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NEWS OF THE TEXAS MEDICAL CENTER — VOL. 5 / NO. 9 — OCTOBER 2018 NEWS OFOF THETHE TEXASTEXAS MEDICALMEDICAL CENTER CENTER — — VOL. VOL. 5 5/ NO./ NO. 8 9— —SEPTEMBER OCTOBER 20182018 Keeping His Heart in the Game Surgery with minimal cuts offers quick recovery, p. 20 STDs HIT A TOOLKIT FOR BREAST RECORD HIGH, NEWBORNS RECONSTRUCTION p. 12 IN NEED, REVOLUTION, p. 14 p. 29 CENTERED LIVING LUXURY APARTMENT HOMES In The Houston Medical Center MICRO UNITS TO PENTHOUSES 10 Weeks Free Rent* Book Your Tour Today 713-527-1000 EQUAL HOUSING OPPORTUNITY *Restrictions May Apply. Ask for Details. LatitudeMedCenter.com *Restrictions May Apply. Ask for Details. President’s Perspective TMC | PULSE Vol. 5 No. 9 October 2018 President and Chief Executive Officer William F. McKeon Communications Director Ryan Holeywell Pulse Editor Maggie Galehouse [email protected] Assistant Editor Cindy George [email protected] Staff Writers Alexandra Becker Mark Mulligan/© Houston Chronicle. Used with permission. with Used Chronicle. Houston Mark Mulligan/© Christine Hall WILLIAM F. McKEON Britni R. McAshan President and Chief Executive Officer Shanley Pierce Texas Medical Center Photojournalist Cody Duty recently traveled to London and, together with of Leeds, with the leadership of the Texas Medical United Kingdom government and research leader- Center. Researchers from both countries will collab- Contributing Photographer I ship, announced a BioBridge partnership between orate on a range of projects, including the devel- Scott Dalton the Texas Medical Center and the UK. This unique opment and advancement of genomics and cancer NEWSROOM collaboration is a testament to the Texas Medical treatments. For example, researchers are developing 713-791-8812 Center (TMC) and the UK’s commitment to fostering ways to use artificial intelligence to target treatments [email protected] the cross-pollination of ideas and innovation in the based on an individual’s distinctive genomic profile. life sciences to accelerate discovery. It was exciting to see the genuine support and ADVERTISING What, exactly, does this part- enthusiasm from UK partners, Felicia Zbranek-Zeitman nership mean? First, it solves a including Baroness Rona Fairhead, 713-791-8829 key challenge facing early stage UK Minister of State for the [email protected] companies. Those startups require Department of International Trade; DISTRIBUTION a great deal of nurturing and and Sir Mark Walport, chief exec- Daniel Martinez support, and that’s especially true utive of UK Research Innovation, 713-791-6136 when they expand beyond their a government funding agency; [email protected] home country into new markets. along with leaders of some of the READ US ONLINE most prestigious universities in The BioBridge aligns the life sci- tmc.edu/news ence startup communities across the United Kingdom and the Texas the UK with the TMC Innovation McKeon, Fairhead and Walport Medical Center. FOLLOW US Institute. UK-based companies are Importantly, we don’t see @TXMedCenter now able to house themselves at the TMC and tap this as a one-time partnership. We’ve established a @texasmedcenter @thetexasmedicalcenter into our network of investors and experts. And the BioBridge with Australia, as well, and we expect to reverse is true, too: startups housed here at the develop more of these types of relationships as we TMC Pulse is an award-winning continue to advance the Texas Medical Center’s role TMC now will have an access point into the UK. monthly publication of the Texas The BioBridge serves as a mutual port of entry, as an international leader—and partner—in the Medical Center in Houston, Texas. where startups can establish a base and learn the life sciences. Permission from the editor is regulatory nuances of a new market while building Our BioBridge partnership is designed to share required to reprint any material. key relationships. knowledge, technologies and insights to leverage our Second, the BioBridge aligns leading UK insti- collective capabilities to develop treatments faster. tutions, including Cambridge University, Oxford We are united in our passion and dedication for University, Manchester University and the University improving the health of humanity. 2 t m c » p u l s e | o c to b e r 2018 Table of Contents OCTOBER 2018 6 On the Side: Christina Wells 8 Spotlight: William Zoghbi, M.D. 33 Curated: Smiles are Contagious 38 Field Notes 40 Calendar on this page: Rebecca Richards-Kortum, Ph.D., professor of bioengineering and director of the Rice 360° Institute for Global Health at Rice University, in her lab at the BioScience Research Collaborative. on the cover: Ethan Page performs a drill during baseball practice. 4 26 34 36 Analysis: Health Care Vampire Facial: Solutions: Connecting the Digital Pathology Shouldn’t Cause Not that Bloody Warburg Pathway to Improving Diagnoses Financial Pain Cancer Growth Analysis: Health Care Shouldn’t Cause Financial Pain Studies show Americans are feeling the squeeze By Ryan Holeywell gruesome scene played out earlier this year For many, the status quo means that a growing Ain Boston that illustrates the state of health WHAT HAPPENS percentage of family income will continue to go care for many of today’s consumers. As a pas- WHEN YOU RECEIVE A toward health care costs at the expense of saving senger exited a rush-hour transit train, her foot COSTLY MEDICAL BILL? for retirement, college or starting a business. got caught in the gap between the train and the National Results The realities of managing medical bills can have platform. Bloodied, with a laceration deep enough a major, disruptive effect on Americans’ lives. to reveal bone, she begged nearby commuters About 60 percent of people who say they struggle n Pay in full not to call an ambulance. “It’s $3,000,” she said, with medical bills exhaust most or all of their right away according to a Boston Globe reporter on the scene. savings to pay them. The same proportion take 37.5% “I can’t afford that.” n Pay what I can, on second jobs or work more hours to pay The story went viral, garnering national when I can medical bills. attention for how perfectly it captured the terrible For American families, the prospect of losing n dilemma many Americans face when they interact Pay in agreed everything due to an unfortunate combination of upon installments 23.8% with the United States health care system. The injury and inadequate insurance is an ever- system can ease patients’ physical pain, but, in n Don’t pay until present threat. One recent study found that med- exchange, it often demands that they endure collection agency ical bills are the single largest cause of consumer extreme financial pain. 29.2% bankruptcy, responsible for between 18 and 25 New survey data from the Texas Medical n Don’t pay percent of cases. Two-thirds of Americans who 2.5% Center Health Policy Institute sheds light on how struggle with their medical bills say they’re the 6.9% that predicament affects families across the coun- result of a one-time, short-term expense, such as a try. For example, the survey shows that nearly single hospital stay or treatment for an accident, Due to rounding, total does not add up to 100%. two-thirds of Americans can’t pay the bill in full according to a Kaiser Family Foundation survey. when they receive a costly invoice for medical In other words, even if you think you’re healthy, care. Half of Americans say they must cut back I HAVE TO CUT DOWN you could be at risk. on other household expenses to pay for their The U.S. has been a center of medical inno- health care. ON OTHER EXPENSES vation, developing cutting edge drugs, proce- These were problems that should have been TO PAY FOR HEALTH CARE dures and tests to identify and fight disease. But eased by now. More than eight years after the National Results the country has failed to innovate in an equally Affordable Care Act became law, health care costs important area: developing policies to ensure that continue to challenge families. Americans of n Strongly all patients can utilize those advancements. It all types are feeling the squeeze. For those with agree should come as no surprise that most Americans 18% Marketplace (Obamacare) plans, premiums have 27% say they delay necessary medical care due to cost. doubled in just five years, and family deductibles n Somewhat Do we want our friends to take on second jobs agree average a staggering $11,500. Those who get 31% if they are unlucky enough to get sick? Do we 24% insurance through their employers face their own n Somewhat want our family members to lose their retirement challenges. Premiums are increasing faster than disagree savings if they have the bad fortune to suffer an wages and a growing number of businesses are accident? Citizens of most other Western coun- steering their employees toward high-deductible n Strongly tries have answered “of course not.” In the U.S., disagree health plans that force workers to bear a growing many observers have been asking whether rising share of health care costs. And, of course, the health care costs are sustainable. The truth is, they 10 percent of non-elderly adults without any Source: “The Nation’s Pulse: The Texas Medical Center’s Consumer Survey,” probably are—the trend has continued unabated health insurance are in the most precarious which pulled data from more than 5,000 participants nationwide for years. The real question is whether we will position of all. continue to accept them. Ryan Holeywell leads communications for the Texas Medical Center Health Policy Institute. 4 t m c » p u l s e | o c to b e r 2018 t m c » p u l s e | o c to b e r 2018 Please don’t say, I wish I’d done “something sooner.