US 20140256687A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2014/0256687 A1 Tamura et al. (43) Pub. Date: Sep. 11, 2014
(54) AGRICULTURAL AND HORTICULTURAL Publication Classi?cation INSECTICIDE COMPOSITION AND METHOD FOR USING THE SAME (51) Int. Cl. A01N57/14 (2006.01) (75) Inventors: Shingo Tamura, Tokyo (JP); Takao A01N57/12 (2006.01) Aoki, Osaka (JP); Ken Kuriyama, A01N 41/10 (2006.01) Tokyo (JP) (52) U.S. Cl. CPC ...... A01N57/14 (2013.01); A01N41/10 (73) Assignee: NIHON NOHYAKU CO., LTD., Tokyo (2013.01); A01N57/12 (2013.01) (JP) USPC ...... 514/136 (21) Appl. No.: 14/125,508 (57) ABSTRACT Provided are an agricultural and horticultural insecticide (22) PCT Filed: Jun. 28, 2012 composition comprising ?ubendiamide and dichlorvos and/ or profenofos as active ingredients; and a method for using an (86) PCT No.: PCT/JP2012/066474 agricultural and horticultural insecticide composition, com § 371 (0X1)’ prising treating insect pests directly, treating crops potentially (2), (4) Date: Feb. 14, 2014 infested With the insect pests, or treating surrounding soil or cultivation medium of the crops With an effective amount of (30) Foreign Application Priority Data an agricultural and horticultural insecticide composition comprising ?ubendiamide and dichlorvos and/ or profenofos Jun. 29, 2011 (JP) ...... 2011444379 as active ingredients. US 2014/0256687 A1 Sep. 11,2014
AGRICULTURAL AND HORTICULTURAL stances, the development of novel technologies for ef?ciently INSECTICIDE COMPOSITION AND controlling insect pests that have been dif?cult or impossible METHOD FOR USING THE SAME to control is desired.
TECHNICAL FIELD Solution to Problem [0001] The present invention relates to an agricultural and [0013] The present inventors conducted extensive research horticultural insecticide composition comprising ?ubendia to solve the above-described problems. As a result, the mide and dichlorvos and/ or profenofos as active ingredients; present inventors found that a combined use of ?ubendiamide and a method for using the same. (general name) (chemical name: 3-iodo-W-(2-mesyl-1,1 dimethylethyl) -N- {4 -[1 ,2, 2, 2-tetra?uoro -1 -(tri?uorom BACKGROUND ART ethyl)ethyl]-o-tolyl}phthalamide), known as an agricultural and horticultural insecticide, and dichlorvos (general name) [0002] Flubendiamide is a commercially available com (chemical name: 2,2-dichlorovinyl dimethyl phosphate) and/ pound as an agricultural and horticultural insecticide. It is or profenofos (general name) (chemical name: O-4-bromo known that various combinations of ?ubendiamide or its rela 2-chlorophenyl O-ethyl S-propyl phosphorothioate), simi tive compound and an agricultural and horticultural insecti larly each known as an agricultural and horticultural cide have a complementary effect on the insecticidal spec trum and that speci?c combinations of them produce a insecticide, has advantages over a separate use of each com pound, such as remarkable synergistic effect, expansion of synergistic effect (for example, see Patent Literature 1 to 5 the range of target insect pests, dose reduction, reduction of and Non Patent Literature 1). Dichlorvos and profenofos are treatment frequency, etc. Thus, the present invention was also commercially available compounds as agricultural and completed. horticultural insecticides (for example, see Patent Literature 6 and 7 and Non Patent Literature 1). However, compositions [0014] That is, the present invention relates to the follow comprising a combination of ?ubendiamide and dichlorvos ing. and/ or profenofos are not known, and it is not known at all that [1] An agricultural and horticultural insecticide composition the insecticidal effect of such a composition is synergistically comprising ?ubendiamide and dichlorvos and/ or profenofos greater than that of each compound used separately. as active ingredients. [2] The agricultural and horticultural insecticide composition CITATION LIST according to the above [1], comprising 0.1 to 10 parts by mass of dichlorvos and/or profenofos per part by mass of ?uben Patent Literature diamide. [0003] Patent Literature 1: JP-A 2001 -131 141 [3] A method for using an agricultural and horticultural insec [0004] Patent Literature 2: WO 2002/087334 ticide composition, comprising treating insect pests directly, treating crops potentially infested with the insect pests, or [0005] Patent Literature 3: WO 2004/034786 treating surrounding soil or cultivation medium of the crops [0006] Patent Literature 4: WO 2005/004603 with an effective amount of an agricultural and horticultural [0007] Patent Literature 5: WO 2005/004604 insecticide composition comprising ?ubendiamide and [0008] Patent Literature 6: US. Pat. No. 2,956,073 dichlorvos and/or profenofos as active ingredients. [0009] Patent Literature 7: GB Patent No. 1417116 [4] A method for controlling agricultural and horticultural insect pests, comprising treating insect pests directly, treating Non Patent Literature crops potentially infested with the insect pests, or treating surrounding soil or cultivation medium of the crops with an [0010] Non Patent Literature 1: effective amount of an optionally diluted formulation con [0011] The Pesticide Manual 14th Edition (British Crop taining ?ubendiamide as an active ingredient and an effective Production Council) amount of an optionally diluted formulation containing dichlorvos and/or profenofos as an active ingredient(s), the SUMMARY OF INVENTION two formulations being used separately but in the same period. Technical Problem [5] A method for controlling agricultural and horticultural [0012] In the production of agricultural produce, the dam insect pests, comprising treating insect pests directly, treating age caused by various insect pests is still large and treatment crops potentially infested with the insect pests, or treating with various insecticides is required for control of the insect surrounding soil or cultivation medium of the crops with an pests. Such insecticide treatment imposes a particularly great effective amount of an optionally diluted formulation con burden on farmers, and reducing the treatment operation has taining ?ubendiamide as an active ingredient and an effective been strongly desired in terms of occupational health, in amount of an optionally diluted formulation containing particular the reduction of farmers’ workload, as well as in dichlorvos and/or profenofos as an active ingredient(s), the terms of economics, in particular the reduction of production two formulations being used separately at a given interval. costs of agricultural produce. To this end, various kinds of [6] A method for controlling agricultural and horticultural agricultural and horticultural insecticide compositions have insect pests, comprising mixing an effective amount of a been developed. However, in conventional art, effective pest formulation containing ?ubendiamide as an active ingredient control cannot be achieved in some cases because of the kind and an effective amount of a formulation containing dichlo of insect pest to be controlled, habitat characteristics, devel rvos and/or profenofos as an active ingredient(s); optionally opment of insecticide resistance, etc. Under such circum diluting the mixture; and treating insect pests directly, treat US 2014/0256687 A1 Sep. 11,2014
ing crops potentially infested with the insect pests, or treating suspension concentrate (?owable), an emulsi?able suspen surrounding soil or cultivation medium of the crops with the sion concentrate, an emulsi?able concentrate, a soluble con optionally diluted mixture. centrate, a wettable powder, a water-dispersible granule, a granule, a dust, a microcapsule, a capsule, a tablet, a jumbo Advantageous Effects of Invention and a pack. [0015] The present invention relates to an agricultural and [0019] The inactive carrier may be a solid or liquid carrier. horticultural insecticide composition comprising ?ubendia Examples of the solid carrier include natural minerals, such as mide and dichlorvos and/ or profenofos as active ingredients; quartz, clay, kaolinite (kaolin), pyrophyllite, sericite, talc, and a method for using the same. The agricultural and horti bentonite, acid clay, attapulgite, zeolite and diatomite; inor cultural insecticide composition and the method have advan ganic salts, such as calcium carbonate, ammonium sulfate, tages over a separate use of each compound, such as remark sodium sulfate and potassium chloride; organic solid carriers, able synergistic effect, expansion of the range of target insect such as synthetic silicic acid, synthetic silicates, starch, cel pests, dose reduction, reduction of treatment frequency, etc. lulose and plant powders (for example, sawdust, coconut Therefore, the present invention provides a novel technology shell, corn cob, tobacco stalk, etc.); plastics carriers, such as for ef?ciently controlling insect pests that have been impos polyethylene, polypropylene and polyvinylidene chloride; sible or dif?cult to control by conventional technologies. urea; hollow inorganic materials; hollow plastic materials; and fumed silica (white carbon). These solid carriers may be used alone or in a combination of two or more kinds. DESCRIPTION OF EMBODIMENTS [0020] Examples of the liquid carrier include alcohols [0016] Flubendiamide, which is one of the active ingredi including monohydric alcohols, such as methanol, ethanol, ents of the agricultural and horticultural insecticide compo propanol, isopropanol and butanol, and polyhydric alcohols, sition of the present invention, can be produced according to such as ethylene glycol, diethylene glycol, propylene glycol, the production method disclosed in Patent Literature 1 etc., hexylene glycol, polyethylene glycol, polypropylene glycol but commercial formulations thereof are also available for and glycerin; polyol compounds, such as propylene glycol purchase. The other active ingredient(s), dichlorvos (also ether; ketones, such as acetone, methyl ethyl ketone, methyl called DDVP) and profenofos, can be produced according to isobutyl ketone, diisobutyl ketone and cyclohexanone; ethers, the production method disclosed in Patent Literature 6 and 7, such as ethyl ether, dioxane, ethylene glycol monoethyl ether, but commercial formulations thereof are also available for dipropyl ether and tetrahydrofuran; aliphatic hydrocarbons, purchase. These compounds, an appropriate inactive carrier such as normal paraf?n, naphthene, isoparaf?n, kerosene and and a surfactant, and if needed an adjuvant are blended in an mineral oil; aromatic hydrocarbons, such as benzene, tolu appropriate ratio, and through the step of dissolution, sepa ene, xylene, solvent naphtha and alkyl naphthalene; haloge ration, suspension, mixing, impregnation, adsorption and/or nated hydrocarbons, such as dichloromethane, chloroform adhesion, are formulated into an appropriate form for appli and carbon tetrachloride; esters, such as ethyl acetate, diiso cation, such as a suspension concentrate (?owable), an emul propyl phthalate, dibutyl phthalate, dioctyl phthalate and si?able suspension concentrate, an emulsi?able concentrate, dimethyl adipate; lactones, such as gamma-butyrolactone; a soluble concentrate, a wettable powder, a water-dispersible amides, such as dimethylformamide, diethylformamide, dim granule, a granule, a dust, a microcapsule, a capsule, a tablet, ethylacetamide and N-alkyl pyrrolidone (N-methylpyrroli ajumbo and a pack. done etc.); nitriles, such as acetonitrile; sulfur compounds, [0017] The total content of the active ingredients in the such as dimethyl sulfoxide; vegetable oils, such as soybean agricultural and horticultural insecticide composition of the oil, rapeseed oil, cotton seed oil and castor oil; and water. present invention can be adjusted as needed without particu These liquid carriers may be used alone or in a combination of lar limitation, but is usually about 0.01 to 90 parts by mass. two or more kinds. For example, in the case where the agricultural and horticul [0021] Examples of the adjuvant include surfactants used tural insecticide composition is a dust or a granule, the total as a dispersant, a wetting agent, a spreader, a sticking/spread content of the active ingredients is preferably about 0.1 to 30 ing agent, etc., binders, tacki?ers, thickeners, colorants, anti parts by mass, and in the case where the agricultural and freeZing agents, anti-caking agents, disintegrants and stabi horticultural insecticide composition is an emulsi?able con liZing agents. If needed, preservatives, plant fragments, etc. centrate, a wettable powder, a ?owable, a water-dispersible may be additionally used. These adjuvants may be used alone granule or the like, the total content of the active ingredients or in a combination of two or more kinds. is preferably about 0.1 to 60 parts by mass. The blending ratio [0022] Examples of the surfactants used as a dispersant, a of the active ingredients ?ubendiamide and dichlorvos and/ or wetting agent, a spreader, a sticking/spreading agent, etc. profenofos in the agricultural and horticultural insecticide include nonionic surfactants, such as sorbitan fatty acid ester, composition of the present invention is appropriately selected polyoxyethylene sorbitan fatty acid ester, sucrose fatty acid from the range of 0.1 to 10 parts by mass of dichlorvos and/or ester, polyoxyethylene fatty acid ester, polyoxyethylene resin profenofos per part by mass of ?ubendiamide. acid ester, polyoxyethylene fatty acid diester, polyoxyethyl [0018] As for these active ingredients, their commercial ene alkyl ether, polyoxyethylene alkyl aryl ether, polyoxyeth formulations may be used as they are. Alternatively, the active ylene alkyl phenyl ether, polyoxyethylene dialkyl phenyl ingredients can be prepared into separate formulations or a ether, polyoxyethylene alkyl phenyl ether-formaldehyde con combined formulation. For the preparation of a formulation, densates, polyoxyethylene-polyoxypropylene block copoly the active ingredient(s) and an appropriate inactive carrier, mers, polystyrene-polyoxyethylene block polymers, alkyl and if needed an adjuvant are blended in an appropriate ratio, polyoxyethylene-polypropylene block copolymer ether, and through the step of dissolution, separation, suspension, polyoxyethylene alkylamine, polyoxyethylene fatty acid mixing, impregnation, adsorption and/or adhesion, are for amide, polyoxyethylene fatty acid bis(phenyl ether), poly mulated into an appropriate form for application, such as a alkylene benzyl phenyl ether, polyoxyalkylene styryl phenyl US 2014/0256687 A1 Sep. 11,2014
ether, acetylene diol, polyoxyalkylene-added acetylene diol, oxidants, such as phenolic compounds, amine compounds, polyoxyethylene ether-type silicone, ester-type silicone, sulfur compounds and phosphoric acid compounds; and ?uorosurfactants, polyoxyethylene castor oil and polyoxy ultraviolet absorbers, such as salicylic acid compounds and ethylene hydrogenated castor oil; benzophenone compounds. Examples of the preservatives anionic surfactants, such as alkyl sulfates, polyoxyethylene include potassium sorbate and 1,2-benzothiazolin-3-one. alkyl ether sulfates, polyoxyethylene alkyl phenyl ether sul [0029] Further, other adjuvants including functional fates, polyoxyethylene styryl phenyl ether sulfates, alkylben spreading agents, activity enhancers such as metabolic inhibi zene sulfonates, alkylaryl sulfonates, lignosulfonates, alkyl tors (piperonyl butoxide etc.), antioxidants (BHT etc.) and sulfosuccinates, naphthalene sulfonates, alkylnaphthalene ultraviolet absorbers can also be used if needed. sulfonates, salts of naphthalenesulfonic acid-formaldehyde [0030] The “crops” for which the agricultural and horticul condensates, salts of alkylnaphthalenesulfonic acid-formal tural insecticide composition of the present invention can be dehyde condensates, fatty acid salts, polycarboxylic acid used is not particularly limited, and the examples include salts, polyacrylates, N-methyl-fatty acid sarcosinates, cereals such as rice, barley, wheat, rye, oats, corn and sor resinates, polyoxyethylene alkyl ether phosphates and poly ghum; legumes such as soybeans, azuki beans, broad beans, oxyethylene alkyl phenyl ether phosphates; green peas and peanuts; fruit trees and fruits such as apples, cationic surfactants including alkyl amine salts, such as lauryl mandarin oranges, oranges, lemons, limes, grapefruits, Chi amine hydrochloride, stearyl amine hydrochloride, oleyl nese quinces, quinces, pears, European pears, Japanese pears, amine hydrochloride, stearyl amine acetate, stearyl amino grapes, blueberries, cranberries, blackberries, raspberries, propyl amine acetate, alkyl trimethyl ammonium chloride strawberries, peaches, Japanese plums, nectarines, Japanese and alkyl dimethyl benzalkonium chloride; and amphoteric apricots, cherries, apricots, prunes, walnuts, hazelnuts, surfactants, such as amino acid-type or betaine-type ampho almonds, pistachio nuts, cashew nuts, macadamia nuts, teric surfactants. These surfactants may be used alone or in a bananas, persimmons, olives, loquats, date palms, coconut combination of two or more kinds. palms and oil palms; vegetables such as cabbages, tomatoes, [0023] Examples of the binders or the tacki?ers include spinach, broccoli, lettuce, onions, welsh onions, green pep carboxymethyl cellulose and salts thereof, dextrin, soluble pers, eggplants, kohlrabi, Chinese cabbages, leaf mustard, starch, xanthan gum, guar gum, sucrose, polyvinyl pyrroli cauli?ower, garland chrysanthemum, artichoke, asparagus, done, gum arabic, polyvinyl alcohol, polyvinyl acetate, carrots, parsley, celery, parsnips and chard; root vegetables sodium polyacrylate, polyethylene glycols with an average such as carrots, burdock roots, potatoes, sweet potatoes, J apa molecular weight of 6,000 to 20,000, polyethylene oxides nese yam, taro, Japanese radishes, lotus roots and tumips; with an average molecular weight of 100,000 to 5,000,000, crops for processing such as cotton, hemp, paper mulberry, phospholipids (for example, cephalin, lecithin, etc.), cellu oriental paperbush, rapeseeds, oil palms, Barbados nuts, lose powder, dextrin, modi?ed starch, polyaminocarboxylic buckwheat, beet, hops, sugarcane, sugar beet, olives, rubber, acid chelating compounds, cross-linked polyvinyl pyrroli coffee, tobacco, mulberry and tea; gourd such as Japanese done, maleic acid-styrene copolymers, (meth)acrylic acid pumpkins, cucumbers, zucchini, waterrnelons and melons; copolymers, half esters of polyhydric alcohol polymer and pasture grass such as orchard grass, sorghum, timothy, clover dicarboxylic anhydride, water soluble polystyrene sul and alfalfa; fonates, para?in, terpene, polyamide resins, polyacrylates, lawn grass such as Japanese lawn grass, Korean lawn grass, polyoxyethylene, waxes, polyvinyl alkyl ether, alkylphenol Bermuda grass, redtop, creeping bentgrass, colonial bent formaldehyde condensates and synthetic resin emulsions. grass, Kentucky bluegrass, rough bluegrass, tall fescue, [0024] Examples of the thickeners include water soluble chewings fescue, creeping red fescue, annual ryegrass, peren polymers, such as xanthan gum, guar gum, diutan gum, car nial ryegrass, orchard grass and timothy grass; spice and boxymethyl cellulose, polyvinyl pyrrolidone, carboxyvinyl aromatic crops such as lavender, rosemary, thyme, parsley, polymers, acrylic polymers, starch derivatives and polysac pepper, red pepper, Japanese horseradish, ginger, garlic, charides; and inorganic ?ne powders, such as high grade shiso, mint and basil; ?oweringplants such as rose, carnation, bentonite and fumed silica (white carbon). chrysanthemum, lisianthus, baby’s breath, sun?ower, ger [0025] Examples of the colorants include inorganic pig bera, marigold, salvia, petunia, verbena, tulip, aster, gentian, ments, such as iron oxide, titanium oxide and prussian blue; lily, pansy, cyclamen, orchid, lily of the valley, lavender, and organic dyes, such as alizarin dyes, azo dyes and metal stock, omamental kale, primula, poinsettia, gladiolus, catt phthalocyanine dyes. leya, daisy, verbena, cymbidium and begonia; and trees such [0026] Examples of the antifreeZing agents include poly as Japanese ash, birch, ?owering dogwood, eucalyptus, hydric alcohols, such as ethylene glycol, diethylene glycol, ginkgo, lilac, maple, live oak, poplar, Chinese redbud, Chi propylene glycol and glycerin. nese sweet gum, plane, Japanese zelkova, Japanese Thuja, [0027] Examples of the adjuvants serving to prevent caking Momi ?r, southern Japanese hemlock, temple juniper, pine, or facilitate disintegration include polysaccharides (starch, spruce, Japanese yew, elm, buckeye, sweet Viburnum, Bud alginic acid, mannose, galactose, etc.), polyvinyl pyrroli dhist pine, Japanese cedar, Japanese cypress, croton, Japa done, fumed silica (white carbon), ester gum, petroleum nese spindle and Japanese phalinia. resin, sodium tripolyphosphate, sodium hexametaphosphate, [0031] The “crops” include crops provided with a useful metal stearates, cellulose powder, dextrin, methacrylate trait by a classical breeding technique and a recently copolymers, polyvinyl pyrrolidone, polyaminocarboxylic advanced gene recombination technique, for example, acid chelating compounds, sulfonated styrene-isobutylene genetically modi?ed crops (e.g., herbicide-tolerant crops, maleic anhydride copolymers and starch-polyacrylonitrile insect pest-resistant transgenic crops producing insecticidal graft copolymers. proteins, disease-resistant transgenic crops producing induc [0028] Examples of the stabiliZing agents include desic ers of disease resistance, palatability-enhanced crops, long cants, such as zeolite, quicklime and magnesium oxide; anti term preservable crops, high-yield crops, etc.). US 2014/0256687 A1 Sep. 11,2014
[0032] Exemplary crops provided with herbicide tolerance Examples of the foregoing toxins and genetically modi?ed by a classical breeding technique include varieties of rape crops capable of synthesizing these toxins are described in seed, wheat, sun?ower, rice and corn tolerant to the imida EP-A-0374753, WO 93/07278, WO 95/34656, EP-A zolinone family of ALS-inhibiting herbicides such as 0427529, EP-A-451878, WO 03/052073, etc. The toxins con imazethapyr, and such crops are sold under the trade name of tained in such genetically modi?ed crops are suitable for Clear?eld (registered trademark). Also included is a variety control of pests, in particular, Coleopteran insect pests, of soybean provided with tolerance to the sulfonyl urea fam Dipteran insect pests and Lepidopteran insect pests, and due ily of ALS-inhibiting herbicides such as thifensulfuron-me to the toxins, the crops exhibit resistance to such pests. thyl by a classical breeding technique, and this is sold under [0036] Genetically modi?ed crops which express one or the trade name of STS soybean. Also included are crops more of the insecticidal toxins are already known, and some provided with tolerance to acetyl-CoA carboxylase inhibitors of them are commercially available. Examples of such geneti such as trione oxime herbicides and aryloxy phenoxy propi cally modi?ed crops include YieldGard (registered trade onic acid herbicides by a classical breeding technique, for mark), which is a variety of corn expressing a CrylAb toxin; example, SR corn and the like. YieldGard Rootworm (registered trademark), which is a vari [0033] Exemplary crops provided with herbicide tolerance ety of corn expressing a Cry3Bb1 toxin; YieldGard Plus (reg by a gene recombination technique include glyphosate-toler istered trademark), which is a variety of corn expressing ant varieties of corn, soybean, cotton, rapeseed and sugarbeet, CrylAb and Cry3Bb1 toxins; Herculex I (registered trade and such crops are sold under the trade names such as mark), which is a variety of corn expressing a CrylFa2 toxin Roundup Ready (registered trademark) and Agrisure GT. and phosphinothricin N-acetyltransferase (PAT) for tolerance Also included are varieties of corn, soybean, cotton and rape to glufosinate; NuCOTN33B (registered trademark) and seed genetically engineered to be tolerant to glufosinate, and Bollgardl (registered trademark), which are varieties of cot such crops are sold under the trade name of LibertyLink ton expressing a Cry1Ac toxin; Bollgard 11 (registered trade (registered trademark) etc.Also included is a variety of cotton mark), which is a variety of cotton expressing Cry1Ac and genetically engineered to be tolerant to bromoxynil, and this Cry2Ab toxins; VIPCOT (registered trademark), which is a is sold under the trade name of BXN. variety of cotton expressing aVlP toxin; NewLeaf (registered [0034] Crops provided with tolerance to acetyl-CoA car trademark), which is a variety of potato expressing a Cry3A boxylase inhibitors are described in Proc. Natl. Acad. Sci. toxin; NatureGard (registered trademark) Agrisure (regis USA, 87, 7175-7179 (1990), and the like. Further, acetyl tered trademark) GT Advantage (a GA21 glyphosate-tolerant CoA carboxylase mutants resistant to acetyl-CoA carboxy trait), Agrisure (registered trademark) CB Advantage (a Bt11 lase inhibitors are reported in Weed Science, 53, 728-746 corn borer (CB) trait); and Protecta (registered trademark). (2005), and the like, and by introducing the gene of such an [0037] Further, the “crops” also include crops genetically acetyl-CoA carboxylase mutant into crops by a gene recom engineered to produce selectively acting anti-pathogenic sub bination technique, or introducing a resistance-conferring stances. Examples of the anti-pathogenic substances include mutation into acetyl-CoA carboxylase of crops, crops toler PR proteins (PRPs; described in EP-A-03 92225); ion channel ant to acetyl-CoA carboxylase inhibitors can be engineered. inhibitors, such as sodium channel inhibitors and calcium Alternatively, by introducing a nucleic acid causing base channel inhibitors (for example, KPl, KP4 and KP6 toxins, substitution mutation into crop plant cells (a typical example which are produced in viruses, are known); stilbene synthase; of this technique is chimeraplasty technique (Gura T. 1999. bibenzyl synthase; chitinase; glucanase; and substances pro Repairing the Genome’s Spelling Mistakes. Science 285: duced by microbes, such as peptide antibiotics, heterocyclic 316-318.)) to allow site-speci?c substitution mutation in the antibiotics and plant disease resistance-related protein factors amino acids encoded by an acetyl-CoA carboxylase gene of (referred to as plant disease resistance genes and described in crops, crops tolerant to acetyl-CoA carboxylase inhibitors WO 03/000906). Examples of the foregoing anti-pathogenic can be engineered. substances and genetically modi?ed crops capable of produc [0035] The “crops” also include crops genetically engi ing these substances are described in EP-A-0392225, WO neered to synthesize insecticidal toxins etc. Exemplary insec 95/33818, EP-A-0353191, etc. ticidal toxins expressed in such genetically modi?ed crops [0038] Further, the “crops” also include crops provided include insecticidal proteins derived from Bacillus cereus or with a useful trait such as an improved proportion of oil Bacillus papilliae; Bacillus Zhuringiensis-derived delta-en components and a higher amino acid content by a gene dotoxins, such as CrylAb, CrylAc, CrylF, CrylFa2, recombination technique. Examples of such crops include Cry2Ab, Cry3A, Cry3Bb1 and Cry9C, and other insecticidal VlSTlVE (registered trademark), which is a variety of soy proteins, such as VlPl, VlP2, VlP3 and VlP3A; nematode bean engineered to have a reduced linolenic acid content, and derived insecticidal proteins; toxins produced by animals, high-lysine (or high-oil) corn, which is a variety of corn such as scorpion toxins, spider toxins, bee toxins and insect engineered to have an increased content of lysine or oil. speci?c neurotoxins; toxins of ?lamentous fungi; plant lec [0039] Furthermore, the “crops” also include stacked vari tins; agglutinin; protease inhibitors, such as trypsin inhibi eties with a combination of two or more selected from the tors, serine protease inhibitors, patatin, cystatin and papain above-described classical herbicide-tolerant traits, herbicide inhibitors; ribosome inactivating proteins (RIP), such as ricin, tolerant genes, insecticidal pest-resistance genes, anti-patho maize RIP, abrin, saporin and bryodin; steroid metabolizing genic substance-producing genes and useful traits including enzymes, such as 3-hydroxy steroid oxidase, ecdysteroid an improved proportion of oil components and a higher amino UDP-glucosyltransferase and cholesterol oxidase; ecdysone acid content. When the agricultural and horticultural insecti inhibitors; HMG-CoA reductase; ion channel inhibitors, such cide composition of the present invention is used for crops as sodium channel inhibitors and calcium channel inhibitors; modi?ed to be tolerant to a herbicide, systematic and/or juvenile hormone esterase; diuretic hormone receptors; stil mixed treatment with the herbicide (for example, glyphosate bene synthase; bibenzyl synthase; chitinase; and glucanase. or its salts, glufosinate or its salts, dicamba or its salts, US 2014/0256687 A1 Sep. 11,2014
imazethapyr or its salts, isoxa?utole, etc.) and the agricultural rated into bed soil, covering soil or the whole soil. Simply, soil and horticultural insecticide composition of the present and such a formulation may be alternately layered. In the invention can control weeds and insect pests in an integrated application at the seeding time, the timing of the application manner. may be before, at the same time as, or after seeding, or after [0040] In the use of the agricultural and horticultural insec covering with soil. In the case of paddy rice, submerged ticide composition of the present invention, the above-de application of a granule etc. to a paddy ?eld is often per scribed formulation(s) containing an active ingredient(s) formed. is/are optionally diluted or suspended in water etc., and insect [0045] For ?eld crops, such as potato, sweet potato and pests are directly treated with, or target crops potentially soybean, preferred is treatment of their seeds, cultivation infested with the insect pests, seeds of the target crops, soil or media in the vicinity of plants, or the like in the period of cultivation medium for planting the seeds, or the like are seeding to seedling culture. For plants of which the seeds are treated with the optionally diluted or suspended formulation directly sown in the ?eld, in addition to direct seed treatment, (s) in an amount (s) effective for insect pest control according treatment of cultivation media in the vicinity of plants or the to a usual method. Examples of the treatment method include like during cultivation is preferable. Speci?cally, the treat spray treatment of foliage etc., treatment of nursery boxes for ment can be performed by, for example, applying a granule paddy rice, seed treatment such as dust coating, dipping and onto soil, or drenching soil with a formulation in a water disinfection of seeds, planting hole treatment, plant foot treat diluted or undiluted liquid form. ment, planting row treatment, drench treatment and soil [0046] In the case of culture plants to be transplanted, incorporation treatment. Also included is treatment of water examples of the treatment in the period of seeding to seedling culture media in hydroponics. culture include, in addition to direct seed treatment, drench [0041] The seed treatment may be performed in a usual treatment of nursery beds for seedlings with a formulation in manner. The exemplary methods include dipping of seeds in a liquid form; and granule application to nursery beds for a diluted or undiluted ?uid of a liquid or solid formulation for seedlings. Also included are treatment of planting holes with the permeation of agrochemicals into the seeds; mixing, dust a granule; and incorporation of a granule into cultivation coating or other treatment of seeds with a liquid or solid media in the vicinity of planting points at the time of ?x formulation for the adherence of agrochemicals onto the sur planting. faces of the seeds; monolayer or multilayer coating of seeds [0047] For the above-described treatment, a ?ubendiamide with a mixture of a liquid or solid formulation and a highly single formulation and a dichlorvos or profenofos single for adhesive carrier such as resins and polymers; and application mulation can be used after mixed with each other on site, and of a liquid or solid formulation to the vicinity of seeds at the such a use can also produce the desired insecticidal effect. same time as seeding. The term “seed” used in the seed Alternatively, for the above-described treatment, the two treatment is, in a broad sense, synonymous with a plant body single formulations canbe separately used in the same period, used for propagation. The examples include, in addition to a and such a use can also produce the desired insecticidal effect. so-called seed, a plant body for vegetative propagation, such The term “the same period” does not mean that treatments as a bulb, a tuber, a seed potato, a discoid stem and a stem used with the two single formulations are performed at the exact for cuttage. same time, and in the case where treatments with the two [0042] In the method of the present invention, the term single formulations are performed within a time frame of “soil” or “cultivation medium” refers to support medium for about one week, the treatments can be regarded as being plant cultivation and the materials are not particularly limited performed “in the same period.” Further, each treatment can as long as plants can grow. Examples of the support medium be performed by a different method. Alternatively, for the include so-called soils of various kinds, seedling mats and above-described treatment, the two single formulations can water, and also include sand, vermiculite, cotton, paper, be separately used at a given interval, and such a use can also diatomite, agar, gelatinous substances, high-molecular produce the desired insecticidal effect. The interval between weight substances, rock wool, glass wool, wood chip, bark the treatments is not particularly limited as long as the effect and pumice. of the present invention can be exerted, but in general, the [0043] Exemplary methods of soil application include interval is preferably 3 months or less, and particularly pref application of a water-diluted or undiluted liquid or solid erably 2 months or less. In this case, the ?rst treatment may be formulation to the vicinity of planting points, nursery beds for performed with any of the active ingredients and each treat seedlings, or the like; application of a granule to the vicinity ment may be performed by a different method. of planting points or nursery beds; application of a dust, a [0048] In recent years, IPM (integrated pest management) wettable powder, a water-dispersible granule, a granule or the technology using insect sex pheromones (e.g., communica like onto soil and subsequent incorporation of the formulation tion disrupting agents against Tortricidae and Hadeninae, into the whole soil before seeding or transplanting; and appli etc.), natural enemy insects, etc. has made progress, and this cation of a dust, a wettable powder, a water-dispersible gran technology and the composition of the present invention can ule, a granule or the like to planting holes, planting rows or the be used in combination or used systematically. like before seeding or planting. [0049] The amount of the agricultural and horticultural [0044] To nursery boxes for paddy rice, for example, a dust, insecticide composition used for treatment may vary with a water-dispersible granule, a granule or the like can be various factors, for example, the purpose, the target insect applied, although the suitable formulation may vary depend pest, the crop growing conditions, the weather, the environ ing on the application time, in other words, depending on the mental conditions, the formulation, the application method, cultivation stage such as seeding time, greening period and the application site, the application time, etc., but for planting time. In the soil application, a formulation such as a example, the amounts of the active ingredient compounds are dust, a water-dispersible granule, a granule or the like may be as follows: in the case of spray treatment, 1 to 200 g/ha of mixed with soil. For example, such a formulation is incorpo ?ubendiamide and 100 to 2000 g/ha of dichlorvos and/or US 2014/0256687 A1 Sep. 11,2014
profenofos are applied to target crops; and in the case of soil Papilio helenus, Colias erate poliographus, Phalera ?ave treatment or drench treatment, 1 to 100 g/ ha of ?ubendiamide scens, species of the family Pieridae such as Pieris rapae, and 50 to 1000 g/ha of dichlorvos and/ or profenofos are Euproctis similis, Acrolepiopsis suzukiella, Ostrinia nubila applied onto or in?ltrated into the surrounding soil of target lis, Mamestra brassicae, Ascotis selenaria, Phtheochroides crops. clandestina, Hoshinoa adumbratana, Odonestisprunijapon [0050] The agricultural and horticultural insecticide com ensis, Triaena intermedia, Adoxophyes oranafasciata, Gra position of the present invention is suitable for controlling a pholita inopinata, Spilonota ocellana, Spilonota lechriaspis, variety of insect pests Which may damage paddy rice, veg Illiberispruni, Argyresthia conjugella, Caloptilia zachrysa, etables, fruits, other ?owering plants, etc. The insect pests to Archips breviplicanus, Anomis ?ava, Pectinophora gossyp be controlled are, for example, agricultural and forest pests, iella, Notarcha derogata, Diaphania indica, Heliothis vire horticultural pests, stored grain pests, sanitary pests, nema scens and Earias cupreoviridis; todes, etc. The speci?c examples include the following: species of the Order Hemiptera such as Nezara antennata, species of the Order Lepidoptera such as Parasa consocia, Stenotus rubrovittatus, Graphosoma rubrolineatum, Trigo Anomis mesogona, Papilio xuthus, Matsumuraeses notylus coelestialium, Aeschynteles maculatus, Creontiades azukivora, Ostrinia scapulalis, Spodoptera exempta, pallidifer, Dysdercus cingulatus, Chrysomphalus ?cus, Hyphantria cunea, Ostrinia furnacalis, Pseudaletia sepa Aonidiella aurantii, Graptopsaltria nigrofuscata, Blissus rata, Til’lELl translucens, Bactra furfurana, Parnara guttata, leucopterus, Iceryapurchasi, Piezodorus hybneri, Lagynoto Marasmia exigua, Parnara guttata, Sesamia inferens, Broch mus elongatus, Thaia subrufa, Scotinophara lurida, Sitobion mia triannulella, Monema?avescens, Trichoplusia ni, Pleu ibarae, Stariodes iwasakii, Aspidiotus destructor, Taylorily roptya ruralis, Cystidia couaggaria, Lampides boeticus, gus pallidulus, Myzus mumecola, Pseudaulacaspis pruni Cephonodes hylas, Helicoverpa armigera, Phalerodonta cola, Acyrthosiphon pisum, Anacanthocoris striicornis, manleyi, Eumeta japonica, Pieris brassicae, Malacosoma Ectometopterus micantulus, Eysarcoris lewisi, neustria testacea, Molipteryx fulginosa, Cicadella viridis, Rhopalosophum Stathmopoda masinissa, Cuphodes diospyrosella, Archips ru?abdominalis, Saissetia oleae, Trialeurodes vaporari xylosteanus, Agrotis segetum, Tetramoera schistaceana, orum, A guriahana quercus, Lygus sp., Euceraphispunctipen Papilio machaon hippocrates, Endoclyta sinensis, Lyonetia nis, Andaspis kashicola, Coccus pseudomagnoliarum, Cav prunifoliella, Phyllonorycter ringoneella, Cydia kurokoi, elerius saccharivorus, Galeatus spinifrons, Eucoenogenes aestuosa, Lobesia botrana, Latoia sinica, Macrosiphoniella sanborni, Aonidiella citrina, Halyomor Euzophera batangensis, Phalonidia mesotypa, Spilosoma pha mista, Stephanitisfasciicarina, Trioza camphorae, Lep imparilis, Glyphodespyloalis, Olethreutes mori, Hneola bis tocorisa chinensis, Trioza quercicola, Uhlerites latius, Eryth selliella, Endoclyta excrescens, roneura comes, Paromius exguus, Duplaspidiotus claviger, Nemapogon granellus, Synanthedon hector, Cydia Nephotettix nigropictus, Halticiellus insularis, Perkinsiella pomonella, Plutella xylostella, Cnaphalocrocis medinalis, saccharicida, Psylla malivorella, Sesamia calamistis, Scirpophaga incertulas, Pediasia teter Anomomeura mori, Pseudococcus longispinis, Pseudaula rellus, Phthorimaea operculella, Stauropus fagi persimilis, caspis pentagona, Pulvinaria kuwacola, Apolygus lucorum, Etiella Zinckenella, Spodoptera exigua, Palpifer sexnotata, Togo hemipterus, Toxoptera aurantii, Saccharicoccus sac Spodoptera manuritia, Scirpophaga innotata, Xestia c-ni chari, Geoica lucifuga, Numata muiri, Comstockaspisperni grum, Spodoptera depravata, Ephestia kuehniella, Angerona ciosa, Unaspis citri, Aulacorthum solani, Eysarcoris ventra prunaria, Clostera anastomosis, Pseudoplusia includens, lis, Bemisia argentifolii, Cicadella spectra, Aspidiotus Matsumuraeses falcana, Helicoverpa assulta, Autographa hederae, Liorhyssus hyalinus, Calophya nigridorsalis, Soga nigrisigna, Agrotis ipsilon, Euproctis pseudoconspersa, tellafurcifera, Megoura crassicauda, Brevicoryne brassicae, Adoxophyes orana, Caloptilia theivora, Homona magn Aphis glycines, Leptocorisa oratorius, Nephotettix virescens, anima, Uroeuconformosanum, Cyrtopeltis tennuis, Bemisia tabaci, Lecanium persicae, Parlatoria theae, Pseudaonidia paeo Ephestia elutella, Eumeta minuscula, Clostera anachoreta, niae, Empoasca onukii, Plautia stali, Dysaphis tulipae, Mac Heliothis maritima, Sparganothispilleriana, Busseolafusca, rosiphum euphorbiae, Stephanitis pyrioides, Ceroplastes Euproctis sub?ava, Biston robustum, Heliothis zea, Aedia ceriferus, Parlatoria camelliae, Apolygus spinolai, Nephotet leucomelas, Narosoideus?avidorsalis, Vlminia rumicis, Buc tix cincticeps, Glaucias subpunctatus, Orthotylus?avospar culatrix pyrivorella, Grapholita molesta, Spulerina astau sus, Rhopalosiphum maidis, Peregrinus maidis, Eysarcoris rota, Ectomyelois pyrivorella, Chilo suppressalis, Acrolepi parvus, Cimex lectularius, Psylla abieti, Nilaparvata lugens, opsis sapporensis, Plodia interpunctella, Hellula undalis, Psylla tobirae, Eurydema rugosum, Schizophis piricola, Sitotroga ceralella, Spodoptera litura, a species of the family Psylla pyricola, Parlatoreopsis pyri, Stephanitis sashi, Dys Tortricidae (Eucosma aporema), Acleris comariana, micoccus wistariae, Lepholeucaspis japonica, Sappaphis Scopelodes contracus, Orgyia thyellina, Spodoptera fru piri, Lipaphis erysimi, Neotoxopteraformosana, Rhopaloso giperda, Ostrinia zaguliaevi, Naranga aenescens, Andraca phum nymphaeae, Edwardsiana rosae, Pinnaspis aspidis bipunctata, Paranthrene regal is, Acosmeryx castanea, trae, Psylla alni, Speusotettix subfusculus, Alnetoidia alneti, Phyllocnistis toparcha, Endopiza viteana, Eupoecillia Sogatella panicicola, Adelphocoris lineolatus, Dysdercus ambiguella, Anticarsia gemmatalis, Cnephasia cinereipal poecilus, Parlatoria Ziziphi, Uhlerites debile, Laodelphax pana, Lymantria dispar, Dendrolimus spectabilis, Legumini striatellus, Eurydemapulchrum, Cletus trigonus, Clovia vora glycinivorella, Maruca testulalis, Matsumuraeses punctata, Empoasca sp., Coccus hesperidum, Pachybrachius phaseoli, Caloptilia soyella, Phyllocnistis citrella, Hadylepta luridus, Planococcus kraunhiae, Stenotus binotatus, Arbo indicata, Archips fuscocupreanus, Acanthoplusia agnata, ridia apicaris, Macrostelesfasci?’ons, Dolycoris baccarum, Bambalina sp., Carposina niponensis, Conogethes punc Adelphocoris triannulatus, Vlteus vitifolii, Acanthocoris sor tiferalis, Synanthedon sp., Lyonetia clerkella, didus, Leptocorisa acuta, US 2014/0256687 A1 Sep. 11,2014
Macropes obnubilus, Cletus puncliger, Riplorlus clavalus, Zicola, Liriomyza chinensis, Culex quinquefascialus, Aedes Paralrioza cockerelli, Aphrophora coslalis, Lygus disponsi, aegypli, Aedes albopiclus, Liriomyza Zrifolii, Dacus dorsal is, Lygus saundersi, Crisicoccus pini, Empoasca abielis, Crisi Dacus Zsuneonis, Silodiplosis m0sellana, Meromuza coccus malsumoloi, Aphis craccivora, Megacopla punclalis nigrivenlris, Anaslrepha ludens and Phagolelis pomonella; simum, Eysarcoris gulliger, Lepidosaphes beckii, Diaphorina species of the Order Hymenoptera such as Prislomyrmex cilri, Toxoplera cilricidus, Planococcus cilri, Dialeurodes pungens, species of the family Bethylidae, Monomorium cilri, Aleurocanlhus spiniferus, Pseudococcus cilriculus, pharaosis, Pheidole noda, Alhalia rosae, Dryocosmus Zyginella cilri, Pulvinaria cilricola, Coccus discrepans, kuriphilus, Formica fusca japonica, species of the subfamily Pseudaonidia duplex, Pulvinaria auranlii, Lecanium corni, Vespinae, Alhalia infumala infumala, Arge pagana, Alhalia Nezara viridula, Slenodema calcaralum, Rhopalosiphum japonica, Acromyrmex spp., Solenopsis spp., Arge mali and padi, Silobion akebiae, Ochelellus glaber; Schizaphis graminum, Sorhoanus Zrilici, Brachycaudus heli species of the Order Orthoptera such as Homorocoryphus chrysi, Carpocoris purpureipennis, Myzus persicae, Hya lineosus, Gryllolalpa sp., Oxya hyla inlricala, Oxya yezoen lopleruspruni, Aphis farinoseyanagicola, Melasalispopuli, sis, Locusla migratoria, Oxya japonica, Homorocoryphus Unaspis yanonensis, Mesohomoloma camphorae, Aphis spi jezoensis and Teleogryllus emma; raecola, Aphis pomi, Lepidosaphes ulmi, Psylla mali, Hel species of the Order Thysanoptera such as Selenolhrips erocordylus?avipes, Myzus malisuclus, Aphidonuguis mali, rubrocinclus, Slenchaelolhrips biformis, Haplolhrips Orienlus ishidai, Ovalus malicolens, Eriosoma lanigerum, aculealus, Ponliculolhrips diospyrosi, Thrips?avus, Anapho Ceroplasles rubens and Aphis gossypii; Zhrips obscurus, Liolhrips?oridensis, Thrips simplex, Thrips species of the Order Coleoptera such as Xyslrocera globosa, nigropilosus, Heliolhrips haemorrhoidalis, Pseudodendro Paederusfuscipes, Eucelonia roelofsi, Callosobruchus chin Zhrips m0ri, Microcephalolhrips abdominalis, Leeuwenia ensis, Cylas formicarius, Hypera poslica, Echinocnemus pasanii, Lilolelolhrips pasaniae, Scirlolhrips cilri, Haplo squameus, Oulema oryzae, Donacia provosli, Lissorhoplrus Zhrips chinensis, Myclerolhrips glycines, Thrips selosus, Scir oryzophilus, Colasposoma dauricum, Euscepes poslfascia Zolhrips dorsalis, Dendrolhrips minowai, Haplolhrips niger, Zus, Epilachna variveslis, Acanlhoscelides obleclus, Thrips Zabaci, Thrips alliorum, Thrips hawaiiensis, Haplo Diabrolica virgifera virgifera, Involvulus cupreus, Aula Zhrips kurdjumovi, Chirolhrips manicalus, Frankliniella cophorafemoralis, Bruchuspisorum, Epilachna viginlioclo inlonsa, Thrips coloralus, Franklinella occidentalis, Thrips maculala, Carpophilus dimidialus, Cassida nebulosa, palmi, Frankliniella lilivora and Liolhrips vaneeckei; Luperomorpha Zunebrosa, Phyllolrela slriolala, Psacolhea species of the Order Acari such as Leplolrombidium aka hilaris, Aeoleslhes chrysolhrix, mushi, Telranychus ludeni, Dermacenlor variabilis, Telrany Curculio sikkimensis, Carpophilus hemiplerus, Oxycelonia chus Zruncalus, Ornithonyssus bacoli, Demodex canis, Tel jucunda, Diabrolica sp., Mimela splendens, Silophilus zea ranychus viennensis, Telranychus kanzawai, species of the mais, Tribolium caslaneum, Silophilus oryzae, Palorus sub family lxodidae such as Rhipicephalus sanguineus, Cheyl depressus, Melolonlha japonica, Anoplophora malasiaca, eZus malaccensis, Drophagus pulrescenliae, Dermalopha Nealus picipes, Leplinolarsa decemlineala, Diabrolica goidesfarinae, Lalrodeclus hassellii, Dermacenlor Zaiwani undecimpunclala howardi, Sphenophorus venalus, Crioceris cus, Acaphylla Zheavagrans, Polyphagolarsonemus lalus, qualuordecimpunclala, Conolrachelus nenuphar, Ceulho Aculops lycopersici, Ornithonyssus sylvairum, Telranychus rhynchidius albosuluralis, Phaedon brassicae, Lasioderma urticae, Eriophyes chibaensis, Sacroples scabiei, Haema serricorne, Silonajaponicus, Adorelus Zenuimaculalus, Tene physalis longicornis, Ixodes scapularis, Drophagus similis, brio m0li20r, Basilepla balyi, Hypera nigriroslris, Chaeloc Cheylelus erudilus, Panonychus cilri, Cheylelus m00rei, nema concinna, Anomala cuprea, Heplophylla picea, Epil Brevipalpus phoenicis, Oclodecles cynolis, Dermalopha achna viginlioclopunclala, Diabrolica longicornis, goides plrenyssnus, Haemaphysalis ?ava, Ixodes ovalus, Eucelonia pilifera, Agrioles spp., Phyllocoplrula cilri, Aculus schlechlendali, Panonychus Allagenus unicolorjaponicus, Pagria signala, Anomala rufo ulmi, Amblyomma americanum and Dermanyssus gallinae; cuprea, Palorus ralzeburgii, Alphilobius laevigalus, Anthre species of the Order lsoptera such as Reliculilermes nus verbasci, Lyclus brunneus, Tribolium confusum, miyalakei, Incisilermes minor, Coplolermes formosanus, Medylhia nigrobilineala, Xylolrechus pyrrhoderus, Epilrix Hodolermopsis japonica, Reliculilermes sp., Reliculilermes cucumeris, Tomicus piniperda, Monochamus allernalus, ?aviceps amamianus, Glyplolermes kushimensis, Coploler Popillia japonica, Epicaula gorhami, Silophilus zeamais, mes guangzhoensis, Neolermes koshunensis, Glyplolermes Rhynchiles heros, Lislroderes cosliroslris, Callosobruchus kodamai, Glyplolermes salsumensis, Cryptolermes domesti maculalus, Phyllobius armalus, Anthonomus pomorum, cus, Odonlolermes formosanus, Glyplolermes nakajimai, Linaeidea aenea and Anthonomus grandis; Pericaprilermes nilobei and Reliculilermes speralus; species of the Order Diptera such as Culex pipiens pallens, species of the Order Blattodea such as Periplanelafuliginosa, Pegomya hyoscyami, Liriomyza huidobrensis, Musca domes Blallella germanica, Blalla orientalis, Periplanela brunnea, Zica, Chlorops oryzae, Hydrellia sasakii, Agromyza oryzae, Blallella liluricollis, Periplanela japonica and Periplanela Hydrellia griseola, Ophiomyia phaseoli, Dacus cucurbilae, americana; Drosophila suzukii, Rhacochlaenajaponica, Muscina slabu species of the Order Siphonaptera such as Pulex irritans, lans, species of the family Phoridae such as Megaselia spi Clenocephalidesfelis and Ceralophyllus gallinae; racularis, Clogmia albipunclala, lipula aino, Phormia species of the Phylum Nematoda such as Nolholylenchus regina, Culex Zrilaeniorhynchus, Anopheles sinensis, Hyl acris, Aphelenchoides besseyi, Pralylenchus penetrans, emya brassicae, Asphondylia sp., Delia plalura, Delia anti Meloidogyne hapla, Meloidogyne incognila, Globodera ros qua, Rhagolelis cerasi, Culexpipiens m0leslus Forskal, Cer Zochiensis, Meloidogyne javanica, Helerodera glycines, alilis capilala, Bradysia agreslis, Pegomya cunicularia, Pralylenchus cofeae, Pralylenchus negleclus and Hlenchus Liriomyza salivae, Liriomyza bryoniae, Chromalomyia hor semipenelrans; and US 2014/0256687 A1 Sep. 11,2014
species of the Phylum Mollusca such as Pomacea canalicu afen, picoxystrobin, picobenzamide, bithionol, bitertanol, lala, Achalinafulica, Meghimalium bilinealum, Lehmannina hydroxyisoxazole, hydroxyisoxazole-potassium, binapacryl, valenliana, Limacus?avus andAcusZa despecla sieboldiana. biphenyl, piperalin, hymexazol, pyraoxystrobin, pyracar Other agricultural and horticultural insect pests to be con bolid, pyraclostrobin, pyrazophos, pyrametostrobin, pyri trolled are, for example, Tula absolula and the like. ofenone, pyridinitril, pyrifenox, [0051] The agricultural and horticultural insecticide com pyribencarb, pyrimethanil, pyroxychlor, pyroxyfur, pyro position of the present invention can be used simultaneously quilon, Vinclozolin, ferbam, famoxadone, fenapanil, fenami With agricultural and horticultural microbicides, agricultural done, fenaminosulf, fenarimol, fenitropan, fenoxanil, ferim and horticultural insecticides, agricultural and horticultural zone, fentin, fenpiclonil, fenpyrazamine, fenbuconazole, herbicides, synergists, phytotoxicity reducers, etc. for control fenfuram, fenpropidin, fenpropimorph, fenhexamid, phtha of diseases/insect pests, weeds, etc. Which may spread in the lide, buthiobate, butylamine, bupirimate, fuberidazole, blas application period of the composition of the present inven ticidin-S, furametpyr, furalaxyl, ?uacrypyrim, ?uaZinam, ?u tion, enhanced effects and reduced phytotoxicity to crops. oxastrobin, ?uotrimazole, ?uopicolide, ?uopyram, Non-limiting examples of typical compounds used as the ?uoroimide, furcarbanil, ?uxapyroxad, ?uquinconazole, fur agricultural and horticultural microbicides, the agricultural conazole, furconazole-cis, ?udioxonil, ?usilazole, ?usulfa and horticultural insecticides, the agricultural and horticul mide, ?utianil, ?utolanil, ?utriafol, furfural, furrnecyclox, tural herbicides, the synergists or the phytotoxicity reducers ?umetover, ?umorph, proquinaZid, prochloraZ, procymi are listed beloW. done, prothiocarb, [0052] Examples of the agricultural and horticultural prothioconazole, propamocarb, propiconazole, propineb, microbicides include aureofungin, azaconazole, aZithiram, furophanate, probenazole, bromuconazole, hexachlorobuta acypetacs, acibenzolar, acibenzolar-S-methyl, azoxystrobin, diene, hexaconazole, hexylthiofos, bethovain, benalaxyl, anilaZine, amisulbrom, ampropylfos, ametoctradin, allyl benalaxyl-M, benodanil, benomyl, pefurazoate, benquinox, alcohol, aldimorph, amobam, isotianil, isovaledione, isopy penconazole, benzamorf, pencycuron, benzohydroxamic razam, isofetamid, isoprothiolane, ipconazole, iprodione, acid, bentaluron, benthiazole, benthiavalicarb, benthiavali iprovalicarb, iprobenfos, imazalil, iminoctadine, iminocta carb-isopropyl, penthiopyrad, pen?ufen, boscalid, phos dine-albesilate, iminoctadine-triacetate, imibenconazole, diphen, fosetyl, fosetyl-Al, polyoxins, polyoxorim, polycar uniconazole, uniconazole-P, echlomezole, edifenphos, eta bamate, folpet, formaldehyde, machine oil, maneb, conazole, ethaboxam, ethirimol, etem, ethoxyquin, etridiaZ mancozeb, mandipropamid, myclozolin, myclobutanil, mil ole, enestroburin, epoxiconazole, oxadixyl, oxycarboxin, diomycin, milneb, mecarbinZid, methasulfocarb, metazoxo copper-8-quinolinolate, oxytetracycline, copper-oxinate, lon, metam, metam-sodium, metalaxyl, metalaxyl-M, meti oxpoconazole, oxpoconazole-fumarate, oxolinic acid, ram, methyl isothiocyanate, meptyldinocap, metconazole, octhilinone, ofurace, orysastrobin, metam-sodium, metsulfovax, methfuroxam, metominostrobin, metrafenone, kasugamycin, carbamorph, carpropamid, carbendaZim, car mepanipyrim, mefenoxam, meptyldinocap, mepronil, mebe boxin, carvone, quinazamid, quinacetol, quinoxyfen, chi nil, iodomethane, rabenzazole, benzalkonium chloride, inor nomethionat, quinomethionate, captafol, captan, kiralaxyl, ganic microbicides such as basic copper chloride, basic cop quinconazole, quintozene, guazatine, cufraneb, cuprobam, per sulfate and silver, sodium hypochlorite, cupric hydroxide, glyodin, griseofulvin, climbazole, cresol, kresoxim-methyl, wettable sulfur, calcium polysul?de, potassium hydrogen chlozolinate, clotrimazole, chlobenthiazone, chlorani carbonate, sodium hydrogen carbonate, sulfur, copper sulfate formethan, chloranil, chlorquinox, chloropicrin, chloroneb, anhydride, nickel dimethyldithiocarbamate, oxine copper, salicylanilide, zarilamid, cyazofamid, diethyl pyrocarbonate, Zinc sulfate and copper sulfate pentahydrate. diethofencarb, cyclafuramid, diclocymet, dichlozoline, [0053] Examples of the agricultural and horticultural insec diclobutrazol, dichlo?uanid, cycloheximide, diclomeZine, ticides include 3,5-xylyl methylcarbamate (XMC), crystal dicloran, dichlorophen, dichlone, disulfuram, ditalimfos, line protein toxins produced by Bacillus Zhuringiensis such as dithianon, diniconazole, Bacillus Zhuringiensis aizawai, Bacillus Zhuringiensis israe diniconazole-M, Zineb, dinocap, dinocton, dinosulfon, dinot lensis, Bacillus Zhuringiensis japonensis, Bacillus Zhuring erbon, dinobuton, dinopenton, dipyrithione, diphenylamine, iensis kurslaki and Bacillus Zhuringiensis Zenebrionis, difenoconazole, cy?ufenamid, di?umetorim, cyproconazole, BPMC, Bt toxin-derived insecticidal compounds, CPCBS cyprodinil, cyprofuram, cypendazole, simeconazole, dime (chlorfenson), DCIP (dichlorodiisopropyl ether), D-D (1,3 thirimol, dimethomorph, cymoxanil, dimoxystrobin, methyl dichloropropene), DDT, NAC, O-4-dimethylsulfamoylphe bromide, Ziram, silthiofam, streptomycin, spiroxamine, sul nyl 0,0-diethyl phosphorothioate (DSP), O-ethyl O-4-nitro tropen, sedaxane, zoxamide, dazomet, thiadiaZin, tiadinil, phenyl phenylphosphonothioate (EPN), thiadi?uor, thiabendazole, tioxymid, thioquinox, thiochlor tripropylisocyanurate (TPIC), acrinathrin, azadirachtin, aZin fenphim, thiophanate, thiophanate-methyl, thicyofen, thi phos-methyl, acequinocyl, acetamiprid, acetoprole, aceph ?uzamide, thiram, decafentin, tecnazene, tecloftalam, teco ate, abamectin, a?dopyropen, avermectin-B, amido?umet, ram, tetraconazole, debacarb, dehydroacetic acid, amitraZ, alanycarb, aldicarb, aldoxycarb, aldrin, alpha-en tebuconazole, tebu?oquin, dodicin, dodine, dosulfan, alpha-cypermethrin, albendazole, allethrin, isazo dodecyl benzensulfonate bis-ethylene diamine copper(ll) fos, isoamidofos, isoxathion, isofenphos, isoprocarb (MIPC), (DBEDC), dodemorph, drazoxolon, triadimenol, triadime ivermectin, imicyafos, imidacloprid, imiprothrin, indoxac fon, triaZbutil, triazoxide, triamiphos, triarimol, trichlamide, arb, esfenvalerate, ethiofencarb, ethion, ethiprole, etoxazole, tricyclazole, triticonazole, tridemorph, tributyltin oxide, tri ethofenprox, ethoprophos, etrimfos, emamectin, emamectin ?umizole, tri?oxystrobin, triforine, tolyl?uanid, tolclofos benzoate, endosulfan, empenthrin, oxamyl, oxydemeton-me methyl, tolprocarb, natamycin, nabam, nitrostyrene, thyl, oxydeprofos (ESP), oxibendazole, oxfendazole, potas nitrothal-isopropyl, nuarimol, copper nonylphenol sulfonate, sium oleate, sodium oleate, cadusafos, cartap, carbaryl, halacrinate, validamycin, valifenalate, harpin protein, bix carbosulfan, carbofuran, gamma-cyhalothrin, xylylcarb, US 2014/0256687 A1 Sep. 11,2014
quinalphos, kinoprene, chinomethionat, cloethocarb, 4-CPB, 4-CPP, MCP, MCPA, MCPA-thioethyl, MCPB, ioxy clothianidin, clofenteZine, chromafenozide, chlorantranilip nil, aclonifen, azafenidin, aci?uorfen, aZiprotryne, aZimsul role, chlorethoxyfos, chlordimeform, chlordane, chlorpyri furon, asulam, acetochlor, atraZine, atraton, anisuron, anilo fos, chlorpyrifos-methyl, chlorphenapyr, chlorfenson, chlor fos, aviglycine, abscisic acid, amicarbazone, amidosulfuron, fenvinphos, chlor?uazuron, chlorobenZilate, chlorobenzoate, amitrole, aminocyclopyrachlor, aminopyralid, amibuZin, kelthane (dicofol), salithion, cyanophos (CYAP), diafenthi amiprophos-methyl, ametridione, ametryn, alachlor, alli uron, diamidafos, cyantraniliprole, theta-cypermethrin, dochlor, alloxydim, alorac, iofensulfuron, isouron, isocarba dienochlor, cyenopyrafen, dioxabenzofos, diofenolan, mid, isoxachlortole, isoxapyrifop, isoxa?utole, isoxaben, iso sigma-cypermethrin, dichlofenthion (ECP), cycloprothrin, cil, isonoruron, isoproturon, isopropalin, isopolinate, disulfoton, dinotefuran, cyhalothrin, cyphenothrin, isomethiozin, inaben?de, ipaZine, ipfencarbazone, iprymi cy?uthrin, di?ubenzuron, cy?umetofen, di?ovidaZin, dam, imazaquin, imazapic, imazapyr, imazamethapyr, cyhexatin, cypermethrin, dimethylvinphos, dimethoate, imazamethabenZ, imazamethabenZ-methyl, imazamox, dime?uthrin, sila?uofen, cyromaZine, spinetoram, spinosad, imazethapyr, imazosulfuron, indaZi?am, indanofan, indole spirodiclofen, spirotetramat, spiromesifen, sul?uramid, sul butyric acid, uniconazole-P, eglinaZine, esprocarb, ethamet profos, sulfoxa?or, zeta-cypermethrin, diaZinon, sulfuron, ethametsulfuron-methyl, ethal?uralin, ethiolate, tau-?uvalinate, dazomet, thiacloprid, thiamethoxam, thiodi ethychlozate-ethyl, ethidimuron, etinofen, ethephon, ethox carb, thiocyclam, thiosultap, thiosultap-sodium, thionaZin, ysulfuron, ethoxyfen, etnipromid, ethofumesate, etobenza thiometon, deet, dieldrin, tetrachlorvinphos, tetradifon, tet nid, epronaZ, erbon, endothal, oxadiazon, oxadiargyl, ovai ramethyl?uthrin, tetramethrin, tebupirimfos, tebufenozide, clomefone, oxasulfuron, oxapyrazon, oxy?uorfen, oryzalin, tebufenpyrad, te?uthrin, te?ubenzuron, demeton-S-methyl, orthosulfamuron, orbencarb, cafenstrole, cambendichlor, temephos, deltamethrin, terbufos, tralopyril, tralomethrin, carbasulam, carfentrazone, carfentrazone-ethyl, karbutilate, trans?uthrin, triazamate, triazuron, trichlamide, trichlorphon carbetamide, carboxazole, quizalofop, quizalofop-P, quizalo (DEP), tri?umuron, tolfenpyrad, naled (BRP), nithiaZine, fop-ethyl, xylachlor, quinoclamine, quinonamid, quinclorac, nitenpyram, novaluron, novi?umuron, hydroprene, vanilip quinmerac, cumyluron, clacyfos, cliodinate, glyphosate, glu role, vamidothion, parathion, parathion-methyl, halfenprox, fosinate, glufosinate-P, credaZine, clethodim, cloxyfonac, halofenoZide, clodinafop, clodinafop-propargyl, clopyralid, cloproxydim, bistri?uoron, bisultap, hydramethylnon, hydroxy propyl cloprop, clofop, clomazone, chlomethoxynil, chlomethoxy starch, binapacryl, bifenazate, bifenthrin, py?ubumide, fen, clomeprop, chloraZifop, chloraZine, chloranocryl, pymetroZine, pyraclofos, pyra?uprole, pyridafenthion, chloramben, cloransulam, pyridaben, pyridalyl, pyri?uquinazon, pyriprole, pyriproxy cloransulam-methyl, chloridazon, chlorimuron, chlorimu fen, pirimicarb, pyrimidifen, pirimiphos-methyl, pyrethrins, ron-ethyl, chlorsulfuron, chlorthal, chlorthiamid, chlortolu ?pronil, fenazaquin, fenamiphos, phenisobromolate, feni ron, chlomitrofen, chlorfenac, chlorfenprop, chlorbufam, trothion (MEP), fenoxycarb, fenothiocarb, phenothrin, chlor?urazole, chlor?urenol, chlorprocarb, chlorpropham, fenobucarb, fensulfothion, fenthion (MPP), phenthoate chlorbromuron, chlormequat, chloreturon, chloroxynil, (PAP), fenvalerate, fenpyroximate, fenpropathrin, fenbenda chloroxuron, chlorotoluron, chloropon, sa?ufenacil, cyana zole, butathiofos, buproerin, furathiocarb, prallethrin, ?u Zine, cyanatryn, di-allate, diuron, diethamquat, dicamba, acrypyrim, ?uaZinam, ?uazuron, cycluron, cycloate, cycloxydim, diclosulam, cyclosulfamu ?uensulfone, ?ucycloxuron, ?ucythrinate, ?uvalinate, ron, dichlorprop, dichlorprop-P, dichlobenil, diclofop, diclo ?upyradifurone, ?upyrazofos, ?u?prole, ?ufenerim, fop-methyl, dichlormate, dichloralurea, diquat, cisanilide, ?ufenoxuron, ?ufenZine, ?ufenprox, ?uproxyfen, ?ubro disul, siduron, dithiopyr, dinitramine, cinidon-ethyl, cythrinate, ?umethrin, ?urimfen, prothiofos, protrifenbute, dinosam, cinosulfuron, dinoseb, dinoterb, dinofenate, dino ?onicamid, propaphos, propargite (BPPS), pro?uthrin, pro prop, cyhalofop-butyl, diphenamid, difenoxuron, difeno poxur (PHC), ?ometoquin, bromopropylate, beta-cy?uthrin, penten, difenzoquat, cybutryne, cypraZine, cyprazole, hexa?umuron, hexythiazox, heptenophos, permethrin, ben di?ufenican, di?ufenzopyr, dipropetryn, cypromid, cyper clothiaZ, bendiocarb, bensultap, benzoximate, benfuracarb, quat, gibberellin, simaZine, dimidazon, dimexano, dimeth phoxim, phosalone, fosthiazate, fosthietan, phosphamidon, achlor, dimethametryn, dimethenamid, simetryn, simeton, phosphocarb, phosmet (PMP), polynactins, formetanate, for dimepiperate, dimefuron, cinmethylin, swep, sulglycapin, mothion, phorate, machine oil, sulcotrione, sulfallate, sulfentrazone, sulfosulfuron, sulfo malathion, milbemycin, milbemycin-A, milbemectin, mecar meturon, sulfometuron-methyl, secbumeton, sethoxydim, ham, mesulfenfos, methomyl, metaldehyde, meta?umizone, sebuthylaZine, terbacil, daimuron, dazomet, dalapon, thiaZ methamidophos, metam-ammonium, metam-sodium, a?uoron, thiazopyr, thiencarbazone, thiencarbazone-methyl, methiocarb, methidathion (DMTP), methylisothiocyanate, tiocarbaZil, tioclorim, thiobencarb, thidiaZimin, thidiazuron, methylneodecanamide, methylparathion, metoxadiazone, thifensulfuron, thifensulfuron-methyl, desmedipham, desm methoxychlor, methoxyfenozide, meto?uthrin, methoprene, etryn, tetra?uoron, thenylchlor, tebutam, tebuthiuron, terbu metolcarb, meper?uthrin, mevinphos, monocrotophos, meton, tepraloxydim, tefuryltrione, tembotrione, delachlor, monosultap, lambda-cyhalothrin, ryanodine, lufenuron, res terbacil, terbucarb, terbuchlor, terbuthylaZine, terbutryn, methrin, lepimectin, rotenone, levamisole hydrochloride, topramezone, tralkoxydim, triaZi?am, triasulfuron, triafa fenbutatin oxide, morantel tartarate, methyl bromide, tricy mone, tri-allate, trietaZine, tricamba, triclopyr, tridiphane, clohexyltin hydroxide (cyhexatin), calcium cyanamide, cal tritac, tritosulfuron, tri?usulfuron, tri?usulfuron-methyl, tri cium polysul?de, sulfur and nicotine-sulfate. ?uralin, tri?oxysulfuron, tripropindan, [0054] Examples of the agricultural and horticultural her tribenuron, tribenuron-methyl, trifop, trifopsime, trimeturon, bicides include 1-naphthylacetamide, 2,4-PA, 2,3,6-TBA, naptalam, naproanilide, napropamide, nicosulfuron, nitralin, 2,4,5-T, 2,4,5-TB, 2,4-D, 2,4-DB, 2,4-DEB, 2,4-DEP, 3,4 nitrofen, nitro?uorfen, nipyraclofen, neburon, nor?urazon, DA, 3,4-DB, 3,4-DP, 4-CPA (4-chlorophenoxyacetic acid), noruron, barban, paclobutrazol, paraquat, para?uoron, US 2014/0256687 A1 Sep. 11,2014
haloxydine, haloxyfop, haloxyfop-P, haloxyfop-methyl, ?urazole, ?uxofenim, furilazole, mefenpyr-diethyl, MG191, halosafen, halosulfuron, halosulfuron-methyl, bilanafos, oxabetrinil, allidochlor, isoxadifen-ethyl, cyprosulfamide, picloram, picolinafen, bicyclopyrone, bispyribac, bispyribac ?uxofenim and 1,8-naphthalic anhydride. sodium, pydanon, pinoxaden, bifenox, piperophos, hymex azol, pyraclonil, pyrasulfotole, pyrazoxyfen, pyrazosulfuron, EXAMPLES pyrazosulfuron-ethyl, pyrazolate, bilanafos, pyra?ufen [0057] Hereinafter, representative Examples and Test ethyl, pyriclor, pyridafol, Examples in connection with the present invention are shown, pyrithiobac, pyrithiobac-sodium, pyridate, pyri?alid, pyribu but the present invention is not limited thereto. In Examples, ticarb, pyribenzoxim, pyrimisulfan, primisulfuron, pyrimino the “part(s)” means a part(s) by mass. bac-methyl, pyroxasulfone, pyroxsulam, fenasulam, phen isopham, fenuron, fenoxasulfone, fenoxaprop, fenoxaprop-P, Formulation Example 1 fenoxaprop-ethyl, phenothiol, fenoprop, phenobenzuron, fenthiaprop, fenteracol, fentrazamide, phenmedipham, phen Emulsi?able Concentrate medipham-ethyl, butachlor, butafenacil, butamifos, buthi uron, buthidazole, butylate, buturon, butenachlor, butroxy [0058] dim, butralin, butroxydim, ?azasulfuron, ?amprop, furyloxyfen, prynachlor, primisulfuron-methyl, ?uaZifop, Flubendialnide 5 parts ?uaZifop-P, ?uaZifop-butyl, Dichlorvos 10 parts ?uazolate, ?uoroxypyr, ?uothiuron, ?uometuron, ?uorogly Xylene 65 parts N—methyl pyrrolidone 10 parts cofen, ?uorochloridone, ?uorodifen, ?uoronitrofen, ?uoro Mixture of polyoxyethylene nonylphenyl ether 10 parts midine, ?ucarbazone, ?ucarbazone-sodium, ?uchloralin, ?u and calcium alkylbenzene sulfonate cetosulfuron, ?uthiacet, ?uthiacet-methyl, ?upyrsulfuron, ?ufenacet, ?ufenican, ?ufenpyr, ?upropacil, ?upropanate, ?upoxam, ?umiovain, ?umiclorac, ?umiclorac-pentyl, ?u [0059] The above ingredients are mixed and dissolved uni mipropyn, ?umeZin, ?umetsulam, ?uridone, ?urtamone, ?u formly to give an emulsi?able concentrate. oroxypyr, pretilachlor, proxan, proglinaZine, procyaZine, prodiamine, prosulfalin, prosulfuron, Formulation Example 2 prosulfocarb, propaquizafop, propachlor, propaZine, propa nil, propyzamide, propisochlor, prohydrojasmon, propyrisul Dust furon, propham, pro?uazol, pro?uralin, prohexadione-cal [0060] cium, propoxycarbazone, propoxycarbazone-sodium, profoxydim, bromacil, brompyrazon, prometryn, prometon, Flubendialnide 3 parts bromoxynil, bromofenoxim, bromobutide, bromobonil, ?o Profenofos 10 parts rasulam, hexachloroacetone, hevainone, pethoxamid, bena Clay powder 72 parts zolin, penoxsulam, pebulate, be?ubutamid, vemolate, per Diatomite powder 15 parts ?uidone, bencarbazone, benzadox, benZipram, benzylaminopurine, benZthiazuron, beanendizone, ben [0061] The above ingredients are uniformly mixed and then sulide, bensulfuron-methyl, benzoylprop, pulverized to give a dust. benzobicyclon, benzofenap, benzo?uor, bentazone, pen tanochlor, benthiocarb, pendimethalin, pentoxazone, ben?u Formulation Example 3 ralin, benfuresate, fosamine, fomesafen, foramsulfuron, forchlorfenuron, maleic hydraZide, mecoprop, mecoprop-P, Granule medinoterb, mesosulfuron, mesosulfuron-methyl, mesotri one, mesopraZine, methoprotryne, metazachlor, methazole, [0062] metazosulfuron, methabenZthiazuron, metamitron, metami fop, metam, methalpropalin, methiuron, methiozolin, Flubendialnide 1 part methiobencarb, methyldymron, metoxuron, meto sulam, met Dichlorvos 2 parts sulfuron, metsulfuron-methyl, met?urazon, metobromuron, Profenofos 2 parts metobenzuron, methometon, metolachlor, metribuZin, mepi Mixture of bentonite powder and clay powder 90 parts quat-chloride, mefenacet, me?uidide, monalide, monisou Calcium lignosulfonate 5 parts ron, monuron, monochloroacetic acid, monolinuron, moli nate, morfamquat, iodosulfuron, iodosulfuron-methyl [0063] The above ingredients are uniformly mixed. After sodium, iodobonil, iodomethane, lactofen, linuron, addition of an appropriate volume of water, the mixture is rimsulfuron, lenacil, rhodethanil, calcium peroxide and kneaded, granulated and dried to give a granule. methyl bromide. [0055] Examples of the synergists include piperonyl butox Formulation Example 4 ide, sesamex, sulfoxide, N-(2-ethylhexyl)-8,9,10-trinorbom 5-ene-2,3-dicarboximide (MGK 264), N-declyimidazole, Wettable Powder WARF-antiresistant, TBPT, TPP, IBP, PSCP, methyl iodide, t-phenylbutenone, diethyl maleate, DMC, FDMC, ETP and [0064] ETN. [0056] Examples of the phytotoxicity reducers include Flubendialnide 2 parts benoxacor, cloquintocet-mexyl, cyometrinil, daimuron, Dichlorvos 18 parts dichlormid, cyprosulfamide, fenchlorazole-ethyl, fenclorim, US 2014/0256687 A1 Sep. 11,2014 11
-c0ntinued regarded as having not a mere additive effect but a synergistic effect. The results are shown in Table 1. Kaolin and synthetic high—dispersion silicic 75 parts acid
Number of surviving larvae Control effect (%) Expected value (%)
2 days 6 days 2 days 6 days 2 days 6 days Dose Before after after after after after after Test agrochemical (g a.i./ha) treatment treatment treatment treatment treatment treatment treatment
Flubendiamide 60 575 207 30 62 94 49 88 Dichlorvos 400 Flubendiamide 60 373 51 13 86 96 68 98 Profenofos 320 Flubendiamide 60 533 307 56 39 88 i * Dichlorvos 400 236 188 212 16 O i i Profenofos 320 246 121 44 48 80 i i
Non—treatment i 348 329 314 i i i i
The a.i. in the table stands for active ingredient.
-00ntinued Test Example 2
InigstrySo 01 3105 CO_ (MLmanufactured Japan) b y Toho Chemical 5 p arts Control Effect on Chzlo_ suppressalzs_ Propylene glycol 5 parts 151353101’01 23 (manufacmr?d by Rhon?'POUlenc 2 PMS [0075] Rice plants (variety: Kinmaze) were planted in 2-L Wat-6r 58 pans pots and grown to a height of about 80 cm (about 82 days after transplantation, 18 to 25 sheaths). The depth of paddy water [0067] The above 1ngred1ents. . are uniformly. mixed. and then in each p 0t was ad'ustedJ t0 4 cm and then s p ray treatment to dispersed in water to give a ?owable. the rice plants was conducted with an agrochemical solution diluted to a predetermined concentration in an amount Test Example 1 equivalent to 400 L/ha. After the spray-treated plants were air-dried, each pot was covered with a vinyl chloride cylin Control Effect on Plulella xyloslella drical cover 30 cm in height. At 1 day before the treatment and [0068] Transplants ofBrassica oleracea var. capilala (vari at 5 and 12 days after the treatment, 20 larvae of the test insect ety: YR Seitoku) were planted in a glass greenhouse, and in pest Chilo suppressalis were released into each of the covered the 12- t0 15-leaf stage, inoculated with 3rd-instar larvae of pots (60 larvae in total per pot). At 29 days after the treatment, Plulella xyloslella. The number of surviving larvae in three in each pot, the number of damaged stems of the rice plants plants per plot before agrochemical treatment was counted was counted, the percentage of damaged stems was calcu and then spray treatment to the test plants was conducted with lated, and from this percentage, the control effect was calcu an agrochemical solution diluted to a predetermined concen lated according to formula 2. In addition, the expected value tration in an amount equivalent to 800 L/ha. The number of was calculated according to Colby’s equation in the same surviving larvae was counted at 2 and 6 days after the spray treatment and the control effect was calculated according to manner as in Test Example 1. The results are shown in Table formula 1. In addition, the expected value for the control 2. effect of the mixed use was calculated according to Colby’s Control effect (%):100—(the percentage of damaged equation shown below. When the control effect of the mixed stems in a treatment plot/the percentage of dam— use is superior to the expected value, the mixed use is aged stems in a non—treatment plot)><100
TABLE 2
Number of stems at 29 days Percentage of Dose after treatment damaged stems Percentage of Expected
Test agrochemical (g a.i./ha) Normal stems Damaged stems (%) control (%) value (%)
Flubendiamide 30 58 0 0 100 57.5 Dichlorvos 393 Flubendiamide 30 49 2 3.9 95.7 66.7 Profenofos 500 Flubendiamide 30 29 21 42.0 54.0 i Dichlorvos 393 7 3 8 84.4 7.5 i Profenofos 500 18 35 66.0 27.7 i Non—treatment i 4 42 91.3 i i
The a.i. in the table stands for active ingredient.
[0076] In each test, the control effects observed in (i) the effective amount of an optionally diluted formulation con ?ubendiamide and dichlorvos mixed treatment plot and in (ii) taining ?ubendiamide as an active ingredient and an effective the ?ubendiamide and profenofos mixed treatment plot were amount of an optionally diluted formulation containing greater than the expected effect (expected value) calculated dichlorvos and/or profenofos as an active ingredient(s), the from the effect observed in the ?ubendiamide treatment plot two formulations being used separately but in the same and the effect observed in the dichlorvos or profenofos treat period. ment plot. 5. A method for controlling agricultural and horticultural 1. An agricultural and horticultural insecticide composi insect pests, comprising treating insect pests directly, treating tion comprising ?ubendiamide and dichlorvos and/or pro crops potentially infested with the insect pests, or treating fenofos as active ingredients. surrounding soil or cultivation medium of the crops with an 2. The agricultural and horticultural insecticide composi effective amount of an optionally diluted formulation con tion according to claim 1, comprising 0.1 to 10 parts by mass taining ?ubendiamide as an active ingredient and an effective of dichlorvos and/or profenofos per part by mass of ?uben amount of an optionally diluted formulation containing diamide. dichlorvos and/or profenofos as an active ingredient(s), the 3. A method for using an agricultural and horticultural two formulations being used separately at a given interval. insecticide composition, comprising treating insect pests 6. A method for controlling agricultural and horticultural directly, treating crops potentially infested with the insect insect pests, comprising mixing an effective amount of a pests, or treating surrounding soil or cultivation medium of formulation containing ?ubendiamide as an active ingredient the crops with an effective amount of an agricultural and and an effective amount of a formulation containing dichlo horticultural insecticide composition comprising ?ubendia rvos and/or profenofos as an active ingredient(s), optionally mide and dichlorvos and/or profenofos as active ingredients. diluting the mixture; and treating insect pests directly, treat 4. A method for controlling agricultural and horticultural ing crops potentially infested with the insect pests, or treating insect pests, comprising treating insect pests directly, treating surrounding soil or cultivation medium of the crops with the crops potentially infested with the insect pests, or treating optionally diluted mixture. surrounding soil or cultivation medium of the crops with an * * * * *