEVICES FOR CO-CULTURE AND ALI RECREATION: BE- DOUBLEFLOW & BE-TRANSFLOW Sandra González Lana1,2, Lara Pancorbo Lambán1, Sara Aldea Martín1, Luis E. Serrano Ramón1, and Rosa M. Monge Prieto1 1BEOnChip S.L., SPAIN and 2University of Zaragoza, SPAIN

Th8-879.e NOURISHING, MONITORING AND STIMULATING CELLS WITH BI/OND’S ORGAN-ON-CHIP DEVICE Amr Othman1, Lucie Decourt1, William. F. Quiros-Solano1, Dik C. van Gent2, Sanjiban Chakrabarty3, Cinzia Silvestri1, and Nikolas Gaio1 1BIOND Solutions B.V., THE NETHERLANDS, 2Erasmus Medical Centre, THE NETHERLANDS, and 3Manipal Academy of Higher Education, INDIA

M1-182.e A USER-FRIENDLY MICROFLUIDICS PLATFORM FOR HIGH-CONTENT IMAGING OF SMALL MODEL ORGANISMS FOR ASSESSMENT OF CHEMICAL TOXICITY Evan M. Hegarty, Adam F. Laing, Adela Ben-Yakar Newormics LLC, USA

T4-483.e RESEALABLE, RECIRCULATING PLATFORM FOR THE MECHANICAL STIMULATION OF CELL CO-CULTURES IN A TRANSWELL INSERT Sandro Meucci1, Jasper ten Napel1, Bianka Fabinyi1, Astrid D. Bakker2, Lasse Jensen3, and Anna Fahlgren4 1Micronit Microtechnologies BV, THE NETHERLANDS, 2Academisch Centrum Tandheelkunde Amsterdam (ACTA), THE NETHERLANDS, 3BioReperia, SWEDEN, and 4Linköping University, SWEDEN

e - Cells, Organisms and Organs on a Chip Late News M1-180.e REAL-TIME OPTICAL MONITORING OF CELL CULTURE IN CENTRIFUGAL MICROFLUIDICS Edwin En-Te Hwu1, Lina Gruzinskyte1,3, Atsushi Ishimoto1,2, Laura Serioli1, Sriram Thoppe Rajendran1, Akinobu Yamaguchi2, Kinga Zór1, and Anja Boisen1 1Technical University of Denmark, DENMARK, 2University of Hyogo, JAPAN, and 3University of Copenhagen, DENMARK

M2-278.e A MICROFLUIDIC CHIP FOR MEASURING WHITE BLOOD CELL CONCENTRATION FROM AN UNDILUTED, WHOLE BLOOD Georgia Korompili1, Katerina Skorda1, and Nikos Chronis1,2 1National Centre of Scientific Research (NCSR) Demokritos, GREECE and 2University of Crete, GREECE

M2-279.e A MICROFLUIDIC SYSTEM FOR INVESTIGATING THE TRANSIT DYNAMICS OF LIVE AND HEAT-KILLED E. COLI BACTERIA IN C. ELEGANS Vittorio Viri, Thomas Lehnert, and Martin A.M. Gijs École Polytechnique Fédérale de Lausanne (EPFL), SWITZERLAND

T3-379.e 3D VASCULAR NETWORKS CO-CULTURED WITH VARIOUS TYPES OF COLORECTAL CANCER CELLS FOR VALIDATION OF NATURAL KILLER CELL CYTOTOXICITY Hyeri Choi, Jiyoung Song, Dohyun Park, and Noo Li Jeon Seoul National University, KOREA

T3-380.e HIGH-RESOLUTION AND MASSIVE TRAPPING AND SEPARATION OF BACTERIA AND NANOPARTICLES IN AN OPTOFLUIDIC CHIP Yuzhi Shi, Yi Zhang, Yang Liu, Shilun Feng, Wee Ser, Peng Huat Yap, and Ai Qun Liu Nanyang Technological University, SINGAPORE

T4-479.e EVALUATION OF PLURIPOTENCY IN HUMNAN INTENSTINAL CELLS BY MICROFLUIDIC- BASED SINGLE CELL DEFORMABILITY ANALYSIS Miyu Terada1, Sachiko Ide1, Toyohiro Naito1, Michiya Matsusaki2, and Noritada Kaji1 1Kyushu University, JAPAN and 2Osaka University, JAPAN

T4-480.e MICROFLUIDIC COLLAGEN PATTERNING FOR TENDON REGENERATION Francesca Giacomini, David B. Barata, Hoon Suk Rho, Zeinab Tahmasebi Birgani, Stefan Giselbrecht, Roman Truckenmüller, and Pamela Habibović Maastricht University, NETHERLANDS

W5-578.e HIGHLY PARALLEL SINGLE-CELL SIMULTANEOUS TRANSCRIPTOME AND PROTEIN ANALYSIS Xing Xu, Mingxia Zhang, Xuebing Zhang, Zhi Zhu, and Chaoyong Yang Xiamen University, CHINA

W5-579.e MICROPHYSIOLOGICAL MODEL OF ENDOTHELIUM-FIBROBLAST INTERFACE FOR INVESTIGATING WOUND HEALING Halston E. Deal1,2, Ashlyn T. Young1,2, Ashley C. Brown1,2, and Michael A. Daniele1,2 1North Carolina State University, USA and 2University of North Carolina, Chapel Hill, USA

W6-679.e DNA HYDROGELS AS A SCAFFOLD FOR ORGANS-ON-CHIPS: STUDY OF BUOYANCY AND SEDIMENTATION OF MICROBEADS IN DNA GELS Emilie Belot1,2, Yannick Tauran1,2, Yusuke Sato3, Masahiro Takinoue4, Arnaud Brioude1, Teruo Fujii2, and Anthony J. Genot2 1Université de Lyon, FRANCE, 2University of Tokyo, FRANCE, 3Tohoku University, JAPAN, and 4Tokyo Institute of Technology, JAPAN

W6-680.e RECONSTRUCTION OF 3D HUMAN LYMPHATIC VESSEL WITHIN TUMOR IMMUNE MICROENVIRONMENT USING HIGH-THROUGHPUT PLATFORM Habin Kang1, Somin Lee1, Dohyun Park1, James Yu1, Seung Kwon Koh2, Duck Cho2, Da-Hyun Kim1, Kyung-Sun Kang1, and Noo Li Jeon1 1Seoul National University, KOREA and 2Sungkyunkwan University, KOREA

Th7-778.e A HYDROGEL CO-CULTURE PLATFORM REVEALS COMMUNITY RESPONSES OF BACTERIA TO ALGAL HOST AND NUTRIENTS UNDER A DIFFUSION-CONTROLLED ENVIRONMENT Hyungseok Kim1, Jeffrey A. Kimbrel2, Jessica Wollard2, Xavier Mayali2, and Cullen R. Buie1 1Massachusetts Institute of Technology, USA and 2Lawrence Livermore National Laboratory, USA

Th7-779.e TOWARDS HYBRID BIOPRINTING AIDED LIVER ON CHIP Muhammad Asim Faridi, Zofia Korczak, Philip Dalsbecker, and Caroline B. Adiels Gothenburg University, SWEDEN

Th8-876.e MICROGROOVE GUIDED 2D CELL CULTURE APPLIED TO CONSTRUCT 3D SEMI-SPHERICAL HEART PUMPING SYSTEM Bo-Heng (Henry) Liu, Guan-You Shih, and Fan-Gang Tseng National Tsing Hua University, TAIWAN

Th8-877.e THERMAL MORPHOGENESIS IN TISSUE-LIKE ARRAYS OF DROPLETS Nicolas Lobato-Dauzier1, Robin Deteix1, Shu Okumura1, Alexandre Baccouche1, Guillaume Gines2, Yannick Rondelez2, Teruo Fujii1, and Anthony J. Genot1 1University of Tokyo, JAPAN and 2PSL Research University, FRANCE

f - Diagnostics, Drug Testing & Personalized Medicine Liquid Biopsy and Sample Preparation M1-159.f ISOLATION OF ALZHEIMER'S DISEASE ASSOCIATED EXOSOMES USING GRAPHENE OXIDE-BASED MICROFLUIDIC CHIP WITH PREFIBRILLAR AMYLOID β (AβExoChip) Yoon-Tae Kang, Ji-Young Kim, Thomas Hadlock, Andrew Rellinger, Nicholas Kotov, and Sunitha Nagrath University of Michigan, Ann Arbor, USA

M2-258.f CHARACTERIZATION OF EXTRACELLULAR VESICLES PURIFIED BY ULTRACENTRIFUGATION, SIZE-EXCLUSION CHROMATOGRAPHY AND LAB-ON-A-DISC FILTRATION Lucile Alexandre1,2, Philippe DeCorwin-Martin1, Rosalie Martel1, Molly Shen1, Johan Renault1, Lorenna Oliveira1, Andy Ng1, and David Juncker1 1McGill University, CANADA and 2Institut Curie, FRANCEe

M2-259.f MOLECULAR AND FUNCTIONAL EXTRACELLULAR VESICLE ANALYSIS USING NANOPATTERNED MICROCHIPS MONITORS TUMOR PROGRESSION AND METASTASIS Peng Zhang1,2, Chaoyong Yang2, and Yong Zeng1 1University of Kansas, USA and 2Shanghai Jiaotong University School of Medicine, CHINA

T3-359.f DETERMINISTIC LATERAL DISPLACEMENT FOR THE SORTING OF EXTRACELLULAR VESICLES FROM COMPLEX BIOLOGICAL SAMPLES Marie Gaillard1, Nicolas Sarrut-Rio1, Léopold Virot1, François Boizot1, Nicolas Verplanck1, Camille Raillon1, Vincent Agache1,2, Yoann Roupioz1, and Aurélie Thuaire1 1University Grenoble Alpes, FRANCE and 2Massachusetts Institute of Technology, USA

T3-360.f PRECISELY METERED DRIED BLOOD SPOTS BY USING TUNABLE HYDROPHOBIC BURST VALVES Lorenz Van Hileghem, Dries Vloemans, Francesco Dal Dosso, and Jeroen Lammertyn KU Leuven, BELGIUM

T4-459.f EFFICIENT HUMAN PLASMA EXTRACTION FROM UNDILUTED WHOLE BLOOD BY CELL- FREE LAYER MARGINATION WITH CLOSED-LOOP SINGLE MICROFLUIDIC CHANNEL DEVICE Lap Man Lee, Ketan H. Bhatt, Dustin W. Haithcock, Mary A. Arugula, Balabhaskar Prabhakarpandian, and Kapil Pant CFD Research Corporation, USA

T4-460.f TEM GRID PREPARATION WITH MINIMAL USER INTERACTION Janosch Hauser1, Gustaf Kylberg2, Göran Stemme1, Ida-Maria Sintorn2, and Niclas Roxhed1 1KTH Royal Institute of Technology, SWEDEN and 2Vironova AB, SWEDEN

W5-558.f EXOSOME ISOLATION VIA CLICK CHEMISTRY (EXOCLICK) CHIP FOR SCREENING AND QUANTIFICATION OF CANCER-ASSOCIATED EXOSOMES Yoon-Tae Kang, Thomas Hadlock, Shruti Jolly, and Sunitha Nagrath University of Michigan, Ann Arbor, USA

W6-659.f EXTRACELLULAR VESICLE DETECTION DIRECTLY IN COMPLEX MATRICES BY USING FO- SPR SENSOR Yagmur Yildizhan1, Venkata Suresh Vajrala1, Charles Declerck1, Edward Geeurickx2, Sam Noppen1, Dominique Schols1, Johannes V. Swinnen1, Sven Eyckerman2, An Hendrix2, Jeroen Lammertyn1, and Dragana Spasic1 1KU Leuven, BELGIUM and 2Gent University, BELGIUM

Th7-758.f HARVESTING BIOMOLECULES FROM TISSUE BY POROUS SILICON NANONEEDLES Davide A. Martella and Ciro Chiappini King's College London, UK

Th8-858.f INKJET-PRINTED 3D NANO-ENGINEERED MICROCHIPS FOR FUNCTIONAL ANALYSIS OF METASTATIC EXOSOMES Yong Zeng1, Peng Zhang2, and Liang Xu2 1University of Florida, USA and 2University of Kansas, USA

f - Diagnostics, Drug Testing & Personalized Medicine Nucleic-Acid Analysis M1-160.f EVALUATION OF DLP 3D PRINTING MATERIALS FOR THE MANUFACTURE OF RECOMBINASE POLYMERASE AMPLIFICATION (RPA) MICROREACTORS Ole Behrmann1,2, Matthias Hügle1,2, Franz Eckardt1, Iris Bachmann1, Frank T. Hufert1, and Gregory Dame1 1Brandenburg Medical School Theodor Fontane, GERMANY and 2University of Freiburg, GERMANY

M2-260.f METAL OXIDE NANOWIRES MICROFLUIDIC DEVICES FOR DNA METHYLATION MAPPING Marina Musa1, Takao Yasui1,2, Taisuke Shimada1, Akihide Arima1, and Yoshinobu Baba1,3 1Nagoya University, JAPAN, 2Japan Science and Technology Agency (JST), JAPAN, and 3National Institutes for Quantum and Radiological Science and Technology, JAPAN

T3-361.f MICRORNA DETECTION USING STRAND DISPLACEMENT AMPLIFICATION IN HYDROGEL PARTICLES Nidhi Juthani and Patrick S. Doyle Massachusetts Institute of Technology, USA

T4-461.f NAKED-EYE DETECTION OF POLYMERASE CHAIN REACTION ON MICROFLUIDICS Ren Shen1, Yanwei Jia1, Pui-In Mak1, and Rui P. Martins1,2 1University of Macau, CHINA and 2Universidade de Lisboa, PORTUGAL

W5-559.f AUTOMATION OF THE PAPER-BASED VERTICAL FLOW PLATFORM FOR RADIATION BIODOSIMETRY DURING DEEP SPACE MISSION Jasmine P. Devadhasan, Paul Kuehl, Jerome Lacombe, Jana Stoudemire, Twyman Clements, Jian Gu, and Frederic Zenhausern University of Arizona, College of Medicine, USA

W5-560.f OE-PCR IN DROPLETS FOR RAPID CONVERSION OF ANTIBODY LIBRARIES Micaela Vitor1, Lucas Pereira2, Guillaume Mottet1, Emmanuelle Vigne1, and Melody Shahsavarian1 1Sanofi, FRANCE and 2L’École Supérieure de Physique et de Chimie Industrielles (ESPCI)FRANCE

W6-660.f CENTRIFUGAL MICROFLUIDIC 4-PLEX DIGITAL DROPLET PCR FOR QUANTIFICATION OF CIRCULATING TUMOR DNA Franziska Schlenker1, Elena Kipf1, Nadine Borst1,2, Tobias Hutzenlaub1,2, Nils Paust1,2, Roland Zengerle1,2, Felix von Stetten1,2, and Peter Juelg1 1Hahn-Schickard, GERMANY and 2University of Freiburg, GERMANY

W6-661.f REAGENT INTEGRATION IN DISPOSABLE THERMOPLASTIC 2D MICROWELL ARRAYS USING A CUSTOM SPOTTING PIN Supriya Padmanabhan, Micaela Everitt, Michael Yeh, Ian White, and Don L. DeVoe University of Maryland, College Park, USA

Th7-759.f COMPLEX NUCLEIC ACID HYBRIDIZATION REACTIONS INSIDE CAPILLARY-DRIVEN MICROFLUIDIC CHIPS Marie L. Salva1,2, Marco Rocca1,2, Yong Hu1, Emmanuel Delamarche2, and Christof M. Niemeyer1 1Karlsruhe Institute of Technology, GERMANY and 2IBM Research Europe, SWITZERLAND

Th7-760.f UNRAVELLING THE REACTION MECHANISM AND KINETICS OF DNAZYMES BASED ON BULK AND SINGLE MOLECULE STUDIES Aida Montserrat Pagès1, Phebe De Keyser1, Victor Top1, Rebecca Andrews2, Maarten Hertog1, Achillefs N. Kapanidis2, Dragana Spasic1, and Jeroen Lammertyn1 1KU Leuven, BELGIUM and 2Oxford University, UK

Th8-859.f DIGITAL AND MULTIPLEX MICRO RNA DETECTION WITH MICROCOMPARTMENTALIZED BEAD ASSAY Thomas Jet1, Guillaume Gines2, Alexis Moravic2, Yannick Rondelez2, and Valérie Taly1 1Université de Paris, FRANCE and 2ESPCI Paris, FRANCE

f - Diagnostics, Drug Testing & Personalized Medicine Protein Analysis & Proteomics M1-161.f AUTOMATING NANODROPLET SAMPLE PREPARATION WITH LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY FOR HIGH THROUGHPUT SINGLE-CELL PROTEOMICS Ying Zhu Pacific Northwest National Laboratory, USA

M1-162.f TIME-RESOLVED MICROFLUIDIC SAMPLE PREPARATION FOR CRYO-EM STRUCTURAL ANALYSIS OF BIOMOLECULAR ASSEMBLIES Byungjin Lee1, Märt-Erik Mäeots2, Dong-Ho Kim1, Kyung Han Kim1, Sung Sik Lee3, Radoslav E. Ivanov2, Matthias Peter3, and Chang-Soo Lee1 1Chungnam National University, KOREA, 2ETH Zürich, SWITZERLAND, and 3Francis Crick Institute, UK

M2-261.f BIOASSAY ARCHITECTURE COMBINING A QUANTITATIVE G6PDH ASSAY AND A MEASUREMENT OF HEMOGLOBIN CONCENTRATION ON A SINGLE CAPILLARY-DRIVEN MICROFLUIDIC CHIP Marco Rocca1,2, Yuksel Temiz1, Marie L. Salva1,2, Samuel Castonguay3, Thomas Gervais3, Christof M. Niemeyer2, and Emmanuel Delamarche1 1IBM Research Europe, SWITZERLAND, 2Karlsruhe Institute of Technology (KIT), GERMANY, and 3École Polytechnique de Montréal (EPM), CANADA

T3-362.f DETECTION OF MULTIPLE SEPSIS BIOMARKERS USING A MICROFLUIDIC FLOW CYTOMETER Xilong Yuan1, Todd Darcie1, Srishti Garg1, James Dou2, Lu Chen2, and J. Stewart Aitchison1 1University of Toronto, CANADA and 2Thinkari Research Inc., CANADA

T4-462.f DROPLET MICROFLUIDICS BASED ENZYMATIC DIGESTION: A NEW SAMPLE PREPARATION TOOL FOR MALDI-TOF MS Mathilde Richerd1, Sarah Bregant2, Florent Malloggi2, and Stéphanie Descroix1 1Institut Curie, FRANCE and 2Université Paris-Saclay, FRANCE

W5-561.f ELISA UTILIZING THIN-LAYERED CHANNEL FOR PERFECT CAPTURE AND ACCUMULATION OF TARGET MOLECULE Ryoichi Ohta1, Keisuke Sekiya1, Smirnova Aderina1, Emi Mori1, and Takehiko Kitamori1,2 1University of Tokyo, JAPAN and 2National Tsing Hua University, TAIWAN

W6-662.f PICO-LITER PROTEIN DIGESTION AND SEPARATION USING NANOFLUIDIC DEVICE Kyojiro Morikawa1, Koki Yamamoto1, Hiroki Sano1, Yutaka Kazoe2, Hisashi Shimizu1, Hiroyuki Imanaka3, Koreyoshi Imamura3, and Takehiko Kitamori1,4 1University of Tokyo, JAPAN, 2Keio University, JAPAN, 3Okayama University, JAPAN, and 4National Tsing Hua University, TAIWAN

Th7-761.f IN SITU NMR LAB-ON-A-CHIP SYSTEM FOR STUDYING PROTEIN-LIGAND INTERACTIONS Marek Plata, William Hale, Manvendra Sharma, Jörn M. Werner, and Marcel Utz University of Southampton, UK

Th8-860.f AUTOMATED CHIP-BASED THIN-LAYERED ELISA Adelina Smirnova1, Ryoichi Ohta1, and Takehiko Kitamori2 1University of Tokyo, JAPAN and 2National Tsing Hua University, TAIWAN

Th8-861.f LOCALIZED MULTIPLEXED SURFACE FUNCTIONALIZATION OF THERMOPLASTIC MICROCHANNELS TOWARDS THE ENRICHMENT AND PROTEIN CARGO ANALYSIS OF EXTRACELLULAR VESICLES André Kling, Yannick R.F. Schmid, Jonas Nikoloff, and Petra S. Dittrich ETH Zürich, SWITZERLAND f - Diagnostics, Drug Testing & Personalized Medicine Cancer Research, Capture & Analysis of Circulating Tumor Cells M1-163.f PATIENT-DERIVED KIDNEY CANCER MODELS ON-A-CHIP TO INFORM PRECISION ONCOLOGY Maria Virumbrales-Muñoz, Jiong Chen, Jose Ayuso, E. Jason Abel, and David J. Beebe University of Wisconsin, Madison, USA

M2-262.f A BIO-MICROCHIP FUNCTIONALIZED BY SELF-ASSEMBLED AUNPS FOR EFFICIENT CAPTURE AND RELEASE OF CIRCULATING TUMOR CELLS Yixing Gou1,2, Zheng You2, Changku Sun1, and Dahai Ren1 1Tianjin University, CHINA and 2Tsinghua University, CHINA

M2-263.f QUANTIFICATION OF PROTEIN EXPRESSION LOCALLY ON FROZEN TISSUE SECTIONS TO EVALUATE TUMOR HETEROGENEITY Anna Fomitcheva Khartchenko1,2, Peter Schraml3, and Govind V. Kaigala2 1ETH Zürich, SWITZERLAND, 2IBM Research – Europe, SWITZERLAND, and 3University Hospital Zurich, SWITZERLAND

T3-363.f ACOUSTIC MICROSTREAMING CAPTURE OF CIRCULATING TUMOR CELLS AND CIRCULATING CANCER ASSOCIATED FIBROBLASTS AND FUNCTIONAL IMMUNE ASSESSMENT FROM BREAST CANCER PATIENTS Ruoyu Jiang, Sudhanshu Agrawal, Ritesh Parajuli, Anshu Agrawal, and Abraham P. Lee University of California, Irvine, USA

T3-364.f SACA CHIP ENABLED CIRCULATING TUMOR CELL CLUSTERS PHENOTYPING FOR CANCER IMMUNOTHERAPY RESPONSE MONITORING Chun-Jieh Hsu1, Yu-Chia Kan2, Chun-Wei Lee1, Jen-Kuei Wu1,2, Kang-Yun Lee3, Po-Hao Feng3, Wei-Chiao Chang3, and Fan-Gang Tseng1,2 1National Tsing Hua University, TAIWAN, 2Academia Sinica, TAIWAN, and 3Taipei Medical University, TAIWAN

T4-463.f CREATING AN IN VITRO LUNG MICROENVIRONMENT VIA DNA-DIRECTED PATTERNING TO INVESTIGATE THE ROLE OF EXTRACELLULAR VESICLES IN METASTASIS Sean E. Kitayama and Lydia L. Sohn University of California, Berkeley, USA

T4-464.f TUMOR-AGNOSTIC MICROFLUIDIC ISOLATION OF CIRCULATING TUMOR CELLS FROM LEUKAPHERESIS PRODUCTS Avanish Mishra1,2, Taronish D. Dubash1,2, Jon F. Edd1, Michelle Jewett1, Suhaas G. Garre1, Nezihi Murat Karabacak1,3, Daniel C. Rabe1,2, Baris R. Mutlu1,2, John R. Walsh1, Ravi Kapur4, Shannon L. Stott1,2, Shyamala Maheswaran1,2, Daniel A. Haber1,2,5, and Mehmet Toner1,2,3 1Massachusetts General Hospital, USA, 2Harvard Medical School, USA, 3Shriners Hospitals for Children, USA, 4MicroMedicine, Inc., USA, 5Howard Hughes Medical Institute, USA

W5-562.f HIERARCHICAL HERRINGBONE MICROWELLS FOR HIGH-THROUGHPUT SINGLE CELL ENTRAPMENT Ayoub Glia1,2, Pavithra Sukumar1, Muhammedin Deliorman1, and Mohammad A. Qasaimeh1,2 1New York University Abu Dhabi, UAE and 2New York University, USA

W5-563.f WHOLE GENOME SEQUENCING OF SINGLE CIRCULATING TUMOR CELLS AFTER THEIR SIZE-BASED ENRICHMENT Wooseok Lee, Amos Chungwon Lee, Yongju Lee, Ahyoun Choi, Sudeok Kim, and Sunghoon Kwon Seoul National University, KOREA

W6-663.f MICRODISSECTED TUMOR TISSUE HAS LOWER HYPOXIA, APOPTOSIS, AND NECROSIS, AND HIGHER PROLIFERATION THAN TUMOR SLICES CULTURED UNDER SIMILAR CONDITIONS Dina Dorrigiv1,3, Kayla Simeone1,2, Benjamin Péant1,2, Euridice Carmona1, Jennifer K. Dupont1, Anne-Marie Mes-Masson1,2, and Thomas Gervais1,3 1Centre Hospitalier de l'Université de Montréal, CANADA, 2Université de Montréal, CANADA, and 3Polytechnique Montréal, CANADA

Th7-762.f MICROFLUIDIC MODELS FOR NATURAL KILLER/CANCER CELL INTERACTIONS IN METASTASIS Heather E. Bomberger, Behiye Kodal, Martin Felices, and David K. Wood University of Minnesota, USA

Th8-862.f PARALLELIZED MICROFLUIDIC THIN CELL TRAPPERS FOR EFFECTIVELY SELECTING BLOOD CIRCULATING TUMOR CELLS Natsumi Shimmyo, Makoto Furuhata, Masumi Yamada, Rie Utoh, and Minoru Seki Chiba University, JAPAN

f - Diagnostics, Drug Testing & Personalized Medicine Neurobiology/Neuroscience W6-664.f SPATIALLY RESOLVED MICROFLUIDICS FOR STIMULATING LOCAL ISCHEMIA IN BRAIN TISSUE Michael T. Cryan, Yuxin Li, and Ashley E. Ross University of Cincinnati, USA

Th7-763.f WIRELESS BIORESORBABLE NERVE STIMULATORS WITH SOFT CUFF ELECTRODE Kyung Su Kim, Seunghun Han, and Jahyun Koo Korea University, KOREA

f - Diagnostics, Drug Testing & Personalized Medicine Clinical Chemistry M1-164.f POINT-OF-CARE DETECTION OF CIRCULATING HISTONES FOR INTERNAL TRAUMA DIAGNOSIS Micaela L. Everitt and Ian M. White University of Maryland, College Park, USA

Th8-863.f FINGER-DRIVEN PUMP ASSISTED MICROFLUIDIC PLATFORM FOR COLORIMETRIC DETECTION OF LITHIUM Angelo Traina1, Han Gardeniers2, and Burcu Gumuscu2,3 1University of Roma "La Sapienza", ITALY, 2University of Twente, THE NETHERLANDS, and 3Eindhoven University of Technology, THE NETHERLANDS

f - Diagnostics, Drug Testing & Personalized Medicine Personalized Medicine M1-165.f POINT-OF-CARE SOLUTION FOR THERAPEUTIC DRUG MONITORING ENABLED BY INTEGRATING FO-SPR READOUT INTO A SELF-POWERED MICROFLUIDIC PLATFORM Henry Ordutowski, Jiahuan Qu, Ruben Verbruggen, Francesco Dal Dosso, Saba Safdar, Nick Geukens, Debby Thomas, Dragana Spasic, and Jeroen Lammertyn KU Leuven, BELGIUM

M2-264.f A MICROFLUIDIC 3-PART DIFFERENTIAL SORTER Mohammad Aghaamoo, Ruoyu Jiang, Braulio Cardenas Benitez, and Abraham P. Lee University of California, Irvine, USA

M2-265.f WHOLE BLOOD PROFILING REVEALS BIOPHYSICAL IMMUNE RESPONSE SIGNATURES FOR CLINICAL TRIAGE Kerwin Kwek Zeming1, Rohan Vernekar2, Mui Teng Chua3,4, Kai Yun Quek1, Greg Suton2, Timm Krueger2, Win Sen Kuan3,4, and Jongyoon Han1,5 1Singapore-MIT Alliance for Research and Technology (SMART) Centre, SINGAPORE, 2University of Edinburgh, UK, 3National University of Singapore, SINGAPORE, 4National University Health System, SINGAPORE, and 5Massachusetts Institute of Technology, USA

T3-365.f A SENSOR SURFACE ENGINEERING METHODOLOGY FOR NONINVASIVE WEARABLE ELECTROACTIVE DRUG MONITORING Shuyu Lin, Wenzhuo Yu, Bo Wang, Yichao Zhao, Ke En, Jialun Zhu, and Sam Emaminejad University of California, Los Angeles, USA

T4-465.f A WEARABLE MICROFLUIDIC SYSTEM FOR HIGH SIGNAL-TO-NOISE RATIO SWEAT RATE SENSING VIA PROGRAMMABLE MICROBUBBLE GENERATION AND TRACKING Haisong Lin, Shuyu Lin, Jorge Emiliano De Dios Suarez, Harish Athavan, Yibo Wang, Wenzhuo Yu, and Sam Emaminejad University of California, Los Angeles, USA

W5-564.f AN EX VIVO TUMOR-DERIVED MODEL TO STUDY THE EFFECT OF THERAPEUTIC AGENTS USED FOR THE TREATEMENT OF CANCER PATIENTS Kayla Simeone1, Benjamin Péant1, Euridice Carmona1, Diane Provencher1, Fred Saad1, Thomas Gervais1,2, and Anne-Marie Mes-Masson1 1Université de Montréal, CANADA and 2Polytechnique de Montréal, CANADA

W6-665.f INDEX MATCHED MICROFLUIDIC DEVICES FOR PRECISE MEASUREMENT OF SINGLE CELL MASS Edward R. Polanco, Justin Griffin, and Thomas A. Zangle University of Utah, USA

Th7-764.f MECHANICAL PROPERTIES OF HYDROGEL MICRONEEDLES FOR INTERSTITIAL FLUID SAMPLING Emilee Madsen and Jacqueline C. Linnes Purdue University, USA

Th8-864.f MICROPHYSIOLOGICAL DRUG-SCREENING PLATFORM FOR PERSONALIZED LEUKEMIA TREATMENT Furkan Gökçe1, Mario M. Modena1, Beat C. Bornhauser2, and Andreas Hierlemann1 1ETH Zürich, Basel, SWITZERLAND and 2University Children's Hospital Zürich, SWITZERLAND

f - Diagnostics, Drug Testing & Personalized Medicine Pathogen Detection & Antibiotics M1-166.f MINIATURIZED DEVICE FOR PERFORMING PCR, INTEGRATED WITH AN ELECTROCHEMICAL DNA BIOSENSOR FOR DETECTION OF CORYNEBACTERIUM DIPHTHERIAE Kasper Marchlewicz1,2,3, Iga Ostrowska1, Zuzanna Iwón1, Robert Ziólkowski1, Kamil Żukowski3, Elžbieta Jastrzębska1, Zbigniew Brzózka1, and Elżbieta Malinowska1,3 1Warsaw University of Technology, POLAND, 2University of Warsaw, POLAND, and 3Centre of Advanced Materials and Technologies CEZAMAT, POLAND

M1-167.f VIRUS IDENTIFICATION BY EASY TO FABRICATE NANOPORE-CHIP USING ULTRATHIN GLASS-FILM AND OPRICAL BONDING Takatoki Yamamoto Tokyo Institute of Technology, JAPAN

M2-266.f PORTABLE MICROSCALE PLATFORM FOR MALARIA AND ANTIMALARIAL RESISTANCE SCREENING IN RESOURCE-LIMITED SETTINGS Shreya Deshmukh1, Oswald Byaruhanga2, Patrick Tumwebaze2, Bryan Greenhouse3, Elizabeth Egan1, and Utkan Demirci1 1Stanford University, USA, 2Infectious Diseases Research Collaboration, UGANDA, and 3University of California, San Francisco, USA

T3-366.f A MULTIPLEX GENETIC DIAGNOSTIC DEVICE INTEGRATED WITH VERTICAL PHASEGUIDES CAPABLE OF AUTONOMOUS DISPENSING FOR THE DETECTION OF ARBOVIRUS INFECTIONS Daigo Natsuhara1, Kisuke Tanaka1, Hiroka Aonuma2, Tatsuya Sakurai2, Moeto Nagai1, Hirotaka Kanuka2, and Takayuki Shibata1 1Toyohashi University of Technology, JAPAN and 2Jikei University School of Medicine, JAPAN

T3-367.f QUANTIFYING BACTERIAL SPORE GERMINATION BY IMPEDANCE CYTOMETRY FOR ASSESSING HOST MICROBIOTA SUCEPTIBILITY John Moore, Armita Salahi, Carlos Honrado, Christopher Warburton, Cirle Warren, and Nathan S. Swami University of Virginia, USA

T4-466.f NANO/MICROFLUIDIC DEVICE FOR EFFICIENT BACTERIA CAPTURE Tamer Abdelfattah1, Mahsa Jalali1, Roozbeh Siavash Moakhar1, Sahar Sadat Mahshid2, and Sara Mahshid1 1McGill University, CANADA and 2University of Toronto, CANADA

T4-467.f RAPID AMPLIFICATION OF FEMTOGRAMS OF DNA WITH HIGH PURITY IN DIGITAL MICROFLUIDICS FOR SEQUENCING Yuguang Liu, Patricio Jeraldo, Helena Mendes-Soares, Thao Masters, Heidi Nelson, Robin Patel, Nicholas Chia, and Marina Walther-Antonio Mayo Clinic, USA

W5-565.f AN AUTOMATED MICROFLUDICIC DIAGNOSTICS PIPELINE FOR INFECTIOUS DISEASE DETECTION IN LOW RESOURCE SETTINGS Miren Urrutia Iturritza1, Giulia Gaudenzi1,2, Ahamad Saleem Akhtar1, Inês Fernandes Pinto1, Noa Lapins1, Aman Russom1, and Håkan Jönsson1 1KTH Royal Institute of Technology, SWEDEN and 2Karolinska Institute, SWEDEN

W5-566.f RAPID BACTERIA ENRICHMENT AND DIAGNOSIS OF ANTIBIOTIC RESISTANCE FROM URINE SAMPLE Yuetao Li1, Andrew Glidle1, Julien Reboud1, Jing Zhang1, Yuanshuai Zhu1, Jonathan M. Cooper1, Wei Huang2, and Huabing Yin1 1University of Glasgow, UK and 2University of Oxford, UK

W6-666.f CELL-FREE, CRISPR/CAS-BASED PAPER DIAGNOSTICS FOR FOOD AND WATERBORNE PATHOGEN DETECTION Helena de Puig Guixe1, Michael S. Wiederoder2, Shannon K. McGraw2, and James J. Collins1 1Wyss Institute for Biologically Inspired Engineering, USA and 2US Army CCDC - Soldier Center, USA

W6-667.f RESPIDISK: A POINT-OF-CARE PLATFORM FOR FULLY AUTOMATED DETECTION OF RESPIRATORY TRACT INFECTION PATHOGENS IN CLINICAL SAMPLES Markus Rombach1, Sebastian Hin1, Mara Specht1, Benita Johannsen1, Jan Lüddecke1, Nils Paust1, Roland Zengerle1, and Konstantinos Mitsakakis2 1Hahn-Schickard, GERMANY and 2University of Freiburg, GERMANY

Th7-765.f DIRECT ISOLATION AND DETECTION OF PATHOGENIC BACTERIA USING A NANOGAP DEVICE Jung Y. Han, Michael Yeh, and Don L. DeVoe University of Maryland, College Park, USA

Th7-766.f RNA/DNA AMPLIFICATION METHODS FOR THE DETECTION OF BACTERIA AND VIRUS THROUGH AN OPTOELECTRONIC LAB-ON-CHIP Francesca Costantini1, Nicola Lovecchio2, Lorenzo Iannascoli2, Valeria Scala1, Francesco Faggioli1, Nicoletta Pucci1, Stefania Loreti1, Giampiero deCesare2, Augusto Nascetti2, and Domenico Caputo2 1CREA-DC Research Centre for Plant Protection and Certification, ITALY and 2Sapienza University of Rome, ITALY

Th8-865.f HIGH EFFICIENT AND SELECTABLE CONCENTRATION OF BACTEREMIA AND RAPID BACTERIAL ANTIBIOTIC SUSCEPTIBILITY TEST THROUGH ELECTROKINETIC CONCENTRATION MICRODEVICE Kuan-Hung Chen1, Shih-Han Lee1, Chun-Wei Lee1, Tseren-Onolt Ishdorj2, and Fan-Gang Tseng1,3 1National Tsing Hua University, TAIWAN, 2Mongolian University of Science and Technology, MONGOLIA, and 3Academia Sinica, TAIWAN

Th8-866.f SURFACE-ENHANCED RAMAN SPECTROSCOPY BASED DETECTION OF β-LACTAMASE ACTIVITY IN SMALL SAMPLES OF RESISTANT E. COLI Shannon H. Hilton, Martha David, Connor Hall, and Ian M. White University of Maryland, College Park, USA

f - Diagnostics, Drug Testing & Personalized Medicine Testing for COVID-19, Rapid Virus Testing, Pandemic Management M1-168.f LAMP BASED DETECTION OF SARS-COV-2 WITH LOW-COST OFF-THE-SHELF COMPONENTS Kamalalayam Rajan Sreejith, Muhammad Umer, Narshone Soda, Surasak Kasetsirikul, Muhammad J.A. Shiddiky, and Nam-Trung Nguyen Griffith University, AUSTRALIA

M2-267.f 3D-PRINTED CAPILLARIC CHIP FOR INSTRUMENTATION-FREE, RAPID, AND QUANTITATIVE COVID-19 SEROLOGICAL TESTING USING SALIVA Oriol Ymbern, Ahmad Sohrabi, Azim Parandakh, Vahid Karamzadeh, Johan Renault, Marziye Mirbagheri, Zijie Jin, Justin Lessard-Wajcer, Jay Pimprikar, Molly Shen, Lorenna Oliveira, Yiannis Paschalidis, Andy Ng, and David Juncker McGill University, CANADA

M2-268.f LATERAL FLOW ASSAY FOR THE DETECTION OF NOROVIRUS USING PEPTIDE-COATED GOLD NANOPARTICLES Taeyeong You, Woojin Jeong, Sun Min Kim, and Tae-Joon Jeon Inha University, KOREA

T3-368.f A MICROFLUIDIC APPROACH TO RAPID CRISPR-BASED DETECTION OF SARS-COV-2 RNA Ashwin Ramachandran, Diego A. Huyke, Eesha Sharma, Malaya K. Sahoo, Niaz Banaei, Benjamin A. Pinsky, and Juan G. Santiago Stanford University, USA

T3-369.f MICRO-RAPID AUTONOMOUS ANALYTICAL DEVICE FOR SARS-COV-2 DETECTION Jacqueline C. Linnes, Navaporn (Amy) Sritong, Ashlee Colbert, and Karin F.K. Ejendal Purdue University, USA

T4-468.f AN ADAPTABLE, MASS PRODUCTION CAPABLE, MICROFLUIDIC MIXER FOR POINT OF CARE SAMPLE PREP Priscilla Delgado, Pranav Dorbala, Abhijit Ravindran, and David Myers Emory University, USA

W5-567.f DETECTION OF AVIAN INFLUENZA VIRUS AND ITS ANTIBODY BY FLUORESCENCE POLARIZATION IMMUNOASSAY Keine Nishiyama1, Yohei Takeda2, Masatoshi Maeki1, Akihiko Ishida1, Hirofumi Tani1, Koji Shigemura3, Akihide Hibara4, Haruko Ogawa2, and Manabu Tokeshi1 1Hokkaido University, JAPAN, 2Obihiro University of Agriculture and Veterinary Medicine, JAPAN, 3Tianma Japan, Ltd., JAPAN, and 4Tohoku University, JAPAN

W6-668.f ELECTROCHEMICAL CAPILLARY-FLOW IMMUNOASSAY FOR THE DETECTION OF ANTI- SARS-COV-2 ANTIBODIES Isabelle C. Samper1, Ana Sánchez-Cano1,2, Wisarut Khamcharoen1,3, Ilhoon Jang1, Brian J. Geiss1, David S. Dandy1, and Charles S. Henry1 1Colorado State University, USA, 2Universitat Autònoma de Barcelona, SPAIN, and 3Srinakharinwirot University, THAILAND

Th7-767.f HANDHELD LIGHTWEIGHT BATTERY-OPERATED REAL-TIME PCR DEVICE FOR COVID-19 DIAGNOSIS Geoffrey Mulberry, Matthew Moench, and Brian N. Kim University of Central Florida, USA

Th8-867.f HIGHLY PERFORMING POINT-OF-CARE MOLECULAR TESTING FOR SARS-COV-2 WITH RNA EXTRACTION AND ISOTHERMAL AMPLIFICATION. Etienne Coz1, Pierre Garneret1, Elian Martin1, Jean-Claude Manuguerra2, Elodie Brient-Litzler2, Vincent Enouf2, Daniel Felipe Gonzalez Obando2, Jean Christophe Olivo-Marin2, Fabrice Monti1, Sylvie Van der Werf2, and Patrick Tabeling2 1ESPCI, FRANCE and 2Institut Pasteur, FRANCE

f - Diagnostics, Drug Testing & Personalized Medicine Drug Screening and Development M1-169.f MICROFLUIDIC GRADIENT GENERATOR FOR DRUG SCREENING APPLICATIONS Arian Jaberi1, Amir Monemian Esfahani1, Ali Tamayol1,2, and Ruiguo Yang1 1University of Nebraska, Lincoln, USA and 2University of Connecticut, USA

M2-269.f MICROFLUIDIC IMMOBILIZED ENZYME REACTOR FOR DETERMINING THE ELIMINATION OF ENVIRONMENTAL DRUG RESIDUES IN FISH Vera Kouhi, Tea Pihlaja, Elisa Ollikainen, and Tiina Sikanen University of Helsinki, FINLAND

T4-469.f ''CUBOIDS'' FOR MULTIPLEXED MICROFLUIDIC DRUG TESTING OF INTACT TISSUES Adán Rodríguez, Lisa Horowitz, and Albert Folch University of Washington, USA

W5-568.f ARTIFICIAL BRAIN ''CELLS-ON-A-CHIP'' FOR DRUG PERMEABILITY PREDICTION Jaime L. Korner and Katherine S. Elvira University of Victoria, CANADA

W6-669.f DROPLET-BASED APPROACH TO HIGH SPEED DRUG DISCOVERY Stacey Markovic1, Ryan A. Dubay1,2, Peter Hsi1, Nerses J. Haroutunian1, Cassie M. Bryan1, Kettner Griswold Jr.1, Eric M. Darling2, Andrew P. Magyar1, and Vishal Tandon1 1Draper Laboratory, USA and 2Brown University, USA

Th7-768.f ESTABLISHMENT OF AN AUTOMATIZED MICROFLUIDIC PLATFORM FOR SCREENING OF NOVEL HBV CAPSID ASSEMBLY MODULATORS (CAMS) Tamás Vermes1,2, Thomas Henkel3, Helmut Buschmann1, Miquel A. Pericàs2, Esther Alza2, Thomas Goldner1, and Andreas Urban1 1AiCuris Anti-infective Cures GmbH, GERMANY, 2Institute of Chemical Research of Catalonia (ICIQ), SPAIN, and 3Leibniz Institute of Photonic Technology (IPHT), GERMANY

Th8-868.f HIGH-THROUGHPUT GENERATION OF UNIFORM CEREBRAL BRAIN ORGANOIDS Kyungwon Park1, Yong Hun Jung1, and Seok Chung1,2 1Korea University, KOREA and 2Korea Institute of Science and Technology (KIST), KOREA

f - Diagnostics, Drug Testing & Personalized Medicine Drug Delivery T3-370.f 2D AND 3D TUMOR MODELS ON-A-CHIP TO EVALUATE EFFECTIVENESS OF PHOTODYNMIC THERAPY (PDT) WITH GRAPHENE OXIDE CONJUGATES Agnieszka Zuchowska, Bartlomiej Dabrowski, Artur Kasprzak, Ksenia Kaminska, Magdalena Poplawska, and Zbigniew Brzozka Warsaw University of Technology, POLAND

T4-470.f A NOVEL MICROSYSTEM FOR STUDYING THE EFFECTIVENESS OF ELECTROCHEMOTHERAPY AND CHEMOTHERAPY PROCEDURES Sandra Skorupska, Ilona Grabowska-Jadach, Malgorzata Pieta, Artur Dybko, and Zbigniew Brzozka Warsaw University of Technology, POLAND

W5-569.f DRUG LOADING INTO EXTRACELLULAR VESICLE VIA TONICITY CONTROL Chaeeun Lee1,2, Sumit Kumar2, Juhee Park2, Junyoung Kim1,2, and Yoon-Kyoung Cho1,2 1Ulsan National Institute of Science and Technology (UNIST), KOREA and 2Institute for Basic Science (IBS), KOREA

W6-670.f HIGH-THROUGHPUT MICROFLUIDICS FOR EVALUATING MICROBUBBLE ENHANCED DELIVERY OF CANCER THERAPEUTICS IN SPHEROID CULTURES Matthew D. Bourn1,2, Damien V.B. Batchelor1, Nicola Ingram2, James McLaughlan1,2, P. Louise Coletta2, Stephen D. Evans1, and Sally A. Peyman1,2 1University of Leeds, UK and 2St James' University Hospital, UK

Th7-769.f MASSIVELY PARALLEL INTRACELLULAR DELIVERY USING TITANIUM OXIDE NANOTUBES Loganathan Mohan1, Srabani Kar2, Ren Hattori1, Miho Ishii-Teshima1, Kavitha Illath2, Anuj Tiwari1, Tuhin Subhra Santra3, Takayuki Shibata1, and Moeto Nagai1 1Toyohashi University of Technology, JAPAN, 2University of Cambridge, UK, and 3Indian Institute of Technology Madras, INDIA

f - Diagnostics, Drug Testing & Personalized Medicine Others M1-170.f INSTANT LABELING OF THERAPEUTIC STEM CELLS WITH MICROFLUIDICS FOR IN VIVO TRACKING Todd Sulchek1, Hossein Nejadnik2, Kyung Oh Jung2, Ashok J. Theruvath2, Anna Liu2, Wei Wu2, Louise Kiru2, Guillem Pratx2, and Heike E. Daldrup-Link2 1Georgia Institute of Technology, USA and 2Stanford University, USA

M2-270.f USING RBC SHAPES TO DISTINGUISH BETWEEN SICKLE CELL DISEASE AND TRAIT SAMPLES Riddha Manna, Oshin Sharma, Anish Mahto, Srushti Singh, and Debjani Paul Indian Institute of Technology, Bombay, INDIA

T3-371.f PORTABLE AND AUTOMATED ANALYZER FOR RAPID AND HIGH PRECISION IN VITRO DISSOLUTION OF DRUGS Zhongmei Chi1, Yunxiang Feng2, and Li Yang1 1Northeast Normal University, CHINA and 2Jingke-Oude Science and Education Instruments Co., Ltd., CHINA

Th8-869.f DEVELOPMENT OF A METHOD FOR CELL DELIVERY INTO THE SUBRETINAL SPACE USING BIODEGRADABLE NANOSHEETS Kazuya Yamashita, Hideto Kojima, Nobuhiro Nagai, Toshiaki Abe, and Hirokazu Kaji Tohoku University, JAPAN

f - Diagnostics, Drug Testing & Personalized Medicine Industrial Benefactor Th7-782.f MICROFLUIDIC METHODS OF AUTOMATED LIPOSOME LIBRARY GENERATION Valentina Nappo, Gurinder Vinner, Ben Knappett, Damiano Rossi, Richard H. Gray Dolomite Microfluidics, UK

f - Diagnostics, Drug Testing & Personalized Medicine Late News M1-181.f AN EASY-TO-USE MICROFLUIDIC CHIP WITH ISOTHERMAL NUCLEIC ACID AMPLIFICATION FOR RAPID COVID-19 DETECTION Dan Liu1, Haicong Shen2, Yuqian Zhang1, and Chaoyong Yang2 1Huaqiao University, CHINA and 2Xiamen University, CHINA

M2-280.f 3D NANO-PATTERNED FLUIDIC INTERFACE ENABLES ULTRASENSITIVE DETECTION OF CIRCULATING EXOSOMES FOR IMMUNOTHERAPY RESPONSE PREDICTION Lingling Wu1, Jiafeng Gao1, and Chaoyong Yang1,2 1Shanghai Jiao Tong University, CHINA and 2Xiamen University, CHINA

M2-281.f ELECTROCHEMICAL IMPEDANCE-BASED DETECTOR FOR SARS-COV-2 ANTIBODIES Mohamed Z. Rashed1, Jonathan A. Kopechek1, Mariah C. Priddy1, Krystal T. Hamorsky1, Kenneth E. Palmer1, Nikhil Mittal2, Joseph Valdez2, and Stuart J. Williams1 1University of Louisville, USA and 2Agilent Technologies Inc, USA

T3-381.f AT-HOME BLOOD COLLECTION AND RNA STABILIZATION USING A CAPILLARY PRESSURE BASED DEVICE Amanda J. Haack, Fang Yun Lim, Dakota S. Kennedy, Jing J. Lee, Erwin Berthier, and Ashleigh B. Theberge University of Washington, USA

T3-382.f IFAST AND RT-LAMP: AN APPROACH FOR ON-CHIP DETECTION OF SARS-CoV-2 RNA FOR RESOURCE-LIMITED SETTINGS Pablo Rodriguez-Mateos1, Bongkot Ngamsom1, Cheryl Walter1, Charlotte E. Dyer1, Jesse Gitaka2, Alexander Iles1, and Nicole Pamme1 1University of Hull, UK and 2Mount Kenya University, KENYA

T4-481.f HIERARCHICAL MULTIVALENT APTAMERS-PRINTED MICROFLUIDIC DEVICE FOR ISOLATING CIRCULATING FETAL CELLS Huimin Zhang1, Xiyuan Yu1, Yilong Liu2, Bingqian Lin2, Yidi Wang2, Yanling Song2, Zhi Zhu2, and Chaoyong Yang1,2 1Shanghai Jiao Tong University School of Medicine, CHINA and 2Xiamen University, CHINA

T4-482.f HIGH THROUGHPUT GLOMERULUS EXPERIMENTAL MODEL DEVICE WITH MECHANICAL FILTRATION FOR DRUG DISCOVERY RESEARCH Kotaro Doi1, Hiroshi Kimura2, Masaomi Nangaku1, and Teruo Fujii1 1University of Tokyo, JAPAN and 2Tokai University, JAPAN

W5-580.f AN ULTRASENSITIVE DETECTION OF AGGREGATED α-SYNUCLEIN AS A BIOMARKER MOLECULE FOR PARKINSON DISEASE BY LIPOSOME-IMMOBILIZED CANTILEVER BIOSENSOR USING SELF-TEMPLATING PHENOMENA OF PRIONOID PROTEIN Ryoko Kobayashi1, Masanori Sawamura2, Hodaka Yamakado2, Masayuki Sohgawa3, and Minoru Noda1 1Kyoto Institute of Technoligy, JAPAN, 2Kyoto University, JAPAN, and 3Niigata University, JAPAN

W5-581.f MICRO-IMPLANTS WIRELESS DEVICE FOR DEEP TISSUE PHOTO THERAPEUTICS Sophie Wan Mei Lian1, Jin Yunxia2, John S. Ho1,2, and Chia-Hung Chen3 1National University of Singapore, SINGAPORE, 2Institute for Health Innovation and Technology (iHealthtech) and 3City University of Hong Kong, HONG KONG

W6-681.f ELECTROMECHANICAL LAB-ON-A-CHIP PLATFORM FOR CREATININE ANALYSIS USING AUTOMATED ELISA PROTOCOLS Betul Karakuzu, E. Alperay Tarim, Cemre Oksuz, and H. Cumhur Tekin Izmir Institute of Technology, TURKEY

W6-682.f HUMAN NEUTROPHIL CHEMOTAX THROUGH TAPERED CHANNELS IN RESPONSE TO COMPLEMENT ACTIVATION AND INHIBITION Sinan Muldur and Daniel Irimia Massachusetts General Hospital, Harvard Medical, Shriners Hospital for Children, USA

Th7-780.f PERSONALIZED ANTIBIOTHERAPY VIA ''FINGER PRICK'' BLOOD TEST H. Ceren Ates, Nils Schneider, Hasti Mohsenin, Wilfried Weber, Gerald Urban, and Can Dincer University of Freiburg, GERMANY

Th8-878.f MICROFLUIDIC ASSAYS MEASURING NEUTROPHIL RESPONSES TO BORRELIA BURGDORFERI IDENTIFY COMPLEMENT COMPONENT C5A AS A KEY MEDIATOR Felix Ellett, Sinan Mulder, Anika L. Marand, Charles Marvil, John Branda, Jacob E. LeMieux, Adam B. Raff, Klemen Strle, and Daniel Irimia Massachusetts General Hospital, Harvard Medical, Shriners Hospital for Children, USA

g - Other Applications of Microfluidics Artificial Intelligence and Microfluidics T4-471.g AI-ASSISTED MICROFLUIDIC STIFFNESS GRADIENT FOR ANALYSIS OF 3D CELL CULTURES IN HYDROGEL BEADS Vasileios Anagnostidis, Dalia Al-Saadi, and Fabrice Gielen University of Exeter, UK

W5-570.g AI-GUIDED MICROFLUIDIC SYNTHESIS OF COLLOIDAL LEAD HALIDE PEROVSKITE QUANTUM DOTS Robert W. Epps1, Amanda A. Volk1, Kameel Abdel-Latif1, Kristofer G. Reyes2, and Milad Abolhasani1 1North Carolina State University, USA and 2University of Buffalo, USA

W6-671.g DEEP LEARNING CLASSIFICATION OF PARTICLE DEPTH FOR DEFOCUSING 3D-3C micro-PTV Evan Lammertse1, Martin Sauzade1, Hongxiao Li2, Jun Kong2, and Eric Brouzes1 1Stony Brook University, USA and 2Georgia State University, USA

Th7-770.g FLOW FOCUS-FREE IMAGE FLOW CYTOMETRY BY IMAGE PROCESSING AND DATA ESTIMATION Arpith Vedhanayagam and Amar S. Basu Wayne State University, USA

Th8-870.g INTELLIGENT ON-CHIP ANALYSIS OF THROMBOSIS IN ECMO WITH A GOAT MODEL Yuqi Zhou1, Atsushi Yasumoto1,2, Masako Nishikawa1, Yuya Nobori1, Yi Wang1, Masaki Anraku1,3, Yutaka Yatomi1, and Keisuke Goda1,4,5 1University of Tokyo, JAPAN, 2Hokkaido University Hospital, JAPAN, 3Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, JAPAN, 4Wuhan University, CHINA, and 5University of California, Los Angeles, USA

g - Other Applications of Microfluidics Fuel Cells & Energy M1-171.g COTTON-BASED MICROFLUIDIC EVAPORATOR TO ENHANCE THE PERFORMANCE OF A THERMOELECTRIC DEVICE Liang Jun Zheng, Dong Hee Kang, Na Kyong Kim, and Hyun Wook Kang Chonnam National University, KOREA

M2-271.g FLUORESCENT VISUALIZATION OF OIL DISPLACEMENT IN A MICROFLUIDIC DEVICE FOR ENHANCED OIL RECOVERY APPLICATIONS Khashayar R. Bajgiran, Hannah C. Hymel, Shayan Sombolestani, Nora Safa, Nathalie Dante, James A. Dorman, Dandina Rao, and Adam T. Melvin Louisiana State University, USA

T3-372.g UNDERSTANDING POLYMER RETENTION IN POROUS FORMATIONS USING MICROFLUIDICS Antonia Sugar, Maged F. Serag, Ulrich Buttner, Satoshi Habuchi, and Hussein Hoteit King Abdullah University of Science & Technology (KAUST), SAUDI ARABIA

g - Other Applications of Microfluidics Microfluidics for X-Ray and e-Beam Applications T4-472.g THREE DIMENSIONAL HYDRODYNAMIC FOCUSING IN A MONOLITHIC FUSED SILICA MICROFLUIDIC DEVICE Diego A. Huyke1, Ashwin Ramachandran1, Thomas Kroll2, Daniel P. DePonte2, and Juan G. Santiago1 1Stanford University, USA and 2SLAC National Accelerator Lab, USA

g - Other Applications of Microfluidics Others W5-571.g AEROSOLIZED DROPLETS AND OPEN MICROFLUIDICS FOR CAPTURING AT-HOME AIRBORNE EXPOSURES Ulri N. Lee, Tammi L. van Neel, Fang Yun Lim, Jean Berthier, Erwin Berthier, and Ashleigh B. Theberge University of Washington, USA

W6-672.g REPROGRAMMABLE FERROMAGNETIC DOMAINS FOR RECONFIGURABLE SOFT MAGNETIC ACTUATORS Hyeonseo Song, Hajun Lee, Jaebyeong Lee, Jun Kyu Choe, Suwoo Lee, Jee Yoon Yi, Sunghoon Park, Jung-Woo Yoo, Min Sang Kwon, and Jiyun Kim 1Ulsan National Institute of Science & Technology (UNIST), KOREA and 2Seoul National University, KOREA

Th7-771.g TOWARDS ASTROBIOLOGICAL NANOSATELLITE MISSION – LOC INSTRUMENTATION FOR CELL CULTIVATION RESEARCH IN SPACE Agnieszka Podwin1, Patrycja Śniadek1, Adrianna Graja1,2, Bartosz Kawa1, Marcin Bialas1, Wojciech Kubicki1, Marta Jurga3, Agata Kaczmarek3, Krzysztof Matkowski3, Rafal Walczak1, and Jan Dziuban1 1Wroclaw University of Science and Technology, POLAND, 2SatRevolution S.A., POLAND, and 3Wroclaw University of Environmental and Life Sciences, POLAND

g - Industrial Benefactor W5-572.g A COMPARISON OF CYCLO OLEFIN POLYMER WITH GLASS AND OTHER PLASTICS FOR THE CONSTRUCTION OF MOLECULAR DIAGNOSTIC CONSUMABLE DEVICES Tachi Sawaguchi, Shotaro Suzuki, Hiro Fujiki, Toshiro Katayama, and Larry Atupem Zeon Specialty Materials Inc., USA

g - Other Applications of Microfluidics Late News Th7-781.g A KINETIC MATCHING APPROACH ON MICROFLUIDIC PAPER-BASED ANALYTICAL DEVICES FOR RAPID ASSESSMENT OF TOTAL POLYPHENOL CONTENT IN TEA Qinqin Zheng1,3, Zhenxia Hao1,2, Lili Jin1, Hongping Chen1,2, and Chengyin Lu1,2 1Chinese Academy of Agricultural Sciences, CHINA, 2Ministry of Agriculture and Rural Affairs, CHINA, and 3Graduate School of Chinese Academy of Agricultural Sciences, CHINA