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Emerging Issues in Control: The Rise of Electronic Products and Implications for Policy, Planning, and Practice

BRIAN A. KING, PHD, MPH DEPUTY DIRECTOR FOR RESEARCH TRANSLATION OFFICE ON AND HEALTH Wisconsin Department of Health Services ● January 15, 2019

1 What Are They?

Why Are They 2 Popular?

Who’s Using 3 Them?

4 Are They Safe?

What Can We 5 Do About it?

1 What Are They?

Why Are They 2 Popular?

Who’s Using 3 Them?

4 Are They Safe?

What Can We 5 Do About it?

The Bad News: The Landscape Is Evolving

Cigars, Little Cigars

Smokeless Pipes

Tobacco Snus Hookah

Bidis Dissolvables

Kreteks E-cigarettes

Heated Tobacco Products E-cigarettes: A Rapidly Diversifying Class The Rise of Additional USB-shaped e-cigarettes are increasingly available -- Brand examples

MarkTen Elite () myBlu (Imperial Tobacco) Alto (RJR) “Coming Soon”

Myle Phix SmokTech’s “Fit” Vapeccino’s MATE1 Coilart’s UME

Source: Campaign for Tobacco-Free Kids Additional E- Shapes

Suorin Drop Suorin KandyPens’ Daze Air Feather Mfg’s ZOOR

Source: Campaign for Tobacco-Free Kids What Are “Heat Not Burn” Products?

Contain Tobacco

Throat Hit Similar to Cigarettes Crosswalking Heated Tobacco Products, E-cigarettes, and Conventional Cigarettes

Characteristics* HTPs E-cigarettes Manufactured Cigarettes Electronic

Flame-activated

Contain tobacco leaf

Can deliver

Produce secondhand emissions Produce smoke

Can deliver marijuana

*Sometimes or always 10 HTPs Pending FDA Pre-Market Approval

A scientific advisory committee met to discuss the MRTP application in January 2018.

Philip Morris International submitted applications to FDA for approval to: • Market iQOS (“Premarket Tobacco Product Application” or PMTA) • Make health claims (“Modified Risk Tobacco Product” application or MRTP)

1 What Are They?

Why Are They 2 Popular?

Who’s Using 3 Them?

4 Are They Safe?

What Can We 5 Do About it?

Youth E-cigarette Initiation and Use

Advertising Nicotine Youth Exposure to E-cigarette Use of Flavors is Prominent Among Youth

1 What Are They?

Why Are They 2 Popular?

Who’s Using 3 Them?

4 Are They Safe?

What Can We 5 Do About it?

Ever Use of E-cigarettes Among Adults, by Cigarette Smoking Status—U.S., 2010-2017

60 Current Cigarette Smoker 53.5

50 Former Cigarette Smoker 50.3 44.9 46.7 Never Cigarette Smoker 40

36.5

30 31.2 Percentage (%) Percentage 21.2 17.8 20 16.3 19.3 14.7 9.6 10 9.8 7.4 5.7 6.7 5.9 4.7 6.1 2.5 1.3 2.3 1.2 1.3 0 2010 2011 2012 2013 2014 2015 2016 2017 Year

Source: CDC. Styles Survey. 2010-2017 A Majority of Adult E-cigarette Users Also Smoke Conventional Cigarettes Cigarette smoking status among current adult e-cigarette users, by age group

Source: QuickStats: Cigarette Smoking Status Among Current Adult E-cigarette Users, by Age Group — National Health Interview Survey, , 2015. MMWR Morb Mortal Wkly Rep 2016;65:1177. Current Use of E-cigarettes and Any Tobacco Product Among Middle and High School Students— NYTS, US, 2011–2018

Source: Cullen KA, Ambrose BK, Gentzke AS, Apelberg BJ, Jamal A, King BA. Notes from the Field: Use of Electronic Cigarettes and Any Tobacco Product Among Middle and High School Students — United States, 2011–2018. MMWR Morb Mortal Wkly Rep 2018;67:1276–1277. JUUL use, access points, and misperceptions among young people

1 in 5 middle and high school students have seen JUUL used 11 at school 10

8

6 3 in 4 youth who used JUUL say they got the device from a physical retail location

15-17 18-21 63% of JUUL users ages 15-24 Ever Use Current Use did not know nicotine is always in the device

Source: Willett JG, Bennett M, Hair EC, et al Recognition, use and perceptions of JUUL among youth and young adults Published Online First: 18 April 2018. Vallone DM, Bennett M, Xiao H, et al.Prevalence and correlates of JUUL use among a national sample of youth and young adults Tobacco Control Published Online First: 29 October 2018. doi: 10.1136/tobaccocontrol-2018-054693

1 What Are They?

Why Are They 2 Popular?

Who’s Using 3 Them?

4 Are They Safe?

What Can We 5 Do About it?

Net Benefit or Harm?

Youth Initiation Adult Cessation E-Cigarette Use As A Smoking Cessation Tool in Adults

“Overall, the USPSTF found the evidence on the use of “The long-term safety of ENDS as a smoking cessation e-cigarettes is unknown.” tool in adults, including pregnant women, and adolescents to be insufficient.”

Conclusion 17-1. Overall, there is limited evidence that e-cigarettes may be effective aids to promote smoking cessation.

Source: The National Academies of Science, Engineering, and Medicine. Public Health Consequences of E-cigarettes. 2018. www.uspreventiveservicestaskforce.org

Potential Health Risks of E-cigarettes

Leads to Exposes initiation of Leads to Diminishes Discourages children, Results in combustible relapse the chances smokers pregnant Glamorizes poisonings tobacco use among that a from using women, or among among non- and non- renormalizes smokers, former smoker will proven quit users to tobacco use users or particularly smokers quit methods secondhand non-users children aerosol Nicotine salts allow particularly high levels of nicotine to be inhaled easilyJuul andContains with less irritationNicotine than Salts free base nicotine

Benzoic Acid

Nicotine Free00 Base Salts Nicotine

1 What Are They?

Why Are They 2 Popular?

Who’s Using 3 Them?

4 Are They Safe?

What Can We 5 Do About it?

Major Conclusion #7

“Action can be taken at the national, state, local, tribal, and territorial levels to address e-cigarette use among youth and young adults. Actions could include incorporating e-cigarettes into smoke- free policies, preventing access to e- cigarettes by youth, price and tax policies, retail licensure, regulation of e-cigarette marketing likely to attract youth, and educational initiatives targeting youth and young adults.” Public Health Actions to Address E-Cigarettes

Federal Regulation State, Local, Territory Family Smoking Prevention Potential Sub-National Action: and Tobacco Control Act

• Signed into law on June 22, 2009 • Including e-cigarettes in smokefree • Granted FDA the authority to indoor air policies regulate tobacco products • Restricting youth access to e-cigarette • Enhanced the ability to intensify in retail settings policy to reduce • Licensing retailers influence: • Establishing specific package • Manufacturing requirements • Marketing • Setting price policies • Sale

E-cigarettes are a tobacco product that produces an aerosol Whatby heating aAre liquid thatThey? typically 1 contains nicotine, flavorings, and other chemicals.

Several factors have contributedWhy toAre the popularity They of e-cigarettes, including 2 advertisingPopular? and the vast array of available flavors.

E-cigarette use is higher among youngWho’s people than Using adults. As of 2014, e-cigarettes were the most 3 commonlyThem? used tobacco product among U.S. youth.

Youth use of e-cigarettes is unsafe. Adult smokers must completelyAre They quit to realize Safe? 4 benefits from e-cigarettes.

As the tobacco product landscape continuesWhat to diversify, Can it’s We important to modernize tobacco 5 controlDo strategies About to adapt. it?